Impaired selection of invariant natural killer T cells in diverse mouse models of glycosphingolipid lysosomal storage diseases -- Data Supplement - JEM--Gadola et al. -- The Journal of Experimental Medicine

[HELP with High Resolution Image Viewing]

Figure S1. The percentages and numbers of iNKT cells are reduced in the majority of mouse models of GSL storage disorders tested. Percentages of total lymphocytes (A) and total cell numbers (B) were calculated for iNKT cells in the spleen and thymus of Sandhoff, GM1 gangliosidosis, NPC1, and Fabry mice compared with controls. Data represent the mean ± SE (n = 3-6 mice/group). Statistical significance between GSL storage disease and controls using the t test is indicated. *, P 0.05.