Fig. 5. The degenerative eye phenotype of the Drosophila models for polyglutamine disease is not improved in revertant fly for the DSec61α mutant. Light microscopic (A-D) and semithin section images (E-H) of the compound eyes are shown (day 30 after eclosion). The following genotypes are shown: w; GMR-GAL4/+ (A and E), w; GMR-GAL4/+; UAS-MJD(M)/+ (B and F), w; GMR-GAL4 DSec61α^P560/+; UAS-MJD(M)/+ (C and G), and w; GMR-GAL4 DSec61α^P560ex25/+; UAS-MJD(M)/+ (D and H). DSec61α^P560ex25 is one of revertants for original P560 P element insertion line.(Magnifications: ´63, A-D; ´100, E-H.)