GENE Name DESC Status Pos Coords %Uniqueness YPD0.1 (rpkb) YPD0.2 (rpkb) YPD15.1 (rpkb) YPD15.2 (rpkb) HS15.1 (rpkb) HS15.2 (rpkb) YPD0 (rpkb) YPD15 (rpkb) HS15 (rpkb) YPD0 (copies/cell) YPD15 (copies/cell) HS15 (copies/cell) log2(HS15/YPD15)[Seq] log2(HS15/YPD15)[Hyb] CorrSTU
YAL069W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr1:335-649 335-649 35.8% 8.86 0.00 8.86 0.00 0.00 8.86 4.43 4.43 4.43 0.02 0.02 0.02 0.00 -0.17
YAL068W-A "Dubious open reading frame unlikely to encode a protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr1:538-792 538-792 23.3% 0.00 0.00 0.00 0.00 0.00 16.83 0.00 0.00 8.42 0.00 0.00 0.03 Inf NaN
YAL068C Hypothetical protein Uncharacterized chr1:1807-2169 1807-2169 3.7% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.44
YAL067W-A "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr1:2480-2707 2480-2707 16.7% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN NaN
YAL067C SEO1 "Putative permease, member of the allantoate transporter subfamily of the major facilitator superfamily; mutation confers resistance to ethionine sulfoxide" Verified chr1:7236-9017 7236-9017 99.1% 4.53 3.96 3.40 3.40 6.79 9.62 4.24 3.40 8.21 0.02 0.01 0.03 1.27 -0.36
YAL066W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr1:10092-10400 10092-10400 99.6% 3.25 0.00 0.00 0.00 0.00 0.00 1.62 0.00 0.00 0.01 0.00 0.00 NaN NaN
YAL065C Putative protein of unknown function; has homology to FLO1; possible pseudogene Uncharacterized chr1:11566-11952 11566-11952 39.1% 6.61 13.22 13.22 0.00 19.83 33.05 9.91 6.61 26.44 0.04 0.03 0.11 2.00 -0.02
YAL064W-B Fungal-specific protein of unknown function Uncharacterized chr1:12047-12427 12047-12427 11.5% 0.00 22.84 0.00 22.84 22.84 22.84 11.42 11.42 22.84 0.04 0.05 0.09 1.00 0.73
YAL064C-A Putative protein of unknown function; YAL064C-A is not an essential gene Uncharacterized chr1:13364-13744 13364-13744 73.6% 32.09 21.39 39.22 17.83 32.09 78.43 26.74 28.52 55.26 0.10 0.12 0.23 0.95 0.68
YAL064W "Protein of unknown function; may interact with ribosomes, based on co-purification experiments" Verified chr1:21526-21852 21526-21852 39.6% 0.00 0.00 0.00 0.00 7.73 7.73 0.00 0.00 7.73 0.00 0.00 0.03 Inf 0.81
YAL063C-A Putative protein of unknown function; identified by expression profiling and mass spectrometry Uncharacterized chr1:22397-22687 22397-22687 46.0% 7.47 7.47 7.47 0.00 7.47 7.47 7.47 3.73 7.47 0.03 0.02 0.03 1.00 NaN
YAL063C FLO9 "Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation" Verified chr1:24001-27969 24001-27969 17.9% 45.12 36.66 28.20 15.51 31.02 16.92 40.89 21.85 23.97 0.15 0.09 0.10 0.13 0.49 Frag<80[2]
YAL062W GDH3 "NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources" Verified chr1:31568-32941 31568-32941 97.3% 65.81 86.01 67.31 52.35 195.95 133.13 75.91 59.83 164.54 0.28 0.24 0.68 1.46 0.73 Matched[4]
YAL061W BDH2 Putative medium-chain alcohol dehydrogenase with similarity to BDH1; transcription induced by constitutively active PDR1 and PDR3; BDH2 is an essential gene Uncharacterized chr1:33449-34702 33449-34702 98.1% 121.12 160.95 286.94 240.61 2773.51 2137.85 141.03 263.78 2455.68 0.52 1.07 10.17 3.22 3.01 Matched[5]
YAL060W BDH1 "NAD-dependent (2R,3R)-2,3-butanediol dehydrogenase, a zinc-containing medium-chain alcohol dehydrogenase, produces 2,3-butanediol from acetoin during fermentation and allows using 2,3-butanediol as a carbon source during aerobic growth" Verified chr1:35156-36304 35156-36304 98.5% 646.62 907.21 726.12 741.14 2734.88 1817.07 776.91 733.63 2275.98 2.87 2.98 9.43 1.63 1.42 Matched[6]
YAL059W ECM1 "Protein of unknown function, localized in the nucleoplasm and the nucleolus, genetically interacts with MTR2 in 60S ribosomal protein subunit export" Verified chr1:36510-37148 36510-37148 98.2% 277.18 117.88 152.93 111.51 41.42 27.08 197.53 132.22 34.25 0.73 0.54 0.14 -1.95 -2.74 Covered/w/another[7]
YAL059C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene ECM1/YAL059W" Dubious chr1:36497-36919 36497-36919 98.3% 218.86 96.20 115.44 108.23 38.48 16.84 157.53 111.83 27.66 0.58 0.45 0.11 -2.02 NaN Covered/w/another[7]
YAL058W CNE1 "Calnexin; integral membrane ER chaperone involved in folding and quality control of glycoproteins; chaperone activity is inhibited by Mpd1p, with which Cne1p interacts; 24% identical to mammalian calnexin; Ca+ binding not yet shown in yeast" Verified chr1:37465-38973 37465-38973 98.6% 112.92 89.39 98.13 88.72 85.36 106.20 101.16 93.43 95.78 0.37 0.38 0.40 0.04 0.75 Covered/w/another[7]
YAL056C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr1:38697-39047 38697-39047 98.9% 126.74 112.34 109.46 74.89 100.82 112.34 119.54 92.17 106.58 0.44 0.37 0.44 0.21 0.15 Covered/w/another[7]
YAL056W GPB2 "Proposed beta subunit of the heterotrimeric G protein; interacts with the receptor Grp1p, affects signaling by altering the level of phosphorylation of PKS substrates; regulates pseudohyphal growth through cAMP levels; homolog of Gpb1p" Verified chr1:39260-41902 39260-41902 98.6% 128.90 161.12 123.91 115.47 121.61 102.43 145.01 119.69 112.02 0.54 0.49 0.46 -0.10 0.01 Covered/w/another[8]
YAL055W PEX22 "Putative peroxisomal membrane protein required for import of peroxisomal proteins, functionally complements a Pichia pastoris pex22 mutation" Verified chr1:42178-42720 42178-42720 98.1% 108.85 144.51 120.11 106.98 236.47 116.36 126.68 113.54 176.42 0.47 0.46 0.73 0.64 0.49 Covered/w/another[8]
YAL054C ACS1 "Acetyl-coA synthetase isoform which, along with Acs2p, is the nuclear source of acetyl-coA for histone acetlyation; expressed during growth on nonfermentable carbon sources and under aerobic conditions" Verified chr1:42882-45023 42882-45023 98.6% 31.73 40.73 42.15 30.31 88.09 54.94 36.23 36.23 71.52 0.13 0.15 0.30 0.98 0.49 Frag<80[9]
YAL053W FLC2 Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance Verified chr1:45900-48251 45900-48251 99.0% 162.39 153.36 150.36 119.43 142.19 130.60 157.87 134.89 136.40 0.58 0.55 0.57 0.02 0.58 Matched[10]
YAL051W OAF1 "Oleate-activated transcription factor, acts alone and as a heterodimer with Pip2p; activates genes involved in beta-oxidation of fatty acids and peroxisome organization and biogenesis" Verified chr1:48565-51708 48565-51708 98.9% 73.00 62.38 56.92 56.27 68.49 70.10 67.69 56.60 69.30 0.25 0.23 0.29 0.29 0.71 Matched[11]
YAL049C "Cytoplasmic protein of unknown function, potential Hsp82p interactor" Uncharacterized chr1:51856-52596 51856-52596 99.0% 340.81 298.55 373.53 298.55 554.84 399.43 319.68 336.04 477.14 1.18 1.36 1.98 0.51 0.60 Matched[12]
YAL047W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr1:54585-54914 54585-54914 99.1% 21.40 24.45 15.28 9.17 30.57 36.68 22.92 12.23 33.62 0.08 0.05 0.14 1.46 NaN Covered/w/another[13]
YAL048C GEM1 "Evolutionarily-conserved tail-anchored outer mitochondrial membrane GTPase which regulates mitochondrial morphology; cells lacking Gem1p contain collapsed, globular, or grape-like mitochondria; not required for pheromone-induced cell death" Verified chr1:52802-54790 52802-54790 99.0% 42.14 48.23 42.14 44.68 37.06 45.69 45.18 43.41 41.38 0.17 0.18 0.17 -0.07 0.82 Matched[13]
YAL047C SPC72 "Component of the cytoplasmic Tub4p (gamma-tubulin) complex, binds spindle pole bodies and links them to microtubules; has roles in astral microtubule formation and stabilization" Verified chr1:54990-56858 54990-56858 99.2% 51.76 56.62 49.07 50.69 57.69 46.91 54.19 49.88 52.30 0.20 0.20 0.22 0.07 0.57 Matched[14]
YAL046C Putative protein of unknown function; YAL046C is not an essential gene Uncharacterized chr1:57030-57386 57030-57386 98.9% 212.39 192.57 252.04 184.07 305.84 164.25 202.48 218.05 235.04 0.75 0.89 0.97 0.11 -0.12 Matched[15]
YAL044W-A Putative protein of unknown function; similar to S. pombe uvi31 which is a putative DNA repair protein Uncharacterized chr1:57519-57851 57519-57851 98.5% 310.94 350.57 344.47 301.79 506.03 289.60 330.75 323.13 397.82 1.22 1.31 1.65 0.30 -0.10 Matched[16]
YAL045C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; almost completely overlaps YAL044W-A" Dubious chr1:57489-57797 57489-57797 98.5% 285.83 344.97 315.40 282.55 440.25 236.55 315.40 298.97 338.40 1.16 1.21 1.40 0.18 -0.48 Matched[16]
YAL044C GCV3 "H subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of levels of 5,10-methylene-THF in the cytoplasm" Verified chr1:57951-58463 57951-58463 98.6% 2555.34 2387.35 2561.26 2156.13 2318.18 1713.44 2471.34 2358.70 2015.81 9.12 9.57 8.35 -0.23 -0.78 Matched[17]
YAL043C PTA1 "Subunit of holo-CPF, a multiprotein complex and functional homolog of mammalian CPSF, required for the cleavage and polyadenylation of mRNA and snoRNA 3' ends; involved in pre-tRNA processing; binds to the phosphorylated CTD of RNAPII" Verified chr1:58696-61053 58696-61053 98.6% 129.44 134.60 133.31 104.07 92.88 87.29 132.02 118.69 90.09 0.49 0.48 0.37 -0.40 0.27 Matched[18]
YAL042W ERV46 "Protein localized to COPII-coated vesicles, forms a complex with Erv41p; involved in the membrane fusion stage of transport" Verified chr1:61317-62564 61317-62564 98.2% 713.37 742.76 758.26 682.36 433.41 361.58 728.06 720.31 397.50 2.69 2.92 1.65 -0.86 -0.35 Matched[19]
YAL042C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF ERV46/YAL042W; YAL042C-A is a non-essential gene" Dubious chr1:61232-61609 61232-61609 98.3% 371.47 430.69 425.30 390.31 188.43 212.65 401.08 407.81 200.54 1.48 1.66 0.83 -1.02 0.08 Covered/w/another[19]
YAL041W CDC24 "Guanine nucleotide exchange factor (GEF or GDP-release factor) for Cdc42p; required for polarity establishment and maintenance, and mutants have morphological defects in bud formation and shmooing" Verified chr1:62841-65405 62841-65405 98.9% 165.11 180.08 152.10 132.79 139.89 140.68 172.59 142.45 140.28 0.64 0.58 0.58 -0.02 0.39 Matched[20]
YAL040C CLN3 "G1 cyclin involved in cell cycle progression; activates Cdc28p kinase to promote the G1 to S phase transition; plays a role in regulating transcription of the other G1 cyclins, CLN1 and CLN2; regulated by phosphorylation and proteolysis" Verified chr1:65779-67521 65779-67521 98.3% 321.45 259.02 292.28 240.94 201.85 259.02 290.24 266.61 230.44 1.07 1.08 0.95 -0.21 0.43 Matched[22]
YAL039C CYC3 "Cytochrome c heme lyase (holocytochrome c synthase), attaches heme to apo-cytochrome c (Cyc1p or Cyc7p) in the mitochondrial intermembrane space; human ortholog may have a role in microphthalmia with linear skin defects (MLS)" Verified chr1:68717-69526 68717-69526 98.6% 199.11 165.30 255.47 221.65 207.88 152.78 182.21 238.56 180.33 0.67 0.97 0.75 -0.40 -0.33 Matched[24]
YAL038W CDC19 "Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration" Verified chr1:71787-73289 71787-73289 98.8% 28061.87 29476.01 26277.86 25173.62 11775.99 11204.67 28768.94 25725.74 11490.33 106.20 104.43 47.61 -1.16 -2.03 Matched[26]
YAL037C-B "Dubious open reading frame unlikely to encode a protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr1:72327-73301 72327-73301 98.8% 31690.55 33132.92 29417.44 27787.12 13759.09 12242.99 32411.73 28602.29 13001.04 119.65 116.10 53.87 -1.14 NaN Matched[26]
YAL037C-A Putative protein of unknown function Uncharacterized chr1:73427-73519 73427-73519 99.0% 1357.47 1324.89 1020.81 868.78 477.83 249.77 1341.18 944.80 363.80 4.95 3.84 1.51 -1.38 NaN Covered/w/another[26]
YAL037W Putative protein of unknown function Uncharacterized chr1:74021-74824 74021-74824 99.0% 38.95 31.42 28.90 32.67 31.42 15.08 35.19 30.79 23.25 0.13 0.12 0.10 -0.41 -0.95 Matched[27]
YAL036C RBG1 Member of the DRG family of GTP-binding proteins; interacts with translating ribosomes and with Tma46p Verified chr1:75044-76153 75044-76153 99.1% 459.30 284.67 284.67 194.63 60.03 60.03 371.99 239.65 60.03 1.37 0.97 0.25 -2.00 -1.58 Matched[28]
YAL035W FUN12 "GTPase, required for general translation initiation by promoting Met-tRNAiMet binding to ribosomes and ribosomal subunit joining; homolog of bacterial IF2" Verified chr1:76428-79436 76428-79436 97.8% 1022.77 659.32 775.15 787.71 231.66 362.44 841.04 781.43 297.05 3.10 3.17 1.23 -1.40 -0.44 Matched[29]
YAL034W-A MTW1 Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; critical to kinetochore assembly Verified chr1:79719-80588 79719-80588 98.4% 74.76 45.55 75.92 39.71 43.22 26.87 60.15 57.82 35.04 0.22 0.23 0.15 -0.72 -0.28 Matched[30]
YAL034C-B "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr1:79490-79843 79490-79843 99.2% 76.87 62.63 85.41 59.79 31.32 37.01 69.75 72.60 34.16 0.26 0.29 0.14 -1.09 -0.19 Frag<80[30]
YAL034C FUN19 Non-essential protein of unknown function Verified chr1:80711-81952 80711-81952 98.7% 115.03 141.95 121.55 119.11 411.98 391.58 128.49 120.33 401.78 0.47 0.49 1.66 1.74 2.32 Matched[31]
YAL033W POP5 "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends" Verified chr1:82707-83228 82707-83228 98.5% 208.02 134.14 161.36 110.81 124.42 36.94 171.08 136.09 80.68 0.63 0.55 0.33 -0.75 -1.35 Covered/w/another[32]
YAL032C PRP45 Protein required for pre-mRNA splicing; associates with the spliceosome and interacts with splicing factors Prp22p and Prp46p; orthologous to human transcriptional coactivator SKIP and can activate transcription of a reporter gene Verified chr1:83336-84475 83336-84475 99.1% 80.56 95.61 102.70 86.76 115.09 77.02 88.09 94.73 96.06 0.33 0.38 0.40 0.02 0.30 Covered/w/another[32]
YAL031W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr1:84670-84978 84670-84978 98.9% 114.57 137.48 127.66 157.12 219.31 157.12 126.02 142.39 188.22 0.47 0.58 0.78 0.40 NaN Covered/w/another[32]
YAL031C GIP4 Cytoplasmic Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; potential Cdc28p substrate Verified chr1:84750-87032 84750-87032 98.9% 89.50 105.89 101.02 109.88 123.61 120.51 97.69 105.45 122.06 0.36 0.43 0.51 0.21 0.87 Covered/w/another[32]
YAL030W SNC1 Vesicle membrane receptor protein (v-SNARE) involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane; proposed to be involved in endocytosis; member of the synaptobrevin/VAMP family of R-type v-SNARE proteins Verified chr1:87287-87753 87287-87388,87502-87753 98.4% 309.97 424.78 344.42 255.44 797.90 548.19 367.38 299.93 673.04 1.36 1.22 2.79 1.17 0.74 Matched[33]
YAL029C MYO4 "One of two type V myosin motors (along with MYO2) involved in actin-based transport of cargos; required for mRNA transport, including ASH1 mRNA, and facilitating the growth and movement of ER tubules into the growing bud along with She3p" Verified chr1:87856-92271 87856-92271 99.3% 201.41 186.59 153.51 144.39 57.94 82.12 194.00 148.95 70.03 0.72 0.60 0.29 -1.09 -0.61 Matched[34]
YAL028W FRT2 "Tail-anchored endoplasmic reticulum membrane protein, interacts with homolog Frt1p but is not a substrate of calcineurin (unlike Frt1p), promotes growth in conditions of high Na+, alkaline pH, or cell wall stress; potential Cdc28p substrate" Verified chr1:92901-94487 92901-94487 98.8% 54.86 139.70 66.34 85.48 206.04 194.56 97.28 75.91 200.30 0.36 0.31 0.83 1.40 1.12 Matched[35]
YAL027W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YAL027W is a non-essential gene Uncharacterized chr1:94688-95473 94688-95473 98.8% 85.00 99.17 81.14 83.71 96.59 60.53 92.08 82.43 78.56 0.34 0.33 0.33 -0.07 -0.04 Matched[36]
YAL026C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YAL027W and the verified gene DRS2" Dubious chr1:95387-95824 95387-95824 99.3% 407.05 365.66 335.76 287.47 388.65 179.38 386.35 311.61 284.02 1.43 1.26 1.18 -0.13 NaN
YAL026C DRS2 Aminophospholipid translocase (flippase) that maintains membrane lipid asymmetry in post-Golgi secretory vessicles; contributes to clathrin-coated vesicle formation and endocytosis; mutations in human homolog ATP8B1 result in liver disease Verified chr1:95631-99698 95631-99698 99.1% 186.01 172.37 162.95 152.53 106.65 108.38 179.19 157.74 107.52 0.66 0.64 0.45 -0.55 -0.13 Frag>80[37,38,39]
YAL025C MAK16 "Essential nuclear protein, constituent of 66S pre-ribosomal particles; required for maturation of 25S and 5.8S rRNAs; required for maintenance of M1 satellite double-stranded RNA of the L-A virus" Verified chr1:100226-101146 100226-101146 99.5% 355.85 210.67 239.05 162.64 12.01 10.92 283.26 200.85 11.46 1.05 0.82 0.05 -4.13 -4.21 Frag>80[39,40]
YAL024C LTE1 "Putative GDP/GTP exchange factor required for mitotic exit at low temperatures; acts as a guanine nucleotide exchange factor (GEF) for Tem1p, which is a key regulator of mitotic exit; physically associates with Ras2p-GTP" Verified chr1:101566-105873 101566-105873 99.2% 57.57 49.62 41.42 43.30 31.13 33.00 53.59 42.36 32.06 0.20 0.17 0.13 -0.40 0.03 Matched[41]
YAL023C PMT2 "Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt1p, can instead interact with Pmt5p in some conditions; target for new antifungals" Verified chr1:106273-108552 106273-108552 98.6% 837.27 699.35 871.97 746.51 535.64 654.42 768.31 809.24 595.03 2.84 3.28 2.47 -0.44 0.22 Frag>80[42,43]
YAL022C FUN26 Nucleoside transporter with broad nucleoside selectivity; localized to intracellular membranes Verified chr1:108878-110431 108878-110431 98.5% 189.37 166.52 191.33 148.89 174.35 124.07 177.94 170.11 149.21 0.66 0.69 0.62 -0.19 0.06 Matched[44]
YAL021C CCR4 "Component of the CCR4-NOT transcriptional complex, which is involved in regulation of gene expression; component of the major cytoplasmic deadenylase, which is involved in mRNA poly(A) tail shortening" Verified chr1:110847-113360 110847-113360 97.7% 216.97 194.99 193.77 197.02 132.71 178.30 205.98 195.40 155.50 0.76 0.79 0.64 -0.33 0.33 Matched[45]
YAL019W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr1:114251-114820 114251-114820 99.3% 47.70 38.87 51.24 45.94 53.00 31.80 43.29 48.59 42.40 0.16 0.20 0.18 -0.20 NaN Frag<80[46]
YAL020C ATS1 "Protein required, with Elongator complex, Kti11p, and Kti12p, for modification of wobble nucleosides in tRNA; has a potential role in regulatory interactions between microtubules and the cell cycle" Verified chr1:113615-114616 113615-114616 98.8% 89.86 84.81 90.87 72.70 96.93 53.51 87.34 81.78 75.22 0.32 0.33 0.31 -0.12 0.23 Matched[46]
YAL019W FUN30 "Protein whose overexpression affects chromosome stability, potential Cdc28p substrate; homolog of Snf2p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr1:114920-118315 114920-118315 98.6% 157.44 116.81 110.24 103.66 24.20 32.86 137.12 106.95 28.53 0.51 0.43 0.12 -1.91 -1.41 Matched[47]
YAL018C Putative protein of unknown function Uncharacterized chr1:118565-119542 118565-119542 99.0% 0.00 1.03 2.07 1.03 7.23 6.20 0.52 1.55 6.71 0.00 0.01 0.03 2.12 0.84
YAL017W PSK1 One of two (see also PSK2) PAS domain containing S/T protein kinases; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status Verified chr1:120226-124296 120226-124296 98.6% 142.76 183.13 172.66 195.83 241.43 323.40 162.94 184.25 282.41 0.60 0.75 1.17 0.62 1.50 Matched[48]
YAL016C-B "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr1:124308-124493 124308-124493 99.4% 194.81 335.51 270.58 238.11 660.20 432.92 265.16 254.34 546.56 0.98 1.03 2.26 1.10 NaN Covered/w/another[48]
YAL016W TPD3 "Regulatory subunit A of the heterotrimeric protein phosphatase 2A, which also contains regulatory subunit Cdc55p and either catalytic subunit Pph21p or Pph22p; required for cell morphogenesis and for transcription by RNA polymerase III" Verified chr1:124880-126787 124880-126787 98.9% 347.07 321.63 375.15 322.16 493.31 429.20 334.35 348.66 461.25 1.23 1.42 1.91 0.40 0.89 Matched[49]
YAL016C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr1:124756-125070 124756-125070 98.4% 135.45 119.32 161.25 183.82 161.25 206.40 127.39 172.53 183.82 0.47 0.70 0.76 0.09 NaN Covered/w/another[49]
YAL015C NTG1 "DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision repair, localizes to the nucleus and mitochondrion" Verified chr1:126904-128103 126904-128103 99.1% 103.41 110.98 118.55 83.23 258.95 145.45 107.20 100.89 202.20 0.40 0.41 0.84 1.00 0.66 Matched[50]
YAL014C SYN8 Endosomal SNARE related to mammalian syntaxin 8 Verified chr1:128253-129020 128253-129020 99.0% 281.55 259.18 240.76 157.88 353.91 228.92 270.37 199.32 291.42 1.00 0.81 1.21 0.55 0.71 Matched[51]
YAL013W DEP1 "Transcriptional modulator involved in regulation of structural phospholipid biosynthesis genes and metabolically unrelated genes, as well as maintenance of telomeres, mating efficiency, and sporulation" Verified chr1:129271-130533 129271-130533 97.8% 111.70 131.13 140.84 111.70 145.69 125.46 121.41 126.27 135.58 0.45 0.51 0.56 0.10 0.65 Matched[52]
YAL012W CYS3 "Cystathionine gamma-lyase, catalyzes one of the two reactions involved in the transsulfuration pathway that yields cysteine from homocysteine with the intermediary formation of cystathionine" Verified chr1:130802-131986 130802-131986 98.8% 1032.86 1051.65 1133.66 996.97 782.54 754.35 1042.25 1065.32 768.45 3.85 4.32 3.18 -0.47 0.27 Matched[53]
YAL011W SWC3 "Protein of unknown function, component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required for formation of nuclear-associated array of smooth endoplasmic reticulum known as karmellae" Verified chr1:132202-134079 132202-134079 98.1% 79.25 93.90 78.16 71.11 53.74 42.88 86.57 74.63 48.31 0.32 0.30 0.20 -0.63 -0.21 Covered/w/another[54]
YAL010C MDM10 Subunit of both the Mdm10-Mdm12-Mmm1 complex and the mitochondrial sorting and assembly machinery (SAM complex); functions in both the general and Tom40p-specific pathways for import and assembly of outer membrane beta-barrel proteins Verified chr1:134186-135667 134186-135667 99.1% 49.02 64.00 44.93 43.57 88.51 72.85 56.51 44.25 80.68 0.21 0.18 0.33 0.87 0.80 Covered/w/another[54]
YAL009W SPO7 "Regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme, which regulates nuclear growth by controlling recruitment of Pah1p onto promoters of phospholipid biosynthetic genes; required for normal nuclear envelope morphology and sporulation" Verified chr1:135856-136635 135856-136635 98.6% 106.64 143.05 120.94 114.44 114.44 117.04 124.84 117.69 115.74 0.46 0.48 0.48 -0.02 0.05 Frag>80[55,56]
YAL008W FUN14 Mitochondrial protein of unknown function Verified chr1:136916-137512 136916-137512 98.6% 247.98 434.82 263.27 336.31 988.54 681.10 341.40 299.79 834.82 1.26 1.22 3.46 1.48 0.64 Matched[57]
YAL007C ERP2 "Protein that forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles" Verified chr1:137700-138347 137700-138347 99.0% 821.19 758.86 805.61 709.00 609.27 451.89 790.03 757.30 530.58 2.92 3.07 2.20 -0.51 -0.19 Frag>80[58,59]
YAL004W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps verified gene SSA1/YAL005C" Dubious chr1:140762-141409 140762-141409 34.1% 1649.72 2928.81 2051.98 2345.76 11823.73 11665.54 2289.27 2198.87 11744.63 8.45 8.93 48.66 2.42 -0.04 Frag<80[61,62,63,64,65]
YAL005C SSA1 "ATPase involved in protein folding and nuclear localization signal (NLS)-directed nuclear transport; member of heat shock protein 70 (HSP70) family; forms a chaperone complex with Ydj1p; localized to the nucleus, cytoplasm, and cell wall" Verified chr1:139505-141433 139505-141433 26.9% 2946.02 5223.01 3726.86 4043.06 33156.17 19289.85 4084.51 3884.96 26223.01 15.08 15.77 108.65 2.75 2.33 Frag<80[60,61,62,63,64,65]
YAL003W EFB1 "Translation elongation factor 1 beta; stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle; part of the EF-1 complex, which facilitates binding of aminoacyl-tRNA to the ribosomal A site" Verified chr1:142176-143162 142176-142255,142622-143162 98.6% 8897.54 6603.35 8458.29 7401.82 12692.34 11500.34 7750.44 7930.06 12096.34 28.61 32.19 50.12 0.61 0.10 Frag>80[65,66,67,68]
YAL002W VPS8 Membrane-associated protein that interacts with Vps21p to facilitate soluble vacuolar protein localization; component of the CORVET complex; required for localization and trafficking of the CPY sorting receptor; contains RING finger motif Verified chr1:143709-147533 143709-147533 99.0% 67.86 92.41 83.44 66.54 73.67 64.16 80.14 74.99 68.91 0.30 0.30 0.29 -0.12 0.21 Matched[69]
YAL001C TFC3 Largest of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauB domain of TFIIIC that binds DNA at the BoxB promoter sites of tRNA and similar genes; cooperates with Tfc6p in DNA binding Verified chr1:147596-151168 147596-151008,151099-151168 99.3% 138.76 158.70 125.75 125.17 111.87 111.29 148.73 125.46 111.58 0.55 0.51 0.46 -0.17 0.18 Matched[70]
YAR002W NUP60 "Subunit of the nuclear pore complex (NPC), functions to anchor Nup2p to the NPC in a process controlled by the nucleoplasmic concentration of Gsp1p-GTP; potential Cdc28p substrate; involved in telomere maintenance" Verified chr1:152259-153878 152259-153878 98.8% 254.30 249.93 253.05 246.80 126.84 121.84 252.12 249.93 124.34 0.93 1.01 0.52 -1.01 -0.41 Matched[71]
YAR002C-A ERP1 "Protein that forms a heterotrimeric complex with Erp2p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles" Verified chr1:154067-154726 154067-154726 99.0% 1085.27 972.00 1008.74 1016.39 733.21 606.16 1028.64 1012.56 669.69 3.80 4.11 2.77 -0.60 -0.59 Frag>80[72,73]
YAR003W SWD1 "Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member with similarity to mammalian Rbbp7" Verified chr1:155007-156287 155007-156287 98.6% 151.96 178.87 113.18 115.56 123.47 66.48 165.42 114.37 94.98 0.61 0.46 0.39 -0.27 -1.27 Matched[74]
YAR007C RFA1 "Subunit of heterotrimeric Replication Protein A (RPA), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination" Verified chr1:156756-158621 156756-158621 99.1% 244.50 190.40 235.30 258.02 255.31 213.66 217.45 246.66 234.49 0.80 1.00 0.97 -0.07 0.27 Matched[75]
YAR008W SEN34 "Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen34p contains the active site for tRNA 3' splice site cleavage and has similarity to Sen2p and to Archaeal tRNA splicing endonuclease" Verified chr1:158967-159794 158967-159794 98.6% 129.84 97.99 101.66 74.72 33.07 15.92 113.91 88.19 24.50 0.42 0.36 0.10 -1.85 -2.12 Matched[76]
YAR014C BUD14 "Protein involved in bud-site selection, Bud14p-Glc7p complex functions as a cortical regulator of dynein; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern" Verified chr1:166743-168866 166743-168866 99.2% 170.94 147.67 153.37 137.70 100.66 90.69 159.30 145.53 95.68 0.59 0.59 0.40 -0.61 -0.24 Frag>80[78,79]
YAR015W ADE1 "N-succinyl-5-aminoimidazole-4-carboxamide ribotide (SAICAR) synthetase, required for 'de novo' purine nucleotide biosynthesis; red pigment accumulates in mutant cells deprived of adenine" Verified chr1:169370-170290 169370-170290 98.6% 3013.35 2268.83 2878.99 2300.77 501.12 259.92 2641.09 2589.88 380.52 9.75 10.51 1.58 -2.77 -2.35 Matched[80]
YAR018C KIN3 Nonessential protein kinase with unknown cellular role Verified chr1:170391-171698 170391-171698 99.2% 122.48 102.46 114.01 104.77 136.35 98.60 112.47 109.39 117.48 0.42 0.44 0.49 0.10 0.37
YAR019W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr1:174996-175340 174996-175340 98.5% 5.88 2.94 8.82 14.71 17.65 38.24 4.41 11.77 27.94 0.02 0.05 0.12 1.25 NaN Overlap[81,82]
YAR019C CDC15 Protein kinase of the Mitotic Exit Network that is localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p Verified chr1:172209-175133 172209-175133 98.8% 35.29 31.83 41.17 44.29 78.89 83.73 33.56 42.73 81.31 0.12 0.17 0.34 0.93 1.51 Covered/w/another[81]
YAR020C PAU7 "Part of 23-member seripauperin multigene family, active during alcoholic fermentation, regulated by anaerobiosis, inhibited by oxygen, repressed by heme" Verified chr1:176854-177021 176854-177021 37.8% 15.74 94.43 31.48 31.48 110.16 78.69 55.08 31.48 94.43 0.20 0.13 0.39 1.58 1.16 Covered/w/another[84]
YAR023C "Putative integral membrane protein, member of DUP240 gene family" Uncharacterized chr1:179279-179818 179279-179818 99.1% 37.38 56.07 44.86 37.38 104.67 67.29 46.73 41.12 85.98 0.17 0.17 0.36 1.06 1.35 Covered/w/another[84]
YAR027W UIP3 Putative integral membrane protein of unknown function; interacts with Ulp1p at the nuclear periphery; member of DUP240 gene family Verified chr1:183764-184471 183764-184471 95.8% 257.95 346.39 344.92 365.56 937.48 613.19 302.17 355.24 775.33 1.12 1.44 3.21 1.13 1.08 Matched[86]
YAR028W "Putative integral membrane protein, member of DUP240 gene family; GFP-fusion protein is induced in response to the DNA-damaging agent MMS" Uncharacterized chr1:184886-185590 184886-185590 96.1% 165.34 258.35 131.39 147.63 150.58 125.48 211.85 139.51 138.03 0.78 0.57 0.57 -0.02 0.39 Matched[87]
YAR029W Member of DUP240 gene family but contains no transmembrane domains; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern Uncharacterized chr1:186315-186539 186315-186539 98.3% 67.81 135.62 49.73 31.64 140.14 58.77 101.71 40.69 99.45 0.38 0.17 0.41 1.29 2.08 Covered/w/another[88]
YAR031W PRM9 "Pheromone-regulated protein with 3 predicted transmembrane segments and an FF sequence, a motif involved in COPII binding; member of DUP240 gene family" Verified chr1:186830-187726 186830-187726 62.3% 55.46 62.62 50.10 37.57 53.68 42.94 59.04 43.83 48.31 0.22 0.18 0.20 0.14 0.56 Overlap[88]
YAR030C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YAR029W and the verified gene PRM9" Dubious chr1:186506-186847 186506-186847 99.0% 32.49 47.26 17.72 11.82 56.12 44.31 39.88 14.77 50.22 0.15 0.06 0.21 1.77 0.47 Covered/w/another[88]
YAR033W MST28 "Putative integral membrane protein, involved in vesicle formation; forms complex with Mst27p; member of DUP240 gene family; binds COPI and COPII vesicles" Verified chr1:188101-188805 188101-188805 11.5% 99.07 160.99 49.54 24.77 24.77 61.92 130.03 37.15 43.34 0.48 0.15 0.18 0.22 -0.07
YAR035W YAT1 "Outer mitochondrial carnitine acetyltransferase, minor ethanol-inducible enzyme involved in transport of activated acyl groups from the cytoplasm into the mitochondrial matrix; phosphorylated" Verified chr1:190187-192250 190187-192250 98.3% 13.31 22.19 14.79 14.30 24.65 27.12 17.75 14.55 25.89 0.07 0.06 0.11 0.83 0.59 Overlap[91]
YAR035C-A "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr1:192331-192411 192331-192411 98.9% 37.44 24.96 12.48 0.00 12.48 62.40 31.20 6.24 37.44 0.12 0.03 0.16 2.58 NaN Covered/w/another[91]
YAR042W SWH1 Protein similar to mammalian oxysterol-binding protein; contains ankyrin repeats; localizes to the Golgi and the nucleus-vacuole junction Verified chr1:192613-196179 192613-196179 98.2% 164.39 168.95 169.81 157.82 162.10 248.58 166.67 163.81 205.34 0.62 0.66 0.85 0.33 1.25 Covered/w/another[91]
YAR047C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr1:201460-201780 201460-201780 99.0% 9.44 9.44 3.15 3.15 15.74 3.15 9.44 3.15 9.44 0.03 0.01 0.04 1.58 -0.40
YAR050W FLO1 "Lectin-like protein involved in flocculation, cell wall protein that binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin sensitive and heat resistant; similar to Flo5p" Verified chr1:203394-208007 203394-208007 21.5% 18.17 21.20 20.19 10.09 9.08 10.09 19.68 15.14 9.59 0.07 0.06 0.04 -0.66 1.01 Frag<80[94]
YAR053W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr1:208358-208654 208358-208654 18.6% 0.00 18.13 0.00 0.00 0.00 18.13 9.06 0.00 9.06 0.03 0.00 0.04 Inf 0.46
YAR060C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr1:217148-217483 217148-217483 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.64
YAR064W Putative protein of unknown function Uncharacterized chr1:220189-220488 220189-220488 4.0% 0.00 84.21 84.21 168.42 0.00 0.00 42.11 126.32 0.00 0.16 0.51 0.00 -Inf -0.16
YAR066W Putative GPI protein Uncharacterized chr1:221040-221651 221040-221651 1.0% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.01
YAR068W Fungal-specific protein of unknown function; induced in respiratory-deficient cells Uncharacterized chr1:222397-222882 222397-222882 1.2% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN -0.06
YAR069C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr1:224002-224295 224002-224295 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -1.12
YAR070C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr1:224554-224853 224554-224853 11.2% 0.00 0.00 0.00 29.85 0.00 0.00 0.00 14.93 0.00 0.00 0.06 0.00 -Inf -1.11
YAR071W PHO11 "One of three repressible acid phosphatases, a glycoprotein that is transported to the cell surface by the secretory pathway; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2" Verified chr1:225451-226854 225451-226854 2.8% 450.00 175.00 250.00 250.00 0.00 75.00 312.50 250.00 37.50 1.15 1.01 0.16 -2.74 -1.88 Frag<80[95]
YAR073W IMD1 "Nonfunctional protein with homology to IMP dehydrogenase; probable pseudogene, located close to the telomere; is not expressed at detectable levels; YAR073W and YAR075W comprise a continuous reading frame in some strains of S. cerevisiae" Dubious chr1:227733-228944 227733-228944 17.9% 4.62 9.24 4.62 0.00 0.00 0.00 6.93 2.31 0.00 0.03 0.01 0.00 -Inf -2.13
YAR075W Non-functional protein with homology IMP dehydrogenase; YAR073W/IMD1 and YAR075W comprise a continuous reading frame in some strains of S. cerevisiae. Dubious chr1:228835-229308 228835-229308 37.7% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN -1.94
YBL113W-A "Dubious open reading frame unlikely to encode a protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr2:646-1128 646-1128 1.3% 155.84 0.00 155.84 0.00 0.00 0.00 77.92 77.92 0.00 0.29 0.32 0.00 -Inf NaN
YBL113C Helicase-like protein encoded within the telomeric Y' element Uncharacterized chr2:280-2658 280-2658 3.0% 69.57 97.39 41.74 13.91 41.74 41.74 83.48 27.83 41.74 0.31 0.11 0.17 0.58 0.22
YBL112C Putative protein of unknown function; YBL112C is contained within TEL02L Uncharacterized chr2:2582-2899 2582-2899 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.05
YBL111C Helicase-like protein encoded within the telomeric Y' element Uncharacterized chr2:2907-5009 2907-4116,4216-5009 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.41
YBL109W "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data" Dubious chr2:5790-6125 5790-6125 45.9% 12.97 6.48 12.97 0.00 6.48 0.00 9.72 6.48 3.24 0.04 0.03 0.01 -1.00 -0.37
YBL108C-A Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36. Uncharacterized chr2:7605-7733 7605-7733 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.67
YBL108W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr2:8177-8482 8177-8482 50.4% 6.48 6.48 6.48 0.00 0.00 0.00 6.48 3.24 0.00 0.02 0.01 0.00 -Inf -0.05 Frag<80[96,97,98]
YBL107W-A Similar to TyA and TyB proteins Dubious chr2:9268-9372 9268-9372 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.23
YBL107C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YBL107C is not an essential gene Uncharacterized chr2:9961-10551 9961-10551 99.5% 347.04 282.39 278.99 222.85 275.59 124.18 314.72 250.92 199.89 1.16 1.02 0.83 -0.33 -0.44 Matched[99]
YBL106C SRO77 Protein with roles in exocytosis and cation homeostasis; functions in docking and fusion of post-Golgi vesicles with plasma membrane; homolog of Sro7p and Drosophila lethal giant larvae tumor suppressor; interacts with SNARE protein Sec9p Verified chr2:10847-13879 10847-13879 99.1% 44.23 54.88 38.58 25.94 25.28 14.30 49.55 32.26 19.79 0.18 0.13 0.08 -0.71 -0.70 Frag>80[100,101]
YBL105C PKC1 "Protein serine/threonine kinase essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC)" Verified chr2:14241-17696 14241-17696 99.2% 141.52 149.98 138.02 140.93 89.58 106.50 145.75 139.48 98.04 0.54 0.57 0.41 -0.51 0.01 Matched[102]
YBL104C "Putative protein of unknown function, promoter contains multiple GCN4 binding sites" Uncharacterized chr2:18177-21293 18177-21293 99.2% 80.53 75.35 70.50 62.09 42.69 41.40 77.94 66.30 42.04 0.29 0.27 0.17 -0.66 0.05 Matched[103]
YBL103C RTG3 "Basic helix-loop-helix-leucine zipper (bHLH/Zip) transcription factor that forms a complex with another bHLH/Zip protein, Rtg1p, to activate the retrograde (RTG) and TOR pathways" Verified chr2:22075-23535 22075-23535 98.9% 99.63 136.30 91.33 88.56 98.94 71.27 117.97 89.95 85.10 0.44 0.37 0.35 -0.08 0.13 Matched[104]
YBL102W SFT2 "Non-essential tetra-spanning membrane protein found mostly in the late Golgi, can suppress some sed5 alleles; may be part of the transport machinery, but precise function is unknown; similar to mammalian syntaxin 5" Verified chr2:24098-24745 24098-24745 98.9% 513.49 594.65 554.07 461.99 948.95 613.38 554.07 508.03 781.17 2.05 2.06 3.24 0.62 0.23 Matched[105]
YBL101C ECM21 Non-essential protein of unknown function; promoter contains several Gcn4p binding elements Verified chr2:24946-28299 24946-28299 98.9% 113.67 107.04 138.09 131.46 147.14 179.40 110.35 134.77 163.27 0.41 0.55 0.68 0.28 0.84 Matched[106]
YBL100W-C "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr2:28427-28546 28427-28546 98.4% 25.41 33.89 8.47 33.89 59.30 42.36 29.65 21.18 50.83 0.11 0.09 0.21 1.26 NaN Covered/w/another[106]
YBL099W ATP1 "Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated" Verified chr2:37050-38687 37050-38687 98.7% 2333.02 2605.16 2390.54 2794.42 2108.50 2571.76 2469.09 2592.48 2340.13 9.11 10.52 9.70 -0.15 -0.40 Matched[107]
YBL100C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; almost completely overlaps the 5' end of ATP1" Dubious chr2:36986-37300 36986-37300 98.6% 1149.30 1487.32 1329.58 1664.39 1033.40 1686.92 1318.31 1496.98 1360.16 4.87 6.08 5.64 -0.14 0.07 Covered/w/another[107]
YBL098W BNA4 "Kynurenine 3-mono oxygenase, required for biosynthesis of nicotinic acid from tryptophan via kynurenine pathway" Verified chr2:39142-40524 39142-40524 98.9% 206.89 210.55 188.61 163.03 100.89 57.02 208.72 175.82 78.95 0.77 0.71 0.33 -1.16 -1.14 Matched[108]
YBL097W BRN1 "Essential protein required for chromosome condensation, likely to function as an intrinsic component of the condensation machinery, may influence multiple aspects of chromosome transmission and dynamics" Verified chr2:40828-43092 40828-43092 98.4% 46.65 35.89 30.95 35.44 13.46 27.81 41.27 33.19 20.63 0.15 0.13 0.09 -0.69 0.18 Matched[109]
YBL095W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr2:43274-44086 43274-44086 98.4% 152.55 137.54 156.30 101.28 191.31 133.79 145.05 128.79 162.55 0.54 0.52 0.67 0.34 0.33 Covered/w/another[110]
YBL096C Non-essential protein of unknown function Dubious chr2:43171-43479 43171-43479 98.2% 102.13 52.71 115.31 56.01 118.60 65.89 77.42 85.66 92.24 0.29 0.35 0.38 0.11 0.19 Covered/w/another[110]
YBL094C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps uncharacterized ORF YBL095W" Dubious chr2:43762-44094 43762-44094 98.6% 203.98 188.76 179.63 121.78 210.07 164.40 196.37 150.70 187.24 0.72 0.61 0.78 0.31 0.10 Covered/w/another[110]
YBL093C ROX3 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme Verified chr2:44253-44915 44253-44915 99.1% 249.70 278.63 237.52 216.20 214.68 115.71 264.16 226.86 165.20 0.98 0.92 0.68 -0.46 -0.25 Covered/w/another[110]
YBL092W RPL32 "Protein component of the large (60S) ribosomal subunit, has similarity to rat L32 ribosomal protein; overexpression disrupts telomeric silencing" Verified chr2:45641-46367 45641-45642,45975-46367 98.7% 13871.91 11583.02 12753.13 11008.23 3818.24 2897.04 12727.47 11880.68 3357.64 46.98 48.23 13.91 -1.82 -1.86 Matched[111]
YBL091C-A SCS22 Protein involved in regulation of phospholipid metabolism; homolog of Scs2p; similar to D. melanogaster inturned protein Verified chr2:46562-47177 46562-47055,47144-47177 99.0% 214.35 275.60 214.35 183.73 311.96 166.51 244.98 199.04 239.23 0.90 0.81 0.99 0.27 -0.40 Matched[112]
YBL091C MAP2 "Methionine aminopeptidase, catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p" Verified chr2:47360-48625 47360-48625 98.8% 699.39 763.34 681.81 673.02 728.97 581.90 731.37 677.41 655.43 2.70 2.75 2.72 -0.05 0.15 Matched[113]
YBL090W MRP21 Mitochondrial ribosomal protein of the large subunit; MRP21 exhibits genetic interactions with mutations in the COX2 and COX3 mRNA 5'-untranslated leader sequences Verified chr2:48822-49355 48822-49355 98.5% 294.70 247.17 269.98 287.09 361.25 199.64 270.93 278.54 280.44 1.00 1.13 1.16 0.01 -0.47 Matched[114]
YBL089W AVT5 "Putative transporter, member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters" Verified chr2:49571-50950 49571-50950 99.0% 89.99 104.62 103.89 78.28 84.87 53.41 97.31 91.09 69.14 0.36 0.37 0.29 -0.40 -0.42 Covered[115]
YBL088C TEL1 Protein kinase primarily involved in telomere length regulation; contributes to cell cycle checkpoint control in response to DNA damage; functionally redundant with Mec1p; homolog of human ataxia telangiectasia (ATM) gene Verified chr2:51016-59379 51016-59379 99.2% 39.91 49.92 30.63 28.34 15.68 24.24 44.92 29.48 19.96 0.17 0.12 0.08 -0.56 -0.26 Overlap[115]
YBL087C RPL23A "Protein component of the large (60S) ribosomal subunit, identical to Rpl23Bp and has similarity to E. coli L14 and rat L23 ribosomal proteins" Verified chr2:59818-60735 59818-60189,60694-60735 60.9% 4777.78 4313.49 4698.41 4170.64 1309.52 1170.64 4545.64 4434.52 1240.08 16.78 18.00 5.14 -1.84 -1.86 Matched[116]
YBL086C Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery Uncharacterized chr2:61199-62599 61199-62599 99.2% 119.45 123.05 141.04 156.87 267.69 238.19 121.25 148.96 252.94 0.45 0.60 1.05 0.76 1.13 Matched[117]
YBL085W BOI1 "Protein implicated in polar growth, functionally redundant with Boi2p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain" Verified chr2:63873-66815 63873-66815 98.5% 243.45 245.18 265.52 239.31 233.80 220.35 244.31 252.42 227.07 0.90 1.02 0.94 -0.15 0.36 Matched[119]
YBL084C CDC27 "Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" Verified chr2:67166-69442 67166-69442 96.7% 80.38 64.48 65.39 74.93 133.96 105.81 72.43 70.16 119.89 0.27 0.28 0.50 0.77 0.45 Matched[120]
YBL083C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps verified ORF ALG3" Dubious chr2:69710-70135 69710-70135 97.8% 244.85 196.84 196.84 187.24 62.41 64.81 220.84 192.04 63.61 0.82 0.78 0.26 -1.59 -0.95 Covered/w/another[121]
YBL082C ALG3 "Dolichol-P-Man dependent alpha(1-3) mannosyltransferase, involved in the synthesis of dolichol-linked oligosaccharide donor for N-linked glycosylation of proteins" Verified chr2:69748-71124 69748-71124 98.3% 183.21 161.79 157.36 155.14 53.93 48.76 172.50 156.25 51.34 0.64 0.63 0.21 -1.61 -1.06 Matched[121]
YBL081W Non-essential protein of unknown function Uncharacterized chr2:71863-72969 71863-72969 96.1% 222.72 149.42 169.15 123.11 41.35 39.47 186.07 146.13 40.41 0.69 0.59 0.17 -1.85 -1.08 Matched[122]
YBL080C PET112 Protein required for mitochondrial translation; mutation is functionally complemented by a Bacillus subtilis ortholog Verified chr2:73067-74692 73067-74692 99.1% 53.36 53.98 52.74 52.74 90.59 51.50 53.67 52.74 71.04 0.20 0.21 0.29 0.43 0.69 Matched[123]
YBL079W NUP170 "Abundant subunit of the nuclear pore complex (NPC), required for proper localization of specific nucleoporins within the NPC, involved in nuclear envelope permeability and in chromosome segregation, has similarity to Nup157p" Verified chr2:75256-79764 75256-79764 99.0% 133.51 115.59 116.49 103.05 45.25 67.65 124.55 109.77 56.45 0.46 0.45 0.23 -0.96 -0.39 Matched[124]
YBL078C ATG8 "Protein required for autophagy; modified by the serial action of Atg4p, Atg7p, and Atg3p, and conjugated at the C terminus with phosphatidylethanolamine, to become the form essential for generation of autophagosomes" Verified chr2:80375-80728 80375-80728 99.1% 228.14 327.95 327.95 265.21 1770.91 1117.87 278.04 296.58 1444.39 1.03 1.20 5.98 2.28 1.83 Matched[125]
YBL077W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene ILS1/YBL076C" Dubious chr2:80895-81326 80895-81326 99.4% 1804.77 1434.50 1504.37 1339.03 409.86 200.27 1619.64 1421.70 305.07 5.98 5.77 1.26 -2.22 -1.01 Matched[126]
YBL076C ILS1 "Cytoplasmic isoleucine-tRNA synthetase, target of the G1-specific inhibitor reveromycin A" Verified chr2:81041-84259 81041-84259 99.0% 1050.82 941.28 982.08 955.09 182.67 167.60 996.05 968.59 175.14 3.68 3.93 0.73 -2.47 -1.70 Frag>80[126,127,128,129]
YBL075C SSA3 ATPase involved in protein folding and the response to stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm Verified chr2:84497-86446 84497-86446 99.0% 53.85 74.04 52.81 53.33 1330.08 1422.76 63.94 53.07 1376.42 0.24 0.22 5.70 4.70 4.53 Frag>80[129,130]
YBL073W Hypothetical protein; open reading frame overlaps 5' end of essential AAR2 gene encoding a component of the U5 snRNP required for splicing of U3 precursors Dubious chr2:87644-87955 87644-87955 99.0% 19.43 22.67 12.95 16.19 6.48 35.62 21.05 14.57 21.05 0.08 0.06 0.09 0.53 0.62 Overlap[131]
YBL074C AAR2 "Component of the U5 snRNP, required for splicing of U3 precursors; originally described as a splicing factor specifically required for splicing pre-mRNA of the MATa1 cistron" Verified chr2:86720-87787 86720-87787 99.2% 35.87 37.76 23.60 18.88 27.37 52.86 36.81 21.24 40.11 0.14 0.09 0.17 0.92 1.68 Matched[131]
YBL072C RPS8A Protein component of the small (40S) ribosomal subunit; identical to Rps8Bp and has similarity to rat S8 ribosomal protein Verified chr2:88521-89439 88521-89130,89438-89439 21.4% 8492.19 7497.61 7765.38 7688.88 2027.41 2409.95 7994.90 7727.13 2218.68 29.51 31.37 9.19 -1.80 -3.24 Frag<80[132,133]
YBL071C-B "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr2:89456-89554 89456-89554 98.9% 40.85 40.85 10.21 10.21 0.00 10.21 40.85 10.21 5.11 0.15 0.04 0.02 -1.00 NaN Matched[133]
YBL071W-A KTI11 "Protein required for synthesis of diphthamide, a modified histidine residue of translation elongation factor 2; functions with Dph1p, Dph2p, Jjj3p, and Dph5p; required, with Elongator complex, for modification of wobble nucleosides in tRNA" Verified chr2:89976-90224 89976-90224 98.6% 175.21 114.09 69.27 81.49 73.34 32.60 144.65 75.38 52.97 0.53 0.31 0.22 -0.51 -0.37 Covered/w/another[134]
YBL071C "Dubious open reading frame, predicted protein contains a peroxisomal targeting signal" Dubious chr2:90221-90529 90221-90529 99.0% 130.77 134.04 120.96 55.58 35.96 35.96 132.41 88.27 35.96 0.49 0.36 0.15 -1.30 -0.62 Covered/w/another[134]
YBL069W AST1 "Peripheral membrane protein that interacts with the plasma membrane ATPase Pma1p and has a role in its targeting to the plasma membrane, possibly by influencing its incorporation into lipid rafts" Verified chr2:90739-92028 90739-92028 98.7% 117.79 139.77 114.64 95.01 69.10 62.82 128.78 104.83 65.96 0.48 0.43 0.27 -0.67 -0.35 Covered/w/another[134]
YBL070C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr2:90603-90923 90603-90923 98.9% 63.03 100.84 72.48 63.03 25.21 37.82 81.93 67.75 31.51 0.30 0.28 0.13 -1.10 -0.25 Covered/w/another[134]
YBL068W-A Dubious open reading frame unlikely to encode a protein; identified by fungal homology and RT-PCR Dubious chr2:91792-92028 91792-92028 98.9% 200.46 166.34 149.28 123.69 140.75 72.51 183.40 136.48 106.63 0.68 0.55 0.44 -0.36 NaN Covered/w/another[134]
YBL068W PRS4 "5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes" Verified chr2:92412-93395 92412-93395 98.7% 225.39 153.34 167.75 125.56 39.11 22.64 189.37 146.66 30.87 0.70 0.60 0.13 -2.25 -1.94 Covered/w/another[135]
YBL067C UBP13 "Putative ubiquitin carboxyl-terminal hydrolase, ubiquitin-specific protease that cleaves ubiquitin-protein fusions" Verified chr2:93641-95884 93641-95884 99.2% 154.05 137.43 117.22 104.20 87.13 92.52 145.74 110.71 89.82 0.54 0.45 0.37 -0.30 -0.15 Covered/w/another[135]
YBL065W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF SEF1/YBL066C; YBL065W is a non-essential gene" Dubious chr2:99965-100309 99965-100309 98.8% 8.80 32.27 20.54 8.80 46.94 26.41 20.54 14.67 36.67 0.08 0.06 0.15 1.32 0.76 Overlap[136,137]
YBL066C SEF1 "Putative transcription factor, has homolog in Kluyveromyces lactis" Verified chr2:96671-100117 96671-100117 98.8% 40.83 50.52 39.65 45.53 26.14 39.07 45.67 42.59 32.60 0.17 0.17 0.14 -0.39 0.51 Matched[136]
YBL064C PRX1 "Mitochondrial peroxiredoxin (1-Cys Prx) with thioredoxin peroxidase activity, has a role in reduction of hydroperoxides; induced during respiratory growth and under conditions of oxidative stress; phosphorylated" Verified chr2:100373-101158 100373-101158 98.9% 477.27 657.38 670.24 626.50 2607.63 1981.13 567.32 648.37 2294.38 2.09 2.63 9.51 1.82 2.07 Matched[137]
YBL063W KIP1 Kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation; functionally redundant with Cin8p Verified chr2:101888-105223 101888-105223 99.0% 69.96 74.81 58.76 54.82 58.15 42.10 72.39 56.79 50.13 0.27 0.23 0.21 -0.18 -0.20 Matched[138]
YBL062W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr2:105310-105690 105310-105690 99.4% 422.30 411.75 417.02 332.56 353.68 248.10 417.02 374.79 300.89 1.54 1.52 1.25 -0.32 -0.35 Covered/w/another[139]
YBL061C SKT5 "Activator of Chs3p (chitin synthase III), recruits Chs3p to the bud neck via interaction with Bni4p; has similarity to Shc1p, which activates Chs3p during sporulation" Verified chr2:105318-107408 105318-107408 99.2% 263.24 256.49 228.04 211.17 174.05 178.38 259.86 219.61 176.22 0.96 0.89 0.73 -0.32 -0.23 Matched[139]
YBL060W YEL1 Guanine nucleotide exchange factor specific for Arf3p; localized to the bud neck and tip; required for localization of Arf3p to the bud neck and tip Uncharacterized chr2:107934-109997 107934-109997 98.7% 66.25 70.17 64.78 44.66 61.83 31.41 68.21 54.72 46.62 0.25 0.22 0.19 -0.23 0.15 Matched[140]
YBL059C-A Putative protein of unknown function; contains twin Cx9C motifs that can form coiled coil-helix-coiled-coil helix fold; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus Uncharacterized chr2:110127-110541 110127-110422,110508-110541 99.3% 332.49 271.48 305.03 219.62 549.06 289.78 301.98 262.33 419.42 1.11 1.06 1.74 0.68 0.24 Matched[141]
YBL059W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr2:110596-111246 110596-110881,110951-111246 98.5% 62.77 74.97 76.72 52.31 99.38 27.90 68.87 64.51 63.64 0.25 0.26 0.26 -0.02 -0.15 Matched[142]
YBL058W SHP1 UBX (ubiquitin regulatory X) domain-containing protein that regulates Glc7p phosphatase activity and interacts with Cdc48p; interacts with ubiquitylated proteins in vivo and is required for degradation of a ubiquitylated model substrate Verified chr2:111439-112710 111439-112710 98.3% 423.21 421.61 527.22 480.02 796.03 715.22 422.41 503.62 755.63 1.56 2.04 3.13 0.59 0.93 Matched[143]
YBL057C PTH2 One of two (see also PTH1) mitochondrially-localized peptidyl-tRNA hydrolases; negatively regulates the ubiquitin-proteasome pathway via interactions with ubiquitin-like ubiquitin-associated proteins; dispensable for cell growth Verified chr2:112803-113447 112803-113447 99.1% 267.48 231.51 237.76 181.45 312.85 176.76 249.49 209.61 244.80 0.92 0.85 1.01 0.22 0.15 Matched[144]
YBL056W PTC3 Type 2C protein phosphatase; dephosphorylates Hog1p (see also Ptc2p) to limit maximal kinase activity induced by osmotic stress; dephosphorylates T169 phosphorylated Cdc28p (see also Ptc2p); role in DNA checkpoint inactivation Verified chr2:113765-115171 113765-115171 98.7% 959.11 991.51 910.86 904.38 1071.43 707.81 975.31 907.62 889.62 3.60 3.68 3.69 -0.03 -0.06 Matched[145]
YBL055C 3'-->5' exonuclease and endonuclease with a possible role in apoptosis; has similarity to mammalian and C. elegans apoptotic nucleases Verified chr2:115576-116832 115576-116832 99.1% 138.01 123.57 97.89 85.85 48.95 33.70 130.79 91.87 41.32 0.48 0.37 0.17 -1.15 -0.75 Matched[146]
YBL054W Protein of unknown function involved in rRNA and ribosome biosynthesis Uncharacterized chr2:117592-119169 117592-119169 98.8% 85.98 42.35 23.74 15.40 10.27 3.85 64.16 19.57 7.06 0.24 0.08 0.03 -1.47 -1.27 Frag<80[147]
YBL053W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr2:119338-119712 119338-119712 99.7% 318.15 248.64 307.45 245.96 165.76 64.16 283.39 276.71 114.96 1.05 1.12 0.48 -1.27 -0.60 Covered/w/another[148]
YBL052C SAS3 "Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; sas3 gcn5 double mutation confers lethality" Verified chr2:119382-121877 119382-121877 99.4% 227.43 178.23 189.53 171.38 88.71 57.26 202.83 180.45 72.99 0.75 0.73 0.30 -1.31 -1.25 Matched[148]
YBL051C PIN4 "Protein involved in G2/M phase progression and response to DNA damage, interacts with Rad53p; contains an RNA recognition motif, a nuclear localization signal, and several SQ/TQ cluster domains; hyperphosphorylated in response to DNA damage" Verified chr2:122756-124762 122756-124762 98.8% 962.68 972.26 817.95 887.04 511.85 585.48 967.47 852.50 548.66 3.57 3.46 2.27 -0.64 -0.00 Matched[150]
YBL050W SEC17 "Peripheral membrane protein required for vesicular transport between ER and Golgi and for the 'priming' step in homotypic vacuole fusion, part of the cis-SNARE complex; has similarity to alpha-SNAP" Verified chr2:125128-126122 125128-125157,125274-126122 98.5% 474.69 495.48 518.58 490.86 786.53 579.79 485.08 504.72 683.16 1.79 2.05 2.83 0.44 0.52 Matched[151]
YBL049W MOH1 "Protein of unknown function, has homology to kinase Snf7p; not required for growth on nonfermentable carbon sources; essential for viability in stationary phase" Verified chr2:126831-127247 126831-127247 98.8% 67.97 128.67 46.13 70.40 121.38 104.39 98.32 58.26 112.89 0.36 0.24 0.47 0.95 1.62 Matched[152]
YBL048W "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data" Dubious chr2:127302-127613 127302-127613 99.5% 67.62 74.06 48.30 54.74 103.05 80.50 70.84 51.52 91.78 0.26 0.21 0.38 0.83 0.86 Covered/w/another[152]
YBL047C EDE1 "Key endocytic protein involved in a network of interactions with other endocytic proteins, binds membranes in a ubiquitin-dependent manner, may also bind ubiquitinated membrane-associated proteins" Verified chr2:127898-132043 127898-132043 98.9% 306.02 362.10 350.40 356.74 255.79 385.02 334.06 353.57 320.40 1.23 1.44 1.33 -0.14 0.77 Frag>80[153,154]
YBL046W PSY4 Putative regulatory subunit of an evolutionarily conserved protein phosphatase complex containing the catalytic subunit Pph3p and a third subunit Psy2p; required for cisplatin resistance; GFP-fusion protein localizes to the nucleus Verified chr2:132427-133752 132427-133752 98.2% 117.50 76.03 91.39 96.77 109.82 108.29 96.77 94.08 109.06 0.36 0.38 0.45 0.21 0.55 Matched[155]
YBL045C COR1 "Core subunit of the ubiquinol-cytochrome c reductase complex (bc1 complex), which is a component of the mitochondrial inner membrane electron transport chain" Verified chr2:134146-135519 134146-135519 98.8% 939.57 969.79 1018.42 1302.87 1463.52 1551.22 954.68 1160.65 1507.37 3.52 4.71 6.25 0.38 0.61 Matched[156]
YBL044W Putative protein of unknown function; YBL044W is not an essential protein Uncharacterized chr2:136001-136369 136001-136369 98.2% 5.52 2.76 0.00 5.52 5.52 16.56 4.14 2.76 11.04 0.02 0.01 0.05 2.00 -0.37
YBL043W ECM13 Non-essential protein of unknown function Verified chr2:136691-137464 136691-137464 98.5% 6.56 20.98 5.24 9.18 7.87 11.80 13.77 7.21 9.83 0.05 0.03 0.04 0.45 -0.21
YBL042C FUI1 "High affinity uridine permease, localized to the plasma membrane; not involved in uracil transport" Verified chr2:138344-140263 138344-140263 98.8% 356.75 491.12 317.75 319.33 41.63 27.40 423.93 318.54 34.52 1.56 1.29 0.14 -3.21 -3.35 Frag>80[157,158]
YBL041W PRE7 20S proteasome beta-type subunit Verified chr2:141250-141975 141250-141975 98.6% 835.63 871.97 887.34 730.83 1551.09 994.93 853.80 809.08 1273.01 3.15 3.28 5.27 0.65 0.56 Matched[160]
YBL040C ERD2 "HDEL receptor, an integral membrane protein that binds to the HDEL motif in proteins destined for retention in the endoplasmic reticulum; has a role in maintenance of normal levels of ER-resident proteins" Verified chr2:142115-142871 142115-142752,142850-142871 99.0% 682.30 544.62 582.87 501.78 1252.93 616.52 613.46 542.33 934.73 2.26 2.20 3.87 0.79 -0.24 Frag>80[161]
YBL039W-B Putative protein of unknown function Uncharacterized chr2:143396-143575 143396-143575 99.1% 173.87 145.83 201.92 179.48 431.88 252.40 159.85 190.70 342.14 0.59 0.77 1.42 0.84 NaN Covered/w/another[162]
YBL039C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified ORF URA7; identified by expression profiling and mass spectrometry" Dubious chr2:144951-145034 144951-145034 98.9% 433.52 192.67 264.93 168.59 12.04 36.13 313.10 216.76 24.08 1.16 0.88 0.10 -3.17 NaN Covered/w/another[162]
YBL039C URA7 "Major CTP synthase isozyme (see also URA8), catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis" Verified chr2:143992-145731 143992-145731 99.1% 521.17 227.25 301.46 249.86 22.03 6.38 374.21 275.66 14.20 1.38 1.12 0.06 -4.28 -3.91 Covered/w/another[162]
YBL038W MRPL16 Mitochondrial ribosomal protein of the large subunit Verified chr2:146190-146888 146190-146888 98.4% 308.16 334.32 356.13 364.85 421.54 266.00 321.24 360.49 343.77 1.19 1.46 1.42 -0.07 -0.21 Covered/w/another[162]
YBL037W APL3 "Alpha-adaptin, large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport" Verified chr2:147212-150289 147212-150289 99.0% 88.27 83.02 78.75 74.48 62.67 46.59 85.64 76.62 54.63 0.32 0.31 0.23 -0.49 -0.50 Matched[163]
YBL036C "Single-domain racemase, possibly non-specific due to the lack of the second domain, which presumably determines specificity; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS" Verified chr2:150450-151223 150450-151223 99.4% 419.98 354.97 365.37 297.76 399.18 274.35 387.47 331.56 336.76 1.43 1.35 1.40 0.02 -0.29 Matched[164]
YBL035C POL12 "B subunit of DNA polymerase alpha-primase complex, required for initiation of DNA replication during mitotic and premeiotic DNA synthesis; also functions in telomere capping and length regulation" Verified chr2:151496-153613 151496-153613 98.9% 118.37 94.98 91.17 75.41 20.05 11.46 106.68 83.29 15.75 0.39 0.34 0.07 -2.40 -1.53 Matched[165]
YBL034C STU1 Component of the mitotic spindle that binds to interpolar microtubules via its association with beta-tubulin (Tub2p); required for interpolar microtubules to provide an outward force on the spindle poles Verified chr2:153851-158392 153851-158392 99.1% 45.75 45.08 42.64 42.42 27.54 34.42 45.42 42.53 30.98 0.17 0.17 0.13 -0.46 0.14 Frag>80[166,167]
YBL033C RIB1 GTP cyclohydrolase II; catalyzes the first step of the riboflavin biosynthesis pathway Verified chr2:158659-159696 158659-159696 98.9% 158.81 196.81 174.40 177.32 238.70 181.22 177.81 175.86 209.96 0.66 0.71 0.87 0.26 0.60 Frag>80[167,168]
YBL032W HEK2 RNA binding protein with similarity to hnRNP-K that localizes to the cytoplasm and to subtelomeric DNA; required for the proper localization of ASH1 mRNA; involved in the regulation of telomere position effect and telomere length Verified chr2:160187-161332 160187-161332 98.4% 595.77 533.71 604.63 539.03 376.79 275.72 564.74 571.83 326.25 2.08 2.32 1.35 -0.81 -0.74 Matched[169]
YBL031W SHE1 Cytoskeletal protein of unknown function; overexpression causes growth arrest Verified chr2:161702-162718 161702-162718 98.9% 108.39 99.44 73.59 81.54 80.55 50.71 103.92 77.56 65.63 0.38 0.31 0.27 -0.24 -0.06 Matched[170]
YBL030C PET9 "Major ADP/ATP carrier of the mitochondrial inner membrane, exchanges cytosolic ADP for mitochondrially synthesized ATP; phosphorylated; required for viability in many common lab strains carrying a mutation in the polymorphic SAL1 gene" Verified chr2:163044-164000 163044-164000 98.7% 1967.46 1760.02 2417.25 2823.65 2525.20 1973.81 1863.74 2620.45 2249.50 6.88 10.64 9.32 -0.22 -0.95 Matched[172]
YBL029C-A Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; has potential orthologs in Saccharomyces species and in Yarrowia lipolytica Uncharacterized chr2:164491-164775 164491-164775 98.8% 234.35 209.50 344.43 284.07 766.98 390.59 221.93 314.25 578.78 0.82 1.28 2.40 0.88 0.66 Matched[174]
YBL029W Non-essential protein of unknown function Uncharacterized chr2:166137-167267 166137-167267 97.4% 149.85 168.02 129.87 108.08 79.01 67.21 158.93 118.97 73.11 0.59 0.48 0.30 -0.70 -1.04 Matched[176]
YBL028C Protein of unknown function that may interact with ribosomes; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; predicted to be involved in ribosome biogenesis Verified chr2:167521-167841 167521-167841 99.6% 581.93 240.91 287.84 334.77 28.16 18.77 411.42 311.30 23.46 1.52 1.26 0.10 -3.73 -4.38 Covered/w/another[176]
YBL027W RPL19B "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl19Ap and has similarity to rat L19 ribosomal protein; rpl19a and rpl19b single null mutations result in slow growth, while the double null mutation is lethal" Verified chr2:168426-169379 168426-168427,168812-169379 65.8% 8229.33 6933.33 7453.33 6074.67 1168.00 1061.33 7581.33 6764.00 1114.67 27.99 27.46 4.62 -2.60 -3.50 Matched[177]
YBL026W LSM2 "Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA" Verified chr2:170626-171041 170626-170679,170808-171041 98.7% 707.44 608.89 591.29 612.41 471.62 232.29 658.16 601.85 351.96 2.43 2.44 1.46 -0.77 -1.36 Frag>80[179,180]
YBL025W RRN10 "Protein involved in promoting high level transcription of rDNA, subunit of UAF (upstream activation factor) for RNA polymerase I" Verified chr2:171484-171921 171484-171921 98.4% 120.64 85.84 85.84 83.52 69.60 44.08 103.24 84.68 56.84 0.38 0.34 0.24 -0.58 -0.19 Covered/w/another[181]
YBL024W NCL1 "S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase, methylates cytosine to m5C at several positions in tRNAs and intron-containing pre-tRNAs; similar to Nop2p and human proliferation associated nucleolar protein p120" Verified chr2:172537-174591 172537-174591 98.7% 481.03 315.43 379.00 316.90 85.26 42.88 398.23 347.95 64.07 1.47 1.41 0.27 -2.44 -2.23 Covered/w/another[181]
YBL023C MCM2 Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex Verified chr2:174923-177529 174923-177529 99.1% 90.61 81.70 78.60 73.96 69.70 65.05 86.15 76.28 67.37 0.32 0.31 0.28 -0.18 0.25 Matched[182]
YBL022C PIM1 "ATP-dependent Lon protease, involved in degradation of misfolded proteins in mitochondria; required for biogenesis and maintenance of mitochondria" Verified chr2:177877-181278 177877-181278 99.1% 259.82 211.47 248.84 225.71 277.61 297.19 235.65 237.28 287.40 0.87 0.96 1.19 0.28 0.98 Matched[183]
YBL021C HAP3 "Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; contains sequences contributing to both complex assembly and DNA binding" Verified chr2:181663-182097 181663-182097 99.1% 120.67 88.18 118.35 85.86 113.71 64.98 104.43 102.11 89.34 0.39 0.41 0.37 -0.19 -0.48 Covered/w/another[184]
YBL020W RFT1 "Flippase, essential integral membrane protein that is required for translocation of Man5GlcNac2-PP-Dol from the cytoplasmic side to the lumenal side of the ER membrane; mutation is suppressed by expression human p53 protein" Verified chr2:182404-184128 182404-184128 99.1% 142.22 127.00 112.96 117.05 62.04 45.65 134.61 115.00 53.84 0.50 0.47 0.22 -1.09 -0.81 Covered/w/another[184]
YBL019W APN2 Class II abasic (AP) endonuclease involved in repair of DNA damage; homolog of human HAP1 and E. coli exoIII Verified chr2:184356-185918 184356-185918 98.7% 49.91 83.62 53.16 48.62 110.20 84.92 66.77 50.89 97.56 0.25 0.21 0.40 0.94 0.43 Covered/w/another[184]
YBL018C POP8 "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends" Verified chr2:186001-186477 186001-186355,186431-186477 99.3% 195.49 125.31 162.91 140.35 82.71 7.52 160.40 151.63 45.11 0.59 0.62 0.19 -1.75 -1.97 Covered/w/another[184]
YBL017C PEP1 Type I transmembrane sorting receptor for multiple vacuolar hydrolases; cycles between the late-Golgi and prevacuolar endosome-like compartments Verified chr2:186847-191586 186847-191586 95.9% 257.05 313.83 257.05 239.67 114.22 147.45 285.44 248.36 130.84 1.05 1.01 0.54 -0.92 0.01 Frag<80[185]
YBL016W FUS3 "Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivatd by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its degradation" Verified chr2:192454-193515 192454-193515 98.6% 363.71 378.98 351.30 290.20 103.10 65.87 371.35 320.75 84.48 1.37 1.30 0.35 -1.92 -1.50 Matched[187]
YBL015W ACH1 "Acetyl-coA hydrolase, primarily localized to mitochondria; phosphorylated; required for acetate utilization and for diploid pseudohyphal growth" Verified chr2:194125-195705 194125-195705 98.5% 115.61 153.50 145.15 177.91 581.25 454.72 134.55 161.53 517.98 0.50 0.66 2.15 1.68 1.79 Matched[188]
YBL014C RRN6 "Protein involved in the transcription of 35S rRNA genes by RNA polymerase I; component of the core factor (CF) complex also composed of Rrn11p, Rrn7p and TATA-binding protein" Verified chr2:199067-201751 199067-201751 99.1% 87.93 62.00 54.86 56.74 46.97 34.57 74.97 55.80 40.77 0.28 0.23 0.17 -0.45 -0.26 Matched[190]
YBL013W FMT1 "Methionyl-tRNA formyltransferase, catalyzes the formylation of initiator Met-tRNA in mitochondria; potential Cdc28p substrate" Verified chr2:202059-203264 202059-203264 98.4% 16.85 21.06 15.16 22.74 14.32 24.43 18.95 18.95 19.37 0.07 0.08 0.08 0.03 1.12 Overlap[191]
YBL011W SCT1 "Glycerol 3-phosphate/dihydroxyacetone phosphate dual substrate-specific sn-1 acyltransferase of the glycerolipid biosynthesis pathway, prefers 16-carbon fatty acids, similar to Gpt2p, gene is constitutively transcribed" Verified chr2:203541-205820 203541-205820 98.1% 226.33 250.48 220.07 199.49 242.88 258.98 238.41 209.78 250.93 0.88 0.85 1.04 0.26 0.43 Matched[191]
YBL012C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr2:203409-203810 203409-203810 98.6% 98.41 141.31 113.55 111.03 93.37 143.83 119.86 112.29 118.60 0.44 0.46 0.49 0.08 0.08 Covered/w/another[191]
YBL010C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein colocalizes with clathrin-coated vesicles Uncharacterized chr2:206110-206952 206110-206952 99.3% 133.74 102.70 91.95 94.34 75.23 76.43 118.22 93.14 75.83 0.44 0.38 0.31 -0.30 -0.16 Matched[192]
YBL009W ALK2 Protein kinase; accumulation and phosphorylation are periodic during the cell cycle; phosphorylated in response to DNA damage; contains characteristic motifs for degradation via the APC pathway; similar to Alk1p and to mammalian haspins Verified chr2:207197-209227 207197-209227 99.0% 115.93 99.01 102.99 83.09 27.86 16.92 107.47 93.04 22.39 0.40 0.38 0.09 -2.06 -1.23 Matched[193]
YBL008W-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr2:209412-209651 209412-209651 99.1% 8.40 4.20 4.20 4.20 8.40 8.40 6.30 4.20 8.40 0.02 0.02 0.03 1.00 NaN Overlap[194]
YBL008W HIR1 "Non-essential transcriptional corepressor involved in the cell cycle-regulated transcription of histone H2A, H2B, H3 and H4 genes; contributes to nucleosome formation, heterochromatic gene silencing, and formation of functional kinetochores" Verified chr2:209656-212178 209656-212178 98.7% 54.61 46.58 48.18 34.13 38.95 22.89 50.59 41.16 30.92 0.19 0.17 0.13 -0.41 0.04 Matched[194]
YBL007C SLA1 Cytoskeletal protein binding protein required for assembly of the cortical actin cytoskeleton; interacts with proteins regulating actin dynamics and proteins required for endocytosis; found in the nucleus and cell cortex; has 3 SH3 domains Verified chr2:212635-216369 212635-216369 98.8% 267.19 305.40 288.87 278.03 301.33 400.24 286.29 283.45 350.79 1.06 1.15 1.45 0.31 0.95 Matched[195]
YBL006W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene LDB7/YBL006C" Dubious chr2:216714-216863 216714-216863 98.2% 468.46 420.93 475.25 325.88 699.29 305.52 444.70 400.57 502.40 1.64 1.63 2.08 0.33 NaN Covered/w/another[195]
YBL006C LDB7 "Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Npl6p, and Htl1p to form a module important for a broad range of RSC functions" Verified chr2:216590-217132 216590-217132 98.7% 387.94 371.15 410.32 287.22 546.47 268.57 379.55 348.77 407.52 1.40 1.42 1.69 0.22 -0.18 Covered/w/another[195]
