Online Supplement B. EASE results.
Different in Pregnant, not in Normal mice
Gene Symbol | Gene identifiers | GO Biological Process | Gene Name | KEGG_Pathway | Summary |
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Pigr | 5284 | ESTABLISHMENT OF LOCALIZATION;ESTABLISHMENT OF PROTEIN LOCALIZATION;LOCALIZATION;PHYSIOLOGICAL PROCESS;PROTEIN LOCALIZATION;PROTEIN SECRETION;SECRETION | HEPATOCELLULAR CARCINOMA ASSOCIATED PROTEIN TB6;HEPATOCELLULAR CARCINOMA-ASSOCIATED PROTEIN TB6;HYPOTHETICAL PROTEIN DKFZP686I21225;PIGR;POLY-IG RECEPTOR;POLYMERIC IMMUNOGLOBULIN RECEPTOR;POLYMERIC IMMUNOGLOBULIN RECEPTOR (FRAGMENT);POLYMERIC-IMMUNOGLOBULIN RECEPTOR PRECURSOR;POLYMERIC-IMMUNOGLOBULIN RECEPTOR PRECURSOR (POLY-IG RECEPTOR) (PIGR) [CONTAINS: SECRETORY COMPONENT];RECEPTOR;SECRETORY COMPONENT PRECURSOR [VALIDATED] ALT_NAMES:POLY-IG RECEPTOR; POLYMERIC IMMUNOGLOBULIN RECEPTOR CONTAINS:FREE SECRETORY COMPONENT; TRANSMEMBRANE SECRETORY COMPONENT |
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Lcn2 | 3934 | CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;ESTABLISHMENT OF LOCALIZATION;LOCALIZATION;PHYSIOLOGICAL PROCESS;TRANSPORT | 25 KDA ALPHA-2-MICROGLOBULIN-RELATED SUBUNIT OF MMP-9;LCN2 PROTEIN;LCN2 PROTEIN (FRAGMENT);LIPOCALIN 2;LIPOCALIN 2 (ONCOGENE 24P3);LIPOCALIN-2;NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN PRECURSOR;NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN PRECURSOR (NGAL) (P25) (25 KDA ALPHA-2-MICROGLOBULIN-RELATED SUBUNIT OF MMP-9) (LIPOCALIN-2) (ONCOGENE 24P3);NGAL;ONCOGENE 24P3;P25 |
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Gm1960 |
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Ubtf | 7343 | CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;METABOLISM;NUCLEOBASE, NUCLEOSIDE, NUCLEOTIDE AND NUCLEIC ACID METABOLISM;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;REGULATION OF BIOLOGICAL PROCESS;REGULATION OF CELLULAR METABOLISM;REGULATION OF CELLULAR PHYSIOLOGICAL PROCESS;REGULATION OF CELLULAR PROCESS;REGULATION OF METABOLISM;REGULATION OF NUCLEOBASE, NUCLEOSIDE, NUCLEOTIDE AND NUCLEIC ACID METABOLISM;REGULATION OF PHYSIOLOGICAL PROCESS;REGULATION OF TRANSCRIPTION;REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE I PROMOTER;REGULATION OF TRANSCRIPTION, DNA-DEPENDENT;TRANSCRIPTION;TRANSCRIPTION FROM RNA POLYMERASE I PROMOTER;TRANSCRIPTION, DNA-DEPENDENT | AUTOANTIGEN NOR-90;NUCLEOLAR TRANSCRIPTION FACTOR 1;NUCLEOLAR TRANSCRIPTION FACTOR 1 (UPSTREAM BINDING FACTOR 1) (UBF-1) (AUTOANTIGEN NOR-90);RIBOSOMAL RNA UPSTREAM BINDING TRANSCRIPTION FACTOR;RIBOSOMAL RNA UPSTREAM BINDING TRANSCRIPTION FACTOR (FRAGMENT);TRANSCRIPTION FACTOR UBF, NUCLEOLAR;UBF-1;UPSTREAM BINDING TRANSCRIPTION FACTOR, RNA POLYMERASE I;UPSTREAM BINDING TRANSCRIPTION FACTOR, RNA POLYMERASE I (FRAGMENT);UPSTREAM-BINDING FACTOR 1 |
| [Proteome Summary:] Nucleolar transcription factor; implicated in the regulation of rRNA expression |
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Ch25h | 9023 | LIPID METABOLISM;METABOLISM;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM | CHOLESTEROL 25-HYDROXYLASE |
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Top2a | 7153 | AXONOGENESIS;BIOPOLYMER METABOLISM;BRAIN DEVELOPMENT;CELL COMMUNICATION;CELL DEVELOPMENT;CELL DIFFERENTIATION;CELL MIGRATION;CELL MOTILITY;CELL ORGANIZATION AND BIOGENESIS;CELLULAR METABOLISM;CELLULAR MORPHOGENESIS;CELLULAR MORPHOGENESIS DURING DIFFERENTIATION;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;CENTRAL NERVOUS SYSTEM DEVELOPMENT;DEVELOPMENT;DNA METABOLISM;DNA REPAIR;DNA REPLICATION;DNA TOPOLOGICAL CHANGE;DNA UNWINDING DURING REPLICATION;DNA-DEPENDENT DNA REPLICATION;ESTABLISHMENT OF LOCALIZATION;FOREBRAIN DEVELOPMENT;INTRACELLULAR SIGNALING CASCADE;LOCALIZATION;LOCALIZATION OF CELL;LOCOMOTION;MACROMOLECULE METABOLISM;METABOLISM;MORPHOGENESIS;NERVOUS SYSTEM DEVELOPMENT;NEURITE MORPHOGENESIS;NEUROGENESIS;NEURON DEVELOPMENT;NEURON DIFFERENTIATION;NEURON MIGRATION;NEURON MORPHOGENESIS DURING DIFFERENTIATION;NUCLEOBASE, NUCLEOSIDE, NUCLEOTIDE AND NUCLEIC ACID METABOLISM;ORGAN DEVELOPMENT;PHOSPHOINOSITIDE-MEDIATED SIGNALING;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;RESPONSE TO DNA DAMAGE STIMULUS;RESPONSE TO ENDOGENOUS STIMULUS;RESPONSE TO STIMULUS;RESPONSE TO STRESS;SECOND-MESSENGER-MEDIATED SIGNALING;SIGNAL TRANSDUCTION;SYSTEM DEVELOPMENT | 0 DAY NEONATE THYMUS CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:A430094K17 PRODUCT:TOPOISOMERASE (DNA) II BETA, FULL INSERT SEQUENCE.;0 DAY NEONATE THYMUS CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:A430094K17 PRODUCT:TOPOISOMERASE (DNA) II BETA, FULL INSERT SEQUENCE. (FRAGMENT);ADULT MALE AORTA AND VEIN CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:A530071N24 PRODUCT:TOPOISOMERASE (DNA) II BETA, FULL INSERT SEQUENCE.;ADULT MALE AORTA AND VEIN CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:A530071N24 PRODUCT:TOPOISOMERASE (DNA) II BETA, FULL INSERT SEQUENCE. (FRAGMENT);ANTIGEN MLAA-44;DNA TOPOISOMERASE 2-ALPHA;DNA TOPOISOMERASE 2-ALPHA (EC 5.99.1.3) (DNA TOPOISOMERASE II, ALPHA ISOZYME);DNA TOPOISOMERASE 2-BETA;DNA TOPOISOMERASE 2-BETA (EC 5.99.1.3) (DNA TOPOISOMERASE II, BETA ISOZYME);DNA TOPOISOMERASE II BETA;DNA TOPOISOMERASE II BETA (FRAGMENT);DNA TOPOISOMERASE II, ALPHA ISOZYME;DNA TOPOISOMERASE II, BETA ISOZYME;DNA TOPOISOMERASE II, BETA ISOZYME VARIANT;DNA TOPOISOMERASE II, BETA ISOZYME VARIANT (FRAGMENT);HYPOTHETICAL PROTEIN;HYPOTHETICAL PROTEIN (FRAGMENT);II;II ALPHA;II ALPHA-2;II ALPHA-3;II ALPHA-4;II DNA TOPOISOMERASE BETA ISOFORM;IIB;PREDICTED: SIMILAR TO PTEN-LIKE PHOSPHATASE;PROTEIN TYROSINE PHOSPHATASE MITOCHONDRIAL 1, MITOCHONDRIAL PRECURSOR;PROTEIN TYROSINE PHOSPHATASE MITOCHONDRIAL 1, MITOCHONDRIAL PRECURSOR (EC 3.1.3.48) (EC 3.1.3.16);PTEN-LIKE PHOSPHATASE;TOPOISOMERASE (ATP-HYDROLYSING); TOPOISOMERASE II ALPHA;TOPOISOMERASE (ATP-HYDROLYSING); TOPOISOMERASE II BETA;TOPOISOMERASE (DNA) II ALPHA 170KDA;TOPOISOMERASE (DNA) II BETA;TOPOISOMERASE (DNA) II BETA 180KDA;TOPOISOMERASE II;TOPOISOMERASE II (EC 5.99.1.3);TOPOISOMERASE II ALPHA;TOPOISOMERASE II ALPHA (FRAGMENT);TOPOISOMERASE IIB;TOPOISOMERASE IIB (FRAGMENT) |
| [RefSeq Summary:] This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromsome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. ;[RefSeq Summary:] This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, beta, is localized to chromosome 3 and the alpha form is localized to chromosome 17. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. Alternative splicing of this gene results in two transcript variants; however, the second variant has not yet been fully described. |
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Ankrd12 |
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Rrm2 | 6241 | BIOPOLYMER METABOLISM;BIOSYNTHESIS;CELLULAR BIOSYNTHESIS;CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;DEOXYRIBONUCLEOSIDE DIPHOSPHATE METABOLISM;DEOXYRIBONUCLEOTIDE BIOSYNTHESIS;DEOXYRIBONUCLEOTIDE METABOLISM;DNA METABOLISM;DNA REPLICATION;MACROMOLECULE METABOLISM;METABOLISM;NUCLEOBASE, NUCLEOSIDE, NUCLEOTIDE AND NUCLEIC ACID METABOLISM;NUCLEOSIDE DIPHOSPHATE METABOLISM;NUCLEOTIDE BIOSYNTHESIS;NUCLEOTIDE METABOLISM;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM | 12 DAYS EMBRYO EYEBALL CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:D230007O14 PRODUCT:RIBONUCLEOTIDE REDUCTASE M2, FULL INSERT SEQUENCE;13 DAYS EMBRYO LIVER CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I920170D11 PRODUCT:RIBONUCLEOTIDE REDUCTASE M2, FULL INSERT SEQUENCE;13 DAYS EMBRYO LIVER CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I920170D11 PRODUCT:RIBONUCLEOTIDE REDUCTASE M2, FULL INSERT SEQUENCE (8 DAYS EMBRYO WHOLE BODY CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:5730434D10 PRODUCT:RIBONUCLEOTIDE REDUCTASE M2, FULL INSERT SEQUENCE) (BLASTOCYST BLASTOCYST CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I1C0029M05 PRODUCT:RIBONUCLEOTIDE REDUCTASE M2, FULL INSERT SEQUENCE) (BLASTOCYST BLASTOCYST CDNA, RIKEN FULL- LENGTH ENRICHED LIBRARY, CLONE:I1C0038P13 PRODUCT:RIBONUCLEOTIDE REDUCTASE M2, FULL INSERT SEQUENCE) (CRL-1722 L5178Y-R CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I730065L22 PRODUCT:RIBONUCLEOTIDE REDUCTASE M2, FULL INSERT SEQUENCE) (16 DAYS EMBRYO KIDNEY CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I920071O17 PRODUCT:RIBONUCLEOTIDE REDUCTASE M2, FULL INSERT SEQUENCE) (12 DAYS EMBRYO EYEBALL CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:D230007O14 PRODUCT:RIBONUCLEOTIDE REDUCTASE M2, FULL INSERT SEQUENCE);16 DAYS EMBRYO KIDNEY CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I920071O17 PRODUCT:RIBONUCLEOTIDE REDUCTASE M2, FULL INSERT SEQUENCE;8 DAYS EMBRYO WHOLE BODY CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:5730434D10 PRODUCT:RIBONUCLEOTIDE REDUCTASE M2, FULL INSERT SEQUENCE;BLASTOCYST BLASTOCYST CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I1C0029M05 PRODUCT:RIBONUCLEOTIDE REDUCTASE M2, FULL INSERT SEQUENCE;BLASTOCYST BLASTOCYST CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I1C0038P13 PRODUCT:RIBONUCLEOTIDE REDUCTASE M2, FULL INSERT SEQUENCE;CRL-1722 L5178Y-R CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I730058I07 PRODUCT:RIBONUCLEOTIDE REDUCTASE M2, FULL INSERT SEQUENCE;CRL-1722 L5178Y-R CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I730065L22 PRODUCT:RIBONUCLEOTIDE REDUCTASE M2, FULL INSERT SEQUENCE;RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (EC 1.17.4.1) CHAIN M2 ALT_NAMES:RIBONUCLEOTIDE REDUCTASE M2 SUBUNIT;RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (EC 1.17.4.1) SMALL CHAIN ALT_NAMES:RIBONUCLEOTIDE REDUCTASE M2 CHAIN; RIBONUCLEOTIDE REDUCTASE SMALL CHAIN;RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE M2 SUBUNIT;RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE M2 SUBUNIT (EC 1.17.4.1) (RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT) (RIBONUCLEOTIDE REDUCTASE SMALL CHAIN);RIBONUCLEOTIDE REDUCTASE M2;RIBONUCLEOTIDE REDUCTASE M2 POLYPEPTIDE;RIBONUCLEOTIDE REDUCTASE M2 SUBUNIT;RIBONUCLEOTIDE REDUCTASE M2 SUBUNIT (EC 1.17.4.1) (FRAGMENT);RIBONUCLEOTIDE REDUCTASE SMALL CHAIN;RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT;SIMILAR TO RIBONUCLEOTIDE REDUCTASE PROTEIN R2 CLASS I;SIMILAR TO RIBONUCLEOTIDE REDUCTASE PROTEIN R2 CLASS I (FRAGMENT) | HSA00230:PURINE METABOLISM;HSA00240:PYRIMIDINE METABOLISM;MMU00230:PURINE METABOLISM;MMU00240:PYRIMIDINE METABOLISM | [RefSeq Summary:] Ribonucleotide reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. It is composed of 2 non-identical subunits, proteins M1 and M2. Synthesis of M2 is regulated in a cell-cycle dependent fashion. |
