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Video 2 (856 K)
Effect^{of Cdc42N17 onresponse to a uniform concentrationof fMLP.Video microscopy of a HL-60 cell expressing PH-Akt-GFP andCdc42N17.Exposedattime zero to fMLP (100 nM), the cell accumulatesPH-Akt-GFP atthe membrane, appearsto form one pseudopod, andthenshiftsitspseudopodfrom place to place onthe cell surface atintervalsof 2-3 min.Imageswere takenevery 15 sandare displayedat2 frames/s.}