© 2000-2007 Ingenuity Systems, Inc. All rights reserved. Name Synonyms Description Affymetrix Location Family Drugs Entrez Gene ID for Human Entrez Gene ID for Mouse Entrez Gene ID for Rat AACS 2210408B16Rik, Acetoacetyl-coa synthetase, FLJ12389, FLJ41251, SUR-5 acetoacetyl-CoA synthetase 218434_s_at Cytoplasm enzyme 65985 78894 65984 AARS AI316495, Alanine--tRNA ligase, ALANYL-TRNA SYNTHETASE, ALARS, C76919, MGC37368, sti alanyl-tRNA synthetase 201000_at Cytoplasm enzyme 16 234734 292023 ACTL6A 2810432C06Rik, Actin-like 6a, ACTL6, AI851094, ARP4, BAF53, BAF53A, C79802, MGC112664, MGC5382, RGD1307747 actin-like 6A 202666_s_at Nucleus other 86 56456 361925 ADD3 35H, ADDL, AI463285, Gamma adducin, R75380 adducin 3 (gamma) 201753_s_at Cytoplasm other 120 27360 25230 AK2 ADK2, D4Ertd220e adenylate kinase 2 212173_at Cytoplasm kinase 204 11637 24184 AKR7A2 0610025K21Rik, 2-Cba Reductase, AFAR, AFAR1, AFB1-AR1, Aiar, AKR7, Akr7a5 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 202139_at Cytoplasm enzyme 8574 110198 171445 Aspartate-tRNA ligase aspartyl-tRNA synthetase, L-aspartate:tRNAAsp ligase (AMP-forming) Unknown group ATPIF1 ATPI, ATPIP, IF1, IF1PA, IP, MGC1167, MGC8898, Urinary protein 2 ATPase inhibitory factor 1 218671_s_at Cytoplasm other 93974 11983 25392 BOP1 AU020183, AW146150, D18861, Erb1p, KIAA0124, MGC109114, mKIAA0124 block of proliferation 1 212563_at Nucleus other 23246 12181 300050 C1ORF2 1110013L07Rik, cote 1, RGD1306107_predicted chromosome 1 open reading frame 2 203550_s_at Unknown other 10712 68521 310640 CAPN3 AI323605, Calpain 3, CANP3, CANPL3, Capa-3, LGMD2, LGMD2A, Lp82, Lp84, Lp85, M calpain, MGC10767, MGC11121, MGC14344, MGC4403, nCL-1, p94 calpain 3, (p94) 214475_x_at Cytoplasm peptidase 825 12335 29155 CBX3 HECH, HP1-GAMMA, HP1G, HP1Hs-gamma, M32, MGC105792, MGC105793, MGC118084, MGC156678, MGC94711 chromobox homolog 3 (HP1 gamma homolog, Drosophila) 200037_s_at Nucleus other 11335 12417 297093 CDCA7 2310021G01Rik, AU044109, FLJ14722, FLJ14736, JPO1, MGC112656, MGC34109 cell division cycle associated 7 224428_s_at Nucleus other 83879 66953 311742 CDCA7L BC006933, DKFZp762L0311, JPO2, LOC619566, MGC11998, R1, RAM2 cell division cycle associated 7-like 225081_s_at Nucleus other 55536 217946 619566 CHKA Chetk-alpha, CHK, ChoK, CHOLINE KINASE, CK-R, CKI, EtnK-alpha, MGC93538 choline kinase alpha 204233_s_at Cytoplasm kinase 1119 12660 29194 Creb Creb protein Unknown group CTBS 2210401K11Rik, CTB, DTBS, Image:789813 chitobiase, di-N-acetyl- 218923_at Cytoplasm enzyme 1486 74245 81652 DARS 5730439G15Rik, ASPARTYL-TRNA SYNTHETASE, ASPRS, DKFZp781B11202, DRS, DRS1, MGC111579 aspartyl-tRNA synthetase 201624_at Cytoplasm enzyme 1615 226414 116483 DARS2 5830468K18Rik, Asp synthetase, Aspartyl-tRNA Synthetase 2, ASPRS, ASPRS. LBSL, FLJ10514, MGC124683, MGC99963, RGD1308286, RP3-383J4.2 aspartyl-tRNA synthetase 2, mitochondrial 218365_s_at Unknown enzyme 55157 226539 304919 EHHADH 1300002P22Rik, Bien, Bif, BIFUNCTIONAL ENZYME, ECHD, Enoyl-coa hydratase-l-3-hydroxyacyl-coa dehydrogenase, Had, HD, L-PBE, L-Specific Multifunctional Beta Oxidation