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Ccnb2 | 9133 | CELL CYCLE;CELL DIVISION;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;M PHASE;M PHASE OF MITOTIC CELL CYCLE;MITOSIS;MITOTIC CELL CYCLE;PHYSIOLOGICAL PROCESS;REGULATION OF BIOLOGICAL PROCESS;REGULATION OF CELL CYCLE;REGULATION OF CELLULAR PHYSIOLOGICAL PROCESS;REGULATION OF CELLULAR PROCESS;REGULATION OF PHYSIOLOGICAL PROCESS;REGULATION OF PROGRESSION THROUGH CELL CYCLE | CCNB2 PROTEIN;CYCLIN B2;CYCLIN B2 VARIANT;CYCLIN B2 VARIANT (FRAGMENT);G2/MITOTIC-SPECIFIC CYCLIN-B2;HYPOTHETICAL PROTEIN DKFZP434B174.1;MITOTIC SPECIFIC CYCLIN B2 | HSA04110:CELL CYCLE | [RefSeq Summary:] Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control. |
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Racgap1 | 29127 | CELL COMMUNICATION;CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;ELECTRON TRANSPORT;ESTABLISHMENT OF LOCALIZATION;GENERATION OF PRECURSOR METABOLITES AND ENERGY;INTRACELLULAR SIGNALING CASCADE;LOCALIZATION;METABOLISM;PHYSIOLOGICAL PROCESS;SIGNAL TRANSDUCTION;TRANSPORT | CDNA FLJ12664 FIS, CLONE NT2RM4002226, WEAKLY SIMILAR TO GTPASE ACTIVATING PROTEIN ROTUND;GTPASE ACTIVATING PROTEIN;HYPOTHETICAL PROTEIN DKFZP434C011;HYPOTHETICAL PROTEIN DKFZP434C011 (RACGAP1 PROTEIN);HYPOTHETICAL PROTEIN FLJ12664;HYPOTHETICAL PROTEIN FLJ20726;KIAA1478 PROTEIN;KIAA1478 PROTEIN (FRAGMENT);RAC GTPASE ACTIVATING PROTEIN 1;RAC GTPASE ACTIVATING PROTEIN 1 [IMPORTED];RACGAP1 PROTEIN |
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Shcbp1 | 79801 |
| HYPOTHETICAL PROTEIN FLJ22009;HYPOTHETICAL PROTEIN FLJ31369;SHC SH2 DOMAIN-BINDING PROTEIN 1;SHC SH2-DOMAIN BINDING PROTEIN 1;SHCBP1 PROTEIN (FRAGMENT) |
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Eny2 |
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Steap2 | 261729 | CELL ORGANIZATION AND BIOGENESIS;CELLULAR LOCALIZATION;CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;ELECTRON TRANSPORT;ENDOCYTOSIS;ESTABLISHMENT OF CELLULAR LOCALIZATION;ESTABLISHMENT OF LOCALIZATION;GENERATION OF PRECURSOR METABOLITES AND ENERGY;GOLGI TO PLASMA MEMBRANE TRANSPORT;GOLGI VESICLE TRANSPORT;INTRACELLULAR TRANSPORT;LOCALIZATION;METABOLISM;PHYSIOLOGICAL PROCESS;POST-GOLGI VESICLE-MEDIATED TRANSPORT;REGULATED SECRETORY PATHWAY;RESPONSE TO ABIOTIC STIMULUS;RESPONSE TO CHEMICAL STIMULUS;RESPONSE TO ENDOGENOUS STIMULUS;RESPONSE TO HORMONE STIMULUS;RESPONSE TO STIMULUS;SECRETION;SECRETORY PATHWAY;TRANSPORT;VESICLE-MEDIATED TRANSPORT | PROTEIN UPREGULATED IN METASTATIC PROSTATE CANCER;PUMPCN;PUMPCN (PROTEIN UPREGULATED IN METASTATIC PROSTATE CANCER);SIX TRANSMEMBRANE EPITHELIAL ANTIGEN OF THE PROSTATE 2;SIX TRANSMEMBRANE PROSTATE PROTEIN V1;SIX TRANSMEMBRANE PROSTATE PROTEIN V2 |
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Bdkrb2 | 624 | CALCIUM ION HOMEOSTASIS;CATION HOMEOSTASIS;CELL COMMUNICATION;CELL HOMEOSTASIS;CELL ION HOMEOSTASIS;CELL SURFACE RECEPTOR LINKED SIGNAL TRANSDUCTION;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;CIRCULATION;CYTOSOLIC CALCIUM ION HOMEOSTASIS;DEFENSE RESPONSE;DI-, TRI-VALENT INORGANIC CATION HOMEOSTASIS;ELEVATION OF CYTOSOLIC CALCIUM ION CONCENTRATION;ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY;G-PROTEIN COUPLED RECEPTOR PROTEIN SIGNALING PATHWAY;HOMEOSTASIS;IMMUNE RESPONSE;INFLAMMATORY RESPONSE;ION HOMEOSTASIS;METAL ION HOMEOSTASIS;MUSCLE CONTRACTION;NEUROPEPTIDE SIGNALING PATHWAY;NEUROPHYSIOLOGICAL PROCESS;ORGANISMAL PHYSIOLOGICAL PROCESS;PHYSIOLOGICAL PROCESS;RESPONSE TO BIOTIC STIMULUS;RESPONSE TO EXTERNAL STIMULUS;RESPONSE TO OTHER ORGANISM;RESPONSE TO PEST, PATHOGEN OR PARASITE;RESPONSE TO STIMULUS;RESPONSE TO STRESS;RESPONSE TO WOUNDING;SENSORY PERCEPTION;SENSORY PERCEPTION OF PAIN;SIGNAL TRANSDUCTION;SMOOTH MUSCLE CONTRACTION;TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY | B2 BRADYKININ RECEPTOR;B2 BRADYKININ RECEPTOR (BK-2 RECEPTOR) (B2R);B2-BRADYKININ RECEPTOR GENE PROTEIN;B2-BRADYKININ RECEPTOR GENE PROTEIN (FRAGMENT);B2R;BK-2 RECEPTOR;BRADYKININ B2 RECEPTOR;BRADYKININ RECEPTOR;BRADYKININ RECEPTOR B2;BRADYKININ RECEPTOR TYPE B-2;BRADYKININ RECEPTOR, BETA 2;HYPOTHETICAL PROTEIN DKFZP686O088;RECEPTOR | HSA04020:CALCIUM SIGNALING PATHWAY;HSA04080:NEUROACTIVE LIGAND-RECEPTOR INTERACTION;HSA04610:COMPLEMENT AND COAGULATION CASCADES;HSA04810:REGULATION OF ACTIN CYTOSKELETON;MMU04020:CALCIUM SIGNALING PATHWAY;MMU04080:NEUROACTIVE LIGAND-RECEPTOR INTERACTION;MMU04610:COMPLEMENT AND COAGULATION CASCADES;MMU04810:REGULATION OF ACTIN CYTOSKELETON;RNO04020:CALCIUM SIGNALING PATHWAY;RNO04080:NEUROACTIVE LIGAND-RECEPTOR INTERACTION;RNO04610:COMPLEMENT AND COAGULATION CASCADES;RNO04810:REGULATION OF ACTIN CYTOSKELETON | [RefSeq Summary:] This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein. |
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Prc1 | 9055 | CELL CYCLE;CELL DIVISION;CELL ORGANIZATION AND BIOGENESIS;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;CYTOKINESIS;CYTOSKELETON ORGANIZATION AND BIOGENESIS;MICROTUBULE CYTOSKELETON ORGANIZATION AND BIOGENESIS;MICROTUBULE-BASED PROCESS;MITOTIC CELL CYCLE;MITOTIC SPINDLE ELONGATION;MITOTIC SPINDLE ORGANIZATION AND BIOGENESIS;ORGANELLE ORGANIZATION AND BIOGENESIS;PHYSIOLOGICAL PROCESS;SPINDLE ELONGATION;SPINDLE ORGANIZATION AND BIOGENESIS | PRC1 PROTEIN;PROTEIN REGULATING CYTOKINESIS 1;PROTEIN REGULATING CYTOKINESIS 1 (PROTEIN REGULATOR OF CYTOKINESIS 1, ISOFORM 1);PROTEIN REGULATOR OF CYTOKINESIS 1;PROTEIN REGULATOR OF CYTOKINESIS 1 ISOFORM 2;PROTEIN REGULATOR OF CYTOKINESIS 1 ISOFORM 3;PROTEIN REGULATOR OF CYTOKINESIS 1, ISOFORM 1 |
| [RefSeq Summary:] This gene encodes a protein that is involved in cytokinesis. The encoded protein is at high level during S and G2/M and drop dramatically after cell exit mitosis and enter G1. It is located in the nucleus during interphase, and becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. [Proteome Summary:] Protein that associates with the mitotic spindle; required for cytokinesis but not nuclear division |
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Fignl1 | 63979 |
| CDNA FLJ13080 FIS, CLONE NT2RP3002007, WEAKLY SIMILAR TO SAP1 PROTEIN;CDNA FLJ13349 FIS, CLONE OVARC1002138, MODERATELY SIMILAR TO SAP1 PROTEIN;FIDGETIN-LIKE 1;FIDGETIN-LIKE 1 (HYPOTHETICAL PROTEIN FIGNL1);FIGNL1 PROTEIN;HYPOTHETICAL PROTEIN DKFZP434K142;HYPOTHETICAL PROTEIN FIGNL1;HYPOTHETICAL PROTEIN FLJ13080;HYPOTHETICAL PROTEIN FLJ13349 |
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Slco1a5 |
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Luzp5 |
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Retnla |
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Pttg1 | 9232 | BIOPOLYMER METABOLISM;CELL CYCLE;CELL DIVISION;CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;CHROMOSOME SEGREGATION;DNA METABOLISM;DNA REPAIR;DNA REPLICATION AND CHROMOSOME CYCLE;GAMETOGENESIS;M PHASE;M PHASE OF MITOTIC CELL CYCLE;MACROMOLECULE METABOLISM;MALE GAMETE GENERATION;METABOLISM;MITOSIS;MITOTIC CELL CYCLE;NUCLEOBASE, NUCLEOSIDE, NUCLEOTIDE AND NUCLEIC ACID METABOLISM;OBSOLETE BIOLOGICAL PROCESS;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;REPRODUCTION;RESPONSE TO DNA DAMAGE STIMULUS;RESPONSE TO ENDOGENOUS STIMULUS;RESPONSE TO STIMULUS;RESPONSE TO STRESS;SEXUAL REPRODUCTION;SPERMATOGENESIS;TRANSCRIPTION;TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER;TRANSCRIPTION, DNA-DEPENDENT | ESP1-ASSOCIATED PROTEIN;HPTTG;HYPOTHETICAL PROTEIN;HYPOTHETICAL PROTEIN (FRAGMENT);PITUITARY TUMOR TRANSFORMING GENE PROTEIN;PITUITARY TUMOR-TRANSFORMING 1;PITUITARY TUMOR-TRANSFORMING PROTEIN 1;PTTG1 PROTEIN;PTTG1 PROTEIN (PITUITARY TUMOR-TRANSFORMING PROTEIN 1);SECURIN;SECURIN (PITUITARY TUMOR-TRANSFORMING PROTEIN 1) (TUMOR TRANSFORMING PROTEIN 1) (ESP1-ASSOCIATED PROTEIN) (HPTTG);TUMOR TRANSFORMING PROTEIN 1 | HSA04110:CELL CYCLE | [RefSeq Summary:] The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus. |
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C1qa | 712 | ANION TRANSPORT;CELL COMMUNICATION;CELL-CELL SIGNALING;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;COMPLEMENT ACTIVATION;COMPLEMENT ACTIVATION, CLASSICAL PATHWAY;DEFENSE RESPONSE;ESTABLISHMENT OF LOCALIZATION;HUMORAL DEFENSE MECHANISM (SENSU VERTEBRATA);HUMORAL IMMUNE RESPONSE;IMMUNE RESPONSE;INNATE IMMUNE RESPONSE;INORGANIC ANION TRANSPORT;ION TRANSPORT;LOCALIZATION;ORGANISMAL PHYSIOLOGICAL PROCESS;PHOSPHATE TRANSPORT;PHYSIOLOGICAL PROCESS;RESPONSE TO BIOTIC STIMULUS;RESPONSE TO OTHER ORGANISM;RESPONSE TO PEST, PATHOGEN OR PARASITE;RESPONSE TO STIMULUS;RESPONSE TO STRESS;TRANSPORT | ADULT MALE EPIDIDYMIS CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:9230110J15 PRODUCT:COMPLEMENT COMPONENT 1, Q SUBCOMPONENT, ALPHA POLYPEPTIDE, FULL INSERT SEQUENCE;ADULT MALE KIDNEY CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:0610023A02 PRODUCT:COMPLEMENT COMPONENT 1, Q SUBCOMPONENT, ALPHA POLYPEPTIDE, FULL INSERT SEQUENCE;ADULT MALE KIDNEY CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:0610023A02 PRODUCT:COMPLEMENT COMPONENT 1, Q SUBCOMPONENT, ALPHA POLYPEPTIDE, FULL INSERT SEQUENCE (COMPLEMENT COMPONENT 1, Q SUBCOMPONENT, ALPHA POLYPEPTIDE) (OSTEOCLAST-LIKE CELL CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I420009L10 PRODUCT:COMPLEMENT COMPONENT 1, Q SUBCOMPONENT, ALPHA POLYPEPTIDE, FULL INSERT SEQUENCE) (ADULT MALE EPIDIDYMIS CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:9230110J15 PRODUCT:COMPLEMENT COMPONENT 1, Q SUBCOMPONENT, ALPHA POLYPEPTIDE, FULL INSERT SEQUENCE);BONE MARROW MACROPHAGE CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I830015E07 PRODUCT:COMPLEMENT COMPONENT 1, Q SUBCOMPONENT, ALPHA POLYPEPTIDE, FULL INSERT SEQUENCE;COMPLEMENT C1Q A CHAIN PRECURSOR,;COMPLEMENT C1Q SUBCOMPONENT SUBUNIT A PRECURSOR;COMPLEMENT C1Q SUBCOMPONENT, A CHAIN PRECURSOR;COMPLEMENT COMPONENT 1, Q SUBCOMPONENT, A CHAIN;COMPLEMENT COMPONENT 1, Q SUBCOMPONENT, ALPHA POLYPEPTIDE;COMPLEMENT SUBCOMPONENT C1Q CHAIN A PRECURSOR;COMPLEMENT SUBCOMPONENT C1Q CHAIN A PRECURSOR [VALIDATED] ALT_NAMES:COMPLEMENT SUBCOMPONENT C1Q ALPHA CHAIN;COMPONENT 1, Q SUBCOMPONENT, ALPHA POLYPEPTIDE;DC33;OSTEOCLAST-LIKE CELL CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I420009L10 PRODUCT:COMPLEMENT COMPONENT 1, Q SUBCOMPONENT, ALPHA POLYPEPTIDE, FULL INSERT SEQUENCE;OSTEOCLAST-LIKE CELL CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I420016O08 PRODUCT:COMPLEMENT COMPONENT 1, Q SUBCOMPONENT, ALPHA POLYPEPTIDE, FULL INSERT SEQUENCE | HSA04610:COMPLEMENT AND COAGULATION CASCADES;MMU04610:COMPLEMENT AND COAGULATION CASCADES | [RefSeq Summary:] This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the A-chain polypeptide of human complement subcomponent C1q. |
