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Video 1
MEFs move using an elongated mode of motility in 3D matrix. Corresponds to Fig. 1 A. Time-lapse DIC light microscopy of MEFs within the 3D Matrigel network. Images of cells plated into a thick layer of Matrigel in which a gradient of serum growth factors was established. Moving wt MEFs maintain a spindle-shaped elongated morphology and generate extensions.