Supplementary material for Eichmüller et al. (January 9, 2001) Proc. Natl. Acad. Sci. USA, 10.1073/pnas.021386498
Percent identity to the consensus amino acid sequence
se2-1 | 99.9% |
se5-1 | 99.4% |
se20-8 | 98.2% |
se33-2 | 99.0% |
se37-1 | 99.2% |
HOM-TSRCC1-7 | 99.6% |
SCP-1 | 94.9% |
Note: Missing parts in the beginning or end of the sequence are not considered.
Coding:
~ missing amino acid at the beginning or end of the sequence
. gap
blue consensus sequence
red mismatches of se-clones to consensus sequence
pink mismatches of HOM-TSRCC7-1 to consensus sequence
green mismatches of SCP-1 to consensus sequence
1
se2-1 MEKQKPFALF VPPRSSSSQV SAVKPQTLGG DSTFFKSFNK CTEDDFEFPF
se5-1 MEKQKPFALF VPPRSSSSQV SAVKPQTLGG DSTFFKSFNK CTEDDFEFPF
se20-8 MEKQKPFALF VPPRSSSSQV SAVKPQTLGG DSTFFKSFNK CTEDDFEFPF
se33-2 MEKQKPFALF VPPRSSSSQV SAVKPQTLGG DSTFFKSFNK CTEDDFEFPF
se37-1 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~
consensus2-1 MEKQKPFALF VPPRSSSSQV SAVKPQTLGG DSTFFKSFNK CTEDDFEFPF
hom-tsrcc1-7 MEKQKPFALF VPPRSSSSQV SAVKPQTLGG DSTFFKSFNK CTEDDLEFPF
scp-1 MEKQKPFALF VPPRSSSSQV SAVKPQTLGG DSTFFKSFNK CTEDDFEFPF 51
se2-1 AKTNLSKNGE NIDSDPALQK VNFLPVLEQV GNSDCHYQEG LKDSDLENSE
se5-1 AKTNLSKNGE NIDSDPALQK VNFLPVLEQV GNSDCHYQEG LKDSDLENSE
se20-8 AKTNLSKNGE NIDSDPALQK VNFLPVLEQV GNSDCHYQEG LKDSDLENSE
se33-2 AKTNLSKNGE NIDSDPALQK VNFLPVLEQV GNSDCHYQEG LKDSDLENSE
se37-1 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~
consensus2-1 AKTNLSKNGE NIDSDPALQK VNFLPVLEQV GNSDCHYQEG LKDSDLENSE
hom-tsrcc1-7 AKTNLSKNGE NIDSDPALQK VNFLPVLEQV GNSDCHYQEG LKDSDLENSE
scp-1 AKTNLSKNGE NIDSDPALQK VNFLPVLEQV GNSDCHYQEG LKDSDLENSE 101
se2-1 GLSRVYSKLY KEAEKIKKWK VSTEAELRQK ESKLQENRKI IEAQRKAIQE
se5-1 GLSRVYSKLY KEAEKIKKWK VSTEAELRQK ESKLQENRKI IEAQRKAIQE
se20-8 GLSRVYSKLY KEAEKIKKWK VSTEAELRQK ESKLQENRKI IEAQRKAIQE
se33-2 GLSRVYSKLY KEAEKIKKWK VSTEAELRQK ESKLQENRKI IEAQRKAIQE
se37-1 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~
consensus2-1 GLSRVYSKLY KEAEKIKKWK VSTEAELRQK ESKLQENRKI IEAQRKAIQE
hom-tsrcc1-7 GLSRVFSKLY KEAEKIKKWK VSTEAELRQK ESKLQENRKI IEAQRKAIQE
scp-1 GLSRVYSKLY KEAEKIKKWK VSTEAELRQK ESKLQENRKI IEAQRKAIQE 151
