Supporting Figure

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Supporting Figure 6

Fig. 6. Sequence analysis of CiPhox2. (A) Alignment of the homeodomains of murine (1, 2), human (3, 4), and Xenopus (5) Phox2a and Phox2b; amphioxus (Branchiostoma floridae) Phox2 (J.-F.B., unpublished data); CiPhox2; and Caenorhabditis elegans CEH-17 (6) with the corresponding percentage of identity with murine Phox2a/b. (B) Genomic locus of CiPhox2 showing phylogenetic footprints with CsPhox2 [displayed according to the VISTA program (7)], indicative of exons and putative regulatory regions in upstream sequences and introns. The fragment used as promoter in this study is shown in green.

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