[View Larger Version of this Image]

Figure S2.^{Entry kineticsof MBP issimilar to dextransduring phase I.(A) Oocyte injectedwith Alexa 488 MBP andTRITC 160-kDdextran(notdepicted) undergoing maturation.Bar, 25 &microm.Time, mm:ss.0:00, startof 160-kDentry.(B) Quantitationof meannuclear fluorescence, normalizedfrom minimum to maximum values.(C) Calculated(see Supplemental text) fluxesof MBP into the nucleus.Solidline representsa running average of three data points.}