This file contains a list of COGs in the following format:

CSN_COG#_one line description of COG members
Average identity between core members (genes that are members due to congruent BeTs)
   List of genes in COG core in this format:
   [Virus_#gene number] [the sequence's PID number] [Genbank annotation] [add. annotation (op.)]
  Average identity to the core members of the additional members
     List of genes that are Additional Members of the COG
     (due to non-congruent BeTs to Core members) Same format as core.

The COG# assigned each COG is arbitrary and not related to the number assigned any similar COGs at other CSNs. The "gene number" after the "#" was assigned for internal reference purposes.

COG Stringency Number for cores is 12
COG Stringency Number for addition is 12

Core Members : Average percent Identity : 24.3074545454545

   EHV1_#32 gi|330824 virion protein

   EHV2_#7 gi|695179 ORF 07

   EHV4_#32 gi|2605976 32

   HCMV_#70 gi|1780834 HCMVUL56

   HSV1_#31 gi|59528|gnl|PID|e312343 UL28 Req for DNA cleavage-packaging

   HSV2_#31 gi|1869851|gnl|PID|e304174 UL28

   VZV_#30 gi|60019 ORF30 (AA1-770)

   EBV_#86 gi|1334915|gnl|PID|e24996 BALF3 reading frame

   HHV6_#50 gi|854019 U40

   HHV7_#45 gi|1139642 U40 gene product

   MHV68_#7 gi|2317928 transport protein

   HVS2_#8 gi|60328 transport protein

  Additional Members : Average Identity to Core : 0

Core Members : Average percent Identity : 27.1420909090909

   EHV1_#31 gi|330823 single stranded DNA binding protein

   EHV2_#6 gi|695178 single-stranded DNA binding protein

   EHV4_#31 gi|2605975 31

   HCMV_#71 gi|1780835 Major DNA binding protein

   HSV1_#32 gi|59529|gnl|PID|e312344 UL29 ssDNA binding protein

   HSV2_#32 gi|1869852|gnl|PID|e304273 UL29

   VZV_#29 gi|60018 ORF29 (AA1-1204)

   EBV_#87 gi|1334916 BALF2 early ORF, homologous to RF 29 VZV and major DNA bind

   HHV6_#51 gi|854020 U41, major DNA binding protein

   HHV7_#46 gi|1139643 major DNA binding protein

   MHV68_#6 gi|2317927 ssDNA binding protein

   HVS2_#7 gi|60327 major ssDNA-binding protein

  Additional Members : Average Identity to Core : 0

Core Members : Average percent Identity : 20.6603257575758

   EHV1_#21 gi|330813 ribonucleotide reductase RR1

   EHV2_#62 gi|695234 ribonucleotide reductase, large subunit

   EHV4_#21 gi|2605964 21

   HCMV_#59 gi|1780823 Homology to large subunit of ribonucleotide reductase

   HSV1_#42 gi|59539|gnl|PID|e312354 ribonucleotide reductase large subunit

   HSV2_#42 gi|1869862|gnl|PID|e304181 ribonucleotide reductase large subunit

   VZV_#19 gi|60008 ORF19 (AA1-775)

   EBV_#23 gi|1334856 BORF2 early ORF, 2 NXT/S. Homology HSV 140K ribonucleotide

   HHV6_#38 gi|854007 U28, RR1

   HHV7_#33 gi|1139630 ribonucleotide reductase, large subunit

   MHV68_#59 gi|2317993 ribonucleotide reductase large

   HVS2_#62 gi|60382 ribonucleotide reductase,large subunit

  Additional Members : Average Identity to Core : 0

Core Members : Average percent Identity : 20.5429848484849

   EHV1_#7 gi|330799 associated with a DNA helicase/primase complex;

   EHV2_#57 gi|695229 DNA helicase-primase complex component

   EHV4_#7 gi|2606017 7

   HCMV_#84 gi|1780848|gnl|PID|e27270 Homology to HSV-1 prot required for DNA replication

   HSV1_#56 gi|59552|gnl|PID|e312368 UL52 . component of helicase/primase complex

   HSV2_#56 gi|1869876|gnl|PID|e304282 UL52

   VZV_#6 gi|59995 ORF6 (AA1-1083)

   EBV_#29 gi|1334862 BSLF1 reading frame, homologous to RF 6 VZV

   HHV6_#53 gi|854022 U43, helicase-primase complex

   HHV7_#48 gi|1139645 primase

   MHV68_#53 gi|2317955 DNA replication protein

   HVS2_#57 gi|60376 ORF 56; EDRF4; sim. to other HV

  Additional Members : Average Identity to Core : 0

Core Members : Average percent Identity : 19.3789545454546

   EHV1_#28 gi|330820 virion protein

   EHV2_#71 gi|695243 ORF 68

   EHV4_#28 gi|2605971 28

   HCMV_#66 gi|1780830 HCMVUL52

   HSV1_#35 gi|59533|gnl|PID|e312347 UL32 ts mutant is deficient in DNA packaging

   HSV2_#35 gi|1869855|gnl|PID|e304274 UL32

   VZV_#26 gi|60014 ORF26 (AA1-585)