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Kif22 | 3835 | CELL CYCLE;CELL ORGANIZATION AND BIOGENESIS;CELLULAR LOCALIZATION;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;CYTOSKELETON ORGANIZATION AND BIOGENESIS;CYTOSKELETON-DEPENDENT INTRACELLULAR TRANSPORT;ESTABLISHMENT OF CELLULAR LOCALIZATION;ESTABLISHMENT OF LOCALIZATION;INTRACELLULAR TRANSPORT;LOCALIZATION;M PHASE;M PHASE OF MITOTIC CELL CYCLE;MICROTUBULE-BASED MOVEMENT;MICROTUBULE-BASED PROCESS;MITOSIS;MITOTIC CELL CYCLE;ORGANELLE ORGANIZATION AND BIOGENESIS;PHYSIOLOGICAL PROCESS;TRANSPORT | DNA BINDING PROTEIN;KINESIN FAMILY MEMBER 22;KINESIN FAMILY MEMBER 22 VARIANT;KINESIN FAMILY MEMBER 22 VARIANT (FRAGMENT);KINESIN-LIKE DNA-BINDING PROTEIN;KINESIN-LIKE PROTEIN 4;KINESIN-LIKE PROTEIN KIF22;KINESIN-LIKE PROTEIN KIF22 (KINESIN-LIKE DNA-BINDING PROTEIN) (KINESIN-LIKE PROTEIN 4);ORIP BINDING PROTEIN;ORIP BINDING PROTEIN (FRAGMENT);ORIP BINDING PROTEIN LIKE GENE PRODUCT |
| [RefSeq Summary:] The protein encoded by this gene is a member of kinesin-like protein family. This family of proteins are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance. |
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Ttk | 7272 | BIOPOLYMER METABOLISM;BIOPOLYMER MODIFICATION;CELL CYCLE;CELL CYCLE CHECKPOINT;CELL ORGANIZATION AND BIOGENESIS;CELL PROLIFERATION;CELLULAR MACROMOLECULE METABOLISM;CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;CELLULAR PROTEIN METABOLISM;CYTOSKELETON ORGANIZATION AND BIOGENESIS;M PHASE;M PHASE OF MITOTIC CELL CYCLE;MACROMOLECULE METABOLISM;METABOLISM;MICROTUBULE CYTOSKELETON ORGANIZATION AND BIOGENESIS;MICROTUBULE-BASED PROCESS;MITOSIS;MITOTIC CELL CYCLE;MITOTIC CHECKPOINT;MITOTIC SPINDLE CHECKPOINT;MITOTIC SPINDLE ORGANIZATION AND BIOGENESIS;ORGANELLE ORGANIZATION AND BIOGENESIS;PHOSPHATE METABOLISM;PHOSPHORUS METABOLISM;PHOSPHORYLATION;PHYSIOLOGICAL PROCESS;POSITIVE REGULATION OF BIOLOGICAL PROCESS;POSITIVE REGULATION OF CELL PROLIFERATION;POSITIVE REGULATION OF CELLULAR PHYSIOLOGICAL PROCESS;POSITIVE REGULATION OF CELLULAR PROCESS;POSITIVE REGULATION OF PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;PROTEIN AMINO ACID PHOSPHORYLATION;PROTEIN METABOLISM;PROTEIN MODIFICATION;REGULATION OF BIOLOGICAL PROCESS;REGULATION OF CELL CYCLE;REGULATION OF CELL PROLIFERATION;REGULATION OF CELLULAR PHYSIOLOGICAL PROCESS;REGULATION OF CELLULAR PROCESS;REGULATION OF MITOSIS;REGULATION OF PHYSIOLOGICAL PROCESS;REGULATION OF PROGRESSION THROUGH CELL CYCLE;SPINDLE CHECKPOINT;SPINDLE ORGANIZATION AND BIOGENESIS | DUAL SPECIFICITY PROTEIN KINASE TTK;DUAL SPECIFICITY PROTEIN KINASE TTK (EC 2.7.1.-) (PHOSPHOTYROSINE PICKED THREONINE-PROTEIN KINASE) (PYT);PHOSPHOTYROSINE PICKED THREONINE KINASE;PHOSPHOTYROSINE PICKED THREONINE KINASE (PYT) (FRAGMENT);PHOSPHOTYROSINE PICKED THREONINE-PROTEIN KINASE;PROTEIN KINASE TTK (EC 2.7.1.-) ALT_NAMES:PHOSPHOTYROSINE PICKED THREONINE KINASE (PYT);PYT;TTK PROTEIN KINASE;TTK PROTEIN KINASE (FRAGMENT) | HSA00562:INOSITOL PHOSPHATE METABOLISM;HSA00632:BENZOATE DEGRADATION VIA COA LIGATION;HSA00760:NICOTINATE AND NICOTINAMIDE METABOLISM;HSA04070:PHOSPHATIDYLINOSITOL SIGNALING SYSTEM |
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Ctsk | 1513 | CELLULAR MACROMOLECULE METABOLISM;CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;CELLULAR PROTEIN METABOLISM;MACROMOLECULE METABOLISM;METABOLISM;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;PROTEIN METABOLISM;PROTEOLYSIS | CATHEPSIN K;CATHEPSIN K (EC 3.4.22.-) PRECURSOR ALT_NAMES:CATHEPSIN O2;CATHEPSIN K (PYCNODYSOSTOSIS);CATHEPSIN K PRECURSOR;CATHEPSIN K PRECURSOR (EC 3.4.22.38) (CATHEPSIN O) (CATHEPSIN X) (CATHEPSIN O2);CATHEPSIN O;CATHEPSIN O2;CATHEPSIN X;CTSK PROTEIN;CTSK PROTEIN (CATHEPSIN K) (PYCNODYSOSTOSIS);CTSK PROTEIN (FRAGMENT);PYCNODYSOSTOSIS;X |
| [RefSeq Summary:] The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. |
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Prc1 | 9055 | CELL CYCLE;CELL DIVISION;CELL ORGANIZATION AND BIOGENESIS;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;CYTOKINESIS;CYTOSKELETON ORGANIZATION AND BIOGENESIS;MICROTUBULE CYTOSKELETON ORGANIZATION AND BIOGENESIS;MICROTUBULE-BASED PROCESS;MITOTIC CELL CYCLE;MITOTIC SPINDLE ELONGATION;MITOTIC SPINDLE ORGANIZATION AND BIOGENESIS;ORGANELLE ORGANIZATION AND BIOGENESIS;PHYSIOLOGICAL PROCESS;SPINDLE ELONGATION;SPINDLE ORGANIZATION AND BIOGENESIS | PRC1 PROTEIN;PROTEIN REGULATING CYTOKINESIS 1;PROTEIN REGULATING CYTOKINESIS 1 (PROTEIN REGULATOR OF CYTOKINESIS 1, ISOFORM 1);PROTEIN REGULATOR OF CYTOKINESIS 1;PROTEIN REGULATOR OF CYTOKINESIS 1 ISOFORM 2;PROTEIN REGULATOR OF CYTOKINESIS 1 ISOFORM 3;PROTEIN REGULATOR OF CYTOKINESIS 1, ISOFORM 1 |
| [RefSeq Summary:] This gene encodes a protein that is involved in cytokinesis. The encoded protein is at high level during S and G2/M and drop dramatically after cell exit mitosis and enter G1. It is located in the nucleus during interphase, and becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. [Proteome Summary:] Protein that associates with the mitotic spindle; required for cytokinesis but not nuclear division |
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C2 | 717 | CELLULAR MACROMOLECULE METABOLISM;CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;CELLULAR PROTEIN METABOLISM;COMPLEMENT ACTIVATION;COMPLEMENT ACTIVATION, CLASSICAL PATHWAY;DEFENSE RESPONSE;HUMORAL DEFENSE MECHANISM (SENSU VERTEBRATA);HUMORAL IMMUNE RESPONSE;IMMUNE RESPONSE;INNATE IMMUNE RESPONSE;MACROMOLECULE METABOLISM;METABOLISM;ORGANISMAL PHYSIOLOGICAL PROCESS;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;PROTEIN METABOLISM;PROTEOLYSIS;RESPONSE TO BIOTIC STIMULUS;RESPONSE TO OTHER ORGANISM;RESPONSE TO PEST, PATHOGEN OR PARASITE;RESPONSE TO STIMULUS;RESPONSE TO STRESS | 17 DAYS PREGNANT ADULT FEMALE AMNION CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I920060I06 PRODUCT:COMPLEMENT COMPONENT 2 (WITHIN H-2S), FULL INSERT SEQUENCE;C2;C2 (COMPLEMENT COMPONENT 2) (WITHIN H-2S) (17 DAYS PREGNANT ADULT FEMALE AMNION CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I920060I06 PRODUCT:COMPLEMENT COMPONENT 2 (WITHIN H-2S), FULL INSERT SEQUENCE);C2 PROTEIN;C2 PROTEIN (COMPLEMENT COMPONENT 2);C2 PROTEIN (FRAGMENT);C3/C5 CONVERTASE;CLASSICAL-COMPLEMENT-PATHWAY C3/C5 CONVERTASE (EC 3.4.21.43) C2 COMPONENT PRECURSOR ALT_NAMES:C3 CONVERTASE; C5 CONVERTASE; COMPLEMENT C2;COMPLEMENT C2;COMPLEMENT C2 (FRAGMENT);COMPLEMENT C2 PRECURSOR;COMPLEMENT C2 PRECURSOR (EC 3.4.21.43) (C3/C5 CONVERTASE) [CONTAINS: COMPLEMENT C2B FRAGMENT; COMPLEMENT C2A FRAGMENT];COMPLEMENT C2 PRECURSOR [VALIDATED];COMPLEMENT C2 PRECURSOR [VALIDATED] CONTAINS:CLASSICAL-COMPLEMENT-PATHWAY C3/C5 CONVERTASE (EC 3.4.21.43) C2A SUBUNIT; CLASSICAL-COMPLEMENT-PATHWAY C3/C5 CONVERTASE (EC 3.4.21.43) C2B SUBUNIT;COMPLEMENT COMPONENT 2;COMPLEMENT COMPONENT 2 (FRAGMENT);COMPLEMENT COMPONENT 2 (OTTHUMP00000062690);COMPLEMENT COMPONENT 2 (WITHIN H-2S);COMPLEMENT COMPONENT 2 VARIANT;COMPLEMENT COMPONENT 2 VARIANT (FRAGMENT);COMPLEMENT COMPONENT C2;COMPLEMENT COMPONENT C2 (FRAGMENT);COMPLEMENT FACTOR C2;COMPLEMENT FACTOR C2 (FRAGMENT);COMPLEMENT PROTEIN;COMPLEMENT PROTEIN (FRAGMENT);COMPONENT C2;HYPOTHETICAL PROTEIN DKFZP779M0311;HYPOTHETICAL PROTEIN DKFZP779M0311 (FRAGMENT);MHC CLASS III H2-C2 COMPLEMENT COMPONENT MRNA (H-2-D), PARTIAL CDS.;MHC CLASS III H2-C2 COMPLEMENT COMPONENT MRNA (H-2-D), PARTIAL CDS. (FRAGMENT);OTTHUMP00000062690;WITHIN H-2S | HSA04610:COMPLEMENT AND COAGULATION CASCADES;MMU04610:COMPLEMENT AND COAGULATION CASCADES;RNO04610:COMPLEMENT AND COAGULATION CASCADES | [RefSeq Summary:] Component C2 is part of the classical pathway of complement system. Activated C1 cleaves C2 into C2a and C2b. C2a leads to activation of C3. Deficiency of C2 has been reported to associated with certain autoimmune diseases. |