YBL005W PDR3 "Transcriptional activator of the pleiotropic drug resistance network, regulates expression of ATP-binding cassette (ABC) transporters through binding to cis-acting sites known as PDREs (PDR responsive elements)" Verified chr2:217473-220403 217473-220403 99.1% 110.87 133.93 85.39 67.14 71.62 67.83 122.40 76.26 69.72 0.45 0.31 0.29 -0.13 0.29 Matched[196]
YBL004W UTP20 "Component of the small-subunit (SSU) processome, which is involved in the biogenesis of the 18S rRNA" Verified chr2:227639-235120 227639-235120 99.0% 103.45 43.22 52.80 37.68 6.62 3.11 73.33 45.24 4.86 0.27 0.18 0.02 -3.22 -2.79 Frag<80[199,200]
YBL003C HTA2 One of two nearly identical (see also HTA1) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p Verified chr2:235397-235795 235397-235795 70.9% 6596.20 5197.11 5882.53 4910.94 4663.62 2564.99 5896.66 5396.73 3614.31 21.77 21.91 14.98 -0.58 -1.27 Matched[201]
YBL002W HTB2 "One of two nearly identical (see HTB1) histone H2B subtypes required for chromatin assembly and chromosome function; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation" Verified chr2:236495-236890 236495-236890 84.8% 3283.96 2971.34 2792.71 2131.75 2998.14 1932.27 3127.65 2462.23 2465.20 11.55 9.99 10.21 0.00 -0.19 Matched[203]
YBL001C ECM15 "Non-essential protein of unknown function, likely exists as tetramer, may be regulated by the binding of small-molecule ligands (possibly sulfate ions), may have a role in yeast cell-wall biogenesis" Verified chr2:237155-237469 237155-237469 99.3% 1007.33 1403.86 1068.09 1122.45 3309.79 1848.37 1205.60 1095.27 2579.08 4.45 4.45 10.69 1.24 0.30 Matched[203]
YBR001C NTH2 "Putative neutral trehalase, required for thermotolerance and may mediate resistance to other cellular stresses" Verified chr2:238943-241285 238943-241285 98.9% 106.13 120.37 154.88 138.49 422.37 364.99 113.25 146.69 393.68 0.42 0.60 1.63 1.42 1.31 Matched[205]
YBR002C RER2 Cis-prenyltransferase involved in dolichol synthesis; participates in endoplasmic reticulum (ER) protein sorting Verified chr2:241710-242570 241710-242570 99.1% 199.15 209.69 178.06 124.18 164.01 97.23 204.42 151.12 130.62 0.75 0.61 0.54 -0.21 -0.14 Covered/w/another[206]
YBR003W COQ1 "Hexaprenyl pyrophosphate synthetase, catalyzes the first step in ubiquinone (coenzyme Q) biosynthesis" Verified chr2:242811-244232 242811-244232 98.9% 206.28 280.97 259.63 263.19 445.29 342.86 243.63 261.41 394.07 0.90 1.06 1.63 0.59 0.57 Covered/w/another[206]
YBR004C GPI18 "Functional ortholog of human PIG-V, which is a mannosyltransferase that transfers the second mannose in glycosylphosphatidylinositol biosynthesis; the authentic, non-tagged protein was localized to mitochondria" Verified chr2:244368-245669 244368-245669 99.0% 107.08 96.22 107.86 79.92 65.96 38.80 101.65 93.89 52.38 0.38 0.38 0.22 -0.84 -0.41 Matched[207]
YBR005W RCR1 "Protein of the ER membrane involved in cell wall chitin deposition; may function in the endosomal-vacuolar trafficking pathway, helping determine whether plasma membrane proteins are degraded or routed to the plasma membrane" Verified chr2:245908-246549 245908-246549 98.4% 68.06 96.54 75.97 117.12 156.69 132.95 82.30 96.54 144.82 0.30 0.39 0.60 0.58 1.04 Frag>80[208,209]
YBR006W UGA2 Succinate semialdehyde dehydrogenase involved in the utilization of gamma-aminobutyrate (GABA) as a nitrogen source; part of the 4-aminobutyrate and glutamate degradation pathways; localized to the cytoplasm Verified chr2:247012-248505 247012-248505 98.7% 77.30 112.56 100.36 93.58 339.04 225.80 94.93 96.97 282.42 0.35 0.39 1.17 1.54 1.45 Matched[210]
YBR007C DSF2 Deletion suppressor of mpt5 mutation Uncharacterized chr2:248807-251017 248807-251017 99.0% 116.08 148.99 77.69 79.06 77.69 71.75 132.53 78.38 74.72 0.49 0.32 0.31 -0.07 0.51 Matched[211]
YBR008C FLR1 "Plasma membrane multidrug transporter of the major facilitator superfamily, involved in efflux of fluconazole, diazaborine, benomyl, methotrexate, and other drugs" Verified chr2:252564-254210 252564-254210 98.8% 112.52 147.56 69.48 71.32 72.55 46.11 130.04 70.40 59.33 0.48 0.29 0.25 -0.25 -0.14 Covered[213]
YBR009C HHF1 One of two identical histone H4 proteins (see also HHF2); core histone required for chromatin assembly and chromosome function; contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity Verified chr2:255371-255682 255371-255682 33.0% 4351.27 3603.40 4157.02 3001.21 4225.01 2467.02 3977.34 3579.12 3346.01 14.68 14.53 13.86 -0.10 -1.39 Matched[214]
YBR010W HHT1 "One of two identical histone H3 proteins (see also HHT2); core histone required for chromatin assembly, involved in heterochromatin-mediated telomeric and HM silencing; regulated by acetylation, methylation, and mitotic phosphorylation" Verified chr2:256329-256739 256329-256739 62.6% 6026.23 5389.02 5505.59 4238.95 5831.96 3733.85 5707.62 4872.27 4782.90 21.07 19.78 19.82 -0.03 -0.61 Matched[216]
YBR011C IPP1 "Cytoplasmic inorganic pyrophosphatase (PPase), catalyzes the rapid exchange of oxygens from Pi with water, highly expressed and essential for viability, active-site residues show identity to those from E. coli PPase" Verified chr2:257110-257973 257110-257973 98.8% 3286.04 3382.06 3151.36 3185.32 3085.78 2742.66 3334.05 3168.34 2914.22 12.31 12.86 12.07 -0.12 -0.77 Matched[217]
YBR012C "Dubious open reading frame, unlikely to encode a functional protein; expression induced by iron-regulated transcriptional activator Aft2p" Dubious chr2:259145-259564 259145-259564 99.7% 43.00 191.12 38.22 45.39 23.89 28.67 117.06 41.81 26.28 0.43 0.17 0.11 -0.67 -0.06 Matched[218]
YBR013C "Putative protein of unknown function, haploid deletion mutant exhibits synthetic phenotype with alpha-synuclein" Uncharacterized chr2:265490-265879 265490-265879 99.2% 116.27 142.10 98.18 90.43 284.21 193.78 129.19 94.31 238.99 0.48 0.38 0.99 1.34 0.90 Frag>80[220,221]
YBR014C Putative thiol oxidoreductase; contains glutaredoxin domain; membrane localized Uncharacterized chr2:266725-267336 266725-267336 99.1% 352.67 344.43 405.41 309.83 789.40 509.24 348.55 357.62 649.32 1.29 1.45 2.69 0.86 0.85 Frag>80[222,223]
YBR015C MNN2 "Alpha-1,2-mannosyltransferase, responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment" Verified chr2:267710-269503 267710-269503 99.0% 356.44 384.03 371.08 341.80 241.57 215.66 370.23 356.44 228.61 1.37 1.45 0.95 -0.64 -0.14 Matched[224]
YBR016W "Plasma membrane protein of unknown function; has similarity to hydrophilins, which are hydrophilic, glycine-rich proteins involved in the adaptive response to hyperosmotic conditions" Uncharacterized chr2:270247-270633 270247-270633 97.8% 594.45 615.59 554.82 475.56 850.73 533.69 605.02 515.19 692.21 2.23 2.09 2.87 0.43 -0.08 Matched[226]
YBR017C KAP104 "Transportin, cytosolic karyopherin beta 2 involved in delivery of heterogeneous nuclear ribonucleoproteins to the nucleoplasm, binds rg-nuclear localization signals on Nab2p and Hrp1p, plays a role in cell-cycle progression" Verified chr2:270947-273703 270947-273703 98.9% 253.66 230.20 214.44 229.47 151.76 174.12 241.93 221.95 162.94 0.89 0.90 0.68 -0.45 0.36 Frag>80[226,227]
YBR018C GAL7 "Galactose-1-phosphate uridyl transferase, synthesizes glucose-1-phosphate and UDP-galactose from UDP-D-glucose and alpha-D-galactose-1-phosphate in the second step of galactose catabolism" Verified chr2:274427-275527 274427-275527 99.0% 16.52 22.94 18.35 12.85 57.81 39.46 19.73 15.60 48.64 0.07 0.06 0.20 1.64 1.85 Matched[228]
YBR019C GAL10 "UDP-glucose-4-epimerase, catalyzes the interconversion of UDP-galactose and UDP-D-glucose in galactose metabolism; also catalyzes the conversion of alpha-D-glucose or alpha-D-galactose to their beta-anomers" Verified chr2:276253-278352 276253-278352 99.2% 20.64 24.00 20.16 17.28 47.04 52.81 22.32 18.72 49.92 0.08 0.08 0.21 1.42 1.15 Frag<80[229]
YBR020W GAL1 "Galactokinase, phosphorylates alpha-D-galactose to alpha-D-galactose-1-phosphate in the first step of galactose catabolism; expression regulated by Gal4p" Verified chr2:279021-280607 279021-280607 98.8% 50.39 49.75 31.25 27.43 15.95 12.76 50.07 29.34 14.35 0.18 0.12 0.06 -1.03 -0.08 Covered[230]
YBR021W FUR4 "Uracil permease, localized to the plasma membrane; expression is tightly regulated by uracil levels and environmental cues" Verified chr2:281443-283344 281443-283344 99.0% 79.67 64.27 81.26 70.64 18.06 11.68 71.97 75.95 14.87 0.27 0.31 0.06 -2.35 -1.94 Frag>80[231,232]
YBR022W POA1 "Phosphatase that is highly specific for ADP-ribose 1''-phosphate, a tRNA splicing metabolite; may have a role in regulation of tRNA splicing" Verified chr2:283738-284271 283738-284271 98.7% 189.74 176.46 159.38 130.92 394.66 208.71 183.10 145.15 301.68 0.68 0.59 1.25 1.06 0.42 Matched[233]
YBR023C CHS3 "Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for synthesis of the majority of cell wall chitin, the chitin ring during bud emergence, and spore wall chitosan" Verified chr2:284428-287925 284428-287925 99.0% 153.01 157.63 160.51 135.11 75.64 82.28 155.32 147.81 78.96 0.57 0.60 0.33 -0.90 -0.31 Frag>80[233,234]
YBR024W SCO2 "Protein anchored to the mitochondrial inner membrane, similar to Sco1p and may have a redundant function with Sco1p in delivery of copper to cytochrome c oxidase; interacts with Cox2p" Verified chr2:289445-290350 289445-290350 98.6% 236.32 403.19 244.16 269.91 515.19 391.99 319.75 257.03 453.59 1.18 1.04 1.88 0.82 0.58 Matched[235]
YBR025C OLA1 P-loop ATPase with similarity to human OLA1 and bacterial YchF; identified as specifically interacting with the proteasome; protein levels are induced by hydrogen peroxide Verified chr2:290681-291865 290681-291865 99.0% 2249.28 1949.38 1811.35 1722.74 2398.38 2189.64 2099.33 1767.05 2294.01 7.75 7.17 9.50 0.38 0.58 Frag>80[236,237,238]
YBR026C ETR1 "2-enoyl thioester reductase, member of the medium chain dehydrogenase/reductase family; localized to in mitochondria, where it has a probable role in fatty acid synthesis" Verified chr2:292877-294019 292877-294019 99.1% 376.12 444.10 394.66 409.67 1237.83 965.01 410.11 402.16 1101.42 1.51 1.63 4.56 1.45 1.73 Frag>80[239,240]
YBR027C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr2:294024-294356 294024-294356 99.0% 87.92 93.99 93.99 75.80 103.08 72.76 90.96 84.89 87.92 0.34 0.34 0.36 0.05 1.25 Covered[240]
YBR028C "Putative protein kinase, possible substrate of cAMP-dependent protein kinase (PKA)" Uncharacterized chr2:294425-296002 294425-296002 99.2% 245.32 287.49 230.63 212.74 100.94 94.55 266.40 221.68 97.75 0.98 0.90 0.40 -1.18 -0.50 Matched[241]
YBR029C CDS1 "Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); an enzyme that catalyzes that conversion of CTP + phosphate into diphosphate + CDP-diaclglyerol, a critical step in the synthesis of all major yeast phospholipids" Verified chr2:296369-297742 296369-297742 98.8% 299.83 234.27 325.62 293.20 204.06 211.43 267.05 309.41 207.75 0.99 1.26 0.86 -0.57 -0.12 Frag>80[242,243]
YBR030W Putative protein of unknown function; predicted protein contains a SET domain (S-adenosyl-L-methionine-binding fold) Uncharacterized chr2:298292-299950 298292-299950 98.7% 107.46 101.96 94.03 86.09 32.36 27.48 104.71 90.06 29.92 0.39 0.37 0.12 -1.59 -1.07 Matched[244]
YBR031W RPL4A "N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl4Bp and has similarity to E. coli L4 and rat L4 ribosomal proteins" Verified chr2:300166-301254 300166-301254 7.4% 5996.88 4285.27 4560.12 3510.67 1086.93 437.27 5141.07 4035.40 762.10 18.98 16.38 3.16 -2.40 -3.26 Frag<80[245,246,247]
YBR032W "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data" Dubious chr2:301519-301821 301519-301821 98.8% 23.37 6.68 20.03 13.36 50.08 36.73 15.03 16.69 43.41 0.06 0.07 0.18 1.38 -0.22 Covered/w/another[248]
YBR033W EDS1 Putative zinc cluster protein; YBR033W is not an essential gene Uncharacterized chr2:301944-304703 301944-304703 98.8% 21.27 22.00 22.37 20.54 53.91 43.28 21.64 21.45 48.59 0.08 0.09 0.20 1.18 0.55 Matched[248]
YBR034C HMT1 "Nuclear SAM-dependent mono- and asymmetric arginine dimethylating methyltransferase that modifies hnRNPs, including Npl3p and Hrp1p, thus facilitating nuclear export of these proteins; required for viability of npl3 mutants" Verified chr2:304930-305976 304930-305976 98.9% 506.94 324.44 393.00 265.54 55.04 26.07 415.69 329.27 40.56 1.53 1.34 0.17 -3.02 -2.50 Matched[249]
YBR035C PDX3 "Pyridoxine (pyridoxamine) phosphate oxidase, has homologs in E. coli and Myxococcus xanthus; transcription is under the general control of nitrogen metabolism" Verified chr2:306269-306955 306269-306955 99.0% 542.38 768.74 607.06 645.27 1086.23 754.04 655.56 626.16 920.14 2.42 2.54 3.81 0.56 0.48 Frag>80[250,251]
YBR036C CSG2 "Endoplasmic reticulum membrane protein, required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations" Verified chr2:309081-310313 309081-310313 98.6% 498.34 511.50 532.05 486.00 557.55 443.24 504.92 509.03 500.39 1.86 2.07 2.07 -0.02 0.25 Matched[254]
YBR037C SCO1 "Copper-binding protein of the mitochondrial inner membrane, required for cytochrome c oxidase activity and respiration; may function to deliver copper to cytochrome c oxidase; has similarity to thioredoxins" Verified chr2:310564-311451 310564-311451 98.9% 157.10 239.07 204.91 226.54 465.61 270.94 198.08 215.73 368.28 0.73 0.88 1.53 0.77 0.79 Frag>80[255,256]
YBR038W CHS2 "Chitin synthase II, requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for the synthesis of chitin in the primary septum during cytokinesis" Verified chr2:311897-314788 311897-314788 98.8% 154.97 153.57 169.31 145.53 138.18 181.56 154.27 157.42 159.87 0.57 0.64 0.66 0.02 0.68 Matched[257]
YBR039W ATP3 "Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis" Verified chr2:315575-316510 315575-316510 98.9% 907.74 893.69 962.85 1230.85 1121.71 935.84 900.72 1096.85 1028.77 3.32 4.45 4.26 -0.09 -0.45 Matched[258]
YBR040W FIG1 "Integral membrane protein required for efficient mating; may participate in or regulate the low affinity Ca2+ influx system, which affects intracellular signaling and cell-cell fusion during mating" Verified chr2:316968-317864 316968-317864 99.2% 14.61 6.74 11.24 11.24 3.37 7.87 10.67 11.24 5.62 0.04 0.05 0.02 -1.00 -2.61 Frag<80[259]
YBR041W FAT1 "Fatty acid transporter and very long-chain fatty acyl-CoA synthetase, may form a complex with Faa1p or Faa4p that imports and activates exogenous fatty acids" Verified chr2:318266-320275 318266-320275 98.9% 287.12 302.71 320.81 297.18 226.78 122.69 294.92 308.99 174.74 1.09 1.25 0.72 -0.82 -0.94 Matched[260]
YBR042C CST26 "Protein of unknown function, affects chromosome stability when overexpressed" Verified chr2:320416-321609 320416-321609 99.0% 196.23 248.67 182.70 171.70 164.09 98.96 222.45 177.20 131.52 0.82 0.72 0.54 -0.43 -0.69 Covered/w/another[261]
YBR043C QDR3 "Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, barban, cisplatin, and bleomycin" Verified chr2:321876-323945 321876-323945 99.0% 94.20 118.60 79.07 62.47 51.74 40.02 106.40 70.77 45.88 0.39 0.29 0.19 -0.63 -0.43 Covered/w/another[261]
YBR044C TCM62 Protein involved in the assembly of the mitochondrial succinate dehydrogenase complex; putative chaperone Verified chr2:324337-326058 324337-326058 99.2% 88.96 112.37 98.32 84.28 137.54 83.11 100.67 91.30 110.32 0.37 0.37 0.46 0.27 0.50 Matched[262]
YBR045C GIP1 "Meiosis-specific regulatory subunit of the Glc7p protein phosphatase, regulates spore wall formation and septin organization, required for expression of some late meiotic genes and for normal localization of Glc7p" Verified chr2:328369-330090 328369-330090 99.3% 15.79 22.81 15.79 17.55 59.07 30.41 19.30 16.67 44.74 0.07 0.07 0.19 1.42 1.65 Covered[263]
YBR046C ZTA1 "Zeta-crystallin homolog, found in the cytoplasm and nucleus; has similarity to E. coli quinone oxidoreductase and to human zeta-crystallin, which has quinone oxidoreductase activity" Verified chr2:330505-331509 330505-331509 99.1% 181.70 310.20 267.03 269.04 816.16 710.75 245.95 268.04 763.46 0.91 1.09 3.16 1.51 1.50 Matched[264]
YBR047W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr2:331831-332358 331831-332358 98.8% 61.31 116.88 30.66 49.82 137.95 61.31 89.09 40.24 99.63 0.33 0.16 0.41 1.31 1.08 Matched[265]
YBR048W RPS11B Protein component of the small (40S) ribosomal subunit; identical to Rps11Ap and has similarity to E. coli S17 and rat S11 ribosomal proteins Verified chr2:332829-333810 332829-332873,333385-333810 51.5% 5826.80 4977.32 5294.85 4944.33 1698.97 1583.51 5402.06 5119.59 1641.24 19.94 20.78 6.80 -1.64 -2.33 Matched[266]
YBR049C REB1 RNA polymerase I enhancer binding protein; DNA binding protein which binds to genes transcribed by both RNA polymerase I and RNA polymerase II; required for termination of RNA polymerase I transcription Verified chr2:334384-336816 334384-336816 99.3% 172.22 133.72 177.60 150.27 149.86 143.24 152.97 163.94 146.55 0.56 0.67 0.61 -0.16 0.50 Matched[268]
YBR051W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partiallly overlaps the REG2/YBR050C regulatory subunit of the Glc7p type-1 protein phosphatase" Dubious chr2:337986-338336 337986-338336 98.8% 20.19 69.21 60.56 69.21 5.77 11.54 44.70 64.89 8.65 0.17 0.26 0.04 -2.91 -0.04 Covered/w/another[269]
YBR050C REG2 "Regulatory subunit of the Glc7p type-1 protein phosphatase; involved with Reg1p, Glc7p, and Snf1p in regulation of glucose-repressible genes, also involved in glucose-induced proteolysis of maltose permease" Verified chr2:337181-338197 337181-338197 99.2% 32.71 68.40 82.28 87.23 31.72 11.90 50.56 84.75 21.81 0.19 0.34 0.09 -1.96 -1.85 Matched[269]
YBR052C RFS1 Protein of unknown function; member of a flavodoxin-like fold protein family that includes Pst2p and Ycp4p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern Verified chr2:338718-339350 338718-339350 99.1% 927.92 1321.73 1155.92 1151.13 3506.01 2672.16 1124.83 1153.52 3089.09 4.15 4.68 12.80 1.42 1.27 Frag>80[270,271,272]
YBR053C Putative protein of unknown function; induced by cell wall perturbation Uncharacterized chr2:339673-340749 339673-340749 99.1% 236.98 342.83 274.45 302.55 1055.66 739.05 289.91 288.50 897.35 1.07 1.17 3.72 1.64 1.57 Frag>80[272,273]
YBR054W YRO2 "Putative protein of unknown function; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies; transcriptionally regulated by Haa1p" Verified chr2:343099-344133 343099-344133 96.9% 191.35 854.12 128.57 158.47 2123.83 1645.45 522.74 143.52 1884.64 1.93 0.58 7.81 3.72 3.72 Matched[274]
YBR055C PRP6 "Splicing factor, component of the U4/U6-U5 snRNP complex" Verified chr2:344600-347299 344600-347299 99.3% 125.31 112.26 107.41 86.15 66.76 59.30 118.79 96.78 63.03 0.44 0.39 0.26 -0.62 0.15 Matched[275]
YBR056W Putative cytoplasmic protein of unknown function Uncharacterized chr2:347877-349382 347877-349382 98.7% 263.78 395.00 362.03 374.81 1250.27 837.10 329.39 368.42 1043.68 1.22 1.50 4.32 1.50 1.44 Matched[276]
YBR056W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YBR056C-B" Dubious chr2:351253-351453 351253-351453 98.9% 25.15 20.12 20.12 30.18 20.12 30.18 22.64 25.15 25.15 0.08 0.10 0.10 0.00 NaN Matched[279]
YBR056C-B "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; almost completely overlaps the dubious ORF YBR056W-A" Dubious chr2:351291-351449 351291-351449 98.7% 31.87 19.12 19.12 19.12 19.12 31.87 25.50 19.12 25.50 0.09 0.08 0.11 0.42 NaN Matched[279]
YBR057C MUM2 "Cytoplasmic protein essential for meiotic DNA replication and sporulation; interacts with Orc2p, which is a component of the origin recognition complex" Verified chr2:352191-353291 352191-353291 99.2% 211.51 247.22 239.90 174.89 207.85 142.84 229.37 207.39 175.35 0.85 0.84 0.73 -0.24 -0.03 Frag>80[280,281,282]
YBR058C UBP14 "Ubiquitin-specific protease that specifically disassembles unanchored ubiquitin chains; involved in fructose-1,6-bisphosphatase (Fbp1p) degradation; similar to human isopeptidase T" Verified chr2:353670-356015 353670-356015 99.1% 162.53 145.76 130.71 136.30 122.11 134.58 154.14 133.50 128.34 0.57 0.54 0.53 -0.06 0.39 Frag>80[282,283]
YBR058C-A TSC3 "Protein that stimulates the activity of serine palmitoyltransferase (Lcb1p, Lcb2p) several-fold; involved in sphingolipid biosynthesis" Verified chr2:356322-356564 356322-356564 98.9% 678.34 649.21 636.73 645.05 1144.44 611.76 663.78 640.89 878.10 2.45 2.60 3.64 0.45 -0.02 Matched[284]
YBR059C AKL1 "Ser-Thr protein kinase, member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization" Verified chr2:356859-360185 356859-360185 99.1% 159.57 199.31 188.08 192.03 235.41 295.47 179.44 190.05 265.44 0.66 0.77 1.10 0.48 1.02 Matched[285]
YBR060C ORC2 "Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; phosphorylated by Cdc28p" Verified chr2:360650-362512 360650-362512 99.1% 128.97 101.34 110.55 95.38 68.28 49.31 115.16 102.96 58.80 0.43 0.42 0.24 -0.81 -0.12 Matched[286]
YBR061C TRM7 "2'-O-ribose methyltransferase, methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop" Verified chr2:364785-365717 364785-365717 99.0% 150.43 122.29 120.13 115.80 30.30 23.81 136.36 117.97 27.06 0.50 0.48 0.11 -2.12 -1.79 Covered[287]
YBR062C Hypothetical protein Uncharacterized chr2:365974-366598 365974-366500,366583-366598 99.1% 222.89 261.90 182.03 217.32 774.55 404.92 242.40 199.67 589.74 0.89 0.81 2.44 1.56 1.12 Matched[288]
YBR064W Dubious open reading frame unlikely to encode a protein; partially overlaps the uncharacterized ORF YBR063C Dubious chr2:367761-368189 367761-368189 99.2% 89.32 108.12 63.46 44.66 119.87 105.77 98.72 54.06 112.82 0.36 0.22 0.47 1.06 0.13 Covered/w/another[289]
YBR063C Putative protein of unknown function; YBR063C is not an essential gene Uncharacterized chr2:366968-368182 366968-368182 99.2% 115.31 136.05 63.88 61.39 166.74 140.20 125.68 62.63 153.47 0.46 0.25 0.64 1.29 1.33 Covered/w/another[289]
YBR065C ECM2 "Pre-mRNA splicing factor, facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome, function may be regulated by Slu7p" Verified chr2:368582-369676 368582-369676 99.2% 67.22 81.96 43.28 47.89 111.43 131.69 74.59 45.58 121.56 0.28 0.19 0.50 1.42 1.87 Covered/w/another[289]
YBR066C NRG2 Transcriptional repressor that mediates glucose repression and negatively regulates filamentous growth; has similarity to Nrg1p Verified chr2:370035-370697 370035-370697 99.0% 138.62 280.29 170.61 149.29 396.06 319.90 209.46 159.95 357.98 0.77 0.65 1.48 1.16 0.52 Frag>80[290,291]
YBR067C TIP1 Major cell wall mannoprotein with possible lipase activity; transcription is induced by heat- and cold-shock; member of the Srp1p/Tip1p family of serine-alanine-rich proteins Verified chr2:372100-372732 372100-372732 93.8% 2139.25 10123.53 2159.46 2279.06 7034.25 6618.19 6131.39 2219.26 6826.22 22.63 9.01 28.28 1.62 1.64 Frag>80[293,294,295]
YBR068C BAP2 "High-affinity leucine permease, functions as a branched-chain amino acid permease involved in the uptake of leucine, isoleucine and valine; contains 12 predicted transmembrane domains" Verified chr2:373858-375687 373858-375687 98.9% 572.10 631.80 492.50 359.29 599.18 415.12 601.95 425.90 507.15 2.22 1.73 2.10 0.25 0.18 Matched[297]
YBR069C TAT1 "Amino acid transport protein for valine, leucine, isoleucine, and tyrosine, low-affinity tryptophan and histidine transporter; overexpression confers FK506 resistance" Verified chr2:376571-378430 376571-378430 98.8% 555.47 335.68 480.39 345.47 83.78 52.77 445.57 412.93 68.28 1.64 1.68 0.28 -2.60 -2.20 Matched[299]
YBR070C ALG14 Component of UDP-GlcNAc transferase required for the second step of dolichyl-linked oligosaccharide synthesis; anchors the catalytic subunit Alg13p to the ER membrane; similar to bacterial and human glycosyltransferases Verified chr2:379218-379931 379218-379931 99.1% 185.16 147.00 183.75 122.97 158.30 83.39 166.08 153.36 120.85 0.61 0.62 0.50 -0.34 -0.45 Frag>80[300,301]
YBR071W Putative protein of unknown function; (GFP)-fusion and epitope-tagged proteins localize to the cytoplasm; mRNA expression may be regulated by the cell cycle and/or cell wall stress Uncharacterized chr2:380408-381043 380408-381043 98.6% 240.85 237.66 237.66 205.76 309.43 178.64 239.25 221.71 244.04 0.88 0.90 1.01 0.14 0.03 Matched[302]
YBR072W HSP26 "Small heat shock protein (sHSP) with chaperone activity; forms hollow, sphere-shaped oligomers that suppress unfolded proteins aggregation; oligomer activation requires a heat-induced conformational change; not expressed in unstressed cells" Verified chr2:382027-382671 382027-382671 98.6% 207.62 1612.16 234.35 272.10 62613.28 37834.72 909.89 253.23 50224.00 3.36 1.03 208.10 7.63 5.26 Matched[304]
YBR072C-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr2:382855-383016 382855-383016 98.8% 31.25 18.75 6.25 18.75 18.75 43.75 25.00 12.50 31.25 0.09 0.05 0.13 1.32 NaN Covered/w/another[304]
YBR073W RDH54 "DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in recombinational repair of DNA double-strand breaks during mitosis and meiosis; proposed to be involved in crossover interference" Verified chr2:383209-385983 383209-385983 98.8% 229.04 197.31 180.90 169.59 56.89 49.24 213.17 175.24 53.07 0.79 0.71 0.22 -1.72 -1.47 Matched[305]
YBR074W Putative metalloprotease Uncharacterized chr2:386281-389211 386281-389211 98.9% 180.02 162.09 153.12 140.02 91.39 78.63 171.05 146.57 85.01 0.63 0.59 0.35 -0.79 -0.06 Matched[306]
YBR076W ECM8 Non-essential protein of unknown function Verified chr2:390369-391388 390369-391388 99.0% 8.91 22.78 21.79 17.83 43.58 30.70 15.85 19.81 37.14 0.06 0.08 0.15 0.91 1.84 Frag>80[307,308]
YBR076C-A Dubious open reading frame unlikely to encode a protein; partially overlaps verified gene ECM8; identified by fungal homology and RT-PCR Dubious chr2:391345-391611 391345-391611 98.2% 110.58 137.27 163.97 91.52 186.84 114.39 123.93 127.74 150.62 0.46 0.52 0.62 0.24 NaN Matched[308]
YBR077C SLM4 "Component of the EGO complex, which is involved in the regulation of microautophagy, and of the GSE complex, which is required for proper sorting of amino acid permease Gap1p; gene exhibits synthetic genetic interaction with MSS4" Verified chr2:391799-392287 391799-392287 99.3% 222.53 245.19 271.98 247.25 358.52 255.49 233.86 259.62 307.01 0.86 1.05 1.27 0.24 0.24 Matched[309]
YBR078W ECM33 "GPI-anchored protein of unknown function, has a possible role in apical bud growth; GPI-anchoring on the plasma membrane crucial to function; phosphorylated in mitochondria; similar to Sps2p and Pst1p" Verified chr2:393118-394854 393118-393175,393506-394854 99.3% 5807.96 5810.11 5606.80 5527.34 2260.04 2012.35 5809.04 5567.07 2136.20 21.44 22.60 8.85 -1.38 -1.42 Frag>80[310,311,312]
YBR079C RPG1 "Subunit of the core complex of translation initiation factor 3(eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes" Verified chr2:395377-398271 395377-398271 99.1% 710.29 525.83 571.86 522.69 130.06 133.20 618.06 547.28 131.63 2.28 2.22 0.55 -2.06 -1.31 Matched[313]
YBR080C SEC18 ATPase required for the release of Sec17p during the 'priming' step in homotypic vacuole fusion and for ER to Golgi transport; homolog of the mammalian NSF Verified chr2:398608-400884 398608-400884 99.2% 251.07 253.72 240.00 248.85 229.37 215.20 252.39 244.42 222.28 0.93 0.99 0.92 -0.14 0.60 Matched[314]
YBR081C SPT7 "Subunit of the SAGA transcriptional regulatory complex, involved in proper assembly of the complex; also present as a C-terminally truncated form in the SLIK/SALSA transcriptional regulatory complex" Verified chr2:401247-405245 401247-405245 99.3% 116.29 124.85 113.52 111.00 82.31 112.01 120.57 112.26 97.16 0.45 0.46 0.40 -0.21 0.31 Matched[315]
YBR082C UBC4 "Ubiquitin-conjugating enzyme (E2), mediates degradation of short-lived and abnormal proteins; interacts with E3-CaM in ubiquitinating calmodulin; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response" Verified chr2:406622-407163 406622-407021,407117-407163 98.4% 1931.19 2038.10 2060.85 1835.66 7651.98 3760.02 1984.65 1948.25 5706.00 7.33 7.91 23.64 1.55 1.15 Matched[317]
YBR083W TEC1 "Transcription factor required for full Ty1 epxression, Ty1-mediated gene activation, and haploid invasive and diploid pseudohyphal growth; TEA/ATTS DNA-binding domain family member" Verified chr2:409163-410623 409163-410623 98.8% 391.38 606.11 464.11 399.69 451.64 267.38 498.74 431.90 359.51 1.84 1.75 1.49 -0.26 0.02 Matched[320]
YBR084W MIS1 "Mitochondrial C1-tetrahydrofolate synthase, involved in interconversion between different oxidation states of tetrahydrofolate (THF); provides activities of formyl-THF synthetase, methenyl-THF cyclohydrolase, and methylene-THF dehydrogenase" Verified chr2:411048-413975 411048-413975 98.4% 376.54 254.38 297.41 308.52 41.64 44.77 315.46 302.97 43.21 1.16 1.23 0.18 -2.81 -1.53 Matched[321]
YBR084C-A RPL19A "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl19Bp and has similarity to rat L19 ribosomal protein; rpl19a and rpl19b single null mutations result in slow growth, while the double null mutation is lethal" Verified chr2:414180-415255 414180-414747,415254-415255 67.7% 6930.45 5797.84 6033.69 4864.79 1625.05 1536.93 6364.15 5449.24 1580.99 23.49 22.12 6.55 -1.79 -2.61 Matched[322]
YBR085W AAC3 "Mitochondrial inner membrane ADP/ATP translocator, exchanges cytosolic ADP for mitochondrially synthesized ATP; expressed under anaerobic conditions; similar to Pet9p and Aac1p; has roles in maintenance of viability and in respiration" Verified chr2:415977-416900 415977-416900 98.6% 76.86 237.18 68.08 54.90 81.26 81.26 157.02 61.49 81.26 0.58 0.25 0.34 0.40 0.61 Matched[323]
YBR085C-A Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus Uncharacterized chr2:418901-419158 418901-419158 99.1% 308.95 414.53 387.16 273.75 16581.39 7958.29 361.74 330.45 12269.84 1.34 1.34 50.84 5.21 3.80 Matched[326]
YBR086C IST2 "Plasma membrane protein that may be involved in osmotolerance, localizes to the mother cell in small-budded cells and to the bud in medium- and large-budded cells; mRNA is transported to the bud tip by an actomyosin-driven process" Verified chr2:420195-423035 420195-423035 98.9% 517.13 560.90 571.23 563.04 345.94 453.07 539.02 567.13 399.50 1.99 2.30 1.66 -0.51 0.45 Covered/w/another[328]
YBR087W RFC5 "Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon" Verified chr2:423759-424823 423759-424823 98.9% 185.10 179.40 164.21 120.55 117.70 101.57 182.25 142.38 109.63 0.67 0.58 0.45 -0.38 0.11 Covered/w/another[328]
YBR089W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; almost completely overlaps the verified gene POL30" Dubious chr2:425177-425776 425177-425776 99.1% 682.69 501.09 679.32 543.12 174.88 95.85 591.89 611.22 135.36 2.18 2.48 0.56 -2.17 -0.00 Covered/w/another[328]
YBR088C POL30 "Proliferating cell nuclear antigen (PCNA), functions as the sliding clamp for DNA polymerase delta; may function as a docking site for other proteins required for mitotic and meiotic chromosomal DNA replication and for DNA repair" Verified chr2:424984-425760 424984-425760 99.0% 772.14 547.26 695.45 579.75 192.38 92.29 659.70 637.60 142.34 2.44 2.59 0.59 -2.16 -2.06 Covered/w/another[328]
YBR089C-A NHP6B "High-mobility group non-histone chromatin protein, functionally redundant with Nhp6Ap; homologous to mammalian high mobility group proteins 1 and 2; acts to recruit transcription factor Rcs1p to certain promoters" Verified chr2:426184-426868 426184-426510,426867-426868 99.2% 756.80 707.77 888.55 759.86 2086.56 1115.28 732.29 824.21 1600.92 2.70 3.35 6.63 0.96 0.32 Covered/w/another[329]
YBR090C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus Uncharacterized chr2:426327-427052 426327-427052 99.0% 194.74 159.96 203.08 200.30 520.23 265.68 177.35 201.69 392.95 0.65 0.82 1.63 0.96 0.74 Covered/w/another[329]
YBR091C MRS5 "Essential protein of the inner mitochondrial membrane, peripherally localized; component of the TIM22 complex, which is a twin-pore translocase that mediates insertion of numerous multispanning inner membrane proteins" Verified chr2:427149-427478 427149-427478 99.3% 222.82 189.24 164.82 149.56 143.46 100.72 206.03 157.19 122.09 0.76 0.64 0.51 -0.36 -0.77 Covered/w/another[329]
YBR092C PHO3 "Constitutively expressed acid phosphatase similar to Pho5p; brought to the cell surface by transport vesicles; hydrolyzes thiamin phosphates in the periplasmic space, increasing cellular thiamin uptake; expression is repressed by thiamin" Verified chr2:427692-429095 427692-429095 70.1% 596.54 456.30 368.90 353.66 97.56 85.37 526.42 361.28 91.46 1.94 1.47 0.38 -1.98 -1.52 Covered/w/another[329]
YBR093C PHO5 Repressible acid phosphatase (1 of 3) that also mediates extracellular nucleotide-derived phosphate hydrolysis; secretory pathway derived cell surface glycoprotein; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2 Verified chr2:429542-430945 429542-430945 64.6% 742.38 603.39 721.42 572.51 164.36 132.37 672.89 646.96 148.37 2.48 2.63 0.61 -2.12 -1.42 Covered/w/another[329]
YBR094W PBY1 Putative tubulin tyrosine ligase associated with P-bodies Verified chr2:432030-434291 432030-434291 98.8% 122.57 110.94 126.60 112.28 107.36 81.86 116.76 119.44 94.61 0.43 0.48 0.39 -0.34 -0.09 Frag<80[331]
YBR095C RXT2 Subunit of the histone deacetylase Rpd3L complex; possibly involved in cell fusion and invasive growth Verified chr2:434400-435692 434400-435692 99.2% 111.48 123.95 105.24 82.63 109.92 48.33 117.72 93.94 79.13 0.43 0.38 0.33 -0.25 -0.04 Matched[332]
YBR096W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the ER Uncharacterized chr2:436015-436707 436015-436707 99.0% 396.45 329.41 424.15 317.75 789.99 448.93 362.93 370.95 619.46 1.34 1.51 2.57 0.74 0.47 Frag>80[333,334]
YBR097W VPS15 Myristoylated serine/threonine protein kinase involved in vacuolar protein sorting; functions as a membrane-associated complex with Vps34p; active form recruits Vps34p to the Golgi membrane; interacts with the GDP-bound form of Gpa1p Verified chr2:436945-441309 436945-441309 99.1% 49.49 54.58 43.48 46.95 46.95 50.42 52.04 45.22 48.68 0.19 0.18 0.20 0.11 0.25 Covered/w/another[335]
YBR098W MMS4 Subunit of the structure-specific Mms4p-Mus81p endonuclease that cleaves branched DNA; involved in recombination and DNA repair Verified chr2:441509-443584 441509-443584 98.7% 55.63 61.00 40.01 36.11 88.32 38.55 58.31 38.06 63.44 0.22 0.15 0.26 0.74 0.80 Covered/w/another[335]
YBR099C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene MMS4" Dubious chr2:442918-443301 442918-443301 98.7% 79.17 116.12 34.31 31.67 200.57 50.14 97.65 32.99 125.36 0.36 0.13 0.52 1.93 1.37 Covered/w/another[335]
YBR101C FES1 "Hsp70 (Ssa1p) nucleotide exchange factor, cytosolic homolog of Sil1p, which is the nucleotide exchange factor for BiP (Kar2p) in the endoplasmic reticulum" Verified chr2:443815-444687 443815-444687 99.2% 307.26 233.33 301.49 323.43 5017.86 4526.93 270.30 312.46 4772.39 1.00 1.27 19.77 3.93 3.54 Frag<80[336]
YBR102C EXO84 "Essential protein with dual roles in spliceosome assembly and exocytosis; the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p) mediates polarized targeting of secretory vesicles to active sites of exocytosis" Verified chr2:445056-447317 445056-447317 99.3% 94.84 109.53 92.17 82.37 97.95 87.71 102.18 87.27 92.83 0.38 0.35 0.38 0.09 0.50 Matched[337]
YBR103W SIF2 "WD40 repeat-containing subunit of the Set3C histone deacetylase complex, which represses early/middle sporulation genes; antagonizes telomeric silencing; binds specifically to the Sir4p N-terminus" Verified chr2:447703-449310 447703-449310 98.4% 137.09 133.93 125.08 129.50 149.09 112.45 135.51 127.29 130.77 0.50 0.52 0.54 0.04 0.30 Matched[338]
YBR103C-A "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; identified by homology to related yeast" Dubious chr2:449314-449457 449314-449457 98.3% 7.07 14.13 0.00 7.07 21.20 7.07 10.60 3.53 14.13 0.04 0.01 0.06 2.00 -1.05 Covered/w/another[338]
YBR104W YMC2 "Mitochondrial protein, putative inner membrane transporter with a role in oleate metabolism and glutamate biosynthesis; member of the mitochondrial carrier (MCF) family; has similarity with Ymc1p" Verified chr2:449661-450650 449661-450650 98.5% 151.70 168.10 74.82 65.60 9.22 5.12 159.90 70.21 7.17 0.59 0.29 0.03 -3.29 -2.97 Matched[339]
YBR105C VID24 "Peripheral membrane protein located at Vid (vacuole import and degradation) vesicles; regulates fructose-1,6-bisphosphatase (FBPase) targeting to the vacuole; involved in proteasome-dependent catabolite degradation of FBPase" Verified chr2:450875-451963 450875-451963 98.8% 247.11 312.13 192.30 142.13 258.25 154.21 279.62 167.22 206.23 1.03 0.68 0.85 0.30 0.64 Matched[340]
YBR106W PHO88 "Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations" Verified chr2:452652-453218 452652-453218 98.6% 3191.18 2484.61 2774.39 2772.60 1316.54 901.54 2837.89 2773.50 1109.04 10.48 11.26 4.60 -1.32 -1.93 Matched[342]
YBR107C IML3 "Protein with a role in kinetochore function, localizes to the outer kinetochore in a Ctf19p-dependent manner, interacts with Chl4p and Ctf19p" Verified chr2:453787-454524 453787-454524 99.2% 118.88 159.87 124.35 107.95 114.78 75.15 139.38 116.15 94.97 0.51 0.47 0.39 -0.29 0.23 Matched[343]
YBR108W Protein interacting with Rsv167p Uncharacterized chr2:454816-457659 454816-457659 98.0% 81.84 77.17 83.27 82.91 110.19 134.96 79.50 83.09 122.57 0.29 0.34 0.51 0.56 0.95 Matched[344]
YBR109C CMD1 "Calmodulin; Ca++ binding protein that regulates Ca++ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca++ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin" Verified chr2:457913-458356 457913-458356 99.1% 1340.91 1406.82 1329.55 1256.82 1656.82 1209.09 1373.86 1293.18 1432.95 5.07 5.25 5.94 0.15 0.18 Matched[345]
YBR109W-A Putative protein of unknown function; questionable ORF from MIPS Dubious chr2:458602-458826 458602-458826 99.2% 35.85 26.89 53.78 35.85 40.34 31.37 31.37 44.82 35.85 0.12 0.18 0.15 -0.32 NaN Covered/w/another[346]
YBR110W ALG1 "Mannosyltransferase, involved in asparagine-linked glycosylation in the endoplasmic reticulum (ER); essential for viability, mutation is functionally complemented by human ortholog" Verified chr2:458866-460215 458866-460215 99.0% 221.50 193.07 223.75 212.52 146.67 127.96 207.28 218.13 137.32 0.77 0.89 0.57 -0.67 -0.43 Matched[346]
YBR111C YSA1 Nudix hydrolase family member with ADP-ribose pyrophosphatase activity Verified chr2:461172-461867 461172-461867 99.1% 896.09 1287.58 994.68 962.78 2067.67 1358.63 1091.83 978.73 1713.15 4.03 3.97 7.10 0.81 0.72 Frag>80[347,348,349]
YBR111W-A SUS1 Protein involved in mRNA export coupled transcription activation; component of the SAGA histone acetylase complex Verified chr2:462133-462573 462133-462203,462284-462423,462494-462573 98.9% 243.34 253.77 243.34 219.00 542.29 326.77 248.55 231.17 434.53 0.92 0.94 1.80 0.91 NaN Matched[349]
YBR113W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene CYC8" Dubious chr2:465560-466042 465560-466042 95.6% 127.79 134.28 129.95 101.80 58.48 119.12 131.04 115.87 88.80 0.48 0.47 0.37 -0.38 -0.19 Covered/w/another[350]
YBR112C CYC8 "General transcriptional co-repressor, acts together with Tup1p; also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters" Verified chr2:462864-465764 462864-465764 92.6% 321.99 326.46 294.82 281.04 248.29 338.00 324.22 287.93 293.14 1.20 1.17 1.21 0.03 0.62 Matched[350]
YBR114W RAD16 Protein that recognizes and binds damaged DNA in an ATP-dependent manner (with Rad7p) during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex Verified chr2:467242-469614 467242-469614 98.5% 46.19 53.46 44.48 34.64 156.95 124.02 49.82 39.56 140.49 0.18 0.16 0.58 1.83 1.66 Matched[352]
YBR115C LYS2 "Alpha aminoadipate reductase, catalyzes the reduction of alpha-aminoadipate to alpha-aminoadipate 6-semialdehyde, which is the fifth step in biosynthesis of lysine; activation requires posttranslational phosphopantetheinylation by Lys5p" Verified chr2:469742-473920 469742-473920 99.0% 180.47 261.89 145.68 127.56 44.70 52.18 221.18 136.62 48.44 0.82 0.55 0.20 -1.50 -0.71 Matched[353]
YBR116C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene TKL2" Dubious chr2:474193-474720 474193-474720 98.7% 15.35 28.78 17.27 11.51 456.59 341.49 22.06 14.39 399.04 0.08 0.06 1.65 4.79 3.22 Covered/w/another[354]
YBR117C TKL2 "Transketolase, similar to Tkl1p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids" Verified chr2:474386-476431 474386-476431 98.8% 34.62 28.68 18.30 10.38 270.50 270.00 31.65 14.34 270.25 0.12 0.06 1.12 4.24 4.45 Covered/w/another[354]
YBR118W TEF2 Translational elongation factor EF-1 alpha; also encoded by TEF1; functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes Verified chr2:477665-479041 477665-479041 2.7% 12710.71 11015.95 10551.25 9567.20 9321.18 6478.36 11863.33 10059.23 7899.77 43.79 40.83 32.73 -0.35 -1.75 Frag<80[355,356]
YBR119W MUD1 "U1 snRNP A protein, homolog of human U1-A; involved in nuclear mRNA splicing" Verified chr2:479332-480317 479332-479339,479429-480317 98.7% 135.48 151.28 150.16 123.06 188.54 79.03 143.38 136.61 133.78 0.53 0.55 0.55 -0.03 0.07 Matched[357]
YBR120C CBP6 Mitochondrial translational activator of the COB mRNA; phosphorylated Verified chr2:480429-480917 480429-480917 99.2% 199.88 187.52 249.33 228.73 346.18 236.97 193.70 239.03 291.58 0.72 0.97 1.21 0.29 0.24 Covered/w/another[357]
YBR121C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely contianed within the verified gene GRS1; identified by expression profiling and mass spectrometry" Dubious chr2:482320-482478 482320-482478 99.0% 1651.67 1003.71 1264.16 1467.44 590.79 476.44 1327.69 1365.80 533.62 4.90 5.54 2.21 -1.36 NaN Covered/w/another[359]
YBR121C GRS1 Cytoplasmic and mitochondrial glycyl-tRNA synthase that ligates glycine to the cognate anticodon bearing tRNA; transcription termination factor that may interact with the 3'-end of pre-mRNA to promote 3'-end formation Verified chr2:481358-483361 481358-483361 99.1% 1710.62 1238.77 1486.53 1490.05 562.48 551.91 1474.70 1488.29 557.20 5.44 6.04 2.31 -1.42 -1.12 Frag>80[358,359]
YBR122C MRPL36 Mitochondrial ribosomal protein of the large subunit; overproduction suppresses mutations in the COX2 leader peptide-encoding region Verified chr2:483964-484497 483964-484497 99.1% 508.19 481.74 511.96 460.96 623.43 472.29 494.96 486.46 547.86 1.83 1.97 2.27 0.17 -0.05 Frag>80[360,361]
YBR124W Putative protein of unknown function Dubious chr2:486501-486860 486501-486860 98.7% 61.94 56.30 59.12 19.71 28.15 28.15 59.12 39.41 28.15 0.22 0.16 0.12 -0.49 -0.29 Covered/w/another[362]
YBR123C TFC1 One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes; human homolog is TFIIIC-63 Verified chr2:484736-486685 484736-486685 99.2% 123.07 115.83 113.76 109.62 96.18 79.11 119.45 111.69 87.65 0.44 0.45 0.36 -0.35 -0.02 Matched[362]
YBR125C PTC4 Cytoplasmic type 2C protein phosphatase; identified as a high-copy number suppressor of the synthetic lethality of a cnb1 mpk1 double deletion; overexpression decreases high-osmolarity induced Hog1p phosphorylation and kinase activity Verified chr2:487193-488374 487193-488374 99.2% 120.30 92.14 122.86 72.52 114.33 46.92 106.22 97.69 80.63 0.39 0.40 0.33 -0.28 -0.20 Matched[363]
YBR126C TPS1 "Synthase subunit of trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; also found in a monomeric form; expression is induced by the stress response and repressed by the Ras-cAMP pathway" Verified chr2:488899-490386 488899-490386 98.9% 496.56 837.56 955.76 966.63 6085.76 5359.60 667.06 961.20 5722.68 2.46 3.90 23.71 2.57 1.78 Frag>80[364,365]
YBR126W-A "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YBR126W-B; identified by gene-trapping, microarray analysis, and genome-wide homology searches" Dubious chr2:490844-491050 490844-491050 98.3% 1322.14 2383.78 1872.62 1779.23 4777.39 3396.27 1852.96 1825.93 4086.83 6.84 7.41 16.93 1.16 NaN Matched[366]
YBR126W-B Identified by SAGE Dubious chr2:490921-491064 490921-491064 98.1% 1464.62 2653.30 2165.09 2115.57 5490.57 4160.38 2058.96 2140.33 4825.47 7.60 8.69 19.99 1.17 NaN Matched[366]
YBR127C VMA2 "Subunit B of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; contains nucleotide binding sites; also detected in the cytoplasm" Verified chr2:491263-492816 491263-492816 99.1% 2737.10 3530.18 2594.21 2794.26 1919.35 1989.50 3133.64 2694.24 1954.42 11.57 10.94 8.10 -0.46 -0.79 Matched[367]
YBR128C ATG14 "Subunit of an autophagy-specific phosphatidylinositol 3-kinase complex (with Vps34p, Vps15p, and Vps30p) required for organization of a pre-autophagosomal structure; ATG14 transcription is activated by Gln3p during nitrogen starvation" Verified chr2:493075-494109 493075-494109 99.2% 37.01 74.02 48.70 37.98 143.17 72.07 55.51 43.34 107.62 0.20 0.18 0.45 1.31 0.42 Matched[368]
YBR129C OPY1 "Protein of unknown function, overproduction blocks cell cycle arrest in the presence of mating pheromone; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr2:494347-495333 494347-495333 99.2% 174.65 216.53 184.87 153.20 157.29 77.62 195.59 169.04 117.46 0.72 0.69 0.49 -0.53 -0.68 Matched[369]
YBR130C SHE3 Protein that acts as an adaptor between Myo4p and the She2p-mRNA complex; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud; also required for cortical ER inheritance Verified chr2:495586-496863 495586-496863 99.2% 242.19 265.86 252.45 230.36 177.50 161.73 254.03 241.40 169.61 0.94 0.98 0.70 -0.51 0.08 Matched[370]
YBR131W CCZ1 "Protein involved in vacuolar assembly, essential for autophagy and the cytoplasm-to-vacuole pathway" Verified chr2:497157-499271 497157-499271 98.8% 58.83 67.44 38.27 31.09 42.09 37.79 63.14 34.68 39.94 0.23 0.14 0.17 0.20 0.34 Matched[371]
YBR131C-A "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YBR131W. Identified by gene-trapping, microarray analysis, and genome-wide homology searches" Dubious chr2:497644-497733 497644-497733 98.5% 11.28 22.57 22.57 22.57 22.57 22.57 16.93 22.57 22.57 0.06 0.09 0.09 0.00 NaN Covered/w/another[371]
YBR132C AGP2 "High affinity polyamine permease, preferentially uses spermidine over putrescine; expression is down-regulated by osmotic stress; plasma membrane carnitine transporter, also functions as a low-affinity amino acid permease" Verified chr2:499646-501436 499646-501436 98.8% 88.71 132.22 120.92 137.87 227.71 241.84 110.46 129.39 234.77 0.41 0.53 0.97 0.86 1.15 Covered/w/another[372]
YBR134W "Dubious open reading frame, unlikely to encode a functional protein; based on available experimental and comparative sequence data" Dubious chr2:504237-504638 504237-504638 99.0% 27.65 37.71 25.14 17.60 32.68 25.14 32.68 21.37 28.91 0.12 0.09 0.12 0.44 0.02 Overlap[372]
YBR133C HSL7 "Protein arginine N-methyltransferase that exhibits septin and Hsl1p-dependent bud neck localization and periodic Hsl1p-dependent phosphorylation; required along with Hsl1p for bud neck recruitment, phosphorylation, and degradation of Swe1p" Verified chr2:501798-504281 501798-504281 98.9% 157.09 166.45 138.37 77.33 108.26 55.76 161.77 107.85 82.01 0.60 0.44 0.34 -0.40 -0.14 Covered/w/another[372]
YBR135W CKS1 "Cyclin-dependent protein kinase regulatory subunit and adaptor; modulates proteolysis of M-phase targets through interactions with the proteasome; role in transcriptional regulation, recruiting proteasomal subunits to target gene promoters" Verified chr2:504848-505300 504848-505300 94.6% 305.60 261.28 321.93 207.62 331.26 177.29 283.44 264.77 254.28 1.05 1.07 1.05 -0.06 0.04 Matched[373]
YBR136W MEC1 Genome integrity checkpoint protein and PI kinase superfamily member; signal transducer required for cell cycle arrest and transcriptional responses prompted by damaged or unreplicated DNA; monitors and participates in meiotic recombination Verified chr2:505662-512768 505662-512768 98.9% 27.31 24.04 15.93 16.78 16.93 25.32 25.67 16.36 21.12 0.09 0.07 0.09 0.37 0.53 Frag<80[374]
YBR137W Protein of unknown function; localized to the cytoplasm; binds to Replication Protein A (RPA); YBR137W is not an essential gene Uncharacterized chr2:513038-513577 513038-513577 98.3% 190.28 207.24 280.71 211.01 1083.29 687.65 198.76 245.86 885.47 0.73 1.00 3.67 1.85 1.56 Matched[375]
YBR138C "Cytoplasmic protein of unknown function, potentially phosphorylated by Cdc28p; YBR138C is not an essential gene" Uncharacterized chr2:513756-515330 513756-515330 99.2% 72.98 65.30 73.62 65.94 165.80 99.23 69.14 69.78 132.52 0.26 0.28 0.55 0.93 0.71 Matched[376]
YBR139W "Putative serine type carboxypeptidase with a role in phytochelatin synthesis; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; expression induced by nitrogen limitation in a GLN3, GAT1-independent manner" Verified chr2:515658-517184 515658-517184 98.9% 327.84 513.95 427.19 405.33 1183.54 951.07 420.90 416.26 1067.31 1.55 1.69 4.42 1.36 1.46 Matched[377]
YBR140C IRA1 "GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, mediates membrane association of adenylate cyclase" Verified chr2:517344-526622 517344-526622 99.0% 88.47 95.55 66.60 61.70 44.62 70.52 92.01 64.15 57.57 0.34 0.26 0.24 -0.16 -0.18 Frag>80[378,379]
YBR141W-A "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the uncharacterized ORF YBR141C; identified by gene-trapping, microarray analysis, and genome-wide homology searching" Dubious chr2:527161-527256 527161-527256 98.4% 74.07 42.33 31.75 52.91 63.49 10.58 58.20 42.33 37.04 0.21 0.17 0.15 -0.19 NaN Covered/w/another[380]
YBR141C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; YBR141C is not an essential gene Uncharacterized chr2:527019-528032 527019-528032 99.2% 56.67 34.80 42.75 38.78 39.77 24.86 45.74 40.77 32.31 0.17 0.17 0.13 -0.34 -2.49 Covered/w/another[380]
YBR142W MAK5 "Essential nucleolar protein, putative DEAD-box RNA helicase required for maintenance of M1 dsRNA virus; involved in biogenesis of large (60S) ribosomal subunits" Verified chr2:528311-530632 528311-530632 98.7% 188.49 81.16 114.32 95.55 17.89 11.78 134.82 104.94 14.84 0.50 0.43 0.06 -2.82 -2.91 Matched[381]
YBR143C SUP45 Polypeptide release factor involved in translation termination; mutant form acts as a recessive omnipotent suppressor Verified chr2:530863-532176 530863-532176 99.2% 1369.78 958.47 1164.12 1086.62 326.14 207.19 1164.12 1125.37 266.67 4.30 4.57 1.10 -2.08 -1.89 Matched[382]
YBR144C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YBR144C is not an essential gene" Dubious chr2:533229-533543 533229-533543 98.8% 3.21 0.00 0.00 0.00 6.43 6.43 1.61 0.00 6.43 0.01 0.00 0.03 Inf 0.11
YBR145W ADH5 Alcohol dehydrogenase isoenzyme V; involved in ethanol production Verified chr2:533756-534811 533756-534811 97.9% 280.39 631.35 300.69 320.99 128.59 85.08 455.87 310.84 106.84 1.68 1.26 0.44 -1.54 -1.70 Frag>80[383,384]
YBR146W MRPS9 Mitochondrial ribosomal protein of the small subunit Verified chr2:535254-536090 535254-536090 98.7% 412.77 457.56 456.35 473.29 470.87 291.72 435.16 464.82 381.30 1.61 1.89 1.58 -0.29 0.26 Matched[385]
YBR147W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays fluconazole resistance" Uncharacterized chr2:536569-537459 536569-537459 99.0% 35.15 98.65 52.16 75.97 290.28 200.70 66.90 64.07 245.49 0.25 0.26 1.02 1.94 1.61 Matched[386]
YBR148W YSW1 Protein expressed specifically in spores Verified chr2:537870-539699 537870-539699 98.7% 22.14 24.36 21.04 15.50 29.34 37.09 23.25 18.27 33.22 0.09 0.07 0.14 0.86 0.87 Frag>80[387,388]
YBR149W ARA1 "NADP+ dependent arabinose dehydrogenase, involved in carbohydrate metabolism; purified as homodimer; naturally occurs with a N-terminus degradation product" Verified chr2:539981-541015 539981-541015 98.7% 986.01 1388.44 1169.11 1167.15 3170.49 2425.36 1187.22 1168.13 2797.93 4.38 4.74 11.59 1.26 1.24 Matched[389]
YBR150C TBS1 "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr2:541203-544487 541203-544487 97.4% 45.03 50.34 38.77 40.34 57.85 46.90 47.68 39.55 52.37 0.18 0.16 0.22 0.41 0.21 Matched[390]
YBR151W APD1 "Protein of unknown function, required for normal localization of actin patches and for normal tolerance of sodium ions and hydrogen peroxide; localizes to both cytoplasm and nucleus" Verified chr2:545022-545972 545022-545972 98.6% 530.11 680.50 634.64 638.90 917.29 641.04 605.31 636.77 779.17 2.23 2.58 3.23 0.29 0.14 Matched[391]
YBR152W SPP381 "mRNA splicing factor, component of U4/U6.U5 tri-snRNP; interacts genetically and physically with Prp38p" Verified chr2:546370-547245 546370-547245 98.1% 72.16 59.35 51.21 39.57 25.60 33.75 65.76 45.39 29.68 0.24 0.18 0.12 -0.61 -0.38 Covered/w/another[392]
YBR153W RIB7 Diaminohydroxyphoshoribosylaminopyrimidine deaminase; catalyzes the second step of the riboflavin biosynthesis pathway Verified chr2:547454-548188 547454-548188 98.6% 150.35 179.32 143.46 100.70 86.90 51.04 164.84 122.08 68.97 0.61 0.50 0.29 -0.82 -0.70 Covered/w/another[392]
YBR154C RPB5 "RNA polymerase subunit ABC27, common to RNA polymerases I, II, and III; contacts DNA and affects transactivation" Verified chr2:548356-549003 548356-549003 99.3% 886.18 601.67 618.77 592.34 321.82 212.99 743.93 605.56 267.41 2.75 2.46 1.11 -1.18 -1.24 Matched[393]
YBR155W CNS1 "TPR-containing co-chaperone; binds both Hsp82p (Hsp90) and Ssa1p (Hsp70) and stimulates the ATPase activity of SSA1, ts mutants reduce Hsp82p function while over expression suppresses the phenotypes of an HSP82 ts allele and a cpr7 deletion" Verified chr2:549765-550922 549765-550922 98.3% 195.02 101.02 126.50 112.45 47.44 28.11 148.02 119.47 37.77 0.55 0.48 0.16 -1.66 -1.25 Covered/w/another[394]
YBR156C SLI15 "Subunit of the Ipl1p-Sli15p-Bir1p complex that regulates kinetochore-microtubule attachments, activation of the spindle tension checkpoint, and mitotic spindle disassembly; regulates the activity and localization of the Ipl1p aurora kinase" Verified chr2:551098-553194 551098-553194 99.1% 76.47 86.57 65.41 68.78 51.46 51.46 81.52 67.10 51.46 0.30 0.27 0.21 -0.38 0.01 Covered/w/another[394]
YBR157C ICS2 "Protein of unknown function; null mutation does not confer any obvious defects in growth, spore germination, viability, or carbohydrate utilization" Verified chr2:553537-554304 553537-554304 99.0% 169.71 303.90 178.92 148.66 439.40 298.64 236.80 163.79 369.02 0.87 0.66 1.53 1.17 1.37 Frag>80[395,396]
YBR158W AMN1 "Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN)" Verified chr2:556543-558192 556543-558192 98.8% 674.69 607.84 550.18 472.28 394.39 269.88 641.26 511.23 332.13 2.37 2.08 1.38 -0.62 -0.49 Matched[398]
YBR159W "Microsomal beta-keto-reductase; contains oleate response element (ORE) sequence in the promoter region; mutants exhibit reduced VLCFA synthesis, accumulate high levels of dihydrosphingosine, phytosphingosine and medium-chain ceramides" Verified chr2:558679-559722 558679-559722 98.9% 846.45 850.33 838.71 843.55 748.64 558.82 848.39 841.13 653.73 3.13 3.41 2.71 -0.36 -0.32 Matched[399]
YBR160W CDC28 Catalytic subunit of the main cell cycle cyclin-dependent kinase (CDK); alternately associates with G1 cyclins (CLNs) and G2/M cyclins (CLBs) which direct the CDK to specific substrates Verified chr2:560072-560968 560072-560968 98.7% 211.20 160.38 228.14 225.88 324.14 220.24 185.79 227.01 272.19 0.69 0.92 1.13 0.26 0.62 Matched[400]
YBR161W CSH1 "Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synthase, forms a complex with probable regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Sur1p" Verified chr2:561629-562759 561629-562759 98.9% 122.50 136.81 148.44 134.13 355.89 255.74 129.66 141.28 305.81 0.48 0.57 1.27 1.11 1.22 Matched[402]
YBR162C TOS1 "Covalently-bound cell wall protein of unknown function; identified as a cell cycle regulated SBF target gene; deletion mutants are highly resistant to treatment with beta-1,3-glucanase; has sequence similarity to YJL171C" Verified chr2:563198-564565 563198-564565 98.6% 3197.63 2946.98 3086.39 2887.65 1112.35 1108.64 3072.30 2987.02 1110.49 11.34 12.12 4.60 -1.43 -0.89 Frag>80[403,404,405]
YBR162W-A YSY6 Protein whose expression suppresses a secretory pathway mutation in E. coli; has similarity to the mammalian RAMP4 protein involved in secretion Verified chr2:565226-565423 565226-565423 98.4% 1098.84 996.15 1032.09 836.97 616.17 344.03 1047.50 934.53 480.10 3.87 3.79 1.99 -0.96 -1.63 Matched[406]
YBR163W DEM1 "Protein of unknown function, shows similarity to RNA-processing protein Pta1p" Verified chr2:565718-567475 565718-567475 99.0% 157.51 134.51 121.87 99.45 70.13 52.31 146.01 110.66 61.22 0.54 0.45 0.25 -0.85 -0.62 Matched[407]
YBR164C ARL1 "Soluble GTPase with a role in regulation of membrane traffic; regulates potassium influx; G protein of the Ras superfamily, similar to ADP-ribosylation factor" Verified chr2:567870-568421 567870-568421 99.3% 655.01 552.84 691.50 567.43 521.82 348.49 603.92 629.47 435.15 2.23 2.56 1.80 -0.53 -0.70 Matched[408]
YBR165W UBS1 Ubiquitin-conjugating enzyme suppressor that functions as a general positive regulator of Cdc34p activity; nuclear protein that may represent a link between nucleocytoplasmic transport and ubiquitin ligase activity Verified chr2:568847-569680 568847-569680 98.9% 111.57 84.89 124.91 98.23 154.01 94.59 98.23 111.57 124.30 0.36 0.45 0.52 0.16 0.24 Covered/w/another[409]
YBR166C TYR1 "Prephenate dehydrogenase involved in tyrosine biosynthesis, expression is dependent on phenylalanine levels" Verified chr2:569837-571195 569837-571195 99.3% 174.20 219.42 181.61 170.49 142.32 99.33 196.81 176.05 120.83 0.73 0.71 0.50 -0.54 -0.62 Covered/w/another[409]
YBR167C POP7 "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends" Verified chr2:571463-571885 571463-571885 99.4% 95.12 121.27 116.52 90.36 107.00 85.60 108.19 103.44 96.30 0.40 0.42 0.40 -0.10 0.00 Covered/w/another[410]
YBR168W PEX32 "Peroxisomal integral membrane protein, involved in negative regulation of peroxisome size; partially functionally redundant with Pex31p; genetic interactions suggest action at a step downstream of steps mediated by Pex28p and Pex29p" Verified chr2:572366-573607 572366-573607 98.9% 70.84 95.26 87.94 78.98 116.43 87.12 83.05 83.46 101.78 0.31 0.34 0.42 0.29 0.86 Covered/w/another[410]
YBR169C SSE2 Member of the heat shock protein 70 (HSP70) family; may be involved in protein folding; localized to the cytoplasm; highly homologous to the heat shock protein Sse1p Verified chr2:573910-575991 573910-575991 98.9% 109.28 264.71 151.05 203.02 2142.43 2305.14 187.00 177.04 2223.79 0.69 0.72 9.21 3.65 3.49 Frag>80[411,412]
YBR170C NPL4 "Endoplasmic reticulum and nuclear membrane protein, forms a complex with Cdc48p and Ufd1p that recognizes ubiquitinated proteins in the endoplasmic reticulum and delivers them to the proteasome for degradation" Verified chr2:576339-578081 576339-578081 99.2% 123.80 109.34 112.81 102.98 248.76 172.40 116.57 107.89 210.58 0.43 0.44 0.87 0.96 0.89 Matched[413]
YBR171W SEC66 "Non-essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER" Verified chr2:578359-578979 578359-578979 98.6% 620.79 517.87 537.47 499.90 442.72 261.38 569.33 518.68 352.05 2.10 2.11 1.46 -0.56 -0.63 Matched[414]
YBR172C SMY2 Protein of unknown function that interacts with Myo2p; has similarity to S. pombe Mpd2 Verified chr2:579145-581367 579145-581367 98.9% 237.39 226.93 187.82 178.72 72.76 60.03 232.16 183.27 66.40 0.86 0.74 0.28 -1.46 -0.85 Matched[415]
YBR173C UMP1 Short-lived chaperone required for correct maturation of the 20S proteasome; may inhibit premature dimerization of proteasome half-mers; degraded by proteasome upon completion of its assembly Verified chr2:581721-582167 581721-582167 98.7% 578.23 487.53 526.08 444.44 884.35 455.78 532.88 485.26 670.07 1.97 1.97 2.78 0.47 0.63 Matched[416]
YBR175W SWD3 "Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5" Verified chr2:582403-583350 582403-583350 98.7% 125.03 107.93 107.93 80.15 125.03 67.33 116.48 94.04 96.18 0.43 0.38 0.40 0.03 -0.27 Covered/w/another[417]
YBR174C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YBR175W; null mutant is viable and sporulation defective" Dubious chr2:582333-582647 582333-582647 99.0% 83.41 44.91 54.54 44.91 67.37 64.16 64.16 49.73 65.77 0.24 0.20 0.27 0.40 -0.56 Covered/w/another[417]
YBR176W ECM31 "Ketopantoate hydroxymethyltransferase, required for pantothenic acid biosynthesis, converts 2-oxoisovalerate into 2-dehydropantoate" Verified chr2:583715-584653 583715-584653 98.9% 104.50 90.50 99.12 65.72 129.28 100.19 97.50 82.42 114.74 0.36 0.33 0.48 0.48 0.49 Covered/w/another[417]
YBR178W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YBR177C" Dubious chr2:586066-586440 586066-586440 98.8% 64.75 37.77 102.52 83.63 148.38 175.36 51.26 93.08 161.87 0.19 0.38 0.67 0.80 1.05
YBR177C EHT1 Acyl-coenzymeA:ethanol O-acyltransferase that plays a minor role in medium-chain fatty acid ethyl ester biosynthesis; contains esterase activity; localizes to lipid particles and the mitochondrial outer membrane Verified chr2:584802-586157 584802-586157 98.9% 346.58 205.71 417.39 452.42 716.27 766.96 276.15 434.91 741.61 1.02 1.77 3.07 0.77 1.21 Matched[418]
YBR179C FZO1 Mitochondrial integral membrane protein involved in mitochondrial fusion and maintenance of the mitochondrial genome; contains N-terminal GTPase domain Verified chr2:586542-589109 586542-589109 99.1% 122.58 99.40 106.08 118.26 101.76 83.68 110.99 112.17 92.72 0.41 0.46 0.38 -0.27 0.28 Matched[419]
YBR180W DTR1 "Multidrug resistance dityrosine transporter of the major facilitator superfamily, essential for spore wall synthesis, facilitates the translocation of bisformyl dityrosine through the prospore membrane" Verified chr2:589736-591454 589736-591454 99.0% 8.23 5.88 5.29 5.29 7.64 4.70 7.05 5.29 6.17 0.03 0.02 0.03 0.22 -0.40
YBR181C RPS6B Protein component of the small (40S) ribosomal subunit; identical to Rps6Ap and has similarity to rat S6 ribosomal protein Verified chr2:591707-592769 591707-592411,592764-592769 12.8% 5654.16 4193.96 5357.73 3930.47 1251.60 845.38 4924.06 4644.10 1048.49 18.18 18.85 4.34 -2.15 -2.66 Frag<80[420,421,422]
YBR182C SMP1 Putative transcription factor involved in regulating the response to osmotic stress; member of the MADS-box family of transcription factors Verified chr2:593501-594859 593501-594859 98.9% 15.62 12.64 11.16 10.41 28.26 14.13 14.13 10.78 21.20 0.05 0.04 0.09 0.97 0.78
YBR182C-A "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr2:595356-595550 595356-595550 99.2% 10.34 5.17 5.17 5.17 15.51 20.68 7.75 5.17 18.09 0.03 0.02 0.07 1.81 NaN
YBR183W YPC1 "Alkaline ceramidase that also has reverse (CoA-independent) ceramide synthase activity, catalyzes both breakdown and synthesis of phytoceramide; overexpression confers fumonisin B1 resistance" Verified chr2:596110-597060 596110-597060 98.8% 112.77 157.45 203.19 185.11 668.09 465.96 135.11 194.15 567.02 0.50 0.79 2.35 1.55 1.39 Matched[423]
YBR184W Putative protein of unknown function; YBR184W is not an essential gene Uncharacterized chr2:597358-598929 597358-598929 98.8% 34.11 19.95 28.32 21.24 29.61 23.82 27.03 24.78 26.71 0.10 0.10 0.11 0.11 -0.31 Matched[424]
YBR185C MBA1 Protein involved in assembly of mitochondrial respiratory complexes; may act as a receptor for proteins destined for export from the mitochondrial matrix to the inner membrane Verified chr2:599118-599954 599118-599954 99.1% 166.37 172.39 189.27 202.53 268.84 173.60 169.38 195.90 221.22 0.63 0.80 0.92 0.18 -0.02 Matched[425]
YBR186W PCH2 "Nucleolar component of the pachytene checkpoint, which prevents chromosome segregation when recombination and chromosome synapsis are defective; also represses meiotic interhomolog recombination in the rDNA" Verified chr2:600548-602355 600548-602098,602212-602355 98.7% 32.28 34.67 19.13 25.10 28.09 14.35 33.47 22.12 21.22 0.12 0.09 0.09 -0.06 1.59 Frag<80[426,427]
YBR187W GDT1 Putative protein of unknown function; expression is reduced in a gcr1 null mutant; GFP-fusion protein localizes to the vacuole; expression pattern and physical interactions suggest a possible role in ribosome biogenesis Uncharacterized chr2:602629-603471 602629-603471 98.8% 798.60 714.54 719.34 548.81 294.22 145.31 756.57 634.08 219.76 2.79 2.57 0.91 -1.53 -1.55 Matched[428]
YBR188C NTC20 "Member of a complex, including Prp19p, that binds to the spliceosome; required for pre-mRNA splicing" Verified chr2:603680-604102 603680-604102 99.3% 135.77 150.06 157.21 181.02 154.82 78.60 142.91 169.11 116.71 0.53 0.69 0.48 -0.54 -0.50 Matched[429]
YBR189W RPS9B Protein component of the small (40S) ribosomal subunit; nearly identical to Rps9Ap and has similarity to E. coli S4 and rat S9 ribosomal proteins Verified chr2:604503-605503 604503-604509,604923-605503 70.4% 11601.53 9669.55 10208.09 8725.30 1555.24 1557.66 10635.54 9466.69 1556.45 39.26 38.43 6.45 -2.60 -2.82 Matched[430]
YBR190W "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the verified ribosomal protein gene RPL21A/YBR191W" Dubious chr2:605961-606272 605961-606272 98.3% 61.97 32.62 58.71 29.36 26.09 16.31 47.30 44.03 21.20 0.17 0.18 0.09 -1.05 -1.65 Overlap[431]
YBR191W RPL21A "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl21Bp and has similarity to rat L21 ribosomal protein" Verified chr2:606265-607135 606265-606275,606664-607135 57.5% 10289.83 8360.04 9332.13 7751.57 1620.16 1173.72 9324.93 8541.85 1396.94 34.42 34.67 5.79 -2.61 -2.11 Matched[431]
YBR191W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr2:607144-607218 607144-607218 99.8% 6651.08 4661.10 4968.28 4514.19 1015.03 534.22 5656.09 4741.23 774.62 20.88 19.25 3.21 -2.61 NaN Covered/w/another[431]
YBR192W RIM2 Mitochondrial pyrimidine nucleotide transporter; imports pyrimidine nucleoside triphosphates and exports pyrimidine nucleoside monophosphates; member of the mitochondrial carrier family Verified chr2:607647-608780 607647-608780 98.6% 178.05 171.79 151.21 136.00 78.74 54.58 174.92 143.60 66.66 0.65 0.58 0.28 -1.11 -0.74 Matched[432]
YBR193C MED8 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation Verified chr2:609077-609748 609077-609748 98.8% 96.42 100.94 120.52 106.96 219.95 129.56 98.68 113.74 174.75 0.36 0.46 0.72 0.62 0.22 Matched[433]
YBR194W Protein proposed to be associated with the nuclear pore complex Uncharacterized chr2:610033-610404 610033-610404 98.4% 101.12 68.32 81.99 71.05 210.43 71.05 84.72 76.52 140.74 0.31 0.31 0.58 0.88 0.68 Matched[434]
YBR195C MSI1 "Subunit of chromatin assembly factor I (CAF-1), negative regulator of the RAS/cAMP pathway via sequestration of Npr1p kinase; localizes to the nucleus and cytoplasm; homologous to human retinoblastoma binding proteins RbAp48 and RbAp46" Verified chr2:610609-611877 610609-611877 98.9% 94.02 108.36 94.02 84.46 49.40 31.87 101.19 89.24 40.64 0.37 0.36 0.17 -1.13 -0.55 Matched[435]
YBR196C PGI1 "Glycolytic enzyme phosphoglucose isomerase, catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate; required for cell cycle progression and completion of the gluconeogenic events of sporulation" Verified chr2:612231-613895 612231-613895 98.6% 6232.48 6080.84 5678.30 5527.87 3363.50 3163.74 6156.66 5603.09 3263.62 22.73 22.74 13.52 -0.78 -1.55 Frag>80[436,437]
YBR196C-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr2:614019-614168 614019-614168 98.6% 47.32 27.04 6.76 40.56 6.76 0.00 37.18 23.66 3.38 0.14 0.10 0.01 -2.81 NaN Covered/w/another[437]
YBR196C-B Putative protein of unknown function; identified by expression profiling and mass spectrometry Uncharacterized chr2:614521-614625 614521-614625 99.0% 125.05 57.72 38.48 48.10 9.62 0.00 91.38 43.29 4.81 0.34 0.18 0.02 -3.17 NaN Covered/w/another[438]
