Video 6 (620 KB)
MCF-7 cells transfected with Endo180 with uPA gradient applied. Cells display increased protrusion formation and translocate in the direction of the uPA gradient. Video shows cells on a Matrigel substratum with any chemoattractant source applied at the top of the video and are comprised of 10-min interval frames over a 5-h period of time.