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C1r | 715 | ACUTE-PHASE RESPONSE;CELLULAR MACROMOLECULE METABOLISM;CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;CELLULAR PROTEIN METABOLISM;COMPLEMENT ACTIVATION;COMPLEMENT ACTIVATION, CLASSICAL PATHWAY;DEFENSE RESPONSE;HUMORAL DEFENSE MECHANISM (SENSU VERTEBRATA);HUMORAL IMMUNE RESPONSE;IMMUNE RESPONSE;INNATE IMMUNE RESPONSE;MACROMOLECULE METABOLISM;METABOLISM;ORGANISMAL PHYSIOLOGICAL PROCESS;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;PROTEIN METABOLISM;PROTEOLYSIS;RESPONSE TO BIOTIC STIMULUS;RESPONSE TO OTHER ORGANISM;RESPONSE TO PEST, PATHOGEN OR PARASITE;RESPONSE TO STIMULUS;RESPONSE TO STRESS | 0 DAY NEONATE THYMUS CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:A430084L11 PRODUCT:COMPLEMENT COMPONENT 1, R SUBCOMPONENT, FULL INSERT SEQUENCE;ADULT MALE TESTIS CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:4930520I22 PRODUCT:COMPLEMENT COMPONENT 1, R SUBCOMPONENT, FULL INSERT SEQUENCE.;ADULT MALE TESTIS CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:4930520I22 PRODUCT:COMPLEMENT COMPONENT 1, R SUBCOMPONENT, FULL INSERT SEQUENCE. (FRAGMENT);COMPLEMENT C1R SUBCOMPONENT PRECURSOR;COMPLEMENT C1R SUBCOMPONENT PRECURSOR (EC 3.4.21.41) (COMPLEMENT COMPONENT 1, R SUBCOMPONENT) [CONTAINS: COMPLEMENT C1R SUBCOMPONENT HEAVY CHAIN; COMPLEMENT C1R SUBCOMPONENT LIGHT CHAIN];COMPLEMENT C1R-A SUBCOMPONENT PRECURSOR;COMPLEMENT C1R-A SUBCOMPONENT PRECURSOR (EC 3.4.21.41) (COMPLEMENT COMPONENT 1, R-A SUBCOMPONENT) [CONTAINS: COMPLEMENT C1R-A SUBCOMPONENT HEAVY CHAIN; COMPLEMENT C1R-A SUBCOMPONENT LIGHT CHAIN];COMPLEMENT C1R-B SUBCOMPONENT PRECURSOR;COMPLEMENT C1R-B SUBCOMPONENT PRECURSOR (EC 3.4.21.41) (COMPLEMENT COMPONENT 1, R-B SUBCOMPONENT) [CONTAINS: COMPLEMENT C1R-B SUBCOMPONENT HEAVY CHAIN; COMPLEMENT C1R-B SUBCOMPONENT LIGHT CHAIN];COMPLEMENT COMPONENT 1, R SUBCOMPONENT;COMPLEMENT COMPONENT 1, R SUBCOMPONENT VARIANT;COMPLEMENT COMPONENT 1, R SUBCOMPONENT VARIANT (FRAGMENT);COMPLEMENT COMPONENT 1, R SUBCOMPONENT, B;COMPLEMENT COMPONENT 1, R-A SUBCOMPONENT;COMPLEMENT COMPONENT 1, R-B SUBCOMPONENT;COMPLEMENT COMPONENT C1RB;COMPLEMENT COMPONENT C1RB (FRAGMENT);COMPLEMENT SUBCOMPONENT C1R (EC 3.4.21.41) PRECURSOR [VALIDATED];HYPOTHETICAL PROTEIN DKFZP686O02154;PROTEASE | HSA04610:COMPLEMENT AND COAGULATION CASCADES;MMU04610:COMPLEMENT AND COAGULATION CASCADES |
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Tpx2 |
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Msln | 10232 | CELL ADHESION;CELLULAR PROCESS | CAK1 ANTIGEN;MEGAKARYOCYTE POTENTIATING FACTOR;MEGAKARYOCYTE POTENTIATING FACTOR (FRAGMENT);MEGAKARYOCYTE POTENTIATING FACTOR,;MESOTHELIN;MESOTHELIN PRECURSOR;MESOTHELIN PRECURSOR (CAK1 ANTIGEN);MESOTHELIN, ISOFORM 1 PREPROPROTEIN;MESOTHELIN/MEGAKARYOCYTE POTENTIATING FACTOR;MESOTHELIN/MEGAKARYOCYTE POTENTIATING FACTOR (FRAGMENT);OTTHUMP00000045636;PRE-PRO-MEGAKARYCYTE POTENTIATING FACTOR;PRE-PRO-MEGAKARYOCYTE POTENTIATING FACTOR PRECURSOR |
| [RefSeq Summary:] An antibody that reacts with ovarian cancers and mesotheliomas was used to isolate a cell surface antigen named mesothelin. Although the function of mesothelin is unknown, it may play a role in cellular adhesion and is present on mesothelium, mesotheliomas, and ovarian cancers. Three transcript variants have been described for this gene and their protein products were initially named megakaryocyte potentiating factor (MPF), mesothelin, and the soluble member(s) of the mesothelin/MPF family. The protein isoform named MPF is a cytokine with megakaryocyte potentiating activity. The soluble member encoded by the third splice variant is detected in ovarian carcinoma; the full length sequence of the third variant has not been described. |
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Akr1b8 |
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Cdca8 | 55143 | CELL DIVISION;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;PHYSIOLOGICAL PROCESS | CDCA8 PROTEIN;CELL DIVISION CYCLE ASSOCIATED 8;CELL DIVISION CYCLE ASSOCIATED 8 VARIANT;CELL DIVISION CYCLE ASSOCIATED 8 VARIANT (FRAGMENT);HYPOTHETICAL PROTEIN FLJ10468;HYPOTHETICAL PROTEIN FLJ10468 (HYPOTHETICAL PROTEIN FLJ12042) (HYPOTHETICAL PROTEIN FLJ12544) (CDCA8 PROTEIN) (CELL DIVISION CYCLE ASSOCIATED 8) (PLURIPOTENT EMBRYONIC STEM CELL-RELATED PROTEIN 3);HYPOTHETICAL PROTEIN FLJ12042;HYPOTHETICAL PROTEIN FLJ12544;PLURIPOTENT EMBRYONIC STEM CELL-RELATED PROTEIN 3 |
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Elp4 | 26610 |
| DJ68P15A.1;DJ68P15A.1 (NOVEL PROTEIN) (FRAGMENT);ELONGATION PROTEIN 4 HOMOLOG;ELONGATION PROTEIN 4 HOMOLOG (S. CEREVISIAE);HYPOTHETICAL PROTEIN DKFZP564P2272;HYPOTHETICAL PROTEIN FLJ20498;HYPOTHETICAL PROTEIN FLJ20498 (HYPOTHETICAL PROTEIN DKFZP564P2272);LIKELY ORTHOLOG OF MOUSE ELONGATION PROTEIN 4 HOMOLOG (S. CEREVISIAE);NOVEL PROTEIN;PAXNEB PROTEIN;PAXNEB PROTEIN (FRAGMENT) |
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C2 | 717 | CELLULAR MACROMOLECULE METABOLISM;CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;CELLULAR PROTEIN METABOLISM;COMPLEMENT ACTIVATION;COMPLEMENT ACTIVATION, CLASSICAL PATHWAY;DEFENSE RESPONSE;HUMORAL DEFENSE MECHANISM (SENSU VERTEBRATA);HUMORAL IMMUNE RESPONSE;IMMUNE RESPONSE;INNATE IMMUNE RESPONSE;MACROMOLECULE METABOLISM;METABOLISM;ORGANISMAL PHYSIOLOGICAL PROCESS;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;PROTEIN METABOLISM;PROTEOLYSIS;RESPONSE TO BIOTIC STIMULUS;RESPONSE TO OTHER ORGANISM;RESPONSE TO PEST, PATHOGEN OR PARASITE;RESPONSE TO STIMULUS;RESPONSE TO STRESS | 17 DAYS PREGNANT ADULT FEMALE AMNION CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I920060I06 PRODUCT:COMPLEMENT COMPONENT 2 (WITHIN H-2S), FULL INSERT SEQUENCE;C2;C2 (COMPLEMENT COMPONENT 2) (WITHIN H-2S) (17 DAYS PREGNANT ADULT FEMALE AMNION CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I920060I06 PRODUCT:COMPLEMENT COMPONENT 2 (WITHIN H-2S), FULL INSERT SEQUENCE);C2 PROTEIN;C2 PROTEIN (COMPLEMENT COMPONENT 2);C2 PROTEIN (FRAGMENT);C3/C5 CONVERTASE;CLASSICAL-COMPLEMENT-PATHWAY C3/C5 CONVERTASE (EC 3.4.21.43) C2 COMPONENT PRECURSOR ALT_NAMES:C3 CONVERTASE; C5 CONVERTASE; COMPLEMENT C2;COMPLEMENT C2;COMPLEMENT C2 (FRAGMENT);COMPLEMENT C2 PRECURSOR;COMPLEMENT C2 PRECURSOR (EC 3.4.21.43) (C3/C5 CONVERTASE) [CONTAINS: COMPLEMENT C2B FRAGMENT; COMPLEMENT C2A FRAGMENT];COMPLEMENT C2 PRECURSOR [VALIDATED];COMPLEMENT C2 PRECURSOR [VALIDATED] CONTAINS:CLASSICAL-COMPLEMENT-PATHWAY C3/C5 CONVERTASE (EC 3.4.21.43) C2A SUBUNIT; CLASSICAL-COMPLEMENT-PATHWAY C3/C5 CONVERTASE (EC 3.4.21.43) C2B SUBUNIT;COMPLEMENT COMPONENT 2;COMPLEMENT COMPONENT 2 (FRAGMENT);COMPLEMENT COMPONENT 2 (OTTHUMP00000062690);COMPLEMENT COMPONENT 2 (WITHIN H-2S);COMPLEMENT COMPONENT 2 VARIANT;COMPLEMENT COMPONENT 2 VARIANT (FRAGMENT);COMPLEMENT COMPONENT C2;COMPLEMENT COMPONENT C2 (FRAGMENT);COMPLEMENT FACTOR C2;COMPLEMENT FACTOR C2 (FRAGMENT);COMPLEMENT PROTEIN;COMPLEMENT PROTEIN (FRAGMENT);COMPONENT C2;HYPOTHETICAL PROTEIN DKFZP779M0311;HYPOTHETICAL PROTEIN DKFZP779M0311 (FRAGMENT);MHC CLASS III H2-C2 COMPLEMENT COMPONENT MRNA (H-2-D), PARTIAL CDS.;MHC CLASS III H2-C2 COMPLEMENT COMPONENT MRNA (H-2-D), PARTIAL CDS. (FRAGMENT);OTTHUMP00000062690;WITHIN H-2S | HSA04610:COMPLEMENT AND COAGULATION CASCADES;MMU04610:COMPLEMENT AND COAGULATION CASCADES;RNO04610:COMPLEMENT AND COAGULATION CASCADES | [RefSeq Summary:] Component C2 is part of the classical pathway of complement system. Activated C1 cleaves C2 into C2a and C2b. C2a leads to activation of C3. Deficiency of C2 has been reported to associated with certain autoimmune diseases. |
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Palmd | 54873 | CELL ORGANIZATION AND BIOGENESIS;CELLULAR MORPHOGENESIS;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;DEVELOPMENT;MORPHOGENESIS;PHYSIOLOGICAL PROCESS;REGULATION OF CELL SHAPE | C1ORF11;C1ORF11 (FRAGMENT);C1ORF11; ALTERNATIVE SPLICING FORM 1;C1ORF11; ALTERNATIVE SPLICING FORM 1 (FRAGMENT);C1ORF11; ALTERNATIVE SPLICING FORM 1 (PARALEMNIN-LIKE PROTEIN) (PALMDELPHIN) (HYPOTHETICAL PROTEIN FLJ20271);C1ORF11; ALTERNATIVE SPLICING FORM 2;HYPOTHETICAL PROTEIN FLJ20271;HYPOTHETICAL PROTEIN FLJ21001;PALMDELPHIN;PARALEMNIN-LIKE PROTEIN |
| [Proteome Summary:] Protein with low similarity to PALM (paralemmin) |
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Pdgfd |
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Samd14 |
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Mageh1 | 28986 | APOPTOSIS;CELL DEATH;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;DEATH;PHYSIOLOGICAL PROCESS;PROGRAMMED CELL DEATH | APOPTOSIS-RELATED PROTEIN 1;APR-1;MAGE-H1 ANTIGEN;MELANOMA ANTIGEN FAMILY H, 1;MELANOMA-ASSOCIATED ANTIGEN H1;MELANOMA-ASSOCIATED ANTIGEN H1 (MAGE-H1 ANTIGEN) (RESTIN) (APOPTOSIS- RELATED PROTEIN 1) (APR-1);RESTIN |
| [RefSeq Summary:] This gene is thought to be involved in apoptosis. Multiple polyadenylation sites have been found for this gene. |
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Zadh1 | 145482 |
| ZINC BINDING ALCOHOL DEHYDROGENASE;ZINC BINDING ALCOHOL DEHYDROGENASE, DOMAIN CONTAINING 1;ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN CONTAINING PROTEIN 1 (EC 1.-.-.-);ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 1 |
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Depdc1a |
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Anln | 54443 | CELL CYCLE;CELL DIVISION;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;CYTOKINESIS;M PHASE;M PHASE OF MITOTIC CELL CYCLE;MITOSIS;MITOTIC CELL CYCLE;PHYSIOLOGICAL PROCESS;REGULATION OF BIOLOGICAL PROCESS;REGULATION OF CELL CYCLE;REGULATION OF CELLULAR PHYSIOLOGICAL PROCESS;REGULATION OF CELLULAR PROCESS;REGULATION OF EXIT FROM MITOSIS;REGULATION OF MITOSIS;REGULATION OF PHYSIOLOGICAL PROCESS;REGULATION OF PROGRESSION THROUGH CELL CYCLE;SEPTIN RING ASSEMBLY;SEPTIN RING ORGANIZATION | ACTIN BINDING PROTEIN ANILLIN;ANILLIN, ACTIN BINDING PROTEIN (SCRAPS HOMOLOG, DROSOPHILA);ANLN PROTEIN;CDNA FLJ10610 FIS, CLONE NT2RP2005293;CDNA FLJ13146 FIS, CLONE NT2RP3003311;HYPOTHETICAL PROTEIN DKFZP779A055;HYPOTHETICAL PROTEIN DKFZP779A055 (FRAGMENT);HYPOTHETICAL PROTEIN FLJ10606;HYPOTHETICAL PROTEIN FLJ10606 (ANLN PROTEIN);HYPOTHETICAL PROTEIN FLJ10610;HYPOTHETICAL PROTEIN FLJ13146 |
| [Proteome Summary:] Actin binding protein that interacts with cleavage furrow proteins such as septins and may play a role in cytokinesis |
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Prim2 |
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Lig1 | 3978 | BIOPOLYMER METABOLISM;CELL CYCLE;CELL DIVISION;CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;DEVELOPMENT;DNA METABOLISM;DNA RECOMBINATION;DNA REPAIR;DNA REPLICATION;MACROMOLECULE METABOLISM;METABOLISM;MORPHOGENESIS;NUCLEOBASE, NUCLEOSIDE, NUCLEOTIDE AND NUCLEIC ACID METABOLISM;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;RESPONSE TO DNA DAMAGE STIMULUS;RESPONSE TO ENDOGENOUS STIMULUS;RESPONSE TO STIMULUS;RESPONSE TO STRESS | (PROTEIN FOR MGC:130025);DNA LIGASE (ATP) (EC 6.5.1.1) I ALT_NAMES:DNA JOINASE; DNA REPAIR ENZYME; POLYDEOXYRIBONUCLEOTIDE SYNTHASE (ATP); POLYNUCLEOTIDE LIGASE; SEALASE;DNA LIGASE 1;DNA LIGASE I;DNA LIGASE I (EC 6.5.1.1) (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [ATP]);DNA LIGASE I VARIANT;DNA LIGASE I VARIANT (FRAGMENT);LIGASE I, DNA, ATP-DEPENDENT;LIGASE I, DNA, ATP-DEPENDENT (FRAGMENT);POLYDEOXYRIBONUCLEOTIDE SYNTHASE [ATP] 1 |