Protein, LBFP, LBP, Lmbop, MFP, MFP1, MGC120586, Pbe, PBFE, perMFE-1, Peroxisomal 3,2-enoyl-CoA isomerase, Peroxisomal Bifunctional Enzyme enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase 205222_at Cytoplasm enzyme 1962 74147 171142 EIF3D 66/67kDa, AA407891, EIF3-P66, eIF3-zeta, EIF3S7, MGC115774, MGC126526, MGC17258, MGC93918, MOE1 eukaryotic translation initiation factor 3, subunit D 200005_at Cytoplasm translation regulator 8664 55944 362952 EPRS 2410081F06Rik, 3010002K18Rik, BIFUNCTIONAL TRNA SYNTHETASE, C79379, DKFZp313B047, EARS, PARS, PIG32, Prs, QARS, QPRS glutamyl-prolyl-tRNA synthetase 200843_s_at Cytoplasm enzyme 2058 107508 289352 FDFT1 DGPT, ERG9, FARNESYL DIPHOSPHATE FARNESYL TRANSFERASE, Farnesyl diphosphate farnesyl transferase 1, Fpp farnesyl transferase 1, MGC93486, SQS, SQUALENE SYNTHASE, Squalene Synthetase, SS farnesyl-diphosphate farnesyltransferase 1 238666_at Cytoplasm enzyme TAK-475, zoledronic acid 2222 14137 29580 FHL1 bA535K18.1, FHL1B, KYO-T, KYOT1, KYOT2, LHL FOUR AND A HALF LIM DOMAINS 1, MGC111107, SLIM1 four and a half LIM domains 1 210299_s_at Cytoplasm other 2273 14199 25177 FLNA (includes EG:2316) ABP-280, ABP1, ABPX, DILP2, DKFZp434P031, F730004A14Rik, FILAMIN A, FILAMIN-1, FILAMIN-28, FLN, FLN1, Flna, Flna_predicted, FMD, MNS, NHBP, OPD, OPD1, OPD2, RGD1560614 filamin A, alpha (actin binding protein 280) 200859_x_at Cytoplasm other 2316 192176 293860 GART Adenosine3, AIRS, FTRG, Gaps, GARS, GARTF, MGC47764, PAIS, PGFT, PRGS phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 217445_s_at Cytoplasm enzyme LY231514 2618 14450 288259 HMGCR 3-hydroxy-3-methylglutaryl CoA reductase, 3H3M, HMG COA REDUCTASE, HMG-COAR, HMGR, HYDROXYMETHYLGLUTARYL-COENZYME A REDUCTASE, MGC103269, Red 3-hydroxy-3-methylglutaryl-Coenzyme A reductase 202539_s_at Cytoplasm enzyme aspirin/pravastatin, lovastatin/niacin, ezetimibe/simvastatin, amlodipine/atorvastatin, fluvastatin, cerivastatin, atorvastatin, pravastatin, simvastatin, lovastatin, rosuvastatin 3156 15357 25675 IDH1 AI314845, AI788952, E030024J03Rik, Id-1, IDH, IDP, IDPc, ISOCITRATE DEHYDROGENASE, MGC115782, PICD isocitrate dehydrogenase 1 (NADP+), soluble 242001_at Cytoplasm enzyme 3417 15926 24479 IMPA2 2210415D20Rik, AI326924, AW259601, MGC93085, Myo-inositol monophosphatase A2 inositol(myo)-1(or 4)-monophosphatase 2 203126_at Cytoplasm phosphatase 3613 114663 282636 IMPACT E430016J11RIK, MGC33718 Impact homolog (mouse) 222698_s_at Unknown other 55364 16210 497198 JTV1 AA407136, AA407225, AIMP2, MGC125271, MGC30261, MGC36346, MGC36522, MGC37389, P38, p38 tRNA synthetase complex component, PRO0992 JTV1 gene 202138_x_at Plasma Membrane other 7965 231872 288480 LDLR FH, FHC, Hlb301, LDL RECEPTOR, LDLRA low density lipoprotein receptor (familial hypercholesterolemia) 217173_s_at Plasma Membrane transporter 3949 16835 300438 LIMA1 1110021C24Rik, 3526402A12Rik, D15Ertd366e, EPLIN, FLJ38853, MGC131726, SREBP3 LIM domain and actin binding 1 222457_s_at Cytoplasm other 51474 65970 300228 MINA 1810047J07Rik, 2410057H13Rik, 3830408E23Rik, AI449204, DKFZp762O1912, FLJ14393, MDIG, MGC105305, MINA53, NO52 