Table A

Table B

Annex A

 

Table A: [As supplied by authors] Costs, effectiveness and cost-effectiveness ratios of all interventions and combinations for Afr-E in 2000 international dollars

          

No.

Description of intervention

Yearly Costs (millions Int$)

Yearly DALYs averted (millions)

ACER (I$ per DALY averted)

ICER (I$ per DALY averted)

 

 

 

 

          

1

Oral Rehydration Therapy (ORT) (@50%)

$237

2.18

$109

Dominated

    

2

Oral Rehydration Therapy (@80%)

$422

3.48

$121

Dominated

    

3

Oral Rehydration Therapy (@95%)

$577

4.14

$139

Dominated

    

4

Case management for childhood pneumonia (CM) (@50%)

$94

1.52

$62

Dominated

    

5

Case management for childhood pneumonia (@80%)

$174

2.43

$72

Dominated

    

6

Case management for childhood pneumonia (@95%)

$249

2.88

$87

Dominated

    

7

Vitamin A supplementation (@50%)

$26

0.51

$52

Dominated

    

8

Vitamin A supplementation (@80%)

$136

0.81

$168

Dominated

    

9

Vitamin A supplementation (@95%)

$250

0.96

$260

Dominated

    

10

Vitamin A fortification (@50%)

$10

0.24

$41

Dominated

    

11

Vitamin A fortification (@80%)

$13

0.38

$34

Dominated

    

12

Vitamin A fortification (@95%)

$14

0.45

$32

Dominated

    

13

Provision of supplementary food and nutrition counselling (SF) (@50%)

$1,741

0.04

$42,340

Dominated

    

14

Provision of supplementary food and nutrition counselling (@80%)

$2,793

0.07

$42,460

Dominated

    

15

Provision of supplementary food and nutrition counselling (@95%)

$3,334

0.08

$42,680

Dominated

    

16

Provision of supplementary food and nutrition counselling with growth monitoring (SFGM) (@50%)

$918

0.04

$22,320

Dominated

    

17

Provision of supplementary food and nutrition counselling with growth monitoring @80%)

$1,476

0.07

$22,428

Dominated

    

18

Provision of supplementary food and nutrition counselling with growth monitoring @95%)

$1,769

0.08

$22,649

Dominated

    

19

Zinc supplementation (@50%)

$20

0.16

$120

Dominated

    

20

Zinc supplementation (@80%)

$31

0.26

$117

Dominated

    

21

Zinc supplementation (@95%)

$38

0.31

$122

Dominated

    

22

Zinc fortification (@50%)

$7

0.08

$82

Dominated

    

23

Zinc fortification (@80%)

$8

0.13

$60

Dominated

    

24

Zinc fortification (@95%)

$9

0.16

$55

Dominated

    

25

ORT & CM (@50%)

$307

3.72

$83

Dominated

    

26

ORT & CM (@80%)

$552

5.95

$93

Dominated

    

27

ORT & CM (@95%)

$765

7.07

$108

Dominated

    

28

Vit A. Fort. & Zinc Fort. (@50%)

$15

0.63

$24

Dominated

    

29

Vit A. Fort. & Zinc Fort. (@80%)

$20

1.01

$20

Dominated

    

30

Vit A. Fort. & Zinc Fort. (@95%)

$23

1.20

$19

$19

    

31

Zinc Fort & CM (@50%)

$109

1.67

$66

Dominated

    

32

Zinc Fort & CM (@80%)

$194

2.66

$73

Dominated

    

33

Zinc Fort & CM (@95%)

$272

3.16

$86

Dominated

    

34

Vit. A Suppl. & Zinc Suppl. (@50%)

$95

1.55

$61

Dominated

    

35

Vit. A Suppl. & Zinc Suppl. (@80%)

$180

2.47

$73

Dominated

    

36

Vit. A Suppl. & Zinc Suppl. (@95%)

$265

2.94

$90

Dominated

    

37

Zinc Suppl. & Zinc Fort (@50%)

$48

0.14

$341

Dominated

    

38

Zinc Suppl. & Zinc Fort (@80%)

$78

0.22

$348

Dominated

    

39

Zinc Suppl. & Zinc Fort (@95%)

$104

0.27

$391

Dominated

    

40

Vit. A Fort., Zinc Fort.& ORT (@50%)

$252

2.82

$89

Dominated

    

41

Vit. A Fort., Zinc Fort.& ORT (@80%)

$441

4.51

$98

Dominated

    

42

Vit. A Fort., Zinc Fort.& ORT (@95%)

$598

5.35

$112

Dominated

    

43

Vit. A Fort., Zinc Fort. & CM (@50%)

$109

2.21

$49

Dominated

    

44

Vit. A Fort., Zinc Fort. & CM (@80%)

$194

3.54

$55

Dominated

    

45

Vit. A Fort., Zinc Fort. & CM (@95%)

$272

4.20

$65

Dominated

    

46

Zinc Fort., ORT & CM (@50%)

$313

3.87

$81

Dominated

    

47

Zinc Fort., ORT & CM (@80%)

$560

6.19

$90

Dominated

    

48

Zinc Fort., ORT & CM (@95%)

$881

7.35

$120

Dominated

    

49

Zinc Suppl., ORT & CM (@50%)

$328

3.97

 

Dominated

    

50

Zinc Suppl., ORT & CM (@80%)

$588

6.35

$92

Dominated

    

51

Zinc Suppl., ORT & CM (@95%)

$812

7.55

$108

Dominated

    

52

Vit. A Suppl., Zinc Suppl., & CM (@50%)

$170

3.13

$54

Dominated

    

53

Vit. A Suppl., Zinc Suppl., & CM (@80%)

$319

5.01

$64

Dominated

    

54

Vit. A Suppl., Zinc Suppl., & CM (@95%)

$466

5.95

$78

Dominated

    

55

Vit. A Suppl., Zinc Suppl., & ORT (@50%)

$313

3.72

$84

Dominated

    

56

Vit. A Suppl., Zinc Suppl., & ORT (@80%)

$567

5.96

$95

Dominated

    

57

Vit. A Suppl., Zinc Suppl., & ORT (@95%)

$793

7.08

$112

Dominated

    

58

Vit. A Suppl., Zinc Suppl., ORT & CM (@50%)

$386

5.41

$71

Dominated

    

59

Vit. A Suppl., Zinc Suppl., ORT & CM (@80%)

$705

8.66

$81

Dominated

    

60

Vit. A Suppl., Zinc Suppl., ORT & CM (@95%)

$1,099

10.28

$107

Dominated

    

61

Vit. A Fort., Zinc Fort., ORT & CM (@50%)

$321

4.45

$72

Dominated

    

62

Vit. A Fort., Zinc Fort., ORT & CM (@80%)

$571

7.12

$80

Dominated

    

63

Vit. A Fort., Zinc Fort., ORT & CM (@95%)

$786

8.46

$93

Dominated

    

