Supporting information for Welsh et al. (2003) Proc. Natl. Acad. Sci. USA, 10.1073/pnas.0530278100
Fig. 6.
Expression of candidate lung cancer markers in an expanded set of normal and tumor lung tissue samples. The expression levels of lung cancer candidate genes (derived from each group of candidates; GO annotation and sequence-positive; GO annotation-positive only and sequence-positive only; Table 1) was determined in normal lung, lung adenocarcinomas, small cell undifferentiated carcinomas, squamous carcinomas, and carcinoids (1). Data from the study (available at http://research.dfci.harvard.edu/meyersonlab/lungca/data.html) were downloaded and output in TreeView (2). Note the high levels of expression of GRP in carcinoids and small cell lung carcinoma, and the near-uniform overexpression of maspin in squamous carcinomas.1. Bhattacharjee, A., Richards, W. G., Staunton, J., Li, C., Monti, S., Vasa, P., Ladd, C., Beheshti, J., Bueno, R., Gillette, M., et al. (2001) Proc. Natl. Acad. Sci. USA 98, 13790–13795.
2. Eisen, M. B., Spellman, P. T., Brown, P. O. & Botstein, D. (1998) Proc. Natl. Acad. Sci. USA 95, 14863–14868.