MYC induced nuclear antigen 213188_s_at Nucleus other 84864 67014 266670 MRPL12 0610034O11Rik, 1500031N16Rik, 5c5-2, L12mt, MGC8610, MRP-L31/34, MRPL7, MRPL7/L12, ribosomal protein, mitochondrial, L7, Rpl12, Rpm12, RPML12 mitochondrial ribosomal protein L12 203931_s_at Cytoplasm other 6182 56282 303746 MYC AU016757, C-MYC, C-MYC-P64, MGC105490, MGC138120, mMyc, Myc2, Niard, Nird, RNCMYC v-myc myelocytomatosis viral oncogene homolog (avian) 202431_s_at Nucleus transcription regulator 4609 17869 24577 MYCBP 5730488M09Rik, AMY-1, AW552132, AW742590, Mycbp_predicted c-myc binding protein 203359_s_at Nucleus transcription regulator 26292 56309 298513 NARS2 AI875199, FLJ23441, MGC125113, MGC41336, RGD1305145, SLM5 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 219217_at Unknown other 79731 244141 293128 PAICS 2610511I09Rik, ADE2, ADE2H1, AIRC, DKFZp781N1372, MGC1343, MGC5024, MGC93240, PAIS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 201013_s_at Unknown enzyme 10606 67054 140946 PCK2 1810010O14Rik, 9130022B02RIK, Pck2_predicted, PEPCK, PEPCK-M, PEPCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 202847_at Cytoplasm kinase 5106 74551 361042 Pdgf Pdgf Receptor Ligand, Platelet-Derived Growth Factor Unknown complex PDGF BB Pdgfb dimer Unknown complex PDGFD 1110003I09Rik, IEGF, MGC26867, MSTP036, rSCDGF-B, SCDGF-B platelet derived growth factor D 219304_s_at Extracellular Space growth factor 80310 71785 66018 PHB (includes EG:5245) BAP32, LOC688815, Phb, PROHIBITIN prohibitin 200659_s_at Nucleus transcription regulator 5245 18673 688815 PHB2 AU044498, BAP, BAP37, Bcap27, BCAP37, BCR ASSOCIATED PROTEIN37, MGC117268, p22, PNAS-141, REA, TERP1 prohibitin 2 201600_at Cytoplasm transcription regulator 11331 12034 114766 PIN4 2410002I22Rik, EG628161, EPVH, MGC138486, PAR14, PAR17, Parvulin 14, PPIase Pin4, Rotamase Pin4 protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin) 214224_s_at Nucleus enzyme 5303 628161, 69713 PMVK 1110011E12RIK, 2900002L22Rik, AV001327, HUMPMKI, MGC105660, Phosphomevalonate kinase, PMK, PMKA, PMKASE, PMKI phosphomevalonate kinase 203515_s_at Cytoplasm kinase 10654 68603 310645 QARS 1110018N24Rik, 1200016L19Rik, C80286, GLNRS, GLUTAMINYL TRANSSYNTHASE, Glutaminyl-tRNA synthetase, MGC105238, MGC94241, PRO2195, QRS glutaminyl-tRNA synthetase 217846_at Cytoplasm enzyme 5859 97541 290868 RPL13A 1810026N22Rik, 23-KD HIGHLY BASIC PROTEIN, MGC107571, Ribol13a, Ribosomal protein l13a, Tstap198-7, tum-antigen ribosomal protein L13a 200715_x_at Cytoplasm other 23521 22121 317646 RUVBL2 CGI-46, ECP51, MGC144733, MGC144734, mp47, P47, RuvB like DNA helicase, RVB2, TIP48, TIP49B, UPAR MRNABP RuvB-like 2 (E. coli) 201459_at Nucleus transcription regulator 10856 20174 292907 SCAMP1 4930505M11Rik, AI415563, AW122395, SCAMP, SCAMP37 secretory carrier membrane protein 1 212416_at Cytoplasm transporter 9522 107767 29521 SCAMP5 AI426171, AW558254, DKFZp686L1799, MGC24969, Sc5 secretory carrier membrane protein 5 212699_at Cytoplasm other 192683 56807 65171 SERBP1 1200009K13RIK, 9330147J08Rik, AL022786, CGI-55, CHD3IP, DKFZp564M2423, FLJ90489, HABP4L, MGC94773, PAI-RBP1, PAI1 