Supplementary material for Lee et al., Proc. Natl. Acad. Sci. USA, 10.1073/pnas.140082197

Table 6.

 Nitrogen kinetics in ASS and ASL heterozygotes receiving 0.4 g protein/kg per day

Subject

Diagnosis

Urea flux, µmol/kg per h

Glutamine flux, µmol/kg per h

15

N-urea/15N-glutamine

30011

ASL hetero

104

401

0.475

30012

ASL hetero

86

391

0.465

30013

ASL hetero

86

374

0.255

30021

ASL hetero

124

328

0.211

Mean

 

100

373

0.351

SD

 

15

28

0.119

20042

ASD hetero

72

240

0.196

20022

ASD hetero

76

237

0.236

20051

ASD hetero

129

307

0.258

20041

ASD hetero

158

346

0.197

Mean

 

108

282

0.222

SD

 

36

46

0.026

ASL hetero, argininosuccinic aciduria carrier; ASD hetero, citrullinemia carrier.