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Video 3 (5.8MB)
A CeCENP-C-depleted embryo expressing GFP-histone corresponding to the still images in the right column of Fig. 2. The maternal nucleus is initially on the left and the paternal nucleus on the right. Paired DIC/GFP images were acquired every 7 s; playback rate is 12 frames/s. The chromosomes fail to distribute over the metaphase plate and chromosome segregation at anaphase completely fails.