| [RefSeq Summary:] LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. |
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Ubxd2 | 23190 | CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;METABOLISM;NUCLEOBASE, NUCLEOSIDE, NUCLEOTIDE AND NUCLEIC ACID METABOLISM;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;REGULATION OF BIOLOGICAL PROCESS;REGULATION OF CELLULAR METABOLISM;REGULATION OF CELLULAR PHYSIOLOGICAL PROCESS;REGULATION OF CELLULAR PROCESS;REGULATION OF METABOLISM;REGULATION OF NUCLEOBASE, NUCLEOSIDE, NUCLEOTIDE AND NUCLEIC ACID METABOLISM;REGULATION OF PHYSIOLOGICAL PROCESS;REGULATION OF TRANSCRIPTION;REGULATION OF TRANSCRIPTION, DNA-DEPENDENT;TRANSCRIPTION;TRANSCRIPTION, DNA-DEPENDENT | HYPOTHETICAL PROTEIN UBXD2;UBX DOMAIN CONTAINING 2;UBX DOMAIN-CONTAINING PROTEIN 2;UBXD2 PROTEIN |
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Pcdh7 | 5099 | CELL ADHESION;CELL-CELL ADHESION;CELLULAR PROCESS;HOMOPHILIC CELL ADHESION | BH-PCDH;BH-PROTOCADHERIN (BRAIN-HEART);BH-PROTOCADHERIN PCDH7 (CLONE BH-PCDH-B);BH-PROTOCADHERIN PCDH7 (CLONE BH-PCDH-C);BRAIN-HEART PROTOCADHERIN;HYPOTHETICAL PROTEIN PCDH7;HYPOTHETICAL PROTEIN PCDH7 (FRAGMENT);PROTOCADHERIN 7 ISOFORM A PRECURSOR;PROTOCADHERIN 7 ISOFORM B PRECURSOR;PROTOCADHERIN 7 ISOFORM C PRECURSOR;PROTOCADHERIN 7 PRECURSOR;PROTOCADHERIN 7 PRECURSOR (BRAIN-HEART PROTOCADHERIN) (BH-PCDH) |
| [RefSeq Summary:] This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes a protein with an extracellular domain containing 7 cadherin repeats. The gene product is an integral membrane protein that is thought to function in cell-cell recognition and adhesion. Alternative splicing yields isoforms with unique cytoplasmic tails. |
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Incenp | 3619 | CELL CYCLE;CELL DIVISION;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;M PHASE;M PHASE OF MITOTIC CELL CYCLE;MITOSIS;MITOTIC CELL CYCLE;PHYSIOLOGICAL PROCESS | INCENP PROTEIN;INNER CENTROMERE PROTEIN;INNER CENTROMERE PROTEIN (INCENP PROTEIN);INNER CENTROMERE PROTEIN ANTIGENS 135/155KDA |
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Nup54 | 53371 | CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;ESTABLISHMENT OF LOCALIZATION;LOCALIZATION;PHYSIOLOGICAL PROCESS;TRANSPORT | 54 KDA NUCLEOPORIN;HYPOTHETICAL PROTEIN DKFZP434L1613;HYPOTHETICAL PROTEIN DKFZP434L1613.1;NUCLEOPORIN 54KDA;NUCLEOPORIN 54KDA VARIANT;NUCLEOPORIN 54KDA VARIANT (FRAGMENT);NUCLEOPORIN P54;NUCLEOPORIN P54 (54 KDA NUCLEOPORIN);P54 PROTEIN |
| [RefSeq Summary:] The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the phe-gly (FG) repeat-containing nucleoporin subset. |
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Fxr1h |
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Slc38a2 | 54407 | AMINE TRANSPORT;AMINO ACID TRANSPORT;CARBOXYLIC ACID TRANSPORT;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;ESTABLISHMENT OF LOCALIZATION;GAS TRANSPORT;LOCALIZATION;ORGANIC ACID TRANSPORT;OXYGEN TRANSPORT;PHYSIOLOGICAL PROCESS;TRANSPORT | AMINO ACID TRANSPORTER SYSTEM A;AMINO ACID TRANSPORTER SYSTEM A (HYPOTHETICAL PROTEIN KIAA1382) (AMINO ACID TRANSPORTER SYSTEM A2) (SOLUTE CARRIER FAMILY 38, MEMBER 2);AMINO ACID TRANSPORTER SYSTEM A2;CDNA FLJ10838 FIS, CLONE NT2RP4001274, WEAKLY SIMILAR TO HUMAN TRANSPORTER PROTEIN (G17) MRNA;HYPOTHETICAL PROTEIN FLJ10838;HYPOTHETICAL PROTEIN FLJ23945;HYPOTHETICAL PROTEIN KIAA1382;PRO1068;PUTATIVE 40-9-1 PROTEIN;SLC38A2 PROTEIN;SOLUTE CARRIER FAMILY 38, MEMBER 2 |
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Tmem144 |
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Sap30bp |
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Sparcl1 | 8404 |
| HEVIN;HEVIN PRECURSOR;HIGH ENDOTHELIAL VENULE PROTEIN;MAST 9;PROLIFERATION-INDUCING PROTEIN 33;SPARC-LIKE 1;SPARC-LIKE 1 (MAST9, HEVIN);SPARC-LIKE PROTEIN 1 PRECURSOR;SPARC-LIKE PROTEIN 1 PRECURSOR (HIGH ENDOTHELIAL VENULE PROTEIN) (HEVIN) (MAST 9) |
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Atp6v1g1 | 9550 | ATP BIOSYNTHESIS;ATP METABOLISM;BIOSYNTHESIS;CATION TRANSPORT;CELLULAR BIOSYNTHESIS;CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;COENZYME BIOSYNTHESIS;COENZYME METABOLISM;COFACTOR BIOSYNTHESIS;COFACTOR METABOLISM;ESTABLISHMENT OF LOCALIZATION;HYDROGEN TRANSPORT;ION TRANSPORT;LOCALIZATION;METABOLISM;MONOVALENT INORGANIC CATION TRANSPORT;NUCLEOBASE, NUCLEOSIDE, NUCLEOTIDE AND NUCLEIC ACID METABOLISM;NUCLEOSIDE TRIPHOSPHATE BIOSYNTHESIS;NUCLEOSIDE TRIPHOSPHATE METABOLISM;NUCLEOTIDE BIOSYNTHESIS;NUCLEOTIDE METABOLISM;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;PROTON TRANSPORT;PURINE NUCLEOSIDE TRIPHOSPHATE BIOSYNTHESIS;PURINE NUCLEOSIDE TRIPHOSPHATE METABOLISM;PURINE NUCLEOTIDE BIOSYNTHESIS;PURINE NUCLEOTIDE METABOLISM;PURINE RIBONUCLEOSIDE TRIPHOSPHATE BIOSYNTHESIS;PURINE RIBONUCLEOSIDE TRIPHOSPHATE METABOLISM;PURINE RIBONUCLEOTIDE BIOSYNTHESIS;PURINE RIBONUCLEOTIDE METABOLISM;RIBONUCLEOSIDE TRIPHOSPHATE BIOSYNTHESIS;RIBONUCLEOSIDE TRIPHOSPHATE METABOLISM;RIBONUCLEOTIDE BIOSYNTHESIS;RIBONUCLEOTIDE METABOLISM;TRANSPORT | 12 DAYS EMBRYO MALE WOLFFIAN DUCT INCLUDES SURROUNDING REGION CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:6720467K22 PRODUCT:SIMILAR TO VACUOLAR ATP SYNTHASE SUBUNIT G 3;12 DAYS EMBRYO MALE WOLFFIAN DUCT INCLUDES SURROUNDING REGION CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:6720467K22 PRODUCT:SIMILAR TO VACUOLAR ATP SYNTHASE SUBUNIT G 3 (EC 3.6.3.14) (V-ATPASE G SUBUNIT 3) (VACUOLAR PROTON PUMP G SUBUNIT 3) (V-ATPASE 13 KDA SUBUNIT 3) (ATPASE, H+ TRANSPORTING, V1 SUBUNIT G, ISOFORM 3) (PROTON- TRANSLOCATING ATPASE G SUBUNIT ISOFORM G3);16 DAYS EMBRYO HEAD CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:C130051G04 PRODUCT:ATPASE, H+ TRANSPORTING, LYSOSOMAL (VACUOLAR PROTON PUMP), FULL INSERT SEQUENCE;17 DAYS PREGNANT ADULT FEMALE AMNION CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I920069C17 PRODUCT:ATPASE, H+ TRANSPORTING, V1 SUBUNIT G ISOFORM 1, FULL INSERT SEQUENCE;2 DAYS NEONATE THYMUS THYMIC CELLS CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:E430024D16 PRODUCT:ATPASE, H+ TRANSPORTING, LYSOSOMAL (VACUOLAR PROTON PUMP), FULL INSERT SEQUENCE;ATP6V1G1 PROTEIN;ATP6V1G1 PROTEIN (ATPASE, H+ TRANSPORTING, LYSOSOMAL 13KDA, V1 SUBUNIT G ISOFORM 1);ATP6V1G2 PROTEIN;ATP6V1G2 PROTEIN (FRAGMENT);ATP6V1G3 PROTEIN;ATPASE, H+ TRANSPORTING, LYSOSOMAL 13KDA, V1 SUBUNIT G ISOFORM 1;ATPASE, H+ TRANSPORTING, LYSOSOMAL 13KDA, V1 SUBUNIT G ISOFORM 1 (OSTEOCLAST-LIKE CELL CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I420023M17 PRODUCT:ATPASE, H+ TRANSPORTING, V1 SUBUNIT G ISOFORM 1, FULL INSERT SEQUENCE) (17 DAYS PREGNANT ADULT FEMALE AMNION CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I920069C17 PRODUCT:ATPASE, H+ TRANSPORTING, V1 SUBUNIT G ISOFORM 1, FULL INSERT SEQUENCE) (G1 ISOFORM OF V-ATPASE SUBUNIT) (16 DAYS EMBRYO HEAD CDNA, RIKEN FULL- LENGTH ENRICHED LIBRARY, CLONE:C130051G04 PRODUCT:ATPASE, H+ TRANSPORTING, LYSOSOMAL (VACUOLAR PROTON PUMP), FULL INSERT SEQUENCE) (2 DAYS NEONATE THYMUS THYMIC CELLS CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:E430024D16 PRODUCT:ATPASE, H+ TRANSPORTING, LYSOSOMAL (VACUOLAR PROTON PUMP), FULL INSERT SEQUENCE) (ATPASE, H+ TRANSPORTING, V1 SUBUNIT G ISOFORM 1);ATPASE, H+ TRANSPORTING, LYSOSOMAL 13KDA, V1 SUBUNIT G ISOFORM 2;ATPASE, H+ TRANSPORTING, LYSOSOMAL 13KDA, V1 SUBUNIT G ISOFORM 2 (FRAGMENT);ATPASE, H+ TRANSPORTING, LYSOSOMAL 13KDA, V1 SUBUNIT G ISOFORM 3;ATPASE, H+ TRANSPORTING, LYSOSOMAL 13KDA, V1 SUBUNIT G ISOFORM 3 (ATPASE, H+ TRANSPORTING, LYSOSOMAL, V1 SUBUNIT G3, ISOFORM A);ATPASE, H+ TRANSPORTING, LYSOSOMAL 13KDA, V1 SUBUNIT G1;ATPASE, H+ TRANSPORTING, LYSOSOMAL 13KDA, V1 SUBUNIT G2;ATPASE, H+ TRANSPORTING, LYSOSOMAL 13KDA, V1 SUBUNIT G3;ATPASE, H+ TRANSPORTING, LYSOSOMAL V1 SUBUNIT G1;ATPASE, H+ TRANSPORTING, LYSOSOMAL V1 SUBUNIT G2;ATPASE, H+ TRANSPORTING, LYSOSOMAL V1 SUBUNIT G3;ATPASE, H+ TRANSPORTING, LYSOSOMAL, V1 SUBUNIT G2 ISOFORM B;ATPASE, H+ TRANSPORTING, LYSOSOMAL, V1 SUBUNIT G3 ISOFORM B;ATPASE, H+ TRANSPORTING, LYSOSOMAL, V1 SUBUNIT G3, ISOFORM A;ATPASE, H+ TRANSPORTING, V1 SUBUNIT G ISOFORM 1;ATPASE, H+ TRANSPORTING, V1 SUBUNIT G, ISOFORM 3;BONE MARROW MACROPHAGE CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I830082M24 PRODUCT:ATPASE, H+ TRANSPORTING, V1 SUBUNIT G ISOFORM 1, FULL INSERT SEQUENCE;G1 ISOFORM OF V-ATPASE SUBUNIT;G2 ISOFORM OF V-ATPASE SUBUNIT;HYPOTHETICAL PROTEIN;OSTEOCLAST-LIKE CELL CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I420023M17 PRODUCT:ATPASE, H+ TRANSPORTING, V1 SUBUNIT G ISOFORM 1, FULL INSERT SEQUENCE;PROTON-TRANSLOCATING ATPASE G SUBUNIT ISOFORM G3;V-ATPASE 13 KDA SUBUNIT 1;V-ATPASE 13 KDA SUBUNIT 2;V-ATPASE 13 KDA SUBUNIT 3;V-ATPASE G SUBUNIT 1;V-ATPASE G SUBUNIT 2;V-ATPASE G SUBUNIT 3;VACUOLAR ATP SYNTHASE SUBUNIT G 1;VACUOLAR ATP SYNTHASE SUBUNIT G 1 (EC 3.6.3.14) (V-ATPASE G SUBUNIT 1) (VACUOLAR PROTON PUMP G SUBUNIT 1) (V-ATPASE 13 KDA SUBUNIT 1);VACUOLAR ATP SYNTHASE SUBUNIT G 1 (EC 3.6.3.14) (V-ATPASE G SUBUNIT 1) (VACUOLAR PROTON PUMP G SUBUNIT 1) (V-ATPASE 13 KDA SUBUNIT 1) (VACUOLAR ATP SYNTHASE SUBUNIT M16);VACUOLAR ATP SYNTHASE SUBUNIT G 2;VACUOLAR ATP SYNTHASE SUBUNIT G 2 (EC 3.6.3.14) (V-ATPASE G SUBUNIT 2) (VACUOLAR PROTON PUMP G SUBUNIT 2) (V-ATPASE 13 KDA SUBUNIT 2);VACUOLAR ATP SYNTHASE SUBUNIT G 3;VACUOLAR ATP SYNTHASE SUBUNIT G 3 (EC 3.6.3.14) (V-ATPASE G SUBUNIT 3) (VACUOLAR PROTON PUMP G SUBUNIT 3) (V-ATPASE 13 KDA SUBUNIT 3);VACUOLAR ATP SYNTHASE SUBUNIT M16;VACUOLAR PROTON PUMP G SUBUNIT 1;VACUOLAR PROTON PUMP G SUBUNIT 2;VACUOLAR PROTON PUMP G SUBUNIT 3 | HSA00190:OXIDATIVE PHOSPHORYLATION;HSA00193:ATP SYNTHESIS;HSA05110:CHOLERA - INFECTION;MMU00190:OXIDATIVE PHOSPHORYLATION;MMU00193:ATP SYNTHESIS | [RefSeq Summary:] This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of a hexamer of three A and three B subunits plus the C, D, and E subunits. It also contains the ATP catalytic site. The encoded protein of this gene is one of three G subunit proteins and associates with the catalytic V1 domain. This gene had the previous gene symbols - ATP6J and ATP6G1. ;[RefSeq Summary:] This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of a hexamer of three A and three B subunits plus the C, D, and E subunits. It also contains the ATP catalytic site. The encoded protein of this gene is one of three G subunit proteins. This gene had the previous gene symbol of ATP6G and ATP6G2. Transcript variants using different 3' splice junctions for the first exon and polyadenylation signals that encode two isoforms have been described. ;[RefSeq Summary:] This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of a hexamer of three A and three B subunits plus the C, D, and E subunits. It also contains the ATP catalytic site. The encoded protein of this gene is one of three G subunit proteins. Transcript variants encoding different isoforms have been found for this gene. |