se2-1 LQFGNEKVSL KLEEGIQENK DLIKENNATR HLCNLLKETC ARSAEKTKKY
se5-1 LQFGNEKVSL KLEEGIQENK DLIKENNATR HLCNLLKETC ARSAEKTKKY
se20-8 LQFGNEKVSL KLEEGIQENK DLIKENNATR HLCNLLKETC ARSAEKTKKY
se33-2 LQFGNEKVSL KLEEGIQENK DLIKENNATR HLCNLLKETC ARSAEKTKKY
se37-1 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~
consensus2-1 LQFGNEKVSL KLEEGIQENK DLIKENNATR HLCNLLKETC ARSAEKTKKY
hom-tsrcc1-7 LQFGNEKVSL KLEEGIQENK DLIKENNATR HLCNLLKETC ARSAEKTKKY
scp-1 LQCGNEKVSL TLEEGIQDNK DLIKENNATR HLCNLLKETC ARSAEKTKKY 201
se2-1 EYEREETRQV YMDLNNNIEK MITAFEELRV QAENSRLEMH FKLKEDYEKI
se5-1 EYEREETRQV YMDLNNNIEK MITAFEELRV QAENSRLEMH FKLKEDYEKI
se20-8 EYEREETRQV YMDLNNNIEK MITAFEELRV QAENSRLEMH FKLKEDYEKI
se33-2 EYEREETRQV YMDLNNNIEK MITAFEELRV QAENSRLEMH FKLKEDYEKI
se37-1 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~
consensus2-1 EYEREETRQV YMDLNNNIEK MITAFEELRV QAENSRLEMH FKLKEDYEKI
hom-tsrcc1-7 EYEREETRQV YMDLNNNIEK MITAHGELRV QAENSRLEMH FKLKEDYEKI
scp-1 EYEREETRQV YMDLNSNIEK MITAFEELRV QAENSRLEMH FKLKEDYEKI 251
se2-1 QHLEQEYKKE INDKEKQVSL LLIQITEKEN KMKDLTFLLE ESRDKVNQLE
se5-1 QHLEQEYKKE INDKEKQVSL LLIQITEKEN KMKDLTFLLE ESRDKVNQLE
se20-8 QHLEQEYKKE INDKEKQVSL LLIQITEKEN KMKDLTFLLE ESRDKVNQLE
se33-2 QHLEQEYKKE INDK...VSL LLIQITEKEN KMKDLTFLLE ESRDKVNQLE
se37-1 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~KDLTFLLE ESRDKVNQLE
consensus2-1 QHLEQEYKKE INDKEKQVSL LLIQITEKEN KMKDLTFLLE ESRDKVNQLE
hom-tsrcc1-7 QHLEQEYKKE INDKEKQVSL LLIQITEKEN KMKDLTFLLE ESRDKVNQLE
scp-1 QHLEQEYKKE INDKEKQVSL LLIQITEKEN KMKDLTFLLE ESRDKVNQLE 301
se2-1 EKTKLQSENL KQSIEKQHHL TKELEDIKVS LQRSVSTQKA LEEDLQIATK
se5-1 EKTKLQSENL KQSIEKQHHL TKELEDIKVS LQRSVSTQKA LEEDLQIATK
se20-8 EKTKLQSENL KQSIEKQHHL TKELEDIKVS LQRSVSTQKA LEEDLQIATK
se33-2 EKTKLQSENL KQSIEKQHHL TKELEDIKVS LQRSVSTQKA LEEDLQIATK
se37-1 EKTKLQSENL KQSIEKQHHL TKELEDIKVS LQRSVSTQKA LEEDLQIATK
consensus2-1 EKTKLQSENL KQSIEKQHHL TKELEDIKVS LQRSVSTQKA LEEDLQIATK
hom-tsrcc1-7 EKTKLQSENL KQSIEKQHHL TKELEDIKVS LQRSVSTQKA LEEDLQIATK
scp-1 EKTKLQSENL KQSIEKQHHL TKELEDIKVS LQRSVSTQKA LEEDLQIATN 351
se2-1 TICQLTEEKE TQMEESNKAR AAHSFVVTEF ETTVCSLEEL LRTEQQRLEK
se5-1 TICQLTEEKE TQMEESNKAR AAHSFVVTEF ETTVCSLEEL LRTEQQRLEK
