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Figure S1. Silnoon, a Drosophila homologue of mammalian MCT, genetically interacts with LKB1 and is broadly expressed in various tissues. (A) Microscopy images of adult eyes from the indicated genotypes. (B) Tissue-specific Northern blot analysis of Sln in wild-type adult flies. H, head; Th, thorax; Ab, abdomen; Ov, ovary; Te, testis. 28S rRNA was used as a loading control. (C) Alignment of the amino acid sequences of human MCT1 (hMCT1), mouse MCT1 (mMCT1), and Drosophila Sln. Pink boxes indicate predicted 12 transmembrane domains (TM1–12). A mutated residue in the SlnG366V allele is indicated by an asterisk.