64

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@50%)

$110

0.74

$150

Dominated

    

65

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@80%)

$200

1.18

$170

Dominated

    

66

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@95%)

$288

1.40

$206

Dominated

    

67

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@50%)

$1,289

5.48

$235

Dominated

    

68

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@80%)

$2,157

8.77

$246

Dominated

    

69

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@95%)

$2,730

10.41

$262

Dominated

    

70

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@50%)

$1,224

4.48

$273

Dominated

    

71

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@80%)

$2,022

7.17

$282

Dominated

    

72

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@95%)

$2,632

8.52

$309

Dominated

    

73

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@50%)

$185

2.32

$80

Dominated

    

74

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@80%)

$339

3.71

$91

Dominated

    

75

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@95%)

$489

4.41

$111

Dominated

    

76

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@50%)

$401

4.56

$88

Dominated

    

77

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@80%)

$725

7.29

$99

Dominated

    

78

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@95%)

$1,123

8.66

$130

Dominated

    

79

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@50%)

$1,303

4.59

$284

Dominated

    

80

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@80%)

$2,175

7.35

$296

Dominated

    

81

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@95%)

$2,859

8.73

$327

Dominated

    

82

Vit A. Fort. & Zinc Fort. (@50%) + Measles immunisation (@50%)

$50

1.69

$30

Dominated

    

83

Vit A. Fort. & Zinc Fort. (@80%) + Measles immunisation (@50%)

$56

2.07

$27

Dominated

    

84

Vit A. Fort. & Zinc Fort. (@95%) + Measles immunisation (@50%)

$59

2.26

$26

Dominated

    

85

Zinc Fort & CM (@50%) + Measles immunisation (@50%)

$145

2.73

$53

Dominated

    

86

Zinc Fort & CM (@80%) + Measles immunisation (@50%)

$229

3.73

$61

Dominated

    

87

Zinc Fort & CM (@95%) + Measles immunisation (@50%)

$307

4.23

$73

Dominated

    

88

Vit. A Suppl. & Zinc Suppl. (@50%) + Measles immunisation (@50%)

$130

2.61

$50

Dominated

    

89

Vit. A Suppl. & Zinc Suppl. (@80%) + Measles immunisation (@50%)

$215

3.54

$61

Dominated

    

90

Vit. A Suppl. & Zinc Suppl. (@95%) + Measles immunisation (@50%)

$300

4.00

$75

Dominated

    

91

Zinc Suppl. & Zinc Fort (@50%) + Measles immunisation (@50%)

$83

1.20

$69

Dominated

    

92

Zinc Suppl. & Zinc Fort (@80%) + Measles immunisation (@50%)

$113

1.29

$88

Dominated

    

93

Zinc Suppl. & Zinc Fort (@95%) + Measles immunisation (@50%)

$139

1.33

$105

Dominated

    

94

Vit. A Fort., Zinc Fort.& ORT (@50%) + Measles immunisation (@50%)

$287

3.88

$74

Dominated

    

95

Vit. A Fort., Zinc Fort.& ORT (@80%) + Measles immunisation (@50%)

$476

5.57

$85

Dominated

    

96

Vit. A Fort., Zinc Fort.& ORT (@95%) + Measles immunisation (@50%)

$633

6.42

$99

Dominated

    

97

Vit. A Fort., Zinc Fort. & CM (@50%) + Measles immunisation (@50%)

$145

3.28

$44

Dominated

    

98

Vit. A Fort., Zinc Fort. & CM (@80%) + Measles immunisation (@50%)

$229

4.60

$50

Dominated

    

99

Vit. A Fort., Zinc Fort. & CM (@95%) + Measles immunisation (@50%)

$307

5.27

$58

Dominated

    

100

Zinc Fort., ORT & CM (@50%) + Measles immunisation (@50%)

$349

4.94

$71

Dominated

    

101

Zinc Fort., ORT & CM (@80%) + Measles immunisation (@50%)

$595

7.26

$82

Dominated

    

102

Zinc Fort., ORT & CM (@95%) + Measles immunisation (@50%)

$916

8.42

$109

Dominated

    

103

Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@50%)

$363

5.04

$72

Dominated

    

104

Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@50%)

$623

7.42

$84

Dominated

    

105

Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@50%)

$847

8.61

$98

Dominated

    

106

Vit. A Suppl., Zinc Suppl., & CM (@50%) + Measles immunisation (@50%)

$205

4.19

$49

Dominated

    

107

Vit. A Suppl., Zinc Suppl., & CM (@80%) + Measles immunisation (@50%)

$354

6.07

$58

Dominated

    

108

Vit. A Suppl., Zinc Suppl., & CM (@95%) + Measles immunisation (@50%)

$501

7.01

$71

Dominated

    

109

Vit. A Suppl., Zinc Suppl., & ORT (@50%) + Measles immunisation (@50%)

$348

4.79

$73

Dominated

    

110

Vit. A Suppl., Zinc Suppl., & ORT (@80%) + Measles immunisation (@50%)

$602

7.02

$86

Dominated

    

111

Vit. A Suppl., Zinc Suppl., & ORT (@95%) + Measles immunisation (@50%)

$828

8.14

$102

Dominated

    

112

Vit. A Suppl., Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@50%)

$421

6.48

$65

Dominated

    

113

Vit. A Suppl., Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@50%)

$740

9.73

$76

Dominated

    

114

Vit. A Suppl., Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@50%)

$1,135

11.35

$100

Dominated

    

115

Vit. A Fort., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@50%)

$356

5.51

$65

Dominated

    

116

Vit. A Fort., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@50%)

$606

8.18

$74

Dominated

    

117

Vit. A Fort., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@50%)

$821

9.52

$86

Dominated

    

118

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@50%) + Measles immunisation (@50%)

$145

1.80

$81

Dominated

    

119

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@80%) + Measles immunisation (@50%)

$235

2.24

$105

Dominated

    

120

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@95%) + Measles immunisation (@50%)

$323

2.46

$131

Dominated

    

121

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@50%) + Measles immunisation (@50%)

$1,324

6.54

$202

Dominated

    

122

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@80%) + Measles immunisation (@50%)

$2,192

9.83

$223

Dominated

    

123

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@95%) + Measles immunisation (@50%)

$2,765

11.48

$241

Dominated

    

124

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@50%)

$1,259

5.55

$227

Dominated

    

125

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@50%)

$2,058

8.24

$250

Dominated

    

126

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@50%)

$2,667

9.58

$278

Dominated

    

127

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@50%) + Measles immunisation (@50%)

$220

3.38

$65

Dominated

    

128

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@80%) + Measles immunisation (@50%)

$375

4.77

$78

Dominated

    

129

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@95%) + Measles immunisation (@50%)

$524

5.47

$96

Dominated

    

130

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@50%)

$437

5.62

$78

Dominated

    

131

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@50%)

$760

8.36

$91

Dominated

    

