Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid -- Data Supplement - -- Proceedings of the National Academy of Sciences

Supplementary material for Calhoun et al. (1999) Proc. Natl. Acad. Sci. USA 96 (24), 14088-14093.

Fig. 8.
Amyloid deposition in APP23 mice on an App-null background. In mice lacking endogenous APP, the production of transgenic human APP alone was sufficient to induce both vascular amyloid and plaques. A view of neocortex from an 18-month-old mouse is shown stained for Aß (brown) and counterstained with cresyl-violet (blue). (Bar = 15 µm.)