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LOC666030 |
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LOC671155 |
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LOC671196 |
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Sdpr | 8436 |
| HYPOTHETICAL PROTEIN SDPR;SERUM DEPRIVATION RESPONSE;SERUM DEPRIVATION RESPONSE (HYPOTHETICAL PROTEIN SDPR);SERUM DEPRIVATION RESPONSE (PHOSPHATIDYLSERINE BINDING PROTEIN) |
| [RefSeq Summary:] The protein encoded by this gene is localized in the cytoplasm and binds to phosphatidylserine. It has been identified that this protein is a substrate of protein kinase C, and a major component of caveolae, a plasma membrane invagination. This gene has multiple polyadenylation sites. There might be alternatively spliced transcript variant of this gene but the variant is not fully described yet. |
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Snx6 | 58533 | CELL COMMUNICATION;CELL ORGANIZATION AND BIOGENESIS;CELL SURFACE RECEPTOR LINKED SIGNAL TRANSDUCTION;CELLULAR LOCALIZATION;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY;EPIDERMAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY;ESTABLISHMENT OF CELLULAR LOCALIZATION;ESTABLISHMENT OF LOCALIZATION;ESTABLISHMENT OF PROTEIN LOCALIZATION;INTRACELLULAR PROTEIN TRANSPORT;INTRACELLULAR SIGNALING CASCADE;INTRACELLULAR TRANSPORT;LOCALIZATION;NEGATIVE REGULATION OF BIOLOGICAL PROCESS;NEGATIVE REGULATION OF CELLULAR PROCESS;NEGATIVE REGULATION OF EPIDERMAL GROWTH FACTOR RECEPTOR ACTIVITY;NEGATIVE REGULATION OF SIGNAL TRANSDUCTION;PHYSIOLOGICAL PROCESS;PROTEIN LOCALIZATION;PROTEIN TRANSPORT;REGULATION OF BIOLOGICAL PROCESS;REGULATION OF CELLULAR PROCESS;REGULATION OF EPIDERMAL GROWTH FACTOR RECEPTOR ACTIVITY;REGULATION OF SIGNAL TRANSDUCTION;SIGNAL TRANSDUCTION;TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY;TRANSPORT | FACTOR 2;MSTP010;SORTING NEXIN 6;SORTING NEXIN 6, ISOFORM A;SORTING NEXIN-6;SORTING NEXIN-6 (TRAF4-ASSOCIATED FACTOR 2);TRAF4-ASSOCIATED FACTOR 2 |
| [RefSeq Summary:] This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms. |
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Tapbp | 6892 | ANTIGEN PROCESSING;ANTIGEN PROCESSING, ENDOGENOUS ANTIGEN VIA MHC CLASS I;CELL ORGANIZATION AND BIOGENESIS;CELLULAR LOCALIZATION;CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;DEFENSE RESPONSE;ESTABLISHMENT OF CELLULAR LOCALIZATION;ESTABLISHMENT OF LOCALIZATION;GOLGI VESICLE TRANSPORT;IMMUNE RESPONSE;INTRACELLULAR TRANSPORT;LOCALIZATION;MACROMOLECULE METABOLISM;METABOLISM;ORGANISMAL PHYSIOLOGICAL PROCESS;PEPTIDE ANTIGEN STABILIZATION;PEPTIDE METABOLISM;PEPTIDE STABILIZATION;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;PROTEIN COMPLEX ASSEMBLY;PROTEIN METABOLISM;RESPONSE TO BIOTIC STIMULUS;RESPONSE TO STIMULUS;RETROGRADE VESICLE-MEDIATED TRANSPORT, GOLGI TO ER;SECRETION;SECRETORY PATHWAY;TRANSPORT;VESICLE-MEDIATED TRANSPORT | NGS-17;PROTEIN, TAP-A;TAP BINDING PROTEIN;TAP BINDING PROTEIN (TAPASIN);TAP-ASSOCIATED PROTEIN;TAP-BINDING PROTEIN;TAPASIN;TAPASIN PRECURSOR;TAPASIN PRECURSOR (TPSN) (TPN) (TAP-BINDING PROTEIN) (TAP-ASSOCIATED PROTEIN) (NGS-17);TAPBP PROTEIN;TPN;TPSN | HSA04612:ANTIGEN PROCESSING AND PRESENTATION | [RefSeq Summary:] This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. |
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Cul7 |
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Mfap1 | 4236 |
| MICROFIBRILLAR PROTEIN MFAP1;MICROFIBRILLAR-ASSOCIATED PROTEIN 1 |
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Stt3a |
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Lrrc42 |
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Ptpn23 | 25930 | BIOPOLYMER METABOLISM;BIOPOLYMER MODIFICATION;CELLULAR MACROMOLECULE METABOLISM;CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;CELLULAR PROTEIN METABOLISM;DEPHOSPHORYLATION;MACROMOLECULE METABOLISM;METABOLISM;PHOSPHATE METABOLISM;PHOSPHORUS METABOLISM;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;PROTEIN AMINO ACID DEPHOSPHORYLATION;PROTEIN METABOLISM;PROTEIN MODIFICATION | HD-PTP;HIS-DOMAIN-CONTAINING PROTEIN TYROSINE PHOSPHATASE;HYPOTHETICAL PROTEIN DKFZP564F0923.1;PROTEIN TYROSINE PHOSPHATASE TD14;PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 23;PTP-TD14;TYROSINE PHOSPHATASE TD14;TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 23;TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23;TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23 (EC 3.1.3.48) (HIS- DOMAIN CONTAINING PROTEIN TYROSINE PHOSPHATASE) (HD-PTP) (PROTEIN TYROSINE PHOSPHATASE TD14) (PTP-TD14);TYROSINE-PROTEIN PHOSPHATASE, NON-RECEPTOR TYPE 23 (EC 3.1.3.48) (HIS- DOMAIN CONTAINING PROTEIN TYROSINE PHOSPHATASE) (HD-PTP) (PROTEIN TYROSINE PHOSPHATASE TD14) (PTP-TD14) |
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Qk |
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Taf4b | 6875 | CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;METABOLISM;NUCLEOBASE, NUCLEOSIDE, NUCLEOTIDE AND NUCLEIC ACID METABOLISM;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;REGULATION OF BIOLOGICAL PROCESS;REGULATION OF CELLULAR METABOLISM;REGULATION OF CELLULAR PHYSIOLOGICAL PROCESS;REGULATION OF CELLULAR PROCESS;REGULATION OF METABOLISM;REGULATION OF NUCLEOBASE, NUCLEOSIDE, NUCLEOTIDE AND NUCLEIC ACID METABOLISM;REGULATION OF PHYSIOLOGICAL PROCESS;REGULATION OF TRANSCRIPTION;REGULATION OF TRANSCRIPTION, DNA-DEPENDENT;TRANSCRIPTION;TRANSCRIPTION INITIATION;TRANSCRIPTION, DNA-DEPENDENT | TAF4B RNA POLYMERASE II, TATA BOX BINDING PROTEIN (TBP)-ASSOCIATED FACTOR, 105KDA;TAFII-105;TAFII105;TRANSCRIPTION INITIATION FACTOR TFIID 105 KDA SUBUNIT;TRANSCRIPTION INITIATION FACTOR TFIID 105 KDA SUBUNIT (TAFII-105) (TAFII105) (FRAGMENT) | HSA03022:BASAL TRANSCRIPTION FACTORS | [RefSeq Summary:] TATA-binding protein associated factors (TAFs) participate, with TATA binding protein (TBP; MIM 600075), in the formation of the TFIID protein complex (see MIM 313650), which is involved in the initiation of gene transcription by RNA polymerase II (see MIM 180660).[supplied by OMIM] |
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Zbed3 | 84327 |
| ZINC FINGER BED DOMAIN CONTAINING PROTEIN 3;ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 3;ZINC FINGER, BED DOMAIN CONTAINING 3 VARIANT;ZINC FINGER, BED DOMAIN CONTAINING 3 VARIANT (FRAGMENT);ZINC FINGER, BED-TYPE CONTAINING 3 |
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Sft2d2 |
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Rbak | 57786 | CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;METABOLISM;NUCLEOBASE, NUCLEOSIDE, NUCLEOTIDE AND NUCLEIC ACID METABOLISM;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;REGULATION OF BIOLOGICAL PROCESS;REGULATION OF CELLULAR METABOLISM;REGULATION OF CELLULAR PHYSIOLOGICAL PROCESS;REGULATION OF CELLULAR PROCESS;REGULATION OF METABOLISM;REGULATION OF NUCLEOBASE, NUCLEOSIDE, NUCLEOTIDE AND NUCLEIC ACID METABOLISM;REGULATION OF PHYSIOLOGICAL PROCESS;REGULATION OF TRANSCRIPTION;REGULATION OF TRANSCRIPTION, DNA-DEPENDENT;TRANSCRIPTION;TRANSCRIPTION, DNA-DEPENDENT | HYPOTHETICAL PROTEIN RBAK;RB-ASSOCIATED KRAB REPRESSOR;RB-ASSOCIATED KRAB REPRESSOR (HYPOTHETICAL PROTEIN RBAK) |
| [RefSeq Summary:] This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. |
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Spast |
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Senp2 | 59343 | BIOPOLYMER METABOLISM;BIOPOLYMER MODIFICATION;CELL COMMUNICATION;CELL SURFACE RECEPTOR LINKED SIGNAL TRANSDUCTION;CELLULAR MACROMOLECULE METABOLISM;CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;CELLULAR PROTEIN METABOLISM;MACROMOLECULE METABOLISM;METABOLISM;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;PROTEIN METABOLISM;PROTEIN MODIFICATION;PROTEOLYSIS;REGULATION OF BIOLOGICAL PROCESS;REGULATION OF CELLULAR PROCESS;REGULATION OF SIGNAL TRANSDUCTION;REGULATION OF WNT RECEPTOR SIGNALING PATHWAY;SIGNAL TRANSDUCTION;UBIQUITIN CYCLE;WNT RECEPTOR SIGNALING PATHWAY | AXAM2;SENP2 PROTEIN;SENTRIN-SPECIFIC PROTEASE 2;SENTRIN-SPECIFIC PROTEASE 2 (EC 3.4.22.-) (SENTRIN/SUMO-SPECIFIC PROTEASE SENP2) (SMT3-SPECIFIC ISOPEPTIDASE 2) (SMT3IP2) (AXAM2);SENTRIN/SUMO-SPECIFIC PROTEASE SENP2;SMT3-SPECIFIC ISOPEPTIDASE 2;SMT3IP2;SUMO1/SENTRIN/SMT3 SPECIFIC PEPTIDASE 2;SUMO1/SENTRIN/SMT3 SPECIFIC PROTEASE 2 | HSA04310:WNT SIGNALING PATHWAY |
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Zfp275 |