132

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@50%)

$1,158

9.73

$119

Dominated

    

133

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@50%)

$1,338

5.66

$237

Dominated

    

134

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@50%)

$2,211

8.42

$263

Dominated

    

135

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@50%)

$2,894

9.79

$295

Dominated

    

136

Vit A. Fort. & Zinc Fort. (@50%) + Measles immunisation (@80%)

$64

2.33

$27

Dominated

    

137

Vit A. Fort. & Zinc Fort. (@80%) + Measles immunisation (@80%)

$69

2.71

$26

Dominated

    

138

Vit A. Fort. & Zinc Fort. (@95%) + Measles immunisation (@80%)

$72

2.90

$25

$29

    

139

Zinc Fort & CM (@50%) + Measles immunisation (@80%)

$158

3.37

$47

Dominated

    

140

Zinc Fort & CM (@80%) + Measles immunisation (@80%)

$243

4.37

$56

Dominated

    

141

Zinc Fort & CM (@95%) + Measles immunisation (@80%)

$321

4.87

$66

Dominated

    

142

Vit. A Suppl. & Zinc Suppl. (@50%) + Measles immunisation (@80%)

$144

3.25

$44

Dominated

    

143

Vit. A Suppl. & Zinc Suppl. (@80%) + Measles immunisation (@80%)

$229

4.18

$55

Dominated

    

144

Vit. A Suppl. & Zinc Suppl. (@95%) + Measles immunisation (@80%)

$314

4.64

$68

Dominated

    

145

Zinc Suppl. & Zinc Fort (@50%) + Measles immunisation (@80%)

$97

1.84

$52

Dominated

    

146

Zinc Suppl. & Zinc Fort (@80%) + Measles immunisation (@80%)

$127

1.93

$66

Dominated

    

147

Zinc Suppl. & Zinc Fort (@95%) + Measles immunisation (@80%)

$153

1.97

$78

Dominated

    

148

Vit. A Fort., Zinc Fort.& ORT (@50%) + Measles immunisation (@80%)

$301

4.52

$67

Dominated

    

149

Vit. A Fort., Zinc Fort.& ORT (@80%) + Measles immunisation (@80%)

$490

6.21

$79

Dominated

    

150

Vit. A Fort., Zinc Fort.& ORT (@95%) + Measles immunisation (@80%)

$647

7.05

$92

Dominated

    

151

Vit. A Fort., Zinc Fort. & CM (@50%) + Measles immunisation (@80%)

$158

3.92

$40

Dominated

    

152

Vit. A Fort., Zinc Fort. & CM (@80%) + Measles immunisation (@80%)

$243

5.24

$46

Dominated

    

153

Vit. A Fort., Zinc Fort. & CM (@95%) + Measles immunisation (@80%)

$321

5.91

$54

Dominated

    

154

Zinc Fort., ORT & CM (@50%) + Measles immunisation (@80%)

$362

5.57

$65

Dominated

    

155

Zinc Fort., ORT & CM (@80%) + Measles immunisation (@80%)

$609

7.90

$77

Dominated

    

156

Zinc Fort., ORT & CM (@95%) + Measles immunisation (@80%)

$930

9.06

$103

Dominated

    

157

Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@80%)

$377

5.67

$66

Dominated

    

158

Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@80%)

$637

8.06

$79

Dominated

    

159

Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@80%)

$861

9.25

$93

Dominated

    

160

Vit. A Suppl., Zinc Suppl., & CM (@50%) + Measles immunisation (@80%)

$219

4.83

$45

Dominated

    

161

Vit. A Suppl., Zinc Suppl., & CM (@80%) + Measles immunisation (@80%)

$368

6.71

$55

Dominated

    

162

Vit. A Suppl., Zinc Suppl., & CM (@95%) + Measles immunisation (@80%)

$515

7.65

$67

Dominated

    

163

Vit. A Suppl., Zinc Suppl., & ORT (@50%) + Measles immunisation (@80%)

$362

5.43

$67

Dominated

    

164

Vit. A Suppl., Zinc Suppl., & ORT (@80%) + Measles immunisation (@80%)

$616

7.66

$80

Dominated

    

165

Vit. A Suppl., Zinc Suppl., & ORT (@95%) + Measles immunisation (@80%)

$842

8.78

$96

Dominated

    

166

Vit. A Suppl., Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@80%)

$435

7.12

$61

Dominated

    

167

Vit. A Suppl., Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@80%)

$754

10.36

$73

Dominated

    

168

Vit. A Suppl., Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@80%)

$1,148

11.99

$96

Dominated

    

169

Vit. A Fort., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@80%)

$370

6.15

$60

Dominated

    

170

Vit. A Fort., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@80%)

$620

8.82

$70

Dominated

    

171

Vit. A Fort., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@80%)

$835

10.16

$82

Dominated

    

172

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@50%) + Measles immunisation (@80%)

$159

2.44

$65

Dominated

    

173

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@80%) + Measles immunisation (@80%)

$249

2.88

$86

Dominated

    

174

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@95%) + Measles immunisation (@80%)

$337

3.10

$109

Dominated

    

175

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@50%) + Measles immunisation (@80%)

$1,338

7.18

$186

Dominated

    

176

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@80%) + Measles immunisation (@80%)

$2,206

10.47

$211

Dominated

    

177

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@95%) + Measles immunisation (@80%)

$2,779

12.11

$229

Dominated

    

178

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@80%)

$1,273

6.19

$206

Dominated

    

179

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@80%)

$2,071

8.88

$233

Dominated

    

180

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@80%)

$2,681

10.22

$262

Dominated

    

181

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@50%) + Measles immunisation (@80%)

$234

4.02

$58

Dominated

    

182

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@80%) + Measles immunisation (@80%)

$388

5.41

$72

Dominated

    

183

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@95%) + Measles immunisation (@80%)

$538

6.11

$88

Dominated

    

184

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@80%)

$450

6.26

$72

Dominated

    

185

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@80%)

$774

9.00

$86

Dominated

    

186

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@80%)

$1,172

10.36

$113

Dominated

    

187

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@80%)

$1,352

6.30

$215

Dominated

    

188

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@80%)

$2,224

9.05

$246

Dominated

    

189

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@80%)

$2,908

10.43

$279

Dominated

    

190

Vit A. Fort. & Zinc Fort. (@50%) + Measles immunisation (@95%)

$83

2.65

$31

Dominated

    

191

Vit A. Fort. & Zinc Fort. (@80%) + Measles immunisation (@95%)

$88

3.03

$29

Dominated

    

192

Vit A. Fort. & Zinc Fort. (@95%) + Measles immunisation (@95%)

$91

3.22

$28

$58

    

193

Zinc Fort & CM (@50%) + Measles immunisation (@95%)

$177

3.69

$48

Dominated

    

194

Zinc Fort & CM (@80%) + Measles immunisation (@95%)

$261

4.69

$56

Dominated

    