se20-8 TICQLTEEKE TQMEESNKAR AAHSFVVTEF ETTVCSLEEL LRTEQQRLEK
se33-2 TICQLTEEKE TQMEESNKAR AAHSFVVTEF ETTVCSLEEL LRTEQQRLEK
se37-1 TICQLTEEKE TQMEESNKAR AAHSFVVTEF ETTVCSLEEL LRTEQQRLEK
consensus2-1 TICQLTEEKE TQMEESNKAR AAHSFVVTEF ETTVCSLEEL LRTEQQRLEK
hom-tsrcc1-7 TICQLTEEKE TQMEESNKAR AAHSFVVTEF ETTVCSLEEL LRTEQQRLEK
scp-1 TICQLTEEKD TQMEESNKAR AAHSFVVTEF ETTVCSLEEL LRTEQQRLEN 401
se2-1 NEDQLKILTM ELQKKSSELE EMTKLTNNKE VELEELKKVL GEKETLLYEN
se5-1 NEDQLKILTM ELQKKSSELE EMTKLTNNKE VELEELKKVL GEKETLLYEN
se20-8 NEDQLKILTM ELQKKSSELE EMTKLTNNKE VELEELKKVL GEKETLLYEN
se33-2 NEDQLKILTM ELQKKSSELE EMTKLTNNKE VELEELKKVL GEKETLLYEN
se37-1 NEDQLKILTM ELQKKSSELE EMTKLTNNKE VELEELKKVL GEKETLLYEN
consensus2-1 NEDQLKILTM ELQKKSSELE EMTKLTNNKE VELEELKKVL GEKETLLYEN
hom-tsrcc1-7 NEDQLKILTM ELQKKSSELE EMTKLTNNKE VELEELKKVL GEKETLLYEN
scp-1 YEDQLIILTM ELQKTSSELE EMTKLTNNKE VELEELKKVL GEKETLLYDN 451
se2-1 KQFEKIAEEL KGTEQELIGL LQAREKEVHD LEIQLTAITT SEQYYSKEVK
se5-1 KQFEKIAEEL KGTEQELIGL LQAREKEVHD LEIQLTAITT SEQYYSKEVK
se20-8 KQFEKIAEEL KGTEQELIGL LQAREKEVHD LEIQLTAITT SEQYYSKEVK
se33-2 KQFEKIAEEL KGTEQELIGL LQAREKEVHD LEIQLTAITT SEQYYSKEVK
se37-1 KQFEKIAEEL KGTEQELIGL LQAREKEVHD LEIQLTAITT SEQYYSKEVK
consensus2-1 KQFEKIAEEL KGTEQELIGL LQAREKEVHD LEIQLTAITT SEQYYSKEVK
hom-tsrcc1-7 KQFEKIAEEL KGTEQELIGL LQAREKEVHD LEIQLTAITT SEQYYSKEVK
scp-1 KQFEKIAEEL KGTEQELIGL LQAREKEVHD LEYSYC.HYH KWTVLPKRGQ 501
se2-1 DLKTELENEK LKNTELTSHC NKLSLENKEL TQETSDMTLE LKNQQEDINN
se5-1 DLKTELENEK LKNTELTSHC NKLSLENKEL TQETSDMTLE LKNQQEDINN
se20-8 DLKTELENEK LKNTELTSHC NKLSLENKEL TQETSDMTLE LKNQQEDINN
se33-2 DLKTELENEK LKNTELTSHC NKLSLENKEL TQETSDMTLE LKNQQEDINN
se37-1 DLKTELENEK LKNTELTSHC NKLSLENKEL TQETSDMTLE LKNQQEDINN
consensus2-1 DLKTELENEK LKNTELTSHC NKLSLENKEL TQETSDMTLE LKNQQEDINN
hom-tsrcc1-7 DLKTELENEK LKNTELTSHC NKLSLENKEL TQETSDMTLE LKNQQEDINN
scp-1 RPKLSSKRE. LKNTEYFTL. QQASPPPNEL TQETSDMTLE LKNQQEDIIN 551
se2-1 NKKQEERMLK QIENLQETET QLRNELEYVR EELKQKRDEV KCKLDKSEEN
se5-1 NKKQEERMLK QIENLQETET QLRNELEYVR EELKQKRDEV KCKLDKSEEN
se20-8 NKKQEERMLK QIENLQETET QLRNELEYVR EELKQKRDEV KCKLDKSEEN