YBR197C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YBR197C is not an essential gene Uncharacterized chr2:615198-615851 615198-615851 98.8% 133.09 191.90 119.16 105.24 91.31 58.81 162.50 112.20 75.06 0.60 0.46 0.31 -0.58 -0.33 Covered/w/another[438]
YBR198C TAF5 "Subunit (90 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification" Verified chr2:616122-618518 616122-618518 99.1% 203.75 195.33 169.65 174.28 129.66 118.29 199.54 171.96 123.97 0.74 0.70 0.51 -0.47 0.11 Covered/w/another[438]
YBR199W KTR4 Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family Verified chr2:618904-620298 618904-620298 98.7% 514.04 651.26 640.37 632.38 859.63 573.57 582.65 636.37 716.60 2.15 2.58 2.97 0.17 0.55 Matched[439]
YBR200W BEM1 "Protein containing SH3-domains, involved in establishing cell polarity and morphogenesis; functions as a scaffold protein for complexes that include Cdc24p, Ste5p, Ste20p, and Rsr1p" Verified chr2:620867-622522 620867-622522 98.7% 149.88 178.63 143.15 157.22 146.21 133.98 164.26 150.19 140.09 0.61 0.61 0.58 -0.10 0.11 Matched[440]
YBR200W-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr2:622978-623142 622978-623142 98.6% 0.00 30.73 6.15 0.00 12.29 6.15 15.36 3.07 9.22 0.06 0.01 0.04 1.58 NaN
YBR201W DER1 "Endoplasmic reticulum membrane protein, required for ER-associated protein degradation of misfolded or unassembled proteins; N- and C- termini protrude into the cytoplasm, has similarity to Dfm1p" Verified chr2:623572-624207 623572-624207 99.0% 96.93 136.65 131.89 119.17 343.22 173.20 116.79 125.53 258.21 0.43 0.51 1.07 1.04 0.76 Matched[441]
YBR201C-A Putative protein of unknown function Uncharacterized chr2:624489-624692 624489-624692 98.9% 54.52 208.18 64.44 74.35 84.26 74.35 131.35 69.39 79.31 0.48 0.28 0.33 0.19 NaN Matched[442]
YBR202W MCM7 "Component of the hexameric MCM complex, which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase" Verified chr2:625767-628304 625767-628304 98.1% 124.14 141.41 118.11 105.66 55.84 48.61 132.77 111.88 52.23 0.49 0.45 0.22 -1.10 -0.41 Matched[443]
YBR203W COS111 "Protein required for resistance to the antifungal drug ciclopirox olamine; not related to the subtelomerically-encoded COS family; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr2:629163-631937 629163-631937 98.8% 26.25 36.82 42.66 58.34 59.79 57.97 31.54 50.50 58.88 0.12 0.20 0.24 0.22 0.41 Matched[444]
YBR204C Serine hydrolase; YBR204C is not an essential gene Uncharacterized chr2:632249-633376 632249-633376 99.2% 190.38 247.58 201.10 213.62 402.20 260.99 218.98 207.36 331.60 0.81 0.84 1.37 0.68 0.76 Matched[445]
YBR205W KTR3 "Putative alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family" Verified chr2:633617-634831 633617-634831 98.8% 568.69 521.23 546.21 565.36 338.88 335.55 544.96 555.79 337.22 2.01 2.26 1.40 -0.72 -0.21 Matched[446]
YBR206W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene KTR3" Dubious chr2:634596-634919 634596-634919 99.3% 758.75 736.98 659.24 730.76 469.55 376.26 747.86 695.00 422.91 2.76 2.82 1.75 -0.72 -0.14 Covered/w/another[446]
YBR207W FTH1 Putative high affinity iron transporter involved in transport of intravacuolar stores of iron; forms complex with Fet5p; expression is regulated by iron; proposed to play indirect role in endocytosis Verified chr2:635141-636538 635141-636538 98.7% 207.18 139.08 220.22 200.66 197.04 168.06 173.13 210.44 182.55 0.64 0.85 0.76 -0.21 0.10 Matched[447]
YBR208C "DUR1,2" "Urea amidolyase, contains both urea carboxylase and allophanate hydrolase activities, degrades urea to CO2 and NH3; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation" Verified chr2:636698-642205 636698-642205 99.0% 147.80 196.39 151.65 203.18 20.72 18.34 172.10 177.41 19.53 0.64 0.72 0.08 -3.18 -1.68 Frag>80[448,449,450]
YBR209W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YBR209W is not an essential gene" Dubious chr2:642578-642895 642578-642895 98.5% 6.38 12.77 6.38 9.58 70.22 22.34 9.58 7.98 46.28 0.04 0.03 0.19 2.54 0.02 Frag<80[450]
YBR210W ERV15 "Protein involved in export of proteins from the endoplasmic reticulum, has similarity to Erv14p" Verified chr2:645545-645973 645545-645973 98.9% 238.07 268.71 245.14 190.93 228.64 120.21 253.39 218.03 174.43 0.94 0.89 0.72 -0.32 -0.29 Matched[452]
YBR211C AME1 "Essential kinetochore protein associated with microtubules and spindle pole bodies; component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p); involved in spindle checkpoint maintenance" Verified chr2:646153-647127 646153-647127 99.2% 94.05 86.82 114.72 75.45 151.93 91.99 90.44 95.09 121.96 0.33 0.39 0.51 0.36 0.18 Matched[453]
YBR212W NGR1 RNA binding protein that negatively regulates growth rate; interacts with the 3' UTR of the mitochondrial porin (POR1) mRNA and enhances its degradation; overexpression impairs mitochondrial function; expressed in stationary phase Verified chr2:647881-649899 647881-649899 98.4% 177.13 182.16 245.06 212.86 310.48 283.31 179.65 228.96 296.89 0.66 0.93 1.23 0.37 0.69 Matched[454]
YBR213W MET8 "Bifunctional dehydrogenase and ferrochelatase, involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis" Verified chr2:650363-651187 650363-651187 98.3% 57.96 40.69 38.23 27.13 25.90 14.80 49.32 32.68 20.35 0.18 0.13 0.08 -0.68 -0.46 Matched[455]
YBR214W SDS24 "One of two S. cerevisiae homologs (Sds23p and Sds24p) of the Schizosaccharomyces pombe Sds23 protein, which genetic studies have implicated in APC/cyclosome regulation; may play an indirect role in fluid-phase endocytosis" Verified chr2:651410-652993 651410-652993 98.8% 222.90 438.77 448.35 464.95 1380.81 1530.26 330.83 456.65 1455.53 1.22 1.85 6.03 1.67 1.85 Frag>80[456,457]
YBR215W HPC2 "Highly charged, basic protein required for normal cell-cycle regulation of histone gene transcription; mutants display strong synthetic defects with subunits of FACT, a complex that allows RNA Pol II to elongate through nucleosomes" Verified chr2:653351-655312 653351-653363,653448-655312 98.7% 145.13 121.93 110.06 127.32 101.97 84.70 133.53 118.69 93.33 0.49 0.48 0.39 -0.35 0.05 Covered/w/another[458]
YBR216C YBP1 "Protein required for oxidation of specific cysteine residues of the transcription factor Yap1p, resulting in the nuclear localization of Yap1p in response to stress" Verified chr2:655571-657595 655571-657595 99.2% 87.09 82.12 78.63 89.58 132.88 116.46 84.61 84.11 124.67 0.31 0.34 0.52 0.57 0.79 Covered/w/another[458]
YBR217W ATG12 "Ubiquitin-like modifier, conjugated via an isopeptide bond to a lysine residue of Atg5p by the E1 enzyme, Atg7p, and the E2 enzyme, Atg10p, a step that is essential for autophagy" Verified chr2:657827-658387 657827-658387 98.7% 81.29 92.13 101.17 81.29 135.49 59.62 86.71 91.23 97.55 0.32 0.37 0.40 0.10 -0.10 Matched[459]
YBR218C PYC2 "Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc1p but differentially regulated; mutations in the human homolog are associated with lactic acidosis" Verified chr2:658702-662244 658702-662244 78.8% 537.46 775.93 527.43 601.55 310.80 405.69 656.69 564.49 358.24 2.42 2.29 1.48 -0.66 -0.35 Frag>80[460,461,462]
YBR219C Putative protein of unknown function; YBR219C is not an essential gene Uncharacterized chr2:662494-663298 662494-662576,662998-663298 98.6% 176.94 174.30 198.06 153.17 71.30 52.82 175.62 175.62 62.06 0.65 0.71 0.26 -1.50 -0.06 Frag<80[461,462]
YBR220C Putative protein of unknown function; YBR220C is not an essential gene Uncharacterized chr2:662990-664672 662990-664672 98.9% 171.91 150.87 165.90 143.66 70.33 54.10 161.39 154.78 62.21 0.60 0.63 0.26 -1.31 -1.22 Matched[463]
YBR221C PDB1 "E1 beta subunit of the pyruvate dehydrogenase (PDH) complex, which is an evolutionarily-conserved multi-protein complex found in mitochondria" Verified chr2:665148-666248 665148-666248 98.8% 1763.85 1928.38 1956.88 1984.45 1412.74 1252.81 1846.12 1970.66 1332.77 6.81 8.00 5.52 -0.56 -0.12 Frag>80[464,465,466]
YBR221W-A Putative protein of unknown function; identified by expression profiling and mass spectrometry Uncharacterized chr2:666533-666637 666533-666637 98.2% 48.48 29.09 19.39 48.48 29.09 48.48 38.79 33.94 38.79 0.14 0.14 0.16 0.19 NaN Matched[466]
YBR222C PCS60 "Peroxisomal AMP-binding protein, localizes to both the peroxisomal peripheral membrane and matrix, expression is highly inducible by oleic acid, similar to E. coli long chain acyl-CoA synthetase" Verified chr2:666715-668346 666715-668346 98.7% 297.45 323.53 299.31 294.96 268.26 252.74 310.49 297.14 260.50 1.15 1.21 1.08 -0.19 0.24 Frag>80[466,467]
YBR223W-A "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps YBR223C; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr2:668716-668835 668716-668835 98.6% 50.70 59.15 42.25 59.15 50.70 59.15 54.93 50.70 54.93 0.20 0.21 0.23 0.12 NaN Covered/w/another[468]
YBR224W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene TDP1" Dubious chr2:670120-670635 670120-670635 99.1% 15.65 15.65 23.47 29.34 21.51 37.16 15.65 26.40 29.34 0.06 0.11 0.12 0.15 1.70 Overlap[468,469]
YBR223C TDP1 "Tyrosyl-DNA Phosphodiesterase I, hydrolyzes 3'-phosphotyrosyl bonds to generate 3'-phosphate DNA and tyrosine, involved in the repair of DNA lesions created by topoisomerase I" Verified chr2:668658-670292 668658-670292 98.9% 50.71 58.75 64.94 59.99 58.75 68.03 54.73 62.46 63.39 0.20 0.25 0.26 0.02 0.87 Matched[468]
YBR225W Putative protein of unknown function; non-essential gene identified in a screen for mutants affected in mannosylphophorylation of cell wall components Uncharacterized chr2:670622-673324 670622-673324 98.9% 63.94 65.06 63.19 64.68 62.81 88.99 64.50 63.94 75.90 0.24 0.26 0.31 0.25 0.88 Covered/w/another[469]
YBR226C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YBR225W" Dubious chr2:673150-673560 673150-673560 99.2% 66.24 76.06 85.87 63.79 115.31 117.77 71.15 74.83 116.54 0.26 0.30 0.48 0.64 0.47 Covered/w/another[469]
YBR227C MCX1 "Mitochondrial ATP-binding protein, possibly a mitochondrial chaperone with non-proteolytic function; similar to bacterial ClpX proteins" Verified chr2:673567-675129 673567-675129 99.3% 179.68 177.10 141.68 150.05 141.68 89.52 178.39 145.87 115.60 0.66 0.59 0.48 -0.34 0.03 Covered/w/another[469]
YBR228W SLX1 "Subunit of a complex, with Slx4p, that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks; function overlaps with that of Sgs1p-Top3p" Verified chr2:675308-676222 675308-676222 98.5% 83.21 104.29 73.22 59.91 106.51 68.79 93.75 66.57 87.65 0.35 0.27 0.36 0.40 0.48 Matched[470]
YBR229C ROT2 "Glucosidase II catalytic subunit required for normal cell wall synthesis; mutations in rot2 suppress tor2 mutations, and are synthetically lethal with rot1 mutations" Verified chr2:676352-679216 676352-679216 98.9% 201.50 223.38 201.50 217.38 188.80 203.27 212.44 209.44 196.03 0.78 0.85 0.81 -0.10 0.35 Matched[471]
YBR230C OM14 Integral mitochondrial outer membrane protein; abundance is decreased in cells grown in glucose relative to other carbon sources; appears to contain 3 alpha-helical transmembrane segments; ORF encodes a 97-basepair intron Verified chr2:679544-680045 679544-679937,680035-680045 98.5% 303.42 318.46 656.98 591.79 4057.26 2011.08 310.94 624.39 3034.17 1.15 2.53 12.57 2.28 1.64 Matched[472]
YBR230W-A Putative protein of unknown function Uncharacterized chr2:680357-680557 680357-680557 97.8% 249.21 345.84 269.55 300.06 971.39 625.56 297.52 284.81 798.47 1.10 1.16 3.31 1.49 NaN Matched[473]
YBR231C SWC5 "Protein of unknown function, component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A" Verified chr2:682174-683085 682174-683085 99.1% 88.54 92.97 97.39 68.62 94.07 111.78 90.75 83.01 102.93 0.34 0.34 0.43 0.31 0.34 Matched[476]
YBR233W PBP2 "RNA binding protein with similarity to mammalian heterogeneous nuclear RNP K protein, involved in the regulation of telomere position effect and telomere length" Verified chr2:683423-684664 683423-684664 98.8% 149.90 128.72 127.09 99.39 141.75 94.50 139.31 113.24 118.13 0.51 0.46 0.49 0.06 0.56 Matched[477]
YBR232C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr2:683368-683727 683368-683727 98.9% 87.09 78.66 98.33 81.47 78.66 50.57 82.87 89.90 64.61 0.31 0.36 0.27 -0.48 0.00 Covered/w/another[477]
YBR233W-A DAD3 "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis" Verified chr2:684972-685256 684972-685256 98.4% 246.06 263.89 274.59 228.23 156.91 78.45 254.98 251.41 117.68 0.94 1.02 0.49 -1.10 -1.17 Matched[478]
YBR234C ARC40 "Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches" Verified chr2:685433-686587 685433-686587 98.9% 674.89 701.15 696.77 621.49 901.60 760.67 688.02 659.13 831.13 2.54 2.68 3.44 0.33 0.64 Matched[479]
YBR235W "Putative ion transporter, similar to mammalian electroneutral Na(+)-(K+)-C1- cotransporter family; YBR235W is not an essential gene" Uncharacterized chr2:686896-690258 686896-690258 98.9% 105.25 109.76 92.02 71.87 64.35 47.51 107.51 81.95 55.93 0.40 0.33 0.23 -0.55 0.04 Frag>80[480]
YBR236C ABD1 "Methyltransferase, catalyzes the transfer of a methyl group from S-adenosylmethionine to the GpppN terminus of capped mRNA" Verified chr2:690378-691688 690378-691688 99.2% 153.02 159.94 142.25 154.56 227.60 168.40 156.48 148.40 198.00 0.58 0.60 0.82 0.42 0.18 Matched[481]
YBR237W PRP5 "RNA helicase in the DEAD-box family, necessary for prespliceosome formation, bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA" Verified chr2:691964-694513 691964-694513 98.5% 88.77 93.55 82.01 72.85 73.25 66.48 91.16 77.43 69.86 0.34 0.31 0.29 -0.15 0.17 Matched[482]
YBR238C Mitochondrial membrane protein with similarity to Rmd9p; not required for respiratory growth but causes a synthetic respiratory defect in combination with rmd9 mutations; transcriptionally up-regulated by TOR; deletion increases life span Verified chr2:695102-697297 695102-697297 98.9% 82.40 96.68 46.96 36.83 4.60 19.80 89.54 41.89 12.20 0.33 0.17 0.05 -1.78 -1.00 Frag>80[483]
YBR239C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YBR239C is not an essential gene Uncharacterized chr2:698349-699938 698349-699938 98.8% 67.49 99.96 51.57 47.12 65.58 41.39 83.73 49.34 53.48 0.31 0.20 0.22 0.12 0.60 Covered/w/another[484]
YBR240C THI2 "Zinc finger protein of the Zn(II)2Cys6 type, probable transcriptional activator of thiamine biosynthetic genes" Verified chr2:700485-701837 700485-701837 98.8% 14.21 18.70 10.47 11.22 24.68 40.39 16.45 10.84 32.53 0.06 0.04 0.13 1.58 1.11 Covered/w/another[484]
YBR241C "Putative transporter, member of the sugar porter family; green fluorescent protein (GFP)-fusion protein localizes to the vacuolar membrane; YBR241C is not an essential gene" Uncharacterized chr2:702584-704050 702584-704050 98.3% 73.54 158.87 72.84 79.78 278.88 296.92 116.20 76.31 287.90 0.43 0.31 1.19 1.92 1.93 Matched[485]
YBR242W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YBR242W is not an essential gene Uncharacterized chr2:704665-705381 704665-705381 98.6% 237.74 185.38 192.45 165.57 70.75 63.68 211.56 179.01 67.22 0.78 0.73 0.28 -1.41 -1.42 Matched[486]
YBR243C ALG7 "UDP-N-acetyl-glucosamine-1-P transferase, transfers Glc-Nac-P from UDP-GlcNac to Dol-P in the ER in the first step of the dolichol pathway of protein asparagine-linked glycosylation; inhibited by tunicamycin" Verified chr2:705442-706788 705442-706788 98.8% 226.10 177.28 226.85 195.31 144.23 114.93 201.69 211.08 129.58 0.74 0.86 0.54 -0.70 -0.51 Matched[487]
YBR244W GPX2 Phospholipid hydroperoxide glutathione peroxidase induced by glucose starvation that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress Verified chr2:707523-708011 707523-708011 98.4% 700.44 66.51 544.56 228.63 232.79 91.45 383.48 386.59 162.12 1.42 1.57 0.67 -1.25 -1.37 Matched[488]
YBR245C ISW1 "Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes; ATPase that forms a complex with Ioc2p and Ioc4p to regulate transcription elongation, and a complex with Ioc3p to repress transcription initiation" Verified chr2:708145-711534 708145-711534 99.1% 210.47 151.83 186.06 165.82 100.32 105.68 181.15 175.94 103.00 0.67 0.71 0.43 -0.77 -0.42 Frag>80[489]
YBR246W Putative protein of unknown function; deletion results in a weak carboxypeptidase Y missorting/secretion phenotype; YBR246W is not an essential gene Uncharacterized chr2:711586-712749 711586-712749 98.9% 233.63 184.13 204.97 179.79 163.28 127.67 208.88 192.38 145.48 0.77 0.78 0.60 -0.40 0.01 Matched[490]
YBR247C ENP1 "Protein associated with U3 and U14 snoRNAs, required for pre-rRNA processing and 40S ribosomal subunit synthesis; localized in the nucleus and concentrated in the nucleolus" Verified chr2:712999-714450 712999-714450 99.1% 174.36 102.12 79.19 73.63 17.37 4.17 138.24 76.41 10.77 0.51 0.31 0.04 -2.83 -2.91 Matched[491]
YBR248C HIS7 "Imidazole glycerol phosphate synthase (glutamine amidotransferase:cyclase), catalyzes the fifth and sixth steps of histidine biosynthesis and also produces 5-aminoimidazole-4-carboxamide ribotide (AICAR), a purine precursor" Verified chr2:714802-716460 714802-716460 99.2% 298.43 373.20 298.43 274.12 79.62 78.41 335.82 286.28 79.02 1.24 1.16 0.33 -1.86 -1.33 Frag>80[492,493,494]
YBR249C ARO4 "3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by tyrosine or high concentrations of phenylalanine or tryptophan" Verified chr2:716877-717989 716877-717989 98.7% 1437.56 1575.86 1287.44 1074.53 263.86 176.51 1506.71 1180.98 220.18 5.56 4.79 0.91 -2.42 -1.91 Frag>80[494,495,496]
YBR250W SPO23 Protein of unknown function; associates with meiosis-specific protein Spo1p Verified chr2:719028-720599 719028-720599 99.1% 7.06 8.35 3.21 7.06 8.35 12.84 7.71 5.14 10.60 0.03 0.02 0.04 1.04 0.34
YBR251W MRPS5 Mitochondrial ribosomal protein of the small subunit Verified chr2:721385-722308 721385-722308 98.5% 229.58 231.77 262.53 209.80 259.23 246.05 230.67 236.17 252.64 0.85 0.96 1.05 0.10 0.24 Covered/w/another[497]
YBR252W DUT1 "dUTPase, catalyzes hydrolysis of dUTP to dUMP and PPi, thereby preventing incorporation of uracil into DNA during replication; critical for the maintenance of genetic stability" Verified chr2:722606-723049 722606-723049 98.6% 440.72 347.10 411.04 395.05 205.52 155.28 393.91 403.04 180.40 1.45 1.64 0.75 -1.16 -1.35 Covered/w/another[497]
YBR253W SRB6 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation Verified chr2:723265-723630 723265-723630 98.4% 405.32 421.98 366.45 327.59 433.08 249.86 413.65 347.02 341.47 1.53 1.41 1.41 -0.02 -0.13 Covered/w/another[497]
YBR254C TRS20 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; mutations in the human homolog cause the spondyloepiphyseal dysplasia tarda (SEDL) disorder Verified chr2:723731-724258 723731-724258 99.3% 162.14 123.99 123.99 120.17 116.36 53.41 143.06 122.08 84.88 0.53 0.50 0.35 -0.52 -0.86 Covered/w/another[497]
YBR255W "Protein of unknown function, required for normal growth rate at 15 degrees C; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" Uncharacterized chr2:724451-726535 724451-726535 98.6% 86.63 94.90 79.33 76.41 67.16 62.29 90.76 77.87 64.73 0.34 0.32 0.27 -0.27 0.04 Matched[498]
YBR255C-A Putative protein of unknown function; identified by sequence comparison with hemiascomycetous yeast species Uncharacterized chr2:726613-727069 726613-726912,727007-727069 98.9% 264.65 231.22 234.01 186.65 197.79 64.07 247.94 210.33 130.93 0.92 0.85 0.54 -0.68 -0.54 Matched[499]
YBR256C RIB5 Riboflavin synthase; catalyzes the last step of the riboflavin biosynthesis pathway Verified chr2:727381-728097 727381-728097 99.3% 508.19 905.47 512.40 452.04 1010.76 536.27 706.83 482.22 773.51 2.61 1.96 3.20 0.68 -0.14 Frag>80[499,500,501]
YBR257W POP4 "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; binds to the RPR1 RNA subunit in Rnase P" Verified chr2:728880-729719 728880-729719 98.8% 99.97 98.77 95.15 66.25 71.06 36.13 99.37 80.70 53.60 0.37 0.33 0.22 -0.59 -1.10 Matched[502]
YBR258C SHG1 "Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres" Verified chr2:729729-730157 729729-730157 99.6% 126.37 138.07 145.09 109.98 163.81 88.92 132.22 127.54 126.37 0.49 0.52 0.52 -0.01 -0.40 Matched[503]
YBR259W Putative protein of unknown function; YBR259W is not an essential gene Uncharacterized chr2:730382-732448 730382-732448 98.9% 60.64 55.75 47.92 47.43 39.61 25.43 58.19 47.68 32.52 0.21 0.19 0.13 -0.55 -0.36 Matched[504]
YBR260C RGD1 "GTPase-activating protein (RhoGAP) for Rho3p and Rho4p, possibly involved in control of actin cytoskeleton organization" Verified chr2:732634-734634 732634-734634 99.0% 147.90 159.00 129.72 145.37 131.74 132.25 153.45 137.55 132.00 0.57 0.56 0.55 -0.06 0.42 Matched[505]
YBR261C Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YBR261C is not an essential gene Uncharacterized chr2:734827-735525 734827-735525 99.0% 249.95 218.17 210.94 215.28 179.16 150.26 234.06 213.11 164.71 0.86 0.87 0.68 -0.37 -0.14 Matched[506]
YBR262C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr2:735715-736035 735715-736035 99.2% 392.57 389.43 364.30 414.55 474.22 279.51 391.00 389.43 376.86 1.44 1.58 1.56 -0.05 -0.61 Matched[507]
YBR263W SHM1 "Mitochondrial serine hydroxymethyltransferase, involved in one-carbon metabolism" Verified chr2:736259-737731 736259-737731 98.7% 658.95 566.78 593.60 588.79 255.88 304.02 612.86 591.20 279.95 2.26 2.40 1.16 -1.08 -0.30 Matched[508]
YBR264C YPT10 GTP binding protein that contains the PEST signal sequence specific for proteolytic enzymes; may be involved in vesicular transport; overexpression leads to accumulation of Golgi-like cisternae with budding vesicles Verified chr2:737765-738364 737765-738364 99.4% 219.75 213.04 219.75 186.20 228.14 149.30 216.40 202.98 188.72 0.80 0.82 0.78 -0.11 -0.16 Matched[509]
YBR265W TSC10 "3-ketosphinganine reductase, catalyzes the second step in phytosphingosine synthesis, essential for growth in the absence of exogenous dihydrosphingosine or phytosphingosine, member of short chain dehydrogenase/reductase protein family" Verified chr2:738577-739539 738577-739539 98.5% 319.41 360.52 343.66 310.98 176.04 156.02 339.97 327.32 166.03 1.25 1.33 0.69 -0.98 -0.56 Matched[510]
YBR267W REI1 "Cytoplasmic pre-60S factor; required for the correct recycling of shuttling factors Alb1, Arx1 and Tif6 at the end of the ribosomal large subunit biogenesis; involved in bud growth in the mitotic signaling network" Verified chr2:739836-741017 739836-741017 98.2% 171.39 123.16 106.80 81.82 12.06 6.03 147.28 94.31 9.04 0.54 0.38 0.04 -3.38 0.92 Matched[511]
YBR266C SLM6 Protein with a potential role in actin cytoskeleton organization; gene exhibits synthetic genetic interaction with MSS4 encoding phosphatidylinositol 4-phosphate kinase Dubious chr2:739931-740383 739931-740383 98.2% 150.58 130.35 80.91 80.91 6.74 8.99 140.46 80.91 7.87 0.52 0.33 0.03 -3.36 -0.03 Matched[511]
YBR268W MRPL37 Mitochondrial ribosomal protein of the large subunit Verified chr2:741294-741611 741294-741611 98.2% 506.21 438.93 515.82 410.09 429.32 272.33 472.57 462.96 350.82 1.74 1.88 1.45 -0.40 -1.19 Matched[512]
YBR269C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr2:742155-742571 742155-742571 98.9% 186.70 213.38 266.72 257.02 729.84 497.07 200.04 261.87 613.46 0.74 1.06 2.54 1.23 1.07 Matched[513]
YBR270C Hypothetical protein Uncharacterized chr2:742756-744393 742756-744393 99.0% 46.86 66.59 45.01 29.60 36.99 23.43 56.72 37.30 30.21 0.21 0.15 0.13 -0.30 -0.15 Matched[514]
YBR271W Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YBR271W is not as essential gene Uncharacterized chr2:744847-746106 744847-746106 98.6% 82.94 57.98 48.31 34.63 16.10 15.30 70.46 41.47 15.70 0.26 0.17 0.07 -1.40 -1.81 Matched[515]
YBR272C HSM3 "Protein of unknown function, involved in DNA mismatch repair during slow growth; has weak similarity to Msh1p" Verified chr2:746356-747798 746356-747798 99.3% 88.61 101.87 101.87 90.01 169.54 133.96 95.24 95.94 151.75 0.35 0.39 0.63 0.66 0.66 Matched[516]
YBR273C UBX7 UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p Verified chr2:748056-749366 748056-749366 99.1% 167.88 190.21 160.17 166.34 418.15 320.35 179.04 163.25 369.25 0.66 0.66 1.53 1.18 1.32 Frag>80[517,518]
YBR274W CHK1 "Serine/threonine kinase and DNA damage checkpoint effector, mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase" Verified chr2:749589-751172 749589-751172 98.9% 109.19 121.33 95.78 94.51 138.57 118.77 115.26 95.14 128.67 0.43 0.39 0.53 0.44 0.41 Matched[519]
YBR275C RIF1 Protein that binds to the Rap1p C-terminus and acts synergistically with Rif2p to help control telomere length and establish telomeric silencing; deletion results in telomere elongation Verified chr2:751351-757101 751351-757101 99.3% 78.46 61.65 54.82 51.31 17.69 18.21 70.05 53.07 17.95 0.26 0.22 0.07 -1.56 -0.96 Frag<80[520]
YBR276C PPS1 "Protein phosphatase with specificity for serine, threonine, and tyrosine residues; has a role in the DNA synthesis phase of the cell cycle" Verified chr2:757616-760039 757616-760039 99.1% 254.32 205.62 221.44 191.47 123.62 136.94 229.97 206.46 130.28 0.85 0.84 0.54 -0.66 -0.37 Covered/w/another[521]
YBR278W DPB3 "Third-largest subunit of DNA polymerase II (DNA polymerase epsilon), required to maintain fidelity of chromosomal replication and also for inheritance of telomeric silencing; mRNA abundance peaks at the G1/S boundary of the cell cycle" Verified chr2:760290-760895 760290-760895 98.4% 206.20 154.23 172.67 129.09 234.70 114.00 180.22 150.88 174.35 0.67 0.61 0.72 0.21 -0.07 Covered/w/another[521]
YBR277C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YBR278W" Dubious chr2:760211-760612 760211-760612 98.6% 133.74 100.94 105.98 121.12 138.79 88.32 117.34 113.55 113.55 0.43 0.46 0.47 0.00 0.06 Covered/w/another[521]
YBR279W PAF1 RNAP II-associated protein; defines large complex biochemically and functionally distinct from the Srb-Mediator form of Pol II holoenzyme; required for full expression of a subset of cell cycle-regulated genes; homolog of human PD2/hPAF1 Verified chr2:761253-762590 761253-762590 98.3% 342.98 306.47 337.65 337.65 574.92 393.93 324.73 337.65 484.43 1.20 1.37 2.01 0.52 0.90 Matched[522]
YBR280C SAF1 F-Box protein involved in proteasome-dependent degradation of Aah1p during entry of cells into quiescence; interacts with Skp1 Verified chr2:762780-764693 762780-764693 99.1% 51.67 51.14 64.32 51.67 284.18 238.84 51.41 58.00 261.51 0.19 0.24 1.08 2.17 1.76 Matched[523]
YBR281C DUG2 Probable di- and tri-peptidase; forms a complex with Dug1p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p) Verified chr2:764966-767602 764966-767602 99.2% 93.28 86.01 78.37 64.22 52.75 56.20 89.64 71.30 54.48 0.33 0.29 0.23 -0.39 0.13 Matched[524]
YBR282W MRPL27 Mitochondrial ribosomal protein of the large subunit Verified chr2:768236-768676 768236-768676 98.4% 327.31 315.79 396.47 308.87 523.24 304.26 321.55 352.67 413.75 1.19 1.43 1.71 0.23 0.13 Matched[525]
YBR283C SSH1 Subunit of the Ssh1 translocon complex; Sec61p homolog involved in co-translational pathway of protein translocation; not essential Verified chr2:768939-770411 768939-770411 98.9% 1248.88 1103.33 1180.91 1132.17 652.25 590.46 1176.11 1156.54 621.35 4.34 4.69 2.57 -0.90 -0.28 Matched[526]
YBR284W Putative protein of unknown function; YBR284W is not an essential gene; null mutant exhibits decreased resistance to rapamycin and wortmannin Uncharacterized chr2:771235-773628 771235-773628 98.9% 19.42 18.58 12.67 11.40 48.56 28.71 19.00 12.03 38.63 0.07 0.05 0.16 1.68 1.72 Frag<80[527]
YBR285W Putative protein of unknown function; YBR285W is not an essential gene and deletion of YBR285W leads to poor growth on glucose-minimal medium at 15C Uncharacterized chr2:773918-774352 773918-774352 98.8% 39.57 93.11 100.10 125.70 1652.76 1014.94 66.34 112.90 1333.85 0.24 0.46 5.53 3.56 3.10 Matched[528]
YBR286W APE3 "Vacuolar aminopeptidase Y, processed to mature form by Prb1p" Verified chr2:774696-776309 774696-776309 98.8% 2619.65 3875.88 2941.23 3112.36 3919.14 4243.22 3247.77 3026.80 4081.18 11.99 12.29 16.91 0.43 0.63 Matched[529]
YBR287W Protein of unknown function; mutation results in a zinc sensitive phenotype Uncharacterized chr2:776567-777850 776567-777850 99.0% 289.47 337.45 354.76 358.69 821.21 762.22 313.46 356.72 791.71 1.16 1.45 3.28 1.15 1.39 Matched[530]
YBR288C APM3 Mu3-like subunit of the clathrin associated protein complex (AP-3); functions in transport of alkaline phosphatase to the vacuole via the alternate pathway Verified chr2:778008-779459 778008-779459 99.2% 228.43 188.16 195.79 162.47 154.14 102.06 208.29 179.13 128.10 0.77 0.73 0.53 -0.48 -0.48 Matched[531]
YBR289W SNF5 Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf6p Verified chr2:779663-782380 779663-782380 95.4% 97.58 91.41 96.04 93.34 55.16 72.51 94.50 94.69 63.83 0.35 0.38 0.26 -0.57 0.57 Matched[532]
YBR290W BSD2 "Heavy metal ion homeostasis protein, facilitates trafficking of Smf1p and Smf2p metal transporters to the vacuole where they are degraded, controls metal ion transport, prevents metal hyperaccumulation, functions in copper detoxification" Verified chr2:782587-783552 782587-783552 98.6% 155.43 193.24 173.29 191.14 442.15 253.11 174.34 182.22 347.63 0.64 0.74 1.44 0.93 0.76 Matched[533]
YBR291C CTP1 "Mitochondrial inner membrane citrate transporter, member of the mitochondrial carrier family" Verified chr2:783669-784568 783669-784568 99.0% 106.61 117.83 93.15 58.36 68.46 31.42 112.22 75.75 49.94 0.41 0.31 0.21 -0.60 -0.40 Matched[534]
YBR292C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YBR292C is not an essential gene" Dubious chr2:784698-785069 784698-785069 98.8% 16.33 2.72 10.89 5.44 5.44 0.00 9.52 8.16 2.72 0.04 0.03 0.01 -1.58 -0.26 Overlap[535]
YBR293W VBA2 Permease of basic amino acids in the vacuolar membrane Verified chr2:787001-788425 787001-788425 99.1% 88.52 89.93 66.56 62.32 57.36 48.86 89.22 64.44 53.11 0.33 0.26 0.22 -0.28 -0.05 Matched[536]
YBR294W SUL1 "High affinity sulfate permease; sulfate uptake is mediated by specific sulfate transporters Sul1p and Sul2p, which control the concentration of endogenous activated sulfate intermediates" Verified chr2:789230-791809 789230-791809 98.9% 44.70 44.70 36.86 29.41 37.64 29.80 44.70 33.13 33.72 0.17 0.13 0.14 0.03 1.40 Matched[537]
YBR295W PCA1 Cadmium transporting P-type ATPase; may also have a role in copper and iron homeostasis; S288C and most other lab strains contain a G970R mutation which eliminates normal cadmium transport function Verified chr2:792843-796493 792843-796493 98.7% 44.11 51.05 30.52 35.79 24.97 33.57 47.58 33.15 29.27 0.18 0.13 0.12 -0.18 -0.15 Frag<80[538]
YBR296C PHO89 "Na+/Pi cotransporter, active in early growth phase; similar to phosphate transporters of Neurospora crassa; transcription regulated by inorganic phosphate concentrations and Pho4p" Verified chr2:796792-798516 796792-798516 98.9% 129.60 31.67 208.76 81.51 22.28 7.62 80.63 145.14 14.95 0.30 0.59 0.06 -3.28 -2.85 Matched[539]
YBR296C-A "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr2:800117-800236 800117-800236 98.5% 8.46 0.00 16.91 0.00 0.00 0.00 4.23 8.46 0.00 0.02 0.03 0.00 -Inf NaN
YBR297W MAL33 "MAL-activator protein, part of complex locus MAL3; nonfunctional in genomic reference strain S288C" Verified chr2:800517-801923 800517-801923 88.0% 53.31 77.54 95.31 87.23 51.69 21.00 65.42 91.27 36.35 0.24 0.37 0.15 -1.33 -1.21 Matched[540]
YBR298C MAL31 "Maltose permease, high-affinity maltose transporter (alpha-glucoside transporter); encoded in the MAL3 complex locus; member of the 12 transmembrane domain superfamily of sugar transporters; functional in genomic reference strain S288C" Verified chr2:802625-804469 802625-804469 99.0% 61.86 73.91 74.45 64.05 91.43 49.27 67.88 69.25 70.35 0.25 0.28 0.29 0.02 -0.31 Matched[541]
YBR298C-A "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr2:805029-805250 805029-805250 7.0% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN NaN
YBR299W MAL32 "Maltase (alpha-D-glucosidase), inducible protein involved in maltose catabolism; encoded in the MAL3 complex locus; functional in genomic reference strain S288C" Verified chr2:805345-807099 805345-807099 3.6% 0.00 0.00 15.77 0.00 31.54 0.00 0.00 7.88 15.77 0.00 0.03 0.07 1.00 -0.06
YBR301W DAN3 "Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth" Verified chr2:809051-809413 809051-809413 3.1% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.70
YBR300C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YBR301W; YBR300C is not an essential gene" Dubious chr2:808594-809091 808594-809091 9.8% 0.00 0.00 0.00 0.00 40.96 0.00 0.00 0.00 20.48 0.00 0.00 0.08 Inf -0.29
YBR302C COS2 "Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" Verified chr2:810334-811473 810334-811473 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.14
YCL076W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr3:1392-2135 1392-2135 97.7% 1.38 0.00 0.00 0.00 0.00 0.00 0.69 0.00 0.00 0.00 0.00 0.00 NaN -0.01
YCL073C Protein of unconfirmed function; displays a topology characteristic of the Major Facilitators Superfamily of membrane proteins; coding sequence 98% identical to that of YKR106W Uncharacterized chr3:6479-8326 6479-8326 7.4% 0.00 7.30 0.00 7.30 0.00 0.00 3.65 3.65 0.00 0.01 0.01 0.00 -Inf 0.66
YCL069W VBA3 Permease of basic amino acids in the vacuolar membrane Verified chr3:9706-11082 9706-11082 4.0% 0.00 0.00 0.00 0.00 0.00 36.53 0.00 0.00 18.26 0.00 0.00 0.08 Inf -0.01
YCL068C Putative protein of unknown function Uncharacterized chr3:11503-12285 11503-12285 1.8% 0.00 0.00 0.00 0.00 0.00 69.97 0.00 0.00 34.99 0.00 0.00 0.14 Inf 1.20
YCL067C HMLALPHA2 Silenced copy of ALPHA2 at HML; homeobox-domain protein that associates with Mcm1p in haploid cells to repress a-specific gene expression and interacts with a1p in diploid cells to repress haploid-specific gene expression Verified|silenced_gene chr3:12386-13018 12386-13018 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.19
YCL066W HMLALPHA1 "Silenced copy of ALPHA1 at HML, encoding a transcriptional coactivator involved in the regulation of mating-type alpha-specific gene expression" Verified|silenced_gene chr3:13282-13809 13282-13809 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.47
YCL065W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps HMLALPHA1" Dubious chr3:13751-14119 13751-14119 35.4% 0.00 7.65 0.00 0.00 0.00 0.00 3.83 0.00 0.00 0.01 0.00 0.00 NaN 0.28
YCL064C CHA1 "Catabolic L-serine (L-threonine) deaminase, catalyzes the degradation of both L-serine and L-threonine; required to use serine or threonine as the sole nitrogen source, transcriptionally induced by serine and threonine" Verified chr3:15798-16880 15798-16880 99.1% 141.68 76.43 164.98 243.28 4043.50 2679.82 109.06 204.13 3361.66 0.40 0.83 13.93 4.04 3.27 Matched[543]
YCL063W VAC17 Protein involved in vacuole inheritance; acts as a vacuole-specific receptor for myosin Myo2p Verified chr3:17290-18561 17290-18561 98.9% 134.30 123.18 116.82 91.39 116.03 85.03 128.74 104.11 100.53 0.48 0.42 0.42 -0.05 -0.19 Covered/w/another[544]
YCL061C MRC1 "S-phase checkpoint protein found at replication forks, required for DNA replication; also required for Rad53p activation during DNA replication stress, where it forms a replication-pausing complex with Tof1p and is phosphorylated by Mec1p" Verified chr3:18816-22106 18816-22106 99.3% 123.60 104.33 96.99 92.09 44.67 63.33 113.97 94.54 54.00 0.42 0.38 0.22 -0.81 -0.44 Covered/w/another[544]
YCL059C KRR1 Essential nucleolar protein required for the synthesis of 18S rRNA and for the assembly of 40S ribosomal subunit Verified chr3:22429-23379 22429-23379 99.3% 578.08 291.16 434.09 354.69 73.05 54.00 434.62 394.39 63.53 1.60 1.60 0.26 -2.63 -2.24 Covered/w/another[544]
YCL058W-A Protein of unknown function; identified by homology to Ashbya gossypii Uncharacterized chr3:23584-23925 23584-23925 97.7% 173.59 149.64 137.67 101.76 80.81 41.90 161.62 119.72 61.35 0.60 0.49 0.25 -0.96 NaN Matched[545]
YCL058C FYV5 "Protein of unknown function, required for survival upon exposure to K1 killer toxin; involved in ion homeostasis" Dubious chr3:23523-23981 23523-23981 97.8% 231.60 195.97 180.38 149.21 142.53 69.04 213.79 164.80 105.78 0.79 0.67 0.44 -0.64 -0.02 Matched[545]
YCL057C-A "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr3:24032-24325 24032-24325 98.6% 980.16 938.74 914.58 997.41 1394.31 997.41 959.45 956.00 1195.86 3.54 3.88 4.95 0.32 0.00 Matched[546]
YCL057W PRD1 "Zinc metalloendopeptidase, found in the cytoplasm and intermembrane space of mitochondria; with Cym1p, involved in degradation of mitochondrial proteins and of presequence peptides cleaved from imported proteins" Verified chr3:24768-26906 24768-26906 98.9% 337.54 359.76 311.54 344.63 416.96 375.36 348.65 328.09 396.16 1.29 1.33 1.64 0.27 0.41 Matched[547]
YCL056C Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern Uncharacterized chr3:26925-27359 26925-27359 99.5% 224.10 265.69 198.69 205.62 288.79 184.83 244.90 202.16 236.81 0.90 0.82 0.98 0.23 -0.37 Matched[548]
YCL055W KAR4 "Transcription factor required for gene regulation in repsonse to pheromones; also required during meiosis; exists in two forms, a slower-migrating form more abundant during vegetative growth and a faster-migrating form induced by pheromone" Verified chr3:27929-28936 27929-28936 98.8% 151.68 150.68 206.93 193.87 173.78 68.31 151.18 200.40 121.04 0.56 0.81 0.50 -0.73 -0.90 Covered[549]
YCL054W SPB1 "AdoMet-dependent methyltransferase involved in rRNA processing and 60S ribosomal subunit maturation; methylates G2922 in the tRNA docking site of the large subunit rRNA and in the absence of snR52, U2921; suppressor of PAB1 mutants" Verified chr3:31449-33974 31449-33974 98.3% 301.58 147.37 168.71 136.90 17.31 6.04 224.47 152.80 11.68 0.83 0.62 0.05 -3.71 -1.99 Matched[551]
YCL052C PBN1 "Essential component of glycosylphosphatidylinositol-mannosyltransferase I, required for the autocatalytic post-translational processing of the protease B precursor Prb1p, localizes to ER in lumenal orientation; homolog of mammalian PIG-X" Verified chr3:34143-35393 34143-35393 99.1% 178.27 224.25 190.37 225.86 447.69 354.92 201.26 208.11 401.30 0.74 0.84 1.66 0.95 0.75 Matched[552]
YCL051W LRE1 Protein involved in control of cell wall structure and stress response; inhibits Cbk1p protein kinase activity; overproduction confers resistance to cell-wall degrading enzymes Verified chr3:35865-37616 35865-37616 98.6% 125.02 127.33 133.12 129.07 203.73 178.85 126.18 131.10 191.29 0.47 0.53 0.79 0.55 0.90 Matched[553]
YCL050C APA1 "Diadenosine 5',5''-P1,P4-tetraphosphate phosphorylase I (AP4A phosphorylase), involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; has similarity to Apa2p" Verified chr3:37836-38801 37836-38801 98.9% 958.70 1061.27 900.09 877.07 3126.25 2553.75 1009.99 888.58 2840.00 3.73 3.61 11.77 1.68 1.90 Matched[554]
YCL049C Protein of unknown function; localizes to membrane fraction; YCL049C is not an essential gene; Uncharacterized chr3:39786-40724 39786-40724 98.8% 241.42 335.19 225.26 188.61 220.94 120.71 288.31 206.93 170.83 1.06 0.84 0.71 -0.28 -0.92 Matched[556]
YCL048W-A Putative protein of unknown function Uncharacterized chr3:41488-41727 41488-41727 98.9% 25.29 16.86 8.43 16.86 573.13 303.42 21.07 12.64 438.28 0.08 0.05 1.82 5.12 NaN Matched[557]
YCL048W SPS22 "Protein of unknown function, redundant with Sps2p for the organization of the beta-glucan layer of the spore wall" Verified chr3:42165-43556 42165-43556 98.9% 1.45 6.54 5.81 8.72 3.63 8.72 4.00 7.26 6.17 0.01 0.03 0.03 -0.23 -0.25 Frag<80[557,558]
YCL047C Putative protein of unknown function Uncharacterized chr3:43661-44437 43661-44437 99.0% 107.89 139.08 110.49 123.48 386.05 236.57 123.48 116.98 311.31 0.46 0.47 1.29 1.41 1.26 Matched[559]
YCL046W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YCL045C" Dubious chr3:46640-46963 46640-46963 98.4% 185.10 150.59 125.49 156.86 69.02 90.98 167.84 141.18 80.00 0.62 0.57 0.33 -0.82 0.26 Covered/w/another[560]
YCL045C Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the ER; interacts with Gal80p; YCL045C is not an essential gene Uncharacterized chr3:44623-46905 44623-46905 99.0% 374.86 366.90 360.26 351.85 216.42 226.60 370.88 356.05 221.51 1.37 1.45 0.92 -0.68 -0.06 Matched[560]
YCL044C MGR1 "Subunit, with Yme1p, of the mitochondrial inner membrane i-AAA protease complex, which is responsible for degradation of unfolded or misfolded mitochondrial gene products; required for growth of cells lacking the mitochondrial genome" Verified chr3:47111-48364 47111-48364 98.2% 104.72 106.35 125.83 111.22 243.54 267.08 105.53 118.52 255.31 0.39 0.48 1.06 1.11 1.47 Matched[561]
YCL043C PDI1 "Protein disulfide isomerase, multifunctional protein resident in the endoplasmic reticulum lumen, essential for the formation of disulfide bonds in secretory and cell-surface proteins, unscrambles non-native disulfide bonds" Verified chr3:48653-50221 48653-50221 98.4% 2466.75 2462.22 2539.26 2278.35 3237.85 2835.79 2464.49 2408.81 3036.82 9.10 9.78 12.58 0.33 0.65 Frag>80[562,563,564]
YCL042W Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm Uncharacterized chr3:50584-50943 50584-50943 98.6% 349.25 568.95 785.82 949.18 2157.49 2174.39 459.10 867.50 2165.94 1.69 3.52 8.97 1.32 2.62 Frag<80[564]
YCL041C Hypothetical protein; open reading frame overlaps 5' end of essential PDI1 gene encoding protein disulfide isomerase Dubious chr3:50133-50627 50133-50627 96.1% 384.82 428.98 454.22 386.93 593.01 630.86 406.90 420.57 611.93 1.50 1.71 2.54 0.54 2.47 Frag<80[564]
YCL040W GLK1 "Glucokinase, catalyzes the phosphorylation of glucose at C6 in the first irreversible step of glucose metabolism; one of three glucose phosphorylating enzymes; expression regulated by non-fermentable carbon sources" Verified chr3:50838-52340 50838-52340 98.5% 1417.05 2838.83 3288.88 3589.59 9691.63 7840.75 2127.94 3439.24 8766.19 7.86 13.96 36.32 1.35 1.07 Matched[565]
YCL039W GID7 "Protein of unknown function, involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains six WD40 repeats; computational analysis suggests that Gid7p and Moh1p have similar functions" Verified chr3:52645-54882 52645-54882 98.8% 101.74 146.51 121.18 127.52 163.69 116.21 124.12 124.35 139.95 0.46 0.50 0.58 0.17 0.07 Covered/w/another[566]
YCL038C ATG22 "Protein required for the breakdown of autophagic vesicles in the vacuole during autophagy, putative integral membrane protein that localizes to vacuolar membranes and punctate structures attached to the vacuole" Verified chr3:54941-56527 54941-56527 98.9% 156.06 385.38 135.04 136.32 137.59 114.02 270.72 135.68 125.81 1.00 0.55 0.52 -0.11 -0.27 Covered/w/another[566]
YCL037C SRO9 "Cytoplasmic RNA-binding protein that associates with translating ribosomes; involved in heme regulation of Hap1p as a component of the HMC complex, also involved in the organization of actin filaments; contains a La motif" Verified chr3:57374-58678 57374-58678 98.6% 640.48 515.34 458.59 387.86 52.85 45.08 577.91 423.23 48.97 2.13 1.72 0.20 -3.11 -2.49 Covered/w/another[566]
YCL036W GFD2 "Protein of unknown function, identified as a high-copy suppressor of a dbp5 mutation" Verified chr3:59026-60726 59026-60726 98.1% 46.13 44.93 23.96 19.77 9.58 12.58 45.53 21.87 11.08 0.17 0.09 0.05 -0.98 -0.60 Frag<80[567,568]
YCL035C GRX1 Hydroperoxide and superoxide-radical responsive heat-stable glutathione-dependent disulfide oxidoreductase with active site cysteine pair; protects cells from oxidative damage Verified chr3:60841-61173 60841-61173 99.1% 1260.61 1793.94 1169.70 1445.45 7527.27 5457.58 1527.27 1307.58 6492.42 5.64 5.31 26.90 2.31 1.42 Matched[568]
YCL034W LSB5 "Protein of unknown function; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization" Verified chr3:61658-62722 61658-62722 98.2% 250.52 253.39 360.48 284.94 547.89 350.92 251.95 322.71 449.40 0.93 1.31 1.86 0.48 0.36 Matched[569]
YCL033C Putative protein-methionine-R-oxide reductase; involved in response to oxidative stress; similar to mouse Sepx1p and fly SelRp; YCL033C is not an essential gene Uncharacterized chr3:62776-63282 62776-63282 99.0% 157.40 201.23 201.23 183.30 402.46 280.92 179.31 192.26 341.69 0.66 0.78 1.42 0.83 0.46 Matched[570]
YCL032W STE50 "Protein involved in mating response, invasive/filamentous growth, and osmotolerance, acts as an adaptor that links G protein-associated Cdc42p-Ste20p complex to the effector Ste11p to modulate signal transduction" Verified chr3:63441-64481 63441-64481 98.5% 114.14 128.78 106.34 120.97 127.80 80.97 121.46 113.65 104.39 0.45 0.46 0.43 -0.12 0.28 Matched[571]
YCL031C RRP7 Essential protein involved in rRNA processing and ribosome biogenesis Verified chr3:64675-65568 64675-65568 99.3% 474.21 344.68 396.49 332.29 307.50 200.50 409.44 364.39 254.00 1.51 1.48 1.05 -0.52 -0.53 Matched[572]
YCL030C HIS4 "Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase, phosphoribosyl-AMP cyclohydrolase, and histidinol dehydrogenase activities; catalyzes the second, third, ninth and tenth steps in histidine biosynthesis" Verified chr3:65934-68333 65934-68333 98.9% 938.39 2060.82 951.02 1043.26 357.16 426.65 1499.61 997.14 391.91 5.54 4.05 1.62 -1.35 -0.65 Frag>80[573,574]
YCL029C BIK1 "Microtubule-associated protein, component of the interface between microtubules and kinetochore, involved in sister chromatid separation; essential in polyploid cells but not in haploid or diploid cells; ortholog of mammalian CLIP-170" Verified chr3:68599-69921 68599-69921 99.2% 107.46 76.21 77.74 83.07 56.40 47.25 91.84 80.40 51.82 0.34 0.33 0.21 -0.63 -0.16 Matched[575]
YCL028W RNQ1 "[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate" Verified chr3:70150-71367 70150-71367 98.4% 456.50 479.03 448.15 421.45 344.67 341.33 467.77 434.80 343.00 1.73 1.76 1.42 -0.34 0.23 Matched[576]
YCL027W FUS1 "Membrane protein localized to the shmoo tip, required for cell fusion; expression regulated by mating pheromone; proposed to coordinate signaling, fusion, and polarization events required for fusion; potential Cdc28p substrate" Verified chr3:71803-73341 71803-73341 98.8% 80.90 149.30 125.62 103.26 61.17 16.44 115.10 114.44 38.81 0.42 0.46 0.16 -1.56 -1.16 Matched[577]
YCL026C-B HBN1 Putative protein of unknown function; similar to bacterial nitroreductases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus Uncharacterized chr3:73405-73986 73405-73986 98.4% 38.42 34.93 54.14 43.66 167.66 117.01 36.68 48.90 142.34 0.14 0.20 0.59 1.54 NaN Matched[578]
YCL026C-A FRM2 "Protein of unknown function, involved in the integration of lipid signaling pathways with cellular homeostasis; similar to bacterial nitroreductases" Verified chr3:74704-75285 74704-75285 98.6% 12.20 5.23 12.20 8.71 10.45 1.74 8.71 10.45 6.10 0.03 0.04 0.03 -0.78 -1.26
YCL025C AGP1 "Low-affinity amino acid permease with broad substrate range, involved in uptake of asparagine, glutamine, and other amino acids; expression is regulated by the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p)" Verified chr3:76018-77919 76018-77919 97.4% 599.88 876.33 512.95 443.29 176.56 184.66 738.10 478.12 180.61 2.72 1.94 0.75 -1.40 -0.83 Frag>80[579,580]
YCL024W KCC4 "Protein kinase of the bud neck involved in the septin checkpoint, associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p" Verified chr3:79162-82275 79162-82275 98.6% 130.32 111.75 99.37 76.89 30.95 33.56 121.03 88.13 32.25 0.45 0.36 0.13 -1.45 -1.04 Matched[581]
YCL023C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF KCC4" Dubious chr3:78949-79296 78949-79296 98.4% 35.05 20.44 43.81 17.52 2.92 8.76 27.74 30.66 5.84 0.10 0.12 0.02 -2.39 -0.25 Overlap[581]
YCL022C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps verified gene KCC4/YCL024W" Dubious chr3:81570-82085 81570-82085 98.2% 175.60 155.87 146.00 92.73 69.06 39.46 165.73 119.37 54.26 0.61 0.48 0.22 -1.14 -0.37 Covered/w/another[581]
YCL021W-A Putative protein of unknown function Uncharacterized chr3:83620-83997 83620-83997 99.1% 261.62 285.65 216.24 152.17 152.17 120.13 273.64 184.20 136.15 1.01 0.75 0.56 -0.44 0.24 Matched[582]
YCL018W LEU2 "Beta-isopropylmalate dehydrogenase (IMDH), catalyzes the third step in the leucine biosynthesis pathway" Verified chr3:91324-92418 91324-92418 98.8% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.17
YCL017C NFS1 Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis; required for the post-transcriptional thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria Verified chr3:92777-94270 92777-94270 98.9% 295.85 234.92 293.15 306.69 241.02 264.71 265.39 299.92 252.86 0.98 1.22 1.05 -0.25 0.38 Frag>80[584,585]
YCL016C DCC1 "Subunit of a complex with Ctf8p and Ctf18p that shares some components with Replication Factor C, required for sister chromatid cohesion and telomere length maintenance" Verified chr3:94621-95763 94621-95763 99.1% 63.59 54.76 51.23 46.81 49.46 28.26 59.18 49.02 38.86 0.22 0.20 0.16 -0.33 0.27 Matched[586]
YCL014W BUD3 Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding Verified chr3:96281-101191 96281-101191 98.7% 84.15 61.46 61.46 62.08 41.46 56.31 72.81 61.77 48.88 0.27 0.25 0.20 -0.34 0.12 Matched[587]
YCL012C "Putative protein of unknown function; orthologs are present in S. bayanus, S. paradoxus and Ashbya gossypii; YCL012C is not an essential gene" Verified chr3:101317-101788 101317-101633,101701-101788 99.2% 144.38 149.36 144.38 126.96 214.09 166.79 146.87 135.67 190.44 0.54 0.55 0.79 0.49 NaN Covered/w/another[587]
YCL011C GBP2 "Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Hrb1p and Npl3p; also binds single-stranded telomeric repeat sequence in vitro" Verified chr3:102075-103358 102075-103358 99.2% 675.85 636.60 587.93 536.91 531.41 371.28 656.22 562.42 451.35 2.42 2.28 1.87 -0.32 -0.08 Frag<80[588]
YCL010C SGF29 SaGa associated Factor 29kDa; Probable 29kKDa Subunit of SAGA histone acetyltransferase complex Verified chr3:103571-104350 103571-104350 98.8% 149.25 181.69 146.65 103.82 232.30 166.12 165.47 125.24 199.21 0.61 0.51 0.83 0.67 0.88 Covered[589]
YCL009C ILV6 "Regulatory subunit of acetolactate synthase, which catalyzes the first step of branched-chain amino acid biosynthesis; enhances activity of the Ilv2p catalytic subunit, localizes to mitochondria" Verified chr3:104619-105548 104619-105548 98.4% 1002.14 1572.61 1030.55 1016.35 707.07 825.10 1287.37 1023.45 766.09 4.75 4.15 3.17 -0.42 0.09 Matched[590]
YCL008C STP22 "Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; homologous to the mouse and human Tsg101 tumor susceptibility gene; mutants exhibit a Class E Vps phenotype" Verified chr3:105696-106853 105696-106853 98.4% 144.74 175.44 134.22 95.62 193.87 191.24 160.09 114.92 192.55 0.59 0.47 0.80 0.74 1.19 Matched[591]
YCL005W-A VMA9 Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex; essential for vacuolar acidification; interacts with the V-ATPase assembly factor Vma21p in the ER; involved in V0 biogenesis Verified chr3:107023-107417 107023-107033,107111-107191,107288-107417 98.9% 1265.55 1547.80 983.31 974.20 1065.25 646.43 1406.68 978.76 855.84 5.19 3.97 3.55 -0.19 NaN Matched[592]
YCL007C "Dubious ORF unlikely to encode a protein; overlaps verified ORF YCL005W-A; mutations in YCL007C were thought to confer sensitivity to calcofluor white, but this phenotype was later shown to be due to the defect in YCL005W-A" Dubious chr3:106974-107366 106974-107366 99.1% 472.35 587.87 387.64 379.93 446.68 269.55 530.11 383.78 358.11 1.96 1.56 1.48 -0.10 -0.10 Frag<80[592]
YCL005W LDB16 Protein of unknown function; null mutants have decreased net negative cell surface charge; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS; native protein is detected in purified mitochondria Verified chr3:108021-108791 108021-108791 99.0% 168.94 213.47 172.87 136.20 137.51 127.03 191.20 154.53 132.27 0.71 0.63 0.55 -0.22 -0.20 Covered/w/another[593]
YCL004W PGS1 "Phosphatidylglycerolphosphate synthase, catalyzes the synthesis of phosphatidylglycerolphosphate from CDP-diacylglycerol and sn-glycerol 3-phosphate in the first committed and rate-limiting step of cardiolipin biosynthesis" Verified chr3:109105-110670 109105-110670 99.0% 94.22 113.58 78.73 89.70 105.19 87.12 103.90 84.21 96.15 0.38 0.34 0.40 0.19 0.18 Covered/w/another[593]
YCL002C Putative protein of unknown function; YCL002C is not an essential gene Uncharacterized chr3:110843-111674 110843-111556,111633-111674 99.0% 183.07 145.66 152.34 163.03 130.96 70.82 164.37 157.68 100.89 0.61 0.64 0.42 -0.64 -1.11 Covered/w/another[593]
YCL001W RER1 "Protein involved in retention of membrane proteins, including Sec12p, in the ER; localized to Golgi; functions as a retrieval receptor in returning membrane proteins to the ER" Verified chr3:111914-112480 111914-112480 99.1% 582.15 532.30 612.42 505.60 639.12 284.85 557.23 559.01 461.98 2.06 2.27 1.91 -0.28 -0.67 Matched[594]
YCL001W-A Putative protein of unknown function; YCL001W-A is not an essential gene Uncharacterized chr3:113078-113539 113078-113539 98.9% 17.51 26.27 13.14 8.76 24.08 17.51 21.89 10.95 20.80 0.08 0.04 0.09 0.93 0.41 Matched[595]
YCL001W-B Putative protein of unknown function; identified by homology Uncharacterized chr3:113768-114022 113768-114022 98.2% 35.93 51.90 55.89 35.93 75.85 87.82 43.91 45.91 81.84 0.16 0.19 0.34 0.83 0.83 Covered/w/another[595]
YCR001W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YCR001W is not an essential gene" Dubious chr3:115683-115997 115683-115997 99.5% 28.71 22.33 28.71 22.33 28.71 15.95 25.52 25.52 22.33 0.09 0.10 0.09 -0.19 0.07 Covered[596]
YCR002C CDC10 "Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM" Verified chr3:117378-118346 117378-118346 99.2% 430.86 365.29 351.76 395.47 345.52 276.83 398.07 373.62 311.17 1.47 1.52 1.29 -0.26 -0.06 Matched[597]
YCR003W MRPL32 Mitochondrial ribosomal protein of the large subunit Verified chr3:118618-119169 118618-119169 98.7% 286.33 278.98 273.48 266.14 352.40 189.05 282.66 269.81 270.72 1.04 1.10 1.12 0.00 -0.80 Frag>80[598,599]
YCR004C YCP4 "Protein of unknown function, has sequence and structural similarity to flavodoxins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr3:119573-120316 119573-120316 98.8% 1200.48 1508.08 1510.80 1433.22 3284.30 2414.56 1354.28 1472.01 2849.43 5.00 5.98 11.81 0.95 0.64 Matched[600]
YCR005C CIT2 "Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate, peroxisomal isozyme involved in glyoxylate cycle; expression is controlled by Rtg1p and Rtg2p transcription factors" Verified chr3:120944-122326 120944-122326 99.1% 408.57 774.83 436.30 271.41 723.03 390.33 591.70 353.85 556.68 2.18 1.44 2.31 0.65 0.86 Matched[602]
YCR006C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr3:122528-123001 122528-123001 98.6% 14.98 27.82 36.38 21.40 32.10 23.54 21.40 28.89 27.82 0.08 0.12 0.12 -0.05 0.71 Matched[603]
YCR007C "Putative integral membrane protein, member of DUP240 gene family; YCR007C is not an essential gene" Uncharacterized chr3:126009-126728 126009-126728 99.1% 46.23 51.84 50.43 23.82 91.06 100.87 49.03 37.13 95.97 0.18 0.15 0.40 1.37 1.27 Covered[605]
YCR008W SAT4 Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; partially redundant with Hal5p; has similarity to Npr1p Verified chr3:128468-130279 128468-130279 98.8% 315.72 282.20 307.90 268.78 455.98 405.69 298.96 288.34 430.84 1.10 1.17 1.79 0.58 0.60 Matched[606]
YCR009C RVS161 "Amphiphysin-like lipid raft protein; subunit of a complex (Rvs161p-Rvs167p) that regulates polarization of the actin cytoskeleton, endocytosis, cell polarity, cell fusion and viability following starvation or osmotic stress" Verified chr3:130743-131540 130743-131540 99.5% 656.24 823.76 701.58 791.01 1250.76 904.38 740.00 746.30 1077.57 2.73 3.03 4.46 0.53 0.26 Matched[607]
YCR010C ADY2 Acetate transporter required for normal sporulation; phosphorylated in mitochondria Verified chr3:132271-133122 132271-133122 99.0% 2.37 17.79 8.30 3.56 40.33 17.79 10.08 5.93 29.06 0.04 0.02 0.12 2.29 1.31 Frag<80[608,609]
YCR011C ADP1 Putative ATP-dependent permease of the ABC transporter family of proteins Verified chr3:133722-136871 133722-136871 99.2% 287.83 338.42 329.14 307.36 516.76 477.05 313.13 318.25 496.90 1.16 1.29 2.06 0.64 1.23 Matched[610]
YCR012W PGK1 "3-phosphoglycerate kinase, catalyzes transfer of high-energy phosphoryl groups from the acyl phosphate of 1,3-bisphosphoglycerate to ADP to produce ATP; key enzyme in glycolysis and gluconeogenesis" Verified chr3:137744-138994 137744-138994 98.5% 26237.50 28129.40 25080.62 23338.81 39325.83 26912.48 27183.45 24209.71 33119.16 100.35 98.27 137.22 0.45 -0.74 Frag>80[611,612]
YCR013C "ubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; transcription of both YCR013C and the overlapping essential gene PGK1 is reduced in the gcr1 null mutant" Dubious chr3:138400-139047 138400-139047 98.6% 31481.31 33417.78 29745.22 26988.46 49781.49 30664.14 32449.55 28366.84 40222.82 119.79 115.15 166.66 0.50 -0.08 Matched[612]
YCR014C POL4 "DNA polymerase IV, undergoes pair-wise interactions with Dnl4p-Lif1p and Rad27p to mediate repair of DNA double-strand breaks by non-homologous end joining (NHEJ); homologous to mammalian DNA polymerase beta" Verified chr3:139183-140931 139183-140931 99.5% 103.48 117.28 70.71 59.79 33.34 29.90 110.38 65.25 31.62 0.41 0.26 0.13 -1.05 -0.91 Covered/w/another[613]
YCR015C Putative protein of unknown function; YCR015C is not an essential gene Uncharacterized chr3:141215-142168 141215-142168 99.3% 79.13 82.30 85.46 88.63 54.86 53.81 80.71 87.04 54.34 0.30 0.35 0.23 -0.68 -0.01 Covered/w/another[613]
YCR016W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus and nucleus; YCR016W is not an essential gene Uncharacterized chr3:143632-144504 143632-144504 98.2% 314.99 168.00 169.16 163.33 31.50 18.67 241.49 166.25 25.08 0.89 0.67 0.10 -2.73 -2.64 Matched[615]
YCR017C CWH43 Putative sensor/transporter protein involved in cell wall biogenesis; contains 14-16 transmembrane segments and several putative glycosylation and phosphorylation sites; null mutation is synthetically lethal with pkc1 deletion Verified chr3:144771-147632 144771-147632 98.8% 371.56 420.71 360.96 359.19 155.55 153.79 396.13 360.07 154.67 1.46 1.46 0.64 -1.22 -0.52 Matched[616]
YCR018C SRD1 Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation Verified chr3:148236-148901 148236-148901 99.3% 185.96 312.96 172.36 158.75 359.83 173.87 249.46 165.55 266.85 0.92 0.67 1.11 0.69 0.44 Frag<80[617,618]
YCR018C-A Putative protein of unknown function; encoded opposite a Ty1 LTR Dubious chr3:151606-151860 151606-151860 26.9% 43.69 14.56 14.56 43.69 87.38 87.38 29.13 29.13 87.38 0.11 0.12 0.36 1.58 0.87 Frag<80[619]
YCR019W MAK32 Protein necessary for structural stability of L-A double-stranded RNA-containing particles Verified chr3:152835-153926 152835-153926 98.7% 65.90 71.47 70.54 56.62 82.61 77.97 68.69 63.58 80.29 0.25 0.26 0.33 0.34 0.60 Matched[620]
YCR020C PET18 Protein required for respiratory growth and stability of the mitochondrial genome Verified chr3:154010-154657 154010-154657 99.2% 40.46 45.13 28.01 21.79 24.90 18.67 42.79 24.90 21.79 0.16 0.10 0.09 -0.19 0.19 Matched[621]
YCR020C-A MAK31 Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; required for replication of dsRNA virus; member of the Sm protein family Verified chr3:154828-155094 154828-155094 99.1% 287.29 257.05 215.47 253.27 154.99 117.18 272.17 234.37 136.08 1.00 0.95 0.56 -0.78 -0.97 Matched[622]
YCR020W-B HTL1 "Component of the RSC chromatin remodeling complex; RSC functions in transcriptional regulation and elongation, chromosome stability, and establishing sister chromatid cohesion; involved in telomere maintenance" Verified chr3:155318-155554 155318-155554 98.5% 180.00 137.14 192.86 68.57 111.43 34.29 158.57 130.71 72.86 0.59 0.53 0.30 -0.84 -0.61 Matched[623]
YCR021C HSP30 "Hydrophobic plasma membrane localized, stress-responsive protein that negatively regulates the H(+)-ATPase Pma1p; induced by heat shock, ethanol treatment, weak organic acid, glucose limitation, and entry into stationary phase" Verified chr3:156105-157103 156105-157103 98.9% 56.71 82.02 47.59 43.54 7786.00 5730.39 69.36 45.57 6758.20 0.26 0.18 28.00 7.21 4.68 Frag>80[624,625]
YCR022C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YCR022C is not an essential gene" Dubious chr3:157417-157761 157417-157761 98.2% 5.90 11.80 14.75 5.90 2.95 2.95 8.85 10.33 2.95 0.03 0.04 0.01 -1.81 -1.17 Frag<80[626]
YCR023C Putative protein of unknown function; YCR023C is not an essential gene Uncharacterized chr3:158534-160369 158534-160369 99.0% 184.23 257.93 145.19 154.54 171.59 142.99 221.08 149.86 157.29 0.82 0.61 0.65 0.07 -0.12 Matched[627]
YCR024C SLM5 Mitochondrial asparaginyl-tRNA synthetase Verified chr3:160740-162218 160740-162218 99.1% 58.01 70.98 70.98 80.54 81.22 73.71 64.50 75.76 77.47 0.24 0.31 0.32 0.03 0.14 Matched[628]
YCR024C-B Putative protein of unknown function; identified by expression profiling and mass spectrometry Uncharacterized chr3:162595-162861 162595-162861 98.8% 8441.14 7167.01 6465.48 5525.04 3382.52 2093.22 7804.08 5995.26 2737.87 28.81 24.34 11.34 -1.13 NaN Matched[629]
YCR024C-A PMP1 "Small single-membrane span proteolipid that functions as a regulatory subunit of the plasma membrane H(+)-ATPase Pma1p, forms unique helix and positively charged cytoplasmic domain that is able to specifically segregate phosphatidylserines" Verified chr3:162941-163063 162941-163063 83.3% 7059.40 6366.15 5819.37 4979.66 3290.48 2060.21 6712.77 5399.51 2675.35 24.78 21.92 11.08 -1.01 -0.73 Matched[629]
YCR025C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YCR025C is not an essential gene" Dubious chr3:163442-163852 163442-163852 98.7% 12.33 19.73 22.20 12.33 41.93 39.46 16.03 17.26 40.69 0.06 0.07 0.17 1.24 0.87 Matched[630]
YCR026C NPP1 Nucleotide pyrophosphatase/phosphodiesterase family member; mediates extracellular nucleotide phosphate hydrolysis along with Npp2p and Pho5p; activity and expression enhanced during conditions of phosphate starvation Verified chr3:164107-166335 164107-166335 99.2% 128.46 137.51 105.39 108.11 89.11 108.56 132.98 106.75 98.83 0.49 0.43 0.41 -0.11 0.56 Matched[631]
YCR027C RHB1 Putative Rheb-related GTPase involved in regulating canavanine resistance and arginine uptake; member of the Ras superfamily of G-proteins Verified chr3:167366-167995 167366-167995 99.1% 124.89 86.46 120.09 121.69 96.07 91.27 105.68 120.89 93.67 0.39 0.49 0.39 -0.37 -0.08 Matched[633]
YCR028C FEN2 Plasma membrane H+-pantothenate symporter; confers sensitivity to the antifungal agent fenpropimorph Verified chr3:170882-172420 170882-172420 99.1% 111.46 106.22 100.32 84.58 32.78 34.09 108.84 92.45 33.44 0.40 0.38 0.14 -1.47 -0.83 Covered[636]
YCR028C-A RIM1 Single-stranded DNA-binding protein essential for mitochondrial genome maintenance; involved in mitochondrial DNA replication Verified chr3:172946-173436 172946-173111,173195-173436 98.9% 1238.90 971.30 1105.10 1062.98 971.30 552.55 1105.10 1084.04 761.92 4.08 4.40 3.16 -0.51 -0.74 Matched[637]
YCR030C SYP1 Protein with a potential role in actin cytoskeletal organization; overexpression suppresses a pfy1 (profilin) null mutation Verified chr3:173822-176434 173822-176434 98.7% 157.73 190.67 207.34 196.10 244.93 308.10 174.20 201.72 276.51 0.64 0.82 1.15 0.46 1.19 Matched[638]
YCR031C RPS14A "Ribosomal protein 59 of the small subunit, required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; nearly identical to Rps14Bp and similar to E. coli S11 and rat S14 ribosomal proteins" Verified chr3:177496-178216 177496-177902,178210-178216 64.7% 10486.71 9180.53 9535.07 8019.90 3713.26 2791.48 9833.62 8777.48 3252.37 36.30 35.63 13.48 -1.43 -1.63 Frag>80[639,640,641]
YCR032W BPH1 "PProtein homologous to human Chediak-Higashi syndrome and murine Beige proteins, which are implicated in disease syndromes due to defective lysosomal trafficking; mutant phenotype and genetic interactions suggest a role in protein sorting" Verified chr3:179516-186019 179516-186019 99.0% 36.67 45.84 34.50 32.63 31.08 36.98 41.25 33.56 34.03 0.15 0.14 0.14 0.02 0.10 Frag>80[642,643]
YCR033W SNT1 "Subunit of the Set3C deacetylase complex that interacts directly with the Set3C subunit, Sif2p; putative DNA-binding protein" Verified chr3:186485-190165 186485-190165 98.6% 203.91 184.62 167.26 158.99 114.91 164.50 194.26 163.13 139.70 0.72 0.66 0.58 -0.22 0.64 Matched[644]
YCR034W FEN1 "Fatty acid elongase, involved in sphingolipid biosynthesis; acts on fatty acids of up to 24 carbons in length; mutations have regulatory effects on 1,3-beta-glucan synthase, vacuolar ATPase, and the secretory pathway" Verified chr3:190588-191631 190588-191631 99.2% 842.04 739.68 781.20 722.30 174.78 132.29 790.86 751.75 153.54 2.92 3.05 0.64 -2.29 -1.86 Matched[645]
YCR035C RRP43 "Protein involved in rRNA processing; component of the exosome 3->5 exonuclease complex with Rrp41p, Rrp42p, Rrp4p and Dis3p; required for efficient maturation of 5.8S, 18S and 25S rRNA" Verified chr3:191830-193014 191830-193014 99.2% 223.69 188.82 215.18 179.46 155.65 103.76 206.25 197.32 129.70 0.76 0.80 0.54 -0.61 -0.71 Matched[646]
YCR036W RBK1 Putative ribokinase Verified chr3:193293-194294 193293-194294 98.6% 228.71 223.65 242.87 240.85 498.90 376.45 226.18 241.86 437.68 0.83 0.98 1.81 0.86 0.74 Matched[647]
YCR037C PHO87 "Low-affinity inorganic phosphate (Pi) transporter, involved in activation of PHO pathway; expression is independent of Pi concentration and Pho4p activity; contains 12 membrane-spanning segments" Verified chr3:194410-197181 194410-197181 98.8% 109.91 101.51 79.24 64.63 96.03 69.01 105.71 71.93 82.52 0.39 0.29 0.34 0.20 0.66 Matched[648]
YCR038W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene BUD5/YCR038C; identified by homology with hemiascomycetous yeast species" Dubious chr3:199289-199414 199289-199414 4.4% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN -0.25
YCR038C BUD5 GTP/GDP exchange factor for Rsr1p (Bud1p) required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types Verified chr3:197617-199545 197617-199545 54.8% 53.02 55.86 49.23 37.87 72.90 51.12 54.44 43.55 62.01 0.20 0.18 0.26 0.51 1.10 Frag<80[649]
YCR039C MATALPHA2 "Homeobox-domain protein that, with Mcm1p, represses a-specific genes in haploids; acts with A1p to repress transcription of haploid-specific genes in diploids; one of two genes encoded by the MATalpha mating type cassette" Verified chr3:199542-200174 199542-200174 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.19
YCR040W MATALPHA1 Transcriptional co-activator involved in regulation of mating-type-specific gene expression; targets the transcription factor Mcm1p to the promoters of alpha-specific genes; one of two genes encoded by the MATalpha mating type cassette Verified chr3:200438-200965 200438-200965 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.47
YCR041W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr3:200907-201239 200907-201239 28.0% 289.54 246.65 203.75 171.58 214.48 117.96 268.10 187.67 166.22 0.99 0.76 0.69 -0.18 0.52 Overlap[650]
YCR042C TAF2 "TFIID subunit (150 kDa), involved in RNA polymerase II transcription initiation" Verified chr3:201170-205393 201170-205393 99.3% 114.92 113.72 93.70 87.50 92.74 90.12 114.32 90.60 91.43 0.42 0.37 0.38 0.01 0.37 Matched[650]
YCR043C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the Golgi apparatus; YCR043C is not an essential gene Uncharacterized chr3:206257-206640 206257-206640 99.4% 316.89 316.89 316.89 261.89 191.18 170.23 316.89 289.39 180.71 1.17 1.17 0.75 -0.68 -0.47 Matched[652]