195

Zinc Fort & CM (@95%) + Measles immunisation (@95%)

$340

5.19

$65

Dominated

    

196

Vit. A Suppl. & Zinc Suppl. (@50%) + Measles immunisation (@95%)

$163

3.57

$46

Dominated

    

197

Vit. A Suppl. & Zinc Suppl. (@80%) + Measles immunisation (@95%)

$247

4.50

$55

Dominated

    

198

Vit. A Suppl. & Zinc Suppl. (@95%) + Measles immunisation (@95%)

$332

4.96

$67

Dominated

    

199

Zinc Suppl. & Zinc Fort (@50%) + Measles immunisation (@95%)

$115

2.16

$53

Dominated

    

200

Zinc Suppl. & Zinc Fort (@80%) + Measles immunisation (@95%)

$145

2.25

$65

Dominated

    

201

Zinc Suppl. & Zinc Fort (@95%) + Measles immunisation (@95%)

$171

2.29

$75

Dominated

    

202

Vit. A Fort., Zinc Fort.& ORT (@50%) + Measles immunisation (@95%)

$319

4.84

$66

Dominated

    

203

Vit. A Fort., Zinc Fort.& ORT (@80%) + Measles immunisation (@95%)

$508

6.53

$78

Dominated

    

204

Vit. A Fort., Zinc Fort.& ORT (@95%) + Measles immunisation (@95%)

$666

7.37

$90

Dominated

    

205

Vit. A Fort., Zinc Fort. & CM (@50%) + Measles immunisation (@95%)

$177

4.23

$42

Dominated

    

206

Vit. A Fort., Zinc Fort. & CM (@80%) + Measles immunisation (@95%)

$261

5.56

$47

$73

    

207

Vit. A Fort., Zinc Fort. & CM (@95%) + Measles immunisation (@95%)

$340

6.23

$55

Dominated

    

208

Zinc Fort., ORT & CM (@50%) + Measles immunisation (@95%)

$381

5.89

$65

Dominated

    

209

Zinc Fort., ORT & CM (@80%) + Measles immunisation (@95%)

$627

8.22

$76

Dominated

    

210

Zinc Fort., ORT & CM (@95%) + Measles immunisation (@95%)

$949

9.38

$101

Dominated

    

211

Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@95%)

$395

5.99

$66

Dominated

    

212

Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@95%)

$655

8.38

$78

Dominated

    

213

Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@95%)

$879

9.57

$92

Dominated

    

214

Vit. A Suppl., Zinc Suppl., & CM (@50%) + Measles immunisation (@95%)

$237

5.15

$46

Dominated

    

215

Vit. A Suppl., Zinc Suppl., & CM (@80%) + Measles immunisation (@95%)

$386

7.03

$55

$85

    

216

Vit. A Suppl., Zinc Suppl., & CM (@95%) + Measles immunisation (@95%)

$533

7.97

$67

Dominated

    

217

Vit. A Suppl., Zinc Suppl., & ORT (@50%) + Measles immunisation (@95%)

$380

5.75

$66

Dominated

    

218

Vit. A Suppl., Zinc Suppl., & ORT (@80%) + Measles immunisation (@95%)

$634

7.98

$79

Dominated

    

219

Vit. A Suppl., Zinc Suppl., & ORT (@95%) + Measles immunisation (@95%)

$860

9.10

$95

Dominated

    

220

Vit. A Suppl., Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@95%)

$454

7.44

$61

Dominated

    

221

Vit. A Suppl., Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@95%)

$772

10.68

$72

$106

    

222

Vit. A Suppl., Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@95%)

$1,167

12.31

$95

$243

    

223

Vit. A Fort., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@95%)

$389

6.47

$60

Dominated

    

224

Vit. A Fort., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@95%)

$639

9.14

$70

Dominated

    

225

Vit. A Fort., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@95%)

$854

10.48

$81

Dominated

    

226

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@50%) + Measles immunisation (@95%)

$178

2.76

$64

Dominated

    

227

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@80%) + Measles immunisation (@95%)

$268

3.20

$84

Dominated

    

228

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@95%) + Measles immunisation (@95%)

$356

3.42

$104

Dominated

    

229

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@50%) + Measles immunisation (@95%)

$1,356

7.50

$181

Dominated

    

230

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@80%) + Measles immunisation (@95%)

$2,224

10.79

$206

Dominated

    

231

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@95%) + Measles immunisation (@95%)

$2,797

12.43

$225

$12,791

    

232

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@95%)

$1,291

6.51

$198

Dominated

    

233

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@95%)

$2,090

9.20

$227

Dominated

    

234

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@95%)

$2,699

10.54

$256

Dominated

    

235

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@50%) + Measles immunisation (@95%)

$252

4.34

$58

Dominated

    

236

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@80%) + Measles immunisation (@95%)

$407

5.73

$71

Dominated

    

237

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@95%) + Measles immunisation (@95%)

$556

6.43

$87

Dominated

    

238

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@95%)

$469

6.58

$71

Dominated

    

239

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@95%)

$793

9.32

$85

Dominated

    

240

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@95%)

$1,190

10.68

$111

Dominated

    

241

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@95%)

$1,371

6.62

$207

Dominated

    

242

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@95%)

$2,243

9.37

$239

Dominated

    

243

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@95%)

$2,926

10.75

$272

Dominated

    

 

 

 

Table B: [As supplied by authors] Costs, effectiveness and cost-effectiveness ratios of all interventions and combinations for Sear-D in 2000 international dollars

No.

Description of intervention

Yearly Costs (millions Int$)

Yearly DALYs averted (millions)

ACER ($ per DALY averted)

ICER ($ per DALY averted)

        

1

Oral Rehydration Therapy (ORT) (@50%)

$497

2.84

$175

Dominated

  

2

Oral Rehydration Therapy (@80%)

$799

4.55

$176

Dominated

  

3

Oral Rehydration Therapy (@95%)

$998

5.40

$185

Dominated

  

4

Case management for childhood pneumonia (CM) (@50%)

$201

2.65

$76

Dominated

  

5

Case management for childhood pneumonia (@80%)

$323

4.23

$76

Dominated

  

6

Case management for childhood pneumonia (@95%)

$421

5.03

$84

Dominated

  

7

Vitamin A supplementation (@50%)

$50

0.13

$377

Dominated

  

8

Vitamin A supplementation (@80%)

$295

0.21

$1,378

Dominated

  

9

Vitamin A supplementation (@95%)

$429

0.25

$1,686

Dominated

  

10

Vitamin A fortification (@50%)

$18

0.06

$277

Dominated

  

11

Vitamin A fortification (@80%)

$25

0.10

$244

Dominated

  

12

Vitamin A fortification (@95%)

$29

0.12

$237

Dominated

  

13

Provision of supplementary food and nutritional counselling (SF) (@50%)

$4,039

0.31

$13,189

Dominated

  

