Increased Interleukin (IL)-1β Messenger Ribonucleic Acid Expression in β-Cells of Individuals with Type 2 Diabetes and Regulation of IL-1β in Human Islets by Glucose and Autostimulation
J Clin Endocrinol Metab Böni-Schnetzler et al. 93: 4065 Supplemental Data
Supplemental Data
Files in this Data Supplement:
- Supplemental Table 1 - Clinical data of diabetic and control subjects
- Supplemental Figure 1 - Linear regression analysis of basal IL-1β mRNA versus glucose inhibited IL-1Ra. Human islets were cultured for 4 days at 5.5 (basal) or 33.3 mM glucose and IL-1Ra mRNA levels were quantified using 18s RNA as an internal standard.
- Supplemental Figure 2 - Linear regression of IL-1β autostimulation and glucose induced IL-1β mRNA (n=12). Human islets were cultured for 4 days at 5.5 (basal) or 33.3 mM glucose and IL-1Ra mRNA levels were quantified using 18s RNA as an internal standard.