YCR044C PER1 "Protein of the endoplasmic reticulum, required for GPI-phospholipase A2 activity that remodels the GPI anchor as a prerequisite for association of GPI-anchored proteins with lipid rafts; functionally complemented by human ortholog PERLD1" Verified chr3:206873-207946 206873-207946 98.9% 317.43 328.73 290.11 281.63 254.32 184.62 323.08 285.87 219.47 1.19 1.16 0.91 -0.38 -0.47 Matched[653]
YCR045W-A "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps with YCR045C; identified by gene-trapping, microarray expression analysis, and genome-wide homology searching" Dubious chr3:208747-209097 208747-209097 99.0% 77.72 100.74 51.81 40.30 86.35 63.32 89.23 46.05 74.84 0.33 0.19 0.31 0.70 NaN Covered/w/another[654]
YCR045C Putative protein of unknown function Uncharacterized chr3:208131-209606 208131-209606 98.7% 87.86 110.51 69.33 54.23 64.52 67.27 99.19 61.78 65.90 0.37 0.25 0.27 0.09 1.68 Matched[654]
YCR046C IMG1 "Mitochondrial ribosomal protein of the large subunit, required for respiration and for maintenance of the mitochondrial genome" Verified chr3:209910-210419 209910-210419 98.5% 394.23 440.02 495.77 358.39 515.68 310.60 417.12 427.08 413.14 1.54 1.73 1.71 -0.05 0.07 Matched[655]
YCR047W-A "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps with YCR047C; identified by gene-trapping, microarray expression analysis, and genome-wide homology searching" Dubious chr3:211297-211503 211297-211503 99.0% 151.28 112.24 126.88 63.44 14.64 9.76 131.76 95.16 12.20 0.49 0.39 0.05 -2.96 NaN Covered/w/another[656]
YCR047C BUD23 Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern Verified chr3:210714-211541 210714-211541 98.9% 163.56 147.70 108.64 96.43 19.53 20.75 155.63 102.53 20.14 0.57 0.42 0.08 -2.35 -2.24 Matched[656]
YCR048W ARE1 "Acyl-CoA:sterol acyltransferase, isozyme of Are2p; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the absence of oxygen" Verified chr3:211925-213757 211925-213757 98.4% 135.34 229.64 123.14 97.62 145.88 166.40 182.49 110.38 156.14 0.67 0.45 0.65 0.50 0.77 Matched[657]
YCR049C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr3:211867-212313 211867-212313 97.9% 66.29 157.73 70.86 48.00 73.15 114.30 112.01 59.43 93.72 0.41 0.24 0.39 0.66 0.04 Covered/w/another[657]
YCR050C Non-essential protein of unknown function; deletion mutant is synthetically sick or lethal with alpha-synuclein Uncharacterized chr3:213460-213768 213460-213768 98.9% 193.15 360.11 193.15 157.14 304.46 235.71 276.63 175.15 270.09 1.02 0.71 1.12 0.62 0.13 Covered/w/another[657]
YCR051W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; contains ankyrin (Ank) repeats; YCR051W is not an essential gene Uncharacterized chr3:214067-214735 214067-214735 97.6% 330.84 197.59 283.36 240.47 111.81 85.77 264.22 261.92 98.79 0.98 1.06 0.41 -1.41 -1.20 Matched[658]
YCR052W RSC6 Component of the RSC chromatin remodeling complex; essential for mitotic growth; homolog of SWI/SNF subunit Swp73p Verified chr3:214990-216441 214990-216441 98.4% 224.57 270.74 220.37 196.58 139.92 121.73 247.65 208.48 130.82 0.91 0.85 0.54 -0.67 -0.00 Matched[659]
YCR053W THR4 "Threonine synthase, conserved protein that catalyzes formation of threonine from 0-phosphohomoserine; expression is regulated by the GCN4-mediated general amino acid control pathway" Verified chr3:216693-218237 216693-218237 98.9% 1060.46 1058.50 1042.14 997.66 436.35 417.38 1059.48 1019.90 426.87 3.91 4.14 1.77 -1.26 -0.51 Matched[660]
YCR054C CTR86 Essential protein of unknown function; upstream region contains a Gcn4p responsive site suggesting a possible role in amino acid biosynthesis Verified chr3:218372-220063 218372-220063 99.1% 54.26 50.09 39.35 28.62 28.62 22.66 52.17 33.99 25.64 0.19 0.14 0.11 -0.41 -0.08 Matched[661]
YCR057C PWP2 "Conserved 90S pre-ribosomal component essential for proper endonucleolytic cleavage of the 35 S rRNA precursor at A0, A1, and A2 sites; contains eight WD-repeats; PWP2 deletion leads to defects in cell cycle and bud morphogenesis" Verified chr3:220453-223224 220453-223224 99.1% 176.59 117.97 107.78 75.37 8.37 5.46 147.28 91.57 6.92 0.54 0.37 0.03 -3.73 -4.23 Matched[662]
YCR059C YIH1 "Protein that inhibits activation of Gcn2p, an eIF2 alpha subunit protein kinase, by competing for Gcn1p binding, thus impacting gene expression in response to starvation; has sequence and functional similarity to the mouse IMPACT gene" Verified chr3:223450-224226 223450-224226 98.3% 346.99 335.21 306.40 260.57 69.40 73.33 341.10 283.49 71.36 1.26 1.15 0.30 -1.99 -1.26 Matched[663]
YCR060W TAH1 "HSP90 cofactor; interacts with Hsp82p, Pih1p, Rvb1 and Rvb2, contains a single TPR domain with at least two TPR motifs" Verified chr3:224395-224730 224395-224730 98.0% 206.43 291.42 212.50 173.03 145.71 97.14 248.92 192.76 121.43 0.92 0.78 0.50 -0.67 -1.26 Covered/w/another[663]
YCR061W Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern Uncharacterized chr3:225559-227454 225559-227454 98.8% 141.99 256.23 165.48 166.55 369.40 409.43 199.11 166.01 389.41 0.74 0.67 1.61 1.23 1.68 Matched[664]
YCR063W BUD31 Protein involved in bud-site selection; analysis of integrated high-throughput datasets predicts an involvement in RNA splicing; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern Verified chr3:228314-228787 228314-228787 98.4% 79.36 49.33 68.64 42.90 17.16 60.06 64.35 55.77 38.61 0.24 0.23 0.16 -0.53 -0.36 Covered/w/another[666]
YCR064C "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the verified gene BUD31" Dubious chr3:228091-228501 228091-228501 98.6% 44.41 32.08 41.95 29.61 12.34 37.01 38.24 35.78 24.67 0.14 0.15 0.10 -0.54 0.17 Overlap[666]
YCR065W HCM1 "Forkhead transcription factor that drives S-phase specific expression of genes involved in chromosome segregation, spindle dynamics, and budding; suppressor of calmodulin mutants with specific SPB assembly defects; telomere maintenance role" Verified chr3:229306-231000 229306-231000 98.7% 208.06 199.09 166.81 162.62 95.66 88.49 203.58 164.72 92.07 0.75 0.67 0.38 -0.84 -0.21 Covered/w/another[666]
YCR066W RAD18 Protein involved in postreplication repair; binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; forms heterodimer with Rad6p; contains RING-finger motif Verified chr3:231496-232959 231496-232959 98.8% 49.08 43.55 38.02 44.93 49.08 60.14 46.31 41.47 54.61 0.17 0.17 0.23 0.40 0.80 Matched[667]
YCR067C SED4 "Integral endoplasmic reticulum membrane protein, functions as a positive regulator of Sar1p probably through inhibition of GTPase activation by Sec23p; binds Sec16p, participates in vesicle formation, similar to Sec12p" Verified chr3:233121-236318 233121-236318 97.1% 142.01 148.45 146.51 123.33 115.60 144.26 145.23 134.92 129.93 0.54 0.55 0.54 -0.05 0.62 Matched[668]
YCR068W ATG15 "Lipase, required for intravacuolar lysis of autophagic bodies; located in the endoplasmic reticulum membrane and targeted to intravacuolar vesicles during autophagy via the multivesicular body (MVB) pathway" Verified chr3:237210-238772 237210-238772 98.4% 53.34 78.71 59.85 50.09 62.45 93.67 66.03 54.97 78.06 0.24 0.22 0.32 0.51 1.32 Matched[669]
YCR069W CPR4 "Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; has a potential role in the secretory pathway" Verified chr3:239051-240007 239051-240007 98.9% 462.84 719.62 518.84 539.98 456.50 439.59 591.23 529.41 448.05 2.18 2.15 1.86 -0.24 0.32 Matched[670]
YCR071C IMG2 Mitochondrial ribosomal protein of the small subunit Verified chr3:240099-240539 240099-240539 99.2% 272.05 304.06 301.77 221.76 372.64 198.90 288.05 261.76 285.77 1.06 1.06 1.18 0.13 -0.16 Matched[671]
YCR072C RSA4 "WD-repeat protein involved in ribosome biogenesis; may interact with ribosomes; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits, localizes to the nucleolus" Verified chr3:240801-242348 240801-242348 98.9% 117.55 102.53 84.90 58.77 9.80 4.57 110.04 71.83 7.18 0.41 0.29 0.03 -3.32 -3.61 Covered/w/another[672]
YCR073C SSK22 "MAP kinase kinase kinase of the HOG1 mitogen-activated signaling pathway; functionally redundant with, and homologous to, Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p" Verified chr3:242585-246580 242585-246580 99.2% 49.45 60.55 35.83 32.80 11.35 14.63 55.00 34.31 12.99 0.20 0.14 0.05 -1.40 -0.86 Covered/w/another[672]
YCR073W-A SOL2 "Protein with a possible role in tRNA export; shows similarity to 6-phosphogluconolactonase non-catalytic domains but does not exhibit this enzymatic activity; homologous to Sol1p, Sol3p, and Sol4p" Verified chr3:246960-247907 246960-247907 98.3% 148.06 207.07 196.34 181.32 383.03 293.98 177.57 188.83 338.50 0.66 0.77 1.40 0.84 0.69 Matched[673]
YCR075C ERS1 "Protein with similarity to human cystinosin, which is a H(+)-driven transporter involved in L-cystine export from lysosomes and implicated in the disease cystinosis; contains seven transmembrane domains" Verified chr3:248030-248812 248030-248812 99.0% 116.12 163.86 143.22 136.77 174.18 118.70 139.99 139.99 146.44 0.52 0.57 0.61 0.06 0.19 Matched[674]
YCR075W-A Putative protein of unknown function; identified by homology to Ashbya gossypii Uncharacterized chr3:248972-249199 248972-249199 98.8% 235.21 248.52 248.52 204.14 319.53 306.21 241.86 226.33 312.87 0.89 0.92 1.30 0.47 NaN Covered/w/another[675]
YCR076C Putative protein of unknown function; YCR076C is not an essential gene Uncharacterized chr3:249290-250042 249290-250042 99.0% 144.89 187.82 160.99 119.40 347.48 224.05 166.36 140.20 285.76 0.61 0.57 1.18 1.03 0.78 Matched[675]
YCR077C PAT1 "Topoisomerase II-associated deadenylation-dependent mRNA-decapping factor; also required for faithful chromosome transmission, maintenance of rDNA locus stability, and protection of mRNA 3'-UTRs from trimming; functionally linked to Pab1p" Verified chr3:250235-252625 250235-252625 98.8% 334.03 289.58 326.41 275.61 219.73 236.66 311.81 301.01 228.19 1.15 1.22 0.95 -0.40 0.12 Matched[676]
YCR079W PTC6 Phosphoprotein phosphatase type 2C similar to mammalian PP1Ks; involved in mitophagy; localized to mitochondrial inner membrane space; null mutant is sensitive to rapamycin Verified chr3:252842-254170 252842-254170 98.4% 87.16 100.15 116.97 115.44 196.48 181.19 93.65 116.21 188.84 0.35 0.47 0.78 0.70 1.04 Matched[677]
YCR081W SRB8 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in glucose repression Verified chr3:254368-258651 254368-258651 99.1% 33.22 32.28 27.33 32.75 22.62 27.33 32.75 30.04 24.98 0.12 0.12 0.10 -0.27 0.42 Matched[678]
YCR081C-A "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps with SRB8/YCR081W; identified by gene-trapping, microarray expression analysis, and genome-wide homology searching" Dubious chr3:258412-258648 258412-258648 98.9% 93.88 46.94 76.81 93.88 42.67 51.21 70.41 85.35 46.94 0.26 0.35 0.19 -0.86 NaN Covered/w/another[678]
YCR082W AHC2 "Protein of unknown function, putative transcriptional regulator; proposed to be a Ada Histone acetyltransferase complex component; GFP tagged protein is localized to the cytoplasm and nucleus" Verified chr3:258880-259266 258880-259266 98.7% 429.18 361.14 491.99 476.28 1350.34 803.40 395.16 484.13 1076.87 1.46 1.97 4.46 1.15 0.55 Matched[679]
YCR083W TRX3 "Mitochondrial thioredoxin, highly conserved oxidoreductase required to maintain the redox homeostasis of the cell, forms the mitochondrial thioredoxin system with Trr2p, redox state is maintained by both Trr2p and Glr1p" Verified chr3:259575-259958 259575-259958 98.7% 190.06 240.21 248.13 245.49 834.14 432.91 215.13 246.81 633.52 0.79 1.00 2.62 1.36 0.72 Covered/w/another[680]
YCR084C TUP1 "General repressor of transcription, forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes" Verified chr3:260308-262449 260308-262449 98.6% 558.40 527.62 538.04 519.09 356.64 404.48 543.01 528.57 380.56 2.00 2.15 1.58 -0.47 0.10 Matched[680]
YCR085W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr3:262913-263266 262913-263266 99.2% 14.23 8.54 14.23 2.85 14.23 5.69 11.39 8.54 9.96 0.04 0.03 0.04 0.22 -0.43 Overlap[681]
YCR086W CSM1 "Nucleolar protein that forms a complex with Lrs4p which binds Mam1p at kinetochores during meiosis I to mediate accurate chromosome segregation, may be involved in premeiotic DNA replication; possible role in telomere maintenance" Verified chr3:263389-263961 263389-263961 98.5% 102.75 88.58 118.70 108.07 86.81 65.55 95.67 113.38 76.18 0.35 0.46 0.32 -0.57 -0.56 Matched[681]
YCR087W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps uncharacterized gene YCR087C-A; YCR087W is not an essential gene" Dubious chr3:263973-264488 263973-264488 97.4% 328.30 189.02 240.76 206.93 53.72 9.95 258.66 223.84 31.84 0.95 0.91 0.13 -2.81 -0.31 Matched[681]
YCR087C-A Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; YCR087C-A is not an essential gene Uncharacterized chr3:264003-264464 264003-264464 97.1% 336.52 193.89 236.23 222.86 51.26 11.14 265.21 229.55 31.20 0.98 0.93 0.13 -2.88 -1.84 Matched[681]
YCR088W ABP1 "Actin-binding protein of the cortical actin cytoskeleton, important for activation of the Arp2/3 complex that plays a key role actin in cytoskeleton organization" Verified chr3:265065-266843 265065-266843 98.3% 567.05 703.66 661.93 652.79 585.34 748.82 635.35 657.36 667.08 2.35 2.67 2.76 0.02 0.76 Matched[683]
YCR089W FIG2 "Cell wall adhesin, expressed specifically during mating; may be involved in maintenance of cell wall integrity during mating" Verified chr3:267431-272260 267431-272260 90.8% 59.48 64.27 57.66 52.19 20.28 26.66 61.87 54.92 23.47 0.23 0.22 0.10 -1.23 -0.37 Frag>80[684,685,686,687]
YCR090C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YCR090C is not an essential gene Uncharacterized chr3:272312-272860 272312-272860 99.4% 339.09 276.77 337.25 274.94 359.25 205.28 307.93 306.09 282.27 1.14 1.24 1.17 -0.12 -0.58 Matched[687]
YCR091W KIN82 "Putative serine/threonine protein kinase, most similar to cyclic nucleotide-dependent protein kinase subfamily and the protein kinase C subfamily" Verified chr3:274401-276563 274401-276563 98.3% 43.26 72.88 60.65 88.39 214.87 227.56 58.07 74.52 221.22 0.21 0.30 0.92 1.57 1.45 Matched[688]
YCR092C MSH3 "Mismatch repair protein, forms dimers with Msh2p that mediate repair of insertion or deletion mutations and removal of nonhomologous DNA ends, contains a PCNA (Pol30p) binding motif required for genome stability" Verified chr3:276761-279817 276761-279817 99.3% 50.09 57.67 45.48 43.83 47.45 33.94 53.88 44.65 40.70 0.20 0.18 0.17 -0.13 0.28 Frag>80[689]
YCR093W CDC39 "Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation; basal transcription factor" Verified chr3:280114-286440 280114-286440 99.0% 158.96 129.91 126.24 115.71 97.20 143.48 144.44 120.98 120.34 0.53 0.49 0.50 -0.01 0.52 Frag>80[690,691,692]
YCR094W CDC50 "Endosomal protein that regulates cell polarity, controls polarized growth; similar to Ynr048wp and Lem3p" Verified chr3:286759-287934 286759-287934 98.9% 168.59 146.23 133.32 125.58 123.00 87.74 157.41 129.45 105.37 0.58 0.53 0.44 -0.30 -0.05 Covered/w/another[693]
YCR095C "Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts" Uncharacterized chr3:288167-289255 288167-289255 99.4% 126.61 111.82 108.12 119.21 132.15 63.77 119.21 113.67 97.96 0.44 0.46 0.41 -0.21 -0.36 Covered/w/another[693]
YCR095W-A Putative protein of unknown function Uncharacterized chr3:289636-289794 289636-289794 98.7% 12.74 19.11 19.11 0.00 25.48 38.23 15.93 9.56 31.86 0.06 0.04 0.13 1.74 NaN Covered[694]
YCR096C HMRA2 Silenced copy of a2 at HMR; similarity to Alpha2p; required along with a1p for inhibiting expression of the HO endonuclease in a/alpha HO/HO diploid cells with an active mating-type interconversion system Verified|silenced_gene chr3:293176-293535 293176-293535 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.20
YCR097W HMRA1 Silenced copy of a1 at HMR; homeobox corepressor that interacts with Alpha2p to repress haploid-specific gene transcription in diploid cells Verified|silenced_gene chr3:293832-294318 293832-293936,293991-294236,294289-294318 98.9% 557.58 610.69 533.69 520.41 1160.31 581.48 584.14 527.05 870.89 2.16 2.14 3.61 0.72 -0.09 Matched[695]
YCR097W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; identified by homology to a hemiascomycetous yeast protein" Dubious chr3:294436-294702 294436-294702 47.2% 0.00 7.94 0.00 0.00 0.00 0.00 3.97 0.00 0.00 0.01 0.00 0.00 NaN 0.55
YCR098C GIT1 "Plasma membrane permease, mediates uptake of glycerophosphoinositol and glycerophosphocholine as sources of the nutrients inositol and phosphate; expression and transport rate are regulated by phosphate and inositol availability" Verified chr3:297046-298602 297046-298602 99.1% 18.79 25.91 15.55 13.60 27.86 20.73 22.35 14.58 24.29 0.08 0.06 0.10 0.74 0.50
YCR099C Putative protein of unknown function Uncharacterized chr3:300829-301296 300829-301296 96.3% 46.59 55.46 42.15 39.93 124.24 39.93 51.03 41.04 82.09 0.19 0.17 0.34 1.00 1.15 Covered/w/another[696]
YCR100C Putative protein of unknown function Uncharacterized chr3:301268-302218 301268-302218 94.8% 24.41 55.47 36.61 38.83 56.58 42.16 39.94 37.72 49.37 0.15 0.15 0.20 0.39 1.26 Covered/w/another[696]
YCR101C Putative protein of unknown function; localizes to the membrane fraction; YCR101C is not an essential gene Uncharacterized chr3:302479-303027 302479-303027 95.9% 17.09 24.68 26.58 17.09 28.48 34.17 20.88 21.83 31.32 0.08 0.09 0.13 0.52 1.79 Covered/w/another[696]
YCR102C Putative protein of unknown function; involved in copper metabolism; similar to C.carbonum toxD gene; YCR102C is not an essential gene Uncharacterized chr3:304358-305464 304358-305464 45.0% 20.06 12.04 30.10 30.10 28.09 12.04 16.05 30.10 20.06 0.06 0.12 0.08 -0.58 0.09
YCR102W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr3:306732-306929 306732-306929 82.5% 0.00 6.12 0.00 0.00 18.37 6.12 3.06 0.00 12.25 0.01 0.00 0.05 Inf 0.43
YCR104W PAU3 "Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme" Verified chr3:307798-308172 307798-308172 15.4% 34.63 0.00 17.32 17.32 103.90 51.95 17.32 17.32 77.92 0.06 0.07 0.32 2.17 0.92 Frag<80[698]
YCR105W ADH7 NADPH-dependent medium chain alcohol dehydrogenase with broad substrate specificity; member of the cinnamyl family of alcohol dehydrogenases; may be involved in fusel alcohol synthesis or in aldehyde tolerance Verified chr3:309067-310152 309067-310152 98.6% 20.55 17.75 14.01 17.75 38.30 31.76 19.15 15.88 35.03 0.07 0.06 0.15 1.14 1.17 Frag>80[699,700]
YCR106W RDS1 Zinc cluster transcription factor involved in conferring resistance to cycloheximide Verified chr3:310955-313453 310955-313453 81.5% 53.01 41.72 36.81 24.05 17.18 12.27 47.36 30.43 14.72 0.17 0.12 0.06 -1.05 -0.47 Frag<80[701]
YCR107W AAD3 Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role Verified chr3:313887-314978 313887-314978 46.4% 94.75 71.06 51.32 33.56 41.45 13.82 82.91 42.44 27.64 0.31 0.17 0.11 -0.62 -0.81 Overlap[701]
YCR108C Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr3:315994-316185 315994-316185 4.6% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN NaN
YDL248W COS7 "Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr4:1802-2953 1802-2953 14.1% 117.01 153.96 61.59 80.06 178.60 110.85 135.49 70.82 144.73 0.50 0.29 0.60 1.03 0.73 Frag<80[702]
YDL247W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; identified by sequence comparison with hemiascomycetous yeast species" Dubious chr4:3762-3836 3762-3836 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.15
YDL247W MPH2 "Alpha-glucoside permease, transports maltose, maltotriose, alpha-methylglucoside, and turanose; identical to Mph3p; encoded in a subtelomeric position in a region likely to have undergone duplication" Verified chr4:5985-7814 5985-7814 1.2% 0.00 0.00 0.00 0.00 0.00 45.54 0.00 0.00 22.77 0.00 0.00 0.09 Inf 0.58
YDL246C SOR2 "Protein of unknown function, computational analysis of large-scale protein-protein interaction data suggests a possible role in fructose or mannose metabolism" Uncharacterized chr4:8683-9756 8683-9756 0.6% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.35
YDL245C HXT15 "Protein of unknown function with similarity to hexose transporter family members, expression is induced by low levels of glucose and repressed by high levels of glucose" Verified chr4:11657-13360 11657-13360 0.5% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.81
YDL244W THI13 "Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP); member of a subtelomeric gene family including THI5, THI11, THI12, and THI13" Verified chr4:16204-17226 16204-17226 9.4% 10.38 31.13 0.00 0.00 10.38 0.00 20.75 0.00 5.19 0.08 0.00 0.02 Inf 0.30
YDL243C AAD4 "Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase, involved in the oxidative stress response" Verified chr4:17577-18566 17577-18566 37.1% 43.56 54.45 43.56 43.56 70.79 43.56 49.01 43.56 57.18 0.18 0.18 0.24 0.39 0.46 Frag<80[703,704]
YDL242W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr4:18959-19312 18959-19312 98.8% 17.15 22.87 25.72 14.29 14.29 25.72 20.01 20.01 20.01 0.07 0.08 0.08 0.00 0.76
YDL241W Putative protein of unknown function; YDL241W is not an essential gene Uncharacterized chr4:20635-21006 20635-21006 98.6% 114.56 103.65 100.92 95.47 43.64 54.55 109.10 98.19 49.10 0.40 0.40 0.20 -1.00 -0.41 Matched[705]
YDL240C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; identified by sequence comparison with hemiascomycetous yeast species" Dubious chr4:22471-22608 22471-22608 98.8% 0.00 7.33 7.33 0.00 14.67 0.00 3.67 3.67 7.33 0.01 0.01 0.03 1.00 -0.05
YDL240W LRG1 "Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signaling pathway that controls cell wall integrity; appears to specifically regulate 1,3-beta-glucan synthesis" Verified chr4:22823-25876 22823-25876 98.9% 111.60 105.97 109.95 96.37 44.05 36.10 108.79 103.16 40.07 0.40 0.42 0.17 -1.36 -0.74 Matched[706]
YDL239C ADY3 "Protein required for spore wall formation, thought to mediate assembly of a Don1p-containing structure at the leading edge of the prospore membrane via interaction with spindle pole body components; potentially phosphorylated by Cdc28p" Verified chr4:26403-28775 26403-28775 99.4% 70.39 123.83 71.67 55.98 127.22 97.54 97.11 63.82 112.38 0.36 0.26 0.47 0.82 0.70 Covered/w/another[707]
YDL238C GUD1 "Guanine deaminase, a catabolic enzyme of the guanine salvage pathway producing xanthine and ammonia from guanine; activity is low in exponentially-growing cultures but expression is increased in post-diauxic and stationary-phase cultures" Verified chr4:28985-30454 28985-30454 98.9% 57.09 75.66 54.34 60.53 109.36 160.95 66.37 57.43 135.16 0.25 0.23 0.56 1.23 1.49 Covered/w/another[707]
YDL237W Putative protein of unknown function; YDL237W is not an essential gene Uncharacterized chr4:30657-31829 30657-31829 98.9% 320.62 407.67 363.71 365.44 389.57 360.27 364.15 364.58 374.92 1.34 1.48 1.55 0.04 0.72 Matched[708]
YDL236W PHO13 "Alkaline phosphatase specific for p-nitrophenyl phosphate, involved in dephosphorylation of histone II-A and casein" Verified chr4:32296-33234 32296-33234 98.8% 474.33 460.32 470.02 411.80 252.26 168.17 467.32 440.91 210.21 1.73 1.79 0.87 -1.07 -1.01 Matched[709]
YDL235C YPD1 "Phosphorelay intermediate protein, phosphorylated by the plasma membrane sensor Sln1p in response to osmotic stress and then in turn phosphorylates the response regulators Ssk1p in the cytosol and Skn7p in the nucleus" Verified chr4:33415-33918 33415-33918 99.3% 317.76 295.78 321.76 307.77 387.71 253.81 306.77 314.76 320.76 1.13 1.28 1.33 0.03 -0.14 Matched[710]
YDL234C GYP7 "GTPase-activating protein for yeast Rab family members including: Ypt7p (most effective), Ypt1p, Ypt31p, and Ypt32p (in vitro); involved in vesicle mediated protein trafficking" Verified chr4:34238-36478 34238-36478 99.1% 97.70 114.36 106.25 108.95 273.74 194.50 106.03 107.60 234.12 0.39 0.44 0.97 1.12 1.38 Frag>80[711,712]
YDL233W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YDL233W is not an essential gene Uncharacterized chr4:36798-38174 36798-38174 98.8% 50.70 60.99 77.89 53.64 138.15 117.58 55.85 65.77 127.86 0.21 0.27 0.53 0.96 1.68 Matched[713]
YDL232W OST4 "Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes protein asparagine-linked glycosylation; type I membrane protein required for incorporation of Ost3p or Ost6p into the OST complex" Verified chr4:38488-38598 38488-38598 99.3% 798.49 898.30 789.41 789.41 1061.63 725.90 848.39 789.41 893.76 3.13 3.20 3.70 0.18 -0.04 Matched[714]
YDL231C BRE4 "Zinc finger protein containing five transmembrane domains; null mutant exhibits strongly fragmented vacuoles and sensitivity to brefeldin A, a drug which is known to affect intracellular transport" Verified chr4:38868-42245 38868-42245 98.9% 106.83 112.22 73.62 66.73 43.69 46.38 109.52 70.17 45.04 0.40 0.28 0.19 -0.64 -0.43 Frag>80[714,715]
YDL230W PTP1 "Phosphotyrosine-specific protein phosphatase that dephosphorylates a broad range of substrates in vivo, including Fpr3p; localized to the cytoplasm and the mitochondria" Verified chr4:42701-43708 42701-43708 98.5% 111.77 115.80 91.63 99.69 218.50 156.07 113.78 95.66 187.29 0.42 0.39 0.78 0.97 1.23 Matched[716]
YDL229W SSB1 "Cytoplasmic ATPase that is a ribosome-associated molecular chaperone, functions with J-protein partner Zuo1p; may be involved in folding of newly-made polypeptide chains; member of the HSP70 family; interacts with phosphatase subunit Reg1p" Verified chr4:44066-45907 44066-45907 23.9% 7866.14 5173.00 6833.81 5908.11 726.04 471.92 6519.57 6370.96 598.98 24.07 25.86 2.48 -3.41 -3.12 Frag<80[717,718,719]
YDL228C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; almost completely overlaps the verified gene SSB1" Dubious chr4:45278-45919 45278-45919 40.5% 10415.24 6727.07 8709.46 7483.91 1025.77 580.12 8571.15 8096.69 802.95 31.64 32.87 3.33 -3.33 -0.04 Frag>80[718,719]
YDL227C HO "Site-specific endonuclease required for gene conversion at the MAT locus (homothallic switching) through the generation of a ds DNA break; expression restricted to mother cells in late G1 as controlled by Swi4p-Swi6p, Swi5p and Ash1p" Verified chr4:46272-48032 46272-48032 99.2% 252.94 218.60 199.72 107.01 18.88 5.15 235.77 153.37 12.02 0.87 0.62 0.05 -3.67 -3.33 Matched[720]
YDL226C GCS1 "ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Glo3p" Verified chr4:51116-52174 51116-52174 99.0% 448.51 472.37 447.55 383.62 333.04 218.53 460.44 415.59 275.79 1.70 1.69 1.14 -0.59 -0.31 Matched[723]
YDL225W SHS1 "One of five related septins (Cdc3p, Cdc10p, Cdc11p, Cdc12p, Shs1p) that form a cortical filamentous collar at the mother-bud neck which is necessary for normal morphogenesis and cytokinesis" Verified chr4:52446-54101 52446-54101 98.6% 298.80 238.18 243.69 261.45 245.53 186.14 268.49 252.57 215.83 0.99 1.03 0.89 -0.23 0.25 Frag<80[724]
YDL224C WHI4 Putative RNA binding protein and partially redundant Whi3p homolog that regulates the cell size requirement for passage through Start and commitment to cell division Verified chr4:54398-56347 54398-56347 98.8% 239.87 272.06 235.20 215.47 190.03 202.49 255.97 225.33 196.26 0.94 0.91 0.81 -0.20 0.44 Covered[725]
YDL223C HBT1 "Substrate of the Hub1p ubiquitin-like protein that localizes to the shmoo tip (mating projection); mutants are defective for mating projection formation, thereby implicating Hbt1p in polarized cell morphogenesis" Verified chr4:57266-60406 57266-60406 98.9% 42.83 62.47 36.71 28.02 279.52 393.83 52.65 32.36 336.67 0.19 0.13 1.39 3.38 3.75 Covered/w/another[726]
YDL222C FMP45 "Integral membrane protein localized to mitochondria (untagged protein) and eisosomes, immobile patches at the cortex associated with endocytosis; sporulation and sphingolipid content are altered in mutants; has homologs SUR7 and YNL194C" Verified chr4:60873-61802 60873-61802 98.2% 14.23 21.89 13.14 10.95 3285.02 2618.38 18.06 12.04 2951.70 0.07 0.05 12.23 7.94 5.56 Covered/w/another[726]
YDL221W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the 3' end of essential gene CDC13" Dubious chr4:62012-62563 62012-62563 98.2% 60.87 94.07 60.87 33.20 55.33 33.20 77.47 47.03 44.27 0.29 0.19 0.18 -0.09 0.52 Covered/w/another[727]
YDL220C CDC13 "Single stranded DNA-binding protein found at TG1-3 telomere G-tails; regulates telomere replication through recruitment of specific sub-complexes, but the essential function is telomere capping" Verified chr4:62245-65019 62245-65019 98.7% 49.29 45.63 34.32 23.36 27.38 20.44 47.46 28.84 23.91 0.18 0.12 0.10 -0.27 0.06 Frag>80[727,728]
YDL219W DTD1 "D-Tyr-tRNA(Tyr) deacylase, functions in protein translation, may affect nonsense suppression via alteration of the protein synthesis machinery; ubiquitous among eukaryotes" Verified chr4:65243-65766 65243-65307,65379-65766 98.6% 235.10 212.71 241.81 199.27 300.03 183.60 223.90 220.54 241.81 0.83 0.90 1.00 0.13 -0.38 Frag>80[728,729]
YDL218W Putative protein of unknown function; YDL218W transcription is regulated by Azf1p and induced by starvation and aerobic conditions Uncharacterized chr4:66494-67447 66494-67447 98.7% 29.73 23.36 15.93 12.74 41.41 38.23 26.55 14.34 39.82 0.10 0.06 0.16 1.47 1.41 Matched[730]
YDL217C TIM22 Component of the mitochondrial Tim54p-Tim22p complex involved in insertion of polytopic proteins into the inner membrane Verified chr4:67984-68607 67984-68607 99.1% 232.87 163.33 190.82 181.12 119.67 76.01 198.10 185.97 97.84 0.73 0.75 0.41 -0.93 -0.45 Matched[731]
YDL216C RRI1 Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling Verified chr4:68998-70320 68998-70320 99.4% 65.40 67.68 61.60 62.36 104.95 63.12 66.54 61.98 84.04 0.25 0.25 0.35 0.44 0.83 Matched[732]
YDL215C GDH2 "NAD(+)-dependent glutamate dehydrogenase, degrades glutamate to ammonia and alpha-ketoglutarate; expression sensitive to nitrogen catabolite repression and intracellular ammonia levels" Verified chr4:70641-73919 70641-73919 99.1% 140.63 184.33 135.71 117.86 194.18 108.32 162.48 126.78 151.25 0.60 0.51 0.63 0.25 0.14 Matched[733]
YDL214C PRR2 "Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor" Verified chr4:74447-76546 74447-76546 98.9% 13.96 17.33 15.40 9.63 64.97 37.54 15.64 12.51 51.26 0.06 0.05 0.21 2.03 2.41 Matched[734]
YDL213C NOP6 Putative RNA-binding protein implicated in ribosome biogenesis; contains an RNA recognition motif (RRM) and has similarity to hydrophilins; NOP6 may be a fungal-specific gene as no homologs have been yet identified in higher eukaryotes Verified chr4:77290-77967 77290-77967 99.2% 489.01 288.35 389.42 300.24 65.40 69.86 388.68 344.83 67.63 1.43 1.40 0.28 -2.35 -2.09 Matched[735]
YDL212W SHR3 "Endoplasmic reticulum packaging chaperone, required for incorporation of amino acid permeases into COPII coated vesicles for transport to the cell surface" Verified chr4:78427-79059 78427-79059 98.8% 1103.71 1001.33 1068.52 1028.53 454.28 305.52 1052.52 1048.52 379.90 3.89 4.26 1.57 -1.46 -2.14 Matched[736]
YDL211C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole Uncharacterized chr4:79295-80413 79295-80413 98.8% 69.64 66.02 46.12 38.89 23.51 18.09 67.83 42.51 20.80 0.25 0.17 0.09 -1.03 -0.79 Matched[737]
YDL210W UGA4 Permease that serves as a gamma-aminobutyrate (GABA) transport protein involved in the utilization of GABA as a nitrogen source; catalyzes the transport of putrescine and delta-aminolevulinic acid (ALA); localized to the vacuolar membrane Verified chr4:84271-85986 84271-85986 99.0% 11.19 18.26 14.13 5.89 11.78 15.90 14.72 10.01 13.84 0.05 0.04 0.06 0.47 -0.21 Overlap[738]
YDL209C CWC2 "Protein involved in pre-mRNA splicing, component of a complex containing Cef1p; interacts with Prp19p; contains an RNA recognition motif; has similarity to S. pombe Cwf2p" Verified chr4:86208-87227 86208-87227 99.3% 94.78 79.97 87.87 82.93 29.62 17.77 87.38 85.40 23.69 0.32 0.35 0.10 -1.85 -1.58 Covered[738]
YDL208W NHP2 "Nuclear protein related to mammalian high mobility group (HMG) proteins, essential for function of H/ACA-type snoRNPs, which are involved in 18S rRNA processing" Verified chr4:87513-87983 87513-87983 98.5% 2162.61 1403.65 1522.24 1259.19 183.27 105.65 1783.13 1390.71 144.46 6.58 5.65 0.60 -3.27 -3.45 Matched[739]
YDL207W GLE1 Cytoplasmic nucleoporin required for polyadenylated RNA export but not for protein import; component of Nup82p nuclear pore subcomplex; contains a nuclear export signal Verified chr4:88249-89865 88249-89865 98.5% 181.42 183.93 148.15 133.08 103.58 78.47 182.67 140.62 91.02 0.67 0.57 0.38 -0.63 -0.17 Matched[740]
YDL206W Putative protein of unknown function; YDL206W is not an essential protein Uncharacterized chr4:90177-92465 90177-92465 99.1% 50.71 61.29 56.88 48.50 105.38 65.26 56.00 52.69 85.32 0.21 0.21 0.35 0.70 0.53 Matched[741]
YDL205C HEM3 "Phorphobilinogen deaminase, catalyzes the conversion of 4-porphobilinogen to hydroxymethylbilane, the third step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; expression is regulated by Hap2p-Hap3p" Verified chr4:92763-93746 92763-93746 99.0% 431.08 439.29 344.87 344.87 201.17 224.78 435.19 344.87 212.98 1.61 1.40 0.88 -0.70 -0.12 Matched[742]
YDL204W RTN2 Protein of unknown function; has similarity to mammalian reticulon proteins; member of the RTNLA (reticulon-like A) subfamily Verified chr4:94606-95787 94606-95787 98.7% 59.15 226.30 144.01 168.87 3305.38 3840.27 142.72 156.44 3572.83 0.53 0.64 14.80 4.51 3.95 Matched[744]
YDL203C "Putative protein of unknown function; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS; the authentic, non-tagged protein is detected in purified mitochondria" Uncharacterized chr4:96083-97954 96083-97954 99.0% 97.62 93.84 83.06 74.43 56.63 58.25 95.73 78.74 57.44 0.35 0.32 0.24 -0.46 0.14 Matched[745]
YDL202W MRPL11 Mitochondrial ribosomal protein of the large subunit Verified chr4:98476-99225 98476-99225 98.5% 282.81 278.76 290.93 296.35 257.10 185.39 280.78 293.64 221.24 1.04 1.19 0.92 -0.41 -0.13 Matched[746]
YDL201W TRM8 Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p that catalyzes 7-methylguanosine modification of tRNA Verified chr4:99562-100422 99562-100422 98.4% 322.31 175.91 234.95 198.35 36.60 22.43 249.11 216.65 29.52 0.92 0.88 0.12 -2.88 -1.43 Matched[747]
YDL200C MGT1 DNA repair methyltransferase (6-O-methylguanine-DNA methylase) involved in protection against DNA alkylation damage Verified chr4:100502-101068 100502-101068 99.3% 115.47 90.60 119.02 90.60 259.36 99.48 103.03 104.81 179.42 0.38 0.43 0.74 0.78 -0.01 Matched[748]
YDL199C "Putative transporter, member of the sugar porter family" Uncharacterized chr4:101291-103354 101291-103354 98.8% 24.52 48.55 33.84 32.37 100.04 96.12 36.54 33.10 98.08 0.13 0.13 0.41 1.57 2.31 Matched[749]
YDL198C GGC1 "Mitochondrial GTP/GDP transporter, essential for mitochondrial genome maintenance; has a role in mitochondrial iron transport; member of the mitochondrial carrier family" Verified chr4:103650-104552 103650-104552 98.7% 410.45 603.34 379.05 363.35 172.70 131.21 506.89 371.20 151.96 1.87 1.51 0.63 -1.29 -1.19 Matched[750]
YDL197C ASF2 Anti-silencing protein that causes derepression of silent loci when overexpressed Verified chr4:104918-106495 104918-106495 99.0% 131.89 133.81 122.29 103.72 220.89 167.75 132.85 113.01 194.32 0.49 0.46 0.81 0.78 1.23 Matched[751]
YDL196W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; open reading frame is located in promoter region of essential gene SEC31" Dubious chr4:106742-107071 106742-107071 99.0% 18.36 18.36 3.06 6.12 6.12 9.18 18.36 4.59 7.65 0.07 0.02 0.03 0.74 0.81 Overlap[751,752]
YDL195W SEC31 "Essential phosphoprotein component (p150) of the COPII coat of secretory pathway vesicles, in complex with Sec13p; required for ER-derived transport vesicle formation" Verified chr4:107209-111030 107209-111030 98.9% 478.77 426.13 473.74 466.34 387.78 644.35 452.45 470.04 516.06 1.67 1.91 2.14 0.13 1.07 Frag>80[752,753]
YDL194W SNF3 Plasma membrane glucose sensor that regulates glucose transport; has 12 predicted transmembrane segments; long cytoplasmic C-terminal tail is required for low glucose induction of hexose transporter genes HXT2 and HXT4 Verified chr4:111581-114235 111581-114235 98.8% 38.89 51.09 50.71 40.80 55.67 48.42 44.99 45.75 52.04 0.17 0.19 0.22 0.19 0.35 Matched[754]
YDL193W NUS1 "Prenyltransferase, required for cell viability; involved in protein trafficking" Verified chr4:114673-115800 114673-115800 98.6% 205.87 222.05 236.43 210.36 427.01 332.62 213.96 223.40 379.82 0.79 0.91 1.57 0.77 1.07 Matched[755]
YDL192W ARF1 "ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated formation vesicles in intracellular trafficking within the Golgi; functionally interchangeable with Arf2p" Verified chr4:116322-116867 116322-116867 77.3% 5203.79 4281.99 4791.47 4469.19 3561.61 2334.12 4742.89 4630.33 2947.87 17.51 18.80 12.21 -0.65 -2.55 Matched[756]
YDL191W RPL35A "Protein component of the large (60S) ribosomal subunit, identical to Rpl35Bp and has similarity to rat L35 ribosomal protein" Verified chr4:117665-118518 117665-117667,118159-118518 10.5% 3278.69 2596.72 2203.28 2413.11 760.66 393.44 2937.70 2308.20 577.05 10.84 9.37 2.39 -2.00 -2.23 Frag<80[757,758,759]
YDL190C UFD2 "Ubiquitin chain assembly factor (E4) that cooperates with a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), and a ubiquitin protein ligase (E3) to conjugate ubiquitin to substrates; also functions as an E3" Verified chr4:118708-121593 118708-121593 99.0% 190.15 181.39 175.79 190.50 179.64 188.39 185.77 183.14 184.02 0.69 0.74 0.76 0.01 -0.21 Frag>80[759,760]
YDL189W RBS1 "Protein of unknown function, identified as a high copy suppressor of psk1 psk2 mutations that confer temperature-sensitivity for galactose utilization; proposed to bind single-stranded nucleic acids via its R3H domain" Verified chr4:122078-123590 122078-122079,122178-123590 98.6% 255.06 272.26 236.43 180.55 141.14 92.42 263.66 208.49 116.78 0.97 0.85 0.48 -0.84 -0.47 Matched[761]
YDL188C PPH22 "Catalytic subunit of protein phosphatase 2A, functionally redundant with Pph21p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis" Verified chr4:123866-124999 123866-124999 66.1% 278.65 339.98 363.98 291.98 385.31 294.65 309.32 327.98 339.98 1.14 1.33 1.41 0.05 0.34 Frag>80[762,763,764]
YDL186W Putative protein of unknown function; YDL186W is not an essential gene Uncharacterized chr4:125617-126450 125617-126450 98.6% 32.85 64.48 25.55 23.12 57.18 29.20 48.67 24.33 43.19 0.18 0.10 0.18 0.83 0.14 Frag>80[765,766]
YDL187C "Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:125510-125839 125510-125839 98.5% 21.54 30.77 9.23 18.46 6.15 15.39 26.16 13.85 10.77 0.10 0.06 0.04 -0.36 -0.16 Matched[765]
YDL185W TFP1 "Vacuolar ATPase V1 domain subunit A containing the catalytic nucleotide binding sites; protein precursor undergoes self-catalyzed splicing to yield the extein Tfp1p and the intein Vde (PI-SceI), which is a site-specific endonuclease" Verified chr4:126788-130003 126788-130003 98.8% 1581.51 1990.50 1513.50 1555.06 1111.75 1395.11 1786.00 1534.28 1253.43 6.59 6.23 5.19 -0.29 -0.30 Matched[767]
YDL185C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YDL185W; identified by homology with hemiascomycetous yeast species" Dubious chr4:126609-126836 126609-126836 99.0% 385.60 673.68 412.19 491.97 163.99 487.53 529.64 452.08 325.76 1.96 1.84 1.35 -0.47 0.05 Covered/w/another[767]
YDL184C RPL41A "Ribosomal protein L47 of the large (60S) ribosomal subunit, identical to Rpl41Bp and has similarity to rat L41 ribosomal protein; comprised of only 25 amino acids; rpl41a rpl41b double null mutant is viable" Verified chr4:130408-130485 130408-130485 37.5% 9401.71 5709.40 7965.81 6905.98 6393.16 3282.05 7555.56 7435.90 4837.61 27.89 30.18 20.04 -0.62 -2.19 Matched[768]
YDL183C Putative protein of unknown function; YDL183C is not an essential gene Uncharacterized chr4:130872-131834 130872-131834 99.1% 34.59 44.02 38.78 36.68 74.41 52.40 39.30 37.73 63.41 0.15 0.15 0.26 0.75 1.31 Matched[769]
YDL182W LYS20 "Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; highly similar to the other isozyme, Lys21p" Verified chr4:133438-134724 133438-134724 39.4% 565.56 614.83 435.50 258.15 118.24 37.44 590.20 346.83 77.84 2.18 1.41 0.32 -2.16 -1.60 Frag<80[770,771,772,773]
YDL181W INH1 "Protein that inhibits ATP hydrolysis by the F1F0-ATP synthase, inhibitory function is enhanced by stabilizing proteins Stf1p and Stf2p; has similarity to Stf1p and both Inh1p and Stf1p exhibit the potential to form coiled-coil structures" Verified chr4:135180-135437 135180-135437 98.2% 426.46 529.12 647.58 742.35 1476.80 872.66 477.79 694.97 1174.73 1.76 2.82 4.87 0.76 0.50 Matched[774]
YDL180W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole Uncharacterized chr4:135897-137540 135897-137540 99.0% 109.39 115.54 105.09 92.18 122.91 90.96 112.47 98.64 106.93 0.42 0.40 0.44 0.12 0.61 Matched[775]
YDL179W PCL9 "Cyclin, forms a functional kinase complex with Pho85p cyclin-dependent kinase (Cdk), expressed in late M/early G1 phase, activated by Swi5p" Verified chr4:138292-139206 138292-139206 99.1% 124.65 145.61 138.99 113.62 163.26 91.56 135.13 126.30 127.41 0.50 0.51 0.53 0.01 0.52 Frag>80[776,777]
YDL178W DLD2 "D-lactate dehydrogenase, located in the mitochondrial matrix" Verified chr4:139523-141115 139523-141115 98.4% 357.36 308.86 346.51 364.38 232.28 150.60 333.11 355.45 191.44 1.23 1.44 0.79 -0.89 -0.70 Matched[778]
YDL177C Putative protein of unknown function; similar to the mouse IMPACT gene; YDL177C is not an essential gene Uncharacterized chr4:141210-141722 141210-141722 99.3% 92.22 107.92 113.81 58.87 117.73 78.49 100.07 86.34 98.11 0.37 0.35 0.41 0.18 0.06 Matched[779]
YDL176W Putative protein of unknown function; YDL176W is not an essential gene Uncharacterized chr4:142098-144224 142098-144224 98.9% 69.44 87.99 61.35 47.09 52.79 36.62 78.71 54.22 44.71 0.29 0.22 0.19 -0.28 -0.17 Covered/w/another[780]
YDL175C AIR2 "RING finger protein that interacts with the arginine methyltransferase Hmt1p; may regulate methylation of Npl3p, which modulates Npl3p function in mRNA processing and export; has similarity to Air1p" Verified chr4:144485-145519 144485-145519 98.9% 112.34 107.45 79.12 61.54 99.64 65.45 109.89 70.33 82.54 0.41 0.29 0.34 0.23 0.67 Covered/w/another[780]
YDL174C DLD1 "D-lactate dehydrogenase, oxidizes D-lactate to pyruvate, transcription is heme-dependent, repressed by glucose, and derepressed in ethanol or lactate; located in the mitochondrial inner membrane" Verified chr4:145827-147590 145827-147590 98.9% 264.20 289.99 397.16 346.16 365.07 297.44 277.10 371.66 331.26 1.02 1.51 1.37 -0.17 0.39 Matched[781]
YDL173W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YDL173W is not an essential gene Uncharacterized chr4:148192-149079 148192-149079 98.3% 444.36 477.57 408.86 388.24 489.02 463.83 460.97 398.55 476.43 1.70 1.62 1.97 0.26 0.06 Matched[783]
YDL172C "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr4:148608-149087 148608-149087 98.2% 507.16 522.02 451.99 460.48 534.75 485.94 514.59 456.23 510.34 1.90 1.85 2.11 0.16 0.11 Matched[783]
YDL171C GLT1 "NAD(+)-dependent glutamate synthase (GOGAT), synthesizes glutamate from glutamine and alpha-ketoglutarate; with Gln1p, forms the secondary pathway for glutamate biosynthesis from ammonia; expression regulated by nitrogen source" Verified chr4:149204-155641 149204-155641 99.1% 265.95 294.01 245.27 213.92 43.88 67.70 279.98 229.59 55.79 1.03 0.93 0.23 -2.04 -1.00 Matched[784]
YDL170W UGA3 "Transcriptional activator necessary for gamma-aminobutyrate (GABA)-dependent induction of GABA genes (such as UGA1, UGA2, UGA4); zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type; localized to the nucleus" Verified chr4:156319-157905 156319-157905 98.8% 83.57 167.77 57.41 48.48 61.88 74.64 125.67 52.95 68.26 0.46 0.21 0.28 0.37 0.94 Covered/w/another[785]
YDL169C UGX2 "Protein of unknown function, transcript accumulates in response to any combination of stress conditions" Verified chr4:158065-158736 158065-158736 99.3% 37.46 70.43 53.95 62.94 209.79 127.37 53.95 58.44 168.58 0.20 0.24 0.70 1.53 1.47 Covered/w/another[785]
YDL168W SFA1 "Bifunctional enzyme containing both alcohol dehydrogenase and glutathione-dependent formaldehyde dehydrogenase activities, functions in formaldehyde detoxification and formation of long chain and complex alcohols, regulated by Hog1p-Sko1p" Verified chr4:159605-160765 159605-160765 98.6% 233.26 160.75 249.86 215.79 298.79 243.75 197.01 232.83 271.27 0.73 0.95 1.12 0.22 0.58 Frag>80[786,787]
YDL167C NRP1 "Protein of unknown function, rich in asparagine residues" Verified chr4:160996-163155 160996-163155 99.2% 199.81 125.58 118.58 88.23 11.20 2.80 162.69 103.40 7.00 0.60 0.42 0.03 -3.88 -2.27 Matched[788]
YDL166C FAP7 "Essential NTPase required for small ribosome subunit synthesis, mediates processing of the 20S pre-rRNA at site D in the cytoplasm but associates only transiently with 43S preribosomes via Rps14p, may be the endonuclease for site D" Verified chr4:163450-164043 163450-164043 99.4% 291.38 196.51 210.07 198.21 89.79 55.90 243.95 204.14 72.85 0.90 0.83 0.30 -1.49 -1.68 Matched[789]
YDL165W CDC36 "Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation; basal transcription factor" Verified chr4:164291-164866 164291-164866 98.6% 262.36 246.52 244.75 258.84 295.82 117.98 254.44 251.80 206.90 0.94 1.02 0.86 -0.28 -0.57 Covered/w/another[790]
YDL163W "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the verified gene CDC9/YDL164C encoding DNA ligase" Dubious chr4:166957-167259 166957-167259 98.6% 50.22 103.79 53.57 46.88 20.09 30.13 77.01 50.22 25.11 0.28 0.20 0.10 -1.00 -0.06 Covered/w/another[790]
YDL164C CDC9 "DNA ligase found in the nucleus and mitochondria, an essential enzyme that joins Okazaki fragments during DNA replication; also acts in nucleotide excision repair, base excision repair, and recombination" Verified chr4:164988-167255 164988-167255 99.1% 150.42 117.93 121.94 110.81 62.30 52.51 134.18 116.38 57.41 0.50 0.47 0.24 -1.02 -0.54 Matched[790]
YDL161W ENT1 Epsin-like protein involved in endocytosis and actin patch assembly and functionally redundant with Ent2p; binds clathrin via a clathrin-binding domain motif at C-terminus Verified chr4:167715-169079 167715-169079 98.4% 238.14 191.26 174.88 204.65 206.14 169.67 214.70 189.77 187.91 0.79 0.77 0.78 -0.01 0.58 Covered/w/another[791]
YDL162C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps ENT1/YDL161W, a verified gene involved in endocytosis and actin cortical patch assembly" Dubious chr4:167360-167716 167360-167716 98.0% 8.57 0.00 14.29 2.86 14.29 5.71 4.29 8.57 10.00 0.02 0.03 0.04 0.22 0.58 Overlap[790,791]
YDL160C-A Putative protein of unknown function Uncharacterized chr4:169367-169609 169367-169609 99.4% 215.25 169.71 186.27 165.57 157.30 99.34 192.48 175.92 128.32 0.71 0.71 0.53 -0.46 NaN Covered/w/another[791]
YDL160C DHH1 "Cytoplasmic DExD/H-box helicase, stimulates mRNA decapping, coordinates distinct steps in mRNA function and decay, interacts with both the decapping and deadenylase complexes, may have a role in mRNA export and translation" Verified chr4:170411-171931 170411-171931 99.0% 528.12 495.57 506.86 514.84 580.60 646.37 511.85 510.85 613.49 1.89 2.07 2.54 0.26 0.60 Matched[792]
YDL159W-A Putative protein of unknown function; identified by sequence comparison with hemiascomycetous yeast species Uncharacterized chr4:172183-172314 172183-172314 99.8% 60.74 106.30 98.70 83.52 60.74 75.93 83.52 91.11 68.33 0.31 0.37 0.28 -0.42 0.41 Covered/w/another[792]
YDL159W STE7 "Signal transducing MAP kinase kinase involved in pheromone response, where it phosphorylates Fus3p, and in the pseudohyphal/invasive growth pathway, through phosphorylation of Kss1p; phosphorylated by Ste11p, degraded by ubiquitin pathway" Verified chr4:172482-174029 172482-174029 98.8% 68.62 70.58 58.82 56.20 98.68 77.12 69.60 57.51 87.90 0.26 0.23 0.36 0.61 0.12 Matched[793]
YDL159C-B "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr4:173057-173233 173057-173233 99.2% 68.36 56.97 28.48 62.66 96.84 74.06 62.66 45.57 85.45 0.23 0.18 0.35 0.91 NaN Matched[793]
YDL158C "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr4:173867-174175 173867-174175 99.1% 221.98 254.62 238.30 189.34 173.01 127.31 238.30 213.82 150.16 0.88 0.87 0.62 -0.51 -1.81 Frag<80[794]
YDL157C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr4:174233-174589 174233-174589 99.1% 647.12 480.40 534.09 519.96 415.40 327.80 563.76 527.02 371.60 2.08 2.14 1.54 -0.50 -0.91 Matched[794]
YDL156W Putative protein of unknown function; protein sequence contains three WD domains (WD-40 repeat); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus Uncharacterized chr4:174919-176487 174919-176487 98.5% 69.90 62.13 62.13 60.19 21.36 40.77 66.01 61.16 31.06 0.24 0.25 0.13 -0.98 0.13 Covered/w/another[795]
YDL155W CLB3 "B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation" Verified chr4:176774-178057 176774-178057 98.6% 214.89 191.19 218.05 191.19 160.38 121.67 203.04 204.62 141.02 0.75 0.83 0.58 -0.54 -0.25 Covered/w/another[795]
YDL154W MSH5 "Protein of the MutS family, forms a dimer with Msh4p that facilitates crossovers between homologs during meiosis; msh5-Y823H mutation confers tolerance to DNA alkylating agents; homologs present in C. elegans and humans" Verified chr4:178335-181040 178335-181040 98.7% 46.80 45.67 29.95 37.44 59.15 29.95 46.24 33.69 44.55 0.17 0.14 0.18 0.40 0.08 Frag<80[796]
YDL152W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF SAS10/YDL153C, a component of the small ribosomal subunit processosome" Dubious chr4:182823-183188 182823-183188 99.1% 129.63 52.40 71.71 71.71 2.76 0.00 91.01 71.71 1.38 0.34 0.29 0.01 -5.70 -0.15 Overlap[797]
YDL153C SAS10 "Component of the small (ribosomal) subunit (SSU) processosome required for pre-18S rRNa processing; essential nucleolar protein that, when overproduced, disrupts silencing" Verified chr4:181187-183019 181187-183019 99.5% 309.79 125.56 188.07 185.33 21.93 4.39 217.68 186.70 13.16 0.80 0.76 0.05 -3.83 -2.50 Matched[797]
YDL150W RPC53 RNA polymerase III subunit C53 Verified chr4:183344-184612 183344-184612 98.0% 255.60 164.77 178.44 134.23 36.97 15.27 210.19 156.33 26.12 0.78 0.63 0.11 -2.58 -0.89 Matched[798]
YDL151C BUD30 "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 96% of ORF overlaps the verified gene RPC53; diploid mutant displays a weak budding pattern phenotype in a systematic assay" Dubious chr4:183319-183900 183319-183900 97.7% 232.17 130.16 154.78 109.05 24.62 5.28 181.17 131.92 14.95 0.67 0.54 0.06 -3.14 -0.42 Covered/w/another[798]
YDL149W ATG9 "Transmembrane protein involved in formation of Cvt and autophagic vesicles; cycles between the pre-autophagosomal structure and other cytosolic punctate structures, not found in autophagosomes" Verified chr4:184926-187919 184926-187919 98.8% 36.83 53.05 37.85 41.56 62.52 70.63 44.94 39.71 66.57 0.17 0.16 0.28 0.75 1.01 Matched[799]
YDL148C NOP14 "Nucleolar protein, forms a complex with Noc4p that mediates maturation and nuclear export of 40S ribosomal subunits; also present in the small subunit processome complex, which is required for processing of pre-18S rRNA" Verified chr4:188155-190587 188155-190587 99.3% 288.78 131.15 188.24 152.25 15.72 4.14 209.96 170.25 9.93 0.78 0.69 0.04 -4.10 -3.63 Matched[800]
YDL147W RPN5 "Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to mammalian p55 subunit and to another S. cerevisiae regulatory subunit, Rpn7p" Verified chr4:190925-192262 190925-192262 98.8% 687.66 597.64 655.89 651.35 1265.63 845.77 642.65 653.62 1055.70 2.37 2.65 4.37 0.69 0.55 Matched[801]
YDL146W LDB17 "Protein of unknown function; GFP-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; null mutant shows a reduced affinity for the alcian blue dye suggesting a decreased net negative charge of the cell surface" Verified chr4:192751-194226 192751-194226 99.0% 102.62 140.25 120.41 79.36 251.77 134.09 121.44 99.89 192.93 0.45 0.41 0.80 0.95 1.10 Matched[802]
YDL145C COP1 "Alpha subunit of COPI vesicle coatomer complex, which surrounds transport vesicles in the early secretory pathway" Verified chr4:194572-198177 194572-198177 99.0% 766.68 688.25 727.19 678.73 334.74 419.34 727.47 702.96 377.04 2.69 2.85 1.56 -0.90 -0.38 Frag>80[803,804,805]
YDL144C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YDL144C is not an essential gene. Uncharacterized chr4:198663-199733 198663-199733 98.8% 119.06 132.29 132.29 125.67 251.35 168.20 125.67 128.98 209.77 0.46 0.52 0.87 0.70 0.76 Matched[806]
YDL143W CCT4 "Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo" Verified chr4:199997-201583 199997-201583 98.6% 703.44 468.96 634.44 575.02 391.65 322.01 586.20 604.73 356.83 2.16 2.45 1.48 -0.76 -0.45 Matched[807]
YDL142C CRD1 "Cardiolipin synthase; produces cardiolipin, which is an important constituent of mitochondrial membranes; required for normal mitochondrial membrane potential and function" Verified chr4:201720-202571 201720-202571 99.0% 81.83 103.18 90.13 124.52 269.21 126.90 92.50 107.33 198.05 0.34 0.44 0.82 0.88 0.85 Frag>80[808,809]
YDL141W BPL1 "Biotin:apoprotein ligase, covalently modifies proteins with the addition of biotin, required for acetyl-CoA carboxylase (Acc1p) holoenzyme formation" Verified chr4:203040-205112 203040-205112 98.9% 114.62 100.48 110.23 83.90 74.63 72.19 107.55 97.07 73.41 0.40 0.39 0.30 -0.40 0.03 Matched[810]
YDL140C RPO21 "RNA polymerase II largest subunit B220, part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime" Verified chr4:205361-210562 205361-210562 97.5% 379.27 319.71 345.75 311.23 159.36 307.29 349.49 328.49 233.32 1.29 1.33 0.97 -0.49 0.45 Frag<80[811]
YDL139C SCM3 "Nonhistone component of centromeric chromatin that binds stoichiometrically to CenH3-H4 histones, required for kinetochore assembly; contains nuclear export signal (NES); required for G2/M progression and localization of Cse4p" Verified chr4:211376-212047 211376-212047 99.4% 53.91 46.42 52.41 40.43 46.42 49.41 50.16 46.42 47.92 0.19 0.19 0.20 0.05 0.66 Covered[812]
YDL138W RGT2 "Plasma membrane glucose receptor, highly similar to Snf3p; both Rgt2p and Snf3p serve as transmembrane glucose sensors generating an intracellular signal that induces expression of glucose transporter (HXT) genes" Verified chr4:213352-215643 213352-215643 98.8% 71.54 80.81 54.76 38.42 59.61 59.61 76.17 46.59 59.61 0.28 0.19 0.25 0.36 1.05 Matched[813]
YDL137W ARF2 "ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated formation vesicles in intracellular trafficking within the Golgi; functionally interchangeable with Arf1p" Verified chr4:216157-217074 216157-216158,216490-217074 80.2% 2642.59 2597.98 2653.21 2547.00 3602.76 2215.61 2620.29 2600.11 2909.19 9.67 10.55 12.05 0.16 -1.93 Frag>80[814,815]
YDL136W RPL35B "Protein component of the large (60S) ribosomal subunit, identical to Rpl35Ap and has similarity to rat L35 ribosomal protein" Verified chr4:217600-218367 217600-217602,218008-218367 10.5% 2434.02 1465.65 1387.13 1046.89 444.93 183.21 1949.84 1217.01 314.07 7.20 4.94 1.30 -1.95 -2.17 Frag<80[816,817]
YDL135C RDI1 Rho GDP dissociation inhibitor involved in the localization and regulation of Cdc42p Verified chr4:218680-219288 218680-219288 99.5% 369.76 425.89 430.84 368.11 614.07 343.35 397.83 399.48 478.71 1.47 1.62 1.98 0.26 -0.26 Matched[818]
YDL134C PPH21 "Catalytic subunit of protein phosphatase 2A, functionally redundant with Pph22p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis" Verified chr4:219662-220771 219662-220771 66.9% 577.49 584.22 512.87 526.33 660.95 368.84 580.85 519.60 514.89 2.14 2.11 2.13 -0.01 0.08 Frag>80[819,820]
YDL133C-A RPL41B "Ribosomal protein L47 of the large (60S) ribosomal subunit, identical to Rpl41Ap and has similarity to rat L41 ribosomal protein; comprised of only 25 amino acids; rpl41a rpl41b double null mutant is viable" Verified chr4:221724-221801 221724-221801 38.0% 11341.77 9282.70 7864.98 7696.20 8438.82 7291.14 10312.24 7780.59 7864.98 38.07 31.58 32.59 0.02 -1.63 Matched[821]
YDL133W Putative protein of unknown function Uncharacterized chr4:222427-223740 222427-223740 98.8% 130.95 150.97 143.27 146.35 174.08 124.78 140.96 144.81 149.43 0.52 0.59 0.62 0.05 0.02 Matched[822]
YDL132W CDC53 "Cullin, structural protein of SCF complexes (which also contain Skp1p, Cdc34p, Hrt1p and an F-box protein) involved in ubiquitination; SCF promotes the G1-S transition by targeting G1 cyclins and the Cln-CDK inhibitor Sic1p for degradation" Verified chr4:224304-226751 224304-226751 98.8% 224.59 217.15 221.28 208.88 308.56 230.38 220.87 215.08 269.47 0.82 0.87 1.12 0.33 0.56 Frag>80[823,824]
YDL131W LYS21 "Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; highly similar to the other isozyme, Lys20p" Verified chr4:227393-228715 227393-228715 40.9% 411.95 672.41 380.54 288.18 133.00 103.45 542.18 334.36 118.23 2.00 1.36 0.49 -1.50 -0.98 Frag<80[825,826,827,828]
YDL130W-A STF1 Protein involved in regulation of the mitochondrial F1F0-ATP synthase; Stf1p and Stf2p act as stabilizing factors that enhance inhibitory action of the Inh1p protein Verified chr4:229171-229431 229171-229431 98.5% 711.60 1287.10 1166.56 1267.66 4382.37 2340.89 999.35 1217.11 3361.63 3.69 4.94 13.93 1.47 0.99 Matched[829]
YDL130W RPP1B "Ribosomal protein P1 beta, component of the ribosomal stalk, which is involved in interaction of translational elongation factors with ribosome; accumulation is regulated by phosphorylation and interaction with the P2 stalk component" Verified chr4:229906-230527 229906-230019,230321-230527 90.1% 8181.03 7084.46 7745.17 6216.20 2763.91 1916.40 7632.75 6980.69 2340.16 28.18 28.34 9.70 -1.58 -2.48 Matched[830]
YDL129W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus; YDL129W is not an essential gene Uncharacterized chr4:231024-231899 231024-231899 98.4% 37.14 38.30 32.49 33.65 27.85 16.25 37.72 33.07 22.05 0.14 0.13 0.09 -0.58 -0.31 Matched[831]
YDL128W VCX1 "Vacuolar H+/Ca2+ exchanger involved in control of cytosolic Ca2+ concentration; has similarity to sodium/calcium exchangers, including the bovine Na+/Ca2+,K+ antiporter" Verified chr4:232652-233887 232652-233887 98.9% 478.59 413.96 415.60 404.15 373.88 249.52 446.28 409.87 311.70 1.65 1.66 1.29 -0.40 -0.12 Matched[832]
YDL127W PCL2 "G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to entry into the mitotic cell cycle, essential for cell morphogenesis; localizes to sites of polarized cell growth" Verified chr4:234927-235853 234927-235853 99.1% 109.97 138.28 103.44 91.46 84.93 43.55 124.13 97.45 64.24 0.46 0.40 0.27 -0.60 -0.95 Matched[833]
YDL126C CDC48 "ATPase in ER, nuclear membrane and cytosol with homology to mammalian p97; in a complex with Npl4p and Ufd1p participates in retrotranslocation of ubiquitinated proteins from the ER into the cytosol for degradation by the proteasome" Verified chr4:236157-238664 236157-238664 99.0% 1187.03 952.69 1181.40 1182.61 1495.87 1300.18 1069.86 1182.00 1398.03 3.95 4.80 5.79 0.24 0.24 Frag>80[834,835,836]
YDL125C HNT1 "Adenosine 5'-monophosphoramidase; interacts physically and genetically with Kin28p, a CDK and TFIIK subunit, and genetically with CAK1; member of the histidine triad (HIT) superfamily of nucleotide-binding proteins and similar to Hint" Verified chr4:239019-239606 239019-239398,239510-239606 98.7% 1101.91 1176.22 1053.08 944.80 2070.06 934.18 1139.07 998.94 1502.12 4.20 4.05 6.22 0.59 -0.00 Frag>80[836,837,838]
YDL124W "NADPH-dependent alpha-keto amide reductase; reduces aromatic alpha-keto amides, aliphatic alpha-keto esters, and aromatic alpha-keto esters; member of the aldo-keto reductase (AKR) family" Verified chr4:240259-241197 240259-241197 98.7% 862.31 1414.88 1087.87 1014.48 5240.76 3809.70 1138.59 1051.17 4525.23 4.20 4.27 18.75 2.11 1.67 Matched[839]
YDL123W SNA4 "Protein of unknown function, localized to the vacuolar outer membrane" Verified chr4:241418-241840 241418-241840 98.9% 181.67 241.43 224.70 162.55 260.56 169.72 211.55 193.63 215.14 0.78 0.79 0.89 0.15 0.42 Covered/w/another[840]
YDL122W UBP1 Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins; cleaves at the C terminus of ubiquitin fusions irrespective of their size; capable of cleaving polyubiquitin chains Verified chr4:242552-244981 242552-244981 98.6% 267.45 198.61 251.18 207.37 94.71 84.28 233.03 229.28 89.50 0.86 0.93 0.37 -1.36 -0.75 Covered/w/another[840]
YDL121C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic retiuculum; YDL121C is not an essential protein Uncharacterized chr4:245133-245582 245133-245582 99.2% 367.54 266.69 340.65 304.79 40.34 20.17 317.12 322.72 30.25 1.17 1.31 0.13 -3.42 -3.35 Covered/w/another[840]
YDL120W YFH1 "Frataxin, regulates mitochondrial iron accumulation; interacts with Isu1p which promotes Fe-S cluster assembly; interacts with electron transport chain components and may influence respiration; human homolog involved in Friedrich's ataxia" Verified chr4:245923-246447 245923-246447 98.7% 308.93 426.71 349.48 256.80 283.83 202.74 367.82 303.14 243.28 1.36 1.23 1.01 -0.32 -0.29 Matched[841]
YDL118W "Non-essential protein of unconfirmed function; mutants are defective in telomere maintenance, and are synthetically sick or lethal with alpha-synuclein" Uncharacterized chr4:247302-247682 247302-247682 99.2% 50.29 50.29 87.34 74.11 145.57 82.05 50.29 80.72 113.81 0.19 0.33 0.47 0.50 0.17 Covered/w/another[842]
YDL119C "Putative mitochondrial transport protein; GFP-fusion protein is induced in response to the DNA-damaging agent MMS; the authentic, non-tagged protein is detected in purified mitochondria" Uncharacterized chr4:246689-247612 246689-247612 99.1% 81.94 86.31 79.76 63.37 198.84 100.51 84.13 71.56 149.68 0.31 0.29 0.62 1.06 0.49 Matched[842]
YDL117W CYK3 SH3-domain protein located in the mother-bud neck and the cytokinetic actin ring; mutant phenotype and genetic interactions suggest a role in cytokinesis Verified chr4:248581-251238 248581-251238 98.8% 119.22 97.89 105.88 84.17 96.36 76.56 108.55 95.03 86.46 0.40 0.39 0.36 -0.14 0.60 Matched[843]
YDL116W NUP84 "Subunit of the nuclear pore complex (NPC), forms a subcomplex with Nup85p, Nup120p, Nup145p-C, Sec13p, and Seh1p that plays a role in nuclear mRNA export and NPC biogenesis" Verified chr4:251566-253746 251566-253746 98.9% 173.45 153.97 140.52 145.16 121.04 93.68 163.71 142.84 107.36 0.60 0.58 0.44 -0.41 0.14 Matched[844]
YDL114W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; identified based on homology to hemiascomycetous yeasts" Dubious chr4:254935-255048 254935-255048 99.6% 35.23 26.42 35.23 70.46 88.07 70.46 30.83 52.84 79.27 0.11 0.21 0.33 0.58 0.06 Matched[846]
YDL115C IWR1 "Protein of unknown function, deletion causes hypersensitivity to the K1 killer toxin" Verified chr4:253995-255126 253995-254974,255045-255126 99.4% 168.61 166.72 140.20 147.77 359.01 197.03 167.67 143.98 278.02 0.62 0.58 1.15 0.95 0.53 Frag>80[845,846]
YDL114W Putative protein of unknown function with similarity to acyl-carrier-protein reductases; YDL114W is not an essential gene Uncharacterized chr4:255604-256530 255604-256530 99.0% 2.18 4.36 0.00 1.09 8.72 1.09 3.27 0.54 4.90 0.01 0.00 0.02 3.17 1.39 Frag<80[847]
YDL113C ATG20 "Protein required for transport of aminopeptidase I (Lap4p) through the cytoplasm-to-vacuole targeting pathway; binds phosphatidylinositol-3-phosphate, involved in localization of membranes to the preautophagosome, potential Cdc28p substrate" Verified chr4:256633-258555 256633-258555 99.3% 88.49 107.34 108.38 99.48 205.77 152.37 97.91 103.93 179.07 0.36 0.42 0.74 0.78 1.07 Frag>80[847,848]
YDL112W TRM3 "2'-O-ribose methyltransferase, catalyzes the ribose methylation of the guanosine nucleotide at position 18 of tRNAs" Verified chr4:258915-263225 258915-263225 98.9% 132.25 80.43 94.26 82.54 16.41 10.55 106.34 88.40 13.48 0.39 0.36 0.06 -2.71 -2.01 Matched[849]
YDL111C RRP42 "Protein involved in rRNA processing; component of the exosome 3->5 exonuclease complex with Rrp4p, Rrp41p, Rrp43p and Dis3p" Verified chr4:263313-264110 263313-264110 98.9% 226.86 178.70 204.04 179.97 191.37 128.00 202.78 192.01 159.69 0.75 0.78 0.66 -0.27 -0.23 Matched[850]
YDL110C TMA17 Protein of unknown function that associates with ribosomes Verified chr4:264512-264964 264512-264964 99.3% 473.33 973.33 951.11 946.67 3891.11 2660.00 723.33 948.89 3275.56 2.67 3.85 13.57 1.79 1.17 Matched[851]
YDL109C Putative lipase; involved in lipid metabolism; YDL109C is not an essential gene Uncharacterized chr4:265258-267201 265258-267201 98.9% 31.71 48.35 34.83 22.36 46.79 45.23 40.03 28.59 46.01 0.15 0.12 0.19 0.69 1.20 Matched[852]
YDL108W KIN28 "Serine/threonine protein kinase, subunit of the transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters" Verified chr4:267698-268699 267698-267725,267807-268699 98.8% 104.42 109.92 82.44 84.63 116.51 56.06 107.17 83.54 86.28 0.40 0.34 0.36 0.05 0.15 Covered/w/another[853]
YDL107W MSS2 "Peripherally bound inner membrane protein of the mitochondrial matrix, binds to the Cox2p C-terminal tail to facilitate its translocation through the inner membrane" Verified chr4:268921-269976 268921-269976 98.7% 80.56 95.90 82.48 70.97 124.68 77.68 88.23 76.72 101.18 0.33 0.31 0.42 0.40 0.41 Covered/w/another[853]
YDL106C PHO2 Homeobox transcription factor; regulatory targets include genes involved in phosphate metabolism; binds cooperatively with Pho4p to the PHO5 promoter; phosphorylation of Pho2p facilitates interaction with Pho4p Verified chr4:270222-271901 270222-271901 99.2% 103.17 117.57 100.77 103.17 164.95 110.97 110.37 101.97 137.96 0.41 0.41 0.57 0.44 0.84 Covered/w/another[853]
YDL105W NSE4 Nuclear protein that plays a role in the function of the Smc5p-Rhc18p complex Verified chr4:272389-273597 272389-273597 98.6% 80.55 67.96 55.38 52.86 41.11 32.72 74.26 54.12 36.92 0.27 0.22 0.15 -0.55 -0.21 Covered/w/another[854]
YDL104C QRI7 "Putative metalloprotease, similar to O-sialoglycoprotein metallopeptidase from P. haemolytica; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr4:273653-274876 273653-274876 99.2% 63.39 63.39 52.68 55.98 62.56 32.10 63.39 54.33 47.33 0.23 0.22 0.20 -0.20 -0.47 Covered/w/another[854]
YDL103C QRI1 "UDP-N-acetylglucosamine pyrophosphorylase, catalyzes the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is important in cell wall biosynthesis, protein N-glycosylation, and GPI anchor biosynthesis" Verified chr4:275148-276581 275148-276581 99.2% 264.39 238.37 271.42 255.24 293.21 207.43 251.38 263.33 250.32 0.93 1.07 1.04 -0.07 0.28 Matched[855]
YDL102W POL3 "Catalytic subunit of DNA polymerase delta; required for chromosomal DNA replication during mitosis and meiosis, intragenic recombination, repair of double strand DNA breaks, and DNA replication during nucleotide excision repair (NER)" Verified chr4:276872-280165 276872-280165 98.9% 80.15 52.82 69.09 51.90 30.09 24.26 66.48 60.49 27.18 0.25 0.25 0.11 -1.15 -0.61 Matched[856]
YDL101C DUN1 "Cell-cycle checkpoint serine-threonine kinase required for DNA damage-induced transcription of certain target genes, phosphorylation of Rad55p and Sml1p, and transient G2/M arrest after DNA damage; also regulates postreplicative DNA repair" Verified chr4:280307-281848 280307-281848 99.2% 110.50 102.66 119.00 98.73 181.12 139.27 106.58 108.87 160.20 0.39 0.44 0.66 0.56 0.48 Matched[857]