14

Provision of supplementary food and nutritional counseling ( (@80%)

$6,462

0.49

$13,187

Dominated

  

15

Provision of supplementary food and nutritional counselling (@95%)

$7,684

0.58

$13,206

Dominated

  

16

Provision of supplementary food and nutritional counselling with growth monitoring (SFGM) (@50%)

$2,491

0.31

$8,133

Dominated

  

17

Provision of supplementary food and nutritional counselling with growth monitoring (@80%)

$3,984

0.49

$8,131

Dominated

  

18

Provision of supplementary food and nutritional counselling with growth monitoring(@95%)

$4,742

0.58

$8,150

Dominated

  

19

Zinc supplementation (@50%)

$47

0.94

$50

Dominated

  

20

Zinc supplementation (@80%)

$72

1.51

$48

Dominated

  

21

Zinc supplementation (@95%)

$86

1.79

$48

Dominated

  

22

Zinc fortification (@50%)

$9

0.47

$19

Dominated

  

23

Zinc fortification (@80%)

$11

0.75

$15

Dominated

  

24

Zinc fortification (@95%)

$12

0.90

$14

$14

  

25

ORT & CM (@50%)

$463

5.51

$84

Dominated

  

26

ORT & CM (@80%)

$1,059

8.82

$120

Dominated

  

27

ORT & CM (@95%)

$1,321

10.47

$126

Dominated

  

28

Vit A. Fort. & Zinc Fort. (@50%)

$29

0.75

$39

Dominated

  

29

Vit A. Fort. & Zinc Fort. (@80%)

$42

1.20

$35

Dominated

  

30

Vit A. Fort. & Zinc Fort. (@95%)

$49

1.42

$35

$70

  

31

Zinc Fort & CM (@50%)

$229

3.27

$70

Dominated

  

32

Zinc Fort & CM (@80%)

$365

5.23

$70

Dominated

  

33

Zinc Fort & CM (@95%)

$470

6.21

$76

Dominated

  

34

Vit. A Suppl. & Zinc Suppl. (@50%)

$214

1.67

$128

Dominated

  

35

Vit. A Suppl. & Zinc Suppl. (@80%)

$344

2.68

$129

Dominated

  

36

Vit. A Suppl. & Zinc Suppl. (@95%)

$451

3.18

$142

Dominated

  

37

Zinc Suppl. & Zinc Fort (@50%)

$89

0.80

$111

Dominated

  

38

Zinc Suppl. & Zinc Fort (@80%)

$141

1.28

$110

Dominated

  

39

Zinc Suppl. & Zinc Fort (@95%)

$191

1.52

$126

Dominated

  

40

Vit. A Fort., Zinc Fort.& ORT (@50%)

$525

3.64

$144

Dominated

  

41

Vit. A Fort., Zinc Fort.& ORT (@80%)

$840

5.82

$144

Dominated

  

42

Vit. A Fort., Zinc Fort.& ORT (@95%)

$1,045

6.91

$151

Dominated

  

43

Vit. A Fort., Zinc Fort. & CM (@50%)

$229

3.59

$64

Dominated

  

44

Vit. A Fort., Zinc Fort. & CM (@80%)

$365

5.68

$64

$74

  

45

Vit. A Fort., Zinc Fort. & CM (@95%)

$470

6.75

$70

$99

  

46

Zinc Fort., ORT & CM (@50%)

$667

6.18

$108

Dominated

  

47

Zinc Fort., ORT & CM (@80%)

$1,068

9.89

$108

Dominated

  

48

Zinc Fort., ORT & CM (@95%)

$1,577

11.74

$134

Dominated

  

49

Zinc Suppl., ORT & CM (@50%)

$513

6.71

 

Dominated

  

50

Zinc Suppl., ORT & CM (@80%)

$1,138

10.74

$106

Dominated

  

51

Zinc Suppl., ORT & CM (@95%)

$1,421

12.75

$111

Dominated

  

52

Vit. A Suppl., Zinc Suppl., & CM (@50%)

$384

4.54

$85

Dominated

  

53

Vit. A Suppl., Zinc Suppl., & CM (@80%)

$617

7.26

$85

Dominated

  

54

Vit. A Suppl., Zinc Suppl., & CM (@95%)

$793

8.62

$92

Dominated

  

55

Vit. A Suppl., Zinc Suppl., & ORT (@50%)

$681

4.58

$149

Dominated

  

56

Vit. A Suppl., Zinc Suppl., & ORT (@80%)

$1,093

7.33

$149

Dominated

  

57

Vit. A Suppl., Zinc Suppl., & ORT (@95%)

$1,370

8.70

$157

Dominated

  

58

Vit. A Suppl., Zinc Suppl., ORT & CM (@50%)

$849

7.51

$113

Dominated

  

59

Vit. A Suppl., Zinc Suppl., ORT & CM (@80%)

$1,363

12.02

$113

Dominated

  

60

Vit. A Suppl., Zinc Suppl., ORT & CM (@95%)

$1,955

14.28

$137

Dominated

  

61

Vit. A Fort., Zinc Fort., ORT & CM (@50%)

$687

6.48

$106

Dominated

  

62

Vit. A Fort., Zinc Fort., ORT & CM (@80%)

$1,099

10.37

$106

Dominated

  

63

Vit. A Fort., Zinc Fort., ORT & CM (@95%)

$1,367

12.32

$111

Dominated

  

64

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@50%)

$243

1.10

$220

Dominated

  

65

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@80%)

$387

1.77

$219

Dominated

  

66

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@95%)

$500

2.10

$238

Dominated

  

67

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@50%)

$3,119

7.57

$412

Dominated

  

68

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@80%)

$5,310

12.11

$439

Dominated

  

69

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@95%)

$6,407

14.38

$446

Dominated

  

70

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@50%)

$3,153

6.52

$484

Dominated

  

71

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@80%)

$5,044

10.42

$484

Dominated

  

72

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@95%)

$6,308

12.38

$510

Dominated

  

73

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@50%)

$413

3.91

$106

Dominated

  

74

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@80%)

$659

6.26

$105

Dominated

  

75

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@95%)

$843

7.43

$113

Dominated

  

76

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@50%)

$878

6.85

$128

Dominated

  

77

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@80%)

$1,405

10.95

$128

Dominated

  

78

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@95%)

$2,004

13.01

$154

Dominated

  

79

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@50%)

$3,343

6.88

$486

Dominated

  

80

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@80%)

$5,349

11.00

$486

Dominated

  

81

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@95%)

$6,699

13.07

$513

Dominated

  

82

Vit A. Fort. & Zinc Fort. (@50%) + Measles immunisation (@50%)

$118

1.46

$81

Dominated

  

83

Vit A. Fort. & Zinc Fort. (@80%) + Measles immunisation (@50%)

$131

1.91

$69

Dominated

  

84

Vit A. Fort. & Zinc Fort. (@95%) + Measles immunisation (@50%)

