Supplementary material for Gonzalez et al. (1999) Proc. Natl. Acad. Sci. USA 96 (21), 12004-12009.

Table 2.

 The CCR5-927T polymorphism is not in complete disequilibrium with CCR2-64I, whereas the CCR2-64I polymorphism is in nearly complete linkage disequilibrium with CCR5-927T

 

CCR5-927

C/C

C/T

T/T

CCR2-64V/V
CCR2-64V/I
CCR2-64I/I

851
  5
  0

 49
217
  0

 1
 7
21

Data are from 1,151 individuals from the WHMC cohort. Of the 324 alleles that carry a CCR5-927T polymorphism, 266 also contain the CCR2-64I polyrmorphism, i.e., 18% of CCR5-927T alleles are not in linkage disequilibrium with CCR2-64I (HHF*1 allele). Of the 271 alleles that carry a CCR2-64I polymorphism, 266 alleles also contain the CCR5-927T polymorphism, i.e., 98% of CCR2-64I alleles are in linkage disequilibrium with CCR5-927T.