Melatonin suppresses macrophage cyclooxygenase-2 and inducible nitric oxide synthase expression by inhibiting p52 acetylation and binding -- Deng et al. 108 (2): 518 Data Supplement - Supplemental materials for: Deng et al -- Blood

Melatonin suppresses macrophage cyclooxygenase-2 and inducible nitric oxide synthase expression by inhibiting p52 acetylation and binding
Blood Deng et al. 108: 518

Supplemental materials for: Deng et al

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Figure S1. Inhibition of NF-κB and other transactivator DNA binding (PDF, 143 KB) -
The experimental protocols for the supplemental figures are identical to those described in Fig. 3. Binding of transactivators to iNOS promoter probe, COX-2 promoter probe and B probe were performed concurrently with p52 DNA binding shown in Fig. 3. A and B. A representative figure showing binding of multiple transactivators to iNOS and COX-2 promoter probes, respectively. C. Transactivator protein levels in the nuclear extracts of cells treated according to procedures described above and in Fig. 3.