$138

2.14

$64

Dominated

  

85

Zinc Fort & CM (@50%) + Measles immunisation (@50%)

$318

3.98

$80

Dominated

  

86

Zinc Fort & CM (@80%) + Measles immunisation (@50%)

$453

5.94

$76

Dominated

  

87

Zinc Fort & CM (@95%) + Measles immunisation (@50%)

$558

6.92

$81

Dominated

  

88

Vit. A Suppl. & Zinc Suppl. (@50%) + Measles immunisation (@50%)

$302

2.39

$127

Dominated

  

89

Vit. A Suppl. & Zinc Suppl. (@80%) + Measles immunisation (@50%)

$433

3.39

$128

Dominated

  

90

Vit. A Suppl. & Zinc Suppl. (@95%) + Measles immunisation (@50%)

$539

3.89

$139

Dominated

  

91

Zinc Suppl. & Zinc Fort (@50%) + Measles immunisation (@50%)

$177

1.51

$117

Dominated

  

92

Zinc Suppl. & Zinc Fort (@80%) + Measles immunisation (@50%)

$229

1.99

$115

Dominated

  

93

Zinc Suppl. & Zinc Fort (@95%) + Measles immunisation (@50%)

$279

2.23

$125

Dominated

  

94

Vit. A Fort., Zinc Fort.& ORT (@50%) + Measles immunisation (@50%)

$614

4.35

$141

Dominated

  

95

Vit. A Fort., Zinc Fort.& ORT (@80%) + Measles immunisation (@50%)

$928

6.53

$142

Dominated

  

96

Vit. A Fort., Zinc Fort.& ORT (@95%) + Measles immunisation (@50%)

$1,134

7.63

$149

Dominated

  

97

Vit. A Fort., Zinc Fort. & CM (@50%) + Measles immunisation (@50%)

$318

4.30

$74

Dominated

  

98

Vit. A Fort., Zinc Fort. & CM (@80%) + Measles immunisation (@50%)

$453

6.40

$71

Dominated

  

99

Vit. A Fort., Zinc Fort. & CM (@95%) + Measles immunisation (@50%)

$558

7.46

$75

Dominated

  

100

Zinc Fort., ORT & CM (@50%) + Measles immunisation (@50%)

$756

6.89

$110

Dominated

  

101

Zinc Fort., ORT & CM (@80%) + Measles immunisation (@50%)

$1,157

10.60

$109

Dominated

  

102

Zinc Fort., ORT & CM (@95%) + Measles immunisation (@50%)

$1,665

12.45

$134

Dominated

  

103

Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@50%)

$601

7.42

$81

Dominated

  

104

Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@50%)

$1,227

11.45

$107

Dominated

  

105

Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@50%)

$1,509

13.46

$112

Dominated

  

106

Vit. A Suppl., Zinc Suppl., & CM (@50%) + Measles immunisation (@50%)

$472

5.25

$90

Dominated

  

107

Vit. A Suppl., Zinc Suppl., & CM (@80%) + Measles immunisation (@50%)

$705

7.97

$89

Dominated

  

108

Vit. A Suppl., Zinc Suppl., & CM (@95%) + Measles immunisation (@50%)

$882

9.33

$95

Dominated

  

109

Vit. A Suppl., Zinc Suppl., & ORT (@50%) + Measles immunisation (@50%)

$769

5.29

$145

Dominated

  

110

Vit. A Suppl., Zinc Suppl., & ORT (@80%) + Measles immunisation (@50%)

$1,181

8.04

$147

Dominated

  

111

Vit. A Suppl., Zinc Suppl., & ORT (@95%) + Measles immunisation (@50%)

$1,459

9.41

$155

Dominated

  

112

Vit. A Suppl., Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@50%)

$937

8.23

$114

Dominated

  

113

Vit. A Suppl., Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@50%)

$1,451

12.74

$114

Dominated

  

114

Vit. A Suppl., Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@50%)

$2,043

14.99

$136

Dominated

  

115

Vit. A Fort., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@50%)

$776

7.20

$108

Dominated

  

116

Vit. A Fort., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@50%)

$1,187

11.09

$107

Dominated

  

117

Vit. A Fort., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@50%)

$1,456

13.03

$112

Dominated

  

118

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@50%) + Measles immunisation (@50%)

$331

1.82

$182

Dominated

  

119

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@80%) + Measles immunisation (@50%)

$475

2.48

$192

Dominated

  

120

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@95%) + Measles immunisation (@50%)

$589

2.81

$210

Dominated

  

121

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@50%) + Measles immunisation (@50%)

$3,208

8.28

$387

Dominated

  

122

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@80%) + Measles immunisation (@50%)

$5,398

12.82

$421

Dominated

  

123

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@95%) + Measles immunisation (@50%)

$6,496

15.09

$430

Dominated

  

124

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@50%)

$3,241

7.23

$448

Dominated

  

125

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@50%)

$5,132

11.14

$461

Dominated

  

126

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@50%)

$6,396

13.09

$489

Dominated

  

127

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@50%) + Measles immunisation (@50%)

$501

4.62

$108

Dominated

  

128

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@80%) + Measles immunisation (@50%)

$748

6.97

$107

Dominated

  

129

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@95%) + Measles immunisation (@50%)

$931

8.14

$114

Dominated

  

130

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@50%)

$967

7.56

$128

Dominated

  

131

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@50%)

$1,494

11.67

$128

Dominated

  

132

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@50%)

$2,093

13.72

$153

Dominated

  

133

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@50%)

$3,431

7.59

$452

Dominated

  

134

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@50%)

$5,438

11.72

$464

Dominated

  

135

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@50%)

$6,787

13.78

$493

Dominated

  

136

Vit A. Fort. & Zinc Fort. (@50%) + Measles immunisation (@80%)

$147

1.89

$78

Dominated

  

137

Vit A. Fort. & Zinc Fort. (@80%) + Measles immunisation (@80%)

$160

2.34

$68

Dominated

  

138

Vit A. Fort. & Zinc Fort. (@95%) + Measles immunisation (@80%)

$167

2.56

$65

Dominated

  

139

Zinc Fort & CM (@50%) + Measles immunisation (@80%)

$347

4.41

$79

Dominated

  

140

Zinc Fort & CM (@80%) + Measles immunisation (@80%)

$482

6.37

$76

Dominated

  

141

Zinc Fort & CM (@95%) + Measles immunisation (@80%)

$587

7.35

$80

Dominated

  

142

Vit. A Suppl. & Zinc Suppl. (@50%) + Measles immunisation (@80%)

$331

2.81

$118

Dominated

  

143

Vit. A Suppl. & Zinc Suppl. (@80%) + Measles immunisation (@80%)

$462

3.82

$121

Dominated

  

144

Vit. A Suppl. & Zinc Suppl. (@95%) + Measles immunisation (@80%)

$568

4.32

$132

Dominated

  