se33-2 NKKQEERMLK QIENLQETET QLRNELEYVR EELKQKRDEV KCKLDKSEEN
se37-1 NKKQEERMLK QIENLQETET QLRNELEYVR EELKQKRDEV KCKLDKSEEN
consensus2-1 NKKQEERMLK QIENLQETET QLRNELEYVR EELKQKRDEV KCKLDKSEEN
hom-tsrcc1-7 NKKQEERMLK QIENLQETET QLRNELEYVR EELKQKRDEV KCKLDKSEEN
scp-1 NKKQEERMLT QIENLQETET QLRNELEYVR EELKQKRDEV KCKLDKSEEN 601
se2-1 CNNLRKQVEN KNKYIEELQQ ENKALKKKGT AESKQLNVYE IKVNKLELEL
se5-1 CNNLRKQVEN KNKYIEELQQ ENKALKKKGT AESKQLNVYE IKVNKLELEL
se20-8 CNNLRKQVEN KNKYIEELQQ ENKALKKKGT AESKQLNVYE IKVNKLELEL
se33-2 CNNLRKQVEN KNKYIEELQQ ENKALKKKGT AESKQLNVYE IKVNKLELEL
se37-1 CNNLRKQVEN KNKYIEELQQ ENKALKKKGT AESKQLNVYE IKVNKLELEL
consensus2-1 CNNLRKQVEN KNKYIEELQQ ENKALKKKGT AESKQLNVYE IKVNKLELEL
hom-tsrcc1-7 CNNLRKQVEN KNKYIEELQQ ENKALKKKGT AESKQLNVYE IKVNKLELEL
scp-1 CNNLRKQVEN KNKYIEELQQ ENKALKKKGT AESKQLNVYE IKVNKLELEL 651
se2-1 ESAKQKFGEI TDTYQKEIED KKISEENLLE EVEKAKVIAD EAVKLQKEID
se5-1 ESAKQKFGEI TDTYQKEIED KKISEENLLE EVEKAKVIAD EAVKLQKEID
se20-8 ESAKQKFGEI TDTYQKEIED KKISEENLLE EVEKAKVIAD EAVKLQKEID
se33-2 ESAKQKFGEI TDTYQKEIED KKISEENLLE EVEKAKVIAD EAVKLQKEID
se37-1 ESAKQKFGEI TDTYQKEIED KKISEENLLE EVEKAKVIAD EAVKLQKEID
consensus2-1 ESAKQKFGEI TDTYQKEIED KKISEENLLE EVEKAKVIAD EAVKLQKEID
hom-tsrcc1-7 ESAKQKFGEI TDTYQKEIED KKISEENLLE EVEKAKVIAD EAVKLQKEID
scp-1 ESAKQKFGEI TDTYQKEIED KKISEENLLE EVEKAKVIAD EAVKLQKEID 701
se2-1 KRCQHKIAEM VALMEKHKHQ YDKIIEERDS ELGLYKSKEQ EQSSLRASLE
se5-1 KRCQHKIAEM VALMEKHKHQ YDKIIEERDS ELGLYKSKEQ EQSSLRASLE
se20-8 KRCQHKIAEM VALMEKHKHQ YDKIIEERDS ELGLYKSKEQ EQSSLRASLE
se33-2 KRCQHKIAEM VALMEKHKHQ YDKIIEERDS ELGLYKSKEQ EQSSLRASLE
se37-1 KRCQHKIAEM VALMEKHKHQ YDKIIEERDS ELGLYKSKEQ EQSSLRASLE
consensus2-1 KRCQHKIAEM VALMEKHKHQ YDKIIEERDS ELGLYKSKEQ EQSSLRASLE
hom-tsrcc1-7 KRCQHKIAEM VALMEKHKHQ YDKIIEERDS ELGLYKSKEQ EQSSLRASLE
scp-1 KRCQHKIAEM VALMEKHKHQ YDKIIEERDS ELGLYKSKEQ EQSSLRASLE 751
se2-1 IELSNLKAEL LSVKKQLEIE REEKEKLKRE AKENTATLKE KKKKK~~~~~
se5-1 IELSNLKAEL LSVKKQLEIE REEKEKLKRE AKENTATLKE KKKKKKKKK~
se20-8 IELSNLKAEL LSVKKQLEIE REEKEKLKRE AKENTATLKE KKDKKTQTFL
se33-2 IELSNLKAEL LSVKKQLEIE REEKEKLKRE AKENTATLKE KKKKKKKKKK
se37-1 IELSNLKAEL LSVKKQLEIE REEKEKLKKK KKK~~~~~~~ ~~~~~~~~~~