   EBV_#16 gi|1334849 BFLF1 reading frame, 2 NXT/S homologous to RF 26 in VZV and HFRF1 in

   HHV6_#46 gi|854015 U36

   HHV7_#41 gi|1139638 putative virion protein

   MHV68_#66 gi|2317960 glycoprotein

   HVS2_#69 gi|60389 ORF 68; ECRF1; sim. to other HV

  Additional Members : Average Identity to Core : 0

Core Members : Average percent Identity : 27.5661212121212

   EHV1_#30 gi|330822 DNA polymerase

   EHV2_#9 gi|695181 DNA polymerase replicative subunit

   EHV4_#30 gi|2605974 30

   HCMV_#68 gi|1780832 DNA polymerase (8)

   HSV1_#33 gi|59530|gnl|PID|e312345 DNA polymerase

   HSV2_#33 gi|1869853|gnl|PID|e304175 DNA polymerase

   VZV_#28 gi|60017 ORF28 (AA1-1194)

   EBV_#84 gi|1334913 BALF5 DNA pol (early), homologous to many DNA polymerases, CMV

   HHV6_#48 gi|854017 U38, DNA polymerase

   HHV7_#43 gi|1139640 DNA polymerase

   MHV68_#9 gi|2317930 DNA polymerase

   HVS2_#10 gi|60330 DNA polymerase

  Additional Members : Average Identity to Core : 0

Core Members : Average percent Identity : 24.0343787878788

   EHV1_#37 gi|330829 virion protein

   EHV2_#19 gi|695191 tegument protein

   EHV4_#37 gi|2605981 36

   HCMV_#91 gi|1780854 HCMVUL77

   HSV1_#27 gi|59525|gnl|PID|e312339 capsid associated tegument protein

   HSV2_#27 gi|1869847|gnl|PID|e304271 capsid associated tegument protein

   VZV_#34 gi|60023 ORF34 (AA1-579)

   EBV_#79 gi|1334908 BVRF1 early reading frame, homologous to RF 34 VZV

   HHV6_#60 gi|854029 U50

   HHV7_#55 gi|1139652 viron protein

   MHV68_#17 gi|2317973 tegument protein

   HVS2_#20 gi|60340 ORF 19; sim. to other HV

  Additional Members : Average Identity to Core : 0

Core Members : Average percent Identity : 28.1842878787879

   EHV1_#57 gi|330848 associated with a DNA helicase/primase complex;

   EHV2_#45 gi|695217 DNA helicase-primase complex component

   EHV4_#57 gi|2606003 57

   HCMV_#120 gi|1780883 Homology to helicases

   HSV1_#7 gi|59507|gnl|PID|e312319 complexes with UL8 & UL52 proteins. UL5

   HSV2_#7 gi|1869827|gnl|PID|e304159 UL5

   VZV_#54 gi|60044 ORF 55 (AA1-881)

   EBV_#54 gi|1334885 BBLF4 early reading frame, very good homology to RF55 VZV

   HHV6_#87 gi|854056 old name HDRF2; helicase, part of helicase-primase complex

   HHV7_#81 gi|1139678 helicase

   MHV68_#41 gi|2317951 helicase-primase

   HVS2_#45 gi|60364 helicase

  Additional Members : Average Identity to Core : 0

Core Members : Average percent Identity : 28.7044242424243

   EHV1_#61 gi|330852 uracil-DNA glycosylase

   EHV2_#47 gi|695219 uracil DNA glycosylase

   EHV4_#61 gi|2606008 61

   HCMV_#131 gi|1780896 Homology to uracil-DNA glycosylase

   HSV1_#4 gi|59503|gnl|PID|e312316 uracil-DNA glycosylase (aka UL2)

   HSV2_#4 gi|1869824|gnl|PID|e304157 uracil-DNA glycosylase

   VZV_#58 gi|60048 ORF 59 (AA1-305)

