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Figure S4.^{Phylogenetic analysisof LIS1 proteins.Pac1 iscomparedwith other LIS1 proteinsina dendrogram drawnby TreeView using sequencesalignedby ClustalW (Thompson, J.D., D.G.Higgins, andT.J.Gibson.1994.Nucleic Acids Res.22:4673-4680).Other WD40 repeat-containing proteins, such ascytoplasmic dyneinintermediate chain, are includedto documentthe specific clustering of LIS1 family proteins(coloredinred).Numbersatthe nodesrepresentbootstrapping values(% of 1,000 trials).CDLC, cytoplasmic dyneinlightchain; CDIC, cytoplasmic dyneinintermediate chain.}