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Sytl2 | 54843 | CELL ORGANIZATION AND BIOGENESIS;CELLULAR LOCALIZATION;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;ESTABLISHMENT OF CELLULAR LOCALIZATION;ESTABLISHMENT OF LOCALIZATION;ESTABLISHMENT OF PROTEIN LOCALIZATION;INTRACELLULAR PROTEIN TRANSPORT;INTRACELLULAR TRANSPORT;LOCALIZATION;PHYSIOLOGICAL PROCESS;PROTEIN LOCALIZATION;PROTEIN TRANSPORT;TRANSPORT;VESICLE-MEDIATED TRANSPORT | BREAST CANCER-ASSOCIATED ANTIGEN SGA-72M;CDNA FLJ16407 FIS, CLONE UTERU2028734, HIGHLY SIMILAR TO MUS MUSCULUS SLP2-A SYNAPTOTAGMIN-LIKE PROTEIN 2-A DELTA 2S-III;CDNA FLJ42764 FIS, CLONE BRAWH3002821, MODERATELY SIMILAR TO MUS MUSCULUS SYNAPTOTAGMIN-LIKE 2;CDNA FLJ45597 FIS, CLONE BRTHA3018409, WEAKLY SIMILAR TO MUS MUSCULUS SYNAPTOTAGMIN-LIKE 4;CHR11 SYNAPTOTAMIN;CHR11 SYNAPTOTAMIN (FRAGMENT);EXOPHILIN-4;HYPOTHETICAL PROTEIN;HYPOTHETICAL PROTEIN FLJ16407;HYPOTHETICAL PROTEIN FLJ42764;HYPOTHETICAL PROTEIN FLJ45597;SYNAPTOTAGMIN-LIKE 2;SYNAPTOTAGMIN-LIKE 2 ISOFORM A;SYNAPTOTAGMIN-LIKE 2 ISOFORM B;SYNAPTOTAGMIN-LIKE 2 ISOFORM C;SYNAPTOTAGMIN-LIKE 2 ISOFORM D;SYNAPTOTAGMIN-LIKE 2 ISOFORM E VARIANT;SYNAPTOTAGMIN-LIKE 2 ISOFORM E VARIANT (FRAGMENT);SYNAPTOTAGMIN-LIKE 2 ISOFORM F;SYNAPTOTAGMIN-LIKE PROTEIN 2;SYNAPTOTAGMIN-LIKE PROTEIN 2 (EXOPHILIN-4);SYTL2;SYTL4 |
| [RefSeq Summary:] The protein encoded by this gene is a synaptotagmin-like protein of the C2 domain-containing family of proteins. The protein contains two carboxyl-terminal Ca2+-binding motifs (C2 domains). Found in phospholipases and protein kinase C, C2 domains have also been identified in synaptotagmins, a family of proteins involved in regulating neurotransmission. Although the specific function of the synaptotagmin-like proteins is unknown, a role in regulation of synaptic vesicle trafficking via their C2 domains has been suggested. Alternative splicing occurs at this locus and two variants have been identified. Additional splice variants have been suggested but supporting sequence confirmation is not yet available. |
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Hkr2 | 342945 | BIOLOGICAL PROCESS UNKNOWN;CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;METABOLISM;NUCLEOBASE, NUCLEOSIDE, NUCLEOTIDE AND NUCLEIC ACID METABOLISM;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;REGULATION OF BIOLOGICAL PROCESS;REGULATION OF CELLULAR METABOLISM;REGULATION OF CELLULAR PHYSIOLOGICAL PROCESS;REGULATION OF CELLULAR PROCESS;REGULATION OF METABOLISM;REGULATION OF NUCLEOBASE, NUCLEOSIDE, NUCLEOTIDE AND NUCLEIC ACID METABOLISM;REGULATION OF PHYSIOLOGICAL PROCESS;REGULATION OF TRANSCRIPTION;REGULATION OF TRANSCRIPTION, DNA-DEPENDENT;TRANSCRIPTION;TRANSCRIPTION, DNA-DEPENDENT | DNA-BINDING PROTEIN;DNA-BINDING PROTEIN (FRAGMENT);FINGER PROTEIN ZNF50;GLI-KRUPPEL FAMILY MEMBER HKR2;GLI-RELATED FINGER PROTEIN HKR2;HKR2 PROTEIN;HYPOTHETICAL PROTEIN DKFZP686P21111;HYPOTHETICAL PROTEIN DKFZP686P21111 (HYPOTHETICAL PROTEIN FLJ46883);HYPOTHETICAL PROTEIN FLJ46883;KRUEPPEL-RELATED ZINC FINGER PROTEIN 2;KRUEPPEL-RELATED ZINC FINGER PROTEIN 2 (HKR2 PROTEIN) (ZINC FINGER PROTEIN 50) (ZINC FINGER AND SCAN DOMAIN CONTAINING PROTEIN 22) (FRAGMENT);ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 22;ZINC FINGER PROTEIN 50 |
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Dpep1 | 1800 | CELLULAR MACROMOLECULE METABOLISM;CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;CELLULAR PROTEIN METABOLISM;MACROMOLECULE METABOLISM;METABOLISM;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;PROTEIN METABOLISM;PROTEOLYSIS | DEHYDROPEPTIDASE-I;DIPEPTIDASE 1 (RENAL);DPEP1 PROTEIN;MDP;MEMBRANE DIPEPTIDASE (EC 3.4.13.19) PRECURSOR ALT_NAMES:DEHYDROPEPTIDASE-I; RENAL DIPEPTIDASE;MICROSOMAL DIPEPTIDASE PRECURSOR;MICROSOMAL DIPEPTIDASE PRECURSOR (EC 3.4.13.19) (MDP) (DEHYDROPEPTIDASE-I) (RENAL DIPEPTIDASE) (RDP);PRECURSOR;RDP;RENAL DIPEPTIDASE |
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Pfkfb2 | 5208 | ALCOHOL CATABOLISM;ALCOHOL METABOLISM;CARBOHYDRATE CATABOLISM;CARBOHYDRATE METABOLISM;CATABOLISM;CELLULAR CARBOHYDRATE CATABOLISM;CELLULAR CARBOHYDRATE METABOLISM;CELLULAR CATABOLISM;CELLULAR MACROMOLECULE CATABOLISM;CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;FRUCTOSE 2,6-BISPHOSPHATE METABOLISM;FRUCTOSE METABOLISM;GENERATION OF PRECURSOR METABOLITES AND ENERGY;GLUCOSE CATABOLISM;GLUCOSE METABOLISM;GLYCOLYSIS;HEXOSE CATABOLISM;HEXOSE METABOLISM;MACROMOLECULE CATABOLISM;MACROMOLECULE METABOLISM;METABOLISM;MONOSACCHARIDE CATABOLISM;MONOSACCHARIDE METABOLISM;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;REGULATION OF BIOLOGICAL PROCESS;REGULATION OF CATABOLISM;REGULATION OF GLYCOLYSIS;REGULATION OF METABOLISM;REGULATION OF PHYSIOLOGICAL PROCESS | 17 DAYS EMBRYO STOMACH CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I920049D20 PRODUCT:6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BIPHOSPHATASE 2, FULL INSERT SEQUENCE;2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE;6-BISPHOSPHATASE;6-PHOSPHOFRUCTO-2-KINASE (EC 2.7.1.105) / FRUCTOSE-2,6-BISPHOSPHATE 2-PHOSPHATASE (EC 3.1.3.46);6-PHOSPHOFRUCTO-2-KINASE (EC 2.7.1.105) / FRUCTOSE-2,6-BISPHOSPHATE 2-PHOSPHATASE (EC 3.1.3.46) ALT_NAMES:FRU6P2-KINASE/FRU2,6BPASE;6-PHOSPHOFRUCTO-2-KINASE (EC 2.7.1.105) / FRUCTOSE-2,6-BISPHOSPHATE 2-PHOSPHATASE (EC 3.1.3.46), BRAIN;6-PHOSPHOFRUCTO-2-KINASE (EC 2.7.1.105) / FRUCTOSE-2,6-BISPHOSPHATE 2-PHOSPHATASE (EC 3.1.3.46), BRAIN ALT_NAMES:FRUCTOSE 6-PHOSPHATE, 2-KINASE-FRUCTOSE 2,6-BISPHOSPHATASE;6-PHOSPHOFRUCTO-2-KINASE (EC 2.7.1.105) / FRUCTOSE-2,6-BISPHOSPHATE 2-PHOSPHATASE (EC 3.1.3.46), HEPATIC;6-PHOSPHOFRUCTO-2-KINASE (EC 2.7.1.105) / FRUCTOSE-2,6-BISPHOSPHATE 2-PHOSPHATASE (EC 3.1.3.46), HEPATIC ALT_NAMES:6-PHOSPHOFRUCTO-2-KINASE / FRUCTOSE-2,6-BISPHOSPHATASE, HEPATIC CONTAINS:6-PHOSPHOFRUCTO-2-KINASE (EC 2.7.1.105); FRUCTOSE-2,6-BISPHOSPHATE 2-PHOSPHATASE (EC 3.1.3.46);6-PHOSPHOFRUCTO-2-KINASE (EC 2.7.1.105) / FRUCTOSE-2,6-BISPHOSPHATE 2-PHOSPHATASE (EC 3.1.3.46), HEPATIC ALT_NAMES:FRUCTOSE-2,6-BISPHOSPHATASE, HEPATIC CONTAINS:6-PHOSPHOFRUCTO-2-KINASE (EC 2.7.1.105); FRUCTOSE-2,6-BISPHOSPHATE 2-PHOSPHATASE (EC 3.1.3.46);6-PHOSPHOFRUCTO-2-KINASE (EC 2.7.1.105) / FRUCTOSE-2,6-BISPHOSPHATE 2-PHOSPHATASE (EC 3.1.3.46), TESTIS ALT_NAMES:PHOSPHOFRUCTOKINASE 2/FRUCTOSE-2,6-BISPHOSPHATASE;6-PHOSPHOFRUCTO-2-KINASE/ FRUCTOSE-2,6-BISPHOSPHATASE;6-PHOSPHOFRUCTO-2-KINASE/ FRUCTOSE-2,6-BISPHOSPHATASE (EC 2.7.1.105) (FRAGMENT);6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE 2,6-BISPHOSPHATASE;6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2, 6-BIPHOSPHATASE 1;6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2, 6-BIPHOSPHATASE 2;6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2, 6-BIPHOSPHATASE 2 (17 DAYS EMBRYO STOMACH CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I920049D20 PRODUCT:6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BIPHOSPHATASE 2, FULL INSERT SEQUENCE);6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2, 6-BIPHOSPHATASE 2, ISOFORM A;6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2, 6-BIPHOSPHATASE 4 ISOFORM 1;6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2, 6-BIPHOSPHATASE 4 ISOFORM 1 (EC 2.7.1.105) (EC 3.1.3.46);6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2, 6-BIPHOSPHATASE 4 SPLICE ISOFORM 3;6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2, 6-BIPHOSPHATASE 4 SPLICE ISOFORM 4;6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2, 6-BIPHOSPHATASE 4 SPLICE ISOFORM 4 (EC 3.1.3.46) (EC 2.7.1.105);6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2, 6-BIPHOSPHATASE 4 SPLICE ISOFORM 5;6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2, 6-BIPHOSPHATASE 4 SPLICE ISOFORM 5 (EC 3.1.3.46) (EC 2.7.1.105);6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2, 6-BIPHOSPHATASE-4 ISOFORM 2;6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2, 6-BIPHOSPHATASE-4 ISOFORM 2 (EC 3.1.3.46) (6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2, 6-BIPHOSPHATASE 4 SPLICE ISOFORM 3) (EC 2.7.1.105);6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2, 6-BISPHOSPHATASE 1;6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2, 6-BISPHOSPHATASE 1 (EC 2.7.1.105) (EC 3.1.3.46) (FRAGMENT);6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BIPHOSPHAT ASE 3;6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BIPHOSPHAT ASE 3 (6- PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2, 6-BISPHOSPHATASE) (EC 3.1.3.46);6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BIPHOSPHAT ASE 3 (6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2, 6-BISPHOSPHATASE);6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BIPHOSPHATA SE 2;6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BIPHOSPHATASE 1;6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BIPHOSPHATASE 1 (6PF-2-K/FRU- 2,6-P2ASE LIVER ISOZYME) [INCLUDES: 6-PHOSPHOFRUCTO-2-KINASE (EC 2.7.1.105); FRUCTOSE-2,6-BISPHOSPHATASE (EC 3.1.3.46)];6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BIPHOSPHATASE 2;6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BIPHOSPHATASE 2 (6PF-2-K/FRU- 2,6-P2ASE HEART-TYPE ISOZYME) (PFK-2/FBPASE-2) (RH2K) [INCLUDES: 6- PHOSPHOFRUCTO-2-KINASE (EC 2.7.1.105); FRUCTOSE-2,6-BISPHOSPHATASE (EC 3.1.3.46)];6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BIPHOSPHATASE 2 (6PF-2-K/FRU- 2,6-P2ASE HEART-TYPE ISOZYME) (PFK-2/FBPASE-2) [INCLUDES: 6- PHOSPHOFRUCTO-2-KINASE (EC 2.7.1.105); FRUCTOSE-2,6-BISPHOSPHATASE (EC 3.1.3.46)];6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BIPHOSPHATASE 3;6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BIPHOSPHATASE 3 (6PF-2-K/FRU- 2,6-P2ASE BRAIN-TYPE ISOZYME) (RB2K) [INCLUDES: 6-PHOSPHOFRUCTO-2- KINASE (EC 2.7.1.105); FRUCTOSE-2,6-BISPHOSPHATASE (EC 3.1.3.46)];6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BIPHOSPHATASE 3 (6PF-2-K/FRU- 2,6-P2ASE BRAIN/PLACENTA-TYPE ISOZYME) (IPFK-2) [INCLUDES: 6- PHOSPHOFRUCTO-2-KINASE (EC 2.7.1.105); FRUCTOSE-2,6-BISPHOSPHATASE (EC 3.1.3.46)];6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BIPHOSPHATASE 4;6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BIPHOSPHATASE 4 (6PF-2-K/FRU- 2,6-P2ASE TESTIS-TYPE ISOZYME) [INCLUDES: 6-PHOSPHOFRUCTO-2-KINASE (EC 2.7.1.105); FRUCTOSE-2,6-BISPHOSPHATASE (EC 3.1.3.46)];6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 2 (HEART);6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 2 