Supporting information for Teismann et al. (2003) Proc. Natl. Acad. Sci. USA, 10.1073/pnas.0837397100

 

Table 3. MPP+ levels in striatum 90 min after MPTP

Mice

MPP+, m g/g

Ptgs2

+/+ mice

10.6 ± 0.5

Ptgs2

–/– mice

15.2 ± 1.7*

Ptgs2

+/+ mice + JNK inhibitor

10.6 ± 0.7

Ptgs2

–/– mice + JNK inhibitor

15.7 ± 1.4*

Regular (p.o. treated)

 

Vehicle

13.8 ± 1.5

Rofecoxib 25 mg/kg

15.5 ± 2.6

Values are means ± SEM for five to eight mice per group. Groups were compared with the Newman–Keuls posthoc test.

*P < 0.05 compared to Ptgs2+/+ mice and to Ptgs2+/+ mice + JNK inhibitor.