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Figure S3. CyP inhibits the binding of LPS-AF488 to monocytes. Mean fluorescence intensities (MFIs) of monocytes pulsed with 0.25 µg/ml LPS-AF488 in the absence or presence of increasing concentrations of CyP (from 0.25 to 250 µg/ml) were determined from data shown in Fig. 3 C. Percentages of maximal MFIs (obtained in the absence of CyP) are entered in the y axis. The ratio of CyP and LPS-AF488 concentrations is plotted in the x axis. EC50 and R squared values calculated on a sigmoidal dose-response (variable slope) curve are indicated.