145

Zinc Suppl. & Zinc Fort (@50%) + Measles immunisation (@80%)

$206

1.94

$106

Dominated

  

146

Zinc Suppl. & Zinc Fort (@80%) + Measles immunisation (@80%)

$258

2.42

$107

Dominated

  

147

Zinc Suppl. & Zinc Fort (@95%) + Measles immunisation (@80%)

$308

2.65

$116

Dominated

  

148

Vit. A Fort., Zinc Fort.& ORT (@50%) + Measles immunisation (@80%)

$643

4.78

$135

Dominated

  

149

Vit. A Fort., Zinc Fort.& ORT (@80%) + Measles immunisation (@80%)

$957

6.96

$137

Dominated

  

150

Vit. A Fort., Zinc Fort.& ORT (@95%) + Measles immunisation (@80%)

$1,162

8.05

$144

Dominated

  

151

Vit. A Fort., Zinc Fort. & CM (@50%) + Measles immunisation (@80%)

$347

4.73

$73

Dominated

  

152

Vit. A Fort., Zinc Fort. & CM (@80%) + Measles immunisation (@80%)

$482

6.82

$71

Dominated

  

153

Vit. A Fort., Zinc Fort. & CM (@95%) + Measles immunisation (@80%)

$587

7.89

$74

Dominated

  

154

Zinc Fort., ORT & CM (@50%) + Measles immunisation (@80%)

$785

7.32

$107

Dominated

  

155

Zinc Fort., ORT & CM (@80%) + Measles immunisation (@80%)

$1,185

11.03

$108

Dominated

  

156

Zinc Fort., ORT & CM (@95%) + Measles immunisation (@80%)

$1,694

12.88

$132

Dominated

  

157

Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@80%)

$630

7.85

$80

Dominated

  

158

Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@80%)

$1,256

11.88

$106

Dominated

  

159

Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@80%)

$1,538

13.89

$111

Dominated

  

160

Vit. A Suppl., Zinc Suppl., & CM (@50%) + Measles immunisation (@80%)

$501

5.67

$88

Dominated

  

161

Vit. A Suppl., Zinc Suppl., & CM (@80%) + Measles immunisation (@80%)

$734

8.40

$87

Dominated

  

162

Vit. A Suppl., Zinc Suppl., & CM (@95%) + Measles immunisation (@80%)

$911

9.76

$93

Dominated

  

163

Vit. A Suppl., Zinc Suppl., & ORT (@50%) + Measles immunisation (@80%)

$798

5.72

$139

Dominated

  

164

Vit. A Suppl., Zinc Suppl., & ORT (@80%) + Measles immunisation (@80%)

$1,210

8.47

$143

Dominated

  

165

Vit. A Suppl., Zinc Suppl., & ORT (@95%) + Measles immunisation (@80%)

$1,488

9.84

$151

Dominated

  

166

Vit. A Suppl., Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@80%)

$966

8.65

$112

Dominated

  

167

Vit. A Suppl., Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@80%)

$1,480

13.16

$112

Dominated

  

168

Vit. A Suppl., Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@80%)

$2,072

15.42

$134

Dominated

  

169

Vit. A Fort., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@80%)

$805

7.62

$106

Dominated

  

170

Vit. A Fort., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@80%)

$1,216

11.51

$106

Dominated

  

171

Vit. A Fort., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@80%)

$1,484

13.46

$110

Dominated

  

172

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@50%) + Measles immunisation (@80%)

$360

2.24

$161

Dominated

  

173

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@80%) + Measles immunisation (@80%)

$504

2.91

$173

Dominated

  

174

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@95%) + Measles immunisation (@80%)

$618

3.24

$191

Dominated

  

175

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@50%) + Measles immunisation (@80%)

$3,237

8.71

$372

Dominated

  

176

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@80%) + Measles immunisation (@80%)

$5,427

13.25

$410

Dominated

  

177

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@95%) + Measles immunisation (@80%)

$6,524

15.52

$420

Dominated

  

178

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@80%)

$3,270

7.65

$427

Dominated

  

179

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@80%)

$5,161

11.56

$446

Dominated

  

180

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@80%)

$6,425

13.52

$475

Dominated

  

181

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@50%) + Measles immunisation (@80%)

$530

5.05

$105

Dominated

  

182

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@80%) + Measles immunisation (@80%)

$777

7.40

$105

Dominated

  

183

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@95%) + Measles immunisation (@80%)

$960

8.57

$112

Dominated

  

184

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@80%)

$995

7.99

$125

Dominated

  

185

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@80%)

$1,523

12.09

$126

Dominated

  

186

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@80%)

$2,122

14.15

$150

Dominated

  

187

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@80%)

$3,460

8.02

$432

Dominated

  

188

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@80%)

$5,467

12.14

$450

Dominated

  

189

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@80%)

$6,816

14.21

$480

Dominated

  

190

Vit A. Fort. & Zinc Fort. (@50%) + Measles immunisation (@95%)

$168

2.10

$80

Dominated

  

191

Vit A. Fort. & Zinc Fort. (@80%) + Measles immunisation (@95%)

$181

2.55

$71

Dominated

  

192

Vit A. Fort. & Zinc Fort. (@95%) + Measles immunisation (@95%)

$188

2.78

$68

Dominated

  

193

Zinc Fort & CM (@50%) + Measles immunisation (@95%)

$368

4.62

$80

Dominated

  

194

Zinc Fort & CM (@80%) + Measles immunisation (@95%)

$504

6.58

$77

Dominated

  

195

Zinc Fort & CM (@95%) + Measles immunisation (@95%)

$609

7.56

$80

Dominated

  

196

Vit. A Suppl. & Zinc Suppl. (@50%) + Measles immunisation (@95%)

$352

3.03

$116

Dominated

  

197

Vit. A Suppl. & Zinc Suppl. (@80%) + Measles immunisation (@95%)

$483

4.03

$120

Dominated

  

198

Vit. A Suppl. & Zinc Suppl. (@95%) + Measles immunisation (@95%)

$590

4.53

$130

Dominated

  

199

Zinc Suppl. & Zinc Fort (@50%) + Measles immunisation (@95%)

$227

2.15

$106

Dominated

  

200

Zinc Suppl. & Zinc Fort (@80%) + Measles immunisation (@95%)

$279

2.63

$106

Dominated

  

201

Zinc Suppl. & Zinc Fort (@95%) + Measles immunisation (@95%)

$330

2.87

$115

Dominated

  

202

Vit. A Fort., Zinc Fort.& ORT (@50%) + Measles immunisation (@95%)

$664

4.99

$133

Dominated

  

203

Vit. A Fort., Zinc Fort.& ORT (@80%) + Measles immunisation (@95%)

$978

7.17

$136

Dominated

  

204

Vit. A Fort., Zinc Fort.& ORT (@95%) + Measles immunisation (@95%)

$1,184

8.27

$143

Dominated

  

