Supporting information for Hinds et al. (2003) Proc. Natl. Acad. Sci. USA, 10.1073/pnas.0430202100
Fig. 5.
Cell morphology and density are normal in the hippocampal CA3 region of CA3 α-calcium/calmodulin-dependent protein kinase II (CaMKII) knockout (KO) mice. Sagittal sections from 4-mo-old floxed (a) and CA3 α-CaMKII KO (b) mice were fixed and hybridized with an α-CaMKII-specific oligonucleotide probe and were counterstained with hematoxylin. High-magnification bright-field images of the CA3 hippocampal regions demonstrate that CA3 pyramidal cell bodies are intact, without obvious structural abnormalities, in CA3 α-CaMKII KO mice. Dark grains reflect the presence of α-CaMKII mRNA. Note the relative absence of dark grains in the CA3 region of the CA3 α-CaMKII KO hippocampal section (b).