|
Table S31: Centromere predictionsa. |
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|
Pf chr |
Pf gene downstream |
RMP gene downstream |
RMP contig downstream |
End of synteny |
Pf gene upstream |
RMP gene upstream |
RMP contig upstream |
Start of synteny |
Distance between
flanking syntenic genes |
Method of linkage |
Size of PCR fragment
(bp) |
RMP chr |
|
1 |
PFA0585w |
PY01445 |
MALPY00384 |
457,239 |
PFA0590w |
NI |
not syntenic |
- |
- |
SLE |
- |
2 |
|
2 |
PFB0490c |
PB000558.01.0 |
Pb.c001904474.
Contig1 |
443,244 |
PFB0495w |
PY05091 |
MALPY01600 |
449,666 |
6,422 |
PCR |
4,000 |
3 |
|
3 |
PFC0610c |
PY02287 |
MALPY00628 |
587,740 |
PFC0615w |
PY07280 |
MALPY02636 |
601,130 |
13,390 |
None |
- |
4 |
|
4 |
PFD0690c |
PY00550 |
MALPY00150 |
641,902 |
PFD0695w |
PY02205 |
MALPY00605 |
659,376 |
17,474 |
None |
- |
7 |
|
5 |
chr5-tRNA-Leu-1 |
tRNA-Leu-1 |
MALPY02997 |
452,699 |
PFE0530w |
PY04900 |
MALPY01520 |
458,119 |
5,420 |
PCR |
4,000 |
11 |
|
6 |
MAL6P1.152 |
PY04637 |
MALPY01429 |
1,151,208 |
MAL6P1.151 |
PY02706 |
MALPY00748 |
1,152,410 |
1,202 |
None |
- |
11 |
|
6b |
MAL6P1.116 |
PY03119 |
MALPY00884 |
526,726 |
MAL6P1.309 |
PY02914 |
MALPY00821 |
528,552 |
1,826 |
None |
- |
1 |
|
7 |
PF07_0050 |
NI |
not syntenic |
411,168 |
MAL7P1.52 |
NI |
not syntenic |
517,160 |
105,992 |
None |
- |
SBP |
|
7b |
MAL7P1.91 |
PY02993 |
MALPY00846 |
708,966 |
MAL7P1.92 |
PY05845 |
MALPY01919 |
714,099 |
5,133 |
None |
- |
6 |
|
8 |
MAL8P1.136 |
PY05152 |
MALPY01625 |
1,020,763 |
PF08_0118 |
PY05558 |
MALPY01784 |
1,023,858 |
3,095 |
None |
- |
12 |
|
9 |
PFI1500w |
PY06205 |
MALPY02081 |
1,240,525 |
PFI1505c |
PY07561 |
MALPY02813 |
1,242,181 |
1,656 |
PCR |
2,200 |
8 |
|
10 |
PF10_0216 |
PY07622 |
MALPY02840 |
934,786 |
PF10_0217 |
PY01659 |
MALPY00449 |
939,652 |
4,866 |
PCR |
3,500 |
5 |
|
11 |
PF11_0226 |
PY06052 |
MALPY02015 |
826,272 |
PF11_0227 |
PY06967 |
MALPY02459 |
831,942 |
5,670 |
PCR |
2,000 |
9 |
|
12 |
PFL1505c |
PY05255 |
MALPY01663 |
1,282,467 |
PFL1510c |
PY05931 |
MALPY01956 |
1,285,021 |
2,554 |
PCR |
3,500 |
14 |
|
13b |
MAL13P1.151 |
PY04447 |
MALPY01358 |
1,200,716 |
PF13_0157 |
PY01467 |
MALPY00394 |
1,205,374 |
4,658 |
PCR |
4,000 |
13 |
|
14 |
PF14_0252 |
PY05795 |
MALPY01896 |
1,068,157 |
PF14_0253 |
PY02120 |
MALPY00583 |
1,075,409 |
7,252 |
PCR |
9,000 |
10 |
|
a Predictions of the location of
centromeres in the genome of P.
falciparum and RMP based on comparison of the synteny blocks. For all
previous centromere predictions (Hall et al. 2002), the flanking P. falciparum genes and their
positions on the chromosome as well as the RMP genes and contigs both up- and
downstream of the centromere are given. b Newly predicted centromeres are shown in bold. Pf
= P. falciparum; chr = chromosome; RMP = rodent malaria parasites; NI
= not identified; SLE = subtelomere linked end; SBP = synteny breakpoint |
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