From the Cover: Preventing ventricular fibrillation by flattening cardiac restitution -- Data Supplement - Supplemental Movie 2 -- Proceedings of the National Academy of Sciences

Supplementary material for Garfinkel et al., Proc. Natl. Acad. Sci. USA, 10.1073/pnas.090492697

QuickTime Video Movie 2.
Conversion of VF to ventricular tachycardia (VT). The drug bretylium tends to flatten cardiac restitution curves (see main paper). When bretylium was added to the perfusate, it dramatically prevented the induction of VF, and it also converted existing VF either to VT or to quiescent excitable tissue. Shown here is an episode of stable VT, converted from VF by the drug. Image properties are the same as those for VF. Note the single spiral wave rotating stably and periodically in the tissue.