Supporting information for Riley et al. (2002) Proc. Natl. Acad. Sci. USA, 10.1073/pnas.162359999
Fig 7.
Regulation of selected genes during TCR stimulation of CD4 T cells without and with CD28 costimulation. CD4 T cells were stimulated with CD3 or CD3/CD28 beads for 2, 8, or 24 h as in Fig. 3D. Flagged are representative T cell cytokines [IL2 (NM_000589), IL-4 (NM_000619), gIFN (NM_000758), colony stimulating factor 2 (granulocyte-macrophage), CSF2, (AF373868), and TNFa (NM_000594)]; T cell activation genes [CD69 (NM_000417), interleukin 2 receptor, alpha (NM_005214) cytotoxic T-lymphocyte-associated protein 4, CTLA4, (NM_005214), and ICOS (AB023135)]; protein biosynthetic genes [WARS, tryptophanyl-tRNA synthetase, (NM_004184), NARS, asparaginyl-tRNA synthetase (NM_004539), AARS, alanyl-tRNA synthetase, (NM_001605), IARS, isoleucine-tRNA synthetase, (NM_002161), MARS, methionine-tRNA synthetase, (NM_004990)]; and tumor suppressor genes [BIN1, bridging integrator 1, (NM_004305); TOB1, transducer of ERBB2, (NM_005749), TSC22, transforming growth factor beta-stimulated protein(NM_006022) and KLF2, Kruppel-like factor (NM_016270)].