YDL100C GET3 "ATPase, subunit of the GET complex; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion; involved in resistance to heat and metal stress" Verified chr4:282112-283176 282112-283176 99.1% 937.44 814.22 836.97 802.84 1123.22 752.61 875.83 819.91 937.91 3.23 3.33 3.89 0.19 0.39 Matched[858]
YDL099W BUG1 "Cis-golgi localized protein involved in ER to Golgi transport; forms a complex with the mammalian GRASP65 homolog, Grh1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes" Verified chr4:283419-284444 283419-284444 98.2% 416.02 412.05 353.47 353.47 552.04 395.17 414.03 353.47 473.61 1.53 1.43 1.96 0.42 0.46 Frag>80[859,860]
YDL098C SNU23 Component of U4/U6.U5 snRNP involved in mRNA splicing via spliceosome Verified chr4:284581-285165 284581-285165 99.5% 63.57 61.86 72.16 54.98 96.22 58.42 62.71 63.57 77.32 0.23 0.26 0.32 0.28 0.11 Matched[860]
YDL097C RPN6 "Essential, non-ATPase regulatory subunit of the 26S proteasome lid required for the assembly and activity of the 26S proteasome; the human homolog (S9 protein) partially rescues Rpn6p depletion" Verified chr4:285391-286695 285391-286695 99.1% 518.73 455.34 565.89 494.77 902.17 650.93 487.03 530.33 776.55 1.80 2.15 3.22 0.55 0.86 Frag>80[861,862]
YDL095W PMT1 "Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt2p, can instead interact with Pmt3p in some conditions; target for new antifungals" Verified chr4:287059-289512 287059-289512 98.9% 685.46 583.71 655.80 596.89 515.74 551.58 634.58 626.34 533.66 2.34 2.54 2.21 -0.23 0.21 Matched[863]
YDL096C OPI6 "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene PMT1/YDL095W; YDL096C is not essential" Dubious chr4:286998-287324 286998-287324 98.4% 276.68 251.81 313.99 279.79 152.33 307.77 264.25 296.89 230.05 0.98 1.21 0.95 -0.37 -0.12 Covered/w/another[863]
YDL093W PMT5 "Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt3p, can instead interact with Pmt2p in some conditions; target for new antifungals" Verified chr4:289909-292140 289909-292140 99.0% 104.55 130.34 104.09 102.74 55.22 50.69 117.45 103.42 52.95 0.43 0.42 0.22 -0.97 -0.44 Matched[864]
YDL094C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verfied gene PMT5/YDL093W; YDL094C is not essential" Dubious chr4:289572-290081 289572-290081 99.1% 73.23 71.25 39.58 65.31 49.48 47.50 72.24 52.44 48.49 0.27 0.21 0.20 -0.11 0.23 Covered/w/another[864]
YDL092W SRP14 "Signal recognition particle (SRP) subunit, interacts with the RNA component of SRP to form the Alu domain, which is the region of SRP responsible for arrest of nascent chain elongation during membrane targeting; homolog of mammalian SRP14" Verified chr4:292781-293221 292781-293221 98.4% 566.66 497.55 573.57 486.04 490.64 304.06 532.10 529.80 397.35 1.96 2.15 1.65 -0.42 -0.52 Matched[865]
YDL091C UBX3 "UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p, green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" Verified chr4:293392-294759 293392-294759 99.2% 111.97 151.75 134.81 140.70 166.49 119.34 131.86 137.76 142.91 0.49 0.56 0.59 0.05 0.47 Matched[866]
YDL090C RAM1 Beta subunit of the CAAX farnesyltransferase (FTase) that prenylates the a-factor mating pheromone and Ras proteins; required for the membrane localization of Ras proteins and a-factor; homolog of the mammalian FTase beta subunit Verified chr4:295034-296329 295034-296329 99.2% 113.61 115.16 137.73 116.72 164.96 124.50 114.39 127.22 144.73 0.42 0.52 0.60 0.19 0.63 Matched[867]
YDL089W "Protein of unknown function; interacts with meiotic division protein Csm1p; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery, potential Cdc28p substrate" Uncharacterized chr4:296820-298274 296820-298274 99.0% 119.42 138.17 140.25 143.73 180.52 126.37 128.80 141.99 153.45 0.48 0.58 0.64 0.11 0.42 Matched[868]
YDL088C ASM4 "Nuclear pore complex subunit, part of a subcomplex also containing Nup53p, Nup170p, and Pse1p" Verified chr4:298417-300003 298417-300003 99.1% 170.39 203.45 170.39 162.12 195.18 169.12 186.92 166.26 182.15 0.69 0.67 0.75 0.13 0.68
YDL087C LUC7 Essential protein associated with the U1 snRNP complex; splicing factor involved in recognition of 5' splice site; contains two zinc finger motifs; N-terminal zinc finger binds pre-mRNA Verified chr4:300214-300999 300214-300999 99.0% 52.70 71.98 66.84 65.55 62.98 82.26 62.34 66.20 72.62 0.23 0.27 0.30 0.13 0.79 Covered[869]
YDL086W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YDL086W is not an essential gene" Uncharacterized chr4:301413-302234 301413-302234 98.6% 671.50 913.44 585.09 622.13 790.00 690.02 792.47 603.61 740.01 2.93 2.45 3.07 0.29 0.43 Matched[870]
YDL086C-A "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps uncharacterized ORF YDL086W; identified by gene-trapping, microarray expression analysis, and genome-wide homology searching" Dubious chr4:301655-302089 301655-302089 98.3% 767.25 1003.51 624.56 697.08 823.39 797.66 885.38 660.82 810.53 3.27 2.68 3.36 0.29 NaN Matched[870]
YDL085C-A Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus Uncharacterized chr4:302464-302670 302464-302670 99.6% 553.06 625.83 494.85 509.40 635.54 480.29 589.45 502.12 557.91 2.18 2.04 2.31 0.15 -0.27 Matched[871]
YDL085W NDE2 "Mitochondrial external NADH dehydrogenase, catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p are involved in providing the cytosolic NADH to the mitochondrial respiratory chain" Verified chr4:303211-304848 303211-304848 98.6% 11.14 22.29 13.00 11.76 138.06 102.15 16.72 12.38 120.10 0.06 0.05 0.50 3.28 3.33 Matched[872]
YDL084W SUB2 Component of the TREX complex required for nuclear mRNA export; member of the DEAD-box RNA helicase superfamily and is involved in early and late steps of spliceosome assembly; homolog of the human splicing factor hUAP56 Verified chr4:305237-306577 305237-306577 98.8% 2385.89 1910.52 2149.72 2087.84 1288.77 1067.69 2148.21 2118.78 1178.23 7.93 8.60 4.88 -0.85 -0.74 Matched[873]
YDL083C RPS16B Protein component of the small (40S) ribosomal subunit; identical to Rps16Ap and has similarity to E. coli S9 and rat S16 ribosomal proteins Verified chr4:306926-307789 306926-307333,307766-307789 78.3% 7051.00 5824.09 6415.37 5487.07 946.05 629.71 6437.55 5951.22 787.88 23.76 24.16 3.26 -2.92 -4.12 Matched[875]
YDL082W RPL13A "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl13Bp; not essential for viability; has similarity to rat L13 ribosomal protein" Verified chr4:308424-309388 308424-308427,308793-309388 65.3% 4665.74 3754.55 3655.00 3134.32 594.70 201.64 4210.15 3394.66 398.17 15.54 13.78 1.65 -3.09 -3.58 Matched[876]
YDL081C RPP1A "Ribosomal stalk protein P1 alpha, involved in the interaction between translational elongation factors and the ribosome; accumulation of P1 in the cytoplasm is regulated by phosphorylation and interaction with the P2 stalk component" Verified chr4:309802-310122 309802-310122 96.8% 12476.27 10294.45 11462.59 9769.91 5216.41 4456.96 11385.36 10616.25 4836.69 42.03 43.09 20.04 -1.13 -2.10 Matched[877]
YDL080C THI3 "Probable alpha-ketoisocaproate decarboxylase, may have a role in catabolism of amino acids to long-chain and complex alcohols; required for expression of enzymes involved in thiamine biosynthesis" Verified chr4:310642-312471 310642-312471 99.0% 152.88 168.89 112.59 92.72 70.65 52.43 160.88 102.66 61.54 0.59 0.42 0.25 -0.74 -0.46 Covered/w/another[878]
YDL079C MRK1 Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation Verified chr4:312951-314748 312951-314044,314337-314748 99.2% 66.26 92.36 86.34 97.72 208.15 129.17 79.31 92.03 168.66 0.29 0.37 0.70 0.87 0.99 Covered/w/another[878]
YDL078C MDH3 "Cytoplasmic malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the glyoxylate cycle" Verified chr4:315357-316388 315357-316388 99.0% 751.62 731.07 724.22 715.41 794.68 596.01 741.34 719.81 695.35 2.74 2.92 2.88 -0.05 -0.13 Frag>80[879,880]
YDL077C VAM6 Vacuolar protein that plays a critical role in the tethering steps of vacuolar membrane fusion by facilitating guanine nucleotide exchange on small guanosine triphosphatase Ypt7p Verified chr4:316971-320120 316971-320120 99.2% 73.89 74.21 63.98 66.22 80.61 73.89 74.05 65.10 77.25 0.27 0.26 0.32 0.25 0.90 Matched[881]
YDL076C RXT3 Subunit of the RPD3L complex; involved in histone deacetylation Verified chr4:320668-321552 320668-321552 99.1% 223.54 239.51 280.57 247.49 304.52 221.26 231.53 264.03 262.89 0.85 1.07 1.09 -0.01 0.27 Matched[882]
YDL075W RPL31A "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Bp and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p" Verified chr4:322226-322988 322226-322282,322704-322988 80.0% 10014.62 8051.19 8731.26 7524.68 2650.82 2354.66 9032.91 8127.97 2502.74 33.34 32.99 10.37 -1.70 -3.05 Matched[883]
YDL074C BRE1 "E3 ubiquitin ligase for Rad6p, required for the ubiquitination of histone H2B, recruitment of Rad6p to promoter chromatin and subsequent methylation of histone H3 (on K4 and K79), contains RING finger domain" Verified chr4:324047-326149 324047-326149 99.4% 285.02 253.94 212.33 178.38 151.12 87.51 269.48 195.35 119.32 0.99 0.79 0.49 -0.71 -0.53 Frag>80[885,886]
YDL073W Putative protein of unknown function; YDL073W is not an essential gene Uncharacterized chr4:326613-329567 326613-329567 98.9% 115.29 104.68 84.84 94.08 47.89 42.08 109.99 89.46 44.99 0.41 0.36 0.19 -0.99 -0.45 Matched[887]
YDL072C YET3 Protein of unknown function; YET3 null mutant decreases the level of secreted invertase; homolog of human BAP31 protein Verified chr4:329836-330447 329836-330447 98.7% 787.81 902.01 786.15 910.28 2044.00 1431.63 844.91 848.22 1737.81 3.12 3.44 7.20 1.03 0.70 Frag>80[888,889]
YDL070W BDF2 Protein involved in transcription initiation at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf1p Verified chr4:331025-332941 331025-332941 98.7% 904.91 796.62 724.78 566.83 803.49 560.49 850.77 645.80 681.99 3.14 2.62 2.83 0.08 -0.22 Matched[890]
YDL071C Hypothetical protein Dubious chr4:330667-331041 330667-331041 98.0% 65.28 68.00 51.68 43.52 27.20 48.96 66.64 47.60 38.08 0.25 0.19 0.16 -0.32 1.36 Covered/w/another[890]
YDL068W "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr4:333500-333829 333500-333829 99.5% 73.09 82.22 82.22 70.04 94.40 51.77 77.66 76.13 73.09 0.29 0.31 0.30 -0.06 -0.11 Matched[891]
YDL069C CBS1 "Mitochondrial translational activator of the COB mRNA; membrane protein that interacts with translating ribosomes, acts on the COB mRNA 5'-untranslated leader" Verified chr4:333121-333810 333121-333810 99.4% 93.28 112.22 94.73 87.45 122.43 77.25 102.75 91.09 99.84 0.38 0.37 0.41 0.13 -0.10 Frag<80[891,892]
YDL067C COX9 "Subunit VIIa of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain" Verified chr4:334217-334396 334217-334396 98.6% 940.62 1064.54 1103.97 1160.29 1565.83 895.56 1002.58 1132.13 1230.70 3.70 4.60 5.10 0.12 -0.58 Matched[892]
YDL066W IDP1 "Mitochondrial NADP-specific isocitrate dehydrogenase, catalyzes the oxidation of isocitrate to alpha-ketoglutarate; not required for mitochondrial respiration and may function to divert alpha-ketoglutarate to biosynthetic processes" Verified chr4:334835-336121 334835-336121 98.7% 809.00 1375.61 838.90 1002.59 613.83 784.60 1092.30 920.75 699.22 4.03 3.74 2.90 -0.40 0.12 Matched[893]
YDL065C PEX19 "Chaperone and import receptor for newly-synthesized class I peroxisomal membrane proteins (PMPs), binds PMPs in the cytoplasm and delivers them to the peroxisome for subsequent insertion into the peroxisomal membrane" Verified chr4:336249-337277 336249-337277 99.6% 341.34 298.43 294.53 285.75 364.74 250.64 319.88 290.14 307.69 1.18 1.18 1.27 0.08 0.08 Matched[894]
YDL064W UBC9 SUMO-conjugating enzyme involved in the Smt3p conjugation pathway; nuclear protein required for S- and M-phase cyclin degradation and mitotic control; involved in proteolysis mediated by the anaphase-promoting complex cyclosome (APCC) Verified chr4:337487-338070 337487-337524,337635-338070 98.6% 483.47 440.68 468.49 367.95 316.61 243.87 462.07 418.22 280.24 1.71 1.70 1.16 -0.58 -0.59 Matched[895]
YDL062W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps uncharacterized ORF YDL063C; YDL062W is not essential" Dubious chr4:339857-340282 339857-340282 98.9% 54.59 33.23 37.97 23.73 2.37 2.37 43.91 30.85 2.37 0.16 0.13 0.01 -3.70 -0.50 Covered/w/another[896]
YDL063C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YDL063C is not an essential gene Uncharacterized chr4:338272-340134 338272-340134 99.2% 121.74 62.22 72.50 46.53 8.66 2.71 91.98 59.52 5.68 0.34 0.24 0.02 -3.39 -3.06 Matched[896]
YDL061C RPS29B Protein component of the small (40S) ribosomal subunit; nearly identical to Rps29Ap and has similarity to rat S29 and E. coli S14 ribosomal proteins Verified chr4:340628-341220 340628-340810,341219-341220 80.4% 8380.85 6707.37 7426.49 6075.61 1384.49 551.11 7544.10 6751.05 967.80 27.85 27.40 4.01 -2.80 -4.24 Matched[897]
YDL060W TSR1 "Protein required for processing of 20S pre-rRNA in the cytoplasm, associates with pre-40S ribosomal particles" Verified chr4:341619-343985 341619-343985 98.6% 212.15 126.43 135.43 99.00 10.29 12.00 169.29 117.22 11.14 0.62 0.48 0.05 -3.39 -2.21 Matched[898]
YDL059C RAD59 Protein involved in the repair of double-strand breaks in DNA during vegetative growth via recombination and single-strand annealing; anneals complementary single-stranded DNA; homologous to Rad52p Verified chr4:344237-344953 344237-344953 99.2% 82.92 116.65 81.52 77.30 163.04 101.19 99.79 79.41 132.12 0.37 0.32 0.55 0.73 0.54 Matched[899]
YDL058W USO1 "Essential protein involved in intracellular protein transport, coiled-coil protein necessary for transport from ER to Golgi; required for assembly of the ER-to-Golgi SNARE complex" Verified chr4:345665-351037 345665-351037 98.5% 159.61 156.78 121.45 120.32 64.22 86.13 158.19 120.89 75.18 0.58 0.49 0.31 -0.69 -0.23 Matched[900]
YDL057W Putative protein of unknown function; YDL057W is not an essential gene Uncharacterized chr4:351434-352420 351434-352420 98.8% 38.97 64.60 46.15 26.66 130.23 106.65 51.79 36.40 118.44 0.19 0.15 0.49 1.70 1.58 Covered/w/another[901]
YDL056W MBP1 "Transcription factor involved in regulation of cell cycle progression from G1 to S phase, forms a complex with Swi6p that binds to MluI cell cycle box regulatory element in promoters of DNA synthesis genes" Verified chr4:352877-355378 352877-355378 98.8% 97.50 121.77 99.92 91.43 118.94 118.13 109.63 95.67 118.53 0.40 0.39 0.49 0.31 0.64 Covered/w/another[901]
YDL055C PSA1 "GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure" Verified chr4:355674-356759 355674-356759 98.9% 8745.64 7299.98 7522.46 6574.82 2156.85 1731.44 8022.81 7048.64 1944.15 29.62 28.61 8.06 -1.86 -2.19 Frag>80[902,903,904]
YDL054C MCH1 "Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport" Verified chr4:359825-361285 359825-361285 98.6% 120.15 149.32 119.46 102.10 125.01 85.43 134.74 110.78 105.22 0.50 0.45 0.44 -0.07 0.25 Matched[905]
YDL053C PBP4 "Pbp1p binding protein, interacts strongly with Pab1p-binding protein 1 (Pbp1p) in the yeast two-hybrid system; also interacts with Lsm12p in a copurification assay" Verified chr4:361699-362256 361699-362256 98.8% 562.23 516.89 540.47 473.36 623.89 359.10 539.56 506.91 491.50 1.99 2.06 2.04 -0.04 -0.26 Matched[906]
YDL052C SLC1 "1-acyl-sn-gylcerol-3-phosphate acyltransferase, catalyzes the acylation of lysophosphatidic acid to form phosphatidic acid, a key intermediate in lipid metabolism; located in lipid particles and endoplasmic reticulum" Verified chr4:362672-363583 362672-363583 98.9% 437.92 596.45 465.63 334.81 460.09 443.46 517.18 400.22 451.77 1.91 1.62 1.87 0.17 0.52 Matched[907]
YDL051W LHP1 RNA binding protein required for maturation of tRNA and snRNA precursors; acts as a molecular chaperone for RNAs transcribed by polymerase III; homologous to human La (SS-B) autoantigen Verified chr4:363952-364779 363952-364779 98.5% 622.87 277.10 421.78 378.87 105.45 89.51 449.98 400.33 97.48 1.66 1.63 0.40 -2.04 -1.97 Matched[908]
YDL050C "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr4:364446-364817 364446-364817 98.6% 725.12 288.96 460.70 384.37 117.22 106.32 507.04 422.54 111.77 1.87 1.72 0.46 -1.92 -1.13 Matched[908]
YDL049C KNH1 "Protein with similarity to Kre9p, which is involved in cell wall beta 1,6-glucan synthesis; overproduction suppresses growth defects of a kre9 null mutant" Verified chr4:365068-365874 365068-365874 99.1% 56.29 40.03 56.29 28.77 12.51 28.77 48.16 42.53 20.64 0.18 0.17 0.09 -1.04 -1.16 Covered/w/another[909]
YDL048C STP4 "Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p" Verified chr4:366739-368211 366739-368211 98.4% 105.58 74.53 70.39 56.59 52.45 53.14 90.06 63.49 52.79 0.33 0.26 0.22 -0.27 0.25 Covered/w/another[909]
YDL047W SIT4 Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization Verified chr4:369769-370704 369769-370704 98.5% 356.95 337.42 372.14 289.68 334.16 237.60 347.18 330.91 285.88 1.28 1.34 1.18 -0.21 0.09 Matched[910]
YDL046W NPC2 "Functional homolog of human NPC2/He1, which is a cholesterol-binding protein whose deficiency causes Niemann-Pick type C2 disease involving retention of cholesterol in lysosomes" Verified chr4:371237-371758 371237-371758 98.9% 997.66 1040.28 1214.63 1038.34 1768.67 1534.26 1018.97 1126.48 1651.46 3.76 4.57 6.84 0.55 0.98 Matched[911]
YDL045W-A MRP10 Mitochondrial ribosomal protein of the small subunit Verified chr4:372245-372532 372245-372532 98.5% 525.03 535.60 539.13 570.84 680.08 387.61 530.32 554.98 533.84 1.96 2.25 2.21 -0.06 0.02 Matched[912]
YDL045C FAD1 "Flavin adenine dinucleotide (FAD) synthetase, performs the second step in synthesis of FAD from riboflavin" Verified chr4:372685-373605 372685-373605 99.1% 158.82 153.34 150.05 134.72 197.15 131.43 156.08 142.39 164.29 0.58 0.58 0.68 0.21 0.13 Matched[913]
YDL044C MTF2 Mitochondrial matrix protein that interacts with an N-terminal region of mitochondrial RNA polymerase (Rpo41p) and couples RNA processing and translation to transcription Verified chr4:373964-375286 373964-375286 99.4% 63.87 73.76 63.87 71.48 82.12 52.47 68.82 67.68 67.30 0.25 0.27 0.28 -0.01 0.22 Covered/w/another[914]
YDL043C PRP11 "Subunit of the SF3a splicing factor complex, required for spliceosome assembly" Verified chr4:375677-376477 375677-376477 99.3% 142.00 128.18 118.13 85.45 54.04 75.40 135.09 101.79 64.72 0.50 0.41 0.27 -0.65 -0.24 Covered/w/another[914]
YDL041W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene SIR2/YDL042C" Dubious chr4:378099-378452 378099-378452 99.0% 68.51 39.96 77.07 71.36 17.13 28.54 54.23 74.22 22.84 0.20 0.30 0.09 -1.70 -0.43 Covered/w/another[914]
YDL042C SIR2 "Conserved NAD+ dependent histone deacetylase of the Sirtuin family involved in regulation of lifespan; plays roles in silencing at HML, HMR, telomeres, and the rDNA locus; negatively regulates initiation of DNA replication" Verified chr4:376754-378442 376754-378442 99.0% 99.27 82.53 102.86 80.14 39.47 38.87 90.90 91.50 39.17 0.34 0.37 0.16 -1.22 -0.47 Covered/w/another[914]
YDL040C NAT1 "Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing" Verified chr4:378871-381435 378871-381435 99.1% 493.34 383.18 437.47 432.75 214.80 218.34 438.26 435.11 216.57 1.62 1.77 0.90 -1.01 -0.49 Matched[915]
YDL039C PRM7 "Pheromone-regulated protein, predicted to have one transmembrane segment; promoter contains Gcn4p binding elements" Verified chr4:381983-382330 381983-382330 98.6% 26.23 14.57 17.49 14.57 5.83 17.49 20.40 16.03 11.66 0.08 0.07 0.05 -0.46 0.00
YDL038C Putative protein of unknown function; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) Uncharacterized chr4:382327-384078 382327-384078 83.3% 30.16 8.23 7.54 8.91 2.74 5.48 19.20 8.23 4.11 0.07 0.03 0.02 -1.00 0.23
YDL037C BSC1 "Protein of unconfirmed function, similar to cell surface flocculin Muc1p; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression" Verified chr4:384598-385584 384598-385584 76.1% 21.31 7.99 14.65 7.99 2.66 6.66 14.65 11.32 4.66 0.05 0.05 0.02 -1.28 -0.17 Frag<80[917]
YDL036C PUS9 Mitochondrial tRNA pseudouridine synthase involved in pseudouridylation of mitochondrial tRNAs at position 32 Verified chr4:387510-388898 387510-388898 99.3% 87.03 81.95 53.67 67.45 41.34 33.36 84.49 60.56 37.35 0.31 0.25 0.15 -0.70 -0.30 Matched[918]
YDL034W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps with verified gene GPR1/YDL035C; YDL034W is not an essential gene" Dubious chr4:391780-392124 391780-392124 98.6% 58.81 55.87 47.05 70.57 61.75 97.04 57.34 58.81 79.39 0.21 0.24 0.33 0.43 0.61 Covered[920]
YDL035C GPR1 "Plasma membrane G protein coupled receptor (GPCR) that interacts with the heterotrimeric G protein alpha subunit, Gpa2p, and with Plc1p; sensor that integrates nutritional signals with the modulation of cell fate via PKA and cAMP synthesis" Verified chr4:389169-392054 389169-392054 96.7% 155.11 159.77 150.09 147.23 202.04 193.80 157.44 148.66 197.92 0.58 0.60 0.82 0.41 1.10 Frag<80[919]
YDL032W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene SLM3/YDL033C; YDL032W is not an essential gene" Dubious chr4:393687-393998 393687-393998 99.2% 35.53 35.53 19.38 12.92 16.15 16.15 35.53 16.15 16.15 0.13 0.07 0.07 0.00 1.87
YDL033C SLM3 "tRNA-specific 2-thiouridylase, responsible for 2-thiolation of the wobble base of mitochondrial tRNAs; human ortholog is implicated in myoclonus epilepsy associated with ragged red fibers (MERRF)" Verified chr4:392656-393909 392656-393909 98.8% 50.84 71.82 40.35 37.12 41.96 25.01 61.33 38.73 33.49 0.23 0.16 0.14 -0.21 0.18 Overlap[920]
YDL031W DBP10 "Putative ATP-dependent RNA helicase of the DEAD-box protein family, constituent of 66S pre-ribosomal particles; essential protein involved in ribosome biogenesis" Verified chr4:394214-397201 394214-397201 98.5% 268.09 135.24 166.84 139.31 24.80 17.67 201.66 153.08 21.24 0.74 0.62 0.09 -2.85 -2.83 Matched[921]
YDL030W PRP9 "Subunit of the SF3a splicing factor complex, required for spliceosome assembly; acts after the formation of the U1 snRNP-pre-mRNA complex" Verified chr4:397534-399126 397534-399126 98.5% 78.99 71.98 51.60 56.06 63.07 31.21 75.49 53.83 47.14 0.28 0.22 0.20 -0.19 0.01 Matched[922]
YDL029W ARP2 "Essential component of the Arp2/3 complex, which is a highly conserved actin nucleation center required for the motility and integrity of actin patches; involved in endocytosis and membrane growth and polarity" Verified chr4:399337-400635 399337-399358,399482-400635 98.7% 883.82 972.54 963.07 951.01 1059.55 987.19 928.18 957.04 1023.37 3.43 3.88 4.24 0.10 0.42 Frag>80[923,924]
YDL028C MPS1 "Dual-specificity kinase required for spindle pole body (SPB) duplication and spindle checkpoint function; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, and checkpoint protein Mad1p" Verified chr4:400994-403288 400994-403288 99.2% 92.20 93.96 69.81 76.84 89.13 90.89 93.08 73.32 90.01 0.34 0.30 0.37 0.30 0.72 Matched[925]
YDL026W "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr4:404746-405057 404746-405057 99.0% 87.43 158.66 132.76 174.85 362.66 200.76 123.04 153.80 281.71 0.45 0.62 1.17 0.87 1.15 Covered/w/another[926]
YDL027C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YDL027C is not an essential gene" Uncharacterized chr4:403692-404954 403692-404954 99.0% 186.25 250.20 227.82 270.98 512.39 280.58 218.23 249.40 396.48 0.81 1.01 1.64 0.67 0.58 Covered/w/another[926]
YDL025W-A "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the ORF YDL025C; identified by gene-trapping, microarray expression analysis, and genome-wide homology searching" Dubious chr4:405407-405511 405407-405511 98.7% 299.16 386.01 202.65 241.25 752.71 405.31 342.58 221.95 579.01 1.26 0.90 2.40 1.38 NaN Covered/w/another[926]
YDL025C "Putative protein kinase, potentially phosphorylated by Cdc28p; YDL025C is not an essential gene" Uncharacterized chr4:405341-407203 405341-407203 98.9% 200.81 249.66 222.52 209.50 387.52 353.87 225.24 216.01 370.69 0.83 0.88 1.54 0.78 0.75 Covered/w/another[926]
YDL024C DIA3 "Protein of unknown function, involved in invasive and pseudohyphal growth" Verified chr4:408448-409854 408448-409854 99.0% 8.61 12.20 10.05 6.46 68.90 51.67 10.41 8.25 60.29 0.04 0.03 0.25 2.87 2.82 Covered/w/another[927]
YDL022C-A Dubious open reading frame unlikely to encode a protein; partially overlaps the verified gene DIA3; identified by fungal homology and RT-PCR Dubious chr4:409805-410053 409805-410053 98.5% 0.00 16.30 4.08 4.08 24.45 20.38 8.15 4.08 22.41 0.03 0.02 0.09 2.46 NaN Covered/w/another[927]
YDL022W GPD1 "NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p" Verified chr4:411822-412997 411822-412997 98.6% 585.51 889.91 1177.92 1121.87 3043.12 2787.01 737.71 1149.90 2915.06 2.72 4.67 12.08 1.34 1.17 Matched[929]
YDL023C "Dubious open reading frame, unlikely to encode a protein; not conserved in other Saccharomyces species; overlaps the verified gene GPD1; deletion confers sensitivity to GSAO; deletion in cyr1 mutant results in loss of stress resistance" Dubious chr4:411758-412078 411758-412078 98.7% 340.87 511.31 640.72 624.93 1552.87 1562.34 426.09 632.82 1557.60 1.57 2.57 6.45 1.30 -0.00 Covered/w/another[929]
YDL021W GPM2 Homolog of Gpm1p phosphoglycerate mutase which converts 3-phosphoglycerate to 2-phosphoglycerate in glycolysis; may be non-functional derivative of a gene duplication event Verified chr4:413950-414885 413950-414885 98.7% 96.33 324.70 127.72 134.21 996.84 521.69 210.52 130.96 759.27 0.78 0.53 3.15 2.54 2.33 Covered[930]
YDL020C RPN4 Transcription factor that stimulates expression of proteasome genes; Rpn4p levels are in turn regulated by the 26S proteasome in a negative feedback control mechanism; RPN4 is transcriptionally regulated by various stress responses Verified chr4:415110-416705 415110-416705 99.2% 139.65 191.46 171.24 130.80 1176.56 730.45 165.55 151.02 953.50 0.61 0.61 3.95 2.66 2.62 Matched[931]
YDL019C OSH2 "Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability" Verified chr4:417660-421511 417660-421511 99.2% 166.23 161.26 184.82 175.66 285.87 379.33 163.75 180.24 332.60 0.60 0.73 1.38 0.88 1.26 Matched[933]
YDL018C ERP3 "Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport" Verified chr4:422830-423507 422830-423507 99.2% 156.11 197.75 193.28 156.11 521.87 202.21 176.93 174.70 362.04 0.65 0.71 1.50 1.05 0.53 Frag>80[934,935]
YDL017W CDC7 DDK (Dbf4-dependent kinase) catalytic subunit required for firing origins and replication fork progression in mitosis through phosphorylation of Mcm2-7p complexes and Cdc45p; kinase activity correlates with cyclical DBF4 expression Verified chr4:424206-425729 424206-425729 98.8% 43.19 54.49 39.20 44.52 53.82 43.19 48.84 41.86 48.51 0.18 0.17 0.20 0.21 0.61 Matched[936]
YDL016C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF CDC7/YDL153C, the catalytic subunit of a complex that regulates DNA replication" Dubious chr4:425567-425869 425567-425869 98.9% 263.59 286.95 236.90 293.62 380.37 190.18 275.27 265.26 285.28 1.02 1.08 1.18 0.10 -0.50 Frag<80[937]
YDL015C TSC13 "Enoyl reductase that catalyzes the last step in each cycle of very long chain fatty acid elongation, localizes to the ER, highly enriched in a structure marking nuclear-vacuolar junctions, coimmunoprecipitates with elongases Fen1p and Sur4p" Verified chr4:425999-426931 425999-426931 99.0% 931.49 890.33 902.25 909.83 916.33 724.61 910.91 906.04 820.47 3.36 3.68 3.40 -0.14 0.05 Frag>80[937,938]
YDL014W NOP1 "Nucleolar protein, component of the small subunit processome complex, which is required for processing of pre-18S rRNA; has similarity to mammalian fibrillarin" Verified chr4:427361-428344 427361-428344 89.3% 2063.94 1321.70 1728.11 1399.11 162.79 43.26 1692.82 1563.61 103.03 6.25 6.35 0.43 -3.92 -3.58 Matched[939]
YDL013W SLX5 Subunit of the Slx5-Slx8 substrate-specific ubiquitin ligase complex; stimulated by prior attachment of SUMO to the substrate Verified chr4:429064-430923 429064-430923 98.4% 100.03 90.19 77.08 66.69 98.39 81.45 95.11 71.88 89.92 0.35 0.29 0.37 0.32 0.24 Matched[940]
YDL012C Plasma membrane protein of unknown function; YDL012C is not an essential gene Uncharacterized chr4:431105-431514 431105-431383,431470-431514 98.5% 394.98 373.04 470.22 388.71 282.13 200.63 384.01 429.47 241.38 1.42 1.74 1.00 -0.83 -0.37 Matched[941]
YDL010W Putative thiol oxidoreductase; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; non-essential gene Uncharacterized chr4:432327-433022 432327-433022 98.6% 303.24 294.50 253.68 225.97 345.52 193.90 298.87 239.83 269.71 1.10 0.97 1.12 0.17 0.46 Matched[943]
YDL011C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the uncharacterized ORF YDL010W" Dubious chr4:432305-432628 432305-432628 98.5% 241.16 181.65 169.12 172.26 209.84 134.67 211.41 170.69 172.26 0.78 0.69 0.71 0.01 0.03 Matched[943]
YDL009C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YDL010W; YDL009C is not an essential gene" Dubious chr4:432922-433245 432922-433245 98.5% 394.83 347.83 347.83 228.75 438.70 235.02 371.33 288.29 336.86 1.37 1.17 1.40 0.22 -0.02 Matched[943]
YDL008W APC11 "Catalytic core subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" Verified chr4:433494-433991 433494-433991 98.7% 207.62 177.08 183.19 185.23 225.94 124.16 192.35 184.21 175.05 0.71 0.75 0.73 -0.07 -0.49 Matched[944]
YDL007C-A Putative protein of unknown function Uncharacterized chr4:436564-436821 436564-436821 98.6% 0.00 0.00 0.00 0.00 0.00 15.73 0.00 0.00 7.86 0.00 0.00 0.03 Inf NaN
YDL007W RPT2 One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for normal peptide hydrolysis by the core 20S particle Verified chr4:438044-439357 438044-439357 98.5% 850.28 662.61 746.79 774.59 1210.93 868.04 756.44 760.69 1039.48 2.79 3.09 4.31 0.45 0.36 Matched[945]
YDL006W PTC1 "Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by dephosphorylating Hog1p; mutation delays mitochondrial inheritance; deletion reveals defects in precursor tRNA splicing, sporulation and cell separation" Verified chr4:439906-440751 439906-440751 98.5% 159.58 166.77 148.78 140.38 183.57 100.78 163.18 144.58 142.18 0.60 0.59 0.59 -0.02 0.13 Matched[946]
YDL005C MED2 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation Verified chr4:441011-442306 441011-442306 99.0% 275.06 261.03 260.25 253.24 288.30 238.43 268.04 256.74 263.37 0.99 1.04 1.09 0.04 0.37 Matched[947]
YDL004W ATP16 "Delta subunit of the central stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated" Verified chr4:443026-443508 443026-443508 99.0% 721.38 905.38 928.38 1078.93 1662.31 1166.75 813.38 1003.66 1414.53 3.00 4.07 5.86 0.50 0.33 Matched[948]
YDL003W MCD1 Essential protein required for sister chromatid cohesion in mitosis and meiosis; subunit of the cohesin complex; expression is cell cycle regulated and peaks in S phase Verified chr4:444680-446380 444680-446380 98.6% 238.46 197.92 218.19 182.42 93.60 49.48 218.19 200.31 71.54 0.81 0.81 0.30 -1.49 -0.84 Matched[949]
YDL002C NHP10 "Protein related to mammalian high mobility group proteins; likely component of the INO80 complex, which is an ATP-dependent chromatin-remodeling complex" Verified chr4:446964-447575 446964-447575 99.5% 197.04 205.25 201.97 188.83 325.12 169.13 201.15 195.40 247.13 0.74 0.79 1.02 0.34 -0.21 Frag>80[950,951]
YDL001W RMD1 Cytoplasmic protein required for sporulation Verified chr4:447981-449273 447981-449273 98.7% 98.71 86.18 90.88 71.29 68.94 52.49 92.45 81.09 60.72 0.34 0.33 0.25 -0.42 -0.11 Matched[952]
YDR001C NTH1 "Neutral trehalase, degrades trehalose; required for thermotolerance and may mediate resistance to other cellular stresses; may be phosphorylated by Cdc28p" Verified chr4:450217-452472 450217-452472 98.7% 270.78 466.56 363.28 428.84 1874.34 1936.31 368.67 396.06 1905.32 1.36 1.61 7.89 2.27 2.55 Frag>80[953,954]
YDR002W YRB1 "Ran GTPase binding protein; involved in nuclear protein import and RNA export, ubiquitin-mediated protein degradation during the cell cycle; shuttles between the nucleus and cytoplasm; is essential; homolog of human RanBP1" Verified chr4:453042-453647 453042-453647 98.3% 2668.72 2337.86 2342.90 2235.41 3308.61 2485.65 2503.29 2289.15 2897.13 9.24 9.29 12.00 0.34 0.06 Matched[955]
YDR003W RCR2 "Vacuolar protein that presumably functions within the endosomal-vacuolar trafficking pathway, affecting events that determine whether plasma membrane proteins are degraded or routed to the plasma membrane; similar to Rcr1p" Verified chr4:454119-454751 454119-454751 98.6% 181.14 147.48 181.14 182.74 447.23 264.49 164.31 181.94 355.86 0.61 0.74 1.47 0.97 1.22 Matched[956]
YDR003W-A Putative protein of unknown function; identified by expression profiling and mass spectrometry Uncharacterized chr4:454779-454901 454779-454901 98.4% 247.85 198.28 206.54 256.11 817.90 404.82 223.06 231.33 611.36 0.82 0.94 2.53 1.40 NaN Matched[956]
YDR004W RAD57 Protein that stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; forms heterodimer with Rad55p Verified chr4:455198-456580 455198-456580 98.7% 86.43 111.33 75.44 61.52 125.98 70.31 98.88 68.48 98.14 0.37 0.28 0.41 0.52 0.29 Matched[957]
YDR005C MAF1 Negative regulator of RNA polymerase III; component of several signaling pathways that repress polymerase III transcription in response to changes in cellular environment; targets the initiation factor TFIIIB Verified chr4:456833-458100 456833-458014,458095-458100 99.0% 246.66 244.11 237.30 235.60 341.92 198.18 245.38 236.45 270.05 0.91 0.96 1.12 0.19 0.21 Matched[958]
YDR006C SOK1 Protein whose overexpression suppresses the growth defect of mutants lacking protein kinase A activity; involved in cAMP-mediated signaling; localized to the nucleus; similar to the mouse testis-specific protein PBS13 Verified chr4:458539-461244 458539-461244 98.9% 139.79 130.44 137.92 119.60 134.55 168.57 135.11 128.76 151.56 0.50 0.52 0.63 0.24 0.84 Matched[959]
YDR007W TRP1 "Phosphoribosylanthranilate isomerase that catalyzes the third step in tryptophan biosynthesis; in 2004, the sequence of TRP1 from strain S228C was updated by changing the previously annotated internal STOP (TAA) to serine (TCA)" Verified chr4:461839-462513 461839-462513 98.5% 243.59 287.20 285.70 293.21 592.44 269.16 265.40 289.46 430.80 0.98 1.17 1.78 0.57 0.32 Frag>80[960,961]
YDR008C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr4:462249-462599 462249-462599 98.4% 254.76 243.18 280.82 289.51 555.85 251.87 248.97 285.16 403.86 0.92 1.16 1.67 0.50 0.03 Matched[961]
YDR009W GAL3 Transcriptional regulator involved in activation of the GAL genes in response to galactose; forms a complex with Gal80p to relieve Gal80p inhibition of Gal4p; binds galactose and ATP but does not have galactokinase activity Verified chr4:463431-464993 463431-464993 98.8% 20.07 19.42 23.95 17.48 27.19 23.95 19.75 20.72 25.57 0.07 0.08 0.11 0.30 1.02
YDR010C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr4:465048-465380 465048-465380 98.6% 9.13 27.40 21.31 9.13 21.31 12.18 18.27 15.22 16.75 0.07 0.06 0.07 0.14 0.91
YDR011W SNQ2 "Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter involved in multidrug resistance and resistance to singlet oxygen species" Verified chr4:465916-470421 465916-470421 98.7% 276.22 297.79 272.62 274.65 462.31 651.10 287.01 273.63 556.71 1.06 1.11 2.31 1.02 1.47 Frag>80[963,964]
YDR012W RPL4B "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl4Ap and has similarity to E. coli L4 and rat L4 ribosomal proteins" Verified chr4:471850-472938 471850-472938 7.4% 3749.61 2644.59 2570.10 1514.74 831.87 235.90 3197.10 2042.42 533.89 11.80 8.29 2.21 -1.94 -2.90 Frag<80[966,967,968,969]
YDR013W PSF1 "Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery" Verified chr4:473154-473780 473154-473780 98.8% 122.70 158.22 98.49 119.48 74.27 58.12 140.46 108.98 66.20 0.52 0.44 0.27 -0.72 -0.78 Matched[970]
YDR014W RAD61 Protein of unknown function; mutation confers radiation sensitivity Verified chr4:474043-475986 474043-475986 99.0% 45.22 46.78 41.06 32.23 41.58 36.90 46.00 36.64 39.24 0.17 0.15 0.16 0.10 0.79 Matched[971]
YDR014W-A HED1 "Meiosis-specific protein that down-regulates Rad51p-mediated mitotic recombination when the meiotic recombination machinery is impaired; early meiotic gene, transcribed specifically during meiotic prophase" Verified chr4:477794-478282 477794-478282 98.3% 2.08 4.16 6.24 4.16 24.95 14.56 3.12 5.20 19.76 0.01 0.02 0.08 1.93 NaN Frag<80[973]
YDR015C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene HED1/YDR014W-A" Dubious chr4:477957-478196 477957-478196 98.1% 4.25 8.50 0.00 4.25 25.49 8.50 6.37 2.12 16.99 0.02 0.01 0.07 3.00 0.12 Matched[973]
YDR016C DAD1 "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis" Verified chr4:478471-478755 478471-478755 99.3% 339.12 356.79 423.90 310.86 558.14 335.59 347.95 367.38 446.86 1.28 1.49 1.85 0.28 -0.19 Matched[973]
YDR017C KCS1 "Inositol hexakisphosphate (IP6) kinase, also has inositol heptakisphosphate (IP7) kinase activity, required for proper vacuole morphology and involved in salt stress response; contains two leucine heptad repeats" Verified chr4:479112-482264 479112-482264 99.1% 146.53 164.12 116.46 103.98 81.58 74.54 155.33 110.22 78.06 0.57 0.45 0.32 -0.50 -0.02 Covered/w/another[974]
YDR018C "Probable membrane protein with three predicted transmembrane domains; homologous to Ybr042cp, similar to C. elegans F55A11.5 and maize 1-acyl-glycerol-3-phosphate acyltransferase; null exhibits no apparent phenotype" Uncharacterized chr4:482667-483857 482667-483857 99.0% 11.03 16.96 13.57 23.75 153.50 90.75 13.99 18.66 122.12 0.05 0.08 0.51 2.71 2.60 Covered/w/another[974]
YDR019C GCV1 "T subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of levels of 5,10-methylene-THF in the cytoplasm" Verified chr4:484160-485362 484160-485362 99.2% 1380.38 1268.98 1458.28 1228.77 689.35 479.11 1324.68 1343.52 584.23 4.89 5.45 2.42 -1.20 -1.40 Frag>80[975,976]
YDR020C Predicted protein shares weak similarity with uridine kinases and with phosphoribokinases; null mutant suppresses dst1delta sensitivity for 6-azauracil Uncharacterized chr4:485743-486441 485743-486441 99.4% 110.79 84.89 76.26 69.06 21.58 18.71 97.84 72.66 20.14 0.36 0.29 0.08 -1.85 -2.49 Matched[977]
YDR021W FAL1 "Nucleolar protein required for maturation of 18S rRNA, member of the eIF4A subfamily of DEAD-box ATP-dependent RNA helicases" Verified chr4:486801-488000 486801-488000 98.8% 78.48 36.29 50.63 33.76 7.59 7.59 57.38 42.19 7.59 0.21 0.17 0.03 -2.47 -2.16 Matched[978]
YDR022C CIS1 Protein required for autophagosome formation in concert with Atg17p; may be involved in microtubule organization; high-copy suppressor of CIK1 deletion Verified chr4:488069-488659 488069-488659 99.4% 119.14 108.93 124.25 86.80 275.73 248.49 114.03 105.52 262.11 0.42 0.43 1.09 1.31 1.45 Matched[979]
YDR023W SES1 "Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine substrate, interacts with peroxin Pex21p" Verified chr4:489505-490893 489505-490893 98.7% 1821.42 1488.93 1622.36 1634.76 604.47 462.28 1655.17 1628.56 533.37 6.11 6.61 2.21 -1.61 -1.37 Matched[980]
YDR024W FYV1 "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; mutation decreases survival upon exposure to K1 killer toxin" Dubious chr4:491014-491499 491014-491499 98.9% 164.33 85.28 128.97 108.16 27.04 24.96 124.80 118.56 26.00 0.46 0.48 0.11 -2.19 -0.59 Overlap[980,981]
YDR025W RPS11A Protein component of the small (40S) ribosomal subunit; identical to Rps11Bp and has similarity to E. coli S17 and rat S11 ribosomal proteins Verified chr4:491512-492321 491512-491556,491896-492321 50.9% 6600.83 4869.26 5641.17 4247.57 963.84 509.04 5735.05 4944.37 736.44 21.17 20.07 3.05 -2.75 -3.20 Matched[981]
YDR026C "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; Myb-like DNA-binding protein that may bind to the Ter region of rDNA; interacts physically with Fob1p" Verified chr4:492553-494265 492553-494265 99.5% 146.15 132.65 106.83 79.83 85.11 41.67 139.40 93.33 63.39 0.51 0.38 0.26 -0.56 -0.79 Matched[982]
YDR027C VPS54 "Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; potentially phosphorylated by Cdc28p" Verified chr4:494646-497315 494646-497315 99.4% 112.34 128.17 119.12 105.93 183.21 144.00 120.25 112.53 163.61 0.44 0.46 0.68 0.54 0.60 Matched[983]
YDR028C REG1 "Regulatory subunit of type 1 protein phosphatase Glc7p, involved in negative regulation of glucose-repressible genes" Verified chr4:497832-500876 497832-500876 99.2% 359.54 343.98 314.84 343.65 372.45 420.45 351.76 329.25 396.45 1.30 1.34 1.64 0.27 0.94 Frag>80[984,985]
YDR029W "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr4:501097-501411 501097-501411 99.4% 143.75 111.81 121.39 127.78 198.06 169.31 127.78 124.58 183.68 0.47 0.51 0.76 0.56 0.05 Covered/w/another[985]
YDR030C RAD28 Protein involved in transcription-coupled repair nucleotide excision repair of UV-induced DNA lesions; homolog of human CSA protein Verified chr4:501750-503270 501750-503270 99.4% 36.39 43.67 35.07 15.88 77.42 44.34 40.03 25.48 60.88 0.15 0.10 0.25 1.26 1.10 Matched[986]
YDR031W MIC14 Mitochondrial intermembrane space cysteine motif protein of 14 kDa Verified chr4:503495-503860 503495-503860 98.5% 177.57 241.39 255.26 283.01 879.54 463.35 209.48 269.13 671.45 0.77 1.09 2.78 1.32 0.60 Matched[987]
YDR032C PST2 "Protein with similarity to members of a family of flavodoxin-like proteins; induced by oxidative stress in a Yap1p dependent manner; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr4:504096-504692 504096-504692 98.7% 1699.13 2210.06 2009.76 1929.98 4223.21 3108.00 1954.59 1969.87 3665.61 7.22 8.00 15.19 0.90 0.64 Matched[988]
YDR033W MRH1 "Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the authentic, non-tagged protein is detected in mitochondria in a phosphorylated state; has similarity to Hsp30p and Yro2p" Verified chr4:508144-509106 508144-509106 97.3% 5250.07 7606.08 4782.49 5044.04 2860.96 2176.67 6428.08 4913.26 2518.82 23.73 19.94 10.44 -0.96 -1.48 Matched[990]
YDR034C LYS14 Transcriptional activator involved in regulation of genes of the lysine biosynthesis pathway; requires 2-aminoadipate semialdehyde as co-inducer Verified chr4:509734-512106 509734-512106 99.1% 127.52 160.67 95.21 81.19 96.06 92.66 144.10 88.20 94.36 0.53 0.36 0.39 0.10 0.24 Covered[991]
YDR034C-A Putative protein of unknown function; contained within the solo Ty1 LTR element YDRWdelta7 Uncharacterized chr4:520513-520689 520513-520689 29.0% 38.96 0.00 0.00 0.00 19.48 0.00 19.48 0.00 9.74 0.07 0.00 0.04 Inf 0.03
YDR034W-B Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery Uncharacterized chr4:521311-521466 521311-521466 99.2% 6.46 12.92 12.92 0.00 2138.93 1105.01 9.69 6.46 1621.97 0.04 0.03 6.72 7.97 3.76 Matched[993]
YDR035W ARO3 "3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by phenylalanine or high concentration of tyrosine or tryptophan" Verified chr4:521813-522925 521813-522925 98.5% 867.17 1742.55 790.58 866.26 411.25 329.18 1304.86 828.42 370.21 4.82 3.36 1.53 -1.16 -0.95 Matched[994]
YDR036C EHD3 "Protein with an indirect role in endocytic membrane trafficking, member of a family of enoyl-CoA hydratase/isomerases; non-tagged protein is detected in highly purified mitochondria in high-throughput studies; phosphorylated" Verified chr4:523208-524710 523208-524710 98.9% 197.75 159.41 189.01 166.14 168.83 164.79 178.58 177.57 166.81 0.66 0.72 0.69 -0.09 0.23 Matched[995]
YDR037W KRS1 Lysyl-tRNA synthetase; also identified as a negative regulator of general control of amino acid biosynthesis Verified chr4:525437-527212 525437-527212 98.5% 1968.00 1815.43 1726.29 1669.71 368.57 312.00 1891.71 1698.00 340.29 6.98 6.89 1.41 -2.32 -1.59 Matched[996]
YDR038C ENA5 "Protein with similarity to P-type ATPase sodium pumps, member of the Na+ efflux ATPase family" Verified chr4:527419-530694 527419-530694 3.7% 122.66 196.25 179.90 106.30 122.66 40.89 159.45 143.10 81.77 0.59 0.58 0.34 -0.81 -0.24 Overlap[996]
YDR039C ENA2 "P-type ATPase sodium pump, involved in Na+ efflux to allow salt tolerance; likely not involved in Li+ efflux" Verified chr4:531304-534579 531304-534579 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.80
YDR040C ENA1 "P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance" Verified chr4:535189-538464 535189-538464 8.9% 13.72 27.44 3.43 20.58 48.02 68.60 20.58 12.01 58.31 0.08 0.05 0.24 2.28 0.65 Frag<80[997]
YDR041W RSM10 "Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S10 ribosomal protein; essential for viability, unlike most other mitoribosomal proteins" Verified chr4:539800-540411 539800-540411 98.7% 377.46 344.35 443.68 405.60 592.67 374.15 360.90 424.64 483.41 1.33 1.72 2.00 0.19 -0.40 Matched[998]
YDR042C Putative protein of unknown function; expression is increased in ssu72-ts69 mutant Uncharacterized chr4:540598-541200 540598-541200 99.0% 18.43 10.05 20.10 3.35 13.40 8.38 14.24 11.73 10.89 0.05 0.05 0.05 -0.11 -0.41 Frag<80[999,1000]
YDR043C NRG1 Transcriptional repressor that recruits the Cyc8p-Tup1p complex to promoters; mediates glucose repression and negatively regulates a variety of processes including filamentous growth and alkaline pH response Verified chr4:542672-543367 542672-543367 99.2% 75.29 86.87 83.98 85.42 412.64 220.08 81.08 84.70 316.36 0.30 0.34 1.31 1.90 1.78 Matched[1002]
YDR044W HEM13 "Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; localizes to the mitochondrial inner membrane; transcription is repressed by oxygen and heme (via Rox1p and Hap1p)" Verified chr4:546640-547626 546640-547626 98.7% 317.10 3603.03 334.54 379.70 188.82 163.17 1960.06 357.12 176.00 7.24 1.45 0.73 -1.02 -0.53 Matched[1006]
YDR045C RPC11 RNA polymerase III subunit C11; mediates pol III RNA cleavage activity and is important for termination of transcription; homologous to TFIIS Verified chr4:547976-548308 547976-548308 99.1% 430.30 275.76 339.39 248.48 145.45 93.94 353.03 293.94 119.70 1.30 1.19 0.50 -1.30 -1.81 Matched[1007]
YDR046C BAP3 "Amino acid permease involved in the uptake of cysteine, leucine, isoleucine and valine" Verified chr4:548760-550574 548760-550574 98.8% 405.31 601.55 428.16 296.03 129.34 83.63 503.43 362.10 106.48 1.86 1.47 0.44 -1.77 -1.50 Frag>80[1008,1009]
YDR047W HEM12 "Uroporphyrinogen decarboxylase, catalyzes the fifth step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; activity inhibited by Cu2+, Zn2+, Fe2+, Fe3+ and sulfhydryl-specific reagents" Verified chr4:551858-552946 551858-552946 98.4% 528.09 599.93 532.75 487.97 380.67 325.62 564.01 510.36 353.15 2.08 2.07 1.46 -0.53 -0.43 Matched[1010]
YDR049W Zinc finger protein; putative transcription factor that may interact with proteins involved in histone acetylation or deacetylation; may be involved in altering acetylation on histone lysines Uncharacterized chr4:553252-555150 553252-555150 98.4% 111.33 105.98 87.24 80.29 67.98 66.37 108.65 83.76 67.17 0.40 0.34 0.28 -0.32 -0.01 Matched[1011]
YDR048C "Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:553082-553396 553082-553396 98.7% 48.26 28.96 28.96 28.96 19.31 57.92 38.61 28.96 38.61 0.14 0.12 0.16 0.42 1.00 Covered/w/another[1011]
YDR050C TPI1 "Triose phosphate isomerase, abundant glycolytic enzyme; mRNA half-life is regulated by iron availability; transcription is controlled by activators Reb1p, Gcr1p, and Rap1p through binding sites in the 5' non-coding region" Verified chr4:555724-556470 555724-556470 98.7% 26658.53 27607.52 25194.37 23705.81 18917.47 15431.96 27133.03 24450.09 17174.71 100.16 99.25 71.16 -0.51 -1.90 Frag>80[1012,1013,1014]
YDR051C Protein of unknown function; interacts with Hsp82p in two-hybrid assay; deletion confers sensitivity to Nickel Uncharacterized chr4:557054-558058 557054-558058 99.3% 232.50 219.48 212.46 199.43 266.58 168.36 225.99 205.95 217.47 0.83 0.84 0.90 0.08 -0.25 Matched[1015]
YDR053W Putative protein of unknown function; open reading frame overlaps 5' end of essential DBF4 gene encoding the regulatory subunit of the Cdc7p-Dbf4p kinase complex Dubious chr4:560247-560642 560247-560642 99.1% 109.60 127.44 94.31 99.41 56.07 107.05 118.52 96.86 81.56 0.44 0.39 0.34 -0.25 -0.03 Covered/w/another[1016]
YDR052C DBF4 "Regulatory subunit of Cdc7p-Dbf4p kinase complex, required for Cdc7p kinase activity and initiation of DNA replication; phosphorylates the Mcm2-7 family of proteins; cell cycle regulated" Verified chr4:558509-560623 558509-560623 99.2% 164.43 161.57 159.19 143.46 128.68 122.96 163.00 151.32 125.82 0.60 0.61 0.52 -0.27 0.19 Matched[1016]
YDR054C CDC34 "Ubiquitin-conjugating enzyme (E2) and catalytic subunit of SCF ubiquitin-protein ligase complex (together with Skp1p, Rbx1p, Cdc53p, and an F-box protein) that regulates cell cycle progression by targeting key substrates for degradation" Verified chr4:561438-562325 561438-562325 99.1% 412.32 455.49 517.96 479.34 699.70 499.79 433.91 498.65 599.74 1.60 2.02 2.48 0.27 0.59 Matched[1018]
YDR055W PST1 "Cell wall protein that contains a putative GPI-attachment site; secreted by regenerating protoplasts; up-regulated by activation of the cell integrity pathway, as mediated by Rlm1p; upregulated by cell wall damage via disruption of FKS1" Verified chr4:563525-564859 563525-564859 99.2% 476.45 646.34 410.00 343.56 1382.54 908.35 561.40 376.78 1145.45 2.07 1.53 4.75 1.60 1.56 Frag>80[1020,1021,1022]
YDR056C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic retiuculum; YDR056C is not an essential protein Uncharacterized chr4:565021-565638 565021-565638 99.4% 527.33 784.48 460.60 460.60 362.95 278.31 655.91 460.60 320.63 2.42 1.87 1.33 -0.52 -0.40 Frag>80[1022,1023]
YDR057W YOS9 "ER quality-control lectin; integral subunit of the HRD ligase; serves as a receptor for misfolded N-glycosylated proteins, participates in their targeting to ERAD; member of the OS-9 protein family" Verified chr4:565925-567553 565925-567553 98.7% 79.03 110.14 89.60 74.05 82.76 60.36 94.58 81.83 71.56 0.35 0.33 0.30 -0.19 0.41 Matched[1024]
YDR058C TGL2 Protein with lipolytic activity towards triacylglycerols and diacylglycerols when expressed in E. coli; role in yeast lipid degradation is unclear Verified chr4:567721-568701 567721-568701 99.1% 92.56 117.24 78.16 74.05 229.34 167.63 104.90 76.10 198.48 0.39 0.31 0.82 1.38 0.83 Matched[1025]
YDR059C UBC5 "Ubiquitin-conjugating enzyme that mediates selective degradation of short-lived and abnormal proteins, central component of the cellular stress response; expression is heat inducible" Verified chr4:569232-569768 569232-569631,569722-569768 98.3% 156.97 179.72 152.42 159.24 345.78 220.66 168.34 155.83 283.22 0.62 0.63 1.17 0.86 0.40 Matched[1026]
YDR060W MAK21 "Constituent of 66S pre-ribosomal particles, required for large (60S) ribosomal subunit biogenesis; involved in nuclear export of pre-ribosomes; required for maintenance of dsRNA virus; homolog of human CAATT-binding protein" Verified chr4:570646-573723 570646-573723 98.6% 432.15 223.98 249.67 230.90 26.35 11.86 328.06 240.28 19.10 1.21 0.98 0.08 -3.65 -2.31 Matched[1028]
YDR061W Protein with similarity to ATP-binding cassette (ABC) transporter family members; lacks predicted membrane-spanning regions; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance Uncharacterized chr4:574161-575780 574161-575780 98.5% 147.32 166.75 154.21 129.76 164.87 110.33 157.03 141.99 137.60 0.58 0.58 0.57 -0.05 0.14 Matched[1029]
YDR062W LCB2 "Component of serine palmitoyltransferase, responsible along with Lcb1p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine" Verified chr4:576471-578156 576471-578156 98.9% 871.16 744.56 738.56 707.36 407.38 367.18 807.86 722.96 387.28 2.98 2.93 1.60 -0.90 -0.65 Covered/w/another[1030]
YDR063W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YDR063W is not an essential gene Uncharacterized chr4:578661-579110 578661-579110 98.5% 430.87 460.19 439.89 446.66 882.04 588.78 445.53 443.27 735.41 1.64 1.80 3.05 0.73 0.65 Covered/w/another[1030]
YDR064W RPS13 Protein component of the small (40S) ribosomal subunit; has similarity to E. coli S15 and rat S13 ribosomal proteins Verified chr4:579456-580450 579456-579476,580016-580450 98.9% 9975.61 8093.13 8341.46 6736.14 2549.89 1920.18 9034.37 7538.80 2235.03 33.35 30.60 9.26 -1.75 -1.80 Matched[1031]
YDR065W "Protein of unknown function, required for vacuolar acidification; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr4:580685-581782 580685-581782 98.7% 55.35 76.57 55.35 38.74 47.97 40.59 65.96 47.05 44.28 0.24 0.19 0.18 -0.09 -0.28 Covered/w/another[1032]
YDR066C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YDR066C is not an essential gene Uncharacterized chr4:581906-582496 581906-582496 99.2% 71.61 97.19 73.32 54.56 104.01 54.56 84.40 63.94 79.28 0.31 0.26 0.33 0.31 0.39 Covered/w/another[1032]
YDR067C "Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts" Uncharacterized chr4:582789-583463 582789-583463 99.4% 162.52 184.89 126.74 125.25 250.50 140.16 173.71 125.99 195.33 0.64 0.51 0.81 0.63 0.52 Covered/w/another[1032]
YDR068W DOS2 "Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" Verified chr4:583711-584643 583711-584643 98.2% 362.23 280.40 302.22 305.50 325.14 218.21 321.32 303.86 271.67 1.19 1.23 1.13 -0.16 -0.29 Matched[1033]
YDR069C DOA4 "Ubiquitin isopeptidase, required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates, acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins en route to the vacuole" Verified chr4:584937-587717 584937-587717 99.1% 64.61 77.31 68.96 67.51 109.62 132.12 70.96 68.24 120.87 0.26 0.28 0.50 0.82 1.12 Matched[1034]
YDR070C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr4:588096-588377 588096-588377 99.0% 25.06 229.15 71.61 157.54 3723.71 2259.29 127.11 114.58 2991.50 0.47 0.47 12.39 4.71 3.69 Matched[1035]
YDR071C PAA1 "Polyamine acetyltransferase; acetylates polyamines (e.g. putrescine, spermidine, spermine) and also aralkylamines (e.g. tryptamine, phenylethylamine); may be involved in transcription and/or DNA replication" Verified chr4:588825-589400 588825-589400 99.2% 1165.52 1006.27 1205.78 997.52 1450.78 829.52 1085.90 1101.65 1140.15 4.01 4.47 4.72 0.05 -0.15 Frag>80[1036,1037,1038]
YDR072C IPT1 "Inositolphosphotransferase 1, involved in synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C), which is the most abundant sphingolipid in cells, mutation confers resistance to the antifungals syringomycin E and DmAMP1 in some growth media" Verified chr4:589759-591342 589759-591342 98.7% 326.94 335.89 397.95 303.90 260.40 147.79 331.41 350.93 204.09 1.22 1.42 0.85 -0.78 -0.58 Frag>80[1038,1039,1040]
YDR073W SNF11 Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; interacts with a highly conserved 40-residue sequence of Snf2p Verified chr4:592436-592945 592436-592945 91.6% 284.57 286.71 263.17 233.22 442.90 220.38 285.64 248.19 331.64 1.05 1.01 1.37 0.42 0.46 Covered[1041]
YDR074W TPS2 "Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway" Verified chr4:593890-596580 593890-596580 98.8% 243.83 431.59 578.34 691.60 2341.56 2781.05 337.71 634.97 2561.31 1.25 2.58 10.61 2.01 1.95 Matched[1043]
YDR075W PPH3 Catalytic subunit of an evolutionarily conserved protein phosphatase complex containing Psy2p and the regulatory subunit Psy4p; required for cisplatin resistance; involved in activation of Gln3p Verified chr4:597153-598079 597153-598079 98.6% 99.55 113.78 86.43 92.99 40.48 12.03 106.66 89.71 26.26 0.39 0.36 0.11 -1.77 -1.03 Matched[1044]
YDR076W RAD55 Protein that stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; forms heterodimer with Rad57p Verified chr4:598465-599685 598465-599685 98.7% 50.61 59.74 34.02 26.55 48.95 33.19 55.18 30.29 41.07 0.20 0.12 0.17 0.44 -0.33 Covered[1045]
YDR077W SED1 "Major stress-induced structural GPI-cell wall glycoprotein in stationary-phase cells, associates with translating ribosomes, possible role in mitochondrial genome maintenance; ORF contains two distinct variable minisatellites" Verified chr4:600790-601806 600790-601806 75.1% 9042.74 14540.69 11766.17 10875.39 16162.44 17142.29 11791.71 11320.78 16652.37 43.53 45.95 69.00 0.56 -0.10 Matched[1046]
YDR078C SHU2 "Protein of unassigned function involved in mutation suppression, important for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation; associates with Shu1p, Psy3p, and Csm2p" Verified chr4:602195-602866 602195-602866 99.4% 101.84 79.38 74.88 50.92 110.83 38.94 90.61 62.90 74.88 0.33 0.26 0.31 0.25 -1.03 Matched[1047]
YDR079W PET100 "Chaperone that specifically facilitates the assembly of cytochrome c oxidase, integral to the mitochondrial inner membrane; interacts with a subcomplex of subunits VII, VIIa, and VIII (Cox7p, Cox9p, and Cox8p) but not with the holoenzyme" Verified chr4:603061-603396 603061-603396 98.3% 290.58 360.20 281.50 354.14 665.91 320.85 325.39 317.82 493.38 1.20 1.29 2.04 0.63 -0.14 Matched[1048]
YDR079C-A TFB5 Component of the RNA polymerase II general transcription and DNA repair factor TFIIH; involved in transcription initiation; homolog of the Chlamydomonas reinhardtii REX1-S protein which is involved in DNA repair Verified chr4:603590-603808 603590-603808 99.4% 192.99 119.47 192.99 170.02 372.20 151.64 156.23 181.50 261.92 0.58 0.74 1.09 0.53 -0.42 Matched[1049]
YDR080W VPS41 Vacuolar membrane protein that is a subunit of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex; essential for membrane docking and fusion at the Golgi-to-endosome and endosome-to-vacuole stages of protein transport Verified chr4:604005-606983 604005-606983 98.5% 95.06 82.79 80.41 65.76 119.59 116.18 88.93 73.08 117.89 0.33 0.30 0.49 0.69 0.77 Matched[1050]
YDR081C PDC2 "Transcription factor required for the synthesis of the glycolytic enzyme pyruvate decarboxylase, required for high level expression of both the THI and the PDC genes" Verified chr4:607301-610078 607301-610078 99.2% 138.66 127.77 106.35 97.64 59.17 58.80 133.21 102.00 58.98 0.49 0.41 0.24 -0.79 -0.57 Matched[1051]
YDR082W STN1 "Telomere end-binding and capping protein, plays a key role with Pol12p in linking telomerase action with completion of lagging strand synthesis, and in a regulatory step required for telomere capping" Verified chr4:610438-611922 610438-611922 98.8% 60.67 88.63 64.77 53.86 44.99 38.86 74.65 59.31 41.93 0.28 0.24 0.17 -0.50 -0.34 Covered/w/another[1052]
YDR083W RRP8 "Nucleolar protein involved in rRNA processing, pre-rRNA cleavage at site A2; also involved in telomere maintenance; mutation is synthetically lethal with a gar1 mutation" Verified chr4:612070-613248 612070-613248 98.5% 331.62 163.66 205.00 199.83 23.26 17.23 247.64 202.42 20.24 0.91 0.82 0.08 -3.32 -2.68 Covered/w/another[1052]
YDR084C TVP23 Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern Verified chr4:613402-614001 613402-614001 98.8% 307.02 366.06 318.83 418.36 479.09 323.89 336.54 368.59 401.49 1.24 1.50 1.66 0.12 0.23 Matched[1053]
YDR085C AFR1 "Alpha-factor pheromone receptor regulator, negatively regulates pheromone receptor signaling; required for normal mating projection (shmoo) formation; required for Spa2p to recruit Mpk1p to shmoo tip during mating; interacts with Cdc12p" Verified chr4:614285-616147 614285-616147 99.2% 53.55 76.27 93.58 90.33 318.60 210.42 64.91 91.96 264.51 0.24 0.37 1.10 1.52 1.62 Frag>80[1054,1055]
YDR086C SSS1 "Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) that forms a channel for passage of secretory proteins through the endoplasmic reticulum membrane, and of the Ssh1p complex (Ssh1p-Sbh2p-Sss1p); interacts with Ost4p and Wbp1p" Verified chr4:616925-617167 616925-617167 99.6% 2681.82 2371.90 2462.81 2276.86 2206.61 1227.27 2526.86 2369.83 1716.94 9.33 9.62 7.11 -0.46 -1.54 Matched[1056]
YDR087C RRP1 "Essential evolutionarily conserved nucleolar protein necessary for biogenesis of 60S ribosomal subunits and processing of pre-rRNAs to mature rRNAs, associated with several distinct 66S pre-ribosomal particles" Verified chr4:617467-618303 617467-618303 99.4% 254.81 146.63 159.86 139.42 18.03 8.41 200.72 149.64 13.22 0.74 0.61 0.05 -3.50 -2.82 Matched[1057]
YDR088C SLU7 "RNA splicing factor, required for ATP-independent portion of 2nd catalytic step of spliceosomal RNA splicing; interacts with Prp18p; contains zinc knuckle domain" Verified chr4:618494-619642 618494-619642 99.5% 127.70 112.83 116.33 97.08 138.19 101.46 120.26 106.71 119.83 0.44 0.43 0.50 0.17 0.18 Matched[1058]
YDR089W Protein of unknown function; deletion confers resistance to Nickel Uncharacterized chr4:622109-624718 622109-624718 99.1% 176.34 176.34 194.13 143.08 111.76 88.94 176.34 168.61 100.35 0.65 0.68 0.42 -0.75 -0.22
YDR090C Putative protein of unknown function Uncharacterized chr4:625063-625995 625063-625995 98.9% 110.50 118.08 132.17 95.33 75.83 74.75 114.29 113.75 75.29 0.42 0.46 0.31 -0.60 -0.24 Covered[1060]
YDR091C RLI1 Essential iron-sulfur protein required for ribosome biogenesis and translation initiation; facilitates binding of a multifactor complex (MFC) of translation initiation factors to the small ribosomal subunit; predicted ABC family ATPase Verified chr4:626705-628531 626705-628531 99.1% 448.31 316.36 340.10 291.51 41.96 36.44 382.33 315.80 39.20 1.41 1.28 0.16 -3.01 -2.16 Matched[1062]
YDR092W UBC13 Ubiquitin-conjugating enzyme involved in the error-free DNA postreplication repair pathway; interacts with Mms2p to assemble ubiquitin chains at the Ub Lys-63 residue; DNA damage triggers redistribution from the cytoplasm to the nucleus Verified chr4:629873-630602 629873-629902,630171-630602 98.6% 511.25 577.07 471.75 489.30 664.84 419.09 544.16 480.53 541.96 2.01 1.95 2.25 0.17 0.02 Matched[1063]
YDR093W DNF2 "Aminophospholipid translocase (flippase) that localizes primarily to the plasma membrane; contributes to endocytosis, protein transport and cell polarity; type 4 P-type ATPase" Verified chr4:631279-636117 631279-636117 98.6% 131.01 136.25 127.24 108.58 54.50 65.82 133.63 117.91 60.16 0.49 0.48 0.25 -0.97 -0.34 Matched[1064]
YDR094W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF DNF2" Dubious chr4:635837-636172 635837-636172 98.4% 275.31 302.53 347.91 229.93 220.85 151.27 288.92 288.92 186.06 1.07 1.17 0.77 -0.63 -0.25 Covered/w/another[1064]
YDR095C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:636114-636524 636114-636524 98.0% 14.89 29.78 29.78 17.37 29.78 22.34 22.34 23.58 26.06 0.08 0.10 0.11 0.14 0.12 Overlap[1064,1065]
YDR096W GIS1 JmjC domain-containing histone demethylase; transcription factor involved in the expression of genes during nutrient limitation; also involved in the negative regulation of DPP1 and PHR1 Verified chr4:637136-639820 637136-639820 99.1% 106.78 110.91 149.64 154.15 256.80 234.99 108.85 151.90 245.89 0.40 0.62 1.02 0.69 1.07 Matched[1065]
YDR097C MSH6 "Protein required for mismatch repair in mitosis and meiosis, forms a complex with Msh2p to repair both single-base & insertion-deletion mispairs; potentially phosphorylated by Cdc28p" Verified chr4:640106-643834 640106-643834 99.3% 113.46 73.75 79.42 77.26 22.69 15.40 93.60 78.34 19.04 0.35 0.32 0.08 -2.04 -1.75 Matched[1066]
YDR098C GRX3 Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage Verified chr4:644175-645032 644175-645032 99.1% 554.17 430.63 541.23 457.69 330.62 210.61 492.40 499.46 270.61 1.82 2.03 1.12 -0.88 -0.62 Frag>80[1067,1068]
YDR099W BMH2 "14-3-3 protein, minor isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling" Verified chr4:652777-654425 652777-652778,653521-654425 93.6% 1816.61 2084.04 1894.36 1871.98 2736.70 1930.89 1950.32 1883.17 2333.79 7.20 7.64 9.67 0.31 0.34 Matched[1071]
YDR100W TVP15 Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p Verified chr4:655010-655441 655010-655441 99.2% 410.89 602.33 501.95 480.93 1456.81 845.14 506.61 491.44 1150.97 1.87 1.99 4.77 1.23 0.72 Matched[1074]
YDR101C ARX1 Shuttling pre-60S factor; involved in the biogenesis of ribosomal large subunit biogenesis; interacts directly with Alb1; responsible for Tif6 recycling defects in absence of Rei1; associated with the ribosomal export complex Verified chr4:655683-657464 655683-657464 99.0% 305.63 151.40 176.91 129.85 15.31 3.40 228.51 153.38 9.36 0.84 0.62 0.04 -4.04 -3.73 Matched[1075]
YDR102C Dubious open reading frame; homozygous diploid deletion strain exhibits high budding index Dubious chr4:657645-657977 657645-657977 98.9% 15.18 15.18 12.14 9.11 27.32 12.14 15.18 10.63 19.73 0.06 0.04 0.08 0.89 -0.77
YDR103W STE5 "Pheromone-response scaffold protein; binds kinases Ste11p, Ste7p, and Fus3p to form a MAPK cascade complex that interacts with the plasma membrane, via a PH (pleckstrin homology) and PM/NLS domain, and with Ste4p-Ste18p, during signaling" Verified chr4:658347-661100 658347-661100 99.0% 113.75 115.22 92.83 91.37 113.02 97.97 114.48 92.10 105.49 0.42 0.37 0.44 0.20 0.60 Matched[1076]
YDR104C SPO71 "Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensable for both nuclear divisions during meiosis" Verified chr4:661170-664907 661170-664907 99.1% 36.70 40.75 28.06 30.76 32.92 23.21 38.72 29.41 28.06 0.14 0.12 0.12 -0.07 0.27 Frag>80[1077,1078]
YDR105C TMS1 "Vacuolar membrane protein of unknown function that is conserved in mammals; predicted to contain eleven transmembrane helices; interacts with Pdr5p, a protein involved in multidrug resistance" Verified chr4:665346-666767 665346-666767 99.0% 207.32 226.49 206.61 166.85 257.73 184.60 216.90 186.73 221.16 0.80 0.76 0.92 0.24 0.48 Frag>80[1078,1079]
YDR106W ARP10 "Component of the dynactin complex, localized to the pointed end of the Arp1p filament; may regulate membrane association of the complex" Verified chr4:667001-667855 667001-667855 98.7% 14.22 23.71 13.04 9.48 13.04 15.41 18.96 11.26 14.22 0.07 0.05 0.06 0.34 -0.37 Overlap[1079]
YDR107C Multispanning membrane protein of unknown function Uncharacterized chr4:669013-671031 669013-671031 98.9% 97.61 138.16 90.10 77.09 76.09 78.59 117.89 83.60 77.34 0.44 0.34 0.32 -0.11 0.22 Matched[1080]
YDR108W GSG1 "Subunit of TRAPP (transport protein particle), a multi-subunit complex involved in targeting and/or fusion of ER-to-Golgi transport vesicles with their acceptor compartment; protein has late meiotic role, following DNA replication" Verified chr4:671266-673362 671266-673362 98.9% 64.14 72.83 59.32 47.26 62.21 45.33 68.48 53.29 53.77 0.25 0.22 0.22 0.01 0.49 Covered/w/another[1081]
YDR109C Putative kinase Uncharacterized chr4:673517-675664 673517-675664 99.2% 57.75 62.91 55.40 44.60 66.67 66.67 60.33 50.00 66.67 0.22 0.20 0.28 0.42 1.00 Covered/w/another[1081]
YDR110W FOB1 Nucleolar protein required for DNA replication fork blocking and recombinational hotspot activities; binds to the replication fork barrier site in the rDNA region; related to retroviral integrases Verified chr4:676099-677799 676099-677799 98.6% 107.28 76.29 74.50 63.17 44.10 24.44 91.78 68.84 34.27 0.34 0.28 0.14 -1.01 -1.23 Matched[1082]
YDR112W "Hypothetical protein, null mutant displays increased levels of spontaneous Rad52 foci" Dubious chr4:679541-679849 679541-679849 99.3% 91.28 32.60 65.20 71.72 22.82 9.78 61.94 68.46 16.30 0.23 0.28 0.07 -2.07 -0.31 Covered/w/another[1083]
YDR111C ALT2 Putative alanine transaminase (glutamic pyruvic transaminase) Uncharacterized chr4:678238-679761 678238-679761 99.0% 135.92 86.86 116.03 88.18 53.71 38.46 111.39 102.11 46.08 0.41 0.41 0.19 -1.15 -1.08 Matched[1083]
