Supplementary table 2: SPM results for the entire scan volume (context A only)

 

z-value

p-value

p-value

x

y

z

localization

 

(uncorr.)

(SVC)

(MNI 

space)

 

 

 

PLACEBO

(CS+>CS-)across contexts, context A

3.89

3.41

3.18

<0.001

<0.001

0.001

 

30

30

28

-66

-46

-56

-12

-14

0

R fusiform gyrus

 

3.56

3.32

<0.001

<0.001

 

-50

-48

-2

4

34

28

L inferior frontal gyrus

 

(CS+>CS-), SCR-modulated, context A

no voxels surviving threshold

 

DCS

(CS+>CS-)across contexts, context A

no voxels surviving threshold

 

(CS+>CS-), SCR-modulated, context A

4.21

<0.001

 

-38

38

-24

L lateral OFC

3.22

0.001

 

10

34

24

R dorsal ACC

3.20

0.001

 

62

22

8

R inferior frontal gyrus

 

PLACEBO vs. DCS

(CS+>CS-)placebo > (CS+>CS-)DCS, context A

4.43

<0.001

 

30

-66

-12

R fusiform gyrus

4.22

<0.001

 

-38

-46

-14

R fusiform gyrus

3.26

0.001

 

-24

-94

-44

L cerebellum

 

 (CS+>CS-)placebo > (CS+>CS-)DCS, SCR-modulated, context A

no voxels surviving threshold

 

(CS+>CS-)DCS > (CS+>CS-)placebo, context A

no voxels surviving threshold

 

(CS+>CS-)DCS > (CS+>CS-)placebo, SCR-modulated, context A

3.77

<0.001

 

-58

14

10

L inferior frontal gyrus

3.68

<0.001

 

-44

16

6

L anterior insula

3.60

<0.001

0.032(1)

-6

38

22

L rostral ACC

3.40

<0.001

 

74

-32

6

R superior temporal gyrus

3.39

<0.001

 

74

-38

-2

 

3.38

<0.001

 

74

-30

-16

R middle temporal gyrus

3.34

<0.001

 

-34

30

-16

L lateral OFC

3.30

<0.001

 

-10

20

32

L dorsal ACC

3.25

0.001

 

-56

-18

18

L frontal operculum

   extending into

3.21

0.001

 

-62

-16

12

   L temporal operculum

3.15

0.001

 

-50

-22

6

   L temporal operculum

3.23

0.001

 

50

-22

2

R temporal operculum or   

   superior temporal sulcus

 

 

T-tests, degrees of freedom: 12 (placebo), 9 (DCS), 22 (placebo vs. DCS), statistical threshold P £ 0.001 uncorrected, one-tailed, unless indicated otherwise. Clusters <5 voxels not reported. ACC: anterior cingulate cortex, OFC: orbital frontal cortex, MNI: Montreal Neurological Institute, MPFC: medial prefrontal cortex, SCR: skin conductance response, SVC: small volume correction.

(1)SVC shifts maximum to -4/42/24