ISOFORM B;6-PHOSPHOFRUCTO-2-KINASE\/FRUCTOSE-2,6-BIPHOSPHAT ASE 1;6-PHOSPHOFRUCTO-2-KINASE\/FRUCTOSE-2,6-BIPHOSPHAT ASE 1 (6- PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2, 6-BIPHOSPHATASE 1);6PF-2-K/FRU-2,6-P2ASE BRAIN-TYPE ISOZYME;6PF-2-K/FRU-2,6-P2ASE BRAIN/PLACENTA-TYPE ISOZYME;6PF-2-K/FRU-2,6-P2ASE HEART-TYPE ISOZYME;6PF-2-K/FRU-2,6-P2ASE LIVER ISOZYME;6PF-2-K/FRU-2,6-P2ASE TESTIS-TYPE ISOZYME;ADULT MALE TESTIS CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:4930432D09 PRODUCT:6-PHOSPHOFRUCTO-2-KINASE/ FRUCTOSE-2,6- BIPHOSPHATASE 2, FULL INSERT SEQUENCE;ADULT MALE TESTIS CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:4930432D09 PRODUCT:6-PHOSPHOFRUCTO-2-KINASE/ FRUCTOSE-2,6-BIPHOSPHATASE 2, FULL INSERT SEQUENCE;CDNA FLJ16284 FIS, CLONE NTONG2008093, HIGHLY SIMILAR TO 6PF-2-K/FRU-2,6-P2ASE BRAIN/PLACENTA-TYPE ISOZYME;FRUCTOSE 6-PHOSPHATE 2-KINASE/FRUCTOSE 2,6-BISPHOSPHATASE;FRUCTOSE 6-PHOSPHATE 2-KINASE/FRUCTOSE 2,6-BISPHOSPHATASE (FRAGMENT);FRUCTOSE-2, 6-BISPHOSPHATASSE;FRUCTOSE-6-PHOSPHATE,2-KINASE/FRUCTOSE-2, 6-BISPHOSPHATASE;FRUCTOSE-6-PHOSPHATE,2-KINASE/FRUCTOSE-2, 6-BISPHOSPHATASE (FRAGMENT);HYPOTHETICAL PROTEIN DKFZP781D2217;HYPOTHETICAL PROTEIN FLJ16284;INDUCIBLE 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE;INDUCIBLE 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE (EC 2.7.1.105) (EC 3.1.3.46) (FRAGMENT);IPFK-2;PFK-2/FBPASE-2;RAT 6-PHOSPHOFRUCTO 2-KINASE/FRUCTOSE 2,6-BISPHOSPHATASE;RAT 6-PHOSPHOFRUCTO 2-KINASE/FRUCTOSE 2,6-BISPHOSPHATASE (FRAGMENT);RB2K;RH2K;RIKEN CDNA 4930568D07 GENE;TESTIS PFKFB4 | HSA00051:FRUCTOSE AND MANNOSE METABOLISM;MMU00051:FRUCTOSE AND MANNOSE METABOLISM;RNO00051:FRUCTOSE AND MANNOSE METABOLISM |
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Ssbp1 | 6742 | BIOPOLYMER METABOLISM;CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;DNA METABOLISM;DNA REPLICATION;MACROMOLECULE METABOLISM;METABOLISM;NUCLEOBASE, NUCLEOSIDE, NUCLEOTIDE AND NUCLEIC ACID METABOLISM;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM | HYPOTHETICAL PROTEIN SSBP1;HYPOTHETICAL PROTEIN SSBP1 (FRAGMENT);MT-SSB;MTSSB;PWP1-INTERACTING PROTEIN 17;SINGLE-STRANDED DNA BINDING PROTEIN 1;SINGLE-STRANDED DNA-BINDING PROTEIN, MITOCHONDRIAL PRECURSOR;SINGLE-STRANDED DNA-BINDING PROTEIN, MITOCHONDRIAL PRECURSOR (MT-SSB) (MTSSB) (PWP1-INTERACTING PROTEIN 17);SINGLE-STRANDED MITOCHONDRIAL DNA-BINDING PROTEIN PRECURSOR ALT_NAMES:HELIX-DESTABILIZING PROTEIN;SSBP1 PROTEIN;SSBP1 PROTEIN (FRAGMENT) |
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Recql | 5965 | BIOPOLYMER METABOLISM;CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;DNA METABOLISM;DNA REPAIR;MACROMOLECULE METABOLISM;METABOLISM;NUCLEOBASE, NUCLEOSIDE, NUCLEOTIDE AND NUCLEIC ACID METABOLISM;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;RESPONSE TO DNA DAMAGE STIMULUS;RESPONSE TO ENDOGENOUS STIMULUS;RESPONSE TO STIMULUS;RESPONSE TO STRESS | ATP-DEPENDENT DNA HELICASE Q1;ATP-DEPENDENT DNA HELICASE Q1 (DNA-DEPENDENT ATPASE Q1);DNA HELICASE RECQL;DNA HELICASE RECQL ALT_NAMES:RECQ HELICASE HOMOLOG;DNA-DEPENDENT ATPASE Q1;HELICASE ISOFORM;HELICASE Q1;RECQ PROTEIN-LIKE (DNA HELICASE Q1-LIKE);RECQ PROTEIN-LIKE ISOFORM 1 |
| [RefSeq Summary:] The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5' and 3' UTRs, have been described. |
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Brms1 | 0 |
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Vldlr | 7436 | ALCOHOL METABOLISM;BEHAVIOR;CARBOXYLIC ACID METABOLISM;CELL COMMUNICATION;CELLULAR LIPID METABOLISM;CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;CHOLESTEROL METABOLISM;DEVELOPMENT;ENDOCYTOSIS;ESTABLISHMENT OF LOCALIZATION;FATTY ACID METABOLISM;LEARNING AND/OR MEMORY;LIPID METABOLISM;LIPID TRANSPORT;LOCALIZATION;MEMORY;METABOLISM;NERVOUS SYSTEM DEVELOPMENT;ORGANIC ACID METABOLISM;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;RESPONSE TO STIMULUS;SIGNAL TRANSDUCTION;STEROID METABOLISM;STEROL METABOLISM;SYSTEM DEVELOPMENT;TRANSPORT;VESICLE-MEDIATED TRANSPORT | HYPOTHETICAL PROTEIN FLJ35062;HYPOTHETICAL PROTEIN FLJ35062 (VERY LOW DENSITY LIPOPROTEIN RECEPTOR);LOW DENSITY LIPOPROTEIN RECEPTOR;VERY LOW DENSITY LIPOPROTEIN RECEPTOR;VERY LOW-DENSITY LIPOPROTEIN RECEPTOR PRECURSOR;VERY LOW-DENSITY LIPOPROTEIN RECEPTOR PRECURSOR (VLDL RECEPTOR);VERY LOW-DENSITY LIPOPROTEIN RECEPTOR VARIANT;VERY LOW-DENSITY LIPOPROTEIN RECEPTOR VARIANT (FRAGMENT);VLDL RECEPTOR;VLDL RECEPTOR PRECURSOR, LONG SPLICE FORM ALT_NAMES:VERY LOW DENSITY LIPOPROTEIN RECEPTOR; VITELLOGENIN RECEPTOR CONTAINS:VLDL RECEPTOR SHORT SPLICE FORM;VLDL-R |
| [Proteome Summary:] Very low density lipoprotein receptor; required for proper development of the cerebral cortex and cerebellum; very strongly similar to murine Vldlr |
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Mdh1 | 4190 | ACETYL-COA CATABOLISM;ACETYL-COA METABOLISM;AEROBIC RESPIRATION;ALCOHOL CATABOLISM;ALCOHOL METABOLISM;BIOLOGICAL PROCESS UNKNOWN;CARBOHYDRATE CATABOLISM;CARBOHYDRATE METABOLISM;CARBOXYLIC ACID METABOLISM;CATABOLISM;CELLULAR CARBOHYDRATE CATABOLISM;CELLULAR CARBOHYDRATE METABOLISM;CELLULAR CATABOLISM;CELLULAR MACROMOLECULE CATABOLISM;CELLULAR METABOLISM;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;CELLULAR RESPIRATION;COENZYME CATABOLISM;COENZYME METABOLISM;COFACTOR CATABOLISM;COFACTOR METABOLISM;GENERATION OF PRECURSOR METABOLITES AND ENERGY;GLUCOSE CATABOLISM;GLUCOSE METABOLISM;GLYCOLYSIS;HEXOSE CATABOLISM;HEXOSE METABOLISM;MACROMOLECULE CATABOLISM;MACROMOLECULE METABOLISM;MALATE METABOLISM;METABOLISM;MONOSACCHARIDE CATABOLISM;MONOSACCHARIDE METABOLISM;ORGANIC ACID METABOLISM;PHYSIOLOGICAL PROCESS;PRIMARY METABOLISM;TRICARBOXYLIC ACID CYCLE;TRICARBOXYLIC ACID CYCLE INTERMEDIATE METABOLISM | 10 DAYS LACTATION, ADULT FEMALE MAMMARY GLAND CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:D730032C02 PRODUCT:MALATE DEHYDROGENASE 1, NAD (SOLUBLE), FULL INSERT SEQUENCE;ADULT MALE CEREBELLUM CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:1500012M15 PRODUCT:MALATE DEHYDROGENASE, SOLUBLE, FULL INSERT SEQUENCE;CYTOPLASMIC MALATE DEHYDROGENASE;CYTOPLASMIC MALATE DEHYDROGENASE (FRAGMENT);CYTOSOLIC MALATE DEHYDROGENASE;HYPOTHETICAL PROTEIN MDH1;HYPOTHETICAL PROTEIN MDH2;HYPOTHETICAL PROTEIN MDH2 (FRAGMENT);MALATE DEHYDROGENASE;MALATE DEHYDROGENASE (EC 1.1.1.37) PRECURSOR, MITOCHONDRIAL;MALATE DEHYDROGENASE (EC 1.1.1.37), CYTOSOLIC;MALATE DEHYDROGENASE 1, NAD (MALATE DEHYDROGENASE, SOLUBLE) (17 DAYS EMBRYO STOMACH CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:I920030L07 PRODUCT:MALATE DEHYDROGENASE 1, NAD (SOLUBLE), FULL INSERT SEQUENCE);MALATE DEHYDROGENASE 1, NAD (SOLUBLE);MALATE DEHYDROGENASE 2, NAD (MITOCHONDRIAL);MALATE DEHYDROGENASE, CYTOPLASMIC;MALATE DEHYDROGENASE, CYTOPLASMIC (EC 1.1.1.37);MALATE DEHYDROGENASE, MITOCHONDRIAL;MALATE DEHYDROGENASE, MITOCHONDRIAL PRECURSOR;MALATE DEHYDROGENASE, MITOCHONDRIAL PRECURSOR (EC 1.1.1.37);MALATE DEHYDROGENASE, SOLUBLE;MALATE DEHYDROGENASE, SOLUBLE (FRAGMENT);MDH2 PROTEIN;MITOCHONDRIAL MALATE DEHYDROGENASE PRECURSOR | HSA00020:CITRATE CYCLE (TCA CYCLE);HSA00620:PYRUVATE METABOLISM;HSA00630:GLYOXYLATE AND DICARBOXYLATE METABOLISM;HSA00710:CARBON FIXATION;HSA00720:REDUCTIVE CARBOXYLATE CYCLE (CO2 FIXATION);MMU00020:CITRATE CYCLE (TCA CYCLE);MMU00620:PYRUVATE METABOLISM;MMU00630:GLYOXYLATE AND DICARBOXYLATE METABOLISM;MMU00710:CARBON FIXATION;MMU00720:REDUCTIVE CARBOXYLATE CYCLE (CO2 FIXATION);RNO00020:CITRATE CYCLE (TCA CYCLE);RNO00620:PYRUVATE METABOLISM;RNO00630:GLYOXYLATE AND DICARBOXYLATE METABOLISM;RNO00710:CARBON FIXATION;RNO00720:REDUCTIVE CARBOXYLATE CYCLE (CO2 FIXATION) | [RefSeq Summary:] Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. ;[RefSeq Summary:] Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. |
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Pnrc2 |
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Pacs1 | 55690 |
| HYPOTHETICAL PROTEIN DKFZP434H1014;HYPOTHETICAL PROTEIN DKFZP434H1014 (FRAGMENT);HYPOTHETICAL PROTEIN DKFZP434H1014.1;PACS-1;PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN 1;PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN 1 (PACS-1);SORTING CONNECTOR |
| [RefSeq Summary:] This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. |
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Itgal | 3683 | CELL ADHESION;CELL COMMUNICATION;CELL MOTILITY;CELL SURFACE RECEPTOR LINKED SIGNAL TRANSDUCTION;CELLULAR PHYSIOLOGICAL PROCESS;CELLULAR PROCESS;DEFENSE RESPONSE;ESTABLISHMENT OF LOCALIZATION;IMMUNE RESPONSE;INFLAMMATORY RESPONSE;INTEGRIN-MEDIATED SIGNALING PATHWAY;LOCALIZATION;LOCALIZATION OF CELL;LOCOMOTION;ORGANISMAL PHYSIOLOGICAL PROCESS;PHYSIOLOGICAL PROCESS;RESPONSE TO BIOTIC STIMULUS;RESPONSE TO EXTERNAL STIMULUS;RESPONSE TO OTHER ORGANISM;RESPONSE TO PEST, PATHOGEN OR PARASITE;RESPONSE TO STIMULUS;RESPONSE TO STRESS;RESPONSE TO WOUNDING;SIGNAL TRANSDUCTION | CD11A ANTIGEN;CELL SURFACE GLYCOPROTEIN CD11A PRECURSOR;CELL SURFACE GLYCOPROTEIN CD11A PRECURSOR ALT_NAMES:LEUKOCYTE ADHESION GLYCOPROTEIN LFA-1 ALPHA CHAIN; LEUKOCYTE FUNCTION ASSOCIATED ANTIGEN 1 ALPHA CHAIN;FUNCTION-ASSOCIATED ANTIGEN 1;FUNCTION-ASSOCIATED MOLECULE-1 ALPHA SUBUNIT;INTEGRIN ALPHA-L PRECURSOR;INTEGRIN ALPHA-L PRECURSOR (LEUKOCYTE ADHESION GLYCOPROTEIN LFA-1 ALPHA CHAIN) (LFA-1A) (LEUKOCYTE FUNCTION ASSOCIATED MOLECULE 1, ALPHA CHAIN) (CD11A);INTEGRIN, ALPHA L (ANTIGEN CD11A (P180), LYMPHOCYTE FUNCTION- ASSOCIATED ANTIGEN 1; ALPHA POLYPEPTIDE);INTEGRIN, ALPHA L (ANTIGEN CD11A (P180), LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 1; ALPHA POLYPEPTIDE);ITGAL PROTEIN;LEUKOCYTE ADHESION GLYCOPROTEIN LFA-1 ALPHA CHAIN;LEUKOCYTE FUNCTION-ASSOCIATED MOLECULE 1 ALPHA CHAIN;LFA-1A | HSA04514:CELL ADHESION MOLECULES (CAMS);HSA04650:NATURAL KILLER CELL MEDIATED CYTOTOXICITY;HSA04670:LEUKOCYTE TRANSENDOTHELIAL MIGRATION;HSA04810:REGULATION OF ACTIN CYTOSKELETON | [RefSeq Summary:] ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. |
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LOC671163 |
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