Supplementary material for Eisen et al. (1998) Proc. Natl. Acad. Sci. USA 95(25), 14863-14868.

Yeast experiments clustered in Fig. 2.

 

Experiment ID

Experiment description

Reference sample

Time, min

Ref.

alpha 0

Cell-cycle: Alpha factor arrest and release

Unsynchronized culture

0

1

alpha 7

Cell-cycle: Alpha factor arrest and release

Unsynchronized culture

7

1

alpha 14

Cell-cycle: Alpha factor arrest and release

Unsynchronized culture

14

1

alpha 21

Cell-cycle: Alpha factor arrest and release

Unsynchronized culture

21

1

alpha 28

Cell-cycle: Alpha factor arrest and release

Unsynchronized culture

28

1

alpha 35

Cell-cycle: Alpha factor arrest and release

Unsynchronized culture

35

1

alpha 42

Cell-cycle: Alpha factor arrest and release

Unsynchronized culture

42

1

alpha 49

Cell-cycle: Alpha factor arrest and release

Unsynchronized culture

49

1

alpha 56

Cell-cycle: Alpha factor arrest and release

Unsynchronized culture

56

1

alpha 63

Cell-cycle: Alpha factor arrest and release

Unsynchronized culture

63

1

alpha 70

Cell-cycle: Alpha factor arrest and release

Unsynchronized culture

70

1

alpha 77

Cell-cycle: Alpha factor arrest and release

Unsynchronized culture

77

1

alpha 84

Cell-cycle: Alpha factor arrest and release

Unsynchronized culture

84

1

alpha 91

Cell-cycle: Alpha factor arrest and release

Unsynchronized culture

91

1

alpha 98

Cell-cycle: Alpha factor arrest and release

Unsynchronized culture

98

1

alpha 105

Cell-cycle: Alpha factor arrest and release

Unsynchronized culture

105

1

alpha 112

Cell-cycle: Alpha factor arrest and release

Unsynchronized culture

112

1

alpha 119

Cell-cycle: Alpha factor arrest and release

Unsynchronized culture

119

1

Elu 0

Cell-cycle: Elutriation

Unsynchronized culture

0

1

Elu 30

Cell-cycle: Elutriation

Unsynchronized culture

30

1

Elu 60

Cell-cycle: Elutriation

Unsynchronized culture

60

1

Elu 90

Cell-cycle: Elutriation

Unsynchronized culture

90

1

Elu 120

Cell-cycle: Elutriation

Unsynchronized culture

120

1

Elu 150

Cell-cycle: Elutriation

Unsynchronized culture

150

1

Elu 180

Cell-cycle: Elutriation

Unsynchronized culture

180

1

Elu 210

Cell-cycle: Elutriation

Unsynchronized culture

210

1

Elu 240

Cell-cycle: Elutriation

Unsynchronized culture

240

1

Elu 270

Cell-cycle: Elutriation

Unsynchronized culture

270

1

Elu 300

Cell-cycle: Elutriation

Unsynchronized culture

300

1

Elu 330

Cell-cycle: Elutriation

Unsynchronized culture

330

1

Elu 360

Cell-cycle: Elutriation

Unsynchronized culture

360

1

Elu 390

Cell-cycle: Elutriation

Unsynchronized culture

390

1

cdc15 10

Cell-cycle: cdc15 arrest and release

Unsynchronized culture

10

1

cdc15 30

Cell-cycle: cdc15 arrest and release

Unsynchronized culture

30

1

cdc15 50

Cell-cycle: cdc15 arrest and release

Unsynchronized culture

50

1

cdc15 70

Cell-cycle: cdc15 arrest and release

Unsynchronized culture

70

1

cdc15 90

Cell-cycle: cdc15 arrest and release

Unsynchronized culture

90

1

cdc15 110

Cell-cycle: cdc15 arrest and release

Unsynchronized culture

110

1

cdc15 130

Cell-cycle: cdc15 arrest and release

Unsynchronized culture

130

1

cdc15 150

Cell-cycle: cdc15 arrest and release

Unsynchronized culture

150

1

cdc15 170

Cell-cycle: cdc15 arrest and release

Unsynchronized culture

170

1

cdc15 190

Cell-cycle: cdc15 arrest and release

Unsynchronized culture

190

1

cdc15 210

Cell-cycle: cdc15 arrest and release

Unsynchronized culture

210

1

cdc15 230

Cell-cycle: cdc15 arrest and release

Unsynchronized culture

230

1

cdc15 250

Cell-cycle: cdc15 arrest and release

Unsynchronized culture

250

1

cdc15 270

Cell-cycle: cdc15 arrest and release

Unsynchronized culture

270

1

cdc15 290

Cell-cycle: cdc15 arrest and release

Unsynchronized culture

290

1

spo 0

Sporulation

Time 0

0

2

spo 2

Sporulation

Time 0

120

2

spo 5

Sporulation

Time 0

300

2

spo 7

Sporulation

Time 0

420

2

spo 9

Sporulation

Time 0

540

2

spo 11

Sporulation

Time 0

660

2

spo5 2

Sporulation

5-hr timepoint

120

2

spo5 7

Sporulation

5-hr timepoint

420

2

spo5 11

Sporulation

5-hr timepoint

660

2

spo- early

Sporulation in ndt80 knockout

2-hr timepoint

120

2

spo- mid

Sporulation in ndt80 knockout

5-hr timepoint

300

2

heat 0

Heat Shock 25-37C

Time 0

0

heat 10

Heat Shock 25-37C

Time 0

10

heat 20

Heat Shock 25-37C

Time 0

20

heat 40

Heat Shock 25-37C

Time 0

40

heat 80

Heat Shock 25-37C

Time 0

80

heat 160

Heat Shock 25-37C

Time 0

160

dtt 15

DTT Shock 1mm

Time 0

15

dtt 30

DTT Shock 1mm

Time 0

30

dtt 60

DTT Shock 1mm

Time 0

60

dtt 120

DTT Shock 1mm

Time 0

120

cold 0

Cold Shock 25-11

Time 0

0

cold 20

Cold Shock 25-12

Time 0

20

cold 40

Cold Shock 25-13

Time 0

40

cold 160

Cold Shock 25-14

Time 0

160

diau a

Diauxic Shift

Time 0

540

3

diau b

Diauxic Shift

Time 0

660

3

diau c

Diauxic Shift

Time 0

780

3

diau d

Diauxic Shift

Time 0

900

3

diau e

Diauxic Shift

Time 0

1020

3

diau f

Diauxic Shift

Time 0

1140

3

diau g

Diauxic Shift

Time 0

1260

3

1. Spellman, P. T., Sherlock, G., Iyer, V. R., Zhang, M., Anders, K., Eisen, M. B., Brown, P. O., Botstein, D. & Futcher, B. (1998) Mol. Biol. Cell, in press.

2. Chu, S., DeRisi, J., Eisen, M., Mulholland, J., Botstein, D., Brown, P. O. & Herskowitz, I. (1998) Science 282, 699-705.

3. DeRisi, J. L., Iyer, V. R. & Brown, P. O. (1997) Science 278, 680-686.