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Figure S4. KcsA-based homology modeling of G657 and N658 native side chains. (A and B) KcsA-based homology modeling of adjacent residues G657 and N658. α-helices for S5 through S6 are represented as gray ribbons. Space-filled spheres represent the native G657 (blue) and N658 (red) side chains. (A) View of the closed-state MlotiK1 homology model shows G657 and N658 located next to each other in the heart of the vestibule. (B) View from the cytoplasm of G657 and N658.