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Diagnostic performance of low C4, low C1inhA/C1inhF for hereditary angio-oedema (HAE) in untreated patients.
| Low C4 (< 0.14 g/l) | C1inhA (< 150 mg/l) | C1inhF (m = manufacturers' range, < 68%) | C1inhF (optimized range, < 84%) | Low C4 and low C1inhF (optimized range) | |
|---|---|---|---|---|---|
| Sensitivity | 81% | 97%* | 57% | 78% | 78%* |
| Specificity | 85% | 100%* | 100% | 100% | 100%* |
Refers to HAE type I.
