Supporting information for Cui et al. (2003) Proc. Natl. Acad. Sci. USA, 10.1073/pnas.1031601100
Fig. 6.
Histologic appearance of S180 tumor cells in i.p. implants in sensitive and resistant mice. S180 cells (2 ´ 10e7) injected i.p. 16 days before necropsy generated widespread ascites and peritoneal implants in WT BALB/c mice, as typified by the metastatic implant near the renal capsule (A). On the other hand, while a similarly injected SR/CR mouse failed to develop ascites cancers, a few small nodules attached to the peritoneal surface were noted and dissected for histology. (B) These nodules were composed of small numbers of swollen cancer cells (arrows) surrounded by a dense fibroblastic proliferation (desmoplasia) (arrowheads).