MRNA BINDING PROTEIN, Rda288 SERPINE1 mRNA binding protein 1 227369_at Nucleus other 26135 66870 246303 SERINC3 AA959945, AA960047, AIGP1, DIFF33, MGC94574, SBBI99, TDE, TDE1, TMS-1 serine incorporator 3 221472_at Cytoplasm transporter 10955 26943 296350 SHMT1 AI324848, AI385541, C81125, CSHMT, Hydroxymethyltransferase, LRRGT00032, MGC15229, MGC24556, mSHMT, mshmt1, mshmt2, Serine Hydroxymethyl Transferase, SHMT serine hydroxymethyltransferase 1 (soluble) 209980_s_at Cytoplasm enzyme 6470 20425 287379 SLC1A1 D130048G10RIK, EAAC1, EAAC2, EAAT3, EXCITATORY AMINO ACID TRANSPORTER 3, GLUTAMATE TRANSPORTER, Glutamate transporter 1, MEAAC1, REAAC1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 213664_at Plasma Membrane transporter riluzole 6505 20510 25550 SLC29A1 1200014D21Rik, AA407560, ENT1, Es Nt, MGC1465, MGC3778, rENT1, Solute carrier family 29, member 1 solute carrier family 29 (nucleoside transporters), member 1 201801_s_at Plasma Membrane transporter 2030 63959 63997 SMARCA2 2610209L14RIK, BAF190, brahma, BRM, FLJ36757, HBRM, hSNF2a, MGC74511, SNF2, SNF2alpha, SNF2L2, SNF2LA, Sth1p, SWI2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 217707_x_at Nucleus transcription regulator 6595 67155 361745 SNRPN 2410045I01Rik, FE 294, FE 294 psi, HCERN3, MGC105406, MGC18604, MGC30325, Peg4, RT-LI, SM-D, SMN, SNRNP-N, SNURF-SNRPN small nuclear ribonucleoprotein polypeptide N 228370_at Nucleus other 6638 20646 81781 SNX17 5830447M19Rik, AI790646, D5Ertd260e, KIAA0064, mKIAA0064, XIG5 sorting nexin 17 200991_s_at Cytoplasm transporter 9784 266781 298836 SORBS3 MGC94509, SCAM-1, SH3D4, SH3P3, VINEXIN, VINEXIN ALPHA, VINEXIN BETA, vinexin-g sorbin and SH3 domain containing 3 207788_s_at Cytoplasm other 10174 20410 282843 SQLE AI323792, SQUALENE EPOXIDASE squalene epoxidase 209218_at Cytoplasm enzyme 6713 20775 29230 SREBF1 ADD-1, D630008H06, S14, SREBP-1, SREBP-1A, SREBP-1c, STEROL RESPONSE ELEMENT sterol regulatory element binding transcription factor 1 202308_at Nucleus transcription regulator 6720 20787 78968 TEAD4 EFTR-2, ETFR-2, FR-19, hRTEF-1B, MGC9014, RTEF-1, TCF13L1, Tcf13r1, TEF-3, TEFR-1, TEFR1A TEA domain family member 4 41037_at Nucleus transcription regulator 7004 21679 Tk 2'-deoxythymidine kinase, ATP:thymidine 5'-phosphotransferase, deoxythymidine kinase (phosphorylating), Thymidine kinase, thymidine kinase (phosphorylating) Unknown group TM7SF2 3110041O18Rik, ANG1, Av156900, DHCR14A, MGC108990 transmembrane 7 superfamily member 2 210130_s_at Cytoplasm enzyme 7108 73166 293688 TMEM97 1810014L12Rik, AI115531, Ai852985, AL022956, D11Bhm182e, MAC30, MGC102369, MGC105541, RGD1307423, RP23-399H5.9 transmembrane protein 97 214283_at Extracellular Space other 27346 69071 303330 TOR2A FLJ14771, MGC93778, MGC99558, SALUSIN, TORP1 torsin family 2, member A 227972_at Extracellular Space other 27433 30933 362112 TPP2 FLJ40359, TPP II tripeptidyl peptidase II 203375_s_at Cytoplasm peptidase 7174 22019 81815 WDR12 4933402C23Rik, FLJ10881, FLJ12719, FLJ12720, YTM1, Ytm1p WD repeat domain 12 218512_at Cytoplasm other 55759 57750 363237