YDR113C PDS1 "Securin that inhibits anaphase by binding separin Esp1p, also blocks cyclin destruction and mitotic exit, essential for cell cycle arrest in mitosis in the presence of DNA damage or aberrant mitotic spindles; also present in meiotic nuclei" Verified chr4:680493-681614 680493-681614 99.1% 104.29 139.35 133.05 124.96 133.05 80.91 121.82 129.01 106.98 0.45 0.52 0.44 -0.27 0.05 Frag>80[1084,1085]
YDR115W "Putative mitochondrial ribosomal protein of the large subunit, has similarity to E. coli L34 ribosomal protein; required for respiratory growth, as are most mitochondrial ribosomal proteins" Uncharacterized chr4:682172-682489 682172-682489 98.7% 449.10 484.14 500.07 410.88 818.58 449.10 466.62 455.47 633.84 1.72 1.85 2.63 0.48 -0.44 Matched[1086]
YDR114C Putative protein of unknown function; deletion mutant exhibits poor growth at elevated pH and calcium Uncharacterized chr4:681921-682223 681921-682223 97.9% 84.29 84.29 118.01 97.78 236.02 111.27 84.29 107.90 173.64 0.31 0.44 0.72 0.69 -0.77 Frag<80[1086]
YDR116C MRPL1 Mitochondrial ribosomal protein of the large subunit Verified chr4:682721-683578 682721-683578 99.1% 271.66 256.37 295.18 303.41 376.32 266.95 264.01 299.29 321.64 0.97 1.21 1.33 0.10 0.31 Matched[1087]
YDR117C TMA64 Protein of unknown function that associates with ribosomes; has a putative RNA binding domain Verified chr4:683943-685640 683943-685640 99.1% 177.65 185.96 188.34 188.34 152.69 96.25 181.80 188.34 124.47 0.67 0.76 0.52 -0.60 -0.17 Matched[1089]
YDR118W APC4 "Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" Verified chr4:685879-687837 685879-687837 98.8% 67.16 64.06 54.76 47.53 72.32 42.88 65.61 51.14 57.60 0.24 0.21 0.24 0.17 -0.25 Covered/w/another[1090]
YDR118W-A Dubious open reading frame; identified using a combination of expression profiling and mass spectrometry Dubious chr4:687765-687881 687765-687881 98.9% 112.31 120.95 60.48 51.84 120.95 60.48 116.63 56.16 90.71 0.43 0.23 0.38 0.69 NaN Covered/w/another[1090]
YDR119W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to vacuolar membrane; YDR119W is not an essential gene Uncharacterized chr4:688224-690530 688224-690530 98.9% 315.01 267.69 260.68 248.85 127.49 110.85 291.35 254.77 119.17 1.08 1.03 0.49 -1.10 -0.93 Covered/w/another[1090]
YDR119W-A Putative protein of unknown function Uncharacterized chr4:691011-691211 691011-691211 98.2% 81.06 263.46 359.72 567.45 2659.91 1099.43 172.26 463.58 1879.67 0.64 1.88 7.79 2.02 NaN Matched[1091]
YDR120C TRM1 "tRNA methyltransferase, localizes to both the nucleus and mitochondrion to produce the modified base N2,N2-dimethylguanosine in tRNAs in both compartments" Verified chr4:691546-693258 691546-693258 99.1% 276.38 136.13 176.20 118.45 19.45 5.30 206.25 147.32 12.38 0.76 0.60 0.05 -3.57 -2.41 Matched[1092]
YDR121W DPB4 Shared subunit of DNA polymerase (II) epsilon and of ISW2/yCHRAC chromatin accessibility complex; involved in both chromosomal DNA replication and in inheritance of telomeric silencing Verified chr4:693582-694172 693582-694172 98.0% 212.42 221.05 181.33 174.43 67.35 27.63 216.74 177.88 47.49 0.80 0.72 0.20 -1.91 -1.35 Matched[1093]
YDR122W KIN1 Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; closely related to Kin2p Verified chr4:694697-697891 694697-697891 98.6% 164.50 194.35 194.35 212.77 308.36 355.04 179.43 203.56 331.70 0.66 0.83 1.37 0.70 1.30 Matched[1094]
YDR123C INO2 "Component of the heteromeric Ino2p/Ino4p basic helix-loop-helix transcription activator that binds inositol/choline-responsive elements (ICREs), required for derepression of phospholipid biosynthetic genes in response to inositol depletion" Verified chr4:698551-699465 698551-699465 98.8% 56.41 45.35 42.03 33.18 68.58 59.73 50.88 37.61 64.15 0.19 0.15 0.27 0.77 0.77 Matched[1095]
YDR124W Putative protein of unknown function; non-essential gene; expression is strongly induced by alpha factor Uncharacterized chr4:700312-701286 700312-701286 98.7% 62.35 68.59 51.96 42.61 120.55 84.18 65.47 47.29 102.36 0.24 0.19 0.42 1.11 0.52 Covered/w/another[1096]
YDR125C ECM18 "Protein of unknown function, similar to Rlp24p" Verified chr4:701394-702755 701394-702755 99.3% 28.83 36.97 26.62 31.79 73.20 68.76 32.90 29.20 70.98 0.12 0.12 0.29 1.28 1.39 Covered/w/another[1096]
YDR126W SWF1 "Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on all SNAREs; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; may have a role in vacuole fusion" Verified chr4:703231-704241 703231-704241 99.0% 57.93 69.92 49.94 24.97 18.98 6.99 63.93 37.46 12.98 0.24 0.15 0.05 -1.53 -1.49 Covered[1097]
YDR127W ARO1 "Pentafunctional arom protein, catalyzes steps 2 through 6 in the biosynthesis of chorismate, which is a precursor to aromatic amino acids" Verified chr4:704481-709247 704481-709247 98.8% 298.24 402.03 270.00 243.26 86.82 97.86 350.13 256.63 92.34 1.29 1.04 0.38 -1.47 -0.44 Frag<80[1098]
YDR128W Putative protein of unknown function Uncharacterized chr4:709546-712992 709546-712992 98.6% 127.04 112.04 96.46 99.69 60.29 62.34 119.54 98.08 61.32 0.44 0.40 0.25 -0.68 -0.21 Matched[1099]
YDR129C SAC6 "Fimbrin, actin-bundling protein; cooperates with Scp1p (calponin/transgelin) in the organization and maintenance of the actin cytoskeleton" Verified chr4:713337-715376 713337-715244,715356-715376 99.1% 498.82 451.24 618.04 602.88 1164.97 1161.31 475.03 610.46 1163.14 1.75 2.48 4.82 0.93 1.36 Matched[1100]
YDR130C FIN1 "Spindle pole body-related intermediate filament protein, forms cell cycle-specific filaments between spindle pole bodies in mother and daughter cells, able to self-assemble, expression induced during S/G2, localization cell-cycle dependent" Verified chr4:715744-716619 715744-716619 99.3% 133.34 116.10 117.25 97.71 157.48 106.90 124.72 107.48 132.19 0.46 0.44 0.55 0.30 0.78 Covered/w/another[1101]
YDR131C "F-box protein, substrate-specific adaptor subunit that recruits substrates to a core ubiquitination complex" Uncharacterized chr4:716787-718457 716787-718457 99.1% 54.33 56.74 53.73 54.93 93.57 63.38 55.54 54.33 78.47 0.21 0.22 0.33 0.53 0.66 Covered/w/another[1101]
YDR132C Putative protein of unknown function Uncharacterized chr4:718813-720300 718813-720300 99.1% 55.62 64.44 36.63 63.08 48.84 37.30 60.03 49.85 43.07 0.22 0.20 0.18 -0.21 -0.83 Matched[1102]
YDR133C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps YDR134C" Dubious chr4:720959-721294 720959-721294 96.1% 6873.52 10256.07 10067.11 8806.40 17776.97 8831.18 8564.79 9436.76 13304.08 31.62 38.31 55.12 0.50 -1.79 Matched[1104]
YDR135C YCF1 "Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR" Verified chr4:723001-727548 723001-727548 99.1% 225.34 185.20 219.79 160.80 188.52 121.99 205.27 190.30 155.25 0.76 0.77 0.64 -0.29 -0.95 Matched[1106]
YDR137W RGP1 Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6p Verified chr4:728256-730247 728256-730247 98.8% 96.08 84.39 90.49 73.71 95.06 57.95 90.23 82.10 76.51 0.33 0.33 0.32 -0.10 -0.04 Matched[1107]
YDR136C VPS61 "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 4% of ORF overlaps the verified gene RGP1; deletion causes a vacuolar protein sorting defect" Dubious chr4:727708-728280 727708-728280 98.9% 10.59 14.12 10.59 7.06 10.59 5.30 12.36 8.83 7.94 0.05 0.04 0.03 -0.15 0.11 Overlap[1107]
YDR138W HPR1 "Subunit of THO/TREX complexes that couple transcription elongation with mitotic recombination and with mRNA metabolism and export, subunit of an RNA Pol II complex; regulates lifespan; involved in telomere maintenance; similar to Top1p" Verified chr4:730575-732833 730575-732833 98.8% 100.32 88.67 74.79 68.52 39.86 20.15 94.50 71.66 30.01 0.35 0.29 0.12 -1.26 -1.69 Matched[1108]
YDR139C RUB1 "Ubiquitin-like protein with similarity to mammalian NEDD8; conjugation (neddylation) substrates include the cullins Cdc53p, Rtt101p, and Cul3p; activated by Ula1p and Uba3p (E1 enzyme pair); conjugation mediated by Ubc12p (E2 enzyme)" Verified chr4:733615-733921 733615-733699,733773-733921 99.1% 607.98 767.52 500.18 577.79 845.13 431.19 687.75 538.99 638.16 2.54 2.19 2.64 0.24 -0.44 Matched[1109]
YDR140W MTQ2 S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; methylates release factor eRF1 (Sup45p) in vitro; is not an essential gene; similar to E.coli PrmC Verified chr4:734135-734800 734135-734800 98.7% 159.75 159.75 153.66 108.02 130.84 97.37 159.75 130.84 114.10 0.59 0.53 0.47 -0.20 0.18 Matched[1110]
YDR141C DOP1 "Protein of unknown function, essential for viability, involved in establishing cellular polarity and morphogenesis; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr4:734898-739994 734898-739994 99.1% 92.21 98.94 76.98 82.91 89.64 100.33 95.58 79.95 94.98 0.35 0.32 0.39 0.25 0.66 Frag>80[1111]
YDR142C PEX7 Peroxisomal signal receptor for the N-terminal nonapeptide signal (PTS2) of peroxisomal matrix proteins; WD repeat protein; defects in human homolog cause lethal rhizomelic chondrodysplasia punctata (RCDP) Verified chr4:740470-741597 740470-741597 99.1% 86.78 84.99 72.46 76.04 103.78 74.25 85.88 74.25 89.01 0.32 0.30 0.37 0.26 0.40 Matched[1112]
YDR143C SAN1 "Ubiquitin-protein ligase, involved in the proteasome-dependent degradation of aberrant nuclear proteins; san1 mutations suppress sir4, spt16, and cdc68 mutations, suggesting a role in chromatin silencing" Verified chr4:742039-743871 742039-743871 98.7% 158.67 153.69 128.26 86.80 90.11 68.55 156.18 107.53 79.33 0.58 0.44 0.33 -0.44 0.26 Covered/w/another[1113]
YDR144C MKC7 GPI-anchored aspartyl protease (yapsin) involved in protein processing; shares functions with Yap3p and Kex2p Verified chr4:744308-746098 744308-746098 98.8% 174.65 113.04 153.74 114.17 39.56 31.65 143.85 133.96 35.61 0.53 0.54 0.15 -1.91 -1.39 Covered/w/another[1113]
YDR145W TAF12 "Subunit (61/68 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H2A" Verified chr4:746735-748354 746735-748354 96.2% 314.56 277.33 270.91 268.98 256.15 233.68 295.95 269.95 244.91 1.09 1.10 1.01 -0.14 0.17 Covered/w/another[1114]
YDR146C SWI5 Transcription factor that activates transcription of genes expressed at the M/G1 phase boundary and in G1 phase; localization to the nucleus occurs during G1 and appears to be regulated by phosphorylation by Cdc28p kinase Verified chr4:748610-750739 748610-750739 99.1% 197.94 255.24 224.94 195.10 193.68 161.48 226.59 210.02 177.58 0.84 0.85 0.74 -0.24 -0.08 Covered/w/another[1114]
YDR147W EKI1 "Ethanolamine kinase, primarily responsible for phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway; also exhibits choline kinase activity" Verified chr4:751628-753232 751628-753232 98.9% 108.37 134.84 96.40 80.02 74.98 47.26 121.60 88.21 61.12 0.45 0.36 0.25 -0.53 -0.04 Matched[1115]
YDR148C KGD2 "Dihydrolipoyl transsuccinylase, component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes the oxidative decarboxylation of alpha-ketoglutarate to succinyl-CoA in the TCA cycle; phosphorylated" Verified chr4:753672-755063 753672-755063 98.9% 471.39 591.96 615.92 647.16 547.65 583.97 531.67 631.54 565.81 1.96 2.56 2.34 -0.16 0.29 Frag>80[1116,1117]
YDR150W NUM1 "Protein required for nuclear migration, localizes to the mother cell cortex and the bud tip; may mediate interactions of dynein and cytoplasmic microtubules with the cell cortex" Verified chr4:755625-763871 755625-763871 72.4% 141.47 142.14 129.58 129.75 93.42 160.89 141.81 129.67 127.16 0.52 0.53 0.53 -0.03 0.58 Frag<80[1118,1119]
YDR149C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:755552-756259 755552-756259 98.4% 53.13 44.51 31.59 47.38 27.28 80.41 48.82 39.49 53.84 0.18 0.16 0.22 0.45 0.13 Covered[1118]
YDR151C CTH1 "Member of the CCCH zinc finger family; has similarity to mammalian Tis11 protein, which activates transcription and also has a role in mRNA degradation; may function with Tis11p in iron homeostasis" Verified chr4:764175-765152 764175-765152 98.9% 164.36 145.75 161.25 139.55 485.83 457.92 155.05 150.40 471.88 0.57 0.61 1.96 1.65 2.03 Covered[1120]
YDR152W GIR2 "Highly-acidic cytoplasmic RWD domain-containing protein of unknown function, sensitive to proteolysis, N-terminal region has high content of acidic amino acid residues, putative IUP (intrinsically unstructured protein)" Verified chr4:765703-766500 765703-766500 98.3% 367.31 288.23 330.32 266.55 179.83 114.78 327.77 298.44 147.31 1.21 1.21 0.61 -1.02 -0.82 Frag>80[1121,1122]
YDR153C ENT5 "Protein containing an N-terminal epsin-like domain involved in clathrin recruitment and traffic between the Golgi and endosomes; associates with the clathrin adaptor Gga2p, clathrin adaptor complex AP-1, and clathrin" Verified chr4:766733-767968 766733-767968 99.1% 186.98 174.73 175.55 181.26 221.27 165.75 180.85 178.40 193.51 0.67 0.72 0.80 0.12 0.50 Matched[1123]
YDR154C "Dubious open reading frame, null mutant exhibits synthetic phenotype with alpha-synuclein" Dubious chr4:768400-768750 768400-768750 94.8% 9719.01 10707.74 9974.46 8850.49 22271.98 13896.32 10213.37 9412.47 18084.15 37.70 38.21 74.93 0.94 -0.46 Matched[1124]
YDR155C CPR1 "Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds the drug cyclosporin A" Verified chr4:768509-768997 768509-768997 95.7% 9976.33 10822.11 10352.23 9113.46 21795.85 14839.55 10399.22 9732.85 18317.70 38.39 39.51 75.90 0.91 -0.71 Matched[1124]
YDR156W RPA14 RNA polymerase I subunit A14 Verified chr4:769522-769935 769522-769935 98.5% 284.34 254.93 269.64 210.81 171.59 112.76 269.64 240.22 142.17 1.00 0.98 0.59 -0.76 -0.35 Frag>80[1125,1126]
YDR157W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:769928-770329 769928-770329 99.4% 70.04 72.55 60.04 60.04 40.03 25.02 71.29 60.04 32.52 0.26 0.24 0.13 -0.88 -0.45 Frag<80[1125,1126]
YDR158W HOM2 "Aspartic beta semi-aldehyde dehydrogenase, catalyzes the second step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis" Verified chr4:770354-771451 770354-771451 98.8% 1714.35 2404.15 1611.99 1737.41 1256.95 969.22 2059.25 1674.70 1113.08 7.60 6.80 4.61 -0.59 -0.29 Matched[1127]
YDR159W SAC3 "Nuclear pore-associated protein, forms a complex with Thp1p that is involved in transcription and in mRNA export from the nucleus" Verified chr4:771874-775779 771874-775779 98.9% 136.42 126.07 96.56 84.39 85.17 90.86 131.25 90.47 88.01 0.48 0.37 0.36 -0.04 0.24 Matched[1128]
YDR160W SSY1 "Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes" Verified chr4:776160-778718 776160-778718 98.8% 70.38 76.70 76.70 64.84 60.10 66.42 73.54 70.77 63.26 0.27 0.29 0.26 -0.16 0.30 Matched[1129]
YDR161W Putative protein of unknown function; non-essential gene; proposed function in rRNA and ribosome biosynthesis based on transcriptional co-regulation Uncharacterized chr4:779040-780203 779040-780203 98.5% 294.74 182.25 220.62 158.70 15.70 3.49 238.49 189.66 9.59 0.88 0.77 0.04 -4.31 -3.09 Matched[1130]
YDR162C NBP2 "Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regulates Hog1p by recruitment of phosphatase Ptc1p the Pbs2p-Hog1p complex, found in the nucleus and cytoplasm, contains an SH3 domain that binds Pbs2p" Verified chr4:780387-781097 780387-781097 99.4% 121.63 103.24 123.04 117.38 189.51 124.45 112.43 120.21 156.98 0.42 0.49 0.65 0.39 0.28 Matched[1131]
YDR163W CWC15 "Non-essential protein involved in pre-mRNA splicing, component of a complex containing Cef1p; has similarity to S. pombe Cwf15p" Verified chr4:781420-781947 781420-781947 98.0% 191.29 210.61 154.58 152.64 241.53 183.56 200.95 153.61 212.54 0.74 0.62 0.88 0.47 0.28 Covered/w/another[1132]
YDR164C SEC1 Sm-like protein involved in docking and fusion of exocytic vesicles through binding to assembled SNARE complexes at the membrane; localization to sites of secretion (bud neck and bud tip) is dependent on SNARE function Verified chr4:782038-784212 782038-784212 99.2% 141.87 148.36 145.11 140.48 92.72 90.41 145.11 142.79 91.56 0.54 0.58 0.38 -0.64 -0.20 Matched[1132]
YDR165W TRM82 Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p that catalyzes 7-methylguanosine modification of tRNA Verified chr4:784868-786202 784868-786202 99.0% 295.75 193.64 220.87 154.31 32.53 7.56 244.70 187.59 20.04 0.90 0.76 0.08 -3.23 -2.36 Matched[1133]
YDR166C SEC5 "Essential 107kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis" Verified chr4:786303-789218 786303-789218 99.3% 101.87 112.23 104.29 92.55 111.19 105.67 107.05 98.42 108.43 0.40 0.40 0.45 0.14 0.59 Matched[1134]
YDR167W TAF10 "Subunit (145 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification" Verified chr4:789446-790066 789446-790066 98.2% 326.47 280.54 277.26 318.27 241.16 154.21 303.51 297.76 197.69 1.12 1.21 0.82 -0.59 -0.93 Matched[1135]
YDR168W CDC37 Essential Hsp90p co-chaperone; necessary for passage through the START phase of the cell cycle; stabilizes protein kinase nascent chains and participates along with Hsp90p in their folding Verified chr4:790325-791845 790325-791845 98.7% 412.45 379.80 362.48 388.46 810.24 569.03 396.12 375.47 689.64 1.46 1.52 2.86 0.88 0.69 Matched[1136]
YDR169C STB3 Protein that binds Sin3p in a two-hybrid assay Verified chr4:792345-793886 792345-793886 98.9% 209.84 258.37 224.92 206.56 335.09 363.94 234.10 215.74 349.52 0.86 0.88 1.45 0.70 1.12 Matched[1138]
YDR169C-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr4:794571-794720 794571-794720 98.8% 13.50 27.00 20.25 0.00 6.75 13.50 20.25 10.13 10.13 0.07 0.04 0.04 0.00 NaN
YDR170C SEC7 "Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles" Verified chr4:796190-802219 796190-802219 98.5% 253.11 251.09 238.64 224.33 113.60 189.16 252.10 231.49 151.38 0.93 0.94 0.63 -0.61 -0.19 Frag>80[1140,1141]
YDR171W HSP42 Small heat shock protein (sHSP) with chaperone activity; forms barrel-shaped oligomers that suppress unfolded protein aggregation; involved in cytoskeleton reorganization after heat shock Verified chr4:806618-807745 806618-807745 98.4% 149.54 316.19 390.06 567.53 15191.65 12123.41 232.87 478.79 13657.53 0.86 1.94 56.59 4.83 3.40 Frag>80[1143,1144,1145]
YDR172W SUP35 "Translation termination factor eRF3; altered protein conformation creates the [PSI(+)] prion, a dominant cytoplasmically inherited protein aggregate that alters translational fidelity and creates a nonsense suppressor phenotype" Verified chr4:808321-810378 808321-810378 98.6% 603.50 466.05 552.26 526.64 221.69 295.59 534.77 539.45 258.64 1.97 2.19 1.07 -1.06 -0.23 Matched[1146]
YDR173C ARG82 "Inositol polyphosphate multikinase (IPMK), sequentially phosphorylates Ins(1,4,5)P3 to form Ins(1,3,4,5,6)P5; putative nuclear lipid inositol PI3-kinase; regulates arginine-, phosphate-, and nitrogen-responsive genes" Verified chr4:810562-811629 810562-811629 98.6% 55.10 79.80 61.75 47.50 145.35 61.75 67.45 54.62 103.55 0.25 0.22 0.43 0.92 0.32 Matched[1147]
YDR174W HMO1 "Chromatin associated high mobility group (HMG) family member involved in genome maintenance; rDNA-binding component of the Pol I transcription system; associates with a 5'-3' DNA helicase and Fpr1p, a prolyl isomerase" Verified chr4:812107-812847 812107-812847 97.6% 1288.33 1147.33 1249.63 998.04 1429.33 934.45 1217.83 1123.83 1181.89 4.50 4.56 4.90 0.07 -0.00 Frag>80[1148,1149]
YDR175C RSM24 Mitochondrial ribosomal protein of the small subunit Verified chr4:813190-814149 813190-814149 99.3% 224.45 219.20 228.64 230.74 220.25 125.86 221.82 229.69 173.05 0.82 0.93 0.72 -0.41 -0.29 Matched[1150]
YDR176W NGG1 "Transcriptional regulator involved in glucose repression of Gal4p-regulated genes; component of transcriptional adaptor and histone acetyltransferase complexes, the ADA complex, the SAGA complex, and the SLIK complex" Verified chr4:814449-816557 814449-816557 98.5% 207.49 210.38 178.61 172.35 167.05 136.72 208.94 175.48 151.89 0.77 0.71 0.63 -0.21 -0.03 Matched[1151]
YDR177W UBC1 Ubiquitin-conjugating enzyme that mediates selective degradation of short-lived and abnormal proteins; plays a role in vesicle biogenesis and ER-associated protein degradation (ERAD); component of the cellular stress response Verified chr4:816875-817522 816875-817522 98.7% 676.78 561.12 639.27 448.58 908.11 426.70 618.95 543.93 667.40 2.28 2.21 2.77 0.30 0.09 Matched[1152]
YDR178W SDH4 "Membrane anchor subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone" Verified chr4:817947-818492 817947-818492 98.8% 470.62 635.53 631.82 839.34 1563.81 1172.86 553.08 735.58 1368.33 2.04 2.99 5.67 0.90 0.83 Matched[1153]
YDR179C CSN9 "Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in adaptation to pheromone signaling" Verified chr4:818705-819193 818705-819193 99.7% 106.70 57.46 61.56 61.56 98.50 61.56 82.08 61.56 80.03 0.30 0.25 0.33 0.38 -0.38 Matched[1154]
YDR179W-A Putative protein of unknown function Uncharacterized chr4:819430-820821 819430-820821 99.1% 70.32 52.92 52.19 40.60 45.67 27.55 61.62 46.40 36.61 0.23 0.19 0.15 -0.34 -0.93 Matched[1155]
YDR180W SCC2 "Subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for the loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during DSB repair via histone H2AX" Verified chr4:821292-825773 821292-825773 99.0% 50.69 37.39 33.57 22.30 19.15 16.44 44.04 27.93 17.80 0.16 0.11 0.07 -0.65 -0.68 Frag<80[1156]
YDR181C SAS4 "Subunit of the SAS complex (Sas2p, Sas4p, Sas5p), which acetylates free histones and nucleosomes and regulates transcriptional silencing; required for the HAT activity of Sas2p" Verified chr4:825907-827352 825907-827352 99.4% 84.92 94.66 105.80 105.10 123.20 77.96 89.79 105.45 100.58 0.33 0.43 0.42 -0.07 0.20 Matched[1157]
YDR182W CDC1 "Putative membrane protein of unknown function involved in Mn2+ homeostasis; mutants display actin and general growth defects, heterogeneous cell cycle arrests, and pleiotropic defects in cell cycle progression and organelle distribution" Verified chr4:827579-829054 827579-829054 98.8% 261.19 282.44 270.79 257.76 279.01 191.27 271.82 264.27 235.14 1.00 1.07 0.97 -0.17 0.43 Matched[1158]
YDR182W-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr4:829148-829351 829148-829351 96.6% 20.30 25.38 20.30 15.23 60.90 10.15 22.84 17.76 35.53 0.08 0.07 0.15 1.00 NaN Matched[1159]
YDR183W PLP1 "Protein with a possible role in folding of beta-tubulin; has weak similarity to phosducins, which are G-protein regulators" Verified chr4:829582-830274 829582-830274 98.6% 77.57 80.49 65.86 64.39 136.11 67.32 79.03 65.13 101.71 0.29 0.26 0.42 0.64 0.34 Covered/w/another[1160]
YDR183C-A Dubious open reading frame unlikely to encode a functional protein; identified by fungal homology and RT-PCR Dubious chr4:830394-830651 830394-830651 99.2% 160.13 82.02 66.40 31.24 11.72 11.72 121.07 48.82 11.72 0.45 0.20 0.05 -2.06 NaN Covered/w/another[1160]
YDR184C ATC1 "Nuclear protein, possibly involved in regulation of cation stress responses and/or in the establishment of bipolar budding pattern" Verified chr4:830626-831510 830626-831510 99.2% 140.04 70.59 84.25 46.68 10.25 17.08 105.31 65.46 13.66 0.39 0.27 0.06 -2.26 -2.25 Covered/w/another[1160]
YDR185C "Mitochondrial protein of unknown function; has similarity to Ups1p, which is involved in regulation of alternative topogenesis of the dynamin-related GTPase Mgm1p" Uncharacterized chr4:831931-832470 831931-832470 99.0% 121.65 71.12 95.45 65.50 56.14 44.92 96.38 80.47 50.53 0.36 0.33 0.21 -0.67 -0.68 Covered/w/another[1160]
YDR186C "Putative protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" Verified chr4:832856-835489 832856-835489 98.5% 153.75 309.05 149.90 139.50 182.27 191.13 231.40 144.70 186.70 0.85 0.59 0.77 0.37 0.99 Matched[1161]
YDR188W CCT6 "Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, essential protein that is required for the assembly of actin and tubulins in vivo; contains an ATP-binding motif" Verified chr4:836418-838058 836418-838058 98.3% 742.34 672.89 712.58 578.62 591.64 456.45 707.62 645.60 524.04 2.61 2.62 2.17 -0.30 0.09 Matched[1162]
YDR187C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified, essential ORF CCT6/YDR188W" Dubious chr4:836225-836743 836225-836743 97.9% 301.11 273.55 271.59 249.94 255.84 196.80 287.33 260.76 226.32 1.06 1.06 0.94 -0.20 0.07 Covered/w/another[1162]
YDR189W SLY1 Hydrophilic protein involved in vesicle trafficking between the ER and Golgi; SM (Sec1/Munc-18) family protein that binds the tSNARE Sed5p and stimulates its assembly into a trans-SNARE membrane-protein complex Verified chr4:838389-840389 838389-840389 98.9% 256.10 246.00 260.14 229.33 219.73 216.20 251.05 244.74 217.97 0.93 0.99 0.90 -0.17 0.36 Covered/w/another[1163]
YDR190C RVB1 Essential protein involved in transcription regulation; component of chromatin remodeling complexes; required for assembly and function of the INO80 complex; member of the RUVB-like protein family Verified chr4:840601-841992 840601-841992 99.3% 578.10 434.84 474.63 442.80 203.31 196.80 506.47 458.71 200.05 1.87 1.86 0.83 -1.20 -0.80 Covered/w/another[1163]
YDR191W HST4 "Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst3p in silencing at telomeres, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism" Verified chr4:842334-843446 842334-843446 98.8% 40.93 50.94 61.86 43.66 41.84 35.48 45.94 52.76 38.66 0.17 0.21 0.16 -0.45 0.16 Covered/w/another[1164]
YDR193W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:844551-844949 844551-844949 99.2% 32.86 42.97 42.97 30.33 48.03 25.28 37.91 36.65 36.65 0.14 0.15 0.15 0.00 -0.26 Covered/w/another[1164]
YDR192C NUP42 "Subunit of the nuclear pore complex (NPC) that localizes exclusively to the cytoplasmic side; involved in RNA export, most likely at a terminal step; interacts with Gle1p" Verified chr4:843566-844858 843566-844858 98.8% 64.20 68.90 72.03 56.37 66.55 51.67 66.55 64.20 59.11 0.25 0.26 0.24 -0.12 0.57 Covered/w/another[1164]
YDR194C MSS116 DEAD-box protein required for efficient splicing of mitochondrial Group I and II introns; non-polar RNA helicase that also facilities strand annealing Verified chr4:845949-847943 845949-847943 99.3% 588.85 480.27 512.09 476.74 341.90 239.88 534.56 494.41 290.89 1.97 2.01 1.21 -0.77 -0.99 Frag>80[1165,1166]
YDR194W-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr4:848068-848220 848068-848220 99.5% 6.57 0.00 0.00 0.00 0.00 0.00 3.29 0.00 0.00 0.01 0.00 0.00 NaN NaN
YDR195W REF2 "RNA-binding protein involved in the cleavage step of mRNA 3'-end formation prior to polyadenylation, and in snoRNA maturation; part of holo-CPF subcomplex APT, which associates with 3'-ends of snoRNA- and mRNA-encoding genes" Verified chr4:848596-850197 848596-850197 98.9% 116.13 87.73 91.51 43.55 125.59 65.64 101.93 67.53 95.62 0.38 0.27 0.40 0.50 0.72 Matched[1167]
YDR196C "Putative dephospho-CoA kinase (DPCK) that catalyzes the final step in Coenzyme A biosynthesis; essential for viability; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr4:850271-850996 850271-850996 99.5% 308.65 297.58 308.65 264.36 537.02 296.19 303.11 286.51 416.61 1.12 1.16 1.73 0.54 0.23 Matched[1168]
YDR197W CBS2 "Mitochondrial translational activator of the COB mRNA; interacts with translating ribosomes, acts on the COB mRNA 5'-untranslated leader" Verified chr4:851225-852394 851225-852394 98.9% 103.68 124.42 116.64 82.95 224.65 158.98 114.05 99.79 191.81 0.42 0.41 0.79 0.94 0.69 Matched[1169]
YDR198C RKM2 "Ribosomal protein lysine methyltransferase, responsible for epsilon-trimethylation of the lysine residue at position 10 of Rpl12Ap and Rpl12Bp" Verified chr4:852530-853969 852530-853969 99.2% 70.68 69.99 60.19 42.69 32.19 11.20 70.34 51.44 21.70 0.26 0.21 0.09 -1.25 -0.19 Matched[1170]
YDR199W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene VPS64; computationally predicted to have thiol-disulfide oxidoreductase activity" Dubious chr4:854172-854537 854172-854537 99.5% 159.32 200.53 167.56 109.88 381.82 217.01 179.92 138.72 299.42 0.66 0.56 1.24 1.11 -0.00 Covered/w/another[1171]
YDR200C VPS64 "Cytoplasmic protein required for cytoplasm to vacuole targeting of proteins; forms a complex with Far3p, Far7p, Far10p, and Far11p that is involved in pheromone-induced cell cycle arrest; also localized to the endoplasmic reticulum membrane" Verified chr4:854276-856090 854276-856090 99.2% 127.14 137.13 129.36 106.04 214.86 173.22 132.13 117.70 194.04 0.49 0.48 0.80 0.72 0.71 Matched[1171]
YDR201W SPC19 "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; also localized to nuclear side of spindle pole body" Verified chr4:856314-856811 856314-856811 98.3% 206.37 181.85 169.59 161.42 275.84 177.76 194.11 165.50 226.80 0.72 0.67 0.94 0.45 0.17 Matched[1172]
YDR203W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:857679-857996 857679-857996 99.4% 69.63 110.77 85.45 94.95 227.88 196.23 90.20 90.20 212.05 0.33 0.37 0.88 1.23 0.76 Matched[1173]
YDR202C RAV2 "Subunit of RAVE (Rav1p, Rav2p, Skp1p), a complex that associates with the V1 domain of the vacuolar membrane (H+)-ATPase (V-ATPase) and promotes assembly and reassembly of the holoenzyme" Verified chr4:856895-857950 856895-857950 99.2% 104.97 162.23 123.10 130.74 375.03 271.97 133.60 126.92 323.50 0.49 0.52 1.34 1.35 1.29 Matched[1173]
YDR204W COQ4 "Protein with a role in ubiquinone (Coenzyme Q) biosynthesis, possibly functioning in stabilization of Coq7p; located on the matrix face of the mitochondrial inner membrane; component of a mitochondrial ubiquinone-synthesizing complex" Verified chr4:858134-859141 858134-859141 98.4% 162.30 241.94 206.65 188.51 623.99 509.07 202.12 197.58 566.53 0.75 0.80 2.35 1.52 1.86 Matched[1174]
YDR205W MSC2 "Member of the cation diffusion facilitator family, localizes to the endoplasmic reticulum and nucleus; mutations affect the cellular distribution of zinc and also confer defects in meiotic recombination between homologous chromatids" Verified chr4:859343-861517 859343-861517 99.2% 72.78 75.56 71.85 60.72 54.70 37.55 74.17 66.29 46.12 0.27 0.27 0.19 -0.52 -0.07 Matched[1175]
YDR206W EBS1 "Cytoplasmic protein of unknown function, involved in inhibition of translation; interacts with cap binding protein Cdc33; contains an RNA recognition motif and similarity to Est1p; mRNA abundance regulated by mRNA decay factors" Verified chr4:862051-864705 862051-864705 98.9% 174.41 170.22 133.66 118.05 73.88 61.31 172.31 125.85 67.59 0.64 0.51 0.28 -0.90 -0.38 Matched[1176]
YDR207C UME6 "Key transcriptional regulator of early meiotic genes, binds URS1 upstream regulatory sequence, couples metabolic responses to nutritional cues with initiation and progression of meiosis, forms complex with Ime1p, and also with Sin3p-Rpd3p" Verified chr4:865009-867519 865009-867519 98.5% 147.92 165.70 126.50 124.48 128.52 122.05 156.81 125.49 125.29 0.58 0.51 0.52 -0.00 0.13 Matched[1177]
YDR208W MSS4 "Phosphatidylinositol-4-phosphate 5-kinase, involved in actin cytoskeleton organization and cell morphogenesis; multicopy suppressor of stt4 mutation" Verified chr4:868221-870560 868221-870560 98.9% 183.61 184.91 172.81 174.97 264.40 270.88 184.26 173.89 267.64 0.68 0.71 1.11 0.62 1.10 Matched[1178]
YDR210W Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery Uncharacterized chr4:871071-871298 871071-871298 96.9% 705.88 674.21 723.98 556.56 1248.87 660.63 690.05 640.27 954.75 2.55 2.60 3.96 0.58 0.55 Matched[1180]
YDR209C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps uncharacterized gene YDR210W." Dubious chr4:871033-871446 871033-871446 97.9% 697.90 675.71 638.72 547.47 1228.11 653.51 686.81 593.09 940.81 2.54 2.41 3.90 0.67 0.15 Matched[1180]
YDR211W GCD6 "Catalytic epsilon subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression" Verified chr4:884724-886862 884724-886862 98.8% 327.95 256.02 285.83 234.72 103.16 75.24 291.98 260.28 89.20 1.08 1.06 0.37 -1.54 -1.08 Matched[1182]
YDR212W TCP1 "Alpha subunit of chaperonin-containing T-complex, which mediates protein folding in the cytosol; involved in maintenance of actin cytoskeleton; homolog to Drosophila melanogaster and mouse tailless complex polypeptide" Verified chr4:887229-888908 887229-888908 98.8% 550.25 430.31 473.11 439.96 405.60 271.81 490.28 456.53 338.71 1.81 1.85 1.40 -0.43 -0.05 Matched[1183]
YDR213W UPC2 "Sterol regulatory element binding protein, induces transcription of sterol transport and biosynthetic genes; involved in the anaerobic induction of DAN/TIR mannoproteins and seripauperins; binucleate zinc cluster protein; Ecm22p homolog" Verified chr4:889748-892489 889748-892489 98.3% 60.85 112.05 39.33 37.47 40.07 53.80 86.45 38.40 46.93 0.32 0.16 0.19 0.29 0.77 Matched[1184]
YDR214W AHA1 Co-chaperone that binds to Hsp82p and activates its ATPase activity; similar to Hch1p; expression is regulated by stresses such as heat shock Verified chr4:892872-893924 892872-893924 98.5% 342.17 340.24 373.01 298.80 6861.69 4428.92 341.20 335.90 5645.30 1.26 1.36 23.39 4.07 3.18 Matched[1185]
YDR215C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; null mutant displays elevated sensitivity to expression of a mutant huntingtin fragment or of alpha-synuclein" Dubious chr4:894115-894498 894115-894498 97.9% 18.61 18.61 2.66 10.63 18.61 18.61 18.61 6.65 18.61 0.07 0.03 0.08 1.49 1.80 Frag<80[1186]
YDR216W ADR1 "Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization" Verified chr4:895031-899002 895031-899002 99.1% 42.19 32.53 96.83 98.61 103.69 163.42 37.36 97.72 133.55 0.14 0.40 0.55 0.45 1.17 Matched[1187]
YDR217C RAD9 "DNA damage-dependent checkpoint protein, required for cell-cycle arrest in G1/S, intra-S, and G2/M; transmits checkpoint signal by activating Rad53p and Chk1p; hyperphosphorylated by Mec1p and Tel1p; potential Cdc28p substrate" Verified chr4:899547-903476 899547-903476 99.3% 84.55 59.70 50.73 49.19 38.43 35.61 72.12 49.96 37.02 0.27 0.20 0.15 -0.43 -0.06 Frag>80[1188]
YDR218C SPR28 Sporulation-specific homolog of the yeast CDC3/10/11/12 family of bud neck microfilament genes; meiotic septin expressed at high levels during meiotic divisions and ascospore formation Verified chr4:903777-905048 903777-905048 99.4% 3.16 0.00 0.79 0.00 4.74 3.16 1.58 0.40 3.95 0.01 0.00 0.02 3.32 2.39
YDR219C MFB1 Mitochondria-associated F-box protein involved in maintenance of normal mitochondrial morphology; interacts with Skp1p through the F-box motif; preferentially localizes to the mother cell during budding Verified chr4:905451-906848 905451-906848 99.2% 131.89 133.33 115.32 121.80 209.01 176.58 132.61 118.56 192.79 0.49 0.48 0.80 0.70 0.77 Matched[1189]
YDR220C "Dubious open reading frame, null mutant exhibits synthetic phenotype with alpha-synuclein" Dubious chr4:906996-907289 906996-907289 98.7% 17.23 20.68 24.13 27.57 13.79 13.79 18.96 25.85 13.79 0.07 0.10 0.06 -0.91 0.71 Overlap[1189,1190]
YDR221W GTB1 "Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p, involved in removal of two glucose residues from N-linked glycans during glycoprotein biogenesis in the ER" Verified chr4:907326-909434 907326-909434 98.6% 116.91 99.59 87.08 109.69 87.56 95.26 108.25 98.39 91.41 0.40 0.40 0.38 -0.11 0.61 Matched[1190]
YDR222W Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern Uncharacterized chr4:910050-911297 910050-911297 98.9% 59.94 83.43 37.26 18.63 46.98 47.79 71.69 27.95 47.39 0.26 0.11 0.20 0.76 -0.24 Covered/w/another[1191]
YDR223W CRF1 "Transcriptional corepressor involved in the regulation of ribosomal protein gene transcription via the TOR signaling pathway and protein kinase A, phosphorylated by activated Yak1p which promotes accumulation of Crf1p in the nucleus" Verified chr4:912095-913498 912095-913498 98.6% 44.77 41.88 35.38 35.38 29.61 35.38 43.33 35.38 32.49 0.16 0.14 0.13 -0.12 0.63 Covered/w/another[1191]
YDR224C HTB1 "One of two nearly identical (see HTB2) histone H2B subtypes required for chromatin assembly and chromosome function; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation" Verified chr4:914313-914708 914313-914708 86.6% 6056.16 4763.83 5744.01 4425.43 4148.29 2855.96 5409.99 5084.72 3502.13 19.97 20.64 14.51 -0.54 -0.44 Matched[1192]
YDR225W HTA1 One of two nearly identical (see also HTA2) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p Verified chr4:915526-915924 915526-915924 71.2% 5808.04 4913.41 5212.80 3324.92 4476.67 1877.31 5360.73 4268.86 3176.99 19.79 17.33 13.16 -0.43 -1.85 Matched[1193]
YDR226W ADK1 "Adenylate kinase, required for purine metabolism; localized to the cytoplasm and the mitochondria; lacks cleavable signal sequence" Verified chr4:916482-917150 916482-917150 98.7% 3581.14 3276.65 3593.26 3185.76 1851.16 1633.02 3428.90 3389.51 1742.09 12.66 13.76 7.22 -0.96 -1.48 Matched[1194]
YDR227W SIR4 "Silent information regulator that, together with SIR2 and SIR3, is involved in assembly of silent chromatin domains at telomeres and the silent mating-type loci; potentially phosphorylated by Cdc28p; some alleles of SIR4 prolong lifespan" Verified chr4:917567-921643 917567-921643 98.7% 100.40 91.95 71.57 74.55 50.70 63.12 96.17 73.06 56.91 0.36 0.30 0.24 -0.36 0.07 Covered/w/another[1195]
YDR228C PCF11 "mRNA 3' end processing factor, essential component of cleavage and polyadenylation factor IA (CF IA), involved in pre-mRNA 3' end processing and in transcription termination; binds C-terminal domain of largest subunit of RNA pol II (Rpo21p)" Verified chr4:921922-923802 921922-923802 98.4% 119.91 125.85 98.85 65.90 102.63 64.28 122.88 82.37 83.45 0.45 0.33 0.35 0.02 0.39 Covered/w/another[1195]
YDR229W IVY1 "Phospholipid-binding protein that interacts with both Ypt7p and Vps33p, may partially counteract the action of Vps33p and vice versa, localizes to the rim of the vacuole as cells approach stationary phase" Verified chr4:924781-926142 924781-926142 98.4% 135.10 132.11 132.86 134.35 197.80 161.97 133.61 133.61 179.88 0.49 0.54 0.75 0.43 0.84 Matched[1197]
YDR230W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene COX20" Dubious chr4:926219-926566 926219-926566 99.0% 156.75 296.08 267.05 296.08 627.00 310.60 226.42 281.57 468.80 0.84 1.14 1.94 0.74 0.05 Covered/w/another[1197]
YDR231C COX20 "Mitochondrial inner membrane protein, required for proteolytic processing of Cox2p and its assembly into cytochrome c oxidase" Verified chr4:926289-926906 926289-926906 98.8% 171.88 266.83 258.65 278.29 538.57 322.49 219.36 268.47 430.53 0.81 1.09 1.78 0.68 0.59 Covered/w/another[1197]
YDR232W HEM1 "5-aminolevulinate synthase, catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p" Verified chr4:927448-929094 927448-929094 98.7% 506.53 573.00 492.99 418.52 238.80 242.49 539.76 455.75 240.65 1.99 1.85 1.00 -0.92 -0.68 Matched[1198]
YDR233C RTN1 ER membrane protein that interacts with exocyst subunit Sec6p and with Yip3p; also interacts with Sbh1p; null mutant has an altered (mostly cisternal) ER morphology; member of the RTNLA (reticulon-like A) subfamily Verified chr4:929466-930353 929466-930353 98.5% 1877.89 1749.88 1752.17 1457.28 1010.38 694.92 1813.89 1604.72 852.65 6.70 6.51 3.53 -0.91 -0.67 Frag>80[1199,1200]
YDR234W LYS4 "Homoaconitase, catalyzes the conversion of homocitrate to homoisocitrate, which is a step in the lysine biosynthesis pathway" Verified chr4:931125-933206 931125-933206 98.6% 223.63 208.53 187.58 142.75 26.31 18.03 216.08 165.16 22.17 0.80 0.67 0.09 -2.90 -2.16 Matched[1201]
YDR235W PRP42 "U1 snRNP protein involved in splicing, required for U1 snRNP biogenesis; contains multiple tetriatricopeptide repeats" Verified chr4:933500-935134 933500-935134 99.0% 115.50 151.95 100.06 108.09 111.80 74.74 133.72 104.08 93.27 0.49 0.42 0.39 -0.16 -0.34 Covered/w/another[1202]
YDR236C FMN1 "Riboflavin kinase, phosphorylates riboflavin to form riboflavin monophosphate (FMN), which is a necessary cofactor for many enzymes; localizes to microsomes and to the mitochondrial inner membrane" Verified chr4:935232-935888 935232-935888 99.1% 165.81 158.14 173.49 162.74 290.17 214.94 161.98 168.12 252.56 0.60 0.68 1.05 0.59 0.16 Covered/w/another[1202]
YDR237W MRPL7 Mitochondrial ribosomal protein of the large subunit Verified chr4:936611-937489 936611-937489 98.8% 240.61 204.92 272.85 249.82 340.77 195.71 222.77 261.33 268.24 0.82 1.06 1.11 0.04 0.06 Covered/w/another[1202]
YDR238C SEC26 "Essential beta-coat protein of the COPI coatomer, involved in ER-to-Golgi protein trafficking and maintenance of normal ER morphology; shares 43% sequence identity with mammalian beta-coat protein (beta-COP)" Verified chr4:937891-940812 937891-940812 99.1% 667.77 595.22 612.84 589.70 415.59 526.13 631.50 601.27 470.86 2.33 2.44 1.95 -0.35 0.28 Matched[1203]
YDR239C "Protein of unknown function that may interact with ribosomes, based on co-purification experiments" Verified chr4:941053-943416 941053-943416 99.1% 61.05 50.80 40.98 32.02 38.00 29.46 55.93 36.50 33.73 0.21 0.15 0.14 -0.11 0.15 Matched[1204]
YDR241W BUD26 "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 1% of ORF overlaps the verified gene SNU56; diploid mutant displays a weak budding pattern phenotype in a systematic assay" Dubious chr4:945147-945434 945147-945434 89.2% 31.13 27.24 19.46 31.13 42.80 23.35 29.18 25.29 33.07 0.11 0.10 0.14 0.39 -0.06 Frag<80[1206]
YDR240C SNU56 "Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counterpart; interacts with mRNA in commitment complex" Verified chr4:943670-945148 943670-945148 99.2% 70.86 59.28 59.28 59.28 23.85 26.57 65.07 59.28 25.21 0.24 0.24 0.10 -1.23 -0.42 Matched[1205]
YDR242W AMD2 Putative amidase Verified chr4:946803-948452 946803-948452 98.8% 79.10 88.92 66.84 38.02 66.23 55.19 84.01 52.43 60.71 0.31 0.21 0.25 0.21 0.41 Covered/w/another[1207]
YDR243C PRP28 "RNA helicase in the DEAD-box family, involved in RNA isomerization at the 5' splice site" Verified chr4:948514-950280 948514-950280 99.3% 66.71 50.18 50.18 34.21 37.63 23.95 58.44 42.19 30.79 0.22 0.17 0.13 -0.45 -0.20 Covered/w/another[1207]
YDR244W PEX5 "Peroxisomal membrane signal receptor for the C-terminal tripeptide signal sequence (PTS1) of peroxisomal matrix proteins, required for peroxisomal matrix protein import; also proposed to have PTS1-receptor independent functions" Verified chr4:950559-952397 950559-952397 98.5% 96.57 105.40 98.78 94.92 156.72 109.26 100.99 96.85 132.99 0.37 0.39 0.55 0.46 0.82 Matched[1208]
YDR245W MNN10 "Subunit of a Golgi mannosyltransferase complex also containing Anp1p, Mnn9p, Mnn11p, and Hoc1p that mediates elongation of the polysaccharide mannan backbone; membrane protein of the mannosyltransferase family" Verified chr4:952796-953977 952796-953977 98.5% 491.34 402.00 426.91 394.27 210.45 163.21 446.67 410.59 186.83 1.65 1.67 0.77 -1.14 -1.00 Matched[1209]
YDR246W TRS23 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic; human homolog is TRAPPC4 Verified chr4:954284-954943 954284-954943 98.6% 170.63 139.88 127.59 149.11 285.92 247.49 155.26 138.35 266.70 0.57 0.56 1.11 0.95 1.07 Covered/w/another[1210]
YDR246W-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr4:955129-955329 955129-955329 98.6% 10.09 25.23 20.19 20.19 25.23 20.19 17.66 20.19 22.71 0.07 0.08 0.09 0.17 NaN Covered/w/another[1210]
YDR247W VHS1 "Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; homolog of Sks1p" Verified chr4:956009-957394 956009-957394 98.9% 123.34 137.93 118.23 125.52 240.83 198.50 130.63 121.88 219.67 0.48 0.49 0.91 0.85 1.14 Covered/w/another[1210]
YDR248C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr4:957754-958335 957754-958335 99.3% 273.32 375.38 280.24 249.10 887.42 501.66 324.35 264.67 694.54 1.20 1.07 2.88 1.39 0.75 Covered/w/another[1210]
YDR249C Putative protein of unknown function Uncharacterized chr4:958677-959798 958677-959798 99.1% 53.08 55.77 46.78 29.69 53.98 34.18 54.42 38.23 44.08 0.20 0.16 0.18 0.21 0.04 Matched[1211]
YDR250C "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data" Dubious chr4:960082-960357 960082-960357 98.5% 18.40 22.08 11.04 11.04 11.04 36.79 20.24 11.04 23.92 0.07 0.04 0.10 1.12 0.47 Overlap[1212]
YDR251W PAM1 "Essential protein of unknown function; exhibits variable expression during colony morphogenesis; overexpression permits survival without protein phosphatase 2A, inhibits growth, and induces a filamentous phenotype" Verified chr4:960610-963102 960610-963102 98.9% 272.64 292.52 307.53 301.45 339.18 281.97 282.58 304.49 310.57 1.04 1.24 1.29 0.03 0.44 Matched[1212]
YDR252W BTT1 "Beta3 subunit of the heterotrimeric nascent polypeptide-associated complex (alpha, beta1, beta3) which binds ribosomes via its beta-subunits in close proximity to nascent polypeptides" Verified chr4:963408-963857 963408-963857 98.6% 76.63 74.38 78.89 58.60 112.70 51.84 75.51 68.75 82.27 0.28 0.28 0.34 0.26 0.45 Covered/w/another[1213]
YDR253C MET32 "Zinc-finger DNA-binding protein, involved in transcriptional regulation of the methionine biosynthetic genes, similar to Met31p" Verified chr4:963986-964561 963986-964561 99.5% 68.05 111.67 122.14 54.09 92.48 33.15 89.86 88.11 62.81 0.33 0.36 0.26 -0.49 -0.56 Matched[1213]
YDR254W CHL4 "Outer kinetochore protein required for chromosome stability, interacts with kinetochore proteins Ctf19p, Ctf3p, and Iml3p; exhibits a two-hybrid interaction with Mif2p; association with CEN DNA requires Ctf19p" Verified chr4:965109-966485 965109-966485 98.9% 140.31 196.88 145.45 91.09 194.67 118.27 168.60 118.27 156.47 0.62 0.48 0.65 0.40 -0.63 Matched[1214]
YDR255C RMD5 "Cytosolic protein required for sporulation; also required for the ubiquitination of the gluconeogenetic enzyme fructose-1,6-bisphosphatase, which is degraded rapidly after the switch from gluconeogenesis to glycolysis" Verified chr4:966553-967818 966553-967818 99.2% 99.50 142.48 121.78 97.90 176.70 145.66 120.99 109.84 161.18 0.45 0.45 0.67 0.55 0.62 Frag<80[1215]
YDR256C CTA1 "Catalase A, breaks down hydrogen peroxide in the peroxisomal matrix formed by acyl-CoA oxidase (Pox1p) during fatty acid beta-oxidation" Verified chr4:968129-969676 968129-969676 98.9% 54.88 62.06 42.46 31.36 53.57 35.93 58.47 36.91 44.75 0.22 0.15 0.19 0.28 1.66 Matched[1216]
YDR257C SET7 "Nuclear protein that contains a SET-domain, which have been shown to mediate methyltransferase activity in other proteins" Verified chr4:969986-971470 969986-971470 99.4% 136.88 116.55 125.36 124.00 91.48 43.37 126.72 124.68 67.42 0.47 0.51 0.28 -0.89 -0.81 Matched[1217]
YDR258C HSP78 Oligomeric mitochondrial matrix chaperone that cooperates with Ssc1p in mitochondrial thermotolerance after heat shock; prevents the aggregation of misfolded matrix proteins; component of the mitochondrial proteolysis system Verified chr4:971804-974239 971804-974239 99.2% 167.15 396.37 230.04 328.93 9184.69 7548.74 281.76 279.48 8366.71 1.04 1.13 34.67 4.90 4.45 Frag>80[1218,1219]
YDR259C YAP6 Putative basic leucine zipper (bZIP) transcription factor; overexpression increases sodium and lithium tolerance Verified chr4:974627-975778 974627-975778 99.0% 42.95 64.87 40.32 43.83 140.25 74.51 53.91 42.08 107.38 0.20 0.17 0.44 1.35 1.16 Matched[1220]
YDR260C SWM1 "Subunit of the anaphase-promoting complex, which is an E3 ubiquitin ligase that regulates the metaphase-anaphase transition and exit from mitosis; required for activation of the daughter-specific gene expression and spore wall maturation" Verified chr4:976713-977225 976713-977225 99.1% 131.80 116.07 125.90 98.36 159.34 45.25 123.93 112.13 102.30 0.46 0.46 0.42 -0.13 -0.92 Matched[1221]
YDR261C EXG2 "Exo-1,3-beta-glucanase, involved in cell wall beta-glucan assembly; may be anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor" Verified chr4:977517-979205 977517-979205 99.1% 198.40 276.68 170.31 129.08 211.54 178.68 237.54 149.69 195.11 0.88 0.61 0.81 0.38 1.09 Matched[1222]
YDR262W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole and is induced in response to the DNA-damaging agent MMS; gene expression increases in response to Zymoliase treatment Uncharacterized chr4:993130-993948 993130-993948 98.6% 314.70 365.49 271.33 236.64 478.24 344.43 340.10 253.99 411.34 1.26 1.03 1.70 0.70 0.86 Matched[1226]
YDR263C DIN7 "Mitochondrial nuclease functioning in DNA repair and replication, modulates the stability of the mitochondrial genome, induced by exposure to mutagens, also induced during meiosis at a time nearly coincident with commitment to recombination" Verified chr4:994238-995530 994238-995530 99.3% 56.07 50.62 40.50 30.37 64.64 44.39 53.35 35.43 54.51 0.20 0.14 0.23 0.62 1.03 Matched[1227]
YDR264C AKR1 Palmitoyl transferase involved in protein palmitoylation; acts as a negative regulator of pheromone response pathway; required for endocytosis of pheromone receptors; involved in cell shape control; contains ankyrin repeats Verified chr4:996025-998319 996025-998319 99.0% 261.93 206.46 224.95 218.35 254.45 208.22 234.20 221.65 231.34 0.86 0.90 0.96 0.06 0.45 Matched[1228]
YDR265W PEX10 "C3HC4-type RING-finger peroxisomal membrane peroxin required for peroxisomal matrix protein import, interacts with Pex12p, links ubiquitin-conjugating Pex4p to import machinery; mutations in human homolog cause various peroxisomal disorders" Verified chr4:998860-999873 998860-999873 98.8% 114.81 114.81 99.84 72.88 131.79 85.86 114.81 86.36 108.82 0.42 0.35 0.45 0.33 0.08 Matched[1229]
YDR266C "Protein of unknown function that may interact with ribosomes, based on co-purification experiments;green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; contains a RING finger domain" Verified chr4:1000100-1002019 1000100-1002019 98.9% 268.02 235.90 221.69 223.79 194.83 230.11 251.96 222.74 212.47 0.93 0.90 0.88 -0.07 0.44 Covered/w/another[1230]
YDR267C CIA1 Essential protein involved in assembly of cytosolic and nuclear iron-sulfur proteins Verified chr4:1002506-1003498 1002506-1003498 99.3% 174.35 154.07 157.11 136.84 72.98 52.71 164.21 146.98 62.85 0.61 0.60 0.26 -1.23 -1.35 Covered/w/another[1230]
YDR268W MSW1 Mitochondrial tryptophanyl-tRNA synthetase Verified chr4:1004000-1005139 1004000-1005139 98.6% 110.27 106.71 115.60 112.05 119.16 85.37 108.49 113.82 102.26 0.40 0.46 0.42 -0.15 0.20 Frag>80[1231,1232]
YDR270W CCC2 "Cu(+2)-transporting P-type ATPase, required for export of copper from the cytosol into an extracytosolic compartment; has similarity to human proteins involved in Menkes and Wilsons diseases" Verified chr4:1005671-1008685 1005671-1008685 98.7% 60.13 46.02 52.40 45.01 81.96 66.51 53.07 48.71 74.24 0.20 0.20 0.31 0.61 1.07 Matched[1233]
YDR269C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:1005661-1005984 1005661-1005984 98.4% 25.08 18.81 34.49 25.08 31.36 62.71 21.95 29.79 47.03 0.08 0.12 0.19 0.66 -0.00 Covered/w/another[1233]
YDR271C Hypothetical protein Dubious chr4:1008391-1008762 1008391-1008762 98.9% 84.27 92.42 92.42 54.37 157.66 97.86 88.35 73.39 127.76 0.33 0.30 0.53 0.80 1.08 Covered/w/another[1233]
YDR272W GLO2 "Cytoplasmic glyoxalase II, catalyzes the hydrolysis of S-D-lactoylglutathione into glutathione and D-lactate" Verified chr4:1009006-1009830 1009006-1009830 98.4% 347.24 440.82 449.44 403.88 1336.00 959.21 394.03 426.66 1147.61 1.45 1.73 4.75 1.43 1.21 Matched[1234]
YDR273W DON1 "Meiosis-specific component of the spindle pole body, part of the leading edge protein (LEP) coat, forms a ring-like structure at the leading edge of the prospore membrane during meiosis II" Verified chr4:1010172-1011269 1010172-1011269 98.4% 34.24 72.18 34.24 14.81 37.94 26.84 53.21 24.52 32.39 0.20 0.10 0.13 0.40 0.71 Covered/w/another[1235]
YDR274C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:1011585-1011956 1011585-1011956 97.6% 27.54 338.73 44.06 44.06 35.80 46.82 183.13 44.06 41.31 0.68 0.18 0.17 -0.09 0.32 Covered/w/another[1235]
YDR275W BSC2 "Protein of unknown function, ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression" Verified chr4:1012248-1012955 1012248-1012955 98.8% 190.20 474.79 214.52 153.02 403.29 238.83 332.50 183.77 321.06 1.23 0.75 1.33 0.80 0.23 Matched[1236]
YDR276C PMP3 "Small plasma membrane protein related to a family of plant polypeptides that are overexpressed under high salt concentration or low temperature, not essential for viability, deletion causes hyperpolarization of the plasma membrane potential" Verified chr4:1013472-1013639 1013472-1013639 98.6% 3785.66 4383.40 4371.32 4093.58 8507.17 4818.11 4084.53 4232.45 6662.64 15.08 17.18 27.61 0.65 -0.79 Matched[1237]
YDR277C MTH1 "Negative regulator of the glucose-sensing signal transduction pathway, required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation" Verified chr4:1014397-1015698 1014397-1015698 99.1% 179.79 307.66 214.67 259.61 99.97 65.10 243.73 237.14 82.53 0.90 0.96 0.34 -1.52 -1.46 Matched[1239]
YDR278C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:1016997-1017314 1016997-1017314 83.5% 0.00 3.77 0.00 0.00 3.77 7.54 1.88 0.00 5.65 0.01 0.00 0.02 Inf -0.24
YDR279W RNH202 "Ribonuclease H2 subunit, required for RNase H2 activity" Verified chr4:1019364-1020416 1019364-1020416 99.0% 172.72 127.62 134.34 143.94 96.92 50.86 150.17 139.14 73.89 0.55 0.56 0.31 -0.91 -0.98 Matched[1240]
YDR280W RRP45 Protein involved in rRNA processing; component of the exosome 3->5 exonuclease complex Verified chr4:1020743-1021660 1020743-1021660 98.6% 255.23 204.40 239.76 192.25 135.90 85.08 229.81 216.00 110.49 0.85 0.88 0.46 -0.97 -1.00 Matched[1241]
YDR281C PHM6 "Protein of unknown function, expression is regulated by phosphate levels" Verified chr4:1022003-1022317 1022003-1022317 99.0% 307.69 314.10 291.67 115.38 25.64 3.21 310.90 203.53 14.42 1.15 0.83 0.06 -3.82 -3.44 Matched[1242]
YDR282C Putative protein of unknown function Uncharacterized chr4:1023507-1024751 1023507-1024751 99.4% 49.32 50.93 52.55 32.34 105.91 58.21 50.12 42.44 82.06 0.19 0.17 0.34 0.95 0.79 Matched[1243]
YDR283C GCN2 "Protein kinase, phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex" Verified chr4:1025066-1030045 1025066-1030045 99.3% 104.54 98.48 81.29 76.84 49.95 43.68 101.51 79.06 46.81 0.37 0.32 0.19 -0.76 -0.40 Matched[1244]
YDR284C DPP1 "Diacylglycerol pyrophosphate (DGPP) phosphatase, zinc-regulated vacuolar membrane-associated lipid phosphatase, dephosphorylates DGPP to phosphatidate (PA) and Pi, then PA to diacylglycerol; involved in lipid signaling and cell metabolism" Verified chr4:1030546-1031415 1030546-1031415 98.9% 489.39 506.83 513.80 481.26 419.65 212.73 498.11 497.53 316.19 1.84 2.02 1.31 -0.65 -0.95 Frag>80[1245,1246]
YDR285W ZIP1 Transverse filament protein of the synaptonemal complex; required for normal levels of meiotic recombination and pairing between homologous chromosome during meiosis; potential Cdc28p substrate Verified chr4:1032432-1035059 1032432-1035059 98.7% 30.09 35.87 27.77 23.53 45.13 25.84 32.98 25.65 35.49 0.12 0.10 0.15 0.47 0.67 Frag>80[1247]
YDR286C Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site Uncharacterized chr4:1035227-1035571 1035227-1035571 99.2% 110.99 148.96 105.15 93.46 283.32 108.07 129.97 99.31 195.69 0.48 0.40 0.81 0.98 0.47 Matched[1248]
YDR287W Inositol monophosphatase Uncharacterized chr4:1035991-1036869 1035991-1036869 98.4% 145.61 166.41 108.63 128.27 307.40 228.81 156.01 118.45 268.10 0.58 0.48 1.11 1.18 0.94 Frag>80[1249,1250]
YDR288W NSE3 Essential subunit of the Mms21-Smc5-Smc6 complex; protein of unknown function; required for DNA repair and growth Verified chr4:1037191-1038102 1037191-1038102 98.7% 131.09 141.09 132.20 123.32 255.52 105.54 136.09 127.76 180.53 0.50 0.52 0.75 0.50 0.35 Covered/w/another[1251]
YDR290W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF RTT103" Dubious chr4:1039366-1039695 1039366-1039695 98.9% 36.75 55.13 70.44 42.88 49.00 45.94 45.94 56.66 47.47 0.17 0.23 0.20 -0.26 0.05 Overlap[1251]
YDR289C RTT103 "Protein that interacts with exonuclease Rat1p and Rai1p and plays a role in transcription termination by RNA polymerase II, has an RPR domain (carboxy-terminal domain interacting domain); also involved in regulation of Ty1 transposition" Verified chr4:1038276-1039505 1038276-1039505 97.9% 126.23 133.70 158.62 141.18 204.29 115.43 129.97 149.90 159.86 0.48 0.61 0.66 0.09 0.11 Covered/w/another[1251]
YDR291W Putative DNA helicase Uncharacterized chr4:1039724-1042957 1039724-1042957 98.7% 73.92 79.24 61.08 57.00 49.80 44.48 76.58 59.04 47.14 0.28 0.24 0.20 -0.32 0.10 Matched[1252]
YDR292C SRP101 Signal recognition particle (SRP) receptor - alpha subunit; contain GTPase domains; involved in SRP-dependent protein targeting; interacts with SRP102p Verified chr4:1043142-1045007 1043142-1045007 99.3% 219.73 204.61 207.31 235.92 153.32 112.29 212.17 221.62 132.81 0.78 0.90 0.55 -0.74 -0.71 Matched[1253]
YDR293C SSD1 "Protein with a role in maintenance of cellular integrity, interacts with components of the TOR pathway; ssd1 mutant of a clinical S. cerevisiae strain displays elevated virulence" Verified chr4:1045636-1049388 1045636-1049388 99.0% 296.93 363.16 314.70 280.51 296.93 491.83 330.04 297.60 394.38 1.22 1.21 1.63 0.41 1.45 Covered[1254]
YDR294C DPL1 "Dihydrosphingosine phosphate lyase, regulates intracellular levels of sphingolipid long-chain base phosphates (LCBPs), degrades phosphorylated long chain bases, prefers C16 dihydrosphingosine-l-phosphate as a substrate" Verified chr4:1050455-1052224 1050455-1052224 99.0% 279.02 304.13 268.18 234.52 292.72 269.89 291.58 251.35 281.31 1.08 1.02 1.17 0.16 0.84 Frag>80[1255,1256]
YDR295C HDA2 Subunit of a possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex containing an Hda1p homodimer and an Hda2p-Hda3p heterodimer; involved in telomere maintenance Verified chr4:1052619-1054643 1052619-1054643 99.2% 100.58 94.11 78.17 63.73 126.97 109.05 97.34 70.95 118.01 0.36 0.29 0.49 0.73 1.17 Matched[1257]
YDR296W MHR1 Protein involved in homologous recombination in mitochondria and in transcription regulation in nucleus; binds to activation domains of acidic activators; required for recombination-dependent mtDNA partitioning Verified chr4:1055208-1055888 1055208-1055888 98.1% 348.69 341.21 330.74 348.69 419.03 309.78 344.95 339.71 364.41 1.27 1.38 1.51 0.10 0.37 Matched[1258]
YDR297W SUR2 "Sphinganine C4-hydroxylase, catalyses the conversion of sphinganine to phytosphingosine in sphingolipid biosyntheis" Verified chr4:1056547-1057596 1056547-1057596 98.9% 564.55 1237.96 666.67 758.19 210.02 178.23 901.25 712.43 194.12 3.33 2.89 0.80 -1.88 -1.48 Matched[1259]
YDR298C ATP5 "Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase, which is an evolutionarily conserved enzyme complex required for ATP synthesis; homologous to bovine subunit OSCP (oligomycin sensitivity-conferring protein); phosphorylated" Verified chr4:1058172-1058810 1058172-1058810 99.1% 750.10 799.05 876.43 1046.98 824.32 604.82 774.58 961.71 714.57 2.86 3.90 2.96 -0.43 -0.41 Matched[1261]
YDR299W BFR2 Essential protein possibly involved in secretion; multicopy suppressor of sensitivity to Brefeldin A Verified chr4:1059623-1061227 1059623-1061227 98.1% 209.62 142.92 127.04 111.16 11.43 7.62 176.27 119.10 9.53 0.65 0.48 0.04 -3.64 -3.43 Matched[1262]
YDR300C PRO1 "Gamma-glutamyl kinase, catalyzes the first step in proline biosynthesis" Verified chr4:1061501-1062787 1061501-1062787 99.2% 256.05 198.11 204.37 173.83 31.32 12.53 227.08 189.10 21.92 0.84 0.77 0.09 -3.11 -2.81 Matched[1263]
YDR301W CFT1 "RNA-binding subunit of the mRNA cleavage and polyadenylation factor; involved in poly(A) site recognition and required for both pre-mRNA cleavage and polyadenylation, 51% sequence similarity with mammalian AAUAA-binding subunit of CPSF" Verified chr4:1063348-1067421 1063348-1067421 98.9% 89.12 96.31 70.50 75.21 41.21 65.29 92.72 72.86 53.25 0.34 0.30 0.22 -0.45 0.14 Matched[1264]
YDR302W GPI11 ER membrane protein involved in a late step of glycosylphosphatidylinositol (GPI) anchor assembly; involved in the addition of phosphoethanolamine to the multiply mannosylated GPI intermediate; human PIG-Fp is a functional homolog Verified chr4:1067727-1068386 1067727-1068386 99.1% 315.04 195.76 275.28 250.81 295.16 136.11 255.40 263.05 215.64 0.94 1.07 0.89 -0.29 -0.85 Matched[1265]
YDR303C RSC3 Component of the RSC chromatin remodeling complex; essential gene required for maintenance of proper ploidy and regulation of ribosomal protein genes and the cell wall/stress response; highly similar to Rsc30p Verified chr4:1068725-1071382 1068725-1071382 99.1% 155.21 142.31 135.86 130.93 165.84 117.26 148.76 133.39 141.55 0.55 0.54 0.59 0.09 0.13 Matched[1266]
YDR304C CPR5 "Peptidyl-prolyl cis-trans isomerase (cyclophilin) of the endoplasmic reticulum, catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; transcriptionally induced in response to unfolded proteins in the ER" Verified chr4:1071876-1072553 1071876-1072553 96.9% 1184.47 1559.00 1350.42 1432.63 1816.29 1621.42 1371.73 1391.52 1718.85 5.06 5.65 7.12 0.30 0.33 Matched[1267]
YDR305C HNT2 Dinucleoside triphosphate hydrolase; has similarity to the tumor suppressor FHIT and belongs to the histidine triad (HIT) superfamily of nucleotide-binding proteins Verified chr4:1072742-1073484 1072742-1073308,1073398-1073484 99.1% 188.26 158.94 141.97 118.82 205.23 77.16 173.60 130.39 141.19 0.64 0.53 0.59 0.11 -0.08 Covered/w/another[1268]
YDR306C F-box protein of unknown function; interacts with Sgt1p via a Leucine-Rich Repeat (LRR) domain Uncharacterized chr4:1073731-1075167 1073731-1075167 99.1% 115.87 158.00 138.34 138.34 256.31 212.07 136.93 138.34 234.19 0.51 0.56 0.97 0.76 1.06 Covered/w/another[1268]
YDR307W Putative protein of unknown function Uncharacterized chr4:1075861-1077849 1075861-1077849 99.1% 137.50 147.14 134.96 112.64 203.45 128.36 142.32 123.80 165.91 0.53 0.50 0.69 0.42 0.23 Matched[1269]
YDR308C SRB7 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; target of the global repressor Tup1p Verified chr4:1078023-1078445 1078023-1078445 99.4% 187.82 185.44 166.42 164.04 223.48 145.02 186.63 165.23 184.25 0.69 0.67 0.76 0.16 -0.36 Covered/w/another[1269]
YDR309C GIC2 "Protein of unknown function involved in initiation of budding and cellular polarization, interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain" Verified chr4:1079044-1080195 1079044-1080195 98.6% 472.75 398.80 427.85 352.14 210.40 198.96 435.77 389.99 204.68 1.61 1.58 0.85 -0.93 -0.56 Matched[1271]
YDR310C SUM1 "Transcriptional repressor required for mitotic repression of middle sporulation-specific genes; involved in telomere maintenance, regulated by the pachytene checkpoint" Verified chr4:1081124-1084312 1081124-1084312 99.0% 231.30 202.79 197.40 165.40 152.72 204.69 217.04 181.40 178.70 0.80 0.74 0.74 -0.02 0.41 Frag>80[1272,1273,1274]
YDR311W TFB1 "Subunit of TFIIH and nucleotide excision repair factor 3 complexes, required for nucleotide excision repair, target for transcriptional activators" Verified chr4:1085062-1086990 1085062-1086990 98.7% 116.57 106.59 87.69 89.79 99.77 72.46 111.58 88.74 86.11 0.41 0.36 0.36 -0.04 0.29 Matched[1275]
YDR312W SSF2 "Protein required for ribosomal large subunit maturation, functionally redundant with Ssf1p; member of the Brix family" Verified chr4:1087578-1088939 1087578-1088939 59.3% 139.83 110.13 113.84 69.30 17.32 11.14 124.98 91.57 14.23 0.46 0.37 0.06 -2.69 -2.26 Frag>80[1276,1277,1278]
YDR313C PIB1 "RING-type ubiquitin ligase of the endosomal and vacuolar membranes, binds phosphatidylinositol(3)-phosphate; contains a FYVE finger domain" Verified chr4:1089216-1090076 1089216-1090076 99.1% 132.47 106.68 109.03 132.47 345.84 302.46 119.58 120.75 324.15 0.44 0.49 1.34 1.42 1.50 Matched[1279]
YDR314C RAD34 Protein involved in nucleotide excision repair (NER); homologous to RAD4 Verified chr4:1090430-1092508 1090430-1092508 99.3% 26.15 32.44 26.15 24.21 42.61 46.97 29.29 25.18 44.79 0.11 0.10 0.19 0.83 1.60 Matched[1280]
YDR315C IPK1 "Inositol 1,3,4,5,6-pentakisphosphate 2-kinase, nuclear protein required for synthesis of 1,2,3,4,5,6-hexakisphosphate (phytate), which is integral to cell function; has 2 motifs conserved in other fungi; ipk1 gle1 double mutant is inviable" Verified chr4:1092738-1093583 1092738-1093583 99.3% 110.67 121.38 85.68 88.06 107.10 67.83 116.03 86.87 87.47 0.43 0.35 0.36 0.01 -0.45 Covered/w/another[1281]
YDR316W OMS1 Protein integral to the mitochondrial membrane; has a conserved methyltransferase motif; multicopy suppressor of respiratory defects caused by OXA1 mutations Verified chr4:1093760-1095175 1093760-1095175 98.5% 150.54 134.05 139.79 146.24 169.18 116.85 142.30 143.02 143.02 0.53 0.58 0.59 0.00 0.16 Frag<80[1282,1283]
YDR317W HIM1 Protein of unknown function involved in DNA repair Verified chr4:1102181-1103425 1102181-1103425 98.7% 47.18 39.86 47.99 36.60 32.54 23.59 43.52 42.30 28.06 0.16 0.17 0.12 -0.59 -0.03 Covered[1284]
YDR318W MCM21 "Protein involved in minichromosome maintenance; component of the COMA complex (Ctf19p, Okp1p, Mcm21p, Ame1p) that bridges kinetochore subunits that are in contact with centromeric DNA and the subunits bound to microtubules" Verified chr4:1103755-1104944 1103755-1103806,1103890-1104944 98.8% 134.46 128.06 110.68 111.59 118.91 81.41 131.26 111.14 100.16 0.48 0.45 0.41 -0.15 -0.24
YDR319C Putative protein of unknown function; identified as interacting with Sst2p and Hsp82p in high-throughput two-hybrid screens Uncharacterized chr4:1105000-1105824 1105000-1105824 99.0% 155.48 145.68 154.25 175.07 340.34 221.59 150.58 164.66 280.96 0.56 0.67 1.16 0.77 0.42 Covered/w/another[1285]
YDR320C SWA2 Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles Verified chr4:1106092-1108098 1106092-1108098 99.0% 79.51 76.99 70.45 80.01 110.70 129.32 78.25 75.23 120.01 0.29 0.31 0.50 0.67 1.01 Covered/w/another[1285]
YDR320W-B "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene DAD4/YDR320C-A" Dubious chr4:1108481-1108618 1108481-1108618 98.9% 102.56 73.26 146.52 65.93 212.45 168.50 87.91 106.23 190.48 0.32 0.43 0.79 0.84 NaN Matched[1286]
YDR320C-A DAD4 "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis" Verified chr4:1108277-1108495 1108277-1108495 99.4% 408.96 385.99 496.27 372.20 634.12 358.41 397.47 434.23 496.27 1.47 1.76 2.06 0.19 -0.54 Matched[1286]
YDR321W ASP1 "Cytosolic L-asparaginase, involved in asparagine catabolism" Verified chr4:1108699-1109844 1108699-1109844 98.9% 587.56 392.59 495.81 441.11 149.10 125.28 490.08 468.46 137.19 1.81 1.90 0.57 -1.77 -0.97 Matched[1287]
YDR322W MRPL35 Mitochondrial ribosomal protein of the large subunit Verified chr4:1110586-1111689 1110586-1111689 98.9% 176.83 167.67 208.89 207.06 168.58 137.43 172.25 207.98 153.01 0.64 0.84 0.63 -0.44 -0.14 Matched[1288]
YDR322C-A TIM11 "Subunit e of mitochondrial F1F0-ATPase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; essential for the dimeric and oligomeric state of ATP synthase" Verified chr4:1112000-1112290 1112000-1112290 99.3% 709.55 733.78 917.22 830.69 1453.71 937.99 721.66 873.95 1195.85 2.66 3.55 4.95 0.45 -0.29 Matched[1289]
YDR323C PEP7 "Multivalent adaptor protein that facilitates vesicle-mediated vacuolar protein sorting by ensuring high-fidelity vesicle docking and fusion, which are essential for targeting of vesicles to the endosome; required for vacuole inheritance" Verified chr4:1112477-1114024 1112477-1114024 99.3% 49.46 55.97 38.40 37.75 65.73 36.45 52.72 38.07 51.09 0.19 0.15 0.21 0.42 0.21 Matched[1290]
YDR324C UTP4 "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" Verified chr4:1114430-1116760 1114430-1116760 99.3% 184.03 110.59 108.00 85.53 12.10 3.02 147.31 96.77 7.56 0.54 0.39 0.03 -3.68 -3.28 Matched[1291]
YDR325W YCG1 "Non-SMC subunit of the condensin complex (Smc2p-Smc4p-Ycs4p-Brn1p-Ycg1p); required for establishment and maintenance of chromosome condensation, chromosome segregation and for chromatin binding of the condensin complex" Verified chr4:1117121-1120228 1117121-1120228 98.7% 75.61 79.52 70.72 48.89 53.12 45.95 77.57 59.81 49.54 0.29 0.24 0.21 -0.27 0.18 Matched[1292]
