Supplimental Table 5 Twenty-two of the 88 candidate genes significantly related with MeSH term
@
aRelated MeSH term of down-regulated gene
@Related "Disease" MeSH termNumber of related genesa@Total Score of related genesb@Representative gene symbolc@ Score of representative gened 
@Retinal Degeneration3@1.0427 @PDE6B @1.0000
@Hyperglycinemia, Nonketotic1@0.8560 @NICN1 @0.8560
@Chromosome Deletion4@0.2529 @LARS @0.2459
@Retinitis Pigmentosa2@0.2741 @PDE6B @0.2307
@Breast Neoplasms9@0.2789 @SRA1 @0.1643
@Anemia2@0.1016 @STOM @0.1014
@Infertility, Male2@0.0901 @ARL6IP5 @0.0901
@Lung Neoplasms8@0.1049 @RASSF1 @0.0854
@Carcinoma, Non-Small-Cell Lung5@0.0748 @RASSF1 @0.0722
@Cerebral Amyloid Angiopathy2@0.0693 @CST3 @0.0650
@Mucopolysaccharidosis III1@0.0564 @NAGLU @0.0564
@Glioma4@0.0634 @SEPW1 @0.0547
@Cat Diseases1@0.0546 @PDE6B @0.0546
@aNumber of gene were related with a MeSH terms. bTotal score of all genes related with a MeSH terms. cGene symbol of a gene significantly related with MeSH term (Score>0.05). dScore of a gene significantly related with MeSH term  (Score>0.05).
@@@@@@
b@@@@@
@Related MeSH term of up-regulated gene
@Related "Disease" MeSH termNumber of related genesa@Total Score of related genesb@Representative gene symbolc@ Score of representative gened 
@Lymphoma, Large-Cell, Ki-11@1.0000 @ALK@1.0000
@Thiamine Deficiency1@0.7983 @OGDHL @0.7983
@Carcinoma, Ehrlich Tumor2@0.6492 @OGDHL@0.6492
@Stress3@0.5050 @ERN1 @0.5043
@Neoplasms, Experimental6@0.4520 @STAG1@0.4410
@Genetic Predisposition to Disease9@0.4824 @PADI4@0.4400
@Leukemia, Prolymphocytic2@0.4248 @MTCP1@0.4052
@Amyloidosis3@0.3815 @APCS @0.3616
@Lymphoma, Large-Cell2@0.3186 @ALK @0.3101
@Ataxia Telangiectasia1@0.3038 @MTCP1 @0.3038
@Hemophilia A2@0.2606 @MTCP1 @0.2606
@Lymphoma, Mucosa-Associated Lymphoid Tissue1@0.2346 @BCL10 @0.2346
@Translocation (Genetics)5@0.5186 @MTCP1 @0.2233
@Translocation (Genetics)5@0.5186 @ALK @0.2151
@Lymphoma, T-Cell2@0.1964 @ALK @0.1766
@Breast Neoplasms9@0.2789 @SAFB @0.1643
@Obesity4@0.1476 @BBS4 @0.1471
@Arthritis, Rheumatoid6@0.1510 @PADI4 @0.1467
@Neuroblastoma5@0.1229 @ERN1 @0.1142
@Cystic Fibrosis3@0.1140 @CLCN5 @0.1137
@Mitochondrial Diseases1@0.1128 @DGUOK @0.1128
@Alzheimer Disease6@0.1797 @ERN1 @0.1111
@Hodgkin Disease4@0.1008 @ALK @0.0951
@Kidney Calculi2@0.0927 @CLCN5 @0.0923
@Abnormalities3@0.0557 @HOXD4 @0.0536
@
@aNumber of gene were related with a MeSH terms. bTotal score of all genes related with a MeSH terms. cGene symbol of a gene significantly related with MeSH term (Score>0.05). dScore of a gene significantly related with MeSH term  (Score>0.05).