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Particles influence on cell membrane integrity. (A) The disrupted cell membrane of TiO2 exposed LLC cells were stained with FM1-43 membrane stain (red). (B) TiO2 particles can be visualized surrounding cells under phase contrast optical microscope. (C) By overlapping membrane stain images and optical image, membranes can be seen to coincide with the particles indicating potential involvement of particles on cell membrane disintegration.