   EBV_#52 gi|1632795|gnl|PID|e25020 BKRF3 reading frame, homologous to RF 59 VZV

   HHV6_#90 gi|854059 U81, uracil-DNA glycosylase

   HHV7_#86 gi|1139683 uracil-DNA glycosylase

   MHV68_#43 gi|2317983 uracil DNA glycosylase

   HVS2_#47 gi|60367 uracil DNA glucosidase

  Additional Members : Average Identity to Core : 0

Core Members : Average percent Identity : 23.9678409090909

   EHV1_#36 gi|330827 protease

   EHV2_#17 gi|695188 proteinase/capsid scaffold protein

   EHV4_#36 gi|2605979 35

   HCMV_#94 gi|1780857 HCMVUL80

   HSV1_#28 gi|59526|gnl|PID|e312340 protease

   HSV2_#28 gi|1869848|gnl|PID|e304172 protease

   VZV_#33 gi|60022 ORF33 (AA1-605)

   EBV_#80 gi|1334909 BVRF2 early reading frame, N-terminus homologous to RF 33 VZV

   HHV6_#63 gi|854032 U53, protease-assembly protein

   HHV7_#58 gi|1139655 protease

   MHV68_#15 gi|2317972 capsid protein

   HVS2_#18 gi|60339 ORF 17; similarity to other herpesviruses (HV)

  Additional Members : Average Identity to Core : 0

Core Members : Average percent Identity : 33.7684090909091

   EHV1_#43 gi|330835 major capsid protein

   EHV2_#25 gi|695197 capsid protein

   EHV4_#43 gi|2605988 42

   HCMV_#101 gi|1780864 Major capsid protein (12)

   HSV1_#21 gi|59519|gnl|PID|e312333 major capsid protein

   HSV2_#21 gi|1869841|gnl|PID|e304168 major capsid protein

   VZV_#40 gi|60029 ORF40 (AA1-1396)

   EBV_#73 gi|1334902 BcLF1 late ORF, homologous to RF 40 VZV and major capsid pr

   HHV6_#67 gi|854036 U57, major capsid protein

   HHV7_#63 gi|1139660 major capsid protein

   MHV68_#23 gi|2317938 major capsid protein

   HVS2_#26 gi|60346 major capsid protein

  Additional Members : Average Identity to Core : 0

Core Members : Average percent Identity : 26.0679696969697

   EHV1_#52 gi|330843 membrane protein

   EHV2_#40 gi|695212 glycoprotein M

   EHV4_#52 gi|2605998 52

   HCMV_#115 gi|1780879 Multiple hydrophobic domains

   HSV1_#12 gi|59510|gnl|PID|e312324 virion glycoprotein M

   HSV2_#12 gi|1869832|gnl|PID|e304162 virion glycoprotein M

   VZV_#49 gi|60040 ORF 50 (AA1-435)

   EBV_#59 gi|1334889 BBRF3 late reading frame

   HHV6_#82 gi|854051 U72, integral membrane protein, glycoprotein M, gM

   HHV7_#76 gi|1139673 glycoprotein M

   MHV68_#37 gi|2317979 glycoprotein M

   HVS2_#40 gi|60360 integral membrane protein

  Additional Members : Average Identity to Core : 0

Core Members : Average percent Identity : 18.363303030303

   EHV1_#50 gi|330841 deoxyribonuclease

   EHV2_#38 gi|695210 deoxyribonuclease

   EHV4_#50 gi|2605996 50

   HCMV_#113 gi|1780877 DNase homologue

   HSV1_#14 gi|59513|gnl|PID|e312326 deoxyribonuclease

   HSV2_#14 gi|1869834|gnl|PID|e304266 deoxyribonuclease

   VZV_#47 gi|60037 ORF 48 (AA1-551)

   EBV_#61 gi|1334891 BGLF5 early ORF, homologous to RF 48 VZV and alkaline exonu

   HHV6_#80 gi|854049 U70, alkaline exonuclease

   HHV7_#74 gi|1139671 alkaline exonuclease

   MHV68_#35 gi|2317948 alkaline exonuclease

   HVS2_#38 gi|60358 alkaline exonuclease

  Additional Members : Average Identity to Core : 0

Core Members : Average percent Identity : 21.4712954545455

   EHV1_#56 gi|330847 virion protein

   EHV2_#44 gi|695216 minor capsid protein

   EHV4_#56 gi|2606002 56

   HCMV_#119 gi|1780884 HCMVUL104

   HSV1_#8 gi|59506|gnl|PID|e312320 minor capsid protein

   HSV2_#8 gi|1869828|gnl|PID|e304264 minor capsid protein

   VZV_#53 gi|60043 ORF 54 (AA1-769)

   EBV_#55 gi|1334884 BBRF1 late reading frame, homologous to RF 54 VZV

   HHV6_#86 gi|854055 U76

   HHV7_#80 gi|1139677 putative viron protein

   MHV68_#40 gi|2317981 capsid protein

   HVS2_#44 gi|60365 ORF 43; sim. to other HV

  Additional Members : Average Identity to Core : 0