Supplementary table 1: SPM results for the entire scan volume (both contexts collapsed)
z-value | p-value | p-value | x | y | z | localization |
| (uncorr.) | (SVC) | (MNI | space) |
|
|
| ||||||
PLACEBO | ||||||
(CS+>CS-)across contexts | ||||||
3.46 | <0.001 |
| -20 | -50 | -40 | L cerebellum |
| ||||||
(CS+>CS-), SCR-modulated, across contexts | ||||||
no voxels surviving threshold | ||||||
| ||||||
DCS | ||||||
(CS+>CS-)across contexts | ||||||
no voxels surviving threshold | ||||||
| ||||||
(CS+>CS-), SCR-modulated, across contexts | ||||||
4.16 | <0.001 |
| -40 | 12 | -44 | L temporal pole |
3.81 | <0.001 |
| 18 | 58 | 24 | anterior R superior frontal gyrus/sulcus |
3.79 | <0.001 |
| 12 | 36 | 36 | R ACC/ dorsal MPFC |
3.38 | <0.001 |
| -36 | 30 | -22 | L OFC (posterior or lateral orbital gyrus) |
3.18 | 0.001 |
| 10 | 58 | 46 | R superior frontal gyrus |
| ||||||
PLACEBO vs. DCS | ||||||||||||
(CS+>CS-)placebo > (CS+>CS-)DCS, across contexts | ||||||||||||
3.73 | <0.001 |
| -22 | -48 | -42 | L cerebellum | ||||||
| ||||||||||||
(CS+>CS-)placebo > (CS+>CS-)DCS, SCR-modulated, across contexts | ||||||||||||
no voxels surviving threshold | ||||||||||||
| ||||||||||||
(CS+>CS-)DCS > (CS+>CS-)placebo, across contexts | ||||||||||||
no voxels surviving threshold | ||||||||||||
| ||||||||||||
(CS+>CS-)DCS > (CS+>CS-)placebo, SCR-modulated, across contexts | ||||||||||||
4.58 | <0.001 |
| 16 | 58 | 26 | anterior R frontal sulcus extending into | ||||||
4.20 | <0.001 | 0.009(1) | 8 | 48 | 40 | dorsal R MPFC and | ||||||
3.83 | <0.001 |
| 36 | 60 | 0 | R inferior frontal gyrus | ||||||
4.22 | <0.001 |
| -18 | 62 | 4 | L frontal pole | ||||||
3.85 | <0.001 |
| 68 | -30 | -10 | R middle temporal gyrus | ||||||
3.75 | <0.001 |
| 68 | -26 | -28 |
| ||||||
3.72 | <0.001 |
| -34 | 30 | -16 | L OFC (posterior or lateral orbital gyrus) | ||||||
3.67 | <0.001 |
| -16 | 62 | 24 | anterior L frontal sulcus extending into | ||||||
3.49 | <0.001 |
| -4 | 56 | -8 | L ventral MPFC | ||||||
3.41 | <0.001 |
| 2 | 58 | 0 | R ventral MPFC | ||||||
3.66 | <0.001 |
| 68 | -8 | -24 | R middle temporal gyrus | ||||||
3.60 | <0.001 |
| 12 | 26 | -12 | R OFC (olfactory sulcus) | ||||||
3.49 | <0.001 |
| 10 | 24 | -20 |
| ||||||
3.59 | <0.001 |
| 6 | 36 | -32 | R OFC (gyrus rectus) | ||||||
3.41 | <0.001 |
| -24 | -108 | -8 | L occipital cortex | ||||||
3.38 | <0.001 |
| 18 | -50 | 10 | R anterior calcarine sulcus | ||||||
3.31 | <0.001 |
| -72 | -42 | -10 | L middle temporal gyrus | ||||||
3.25 | 0.001 |
| 8 | 50 | 6 | R rostral ACC | ||||||
3.19 | 0.001 |
| -56 | -18 | 22 | L insula | ||||||
3.14 | 0.001 |
| -6 | -60 | 4 | L anterior calcarine sulcus | ||||||
Threshold ≤ 0.01 (selected): | ||||||||||||
3.12 | 0.001 | 0.022(2) | -34 | -30 | -18 | L hippocampus/collateral sulcus | ||||||
T-tests, degrees of freedom: 12 (placebo), 9 (DCS), 22 (placebo vs. DCS), statistical threshold P £ 0.001 uncorrected, one-tailed, unless indicated otherwise. Clusters <5 voxels not reported. ACC: anterior cingulate cortex, OFC: orbital frontal cortex, MNI: Montreal Neurological Institute, MPFC: medial prefrontal cortex, SCR: skin conductance response, SVC: small volume correction.
(1)SVC yields three separate maxima (see main text); (2)SVC shifts maximum to -34/-32/-16