consensus2-1 IELSNLKAEL LSVKKQLEIE REEKEKLKRE AKENTATLKE KKDKKTQTFL
hom-tsrcc1-7 IELSNLKAEL LSVKKQLEIE REEKEKLKRE AKENTATLKE KKDKKTQTFL
scp-1 IELSNLKAEL LSVKKQLEIE REEKEKLKRE AKENTATLKE KKDKKTQTFL 801
se2-1 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~
se5-1 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~
se20-8 LETPEIYWKL DSKAVPSQTV SRNFTSVDHG ISKDKRDYLW TSAKNTLSTP
se33-2 KK~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~
se37-1 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~
consensus2-1 LETPEIYWKL DSKAVPSQTV SRNFTSVDHG ISKDKRDYLW TSAKNTLSTP
hom-tsrcc1-7 LETPEIYWKL DSKAVPSQTV SRNFTSVDHG ISKDKRDYLW TSAKNTLSTP
scp-1 LETPDIYWKL DSKAVPSQTV SRNFTSVDHG ISKDKRDYLW TSAKNTLSTP 851
se2-1 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~
se5-1 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~
se20-8 LPKAYTVKTP TKPKLQQREN LNIPIEESKK KKKKKKKKKK KKKKKKKK~~
se33-2 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~
se37-1 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~
consensus2-1 LPKAYTVKTP TKPKLQQREN LNIPIEESKK KRKMAFEFDI NSDSSETTDL
hom-tsrcc1-7 LPKAYTVKTP TKPKLQQREN LNIPIEESKK KRKMAFEFDI NSDSSETTDL
scp-1 LPKAYTVKTP TKPKLQQREN LNIPIEESKK KRKMAFEFDI NSDSSETTDL 901
se2-1 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~
se5-1 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~
se20-8 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~
se33-2 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~
se37-1 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~
consensus2-1 LSMVSEEETL KTLYRNNNPP ASHLCVKTPK KAPSSLTTPG PTLKFGAIRK
hom-tsrcc1-7 LSMVSEEETL KTLYRNNNPP ASHLCVKTPK KAPSSLTTPG PTLKFGAIRK
scp-1 LSMVSEEETL KTLYRNNNPP ASHLCVKTPK KAPSSLTTPG STLKFGAIRK 951
se2-1 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~
se5-1 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~
se20-8 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~
se33-2 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~
se37-1 ~~~~~~~~~~ ~~~~~~~~~~ ~~~~~~~~~~ ~
consensus2-1 MREDRWAVIA KMDRKKKLKE AEKLFV~~~~ ~
hom-tsrcc1-7 MREDRWAVIA KMDRKKKLKE AEKLFV~~~~ ~
scp-1 MREDRWAVIA KMDRKKKLKE AEKLFV~~~~ ~