Differential natural killer cell mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes -- Data Supplement - JEM--Alter et al. -- The Journal of Experimental Medicine

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Figure S1. NK cells persist during the 14-d viral inhibition assay and are highly activated. (A) The graph represents the absolute number of NK cells in the co-cultures with autologous infected CD4⁺ T cells at a ratio of 10:1 over the course of the 14-d assay (n = 3). Error bars represent the SD. (B) Histograms depict changes in the expression of CD56, CD16, KIR, CD161, NKp46, and NKG2D on the surface of non-NK cells (dashed line) and on NK cells at days 0 (shaded), 7 (gray line), and 14 (black line) in a representative individual. (C) The dot plot shows the MFI of these markers on NK cell populations in six individuals over the 14-d period. Horizontal bars represent the mean. *, P < 0.001.