YDR326C YSP2 Protein involved in programmed cell death; mutant shows resistance to cell death induced by amiodarone or intracellular acidification Verified chr4:1120604-1124920 1120604-1124920 99.1% 114.76 127.15 99.33 97.46 76.19 107.75 120.95 98.40 91.97 0.45 0.40 0.38 -0.10 0.51 Matched[1293]
YDR327W "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the verified gene SKP1" Dubious chr4:1125297-1125623 1125297-1125623 98.8% 876.16 904.02 913.31 916.41 1513.93 1083.59 890.09 914.86 1298.76 3.29 3.71 5.38 0.51 -0.07 Matched[1294]
YDR328C SKP1 "Evolutionarily conserved kinetochore protein that is part of multiple protein complexes, including the SCF ubiquitin ligase complex, the CBF3 complex that binds centromeric DNA, and the RAVE complex that regulates assembly of the V-ATPase" Verified chr4:1125429-1126013 1125429-1126013 99.0% 830.68 818.59 839.32 789.24 1246.89 903.22 824.64 814.28 1075.05 3.04 3.31 4.45 0.40 0.10 Frag>80[1294,1295]
YDR329C PEX3 Peroxisomal membrane protein (PMP) required required for the proper localization and stability of PMPs; interacts with Pex19p Verified chr4:1126265-1127590 1126265-1127590 99.2% 162.75 158.19 167.32 169.60 294.32 174.92 160.47 168.46 234.62 0.59 0.68 0.97 0.48 0.80 Matched[1296]
YDR330W UBX5 UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p Verified chr4:1127867-1129369 1127867-1129369 98.6% 128.93 124.21 151.21 137.71 288.25 247.07 126.57 144.46 267.66 0.47 0.59 1.11 0.89 1.36 Covered/w/another[1297]
YDR331W GPI8 ER membrane glycoprotein subunit of the glycosylphosphatidylinositol transamidase complex that adds glycosylphosphatidylinositol (GPI) anchors to newly synthesized proteins; human PIG-K protein is a functional homolog Verified chr4:1129583-1130818 1129583-1130818 98.9% 202.83 166.84 189.74 166.84 149.67 124.31 184.84 178.29 136.99 0.68 0.72 0.57 -0.38 -0.27 Covered/w/another[1297]
YDR332W Hypothetical protein; null mutant displays increased levels of spontaneous Rad52 foci Uncharacterized chr4:1130996-1133065 1130996-1133065 98.9% 53.76 64.02 54.24 41.54 80.14 50.82 58.89 47.89 65.48 0.22 0.19 0.27 0.45 0.30 Covered/w/another[1297]
YDR333C Putative protein of unknown function Uncharacterized chr4:1133255-1135426 1133255-1135426 99.1% 154.71 151.93 154.25 152.39 105.46 90.60 153.32 153.32 98.03 0.57 0.62 0.41 -0.65 -0.78 Covered/w/another[1297]
YDR334W SWR1 "Swi2/Snf2-related ATPase that is the structural component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A" Verified chr4:1135927-1140471 1135927-1140471 98.5% 96.02 88.42 84.63 78.15 86.64 98.25 92.22 81.39 92.44 0.34 0.33 0.38 0.18 0.82 Matched[1298]
YDR335W MSN5 "Karyopherin involved in nuclear import and export; shown to be responsible for nuclear import of replication protein A and for export of several proteins including Swi6p, Far1p, and Pho4p; cargo dissociation involves binding to RanGTP" Verified chr4:1141162-1144836 1141162-1144836 98.9% 209.95 210.23 191.79 191.24 242.70 225.09 210.09 191.52 233.89 0.78 0.78 0.97 0.29 0.69 Frag>80[1299,1300]
YDR336W Putative protein of unknown function; sumoylated under stress conditions in a genome wide study; YDR336W is not an essential gene Uncharacterized chr4:1145086-1146030 1145086-1146030 98.9% 92.06 110.25 98.48 72.79 114.54 44.96 101.16 85.63 79.75 0.37 0.35 0.33 -0.10 -0.44 Matched[1301]
YDR337W MRPS28 Mitochondrial ribosomal protein of the small subunit Verified chr4:1146313-1147173 1146313-1147173 98.4% 319.86 270.29 272.65 284.45 369.43 191.21 295.07 278.55 280.32 1.09 1.13 1.16 0.01 -0.09 Matched[1302]
YDR338C Hypothetical protein Uncharacterized chr4:1147373-1149460 1147373-1149460 98.9% 63.91 63.91 64.40 41.64 54.71 45.51 63.91 53.02 50.11 0.24 0.22 0.21 -0.08 0.23 Matched[1303]
YDR339C FCF1 Essential nucleolar protein that is a component of the SSU (small subunit) processome involved in the pre-rRNA processing steps of 40S ribosomal subunit biogenesis; contains a PINc domain; copurifies with Faf1p Verified chr4:1149945-1150514 1149945-1150514 99.3% 342.91 238.62 265.13 273.97 146.71 137.87 290.76 269.55 142.29 1.07 1.09 0.59 -0.92 -0.73 Matched[1304]
YDR340W Putative protein of unknown function Dubious chr4:1150875-1151177 1150875-1151177 50.7% 0.00 0.00 0.00 0.00 0.00 6.51 0.00 0.00 3.26 0.00 0.00 0.01 Inf -0.18
YDR341C "Arginyl-tRNA synthetase, proposed to be cytoplasmic but the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr4:1151797-1153620 1151797-1153620 99.1% 799.67 625.35 669.06 662.98 241.84 212.51 712.51 666.02 227.17 2.63 2.70 0.94 -1.55 -0.83 Frag>80[1305,1306,1307]
YDR342C HXT7 "High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt6p, expressed at high basal levels relative to other HXTs, expression repressed by high glucose levels" Verified chr4:1154210-1155922 1154210-1155922 1.7% 4090.14 8146.48 11087.32 13588.73 17509.86 8687.32 6118.31 12338.03 13098.59 22.59 50.08 54.27 0.09 -1.44 Frag<80[1307]
YDR343C HXT6 "High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt7p, expressed at high basal levels relative to other HXTs, repression of expression by high glucose requires SNF3" Verified chr4:1159602-1161314 1159602-1161314 1.7% 201.68 1378.15 1176.47 1613.45 1781.51 1210.08 789.92 1394.96 1495.80 2.92 5.66 6.20 0.10 -0.87 Frag<80[1309]
YDR344C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:1162000-1162443 1162000-1162443 98.6% 13.71 18.27 18.27 11.42 18.27 20.56 15.99 14.85 19.42 0.06 0.06 0.08 0.39 -0.88 Frag<80[1310,1311]
YDR345C HXT3 "Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions" Verified chr4:1162951-1164654 1162951-1164654 66.5% 2270.72 1424.16 1716.93 1632.28 157.85 24.69 1847.44 1674.60 91.27 6.82 6.80 0.38 -4.20 -4.16 Frag>80[1311,1312]
YDR346C SVF1 "Protein with a potential role in cell survival pathways, required for the diauxic growth shift; expression in mammalian cells increases survival under conditions inducing apoptosis" Verified chr4:1167208-1168653 1167208-1168653 99.2% 607.77 475.34 473.25 386.13 332.46 223.04 541.56 429.69 277.75 2.00 1.74 1.15 -0.63 -0.46 Matched[1314]
YDR347W MRP1 "Mitochondrial ribosomal protein of the small subunit; MRP1 exhibits genetic interactions with PET122, encoding a COX3-specific translational activator, and with PET123, encoding a small subunit mitochondrial ribosomal protein" Verified chr4:1169172-1170137 1169172-1170137 98.6% 288.81 312.97 370.73 298.27 401.19 318.22 300.89 334.50 359.71 1.11 1.36 1.49 0.10 0.33 Matched[1315]
YDR348C Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and bud neck; potential Cdc28p substrate Uncharacterized chr4:1170320-1171819 1170320-1171819 98.9% 217.69 219.03 187.36 167.14 172.53 146.92 218.36 177.25 159.73 0.81 0.72 0.66 -0.15 0.04 Matched[1316]
YDR349C YPS7 "Putative GPI-anchored aspartic protease, located in the cytoplasm and endoplasmic reticulum" Verified chr4:1172380-1174170 1172380-1174170 98.8% 255.33 231.61 195.45 170.03 110.15 90.95 243.47 182.74 100.55 0.90 0.74 0.42 -0.86 -0.18 Frag>80[1317,1318,1319]
YDR350C ATP22 "Mitochondrial inner membrane protein required for assembly of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis" Verified chr4:1176332-1178167 1176332-1178167 99.0% 75.91 74.26 66.56 69.86 80.31 79.21 75.08 68.21 79.76 0.28 0.28 0.33 0.23 0.50 Matched[1321]
YDR351W SBE2 Protein involved in the transport of cell wall components from the Golgi to the cell surface; required for bud growth Verified chr4:1178659-1181253 1178659-1181253 98.8% 104.54 95.96 85.03 70.21 88.55 78.40 100.25 77.62 83.47 0.37 0.32 0.35 0.10 0.22 Matched[1322]
YDR352W Putative protein of unknown function Uncharacterized chr4:1181794-1182747 1181794-1182747 98.8% 150.66 174.01 154.91 131.56 148.54 71.09 162.33 143.24 109.81 0.60 0.58 0.45 -0.38 -0.09 Frag>80[1323,1324]
YDR353W TRR1 "Cytoplasmic thioredoxin reductase, key regulatory enzyme that determines the redox state of the thioredoxin system, which acts as a disulfide reductase system and protects cells against both oxidative and reductive stress" Verified chr4:1183292-1184251 1183292-1184251 97.6% 1586.56 980.53 1670.85 1251.53 1763.67 1360.36 1283.54 1461.19 1562.02 4.74 5.93 6.47 0.10 0.42 Matched[1325]
YDR354W TRP4 "Anthranilate phosphoribosyl transferase of the tryptophan biosynthetic pathway, catalyzes the phosphoribosylation of anthranilate, subject to the general control system of amino acid biosynthesis" Verified chr4:1184740-1185882 1184740-1185882 98.8% 195.79 284.39 227.69 201.99 188.70 150.61 240.09 214.84 169.66 0.89 0.87 0.70 -0.34 -0.09 Matched[1326]
YDR354C-A "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; completely overlaps TRP4; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr4:1185132-1185275 1185132-1185275 99.1% 182.19 252.26 259.27 154.16 112.12 140.15 217.23 206.72 126.13 0.80 0.84 0.52 -0.71 NaN Matched[1326]
YDR356W SPC110 "Inner plaque spindle pole body (SPB) component, ortholog of human kendrin; involved in connecting nuclear microtubules to SPB; interacts with Tub4p-complex and calmodulin; phosphorylated by Mps1p in cell cycle-dependent manner" Verified chr4:1186100-1188934 1186100-1188934 98.5% 152.61 150.10 127.53 121.44 123.59 91.35 151.36 124.49 107.47 0.56 0.51 0.45 -0.21 -0.14 Matched[1327]
YDR355C Hypothetical protein; open reading frame overlaps 5' end of essential SPC110 gene encoding an inner plaque spindle pole body component Dubious chr4:1186060-1186362 1186060-1186362 98.5% 100.52 87.11 77.06 77.06 70.36 53.61 93.82 77.06 61.99 0.35 0.31 0.26 -0.31 -0.11 Covered/w/another[1327]
YDR357C Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern Uncharacterized chr4:1189192-1189560 1189192-1189560 99.5% 348.66 359.55 324.14 250.60 716.38 275.11 354.10 287.37 495.74 1.31 1.17 2.05 0.79 0.07 Matched[1328]
YDR358W GGA1 "Golgi-localized protein with homology to gamma-adaptin, interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner in order to facilitate traffic through the late Golgi" Verified chr4:1190052-1191725 1190052-1191725 98.7% 98.03 151.28 162.17 162.17 498.02 462.32 124.66 162.17 480.17 0.46 0.66 1.99 1.57 1.38 Matched[1329]
YDR360W OPI7 "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene VID21/YDR359C." Dubious chr4:1194591-1194977 1194591-1194977 98.8% 47.10 78.50 54.95 52.33 31.40 49.72 62.80 53.64 40.56 0.23 0.22 0.17 -0.40 -0.13 Covered/w/another[1330]
YDR359C EAF1 Component of the NuA4 histone acetyltransferase complex Verified chr4:1191929-1194877 1191929-1194877 99.1% 144.76 131.07 121.49 99.24 87.95 80.76 137.91 110.36 84.36 0.51 0.45 0.35 -0.39 0.27 Covered/w/another[1330]
YDR361C BCP1 "Essential protein involved in nuclear export of Mss4p, which is a lipid kinase that generates phosphatidylinositol 4,5-biphosphate and plays a role in actin cytoskeleton organization and vesicular transport" Verified chr4:1195404-1196255 1195404-1196255 99.2% 330.10 154.99 191.67 124.23 23.66 5.92 242.54 157.95 14.79 0.90 0.64 0.06 -3.42 -3.79 Covered/w/another[1330]
YDR362C TFC6 One of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); part of TFIIIC TauB domain that binds BoxB promoter sites of tRNA and other genes; cooperates with Tfc3p in DNA binding; human homolog is TFIIIC-110 Verified chr4:1196671-1198689 1196671-1198689 99.2% 73.89 83.38 63.41 43.94 91.37 61.91 78.64 53.67 76.64 0.29 0.22 0.32 0.51 0.59 Matched[1331]
YDR363W ESC2 "Protein involved in mating-type locus silencing, interacts with Sir2p; probably functions to recruit or stabilize Sir proteins" Verified chr4:1199175-1200545 1199175-1200545 98.5% 96.97 88.09 90.31 80.69 101.42 92.53 92.53 85.50 96.97 0.34 0.35 0.40 0.18 0.53 Covered[1332]
YDR363W-A SEM1 Component of the lid subcomplex of the regulatory subunit of the 26S proteasome; ortholog of human DSS1 Verified chr4:1202120-1202389 1202120-1202389 98.3% 1119.17 991.05 1085.26 964.67 2652.85 1533.68 1055.11 1024.96 2093.26 3.89 4.16 8.67 1.03 0.42 Matched[1333]
YDR364C CDC40 "Pre-mRNA splicing factor, important for catalytic step II of pre-mRNA splicing and plays a role in cell cycle progression; required for DNA synthesis during mitosis and meiosis; has WD repeats" Verified chr4:1202835-1204202 1202835-1204202 99.1% 104.00 113.59 83.35 69.33 53.84 38.35 108.79 76.34 46.10 0.40 0.31 0.19 -0.73 -0.45 Matched[1334]
YDR365C ESF1 Nucleolar protein involved in pre-rRNA processing; depletion causes severely decreased 18S rRNA levels Verified chr4:1204489-1206375 1204489-1206375 99.4% 612.84 742.34 502.00 386.89 334.13 198.24 677.59 444.44 266.19 2.50 1.80 1.10 -0.74 -0.78 Frag>80[1335,1336]
YDR366C Hypothetical protein Uncharacterized chr4:1212430-1212828 1212430-1212828 59.6% 42.05 37.84 37.84 50.46 37.84 16.82 39.94 44.15 27.33 0.15 0.18 0.11 -0.69 0.21 Frag<80[1338]
YDR367W Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern Uncharacterized chr4:1212840-1213606 1212840-1212869,1212971-1213606 99.1% 224.30 228.85 272.80 184.90 221.27 165.19 226.57 228.85 193.23 0.84 0.93 0.80 -0.24 -0.08 Frag>80[1338,1339]
YDR368W YPR1 "2-methylbutyraldehyde reductase, may be involved in isoleucine catabolism" Verified chr4:1213896-1214834 1213896-1214834 98.7% 629.14 744.60 625.90 671.22 915.11 784.53 686.87 648.56 849.82 2.54 2.63 3.52 0.39 0.78 Matched[1340]
YDR369C XRS2 "Protein required for DNA repair; component of the Mre11 complex, which is involved in double strand breaks, meiotic recombination, telomere maintenance, and checkpoint signaling" Verified chr4:1215008-1217572 1215008-1217572 99.3% 39.27 36.12 33.77 32.98 47.12 38.09 37.70 33.38 42.60 0.14 0.14 0.18 0.35 0.17 Matched[1341]
YDR370C Putative protein of unknown function Uncharacterized chr4:1217774-1219102 1217774-1219102 99.1% 132.08 125.25 119.94 86.54 49.34 25.81 128.66 103.24 37.57 0.47 0.42 0.16 -1.46 -1.02 Matched[1342]
YDR371W CTS2 Sporulation-specific chitinase Uncharacterized chr4:1219405-1220940 1219405-1220940 98.9% 104.68 130.36 133.65 106.00 185.00 111.26 117.52 119.82 148.13 0.43 0.49 0.61 0.31 0.24 Matched[1343]
YDR371C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completeley overlaps the uncharacterized gene CTS2/YDR371W; identified by expression profiling and mass spectrometry" Dubious chr4:1219501-1219605 1219501-1219605 98.3% 77.48 48.43 67.80 87.17 96.85 58.11 62.95 77.48 77.48 0.23 0.31 0.32 0.00 NaN Covered/w/another[1343]
YDR372C VPS74 Non-essential protein of unknown function involved in vacuolar protein sorting; belongs to a family of cytosolic Golgi-associated proteins suggesting that it may play a role in secretion; also detected in the nucleus Verified chr4:1221104-1222141 1221104-1222141 99.3% 684.77 720.66 650.82 599.42 451.99 262.85 702.72 625.12 357.42 2.59 2.54 1.48 -0.81 -0.97 Matched[1344]
YDR373W FRQ1 N-myristoylated calcium-binding protein that may have a role in intracellular signaling through its regulation of the phosphatidylinositol 4-kinase Pik1p; member of the recoverin/frequenin branch of the EF-hand superfamily Verified chr4:1222751-1223323 1222751-1223323 98.8% 429.42 409.98 429.42 436.49 874.75 387.01 419.70 432.96 630.88 1.55 1.76 2.61 0.54 -0.00 Matched[1345]
YDR374C Putative protein of unknown function Uncharacterized chr4:1223466-1224386 1223466-1224386 99.4% 2.19 2.19 2.19 2.19 7.65 10.93 2.19 2.19 9.29 0.01 0.01 0.04 2.09 1.07 Frag<80[1346,1347]
YDR374W-A Putative protein of unknown function Uncharacterized chr4:1224749-1225018 1224749-1225018 98.5% 229.36 274.48 251.92 274.48 612.88 372.24 251.92 263.20 492.56 0.93 1.07 2.04 0.90 NaN Matched[1347]
YDR375C BCS1 "Protein of the mitochondrial inner membrane that functions as an ATP-dependent chaperone, required for the incorporation of the Rip1p and Qcr10p subunits into the cytochrome bc(1) complex; member of the CDC48/PAS1/SEC18 ATPase family" Verified chr4:1225158-1226528 1225158-1226528 99.1% 158.30 161.98 164.19 166.40 167.13 103.08 160.14 165.29 135.10 0.59 0.67 0.56 -0.29 0.01 Matched[1348]
YDR376W ARH1 "Oxidoreductase of the mitochondrial inner membrane, involved in cytoplasmic and mitochondrial iron homeostasis and required for activity of Fe-S cluster-containing enzymes; one of the few mitochondrial proteins essential for viability" Verified chr4:1226814-1228295 1226814-1228295 98.7% 131.95 147.00 125.80 120.33 206.48 138.79 139.48 123.07 172.63 0.51 0.50 0.72 0.49 0.51 Frag>80[1349,1350]
YDR377W ATP17 "Subunit f of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis" Verified chr4:1228603-1228908 1228603-1228908 98.8% 869.90 988.97 1005.51 1359.43 2517.09 1478.50 929.44 1182.47 1997.79 3.43 4.80 8.28 0.76 -0.42 Matched[1351]
YDR378C LSM6 "Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA" Verified chr4:1229341-1229601 1229341-1229601 99.2% 981.17 768.71 985.03 753.26 710.77 463.54 874.94 869.15 587.16 3.23 3.53 2.43 -0.57 -1.10 Matched[1352]
YDR379W RGA2 "GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth" Verified chr4:1230159-1233188 1230159-1233188 98.8% 118.63 140.69 105.93 112.28 138.35 128.66 129.66 109.11 133.50 0.48 0.44 0.55 0.29 0.28 Matched[1353]
YDR379C-A Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36. Uncharacterized chr4:1233270-1233509 1233270-1233509 99.1% 109.32 227.05 231.25 210.23 1135.25 458.30 168.19 220.74 796.78 0.62 0.90 3.30 1.85 0.91 Matched[1354]
YDR380W ARO10 "Phenylpyruvate decarboxylase, catalyzes decarboxylation of phenylpyruvate to phenylacetaldehyde, which is the first specific step in the Ehrlich pathway" Verified chr4:1234210-1236117 1234210-1236117 98.9% 230.97 339.04 274.94 337.45 3085.29 2170.40 285.01 306.20 2627.85 1.05 1.24 10.89 3.10 3.10 Matched[1356]
YDR381W YRA1 "Nuclear protein that binds to RNA and to Mex67p, required for export of poly(A)+ mRNA from the nucleus; member of the REF (RNA and export factor binding proteins) family; another family member, Yra2p, can substitute for Yra1p function" Verified chr4:1236550-1237996 1236550-1236834,1237601-1237996 98.1% 1796.86 1585.73 1954.08 1849.26 1456.95 943.35 1691.29 1901.67 1200.15 6.24 7.72 4.97 -0.66 -1.58 Frag>80[1357,1358]
YDR381C-A "Protein of unknown function, localized to the mitochondrial outer membrane" Verified chr4:1238304-1238842 1238304-1238622,1238817-1238842 99.2% 277.54 400.24 280.46 219.11 484.97 239.56 338.89 249.79 362.26 1.25 1.01 1.50 0.54 -0.22 Matched[1359]
YDR382W RPP2B "Ribosomal protein P2 beta, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm" Verified chr4:1239484-1239816 1239484-1239816 96.9% 10990.19 8784.72 10379.97 9367.06 4971.61 3992.77 9887.46 9873.52 4482.19 36.50 40.08 18.57 -1.14 -2.09 Matched[1360]
YDR383C NKP1 "Non-essential kinetochore protein, subunit of the Ctf19 central kinetochore complex (Ctf19p-Mcm21p-Okp1p-Mcm22p-Mcm16p-Ctf3p-Chl4p-Mcm19p-Nkp1p-Nkp2p-Ame1p-Mtw1p)" Verified chr4:1239952-1240668 1239952-1240668 99.4% 151.47 155.68 143.06 159.89 136.04 72.93 153.58 151.47 104.49 0.57 0.61 0.43 -0.54 -0.87 Matched[1361]
YDR384C ATO3 "Plasma membrane protein, regulation pattern suggests a possible role in export of ammonia from the cell; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family of putative transporters" Verified chr4:1241196-1242023 1241196-1242023 98.5% 214.54 254.99 192.47 129.95 79.69 39.23 234.77 161.21 59.46 0.87 0.65 0.25 -1.44 -1.17 Matched[1362]
YDR385W EFT2 "Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin" Verified chr4:1243222-1245750 1243222-1245750 1.7% 3531.46 2741.53 2811.23 2393.03 859.63 906.10 3136.50 2602.13 882.87 11.58 10.56 3.66 -1.56 -1.72 Frag<80[1364,1365,1366,1367,1368,1369]
YDR386W MUS81 "Helix-hairpin-helix protein, involved in DNA repair and replication fork stability; functions as an endonuclease in complex with Mms4p; interacts with Rad54p" Verified chr4:1246076-1247974 1246076-1247974 98.6% 73.19 75.86 61.97 49.15 71.58 35.79 74.52 55.56 53.69 0.28 0.23 0.22 -0.05 0.10 Matched[1370]
YDR387C "Putative transporter, member of the sugar porter family; YDR387C is not an essential gene" Uncharacterized chr4:1248146-1249813 1248146-1249813 98.8% 81.34 121.40 80.12 92.26 126.86 108.05 101.37 86.19 117.45 0.37 0.35 0.49 0.45 0.38 Matched[1371]
YDR388W RVS167 "Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) involved in regulation of actin cytoskeleton, endocytosis, and viability following starvation or osmotic stress; homolog of mammalian amphiphysin" Verified chr4:1250178-1251626 1250178-1251626 98.4% 572.38 756.86 566.77 621.48 807.37 822.80 664.62 594.13 815.08 2.45 2.41 3.38 0.46 0.86 Matched[1372]
YDR389W SAC7 "GTPase activating protein (GAP) for Rho1p, involved in signaling to the actin cytoskeleton, null mutations suppress tor2 mutations and temperature sensitive mutations in actin; potential Cdc28p substrate" Verified chr4:1252529-1254493 1252529-1254493 98.8% 155.01 139.05 152.95 114.84 138.02 101.97 147.03 133.90 119.99 0.54 0.54 0.50 -0.16 0.51 Covered/w/another[1373]
YDR390C UBA2 "Nuclear protein that acts as a heterodimer with Aos1p to activate Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability" Verified chr4:1254929-1256839 1254929-1256839 99.1% 236.53 214.35 213.82 211.18 132.52 132.52 225.44 212.50 132.52 0.83 0.86 0.55 -0.68 -0.18 Covered/w/another[1373]
YDR391C Hypothetical protein Uncharacterized chr4:1257350-1258048 1257350-1258048 99.0% 154.61 291.89 200.85 244.20 671.92 442.17 223.25 222.53 557.05 0.82 0.90 2.31 1.32 1.08 Frag>80[1374,1375,1376]
YDR392W SPT3 "Subunit of the SAGA and SAGA-like transcriptional regulatory complexes, interacts with Spt15p to activate transcription of some RNA polymerase II-dependent genes, also functions to inhibit transcription at some promoters" Verified chr4:1258688-1259701 1258688-1259701 98.3% 138.40 125.37 130.38 115.34 187.55 129.38 131.88 122.86 158.46 0.49 0.50 0.66 0.37 0.37 Covered/w/another[1377]
YDR393W SHE9 "Mitochondrial inner membrane protein required for normal mitochondrial morphology, may be involved in fission of the inner membrane; forms a homo-oligomeric complex" Verified chr4:1259893-1261263 1259893-1261263 98.6% 105.03 125.74 115.39 105.03 135.36 104.29 115.39 110.21 119.83 0.43 0.45 0.50 0.12 0.17 Covered/w/another[1377]
YDR394W RPT3 One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; substrate of N-acetyltransferase B Verified chr4:1261673-1262959 1261673-1262959 98.7% 500.77 415.73 543.29 481.09 727.54 537.78 458.25 512.19 632.66 1.69 2.08 2.62 0.30 0.87 Matched[1378]
YDR395W SXM1 "Nuclear transport factor (karyopherin) involved in protein transport between the cytoplasm and nucleoplasm; similar to Nmd5p, Cse1p, Lph2p, and the human cellular apoptosis susceptibility protein, CAS1" Verified chr4:1263316-1266150 1263316-1266150 98.9% 302.66 234.92 239.56 214.25 58.11 58.46 268.79 226.90 58.29 0.99 0.92 0.24 -1.96 -1.10 Frag>80[1379,1380]
YDR396W Dubious open reading frame unlikely to encode a functional protein; extensively overlaps essential NCB2 gene encoding the beta subunit of the NC2 dimeric histone-fold complex Dubious chr4:1266287-1266787 1266287-1266787 99.3% 550.80 394.00 522.66 387.97 331.69 178.91 472.40 455.31 255.30 1.74 1.85 1.06 -0.83 -0.30 Matched[1380]
YDR397C NCB2 Subunit of a heterodimeric NC2 transcription regulator complex with Bur6p; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2beta Verified chr4:1266358-1266890 1266358-1266761,1266854-1266890 99.3% 548.15 401.98 511.61 365.44 338.03 189.57 475.07 438.52 263.80 1.75 1.78 1.09 -0.73 -0.85 Frag>80[1380,1381]
YDR398W UTP5 "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" Verified chr4:1267463-1269394 1267463-1269394 98.6% 225.68 148.53 160.07 114.94 19.94 11.02 187.10 137.51 15.48 0.69 0.56 0.06 -3.15 -2.42 Frag>80[1381,1382,1383]
YDR399W HPT1 "Dimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation of both inosine monophosphate and guanosine monophosphate; mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome" Verified chr4:1270060-1270725 1270060-1270725 98.6% 1596.34 947.45 1440.97 737.24 173.65 30.46 1271.90 1089.11 102.06 4.70 4.42 0.42 -3.42 -4.02 Matched[1384]
YDR400W URH1 "Uridine nucleosidase (uridine-cytidine N-ribohydrolase), cleaves N-glycosidic bonds in nucleosides; involved in recycling pyrimidine deoxy- and ribonucleosides via the pyrimidine salvage pathway" Verified chr4:1271055-1272077 1271055-1272077 98.9% 170.09 171.08 174.04 163.16 114.71 63.29 170.58 168.60 89.00 0.63 0.68 0.37 -0.92 -0.57 Matched[1385]
YDR401W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:1272215-1272778 1272215-1272778 99.1% 14.32 12.53 10.74 5.37 14.32 7.16 13.42 8.05 10.74 0.05 0.03 0.04 0.42 0.03 Overlap[1385]
YDR402C DIT2 "N-formyltyrosine oxidase, sporulation-specific microsomal enzyme involved in the production of N,N-bisformyl dityrosine required for spore wall maturation, homologous to cytochrome P-450s" Verified chr4:1272226-1273695 1272226-1273695 98.9% 9.63 8.25 9.63 2.06 8.25 3.44 8.94 5.85 5.85 0.03 0.02 0.02 0.00 0.98 Overlap[1385]
YDR403W DIT1 "Sporulation-specific enzyme required for spore wall maturation, involved in the production of a soluble LL-dityrosine-containing precursor of the spore wall; transcripts accumulate at the time of prospore enclosure" Verified chr4:1274594-1276204 1274594-1276204 98.8% 7.54 6.28 8.79 9.42 28.90 23.24 6.91 9.11 26.07 0.03 0.04 0.11 1.52 0.95 Frag<80[1386]
YDR404C RPB7 RNA polymerase II subunit B16; forms two subunit dissociable complex with Rpb4p Verified chr4:1276646-1277161 1276646-1277161 99.0% 395.37 393.41 463.87 379.71 544.12 295.55 394.39 421.79 419.83 1.46 1.71 1.74 -0.01 0.15 Matched[1387]
YDR405W MRP20 Mitochondrial ribosomal protein of the large subunit Verified chr4:1277638-1278429 1277638-1278429 98.2% 266.18 258.47 264.89 232.75 254.61 171.02 262.32 248.82 212.82 0.97 1.01 0.88 -0.23 -0.09 Matched[1388]
YDR406W PDR15 "Plasma membrane ATP binding cassette (ABC) transporter, multidrug transporter and general stress response factor implicated in cellular detoxification; regulated by Pdr1p, Pdr3p and Pdr8p; promoter contains a PDR responsive element" Verified chr4:1279202-1283791 1279202-1283791 98.7% 104.90 113.07 183.96 140.90 446.76 540.62 108.98 162.43 493.69 0.40 0.66 2.05 1.60 2.15 Frag>80[1389,1390]
YDR406W-A Dubious open reading frame unlikely to encode a functional protein; identified by fungal homology and RT-PCR Dubious chr4:1283791-1284036 1283791-1284036 99.5% 81.70 122.55 114.38 40.85 408.51 204.26 102.13 77.62 306.38 0.38 0.32 1.27 1.98 NaN Covered/w/another[1391]
YDR407C TRS120 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic Verified chr4:1284061-1287930 1284061-1287930 99.1% 106.85 116.76 110.24 89.91 97.47 92.52 111.81 100.08 95.00 0.41 0.41 0.39 -0.08 0.18 Matched[1391]
YDR408C ADE8 "Phosphoribosyl-glycinamide transformylase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway" Verified chr4:1288207-1288851 1288207-1288851 98.8% 870.70 773.43 825.21 688.72 368.68 219.64 822.07 756.96 294.16 3.03 3.07 1.22 -1.36 -1.43 Frag>80[1392,1393]
YDR409W SIZ1 SUMO/Smt3 ligase that promotes the attachment of sumo (Smt3p; small ubiquitin-related modifier) to proteins; binds Ubc9p and may bind septins; specifically required for sumoylation of septins in vivo; localized to the septin ring Verified chr4:1289398-1292112 1289398-1292112 97.8% 79.06 94.50 76.43 60.24 94.12 97.51 86.78 68.33 95.81 0.32 0.28 0.40 0.49 0.84 Frag>80[1394,1395]
YDR410C STE14 "Farnesyl cysteine-carboxyl methyltransferase, mediates the carboxyl methylation step during C-terminal CAAX motif processing of a-factor and RAS proteins in the endoplasmic reticulum, localizes to the ER membrane" Verified chr4:1292364-1293083 1292364-1293083 98.8% 333.27 291.09 310.78 271.40 201.09 99.84 312.18 291.09 150.47 1.15 1.18 0.62 -0.95 -1.35 Matched[1396]
YDR411C DFM1 ER localized derlin-like family member involved in ER stress and homeostasis; not involved in ERAD or substrate retrotranslocation; interacts with CDC48; contains four transmembrane domains and two SHP boxes Verified chr4:1293361-1294386 1293361-1294386 98.8% 260.46 265.40 268.35 196.33 251.58 129.24 262.93 232.34 190.41 0.97 0.94 0.79 -0.29 -0.23 Matched[1397]
YDR412W Protein required for cell viability Uncharacterized chr4:1294685-1295392 1294685-1295392 98.0% 330.13 220.57 201.83 193.18 40.37 12.97 275.35 197.50 26.67 1.02 0.80 0.11 -2.89 -2.70 Covered/w/another[1398]
YDR413C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the essential uncharacterized ORF YDR412W that is implicated in rRNA processing" Dubious chr4:1294828-1295403 1294828-1295403 97.9% 363.37 219.79 228.66 209.16 39.00 12.41 291.58 218.91 25.70 1.08 0.89 0.11 -3.09 -0.31 Covered/w/another[1398]
YDR414C ERD1 "Predicted membrane protein required for the retention of lumenal endoplasmic reticulum proteins; mutants secrete the endogenous ER protein, BiP (Kar2p)" Verified chr4:1295590-1296678 1295590-1296678 98.9% 155.08 144.86 159.72 111.43 137.43 55.72 149.97 135.58 96.58 0.55 0.55 0.40 -0.49 -1.08 Covered/w/another[1398]
YDR415C Putative protein of unknown function Uncharacterized chr4:1297029-1298153 1297029-1298153 99.0% 108.60 137.32 108.60 97.83 192.06 106.80 122.96 103.21 149.43 0.45 0.42 0.62 0.53 0.79 Covered/w/another[1398]
YDR416W SYF1 Component of the spliceosome complex involved in pre-mRNA splicing; involved in regulation of cell cycle progression; similar to Drosophila crooked neck protein Verified chr4:1298424-1301003 1298424-1301003 98.7% 67.15 68.33 58.51 42.81 51.05 37.70 67.74 50.66 44.38 0.25 0.21 0.18 -0.19 0.21 Matched[1399]
YDR418W RPL12B "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Ap; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins" Verified chr4:1301608-1302105 1301608-1302105 75.5% 7765.17 6326.98 7119.19 5545.41 1640.23 1119.18 7046.08 6332.30 1379.71 26.01 25.70 5.72 -2.20 -2.96 Frag>80[1400,1401,1402]
YDR417C Hypothetical protein Dubious chr4:1301547-1301918 1301547-1301918 84.0% 6429.03 5151.55 6307.36 4799.36 1443.97 1014.94 5790.29 5553.36 1229.46 21.37 22.54 5.09 -2.18 -0.00 Frag>80[1400,1401]
YDR419W RAD30 "DNA polymerase eta, involved in the predominantly error-free bypass replication of DNA lesions, catalyzes the efficient and accurate synthesis of DNA opposite cyclobutane pyrimidine dimers; homolog of human POLH and bacterial DinB proteins" Verified chr4:1303166-1305064 1303166-1305064 98.7% 53.33 61.87 46.93 45.87 46.93 31.47 57.60 46.40 39.20 0.21 0.19 0.16 -0.24 -0.13 Matched[1403]
YDR420W HKR1 "Serine/threonine rich cell surface protein; osmosensor; involved in the regulation of cell wall beta-1,3 glucan synthesis, bud site selection and hyperosmotic response; overexpression confers resistance to Hansenula mrakii killer toxin HM-1" Verified chr4:1306259-1311667 1306259-1311667 82.2% 128.95 116.57 113.42 90.46 42.08 45.23 122.76 101.94 43.66 0.45 0.41 0.18 -1.22 -0.25 Frag<80[1404]
YDR421W ARO80 Zinc finger transcriptional activator of the Zn2Cys6 family; activates transcription of aromatic amino acid catabolic genes in the presence of aromatic amino acids Verified chr4:1312032-1314884 1312032-1314884 98.6% 52.59 52.59 40.16 46.55 107.32 87.78 52.59 43.36 97.55 0.19 0.18 0.40 1.17 1.54 Covered/w/another[1405]
YDR422C SIP1 "Alternate beta-subunit of the Snf1p kinase complex, may confer substrate specificity; vacuolar protein containing KIS (Kinase-Interacting Sequence) and ASC (Association with Snf1 kinase Complex) domains involved in protein interactions" Verified chr4:1315318-1317765 1315318-1317765 98.9% 90.43 102.81 90.84 75.15 120.98 97.03 96.62 82.99 109.01 0.36 0.34 0.45 0.39 0.83 Covered/w/another[1405]
YDR423C CAD1 "AP-1-like bZIP transcriptional activator involved in stress responses, iron metabolism, and pleiotropic drug resistance; controls a set of genes involved in stabilizing proteins; binds consensus sequence TTACTAA; 5' UTR contains uORFs" Verified chr4:1318038-1319267 1318038-1319267 99.1% 137.05 128.03 120.64 119.00 217.48 176.45 132.54 119.82 196.96 0.49 0.49 0.82 0.72 1.23 Covered/w/another[1405]
YDR424C DYN2 "Cytoplasmic light chain dynein, microtubule motor protein; proposed to be involved in the assembly of the nuclear pore complex" Verified chr4:1319379-1319833 1319379-1319609,1319690-1319712,1319809-1319833 99.4% 302.84 306.44 295.63 259.58 540.78 277.60 304.64 277.60 409.19 1.12 1.13 1.70 0.56 -0.09 Matched[1406]
YDR425W SNX41 "Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golgi endosome to the trans-Golgi network; forms a complex with Snx4p and Atg20p" Verified chr4:1320056-1321933 1320056-1321933 99.2% 72.47 71.94 74.08 79.45 131.52 113.81 72.20 76.77 122.67 0.27 0.31 0.51 0.68 1.32 Matched[1407]
YDR426C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF SNX41" Dubious chr4:1321621-1321998 1321621-1321998 97.4% 100.54 97.83 97.83 65.22 233.70 122.28 99.18 81.52 177.99 0.37 0.33 0.74 1.13 1.52 Covered/w/another[1407]
YDR427W RPN9 "Non-ATPase regulatory subunit of the 26S proteasome, has similarity to putative proteasomal subunits in other species; null mutant is temperature sensitive and exhibits cell cycle and proteasome assembly defects" Verified chr4:1322197-1323378 1322197-1323378 99.2% 502.52 437.68 517.03 504.23 953.86 571.63 470.10 510.63 762.74 1.74 2.07 3.16 0.58 0.38 Matched[1408]
YDR428C Putative alpha/beta-serine hydrolase belonging to the subfamily of hormone-sensitive lipase-like hydrolases Uncharacterized chr4:1323446-1324231 1323446-1324231 99.4% 129.33 128.05 107.56 97.32 92.19 51.22 128.69 102.44 71.71 0.48 0.42 0.30 -0.51 -0.10 Matched[1409]
YDR429C TIF35 "Subunit of the core complex of translation initiation factor 3(eIF3), which is essential for translation" Verified chr4:1324469-1325293 1324469-1325293 99.2% 1449.58 960.68 1201.47 1069.46 411.90 240.78 1205.13 1135.47 326.34 4.45 4.61 1.35 -1.80 -1.93 Matched[1410]
YDR431W "Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:1328382-1328693 1328382-1328693 99.1% 12.93 16.17 25.87 45.26 38.80 29.10 14.55 35.57 33.95 0.05 0.14 0.14 -0.07 0.08 Overlap[1411]
YDR430C CYM1 "Lysine-specific metalloprotease of the mitochondrial intermembrane space, member of the pitrilysin family; degrades proteins and presequence peptides cleaved from imported proteins; required for normal mitochondrial morphology" Verified chr4:1325493-1328462 1325493-1328462 99.1% 126.06 97.86 125.72 110.77 166.50 156.98 111.96 118.25 161.74 0.41 0.48 0.67 0.45 0.84 Matched[1411]
YDR432W NPL3 RNA-binding protein that carries poly(A)+ mRNA from the nucleus into the cytoplasm; dissociation from mRNAs is promoted by Mtr10p; phosphorylated by Sky1p in the cytoplasm Verified chr4:1328775-1330019 1328775-1330019 98.1% 1108.93 821.46 1194.10 1115.48 1776.41 1680.59 965.19 1154.79 1728.50 3.56 4.69 7.16 0.58 0.72 Matched[1412]
YDR433W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:1329592-1330032 1329592-1330032 96.9% 1254.17 898.51 1293.95 1205.03 1981.87 1675.34 1076.34 1249.49 1828.60 3.97 5.07 7.58 0.55 -0.14 Covered/w/another[1412]
YDR434W GPI17 Transmembrane protein subunit of the glycosylphosphatidylinositol transamidase complex that adds GPIs to newly synthesized proteins; human PIG-Sp homolog Verified chr4:1331229-1332833 1331229-1332833 99.0% 213.91 200.07 217.06 211.39 238.45 153.51 206.99 214.22 195.98 0.76 0.87 0.81 -0.13 -0.15 Matched[1414]
YDR435C PPM1 "Carboxyl methyl transferase, methylates the C terminus of the protein phosphatase 2A catalytic subunit (Pph21p or Pph22p), which is important for complex formation with regulatory subunits" Verified chr4:1332975-1333961 1332975-1333961 99.0% 124.82 149.38 128.92 136.08 268.06 188.26 137.10 132.50 228.16 0.51 0.54 0.95 0.78 0.51 Matched[1415]
YDR436W PPZ2 "Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance" Verified chr4:1334813-1336945 1334813-1336945 98.6% 60.84 68.92 79.38 81.76 163.51 168.74 64.88 80.57 166.13 0.24 0.33 0.69 1.04 1.19 Matched[1416]
YDR437W GPI19 "Subunit of GPI-GlcNAc transferase involved in synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), which is the first intermediate in glycosylphosphatidylinositol (GPI) anchor synthesis, shares similarity with mammalian PIG-P" Verified chr4:1337344-1337766 1337344-1337766 98.8% 55.04 31.11 31.11 35.90 35.90 33.50 43.08 33.50 34.70 0.16 0.14 0.14 0.05 0.58 Covered/w/another[1417]
YDR438W THI74 Mitochondrial transporter repressible by thiamine Verified chr4:1338266-1339378 1338266-1339378 99.1% 69.81 77.07 38.08 47.15 68.91 46.24 73.44 42.61 57.57 0.27 0.17 0.24 0.43 -0.07 Covered/w/another[1417]
YDR439W LRS4 Protein involved in rDNA silencing; positively charged coiled-coil protein with limited similarity to myosin Verified chr4:1339668-1340711 1339668-1340711 98.8% 85.34 75.64 70.79 63.03 86.31 66.91 80.49 66.91 76.61 0.30 0.27 0.32 0.20 0.43 Covered/w/another[1417]
YDR440W DOT1 "Nucleosomal histone H3-Lys79 methylase, associates with transcriptionally active genes, functions in gene silencing at telomeres, most likely by directly modulating chromatin structure and Sir protein localization" Verified chr4:1342485-1344233 1342485-1344233 98.7% 113.00 90.98 87.50 75.91 39.98 39.40 101.99 81.71 39.69 0.38 0.33 0.16 -1.04 -0.73 Covered/w/another[1418]
YDR441C APT2 "Apparent pseudogene, not transcribed or translated under normal conditions; encodes a protein with similarity to adenine phosphoribosyltransferase, but artificially expressed protein exhibits no enzymatic activity" Verified chr4:1344509-1345054 1344509-1345054 98.8% 209.44 226.12 190.90 100.08 124.18 81.55 217.78 145.49 102.87 0.80 0.59 0.43 -0.50 -0.90 Covered/w/another[1418]
YDR442W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:1345639-1346031 1345639-1346031 98.6% 108.40 141.95 100.66 129.05 136.79 116.14 125.17 114.85 126.47 0.46 0.47 0.52 0.14 0.44 Covered/w/another[1418]
YDR443C SSN2 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for stable association of Srb10p-Srb11p kinase; essential for transcriptional regulation Verified chr4:1345668-1349930 1345668-1349930 98.7% 67.49 82.46 67.97 89.83 42.78 76.52 74.98 78.90 59.65 0.28 0.32 0.25 -0.40 0.24 Covered/w/another[1418]
YDR444W Putative protein of unknown function Uncharacterized chr4:1350282-1352345 1350282-1352345 98.5% 128.88 122.00 126.42 93.96 58.54 53.13 125.44 110.19 55.83 0.46 0.45 0.23 -0.98 -0.40 Matched[1419]
YDR445C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:1352174-1352581 1352174-1352581 80.0% 119.51 113.38 85.80 67.42 64.35 33.71 116.45 76.61 49.03 0.43 0.31 0.20 -0.64 -0.14 Overlap[1419]
YDR446W ECM11 "Non-essential protein apparently involved in meiosis, GFP fusion protein is present in discrete clusters in the nucleus throughout mitosis; may be involved in maintaining chromatin structure" Verified chr4:1353717-1354625 1353717-1354625 98.7% 18.95 14.49 6.69 11.15 3.34 18.95 16.72 8.92 11.15 0.06 0.04 0.05 0.32 -1.00 Frag<80[1420]
YDR447C RPS17B Ribosomal protein 51 (rp51) of the small (40s) subunit; nearly identical to Rps17Ap and has similarity to rat S17 ribosomal protein Verified chr4:1354821-1355545 1354821-1355228,1355543-1355545 46.8% 6574.77 5154.75 5326.40 4468.14 1581.27 1492.85 5864.76 4897.27 1537.06 21.65 19.88 6.37 -1.67 -3.24 Frag>80[1420,1421]
YDR448W ADA2 "Transcription coactivator, component of the ADA and SAGA transcriptional adaptor/HAT (histone acetyltransferase) complexes" Verified chr4:1356057-1357361 1356057-1357361 98.4% 94.19 88.74 77.06 61.49 75.51 76.28 91.46 69.28 75.90 0.34 0.28 0.31 0.13 0.23 Matched[1422]
YDR449C UTP6 "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" Verified chr4:1357572-1358894 1357572-1358894 99.5% 174.73 101.80 120.03 91.17 10.64 7.60 138.27 105.60 9.12 0.51 0.43 0.04 -3.53 -3.03 Matched[1423]
YDR450W RPS18A Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Bp and has similarity to E. coli S13 and rat S18 ribosomal proteins Verified chr4:1359915-1360790 1359915-1359961,1360397-1360790 53.1% 8028.47 6670.46 6939.50 6888.26 2536.65 2698.93 7349.47 6913.88 2617.79 27.13 28.06 10.85 -1.40 -1.97 Matched[1424]
YDR451C YHP1 "One of two homeobox transcriptional repressors (see also Yox1p), that bind to Mcm1p and to early cell cycle box (ECB) elements of cell cycle regulated genes, thereby restricting ECB-mediated transcription to the M/G1 interval" Verified chr4:1361112-1362173 1361112-1362173 98.7% 208.84 242.22 180.24 156.40 116.34 59.13 225.53 168.32 87.73 0.83 0.68 0.36 -0.94 -0.80 Matched[1425]
YDR452W PPN1 Vacuolar endopolyphosphatase with a role in phosphate metabolism; functions as a homodimer Verified chr4:1362870-1364894 1362870-1364894 98.5% 753.16 787.24 718.59 718.09 669.98 614.36 770.20 718.34 642.17 2.84 2.92 2.66 -0.16 0.39 Matched[1426]
YDR453C TSA2 "Stress inducible cytoplasmic thioredoxin peroxidase; cooperates with Tsa1p in the removal of reactive oxygen, nitrogen and sulfur species using thioredoxin as hydrogen donor; deletion enhances the mutator phenotype of tsa1 mutants" Verified chr4:1365064-1365654 1365064-1365654 98.8% 46.24 123.31 34.25 46.24 1099.55 633.70 84.78 40.25 866.62 0.31 0.16 3.59 4.43 1.57 Frag>80[1427,1428]
YDR454C GUK1 "Guanylate kinase, converts GMP to GDP; required for growth and mannose outer chain elongation of cell wall N-linked glycoproteins" Verified chr4:1366256-1366819 1366256-1366819 99.0% 1522.73 1304.17 1393.74 1393.74 927.97 872.43 1413.45 1393.74 900.20 5.22 5.66 3.73 -0.63 -0.45 Frag>80[1429,1430]
YDR456W NHX1 "Endosomal Na+/H+ exchanger, required for intracellular sequestration of Na+; required for osmotolerance to acute hypertonic shock" Verified chr4:1367477-1369378 1367477-1369378 99.1% 261.02 241.92 255.18 209.03 135.28 107.17 251.47 232.11 121.23 0.93 0.94 0.50 -0.94 -0.62 Matched[1431]
YDR455C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YDR456W" Dubious chr4:1367365-1367673 1367365-1367673 99.0% 88.30 75.21 150.43 121.00 62.13 52.32 81.76 135.71 57.23 0.30 0.55 0.24 -1.25 -0.02 Covered/w/another[1431]
YDR457W TOM1 E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators Verified chr4:1369782-1379588 1369782-1379588 98.9% 117.99 114.07 91.17 93.13 50.23 72.09 116.03 92.15 61.16 0.43 0.37 0.25 -0.59 -0.48 Frag>80[1432,1433]
YDR458C HEH2 "Inner nuclear membrane (INM) protein; contains helix-extension-helix (HEH) motif, nuclear localization signal sequence; targeting to the INM requires the Srp1p-Kap95p karyopherins and the Ran cycle" Verified chr4:1380047-1382038 1380047-1382038 99.3% 154.73 184.57 140.07 150.18 170.41 140.07 169.65 145.13 155.24 0.63 0.59 0.64 0.10 0.35 Covered/w/another[1434]
YDR459C PFA5 Palmitoyltransferase with autoacylation activity; likely functions in pathway(s) outside Ras; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain Verified chr4:1382311-1383435 1382311-1383435 99.0% 120.31 117.61 114.92 91.58 85.29 58.36 118.96 103.25 71.82 0.44 0.42 0.30 -0.52 0.16 Covered/w/another[1434]
YDR460W TFB3 "Subunit of TFIIH and nucleotide excision repair factor 3 complexes, involved in transcription initiation, required for nucleotide excision repair; ring finger protein similar to mammalian CAK and TFIIH subunit" Verified chr4:1383803-1384768 1383803-1384768 98.4% 104.19 130.50 136.81 113.66 154.70 104.19 117.34 125.24 129.45 0.43 0.51 0.54 0.05 0.19 Matched[1435]
YDR461W MFA1 "Mating pheromone a-factor, made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA2" Verified chr4:1385168-1385278 1385168-1385278 98.4% 6858.45 9559.71 7819.92 5448.30 3992.37 3204.88 8209.08 6634.11 3598.63 30.30 26.93 14.91 -0.88 -1.26 Matched[1436]
YDR461C-A Putative protein of unknown function Uncharacterized chr4:1385516-1385758 1385516-1385758 98.8% 199.90 212.39 162.42 191.57 1007.81 674.65 206.14 176.99 841.23 0.76 0.72 3.49 2.25 NaN Matched[1436]
YDR462W MRPL28 Mitochondrial ribosomal protein of the large subunit Verified chr4:1386065-1386508 1386065-1386508 98.2% 227.00 249.93 353.11 268.27 488.39 309.54 238.46 310.69 398.97 0.88 1.26 1.65 0.36 0.66 Matched[1437]
YDR463W STP1 "Transcription factor, activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes and may have a role in tRNA processing" Verified chr4:1386808-1388367 1386808-1388367 98.7% 170.18 200.71 165.63 165.63 218.25 194.21 185.44 165.63 206.23 0.68 0.67 0.85 0.32 0.95 Matched[1438]
YDR464W SPP41 Protein involved in negative regulation of expression of spliceosome components PRP4 and PRP3 Verified chr4:1388864-1393171 1388864-1393171 98.4% 176.68 134.46 116.06 110.39 52.60 79.49 155.57 113.23 66.05 0.57 0.46 0.27 -0.78 -0.31 Covered/w/another[1439]
YDR464C-A "Dubious open reading frame unlikely to encode a functional protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr4:1392484-1392672 1392484-1392672 98.7% 208.98 133.96 107.17 112.53 48.23 75.02 171.47 109.85 61.62 0.63 0.45 0.26 -0.83 NaN Covered/w/another[1439]
YDR465C RMT2 Arginine methyltransferase; ribosomal protein L12 is a substrate Verified chr4:1393328-1394566 1393328-1394566 99.2% 271.64 111.42 177.30 154.52 19.52 4.88 191.53 165.91 12.20 0.71 0.67 0.05 -3.77 -3.49 Covered/w/another[1439]
YDR466W PKH3 "Protein kinase with similarity to mammalian phosphoinositide-dependent kinase 1 (PDK1) and yeast Pkh1p and Pkh2p, two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant" Verified chr4:1395113-1397809 1395113-1397809 98.8% 151.92 145.54 123.79 128.29 152.30 141.42 148.73 126.04 146.86 0.55 0.51 0.61 0.22 0.56 Matched[1440]
YDR467C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:1397575-1397901 1397575-1397901 99.0% 225.60 250.32 185.42 145.25 336.85 259.59 237.96 165.34 298.22 0.88 0.67 1.24 0.85 -0.14 Covered/w/another[1440]
YDR468C TLG1 Essential t-SNARE that forms a complex with Tlg2p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds the docking complex VFT (Vps fifty-three) through interaction with Vps51p Verified chr4:1398018-1398692 1398018-1398692 99.5% 221.78 275.37 236.67 194.99 482.26 242.62 248.57 215.83 362.44 0.92 0.88 1.50 0.75 0.20 Frag<80[1441]
YDR469W SDC1 "Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; has similarity to C. elegans Dpy-30" Verified chr4:1399007-1399534 1399007-1399534 98.8% 243.35 228.02 193.53 199.28 216.53 107.31 235.69 196.41 161.92 0.87 0.80 0.67 -0.28 -0.83 Covered/w/another[1442]
YDR470C UGO1 Protein of unknown function; outer membrane component of the mitochondrial fusion machinery; Ugo1p bind directly to Fzo1p and Mgm1p and thereby link these two GTPases during mitochondrial fusion Verified chr4:1399698-1401206 1399698-1401206 99.2% 94.22 109.59 105.58 104.91 150.36 105.58 101.91 105.25 127.97 0.38 0.43 0.53 0.28 0.18 Matched[1442]
YDR471W RPL27B "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Ap and has similarity to rat L27 ribosomal protein" Verified chr4:1401762-1402556 1401762-1401792,1402177-1402556 91.4% 4919.25 3585.63 4224.49 3117.13 524.40 181.01 4252.44 3670.81 352.71 15.70 14.90 1.46 -3.38 -4.50 Frag>80[1443,1444,1445]
YDR472W TRS31 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic Verified chr4:1403314-1404165 1403314-1404165 98.9% 150.64 155.39 153.02 139.97 65.24 54.56 153.02 146.49 59.90 0.56 0.59 0.25 -1.29 -0.77 Covered/w/another[1446]
YDR473C PRP3 "Splicing factor, component of the U4/U6-U5 snRNP complex" Verified chr4:1404437-1405846 1404437-1405846 99.5% 93.36 102.62 89.08 81.96 124.00 83.38 97.99 85.52 103.69 0.36 0.35 0.43 0.28 0.23 Covered/w/another[1446]
YDR475C JIP4 "Protein of unknown function; previously annotated as two separate ORFs, YDR474C and YDR475C, which were merged as a result of corrections to the systematic reference sequence" Verified chr4:1407456-1410086 1407456-1410086 99.0% 106.75 169.72 106.36 112.50 193.91 224.24 138.23 109.43 209.07 0.51 0.44 0.87 0.93 1.60 Matched[1448]
YDR476C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YDR476C is not an essential gene Uncharacterized chr4:1410445-1411119 1410445-1411119 98.0% 214.61 201.01 229.72 173.80 323.43 179.85 207.81 201.76 251.64 0.77 0.82 1.04 0.32 0.47 Matched[1449]
YDR477W SNF1 "AMP-activated serine/threonine protein kinase found in a complex containing Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis" Verified chr4:1412365-1414266 1412365-1414266 98.7% 249.72 256.11 326.40 276.35 271.55 207.13 252.92 301.37 239.34 0.93 1.22 0.99 -0.33 0.24 Matched[1451]
YDR478W SNM1 "Subunit of RNase MRP, which cleaves pre-rRNA and has a role in cell cycle-regulated degradation of daughter cell-specific mRNAs; binds to the NME1 RNA subunit of RNase MRP" Verified chr4:1414567-1415163 1414567-1415163 98.6% 45.88 56.07 57.77 47.58 81.56 37.38 50.98 52.68 59.47 0.19 0.21 0.25 0.18 -0.27 Matched[1452]
YDR479C PEX29 "Peroxisomal integral membrane peroxin, involved in the regulation of peroxisomal size, number and distribution; genetic interactions suggest that Pex28p and Pex29p act at steps upstream of those mediated by Pex30p, Pex31p, and Pex32p" Verified chr4:1415202-1416866 1415202-1416866 99.0% 144.94 154.64 143.12 132.20 232.87 183.15 149.79 137.66 208.01 0.55 0.56 0.86 0.60 0.92 Matched[1453]
YDR480W DIG2 "Regulatory protein of unknown function, pheromone-inducible, involved in the regulation of mating-specific genes and the invasive growth pathway, required for MAP-kinase imposed repression, inhibits pheromone-responsive transcription" Verified chr4:1417391-1418362 1417391-1418362 98.6% 108.49 108.49 107.45 107.45 130.40 69.89 108.49 107.45 100.15 0.40 0.44 0.41 -0.10 0.05 Matched[1454]
YDR481C PHO8 "Repressible alkaline phosphatase, a glycoprotein localized to the vacuole; regulated by levels of inorganic phosphate and by a system consisting of Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides" Verified chr4:1418542-1420242 1418542-1420242 98.9% 518.24 739.92 591.93 506.35 332.81 290.02 629.08 549.14 311.42 2.32 2.23 1.29 -0.82 -0.37 Covered/w/another[1455]
YDR482C CWC21 "Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; may bind RNA; has similarity to S. pombe Cwf21p" Verified chr4:1420423-1420830 1420423-1420830 98.9% 183.34 138.74 173.43 151.13 178.38 111.49 161.04 162.28 144.94 0.59 0.66 0.60 -0.16 -0.10 Covered/w/another[1455]
YDR483W KRE2 "Alpha1,2-mannosyltransferase of the Golgi involved in protein mannosylation" Verified chr4:1421149-1422477 1421149-1422477 98.7% 1028.17 1144.02 969.48 971.01 710.34 647.85 1086.09 970.24 679.09 4.01 3.94 2.81 -0.51 -0.14 Matched[1456]
YDR484W VPS52 "Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; involved in localization of actin and chitin" Verified chr4:1422755-1424680 1422755-1424680 99.1% 61.81 67.57 67.57 56.57 90.62 60.24 64.69 62.07 75.43 0.24 0.25 0.31 0.28 0.33 Covered/w/another[1457]
YDR485C VPS72 "Htz1p-binding component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required for vacuolar protein sorting" Verified chr4:1424812-1427199 1424812-1427199 99.2% 116.45 107.17 92.40 91.98 108.01 107.17 111.81 92.19 107.59 0.41 0.37 0.45 0.22 0.50 Covered/w/another[1457]
YDR486C VPS60 Cytoplasmic and vacuolar membrane protein involved in late endosome to vacuole transport; required for normal filament maturation during pseudohyphal growth; may function in targeting specific cargo proteins for degradation Verified chr4:1427423-1428112 1427423-1428112 99.3% 271.53 277.37 236.50 240.88 383.94 208.76 274.45 238.69 296.35 1.01 0.97 1.23 0.31 0.31 Matched[1458]
YDR487C RIB3 "3,4-dihydroxy-2-butanone-4-phosphate synthase (DHBP synthase), required for riboflavin biosynthesis from ribulose-5-phosphate, also has an unrelated function in mitochondrial respiration" Verified chr4:1428346-1428972 1428346-1428972 98.9% 926.06 1087.39 863.14 793.76 553.37 403.33 1006.72 828.45 478.35 3.72 3.36 1.98 -0.79 -0.58 Matched[1459]
YDR488C PAC11 "Dynein intermediate chain, acts in the cytoplasmic dynein pathway, forms cortical cytoplasmic microtubule capture site with Num1p; null mutant is defective in nuclear migration, essential in the absence of CIN8" Verified chr4:1429180-1430781 1429180-1430781 98.9% 83.98 82.08 69.46 67.56 40.41 33.46 83.03 68.51 36.94 0.31 0.28 0.15 -0.89 0.12 Matched[1460]
YDR489W SLD5 "Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery" Verified chr4:1431004-1431888 1431004-1431888 98.8% 86.89 76.60 65.17 46.88 73.17 64.02 81.75 56.02 68.60 0.30 0.23 0.28 0.29 0.47 Matched[1461]
YDR490C PKH1 "Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; redundant with Pkh2p" Verified chr4:1431960-1434260 1431960-1434260 98.9% 90.05 109.38 99.28 80.39 197.24 188.45 99.72 89.83 192.84 0.37 0.36 0.80 1.10 1.50 Matched[1462]
YDR492W IZH1 "Membrane protein involved in zinc metabolism, member of the four-protein IZH family; transcription is regulated directly by Zap1p, expression induced by zinc deficiency and fatty acids; deletion increases sensitivity to elevated zinc" Verified chr4:1434916-1435866 1434916-1435866 99.1% 198.40 662.04 158.08 116.71 48.80 25.46 430.22 137.39 37.13 1.59 0.56 0.15 -1.89 -1.39 Matched[1463]
YDR491C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:1434492-1434983 1434492-1434983 98.8% 78.16 172.77 67.87 43.19 22.62 6.17 125.46 55.53 14.40 0.46 0.23 0.06 -1.95 0.13 Overlap[1463]
YDR493W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr4:1436209-1436580 1436209-1436580 98.3% 191.39 218.73 251.54 180.45 306.22 177.72 205.06 215.99 241.97 0.76 0.88 1.00 0.16 0.08 Matched[1464]
YDR494W RSM28 Mitochondrial ribosomal protein of the small subunit; genetic interactions suggest a possible role in promoting translation initiation Verified chr4:1436922-1438007 1436922-1438007 98.7% 281.74 297.60 298.53 304.13 466.45 261.21 289.67 301.33 363.83 1.07 1.22 1.51 0.27 -0.14 Matched[1465]
YDR495C VPS3 "Component of CORVET tethering complex; cytoplasmic protein required for the sorting and processing of soluble vacuolar proteins, acidification of the vacuolar lumen, and assembly of the vacuolar H+-ATPase" Verified chr4:1438107-1441142 1438107-1441142 99.4% 75.56 67.61 66.94 69.59 78.54 62.30 71.58 68.27 70.42 0.26 0.28 0.29 0.04 0.48 Matched[1466]
YDR496C PUF6 "Pumilio-homology domain protein that binds ASH1 mRNA at PUF consensus sequences in the 3' UTR and represses its translation, resulting in proper asymmetric localization of ASH1 mRNA" Verified chr4:1441425-1443395 1441425-1443395 99.3% 423.43 201.75 244.15 178.26 19.41 3.06 312.59 211.20 11.24 1.15 0.86 0.05 -4.23 -5.22 Matched[1467]
YDR497C ITR1 "Myo-inositol transporter with strong similarity to the minor myo-inositol transporter Itr2p, member of the sugar transporter superfamily; expression is repressed by inositol and choline via Opi1p and derepressed via Ino2p and Ino4p" Verified chr4:1443705-1445459 1443705-1445459 98.5% 966.20 922.25 990.48 1012.46 807.77 622.16 944.23 1001.47 714.96 3.49 4.07 2.96 -0.49 -0.54 Frag>80[1468,1469,1470]
YDR498C SEC20 Membrane glycoprotein v-SNARE involved in retrograde transport from the Golgi to the ER; required for N- and O-glycosylation in the Golgi but not in the ER; forms a complex with the cytosolic Tip20p Verified chr4:1445835-1446986 1445835-1446986 98.9% 129.02 156.23 142.18 133.41 163.25 110.59 142.62 137.79 136.92 0.53 0.56 0.57 -0.01 0.19 Frag>80[1470,1471]
YDR499W LCD1 Essential protein required for the DNA integrity checkpoint pathways; interacts physically with Mec1p; putative homolog of S. pombe Rad26 and human ATRIP Verified chr4:1447822-1450065 1447822-1450065 98.9% 86.55 94.66 60.40 59.05 59.95 53.19 90.60 59.73 56.57 0.33 0.24 0.23 -0.08 -0.42 Matched[1472]
YDR500C RPL37B "Protein component of the large (60S) ribosomal subunit, has similarity to Rpl37Ap and to rat L37 ribosomal protein" Verified chr4:1450190-1450845 1450190-1450449,1450839-1450845 77.1% 6873.10 6581.66 6125.08 5143.90 1544.63 1743.78 6727.38 5634.49 1644.20 24.83 22.87 6.81 -1.78 -2.33 Matched[1473]
YDR501W PLM2 Protein required for partitioning of the 2-micron plasmid Verified chr4:1451345-1452910 1451345-1452910 98.8% 49.11 50.40 55.57 22.62 38.77 42.65 49.76 39.10 40.71 0.18 0.16 0.17 0.06 0.24 Matched[1474]
YDR502C SAM2 "S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p)" Verified chr4:1453302-1454456 1453302-1454456 91.2% 272.39 294.22 296.12 209.75 170.84 146.16 283.31 252.94 158.50 1.05 1.03 0.66 -0.67 -0.18 Matched[1475]
YDR503C LPP1 "Lipid phosphate phosphatase, catalyzes Mg(2+)-independent dephosphorylation of phosphatidic acid (PA), lysophosphatidic acid, and diacylglycerol pyrophosphate; involved in control of the cellular levels of phosphatidylinositol and PA" Verified chr4:1455034-1455858 1455034-1455858 99.1% 117.41 140.64 138.20 107.62 239.71 174.89 129.03 122.91 207.30 0.48 0.50 0.86 0.75 0.66 Covered/w/another[1476]
YDR504C SPG3 Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources Verified chr4:1456303-1456686 1456303-1456686 98.7% 282.20 311.21 319.12 263.74 548.57 279.56 296.70 291.43 414.07 1.10 1.18 1.72 0.51 0.47 Covered/w/another[1476]
YDR505C PSP1 Asn and gln rich protein of unknown function; high-copy suppressor of POL1 (DNA polymerase alpha) and partial suppressor of CDC2 (polymerase delta) and CDC6 (pre-RC loading factor) mutations; overexpression results in growth inhibition Verified chr4:1456687-1459212 1456687-1459212 98.9% 156.06 176.87 165.26 182.07 319.72 317.72 166.46 173.67 318.72 0.61 0.70 1.32 0.88 0.93
YDR506C Possible membrane-localized protein Uncharacterized chr4:1459720-1461546 1459720-1461546 99.2% 33.67 50.79 41.40 41.40 73.97 82.25 42.23 41.40 78.11 0.16 0.17 0.32 0.92 1.54 Covered[1477]
YDR507C GIN4 "Protein kinase involved in bud growth and assembly of the septin ring, proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Kcc4p and Hsl1p" Verified chr4:1462350-1465778 1462350-1465778 99.2% 209.52 186.01 148.69 137.52 36.73 26.45 197.76 143.11 31.59 0.73 0.58 0.13 -2.18 -2.14 Matched[1478]
YDR509W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:1468218-1468565 1468218-1468565 99.1% 237.88 229.18 269.79 139.25 197.27 182.76 233.53 204.52 190.02 0.86 0.83 0.79 -0.11 -0.28 Covered/w/another[1480]
YDR508C GNP1 "High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids" Verified chr4:1466445-1468436 1466445-1468436 97.6% 679.25 672.04 731.22 452.83 625.73 436.36 675.64 592.02 531.05 2.49 2.40 2.20 -0.16 0.23 Frag>80[1479,1480]
YDR510W SMT3 "Ubiquitin-like protein of the SUMO family, conjugated to lysine residues of target proteins; regulates chromatid cohesion, chromosome segregation, APC-mediated proteolysis, DNA replication and septin ring dynamics" Verified chr4:1469392-1469697 1469392-1469697 98.4% 2238.58 2195.41 2065.87 2065.87 2145.59 1727.10 2216.99 2065.87 1936.34 8.18 8.39 8.02 -0.09 -0.38 Matched[1482]
YDR510C-A "Dubious open reading frame unlikely to encode a functional protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr4:1469687-1469803 1469687-1469803 99.6% 1527.90 1665.24 1665.24 1553.65 1656.65 1124.46 1596.57 1609.44 1390.56 5.89 6.53 5.76 -0.21 NaN Matched[1482]
YDR511W ACN9 "Protein of the mitochondrial intermembrane space, required for acetate utilization and gluconeogenesis; has orthologs in higher eukaryotes" Verified chr4:1470009-1470410 1470009-1470410 98.7% 229.36 194.08 335.22 282.29 667.93 388.15 211.72 308.76 528.04 0.78 1.25 2.19 0.77 0.47 Matched[1483]
YDR513W GRX2 "Cytoplasmic glutaredoxin, thioltransferase, glutathione-dependent disulfide oxidoreductase involved in maintaining redox state of target proteins, also exhibits glutathione peroxidase activity, expression induced in response to stress" Verified chr4:1471009-1471440 1471009-1471440 98.8% 1047.25 923.08 1265.13 1159.70 4957.44 2757.52 985.16 1212.42 3857.48 3.64 4.92 15.98 1.67 0.94 Matched[1484]
YDR512C EMI1 "Non-essential protein of unknown function required for transcriptional induction of the early meiotic-specific transcription factor IME1, also required for sporulation" Verified chr4:1470492-1471055 1470492-1471055 99.4% 319.38 246.23 322.95 322.95 1207.94 610.21 282.80 322.95 909.08 1.04 1.31 3.77 1.49 1.09 Frag>80[1483,1484]
YDR514C Putative protein of unknown function Uncharacterized chr4:1471540-1472991 1471540-1472991 99.4% 96.31 71.37 59.59 51.97 20.09 9.01 83.84 55.78 14.55 0.31 0.23 0.06 -1.94 -1.09 Matched[1485]
YDR515W SLF1 RNA binding protein that associates with polysomes; proposed to be involved in regulating mRNA translation; involved in the copper-dependent mineralization of copper sulfide complexes on cell surface in cells cultured in copper salts Verified chr4:1473421-1474764 1473421-1474764 98.9% 91.04 72.23 91.04 93.29 93.29 72.98 81.63 92.17 83.14 0.30 0.37 0.34 -0.15 -0.01 Matched[1486]
YDR516C EMI2 Non-essential protein of unknown function required for transcriptional induction of the early meiotic-specific transcription factor IME1; required for sporulation; expression is regulated by glucose-repression transcription factors Mig1/2p Verified chr4:1474966-1476468 1474966-1476468 99.1% 342.52 728.70 831.45 1031.59 1646.12 1587.69 535.61 931.52 1616.90 1.98 3.78 6.70 0.80 1.25 Frag>80[1487,1488,1489]
YDR517W GRH1 "Acetylated, cis-golgi localized protein involved in ER to Golgi transport; homolog of human GRASP65; forms a complex with the coiled-coil protein Bug1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes" Verified chr4:1477231-1478349 1477231-1478349 98.5% 371.83 427.15 428.05 369.11 559.55 369.11 399.49 398.58 464.33 1.47 1.62 1.92 0.22 0.36 Matched[1490]
YDR518W EUG1 "Protein disulfide isomerase of the endoplasmic reticulum lumen, function overlaps with that of Pdi1p; may interact with nascent polypeptides in the ER" Verified chr4:1478600-1480153 1478600-1480153 99.0% 252.18 334.72 277.53 284.03 246.33 226.83 293.45 280.78 236.58 1.08 1.14 0.98 -0.25 0.54 Matched[1491]
YDR519W FPR2 "Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin; expression pattern suggests possible involvement in ER protein trafficking" Verified chr4:1480417-1480824 1480417-1480824 98.4% 687.49 600.31 754.75 660.09 789.62 440.89 643.90 707.42 615.26 2.38 2.87 2.55 -0.20 -1.06 Matched[1492]
YDR521W Dubious ORF that overlaps YDR520C; mutant increases expression of PIS1 and RPL3 in glycerol Dubious chr4:1483133-1483468 1483133-1483468 99.1% 15.01 21.02 21.02 9.01 21.02 18.01 18.01 15.01 19.51 0.07 0.06 0.08 0.38 -0.06 Covered/w/another[1493]
YDR520C Putative transcription factor; contains the (Zn(II)2Cys6 motif; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is viable and sensitive to caffeine Uncharacterized chr4:1481077-1483395 1481077-1483395 99.2% 61.28 52.15 48.24 37.37 43.89 26.94 56.71 42.81 35.42 0.21 0.17 0.15 -0.27 -0.34 Matched[1493]
YDR522C SPS2 "Protein expressed during sporulation, redundant with Sps22p for organization of the beta-glucan layer of the spore wall; S. pombe ortholog is a spore wall component" Verified chr4:1483787-1485295 1483787-1485295 99.4% 18.00 12.00 15.33 12.00 14.00 9.33 15.00 13.66 11.66 0.06 0.06 0.05 -0.23 0.34
YDR523C SPS1 "Putative protein serine/threonine kinase expressed at the end of meiosis and localized to the prospore membrane, required for correct localization of enzymes involved in spore wall synthesis" Verified chr4:1485558-1487030 1485558-1487030 99.2% 11.63 11.63 6.84 5.47 5.47 4.10 11.63 6.16 4.79 0.04 0.02 0.02 -0.36 -0.29
YDR524C AGE1 "ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector, involved in the secretory and endocytic pathways; contains C2C2H2 cysteine/histidine motif" Verified chr4:1487534-1488982 1487534-1488982 99.1% 179.74 189.49 153.96 119.83 89.17 45.98 184.62 136.89 67.58 0.68 0.56 0.28 -1.02 -1.72 Matched[1494]
YDR524W-C Putative protein of unknown function; small ORF identified by SAGE; deletion strains are moderately sensitive to the radiomimetic drug bleomycin Uncharacterized chr4:1489395-1489484 1489395-1489484 99.3% 35104.48 33324.63 30067.16 28399.25 12011.19 6783.58 34214.55 29233.21 9397.39 126.30 118.66 38.94 -1.64 NaN Matched[1495]
YDR524C-B Putative protein of unknown function Uncharacterized chr4:1489590-1489790 1489590-1489790 97.5% 25678.22 23413.39 23648.03 21107.76 9865.25 5912.01 24545.80 22377.90 7888.63 90.61 90.84 32.69 -1.50 NaN Matched[1495]
YDR525W API2 "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 26% of ORF overlaps the dubious ORF YDR524C-A; insertion mutation in a cdc34-2 mutant background causes altered bud morphology" Dubious chr4:1489897-1490226 1489897-1490226 98.3% 9.25 12.33 0.00 9.25 0.00 3.08 10.79 4.63 1.54 0.04 0.02 0.01 -1.58 -0.50 Frag<80[1495,1496]
YDR524C-A "Dubious open reading frame unlikely to encode a functional protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr4:1489863-1489982 1489863-1489982 98.0% 8.50 8.50 17.01 17.01 0.00 8.50 8.50 17.01 4.25 0.03 0.07 0.02 -2.00 NaN Matched[1495]
YDR525W-A SNA2 "Protein of unknown function, has similarity to Pmp3p, which is involved in cation transport; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" Verified chr4:1490588-1490827 1490588-1490827 99.1% 634.90 639.10 622.28 626.49 769.45 529.78 637.00 624.39 649.61 2.35 2.53 2.69 0.06 -0.23 Matched[1496]
YDR527W RBA50 "Protein involved in transcription; interacts with RNA polymerase II subunits Rpb2p, Rpb3, and Rpb11p; has similarity to human RPAP1" Verified chr4:1491086-1492405 1491086-1492405 98.5% 197.62 196.85 172.25 119.19 83.05 53.83 197.24 145.72 68.44 0.73 0.59 0.28 -1.09 -1.01 Matched[1497]
YDR526C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:1491067-1491537 1491067-1491537 98.2% 151.31 129.69 136.18 88.62 47.55 38.91 140.50 112.40 43.23 0.52 0.46 0.18 -1.38 -0.46 Covered/w/another[1497]
YDR528W HLR1 "Protein involved in regulation of cell wall composition and integrity and response to osmotic stress; overproduction suppresses a lysis sensitive PKC mutation; similar to Lre1p, which functions antagonistically to protein kinase A" Verified chr4:1494578-1495849 1494578-1495849 99.0% 233.54 235.92 195.41 150.93 99.30 54.02 234.73 173.17 76.66 0.87 0.70 0.32 -1.18 -0.53 Matched[1499]
YDR529C QCR7 "Subunit 7 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; oriented facing the mitochondrial matrix; N-terminus appears to play a role in complex assembly" Verified chr4:1496157-1496540 1496157-1496540 98.9% 1021.28 1184.47 1197.63 1360.82 3205.97 2318.93 1102.87 1279.23 2762.45 4.07 5.19 11.45 1.11 -0.44 Matched[1500]
YDR530C APA2 "Diadenosine 5',5''-P1,P4-tetraphosphate phosphorylase II (AP4A phosphorylase), involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; has similarity to Apa1p" Verified chr4:1496783-1497760 1496783-1497760 98.9% 204.76 267.84 221.30 204.76 221.30 138.57 236.30 213.03 179.94 0.87 0.86 0.75 -0.24 -0.20 Frag>80[1501,1502]
YDR531W "Pantothenate kinase (ATP:D-pantothenate 4'-phosphotransferase, EC 2.7.1.33); catalyzes the first committed step in the universal biosynthetic pathway leading to coenzyme A1" Uncharacterized chr4:1498224-1499327 1498224-1499327 99.0% 265.47 320.39 246.24 202.30 199.56 135.48 292.93 224.27 167.52 1.08 0.91 0.69 -0.42 -0.15 Matched[1503]
YDR532C Protein of unknown function that localizes to the nuclear side of the spindle pole body and along short spindles; deletion mutants have short telomeres; forms a complex with Spc105p Uncharacterized chr4:1499388-1500545 1499388-1500545 99.6% 88.41 104.01 84.08 77.14 168.15 130.88 96.21 80.61 149.52 0.36 0.33 0.62 0.89 0.29 Covered[1504]
YDR533C HSP31 "Possible chaperone and cysteine protease with similarity to E. coli Hsp31; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease; exists as a dimer and contains a putative metal-binding site" Verified chr4:1501439-1502152 1501439-1502152 99.0% 182.46 154.17 192.36 144.27 1915.13 1451.20 168.32 168.32 1683.17 0.62 0.68 6.97 3.32 3.09 Matched[1505]
YDR534C FIT1 "Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall" Verified chr4:1503305-1504891 1503305-1504891 72.5% 13.90 18.24 15.64 15.64 9.56 6.08 16.07 15.64 7.82 0.06 0.06 0.03 -1.00 0.10