205

Vit. A Fort., Zinc Fort. & CM (@50%) + Measles immunisation (@95%)

$368

4.94

$74

Dominated

  

206

Vit. A Fort., Zinc Fort. & CM (@80%) + Measles immunisation (@95%)

$504

7.04

$72

Dominated

  

207

Vit. A Fort., Zinc Fort. & CM (@95%) + Measles immunisation (@95%)

$609

8.10

$75

$102

  

208

Zinc Fort., ORT & CM (@50%) + Measles immunisation (@95%)

$806

7.53

$107

Dominated

  

209

Zinc Fort., ORT & CM (@80%) + Measles immunisation (@95%)

$1,207

11.24

$107

Dominated

  

210

Zinc Fort., ORT & CM (@95%) + Measles immunisation (@95%)

$1,715

13.09

$131

Dominated

  

211

Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@95%)

$651

8.07

$81

Dominated

  

212

Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@95%)

$1,277

12.09

$106

Dominated

  

213

Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@95%)

$1,560

14.11

$111

$158

  

214

Vit. A Suppl., Zinc Suppl., & CM (@50%) + Measles immunisation (@95%)

$522

5.89

$89

Dominated

  

215

Vit. A Suppl., Zinc Suppl., & CM (@80%) + Measles immunisation (@95%)

$756

8.61

$88

Dominated

  

216

Vit. A Suppl., Zinc Suppl., & CM (@95%) + Measles immunisation (@95%)

$932

9.97

$93

Dominated

  

217

Vit. A Suppl., Zinc Suppl., & ORT (@50%) + Measles immunisation (@95%)

$819

5.93

$138

Dominated

  

218

Vit. A Suppl., Zinc Suppl., & ORT (@80%) + Measles immunisation (@95%)

$1,232

8.68

$142

Dominated

  

219

Vit. A Suppl., Zinc Suppl., & ORT (@95%) + Measles immunisation (@95%)

$1,509

10.06

$150

Dominated

  

220

Vit. A Suppl., Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@95%)

$987

8.87

$111

Dominated

  

221

Vit. A Suppl., Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@95%)

$1,501

13.38

$112

Dominated

  

222

Vit. A Suppl., Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@95%)

$2,094

15.63

$134

$350

  

223

Vit. A Fort., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@95%)

$826

7.84

$105

Dominated

  

224

Vit. A Fort., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@95%)

$1,237

11.73

$106

Dominated

  

225

Vit. A Fort., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@95%)

$1,506

13.67

$110

Dominated

  

226

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@50%) + Measles immunisation (@95%)

$382

2.46

$155

Dominated

  

227

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@80%) + Measles immunisation (@95%)

$525

3.12

$168

Dominated

  

228

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@95%) + Measles immunisation (@95%)

$639

3.45

$185

Dominated

  

229

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@50%) + Measles immunisation (@95%)

$3,258

8.92

$365

Dominated

  

230

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@80%) + Measles immunisation (@95%)

$5,449

13.46

$405

Dominated

  

231

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@95%) + Measles immunisation (@95%)

$6,546

15.73

$416

$44,384

  

232

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@95%)

$3,291

7.87

$418

Dominated

  

233

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@95%)

$5,182

11.78

$440

Dominated

  

234

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@95%)

$6,447

13.73

$469

Dominated

  

235

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@50%) + Measles immunisation (@95%)

$552

5.26

$105

Dominated

  

236

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@80%) + Measles immunisation (@95%)

$798

7.61

$105

Dominated

  

237

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@95%) + Measles immunisation (@95%)

$981

8.78

$112

Dominated

  

238

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@95%)

$1,017

8.20

$124

Dominated

  

239

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@95%)

$1,544

12.31

$125

Dominated

  

240

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@95%)

$2,143

14.36

$149

Dominated

  

241

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@95%)

$3,482

8.23

$423

Dominated

  

242

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@95%)

$5,488

12.36

$444

Dominated

  

243

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@95%)

$6,837

14.42

$474

Dominated

  

 

 

Annex A: [As supplied by authors]

Case management for childhood pneumonia and oral rehydration therapy:

These are the original algorithmic approaches developed by WHO wherein specific actions, e.g. provision of antibiotics for pneumonia (or oral rehydration solution for diarrhea) and /or hospitalization are triggered by the detection of specific signs and symptoms.

Provision of supplementary food during weaning with counselling on nutrition:

One-time intensive counselling is provided to mothers on the appropriate complementary feeding practices and on the importance of continued breast-feeding. In addition, all infants, aged six months to one year, regardless of nutritional status, are provided with ready-to-mix supplementary food, which is collected every two months from a health centre by the caregiver. It was then assumed that each cohort of children exposed to this intervention would continue to reap the benefits subsequently because of the knowledge and attitudes retained by the caregiver.

Provision of supplementary food with nutrition counselling and growth monitoring and promotion (targeted):

All caregivers are given an initial intensive counselling session on appropriate complementary feeding practices and the importance of continued breastfeeding. Caregivers are provided with growth charts and during quarterly visits, the weight of the child is plotted and any deviations from expected weight gain discussed. Solutions are suggested and targets for weight gain are set. In addition, ready-to-mix supplementary food is provided to all children from age six months to one year who are mild to severely underweight.

Vitamin A supplementation:

Oral Vitamin A supplements are provided to all children under five years of age twice a year at a health centre. The dose is 200,000 i.u. for children from their first birthday. For those less than one year of age, the dose is 50-100,000 i.u. Effectiveness of the intervention is adjusted by an assumed adherence of 75%.

Vitamin A fortification:

Fortification of a food staple with Vitamin A (in this case assumed to be sugar), whether locally produced or imported, or whether for industrial or domestic use, is assured through legislation. The amount of Vitamin A required is calculated based on a consideration of the expected sources of Vitamin A and the average per capita intake of sugar in different settings. Intervention includes provision of guidelines for quality control of sugar fortification in the mills, regular visits to mills by inspectors, and regular sampling and testing of sugar taken from mills, markets and homes for Vitamin A content. Samples from homes are taken opportunistically during mass surveys carried out for other purposes. Effectiveness is adjusted using assumptions regarding access to processed food.

Zinc supplementation:

During one of the first immunisations contacts in infancy, the health worker prescribes zinc gluconate or sulfate, 10 mg in solution as part of a routine. Thereafter, the zinc solution is administered by a caregiver at home daily to every child until the child reaches five years of age. Effectiveness of the intervention is adjusted by an assumed adherence of 60% for medications being taken daily.

Zinc fortification:

The intervention has the same characteristics as for Vitamin A fortification except the nutrient added is zinc oxide and the food vehicle is wheat, not sugar. Note that in the absence of documented field experience, the effectiveness of zinc fortification was modelled relative to the effectiveness of supplementation at approximately the level of vitamin a supplementation to fortification.

Measles Immunization:

Single dose measles vaccine injected at the age of nine

months to a child by a professional in a health facility.