Supplementary material for Dym et al. (2000) Proc. Natl. Acad. Sci. USA 97 (17), 9413-9418.
Figure 5 (Adobe PDF)Fig. 5.
Multiple alignment of representative sequences from the family of FAD-dependent proteins. Strongly conserved residues are depicted in black, and the less strongly conserved are in gray. Proteins: DLD_ECOL, D-LDH from E. coli; LDHD_HAEI, D-LDH from Haemophilus influenzae; ADAS_CAVP, Alkyldihydroxyacetonephosphate synthase from Cavia porcellus; AIP2_YEAS, Actin-interacting protein 2 from Saccharomyces cerevisiae; GLCD_ECOL, Glycolate oxidase subunit from E. coli; YE11_YEAST, 55.2 KD protein in hxt8 5' region from S. cerevisiae; DLD1_YEAS, D-LDH from S. cerevisiae; YDIJ_ECOL, Hypothetical 113.2 kDa protein of E. coli.; DLD1_KLUL, D-LDH from Kluyveromyces lactis; YGCU_ECOL, Hypothetical 23.3 kDa protein of E. coli.; YDIJ_HAEI, Hypothetical protein hi1163 from H. influenzae; VAOX_PENS, Vanillyl alcohol oxidase from Penicillium simplicissimum; FAS5_RHOF, Hypothetical 47.9 kDa oxidoreductase from Rhodococcus fascians; HDNO_ARTOX, 6-Hydroxy-D-nicotine oxidase from Arthrobacter oxidans; GGLO_RAT, L-Glunolactone oxidase from Rattus norvegicus; MCRA_STRL, Mitomycine radical oxidase from Streptomyces lavendulae; ALO_YEAST, D-Arabinono-1,4-lactone oxidase from S. cerevisiae; DIMH_CAEE, Diminuto-like protein from C. elegans; GLCE_ECOL, Glycolate oxidase subunit glce from E. coli; MURB_BASCU, UDP-N-Acetylenolpyruvoylglucosamine red from Bacillus subtilis; Gi4808508, p-Cresol methylhydroxylase from Pseudomonas putida. The sequences were created with the program CLUSTALW [Kraulis, P. J. (1991) J. Appl. Crystallogr. 24, 946-950], and the figure was created by using the program JalView [Bacon, D. J. & Anderson, W. F. (1988) J. Mol. Graphics. 6, 219-220].