Locus-specific and activity-independent gene repositioning during early tumorigenesis -- Data Supplement - JCB--Meaburn et al. -- The Journal of Cell Biology

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Figure S1. Radial distribution of genes during differentiation of mammary epithelial cells and early tumorigenesis. Gene loci were detected in PFA-fixed cells using specific BAC FISH probes. (A–K) Histograms to quantify the normalized radial distribution (RRD) for each gene in MCF-10.B2 cells, proliferating 2D culture nuclei (Day 0), and after growth for 20 d under 3D culture conditions with 10 d of constitutive activation of ErbB2 (Day 20, ErbB2) or without activation (Day 20) and in quiescent 2D cultures (quiescent). P(RRD) denotes the probability associated with a loci being at a particular RRD. n = 195–220 per BAC per growth condition.