YDR535C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YDR535C is not an essential gene." Dubious chr4:1506597-1507353 1506597-1507049,1507306-1507353 98.7% 2.02 16.17 2.02 2.02 8.09 2.02 9.10 2.02 5.05 0.03 0.01 0.02 1.32 0.63
YDR536W STL1 "Glycerol proton symporter of the plasma membrane, subject to glucose-induced inactivation, strongly but transiently induced when cells are subjected to osmotic shock" Verified chr4:1507996-1509705 1507996-1509705 98.8% 17.16 18.35 15.39 5.92 27.22 17.75 17.75 10.65 22.49 0.07 0.04 0.09 1.08 1.33 Frag<80[1506]
YDR538W PAD1 "Phenylacrylic acid decarboxylase, confers resistance to cinnamic acid, decarboxylates aromatic carboxylic acids to the corresponding vinyl derivatives; homolog of E. coli UbiX" Verified chr4:1510892-1511620 1510892-1511620 98.8% 168.00 151.34 168.00 144.39 131.90 77.75 159.67 156.20 104.82 0.59 0.63 0.43 -0.58 -0.19 Matched[1508]
YDR537C "Dubious open reading frame unlikely to encode a protein, almost completely overlaps verified ORF PAD1/YDR538W" Dubious chr4:1510846-1511451 1510846-1511451 98.8% 141.94 145.28 153.63 128.58 125.24 65.13 143.61 141.11 95.19 0.53 0.57 0.39 -0.57 -0.01 Matched[1508]
YDR539W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YDR539W is not an essential gene; homolog of E. coli UbiD Uncharacterized chr4:1512084-1513595 1512084-1513595 98.7% 184.97 203.73 184.30 188.99 142.75 145.43 194.35 186.64 144.09 0.72 0.76 0.60 -0.37 0.03 Matched[1509]
YDR540C Hypothetical protein; null mutant displays increased levels of spontaneous Rad52 foci Uncharacterized chr4:1517120-1517659 1517120-1517659 99.3% 59.65 39.15 61.51 44.74 274.02 147.26 49.40 53.13 210.64 0.18 0.22 0.87 1.99 1.95 Covered/w/another[1512]
YDR541C Putative dihydrokaempferol 4-reductase Uncharacterized chr4:1519648-1520682 1519648-1520682 98.9% 128.02 151.48 103.59 111.41 148.55 90.89 139.75 107.50 119.72 0.52 0.44 0.50 0.16 0.36 Covered/w/another[1512]
YDR542W Hypothetical protein Uncharacterized chr4:1523234-1523596 1523234-1523596 0.7% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.28
YDR543C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:1524619-1524918 1524619-1524918 5.2% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN -0.32
YDR544C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr4:1525080-1525508 1525080-1525508 47.7% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 1.15
YDR545W YRF1-1 "Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p" Verified chr4:1526306-1531696 1526306-1531696 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.31
YDR545C-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr4:1530848-1531327 1530848-1531327 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YEL077W-A "Dubious open reading frame, unlike to encode a functional protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr5:630-1112 630-1112 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YEL077C Helicase-like protein encoded within the telomeric Y' element Uncharacterized chr5:264-4097 264-4097 2.9% 98.36 80.48 62.59 17.88 35.77 26.83 89.42 40.24 31.30 0.33 0.16 0.13 -0.36 -0.15 Frag<80[1514]
YEL075W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr5:4870-5481 4870-5481 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.25
YEL076C Putative protein of unknown function Uncharacterized chr5:4464-5114 4464-5114 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.47
YEL076C-A Putative protein of unknown function Uncharacterized chr5:4185-5114 4185-4322,4602-5114 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.40
YEL075C Putative protein of unknown function Uncharacterized chr5:5345-5713 5345-5713 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.18
YEL074W Hypothetical protein Dubious chr5:6126-6464 6126-6464 42.7% 34.55 20.73 13.82 41.46 6.91 0.00 27.64 27.64 3.46 0.10 0.11 0.01 -3.00 -0.62 Frag<80[1515]
YEL073C Putative protein of unknown function; located adjacent to ARS503 and the telomere on the left arm of chromosome V; regulated by inositol/choline Uncharacterized chr5:7230-7553 7230-7553 68.5% 27.03 36.04 49.56 22.53 225.27 184.72 31.54 36.04 204.99 0.12 0.15 0.85 2.51 0.95 Matched[1516]
YEL072W RMD6 Protein required for sporulation Verified chr5:13720-14415 13720-14415 99.0% 65.33 81.30 74.04 49.36 126.30 50.81 73.31 61.70 88.56 0.27 0.25 0.37 0.52 0.59 Matched[1520]
YEL071W DLD3 "D-lactate dehydrogenase, part of the retrograde regulon which consists of genes whose expression is stimulated by damage to mitochondria and reduced in cells grown with glutamate as the sole nitrogen source, located in the cytoplasm" Verified chr5:16355-17845 16355-17845 98.7% 739.49 1405.57 833.28 657.25 799.30 602.87 1072.53 745.26 701.08 3.96 3.03 2.90 -0.09 0.37 Matched[1522]
YEL070W DSF1 Deletion suppressor of mpt5 mutation Uncharacterized chr5:19589-21097 19589-21097 7.0% 9.48 0.00 9.48 0.00 9.48 28.45 4.74 4.74 18.96 0.02 0.02 0.08 2.00 0.66
YEL069C HXT13 "Hexose transporter, induced in the presence of non-fermentable carbon sources, induced by low levels of glucose, repressed by high levels of glucose" Verified chr5:21537-23231 21537-23231 19.3% 27.48 12.21 12.21 3.05 18.32 24.43 19.85 7.63 21.37 0.07 0.03 0.09 1.49 0.93 Frag<80[1523]
YEL068C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr5:25646-25978 25646-25978 99.0% 227.39 245.58 215.26 145.53 236.48 166.75 236.48 180.39 201.62 0.87 0.73 0.84 0.16 0.31 Matched[1525]
YEL066W HPA3 "D-Amino acid N-acetyltransferase, catalyzes N-acetylation of D-amino acids through ordered bi-bi mechanism in which acetyl-CoA is first substrate bound and CoA is last product liberated; similar to Hpa2p, acetylates histones weakly in vitro" Verified chr5:26667-27206 26667-27206 98.2% 148.95 126.33 113.13 126.33 186.66 131.98 137.64 119.73 159.32 0.51 0.49 0.66 0.41 0.42 Matched[1527]
YEL067C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr5:26189-26776 26189-26776 98.4% 43.19 50.10 50.10 50.10 46.64 46.64 46.64 50.10 46.64 0.17 0.20 0.19 -0.10 -0.41 Matched[1526]
YEL065W SIT1 "Ferrioxamine B transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; transcription is induced during iron deprivation and diauxic shift; potentially phosphorylated by Cdc28p" Verified chr5:27657-29543 27657-29543 98.9% 346.06 87.85 253.92 136.07 78.21 53.57 216.95 194.99 65.89 0.80 0.79 0.27 -1.57 -0.67 Matched[1528]
YEL064C AVT2 "Putative transporter, member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters" Verified chr5:29797-31239 29797-31239 99.1% 67.85 81.84 62.25 71.35 67.15 38.47 74.84 66.80 52.81 0.28 0.27 0.22 -0.34 -0.28 Matched[1529]
YEL063C CAN1 "Plasma membrane arginine permease, requires phosphatidyl ethanolamine (PE) for localization, exclusively associated with lipid rafts; mutation confers canavanine resistance" Verified chr5:31694-33466 31694-33466 98.8% 242.69 300.94 247.83 204.43 121.06 93.08 271.81 226.13 107.07 1.00 0.92 0.44 -1.08 1.19 Covered/w/another[1530]
YEL062W NPR2 Protein with a possible role in regulating expression of nitrogen permeases; transcription is induced in response to proline and urea; contains two PEST sequences; null mutant is resistant to cisplatin and doxorubicin Verified chr5:34407-36254 34407-36254 99.1% 57.34 67.17 63.35 52.43 112.50 108.13 62.26 57.89 110.32 0.23 0.23 0.46 0.93 0.70 Covered/w/another[1530]
YEL061C CIN8 Kinesin motor protein involved in mitotic spindle assembly and chromosome segregation Verified chr5:36535-39537 36535-39537 99.4% 134.36 132.02 115.27 100.52 78.41 71.04 133.19 107.89 74.72 0.49 0.44 0.31 -0.53 -0.24 Covered/w/another[1530]
YEL060C PRB1 "Vacuolar proteinase B (yscB), a serine protease of the subtilisin family; involved in protein degradation in the vacuole and required for full protein degradation during sporulation" Verified chr5:40046-41953 40046-41953 98.6% 384.22 627.08 596.25 577.12 1724.99 2157.03 505.65 586.69 1941.01 1.87 2.38 8.04 1.73 2.27 Frag>80[1531,1532]
YEL059C-A SOM1 "Subunit of the mitochondrial inner membrane peptidase, which is required for maturation of mitochondrial proteins of the intermembrane space; Som1p facilitates cleavage of a subset of substrates" Verified chr5:42400-42624 42400-42624 98.1% 163.08 135.90 126.84 154.02 140.43 126.84 149.49 140.43 133.64 0.55 0.57 0.55 -0.07 0.05 Matched[1533]
YEL059W Dubious open reading frame unlikely to encode a functional protein Dubious chr5:42652-42960 42652-42960 99.0% 42.48 32.68 39.21 26.14 32.68 16.34 37.58 32.68 24.51 0.14 0.13 0.10 -0.42 1.77 Frag>80[1533,1534]
YEL058W PCM1 "Essential N-acetylglucosamine-phosphate mutase; converts GlcNAc-6-P to GlcNAc-1-P, which is a precursor for the biosynthesis of chitin and for the formation of N-glycosylated mannoproteins and glycosylphosphatidylinositol anchors" Verified chr5:43252-44925 43252-44925 98.6% 434.53 329.69 377.57 360.60 263.02 260.60 382.11 369.08 261.81 1.41 1.50 1.08 -0.50 0.00 Matched[1535]
YEL057C Protein of unknown function involved in telomere maintenance; target of UME6 regulation Uncharacterized chr5:45020-45721 45020-45721 99.2% 5.75 7.18 14.36 11.49 57.45 22.98 6.46 12.93 40.22 0.02 0.05 0.17 1.64 1.84 Matched[1536]
YEL056W HAT2 "Subunit of the Hat1p-Hat2p histone acetyltransferase complex; required for high affinity binding of the complex to free histone H4, thereby enhancing Hat1p activity; similar to human RbAp46 and 48; has a role in telomeric silencing" Verified chr5:47168-48373 47168-48373 98.7% 172.15 183.91 179.71 172.99 205.75 145.28 178.03 176.35 175.51 0.66 0.72 0.73 -0.01 0.13 Matched[1537]
YEL055C POL5 "DNA Polymerase phi; has sequence similarity to the human MybBP1A and weak sequence similarity to B-type DNA polymerases, not required for chromosomal DNA replication; required for the synthesis of rRNA" Verified chr5:48471-51539 48471-51539 99.2% 214.87 150.80 153.76 121.24 42.71 31.87 182.84 137.50 37.29 0.67 0.56 0.15 -1.88 -1.66 Frag>80[1538]
YEL053W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YEL054C" Dubious chr5:52908-53255 52908-53255 86.1% 5640.18 4184.22 4945.60 3830.25 634.48 360.65 4912.20 4387.92 497.57 18.13 17.81 2.06 -3.14 NaN Matched[1540]
YEL054C RPL12A "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Bp; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins" Verified chr5:52721-53218 52721-53218 77.3% 6302.53 4596.41 5227.44 4027.70 734.91 360.96 5449.47 4627.57 547.93 20.12 18.78 2.27 -3.08 -3.61 Matched[1540]
YEL053C MAK10 "Non-catalytic subunit of N-terminal acetyltransferase of the NatC type, required for replication of dsRNA virus; expression is glucose-repressible" Verified chr5:53901-56102 53901-56102 99.2% 156.98 135.01 107.09 93.36 31.12 20.14 145.99 100.23 25.63 0.54 0.41 0.11 -1.97 -1.44 Matched[1541]
YEL052W AFG1 Conserved protein that may act as a chaperone in the degradation of misfolded or unassembled cytochrome c oxidase subunits; localized to matrix face of the mitochondrial inner membrane; member of the AAA family but lacks a protease domain Verified chr5:56571-58100 56571-58100 98.7% 246.99 262.22 241.70 277.45 232.42 203.95 254.61 259.57 218.19 0.94 1.05 0.90 -0.25 0.10 Matched[1542]
YEL051W VMA8 "Subunit D of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; plays a role in the coupling of proton transport and ATP hydrolysis" Verified chr5:58378-59148 58378-59148 98.4% 1527.09 1926.32 1592.97 1574.53 1328.14 1150.26 1726.71 1583.75 1239.20 6.37 6.43 5.13 -0.35 -0.73 Matched[1543]
YEL050W-A "Dubious open reading frame unlikely to encode a functional protein, identified by fungal homology and RT-PCR" Dubious chr5:59549-59740 59549-59740 99.5% 277.43 324.54 324.54 293.13 450.16 198.91 300.98 308.83 324.54 1.11 1.25 1.34 0.07 NaN Covered/w/another[1545]
YEL050C RML2 "Mitochondrial ribosomal protein of the large subunit, has similarity to E. coli L2 ribosomal protein; fat21 mutant allele causes inability to utilize oleate and may interfere with activity of the Adr1p transcription factor" Verified chr5:59670-60851 59670-60851 98.9% 259.92 302.67 264.20 273.60 348.84 257.36 281.30 268.90 303.10 1.04 1.09 1.26 0.17 0.11 Matched[1545]
YEL049W PAU2 "Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme" Verified chr5:63728-64090 63728-64090 24.9% 11.05 11.05 22.11 0.00 22.11 0.00 11.05 11.05 11.05 0.04 0.04 0.05 0.00 0.89
YEL048C Putative protein of unknown function; synthetic lethal with gcs1delta Uncharacterized chr5:64709-65167 64709-65167 99.4% 94.25 87.67 74.52 56.99 15.34 24.11 90.96 65.75 19.73 0.34 0.27 0.08 -1.74 -2.00 Matched[1547]
YEL047C "Soluble fumarate reductase, required with isoenzyme Osm1p for anaerobic growth; may interact with ribosomes, based on co-purification experiments; authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies" Verified chr5:65385-66797 65385-66797 98.8% 417.41 860.59 439.61 388.77 479.70 424.57 639.00 414.19 452.13 2.36 1.68 1.87 0.13 0.67 Frag>80[1548,1549,1550]
YEL046C GLY1 "Threonine aldolase, catalyzes the cleavage of L-allo-threonine and L-threonine to glycine; involved in glycine biosynthesis" Verified chr5:67629-68792 67629-68792 98.5% 727.99 877.94 560.59 447.25 176.11 143.85 802.96 503.92 159.98 2.96 2.05 0.66 -1.66 -0.99 Matched[1551]
YEL045C "Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; deletion gives MMS sensitivity, growth defect under alkaline conditions, less than optimal growth upon citric acid stress" Dubious chr5:68840-69265 68840-69265 97.6% 69.74 67.33 48.10 38.48 16.83 12.02 68.54 43.29 14.43 0.25 0.18 0.06 -1.58 -0.27 Overlap[1551,1552]
YEL044W IES6 Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions Verified chr5:69757-70257 69757-70257 98.1% 282.71 276.61 246.10 195.25 252.20 115.93 279.66 220.68 184.07 1.03 0.90 0.76 -0.26 -0.64 Covered/w/another[1552]
YEL043W "Predicted cytoskeleton protein involved in intracellular signalling based on quantitative analysis of protein-protein interaction maps; may interact with ribosomes, based on co-purification studies; contains fibronectin type III domain fold" Verified chr5:70478-73348 70478-73348 99.0% 147.45 169.97 140.76 124.93 73.55 133.02 158.71 132.84 103.28 0.59 0.54 0.43 -0.36 0.72 Covered/w/another[1552]
YEL042W GDA1 "Guanosine diphosphatase located in the Golgi, involved in the transport of GDP-mannose into the Golgi lumen by converting GDP to GMP after mannose is transferred its substrate" Verified chr5:73771-75327 73771-75327 98.8% 385.30 320.98 422.34 389.85 142.30 93.56 353.14 406.10 117.93 1.30 1.65 0.49 -1.78 -1.30 Covered/w/another[1552]
YEL041W YEF1 ATP-NADH kinase; phosophorylates both NAD and NADH; homooctameric structure consisting of 60-kDa subunits; sequence similarity to Utr1p and Pos5p; overexpression complements certain pos5 phenotypes Verified chr5:75944-77431 75944-77431 98.7% 31.32 37.45 39.49 26.56 122.57 82.39 34.39 33.03 102.48 0.13 0.13 0.42 1.63 2.27 Covered/w/another[1552]
YEL040W UTR2 Cell wall protein that functions in the transfer of chitin to beta(1-6)glucan; putative chitin transglycosidase; glycosylphosphatidylinositol (GPI)-anchored protein localized to the bud neck; has a role in cell wall maintenance Verified chr5:78053-79456 78053-79456 98.0% 1495.68 1160.48 1142.30 1015.78 173.05 124.34 1328.08 1079.04 148.70 4.90 4.38 0.62 -2.86 -1.30 Frag>80[1553]
YEL039C CYC7 "Cytochrome c isoform 2, expressed under hypoxic conditions; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration" Verified chr5:79636-79977 79636-79977 93.5% 134.43 296.99 347.01 343.88 7768.66 4776.87 215.71 345.45 6272.76 0.80 1.40 25.99 4.18 2.47 Covered/w/another[1553]
YEL038W UTR4 "Protein of unknown function with sequence similarity to 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatases, found in both the cytoplasm and nucleus" Verified chr5:80462-81145 80462-81145 98.4% 353.68 352.20 371.52 304.64 573.62 371.52 352.94 338.08 472.57 1.30 1.37 1.96 0.48 0.52 Frag>80[1554,1555]
YEL037C RAD23 "Protein with ubiquitin-like N terminus, recognizes and binds damaged DNA (with Rad4p) during nucleotide excision repair; regulates Rad4p levels, subunit of Nuclear Excision Repair Factor 2 (NEF2); homolog of human HR23A and HR23B proteins" Verified chr5:81407-82603 81407-82603 98.8% 495.46 367.79 523.36 494.61 476.01 344.96 431.62 508.98 410.48 1.59 2.07 1.70 -0.31 -0.01 Matched[1556]
YEL036C ANP1 "Subunit of the alpha-1,6 mannosyltransferase complex; type II membrane protein; has a role in retention of glycosyltransferases in the Golgi; involved in osmotic sensitivity and resistance to aminonitrophenyl propanediol" Verified chr5:83050-84552 83050-84552 96.3% 330.12 296.97 337.72 281.09 133.98 125.00 313.54 309.40 129.49 1.16 1.26 0.54 -1.26 -0.54 Matched[1557]
YEL035C UTR5 Protein of unknown function; transcription may be regulated by Gcr1p Uncharacterized chr5:85045-85545 85045-85545 98.4% 4.06 6.09 2.03 2.03 16.23 10.14 5.07 2.03 13.18 0.02 0.01 0.05 2.70 0.56 Overlap[1558]
YEL034W HYP2 "Translation initiation factor eIF-5A, promotes formation of the first peptide bond; similar to and functionally redundant with Anb1p; possible role in translation elongation; undergoes an essential hypusination modification" Verified chr5:85676-86149 85676-86149 78.4% 8440.36 6578.48 8698.65 7617.04 10191.93 6075.34 7509.42 8157.85 8133.63 27.72 33.11 33.70 -0.00 -1.32 Matched[1558]
YEL033W "Predicted to have metabolic role based on analysis of gene networks derived from chromatin immunoprecipitation experiments, experiments on gene deletion mutants, and localization of transcription factor binding sites" Dubious chr5:86179-86598 86179-86598 97.7% 2829.69 2371.48 2944.25 2710.27 3448.77 1857.22 2600.59 2827.26 2652.99 9.60 11.48 10.99 -0.09 0.18 Frag<80[1558]
YEL034C-A "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; completely overlaps HYP2/YEL034W, a verified gene that encodes eiF-5A" Dubious chr5:85613-86215 85613-86215 82.8% 8328.41 6642.30 8684.86 7685.61 10162.70 6051.56 7485.36 8185.23 8107.13 27.63 33.23 33.59 -0.01 NaN Matched[1558]
YEL032W MCM3 Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex Verified chr5:86937-89852 86937-89852 98.6% 156.52 158.61 153.74 117.22 52.52 52.17 157.57 135.48 52.35 0.58 0.55 0.22 -1.37 -0.69 Matched[1559]
YEL032C-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr5:87040-87201 87040-87201 98.2% 113.18 100.60 62.88 25.15 25.15 44.01 106.89 44.01 34.58 0.39 0.18 0.14 -0.35 NaN Covered/w/another[1559]
YEL031W SPF1 "P-type ATPase, ion transporter of the ER membrane involved in ER function and Ca2+ homeostasis; required for regulating Hmg2p degradation; confers sensitivity to a killer toxin (SMKT) produced by Pichia farinosa KK1" Verified chr5:90258-93905 90258-93905 99.0% 489.17 405.80 420.76 383.64 209.69 208.30 447.49 402.20 208.99 1.65 1.63 0.87 -0.94 -0.40 Matched[1560]
YEL030W ECM10 "Heat shock protein of the Hsp70 family, localized in mitochondrial nucleoids, plays a role in protein translocation, interacts with Mge1p in an ATP-dependent manner; overexpression induces extensive mitochondrial DNA aggregations" Verified chr5:94644-96578 94644-96578 98.1% 31.60 56.35 29.49 29.49 46.87 30.54 43.97 29.49 38.71 0.16 0.12 0.16 0.39 0.91 Covered/w/another[1561]
YEL030C-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr5:94583-94897 94583-94897 99.0% 22.45 48.10 19.24 19.24 16.03 19.24 35.28 19.24 17.64 0.13 0.08 0.07 -0.13 NaN Covered/w/another[1561]
YEL029C BUD16 Protein involved in bud-site selection and telomere maintenance; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern; has similarity to pyridoxal kinases Verified chr5:96858-97796 96858-97796 99.1% 132.17 161.18 107.45 99.93 55.88 34.39 146.68 103.69 45.13 0.54 0.42 0.19 -1.20 -0.83 Covered/w/another[1561]
YEL028W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr5:98668-99129 98668-99129 99.0% 74.34 61.22 19.68 8.75 13.12 15.31 67.78 14.21 14.21 0.25 0.06 0.06 0.00 -0.75 Overlap[1561]
YEL027W CUP5 Proteolipid subunit of the vacuolar H(+)-ATPase V0 sector (subunit c; dicyclohexylcarbodiimide binding subunit); required for vacuolar acidification and important for copper and iron metal ion homeostasis Verified chr5:100769-101251 100769-101251 99.1% 5273.90 5971.79 4835.10 5090.02 3807.07 2647.40 5622.85 4962.56 3227.23 20.76 20.14 13.37 -0.62 -0.93 Matched[1562]
YEL026W SNU13 "RNA binding protein, part of U3 snoRNP involved in rRNA processing, part of U4/U6-U5 tri-snRNP involved in mRNA splicing, similar to human 15.5K protein" Verified chr5:101943-102323 101943-102323 99.1% 2074.40 1261.07 1494.20 1356.44 190.75 79.48 1667.73 1425.32 135.11 6.16 5.79 0.56 -3.40 -2.26 Matched[1563]
YEL025C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus Uncharacterized chr5:102581-106147 102581-106147 99.1% 82.03 100.98 78.35 74.11 83.72 87.40 91.50 76.23 85.56 0.34 0.31 0.35 0.17 0.32 Matched[1564]
YEL024W RIP1 "Ubiquinol-cytochrome-c reductase, a Rieske iron-sulfur protein of the mitochondrial cytochrome bc1 complex; transfers electrons from ubiquinol to cytochrome c1 during respiration" Verified chr5:107260-107907 107260-107907 98.8% 268.56 398.15 424.70 484.03 716.67 521.50 333.36 454.36 619.09 1.23 1.84 2.57 0.45 0.41 Matched[1566]
YEL023C Putative protein of unknown function; expression is increased greatly during sporulation; YEL023C is not an essential gene Uncharacterized chr5:108504-110552 108504-110552 99.3% 63.92 73.75 47.69 50.15 35.89 39.33 68.84 48.92 37.61 0.25 0.20 0.16 -0.38 -0.23 Matched[1567]
YEL022W GEA2 "Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; similar to but not functionally redundant with Gea1p" Verified chr5:111421-115800 111421-115800 98.9% 164.30 132.22 126.68 126.92 54.92 52.15 148.26 126.80 53.54 0.55 0.51 0.22 -1.24 -0.77 Matched[1568]
YEL021W URA3 "Orotidine-5'-phosphate (OMP) decarboxylase, catalyzes the sixth enzymatic step in the de novo biosynthesis of pyrimidines, converting OMP into uridine monophosphate (UMP); converts 5-FOA into 5-fluorouracil, a toxic compound" Verified chr5:116167-116970 116167-116970 98.3% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN -0.09
YEL020W-A TIM9 "Mitochondrial intermembrane space protein, forms a complex with Mrs11p/Tim10p that mediates import and insertion of a subset of polytopic inner membrane proteins; may prevent aggregation of incoming proteins in a chaperone-like manner" Verified chr5:117211-117474 117211-117474 98.3% 427.81 312.19 393.13 393.13 836.36 528.02 370.00 393.13 682.19 1.37 1.60 2.83 0.80 0.03 Matched[1569]
YEL020C-B Dubious open reading frame unlikely to encode a protein; partially overlaps verified gene YEL020W-A; identified by fungal homology and RT-PCR Dubious chr5:117183-117380 117183-117380 98.5% 369.07 312.69 348.57 328.06 779.15 512.60 340.88 338.32 645.88 1.26 1.37 2.68 0.93 NaN Matched[1569]
YEL020C Hypothetical protein with low sequence identity to Pdc1p Uncharacterized chr5:118617-120299 118617-120299 98.8% 76.97 81.78 55.32 71.56 164.16 159.95 79.37 63.44 162.05 0.29 0.26 0.67 1.35 1.60 Covered/w/another[1571]
YEL019C MMS21 SUMO ligase involved in chromosomal organization and DNA repair; essential subunit of the Mms21-Smc5-Smc6 complex; mutants are sensitive to methyl methanesulfonate and show increased spontaneous mutation and mitotic recombination Verified chr5:120498-121301 120498-121301 98.9% 33.94 31.43 27.66 27.66 22.63 31.43 32.68 27.66 27.03 0.12 0.11 0.11 -0.03 0.83 Covered/w/another[1571]
YEL018W EAF5 "Esa1p-associated factor, non-essential subunit of the NuA4 acetyltransferase complex" Verified chr5:121471-122310 121471-122310 98.2% 151.51 136.96 113.93 105.45 80.00 77.57 144.24 109.69 78.78 0.53 0.45 0.33 -0.48 -0.30 Matched[1572]
YEL018C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr5:121455-121988 121455-121988 98.3% 133.39 121.95 104.80 100.99 81.94 76.22 127.67 102.90 79.08 0.47 0.42 0.33 -0.38 NaN Matched[1572]
YEL017C-A PMP2 Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p); regulates plasma membrane H(+)-ATPase activity; nearly identical to PMP1 Verified chr5:122798-122929 122798-122929 85.0% 4587.97 4890.87 3438.75 3020.04 3153.68 2191.54 4739.42 3229.40 2672.61 17.50 13.11 11.07 -0.27 -0.62 Matched[1573]
YEL017W GTT3 "Protein of unknown function with a possible role in glutathione metabolism, as suggested by computational analysis of large-scale protein-protein interaction data; GFP-fusion protein localizes to the nuclear periphery" Verified chr5:123657-124670 123657-124670 98.8% 271.55 277.54 233.61 196.67 332.45 207.65 274.54 215.14 270.05 1.01 0.87 1.12 0.33 0.56 Matched[1575]
YEL016C NPP2 Nucleotide pyrophosphatase/phosphodiesterase family member; mediates extracellular nucleotide phosphate hydrolysis along with Npp1p and Pho5p; activity and expression enhanced during conditions of phosphate starvation Verified chr5:124737-126218 124737-126218 99.1% 132.77 170.21 113.02 100.09 90.55 59.23 151.49 106.55 74.89 0.56 0.43 0.31 -0.51 -0.33 Matched[1576]
YEL015W EDC3 "Non-essential conserved protein of unknown function, plays a role in mRNA decapping by specifically affecting the function of the decapping enzyme Dcp1p; localizes to cytoplasmic mRNA processing bodies" Verified chr5:126629-128284 126629-128284 98.7% 220.85 209.83 205.55 178.02 165.79 116.85 215.34 191.79 141.32 0.79 0.78 0.59 -0.44 -0.17 Matched[1577]
YEL014C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr5:128303-128608 128303-128608 98.7% 82.79 66.23 92.73 62.92 105.97 72.86 74.51 77.83 89.42 0.28 0.32 0.37 0.20 -0.01
YEL013W VAC8 "Phosphorylated vacuolar membrane protein that interacts with Atg13p, required for the cytoplasm-to-vacuole targeting (Cvt) pathway; interacts with Nvj1p to form nucleus-vacuole junctions" Verified chr5:128825-130561 128825-130561 98.8% 336.14 404.30 364.10 346.63 482.37 338.47 370.22 355.37 410.42 1.37 1.44 1.70 0.21 0.48 Matched[1578]
YEL012W UBC8 "Ubiquitin-conjugating enzyme that negatively regulates gluconeogenesis by mediating the glucose-induced ubiquitination of fructose-1,6-bisphosphatase (FBPase); cytoplasmic enzyme that catalyzes the ubiquitination of histones in vitro" Verified chr5:131772-132551 131772-131776,131900-132551 98.5% 168.51 213.35 190.16 207.16 517.91 293.74 190.93 198.66 405.82 0.70 0.81 1.68 1.03 0.62 Matched[1579]
YEL011W GLC3 "Glycogen branching enzyme, involved in glycogen accumulation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" Verified chr5:133120-135234 133120-135234 98.8% 210.11 523.12 610.71 856.24 1699.55 1509.06 366.62 733.47 1604.31 1.35 2.98 6.65 1.13 1.30 Matched[1580]
YEL010W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr5:136279-136629 136279-136629 98.8% 0.00 8.65 2.88 2.88 8.65 8.65 4.33 2.88 8.65 0.02 0.01 0.04 1.58 0.02
YEL009C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr5:136371-136778 136371-136778 98.5% 2.49 9.95 2.49 2.49 9.95 12.44 6.22 2.49 11.20 0.02 0.01 0.05 2.17 NaN
YEL009C GCN4 Transcriptional activator of amino acid biosynthetic genes in response to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels Verified chr5:138918-139763 138918-139763 98.8% 6110.35 6390.27 5238.30 4886.61 2173.55 1379.26 6250.31 5062.45 1776.40 23.07 20.55 7.36 -1.51 -1.65 Frag>80[1582,1583,1584]
YEL008W Hypothetical protein predicted to be involved in metabolism Dubious chr5:140512-140892 140512-140892 98.2% 26.74 34.76 13.37 13.37 13.37 40.11 30.75 13.37 26.74 0.11 0.05 0.11 1.00 0.25 Matched[1585]
YEL008C-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr5:140726-140818 140726-140818 98.5% 32.74 21.83 10.91 0.00 0.00 10.91 27.29 5.46 5.46 0.10 0.02 0.02 0.00 NaN Matched[1585]
YEL007W Putative protein with sequence similarity to S. pombe gti1+ (gluconate transport inducer 1) Uncharacterized chr5:141891-143891 141891-143891 96.6% 338.33 353.85 401.97 293.84 450.59 385.93 346.09 347.90 418.26 1.28 1.41 1.73 0.27 0.98 Matched[1586]
YEL006W YEA6 "Putative mitochondrial NAD+ transporter, member of the mitochondrial carrier subfamily (see also YIA6); has putative human ortholog" Verified chr5:144326-145333 144326-145333 99.1% 179.25 185.25 186.26 130.18 164.23 113.16 182.25 158.22 138.69 0.67 0.64 0.57 -0.19 0.15 Covered/w/another[1587]
YEL005C VAB2 "Protein with a potential role in vacuolar function, as suggested by its ability to bind Vac8p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" Verified chr5:145906-146754 145906-146754 99.1% 93.85 115.24 89.10 97.42 234.04 166.32 104.54 93.26 200.18 0.39 0.38 0.83 1.10 1.19 Covered/w/another[1587]
YEL004W YEA4 Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter required for cell wall chitin synthesis; localized to the ER Verified chr5:146950-147978 146950-147978 99.2% 120.55 127.41 97.03 87.23 110.75 112.71 123.98 92.13 111.73 0.46 0.37 0.46 0.28 0.42 Covered/w/another[1587]
YEL003W GIM4 Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it Verified chr5:148175-148598 148175-148193,148282-148598 98.8% 725.99 433.79 451.86 418.73 385.59 192.80 579.89 435.30 289.19 2.14 1.77 1.20 -0.59 -0.89 Frag<80[1588]
YEL002C WBP1 Beta subunit of the oligosaccharyl transferase (OST) glycoprotein complex; required for N-linked glycosylation of proteins in the endoplasmic reticulum Verified chr5:148721-150013 148721-150013 98.9% 815.12 761.93 748.63 758.02 519.43 449.02 788.53 753.32 484.22 2.91 3.06 2.01 -0.64 -0.40 Matched[1589]
YEL001C Putative protein of unknown function; green fluorescent protein (GFP)-fusion localizes to the ER; YEL001C is non-essential; null mutant displays increased levels of spontaneous Rad52 foci Uncharacterized chr5:150300-150977 150300-150977 98.9% 925.66 953.98 916.71 822.81 550.03 481.46 939.82 869.76 515.74 3.47 3.53 2.14 -0.75 -0.51 Frag>80[1590,1591]
YER001W MNN1 "Alpha-1,3-mannosyltransferase, integral membrane glycoprotein of the Golgi complex, required for addition of alpha1,3-mannose linkages to N-linked and O-linked oligosaccharides, one of five S. cerevisiae proteins of the MNN1 family" Verified chr5:153519-155807 153519-155807 98.9% 246.58 158.20 182.94 133.89 42.86 30.05 202.39 158.42 36.46 0.75 0.64 0.15 -2.12 -1.87 Covered[1593]
YER002W NOP16 "Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis" Verified chr5:156802-157497 156802-157497 98.0% 477.86 310.76 370.85 262.38 86.48 54.24 394.31 316.62 70.36 1.46 1.29 0.29 -2.17 -2.06 Matched[1594]
YER003C PMI40 "Mannose-6-phosphate isomerase, catalyzes the interconversion of fructose-6-P and mannose-6-P; required for early steps in protein mannosylation" Verified chr5:157735-159117 157735-158993,159087-159117 98.9% 977.03 649.26 899.40 818.64 517.53 440.68 813.15 859.02 479.11 3.00 3.49 1.99 -0.84 -0.28 Matched[1595]
YER004W "Protein of unknown function, localized to the mitochondrial outer membrane" Verified chr5:159579-160274 159579-160274 98.4% 446.96 344.71 464.49 479.09 544.82 464.49 395.84 471.79 504.66 1.46 1.92 2.09 0.10 0.52 Matched[1596]
YER005W YND1 "Apyrase with wide substrate specificity, involved in preventing the inhibition of glycosylation by hydrolyzing nucleoside tri- and diphosphates which are inhibitors of glycotransferases; partially redundant with Gda1p" Verified chr5:160549-162441 160549-162441 98.7% 110.31 128.51 96.39 83.00 121.02 99.06 119.41 89.69 110.04 0.44 0.36 0.46 0.29 0.70 Matched[1597]
YER006W NUG1 "GTPase that associates with nuclear 60S pre-ribosomes, required for export of 60S ribosomal subunits from the nucleus" Verified chr5:162722-164284 162722-164284 98.5% 421.38 164.92 273.35 239.58 33.76 13.63 293.15 256.47 23.70 1.08 1.04 0.10 -3.44 -2.96 Matched[1598]
YER007W PAC2 "Microtubule effector required for tubulin heterodimer formation, binds alpha-tubulin, required for normal microtubule function, null mutant exhibits cold-sensitive microtubules and sensitivity to benomyl" Verified chr5:164526-166082 164526-166082 98.9% 46.12 40.27 27.93 25.98 40.27 24.04 43.20 26.96 32.16 0.16 0.11 0.13 0.25 -0.13 Matched[1599]
YER006C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF PAC2" Dubious chr5:164343-164660 164343-164660 98.9% 34.98 22.26 12.72 6.36 15.90 9.54 28.62 9.54 12.72 0.11 0.04 0.05 0.42 NaN Overlap[1598,1599]
YER007C-A TMA20 Protein of unknown function that associates with ribosomes and has a putative RNA binding domain; interacts with Tma22p; null mutant exhibits translation defects; has homology to human oncogene MCT-1 Verified chr5:166236-166884 166236-166770,166874-166884 99.1% 630.27 454.68 532.31 532.31 449.13 360.42 542.47 532.31 404.77 2.00 2.16 1.68 -0.40 -0.31 Frag>80[1600,1601]
YER008C SEC3 "Non-essential subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, Exo84p) which mediates targeting of post-Golgi vesicles to sites of active exocytosis; Sec3p specifically is a spatial landmark for secretion" Verified chr5:167807-171817 167807-171817 99.2% 131.42 163.84 118.61 131.92 117.35 163.84 147.63 125.26 140.59 0.54 0.51 0.58 0.17 0.64 Matched[1603]
YER009W NTF2 "Nuclear envelope protein, interacts with GDP-bound Gsp1p and with proteins of the nuclear pore to transport Gsp1p into the nucleus where it is an essential player in nucleocytoplasmic transport" Verified chr5:172114-172491 172114-172491 99.2% 2625.46 2230.57 2350.64 2481.38 1766.31 1603.56 2428.02 2416.01 1684.94 8.96 9.81 6.98 -0.52 -0.48 Matched[1604]
YER010C "Protein of unknown function, forms a ring-shaped homotrimer; has similarity to members of the prokaryotic rraA family; possibly involved in a phosphotransfer reaction" Verified chr5:172633-173337 172633-173337 98.9% 291.14 381.50 328.43 268.20 361.42 216.57 336.32 298.31 288.99 1.24 1.21 1.20 -0.05 -0.25 Matched[1605]
YER011W TIR1 Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expression is downregulated at acidic pH and induced by cold shock and anaerobiosis; abundance is increased in cells cultured without shaking Verified chr5:175247-176011 175247-176011 73.5% 158.39 2142.67 149.49 113.90 121.01 90.76 1150.53 131.69 105.89 4.25 0.53 0.44 -0.31 -0.02 Frag>80[1607,1608]
YER012W PRE1 20S proteasome beta-type subunit; localizes to the nucleus throughout the cell cycle Verified chr5:177834-178430 177834-178430 98.7% 806.00 644.80 782.24 646.49 1269.23 761.88 725.40 714.37 1015.55 2.68 2.90 4.21 0.51 0.36 Matched[1610]
YER013W PRP22 "DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase, associates with lariat intermediates before the second catalytic step of splicing; mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes" Verified chr5:178840-182277 178840-182277 98.6% 53.67 66.35 47.18 54.55 53.67 58.98 60.01 50.87 56.32 0.22 0.21 0.23 0.15 0.62 Matched[1611]
YER014W HEM14 "Protoporphyrinogen oxidase, a mitochondrial enzyme that catalyzes the seventh step in the heme biosynthetic pathway, converting protoporphyrinogen IX to protoporphyrin IX" Verified chr5:182599-184218 182599-184218 98.6% 115.16 212.79 102.64 123.92 227.18 258.48 163.97 113.28 242.83 0.61 0.46 1.01 1.10 1.47 Matched[1612]
YER015W FAA2 "Long chain fatty acyl-CoA synthetase; accepts a wider range of acyl chain lengths than Faa1p, preferring C9:0-C13:0; involved in the activation of endogenous pools of fatty acids" Verified chr5:184540-186774 184540-186774 98.9% 37.99 29.40 45.68 47.49 42.06 28.04 33.70 46.59 35.05 0.12 0.19 0.15 -0.41 -0.06 Covered[1613]
YER014C-A BUD25 Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern Verified chr5:183730-184699 183730-184168,184677-184699 98.6% 160.32 311.86 138.36 147.14 331.63 314.06 236.09 142.75 322.84 0.87 0.58 1.34 1.18 -0.08
YER016W BIM1 Microtubule-binding protein that together with Kar9p makes up the cortical microtubule capture site and delays the exit from mitosis when the spindle is oriented abnormally Verified chr5:188276-189310 188276-189310 98.3% 306.76 316.59 276.28 248.75 239.90 138.63 311.68 262.52 189.27 1.15 1.07 0.78 -0.47 1.83 Covered/w/another[1614]
YER017C AFG3 "Component, with Yta12p, of the mitochondrial inner membrane m-AAA protease that mediates degradation of misfolded or unassembled proteins and is also required for correct assembly of mitochondrial enzyme complexes" Verified chr5:189502-191787 189502-191787 98.9% 215.92 219.90 228.31 201.76 244.24 219.90 217.91 215.04 232.07 0.80 0.87 0.96 0.11 0.50 Covered/w/another[1614]
YER018C SPC25 "Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering" Verified chr5:191958-192623 191958-192623 98.4% 129.76 174.03 157.24 106.86 135.87 88.54 151.90 132.05 112.21 0.56 0.54 0.46 -0.23 -0.28 Covered/w/another[1614]
YER019W ISC1 "Mitochondrial membrane localized inositol phosphosphingolipid phospholipase C, hydrolyzes complex sphingolipids to produce ceramide; activated by phosphatidylserine, cardiolipin, and phosphatidylglycerol; mediates Na+ and Li+ halotolerance" Verified chr5:192796-194229 192796-194229 98.5% 170.64 219.49 174.18 140.90 193.30 115.41 195.07 157.54 154.35 0.72 0.64 0.64 -0.03 -0.10 Covered/w/another[1614]
YER019C-A SBH2 "Ssh1p-Sss1p-Sbh2p complex component, involved in protein translocation into the endoplasmic reticulum; homologous to Sbh1p" Verified chr5:194272-194538 194272-194538 98.7% 1783.68 1415.56 1760.91 1540.80 1499.05 1001.90 1599.62 1650.85 1250.47 5.90 6.70 5.18 -0.40 -0.73 Matched[1615]
YER020W GPA2 "Nucleotide binding alpha subunit of the heterotrimeric G protein that interacts with the receptor Gpr1p, has signaling role in response to nutrients; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery" Verified chr5:195167-196516 195167-196516 98.3% 221.64 341.51 277.43 247.28 434.99 405.59 281.58 262.35 420.29 1.04 1.06 1.74 0.68 1.05 Matched[1617]
YER021W RPN3 "Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to the p58 subunit of the human 26S proteasome; temperature-sensitive alleles cause metaphase arrest, suggesting a role for the proteasome in cell cycle control" Verified chr5:196947-198518 196947-198518 98.8% 607.55 520.66 592.10 611.41 1005.28 780.03 564.10 601.75 892.66 2.08 2.44 3.70 0.57 0.65 Matched[1618]
YER022W SRB4 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation Verified chr5:198811-200874 198811-200874 98.8% 133.33 146.56 120.58 115.68 151.95 91.17 139.94 118.13 121.56 0.52 0.48 0.50 0.04 0.02 Matched[1619]
YER023W PRO3 "Delta 1-pyrroline-5-carboxylate reductase, catalyzes the last step in proline biosynthesis" Verified chr5:201075-201935 201075-201935 98.3% 1173.96 1211.75 1165.69 1105.46 999.16 875.15 1192.85 1135.57 937.16 4.40 4.61 3.88 -0.28 -0.11 Frag>80[1620,1621]
YER023C-A "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps verified gene PRO3; identified by gene-trapping, microarray expression analysis, and genome-wide homology searching" Dubious chr5:201521-201733 201521-201733 98.0% 1379.37 1479.94 1403.31 1254.84 1163.84 1039.31 1429.65 1329.08 1101.58 5.28 5.39 4.56 -0.27 NaN Matched[1621]
YER024W YAT2 "Carnitine acetyltransferase; has similarity to Yat1p, which is a carnitine acetyltransferase associated with the mitochondrial outer membrane" Verified chr5:202191-204962 202191-204962 98.8% 33.94 37.23 31.39 24.09 39.05 29.93 35.59 27.74 34.49 0.13 0.11 0.14 0.31 0.29 Frag>80[1621,1622,1623]
YER025W GCD11 "Gamma subunit of the translation initiation factor eIF2, involved in the identification of the start codon; binds GTP when forming the ternary complex with GTP and tRNAi-Met" Verified chr5:205250-206833 205250-206833 98.8% 954.73 684.42 826.93 743.85 157.21 147.62 819.58 785.39 152.41 3.03 3.19 0.63 -2.37 -1.87 Matched[1624]
YER026C CHO1 "Phosphatidylserine synthase, functions in phospholipid biosynthesis; catalyzes the reaction CDP-diaclyglycerol + L-serine = CMP + L-1-phosphatidylserine, transcriptionally repressed by myo-inositol and choline" Verified chr5:207643-208473 207643-208473 98.9% 851.37 632.44 1016.77 1103.13 1423.00 785.69 741.90 1059.95 1104.34 2.74 4.30 4.58 0.06 -0.20 Frag>80[1625,1626,1627]
YER027C GAL83 "One of three possible beta-subunits of the Snf1 kinase complex, allows nuclear localization of the Snf1 kinase complex in the presence of a nonfermentable carbon source; contains glycogen-binding domain" Verified chr5:208978-210231 208978-210231 99.0% 265.94 243.38 274.81 277.22 367.48 251.44 254.66 276.01 309.46 0.94 1.12 1.28 0.17 0.46 Matched[1628]
YER028C MIG3 "Probable transcriptional repressor involved in response to toxic agents such as hydroxyurea that inhibit ribonucleotide reductase; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, allowing induction of damage response genes" Verified chr5:210691-211875 210691-211875 98.6% 34.24 17.98 11.98 7.70 47.08 17.12 26.11 9.84 32.10 0.10 0.04 0.13 1.71 -0.81 Matched[1629]
YER029C SMB1 "Core Sm protein Sm B; part of heteroheptameric complex (with Smd1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm B and Sm B'" Verified chr5:212586-213176 212586-213176 99.4% 277.56 240.10 234.99 236.70 202.64 131.12 258.83 235.85 166.88 0.96 0.96 0.69 -0.50 -0.38 Matched[1630]
YER030W CHZ1 Histone chaperone for Htz1p/H2A-H2B dimer; required for the stabilization of the Chz1p-Htz1-H2B complex; has overlapping function with Nap1p; null mutant displays weak sensitivity to MMS and benomyl; contains a highly conserved CHZ motif Verified chr5:213436-213897 213436-213897 97.9% 725.33 539.57 714.27 601.49 1410.85 816.00 632.45 657.88 1113.42 2.33 2.67 4.61 0.76 -0.15 Matched[1631]
YER031C YPT31 "GTPase of the Ypt/Rab family, very similar to Ypt32p; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi" Verified chr5:214075-214746 214075-214746 99.2% 855.11 790.60 877.61 871.61 711.09 651.08 822.85 874.61 681.09 3.04 3.55 2.82 -0.36 -0.19 Matched[1632]
YER032W FIR1 "Protein involved in 3' mRNA processing, interacts with Ref2p; potential Cdc28p substrate" Verified chr5:215062-217692 215062-217692 99.0% 126.73 122.50 94.09 98.31 58.37 80.26 124.62 96.20 69.32 0.46 0.39 0.29 -0.47 -0.02 Covered/w/another[1633]
YER033C ZRG8 "Protein of unknown function; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; GFP-fusion protein is localized to the cytoplasm; transcription induced under conditions of zinc deficiency" Verified chr5:218056-221286 218056-221286 98.5% 51.21 75.09 44.93 53.41 84.21 145.47 63.15 49.17 114.84 0.23 0.20 0.48 1.22 1.66 Covered/w/another[1633]
YER034W Putative protein of unknown function; non-essential gene; expression induced upon calcium shortage Uncharacterized chr5:221845-222402 221845-222402 98.1% 120.53 87.66 74.87 60.26 157.05 115.05 104.09 67.57 136.05 0.38 0.27 0.56 1.01 0.91 Covered/w/another[1633]
YER035W EDC2 "RNA-binding protein, activates mRNA decapping directly by binding to the mRNA substrate and enhancing the activity of the decapping proteins Dcp1p and Dcp2p" Verified chr5:222638-223075 222638-223075 98.3% 160.20 318.08 215.92 222.89 1495.21 1019.25 239.14 219.41 1257.23 0.88 0.89 5.21 2.52 2.16 Matched[1634]
YER036C ARB1 "ATPase of the ATP-binding cassette (ABC) family involved in 40S and 60S ribosome biogenesis, has similarity to Gcn20p; shuttles from nucleus to cytoplasm, physically interacts with Tif6p, Lsg1p" Verified chr5:223366-225198 223366-225198 98.9% 932.07 542.15 785.37 659.07 329.81 306.09 737.11 722.22 317.95 2.72 2.93 1.32 -1.18 -0.45 Matched[1635]
YER037W PHM8 "Protein of unknown function, expression is induced by low phosphate levels and by inactivation of Pho85p" Verified chr5:225888-226853 225888-226853 98.9% 154.95 235.56 141.34 96.32 1001.92 598.85 195.25 118.83 800.38 0.72 0.48 3.32 2.75 2.87 Matched[1636]
YER038C KRE29 Essential subunit of the Mms21-Smc5-Smc6 complex; protein of unknown function; required for growth and DNA repair; heterozygous mutant shows haploinsufficiency in K1 killer toxin resistance Verified chr5:226857-228251 226857-228251 99.3% 51.97 63.51 39.70 41.14 203.54 99.60 57.74 40.42 151.57 0.21 0.16 0.63 1.91 0.28 Frag>80[1637]
YER038W-A "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 99% of ORF overlaps the verified gene HVG1; protein product detected in mitochondria" Dubious chr5:228450-228830 228450-228830 98.5% 53.32 77.31 63.98 58.65 77.31 77.31 65.31 61.31 77.31 0.24 0.25 0.32 0.33 NaN Matched[1638]
YER039C HVG1 "Protein of unknown function, has homology to Vrg4p" Verified chr5:228455-229204 228455-229204 98.4% 62.30 67.72 56.88 63.66 85.33 58.24 65.01 60.27 71.78 0.24 0.24 0.30 0.25 0.78 Matched[1638]
YER039C-A Putative protein of unknown function; YER039C-A is not an essential gene Uncharacterized chr5:229262-229480 229262-229480 99.0% 46.11 41.50 50.72 32.28 50.72 27.67 43.80 41.50 39.19 0.16 0.17 0.16 -0.08 0.83 Covered/w/another[1638]
YER040W GLN3 "Transcriptional activator of genes regulated by nitrogen catabolite repression (NCR), localization and activity regulated by quality of nitrogen source" Verified chr5:229794-231986 229794-231986 99.0% 81.54 101.35 63.58 61.73 52.52 52.98 91.45 62.65 52.75 0.34 0.25 0.22 -0.25 0.20 Covered/w/another[1639]
YER041W YEN1 "Protein of unknown function, has similarity to endonuclease Rth1p; potentially phosphorylated by Cdc28p" Verified chr5:232460-234739 232460-234739 98.8% 51.94 78.13 47.06 51.94 84.35 70.14 65.04 49.50 77.24 0.24 0.20 0.32 0.64 0.85 Covered/w/another[1639]
YER042W MXR1 "Peptide methionine sulfoxide reductase, reverses the oxidation of methionine residues; involved in oxidative damage repair, providing resistance to oxidative stress and regulation of lifespan" Verified chr5:234936-235490 234936-235490 98.8% 125.78 144.01 118.49 83.85 224.21 118.49 134.89 101.17 171.35 0.50 0.41 0.71 0.76 0.26 Covered/w/another[1639]
YER043C SAH1 "S-adenosyl-L-homocysteine hydrolase, catabolizes S-adenosyl-L-homocysteine which is formed after donation of the activated methyl group of S-adenosyl-L-methionine (AdoMet) to an acceptor" Verified chr5:235769-237118 235769-237118 98.8% 2148.08 1523.52 1995.88 1929.15 575.82 490.35 1835.80 1962.51 533.08 6.78 7.97 2.21 -1.88 -1.19 Matched[1640]
YER044C ERG28 "Endoplasmic reticulum membrane protein, may facilitate protein-protein interactions between the Erg26p dehydrogenase and the Erg27p 3-ketoreductase and/or tether these enzymes to the ER, also interacts with Erg6p" Verified chr5:237569-238015 237569-238015 98.8% 489.01 1109.33 504.86 577.30 697.29 504.86 799.17 541.08 601.08 2.95 2.20 2.49 0.15 -0.19 Frag>80[1641,1642]
YER044C-A MEI4 Meiosis-specific protein involved in recombination; required for chromosome synapsis; required for production of viable spores Verified chr5:238459-239773 238459-239622,239711-239773 99.3% 8.21 5.75 4.93 4.93 4.10 5.75 6.98 4.93 4.93 0.03 0.02 0.02 0.00 0.63
YER045C ACA1 "Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, may regulate transcription of genes involved in utilization of non-optimal carbon sources" Verified chr5:240031-241500 240031-241500 98.7% 103.34 143.29 92.31 68.20 54.42 48.22 123.31 80.26 51.32 0.46 0.33 0.21 -0.65 0.11 Covered/w/another[1643]
YER046W SPO73 "Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensible for both nuclear divisions during meiosis" Verified chr5:243179-243610 243179-243610 98.7% 82.09 133.69 98.50 86.78 159.48 91.47 107.89 92.64 125.48 0.40 0.38 0.52 0.44 -0.18 Covered/w/another[1643]
YER046W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr5:243699-244028 243699-244028 99.1% 70.36 85.66 64.24 116.25 183.56 79.54 78.01 90.25 131.55 0.29 0.37 0.55 0.54 NaN Covered/w/another[1643]
YER047C SAP1 "Putative ATPase of the AAA family, interacts with the Sin1p transcriptional repressor in the two-hybrid system" Verified chr5:243809-246502 243809-246502 99.0% 84.34 82.84 76.09 83.21 86.96 91.46 83.59 79.65 89.21 0.31 0.32 0.37 0.16 0.63 Covered/w/another[1643]
YER048C CAJ1 "Nuclear type II J heat shock protein of the E. coli dnaJ family, contains a leucine zipper-like motif, binds to non-native substrates for presentation to Ssa3p, may function during protein translocation, assembly and disassembly" Verified chr5:246981-248156 246981-248156 99.5% 595.94 507.87 527.54 508.73 878.09 655.79 551.91 518.13 766.94 2.04 2.10 3.18 0.57 0.78 Frag>80[1644,1645,1646]
YER048W-A ISD11 Protein required for mitochondrial iron-sulfur cluster biosynthesis Verified chr5:250717-251001 250717-251001 98.7% 547.23 586.32 511.70 476.16 906.13 557.89 566.78 493.93 732.01 2.09 2.00 3.03 0.57 0.14 Matched[1648]
YER049W TPA1 "Protein of unknown function; interacts with Sup45p (eRF1), Sup35p (eRF3) and Pab1p; has a role in translation termination efficiency, mRNA poly(A) tail length and mRNA stability" Verified chr5:251727-253661 251727-253661 98.7% 321.95 185.32 227.20 179.56 43.97 27.75 253.64 203.38 35.86 0.94 0.83 0.15 -2.50 -2.09 Matched[1650]
YER050C RSM18 "Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S18 ribosomal protein" Verified chr5:253970-254386 253970-254386 99.2% 449.46 563.03 488.12 529.20 853.00 543.70 506.24 508.66 698.35 1.87 2.06 2.89 0.46 0.19 Matched[1651]
YER051W JHD1 "JmjC domain family histone demethylase specific for H3-K36, similar to proteins found in human, mouse, drosophila, X. laevis, C. elegans, and S. pombe" Verified chr5:254655-256133 254655-256133 98.8% 99.24 91.72 74.60 50.65 93.77 47.91 95.48 62.63 70.84 0.35 0.25 0.29 0.18 0.44 Matched[1652]
YER052C HOM3 Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis Verified chr5:256374-257957 256374-257957 98.9% 387.58 630.22 337.14 284.78 114.29 124.51 508.90 310.96 119.40 1.88 1.26 0.49 -1.38 -0.65 Matched[1653]
YER053C PIC2 "Mitochondrial phosphate carrier, imports inorganic phosphate into mitochondria; functionally redundant with Mir1p but less abundant than Mir1p under normal conditions; expression is induced at high temperature" Verified chr5:258736-259638 258736-259638 99.1% 363.15 1097.26 519.58 583.27 1392.24 686.07 730.20 551.42 1039.15 2.70 2.24 4.31 0.91 0.50 Frag>80[1654,1655,1656]
YER053C-A Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum Uncharacterized chr5:260932-261045 260932-261045 98.8% 44.38 26.63 44.38 44.38 4500.00 3159.76 35.50 44.38 3829.88 0.13 0.18 15.87 6.43 4.56 Matched[1658]|Matched[1659]
YER054C GIP2 "Putative regulatory subunit of the protein phosphatase Glc7p, involved in glycogen metabolism; contains a conserved motif (GVNK motif) that is also found in Gac1p, Pig1p, and Pig2p" Verified chr5:262051-263697 262051-263697 99.3% 36.09 104.60 113.77 142.52 910.18 663.68 70.34 128.15 786.93 0.26 0.52 3.26 2.62 2.83 Frag>80[1660,1661]
YER055C HIS1 "ATP phosphoribosyltransferase, a hexameric enzyme, catalyzes the first step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control" Verified chr5:264891-265784 264891-265784 99.1% 1639.34 1779.24 1623.54 1413.69 596.84 326.06 1709.29 1518.62 461.45 6.31 6.16 1.91 -1.72 -2.60 Matched[1663]
YER056C FCY2 "Purine-cytosine permease, mediates purine (adenine, guanine, and hypoxanthine) and cytosine accumulation" Verified chr5:266511-268112 266511-268112 81.5% 788.44 1037.22 676.68 528.18 65.07 28.32 912.83 602.43 46.69 3.37 2.45 0.19 -3.69 -3.16 Matched[1665]
YER056C-A RPL34A "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl34Bp and has similarity to rat L34 ribosomal protein" Verified chr5:269421-270183 269421-269749,270147-270183 75.7% 4772.56 4061.37 3891.70 3191.34 1259.93 833.94 4416.97 3541.52 1046.93 16.31 14.38 4.34 -1.76 -2.83 Frag>80[1667,1668,1669]
YER057C HMF1 "Member of the p14.5 protein family with similarity to Mmf1p, functionally complements Mmf1p function when targeted to mitochondria; heat shock inducible; high-dosage growth inhibitor; forms a homotrimer in vitro" Verified chr5:270735-271124 270735-271124 98.6% 1408.86 1772.77 1289.29 1229.50 1109.93 1034.55 1590.82 1259.40 1072.24 5.87 5.11 4.44 -0.23 -0.04 Matched[1670]
YER058W PET117 Protein required for assembly of cytochrome c oxidase Verified chr5:271766-272089 271766-272089 97.8% 151.42 173.50 198.74 205.05 542.59 365.93 162.46 201.89 454.26 0.60 0.82 1.88 1.17 0.83 Matched[1672]
YER059W PCL6 Pho85p cyclin of the Pho80p subfamily; forms the major Glc8p kinase together with Pcl7p and Pho85p; involved in the control of glycogen storage by Pho85p; stabilized by Elongin C binding Verified chr5:272622-273884 272622-273884 98.7% 145.96 138.75 157.19 125.91 208.52 125.11 142.36 141.55 166.82 0.53 0.57 0.69 0.24 0.68 Matched[1673]
YER060W FCY21 "Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function" Verified chr5:274565-276151 274565-276151 92.3% 155.02 167.99 116.09 96.97 47.12 28.68 161.51 106.53 37.90 0.60 0.43 0.16 -1.49 -0.91 Covered[1674]
YER060W-A FCY22 "Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function" Verified chr5:276570-278162 276570-278162 75.1% 108.66 137.08 84.42 45.97 19.22 30.09 122.87 65.19 24.66 0.45 0.26 0.10 -1.40 -2.78 Frag<80[1675]
YER061C CEM1 Mitochondrial beta-keto-acyl synthase with possible role in fatty acid synthesis; required for mitochondrial respiration Verified chr5:278296-279624 278296-279624 99.0% 162.69 193.10 155.09 175.62 103.39 101.87 177.90 165.35 102.63 0.66 0.67 0.43 -0.69 -0.36 Matched[1676]
YER062C HOR2 "One of two redundant DL-glycerol-3-phosphatases (RHR2/GPP1 encodes the other) involved in glycerol biosynthesis; induced in response to hyperosmotic stress and oxidative stress, and during the diauxic transition" Verified chr5:279928-280680 279928-280680 97.6% 657.40 1248.11 778.54 684.63 1388.31 1094.31 952.76 731.58 1241.31 3.52 2.97 5.14 0.76 0.99 Matched[1677]
YER063W THO1 "Conserved nuclear RNA-binding protein; specifically binds to transcribed chromatin in a THO- and RNA-dependent manner, genetically interacts with shuttling hnRNP NAB2; overproduction suppresses transcriptional defect caused by hpr1 mutation" Verified chr5:281708-282364 281708-282364 98.3% 748.02 693.81 689.17 613.28 630.32 371.68 720.91 651.22 501.00 2.66 2.64 2.08 -0.38 -0.27 Frag>80[1678,1679]
YER064C Non-essential nuclear protein; null mutation has global effects on transcription Uncharacterized chr5:282703-284220 282703-284220 98.9% 428.29 664.08 278.42 227.13 148.53 138.54 546.18 252.78 143.54 2.02 1.03 0.59 -0.82 -0.24 Matched[1680]
YER065C ICL1 "Isocitrate lyase, catalyzes the formation of succinate and glyoxylate from isocitrate, a key reaction of the glyoxylate cycle; expression of ICL1 is induced by growth on ethanol and repressed by growth on glucose" Verified chr5:285239-286912 285239-286912 99.0% 83.31 80.29 73.04 59.76 95.98 53.73 81.80 66.40 74.85 0.30 0.27 0.31 0.17 0.16 Matched[1681]
YER066W Putative protein of unknown function; YER066W is not an essential gene Uncharacterized chr5:290240-290797 290240-290797 70.6% 91.40 152.33 60.93 71.09 109.17 71.09 121.87 66.01 90.13 0.45 0.27 0.37 0.45 0.46 Frag<80[1682,1683,1684]
YER067W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YER067W is not an essential gene Uncharacterized chr5:292064-292549 292064-292549 98.8% 539.49 874.85 1206.04 1233.12 13210.21 7134.18 707.17 1219.58 10172.19 2.61 4.95 42.15 3.06 1.98 Matched[1686]
YER066C-A "Dubious open reading frame unlikely to encode a protein, partially overlaps uncharacterized ORF YER067W" Dubious chr5:291701-292201 291701-292201 98.9% 211.98 393.67 474.43 547.11 4609.02 2545.76 302.83 510.77 3577.39 1.12 2.07 14.82 2.81 0.27 Frag>80[1685,1686]
YER067C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YER067W" Dubious chr5:292238-292561 292238-292561 98.9% 549.21 823.82 1226.37 1195.16 13917.57 7479.91 686.52 1210.77 10698.74 2.53 4.91 44.33 3.14 NaN Matched[1686]
YER068W MOT2 "Component of the CCR4-NOT complex, which has multiple roles in transcription regulation, mRNA degradation, and post-transcriptional modifications; with Ubc4p, ubiquitylates subunits of the nascent polypeptide-associated complex (NAC)" Verified chr5:293048-294811 293048-294811 98.9% 220.11 168.52 202.34 192.02 128.40 124.39 194.32 197.18 126.39 0.72 0.80 0.52 -0.64 0.05 Matched[1687]
YER069W "ARG5,6" "Protein that is processed in the mitochondrion to yield acetylglutamate kinase and N-acetyl-gamma-glutamyl-phosphate reductase, which catalyze the 2nd and 3rd steps in arginine biosynthesis; enzymes form a complex with Arg2p" Verified chr5:295408-297999 295408-297999 98.9% 55.01 147.09 47.60 36.67 61.64 58.13 101.05 42.14 59.89 0.37 0.17 0.25 0.51 0.70 Matched[1688]
YER068C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr5:295299-295730 295299-295730 99.0% 18.71 58.47 23.39 23.39 39.76 42.10 38.59 23.39 40.93 0.14 0.09 0.17 0.81 NaN Covered/w/another[1688]
YER070W RNR1 "Ribonucleotide-diphosphate reductase (RNR), large subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits" Verified chr5:298948-301614 298948-301614 97.1% 811.48 747.01 629.26 464.42 50.57 20.85 779.24 546.84 35.71 2.88 2.22 0.15 -3.94 -2.86 Matched[1689]
YER071C Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern Uncharacterized chr5:301945-302325 301945-302325 99.3% 145.33 145.33 171.75 147.97 288.01 200.81 145.33 159.86 244.41 0.54 0.65 1.01 0.61 -0.08 Matched[1690]
YER072W VTC1 "Vacuolar transporter chaperon (VTC) involved in distributing V-ATPase and other membrane proteins; together with other VTC proteins, forms a heterotetrameric complex that associates with the SNARE Nyv1p and the V0 sector of the V-ATPase" Verified chr5:302804-303193 302804-303193 98.7% 3504.65 3281.23 3686.51 3024.03 1987.44 1234.03 3392.94 3355.27 1610.74 12.52 13.62 6.67 -1.06 -1.55 Matched[1691]
YER073W ALD5 "Mitochondrial aldehyde dehydrogenase, involved in regulation or biosynthesis of electron transport chain components and acetate formation; activated by K+; utilizes NADP+ as the preferred coenzyme; constitutively expressed" Verified chr5:304027-305589 304027-305589 98.6% 439.38 737.28 360.85 309.58 84.37 44.78 588.33 335.22 64.58 2.17 1.36 0.27 -2.38 -2.04 Frag>80[1692,1693,1694]
YER074W RPS24A Protein component of the small (40S) ribosomal subunit; identical to Rps24Bp and has similarity to rat S24 ribosomal protein Verified chr5:306319-307192 306319-306321,306788-307192 32.6% 8792.23 7084.93 7716.70 5625.82 2286.43 1850.20 7938.58 6671.26 2068.32 29.30 27.08 8.57 -1.69 -2.41 Frag>80[1695,1696]
YER074W-A YOS1 "Integral membrane protein required for ER to Golgi transport; localized to the Golgi, the ER, and COPII vesicles; interacts with Yip1p and Yif1p" Verified chr5:307649-308119 307649-307742,307845-307952,308064-308119 98.5% 472.21 460.40 397.44 401.38 645.35 381.70 466.31 399.41 513.53 1.72 1.62 2.13 0.36 -0.20 Matched[1697]
YER075C PTP3 Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the cytoplasm Verified chr5:308409-311195 308409-311195 98.5% 57.93 67.04 47.00 34.25 18.95 14.94 62.48 40.62 16.94 0.23 0.16 0.07 -1.26 -0.20 Matched[1698]
YER076W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YER076C" Dubious chr5:313386-313733 313386-313733 98.9% 29.04 81.32 69.70 37.75 55.18 55.18 55.18 53.73 55.18 0.20 0.22 0.23 0.04 NaN Covered/w/another[1699]
YER076C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; analysis of HA-tagged protein suggests a membrane localization" Uncharacterized chr5:312586-313494 312586-313494 98.9% 83.39 92.28 81.16 80.05 107.85 55.59 87.83 80.61 81.72 0.32 0.33 0.34 0.02 0.47 Matched[1699]
YER077C Hypothetical protein Uncharacterized chr5:314530-316596 314530-316596 99.4% 67.68 67.19 61.35 48.69 61.83 51.12 67.43 55.02 56.48 0.25 0.22 0.23 0.04 0.51 Frag>80[1700,1701]
YER078C "Metallopeptidase, localized to the mitochondrial matrix" Uncharacterized chr5:316803-318338 316803-318338 99.1% 141.83 184.51 145.12 120.82 154.31 122.79 163.17 132.97 138.55 0.60 0.54 0.57 0.06 0.21 Matched[1702]
YER078W-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr5:318642-318806 318642-318806 99.8% 0.00 6.07 0.00 12.15 30.37 18.22 3.04 6.07 24.30 0.01 0.02 0.10 2.00 NaN Covered/w/another[1702]
YER079W Putative protein of unknown function Uncharacterized chr5:318916-319548 318916-319548 98.9% 217.19 392.87 321.00 298.64 1226.51 1063.61 305.03 309.82 1145.06 1.13 1.26 4.74 1.89 1.92 Matched[1703]
YER080W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr5:319959-321842 319959-321842 98.8% 318.02 374.97 355.63 364.76 526.46 414.72 346.49 360.19 470.59 1.28 1.46 1.95 0.39 0.64 Matched[1704]
YER079C-A "Dubious open reading frame unlikely to encode a protein, partially overlaps uncharacterized ORF YER080W" Dubious chr5:319898-320236 319898-320236 98.6% 197.48 218.43 164.57 272.29 215.43 302.21 207.95 218.43 258.82 0.77 0.89 1.07 0.24 NaN Covered/w/another[1704]
YER081W SER3 "3-phosphoglycerate dehydrogenase, catalyzes the first step in serine and glycine biosynthesis; isozyme of Ser33p" Verified chr5:322682-324091 322682-324091 85.3% 781.14 932.55 678.82 554.87 430.09 275.36 856.85 616.85 352.72 3.16 2.50 1.46 -0.81 -0.21 Matched[1706]
YER082C UTP7 "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" Verified chr5:324268-325932 324268-325932 99.1% 273.81 158.11 161.14 137.51 27.87 12.12 215.96 149.33 19.99 0.80 0.61 0.08 -2.90 -2.05 Matched[1707]
YER083C GET2 Subunit of the GET complex; required for meiotic nuclear division and for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion; may be involved in cell wall function Verified chr5:326170-327027 326170-327027 98.5% 337.18 336.00 354.92 328.90 375.04 356.11 336.59 341.91 365.57 1.24 1.39 1.51 0.10 0.18 Matched[1708]
YER084W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr5:327061-327447 327061-327447 99.1% 10.42 15.64 36.49 20.85 86.00 70.37 13.03 28.67 78.18 0.05 0.12 0.32 1.45 -0.30 Matched[1709]
YER084W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr5:327594-328106 327594-328106 99.5% 5.88 5.88 1.96 11.76 13.72 7.84 5.88 6.86 10.78 0.02 0.03 0.04 0.65 NaN Frag<80[1709,1710]
YER085C Putative protein of unknown function Uncharacterized chr5:327615-328136 327615-328136 99.5% 5.78 3.85 1.93 5.78 7.70 5.78 4.81 3.85 6.74 0.02 0.02 0.03 0.81 -0.52 Frag<80[1709,1710]
YER086W ILV1 "Threonine deaminase, catalyzes the first step in isoleucine biosynthesis; expression is under general amino acid control; ILV1 locus exhibits highly positioned nucleosomes whose organization is independent of known ILV1 regulation" Verified chr5:328473-330203 328473-330203 99.0% 702.19 794.42 693.44 698.11 137.75 121.41 748.30 695.77 129.58 2.76 2.82 0.54 -2.42 -1.66 Matched[1711]
YER087W "Protein with similarity to tRNA synthetases; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr5:330572-332302 330572-332302 98.7% 96.61 98.95 118.27 97.78 172.73 121.79 97.78 108.03 147.26 0.36 0.44 0.61 0.45 0.58 Matched[1712]
YER087C-A "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; overlaps the uncharacterized gene YER087W, a putative tRNA synthetase" Dubious chr5:331813-332364 331813-332364 98.7% 143.18 159.71 150.53 130.34 264.34 152.36 151.45 140.43 208.35 0.56 0.57 0.86 0.57 NaN Covered/w/another[1712]
YER087C-B SBH1 Beta subunit of the Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p); involved in protein translocation into the endoplasmic reticulum; interacts with the exocyst complex and also with Rtn1p; homologous to Sbh2p Verified chr5:332578-332826 332578-332826 98.6% 1095.72 1018.33 1103.87 920.57 851.32 553.97 1057.03 1012.22 702.65 3.90 4.11 2.91 -0.53 -0.46 Matched[1713]
YER088C DOT6 "Protein of unknown function, involved in telomeric gene silencing and filamentation" Verified chr5:333172-335184 333172-335184 98.2% 487.28 523.20 486.77 498.91 719.02 654.26 505.24 492.84 686.64 1.87 2.00 2.84 0.48 0.87 Covered/w/another[1714]
YER088W-B "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr5:335923-336069 335923-336069 97.6% 536.74 501.89 515.83 341.56 383.39 264.89 519.31 428.70 324.14 1.92 1.74 1.34 -0.40 NaN Covered/w/another[1714]
YER088C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr5:335692-336015 335692-336015 98.2% 377.01 289.04 279.62 185.36 223.07 113.10 333.03 232.49 168.08 1.23 0.94 0.70 -0.47 NaN Covered/w/another[1714]
YER089C PTC2 Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress induced kinase activity; dephosphorylates Ire1p to downregulate the unfolded protein response; dephosphorylates Cdc28p; role in DNA checkpoint inactivation Verified chr5:335942-337336 335942-337336 98.7% 429.97 476.46 403.83 323.93 301.42 203.37 453.21 363.88 252.39 1.67 1.48 1.05 -0.53 -0.20 Covered/w/another[1714]
YER090W TRP2 "Anthranilate synthase, catalyzes the initial step of tryptophan biosynthesis, forms multifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp3p" Verified chr5:337945-339468 337945-339468 98.9% 361.67 437.32 352.38 378.92 176.52 189.13 399.49 365.65 182.82 1.47 1.48 0.76 -1.00 -0.32 Frag>80[1715,1716]
YER090C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr5:338318-338407 338318-338407 99.2% 179.19 291.18 302.38 302.38 89.59 156.79 235.18 302.38 123.19 0.87 1.23 0.51 -1.30 NaN Covered/w/another[1715]
YER091C MET6 "Cobalamin-independent methionine synthase, involved in amino acid biosynthesis; requires a minimum of two glutamates on the methyltetrahydrofolate substrate, similar to bacterial metE homologs" Verified chr5:339860-342163 339860-342163 98.8% 297.48 604.19 528.61 322.09 80.85 60.64 450.83 425.35 70.74 1.66 1.73 0.29 -2.59 -1.87 Matched[1717]
YER091C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr5:342386-342607 342386-342607 98.7% 0.00 9.13 4.56 0.00 13.69 9.13 4.56 2.28 11.41 0.02 0.01 0.05 2.32 0.47 Overlap[1717]
YER092W IES5 Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions Verified chr5:342851-343228 342851-343228 98.5% 290.19 276.76 225.71 225.71 241.83 231.08 283.48 225.71 236.45 1.05 0.92 0.98 0.07 0.03 Matched[1718]
YER093C TSC11 "Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p), a membrane-associated complex that regulates actin cytoskeletal dynamics during polarized growth and cell wall integrity; involved in sphingolipid metabolism; contains a RasGEFN domain" Verified chr5:343316-347608 343316-347608 99.2% 61.98 62.69 50.48 43.20 40.85 45.78 62.33 46.84 43.32 0.23 0.19 0.18 -0.11 0.38 Matched[1719]
YER093C-A Putative protein of unknown function; YER093C-A contains an intron Uncharacterized chr5:347908-348396 347908-348197,348273-348396 98.8% 88.06 95.39 119.85 129.64 139.42 83.16 91.72 124.75 111.29 0.34 0.51 0.46 -0.16 0.04 Matched[1720]
YER094C PUP3 Beta subunit of the 20S proteasome involved in ubiquitin-dependent catabolism; human homolog is subunit C10 Verified chr5:348725-349342 348725-349342 98.8% 1034.65 828.38 936.43 767.80 1717.33 800.55 931.51 852.11 1258.94 3.44 3.46 5.22 0.56 0.37 Frag>80[1721,1722]
YER095W RAD51 "Strand exchange protein, forms a helical filament with DNA that searches for homology; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; homolog of Dmc1p and bacterial RecA protein" Verified chr5:349976-351178 349976-351178 98.2% 187.97 188.82 220.99 192.20 264.17 235.39 188.39 206.60 249.78 0.70 0.84 1.03 0.27 0.54 Frag>80[1723,1724]
YER096W SHC1 "Sporulation-specific activator of Chs3p (chitin synthase III), required for the synthesis of the chitosan layer of ascospores; has similarity to Skt5p, which activates Chs3p during vegetative growth; transcriptionally induced at alkaline pH" Verified chr5:351694-353232 351694-353232 98.7% 16.45 6.58 11.85 10.53 63.18 49.36 11.52 11.19 56.27 0.04 0.05 0.23 2.33 2.68 Matched[1725]
YER097W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr5:355136-355465 355136-355465 99.1% 3.06 15.29 6.12 6.12 30.58 24.46 9.17 6.12 27.52 0.03 0.02 0.11 2.17 1.55 Overlap[1726]
YER098W UBP9 "Ubiquitin carboxyl-terminal hydrolase, ubiquitin-specific protease that cleaves ubiquitin-protein fusions" Verified chr5:355462-357726 355462-357726 98.7% 77.38 89.91 68.88 75.15 162.37 167.74 83.64 72.01 165.05 0.31 0.29 0.68 1.20 1.03 Covered/w/another[1726]
YER099C PRS2 "5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes" Verified chr5:358101-359057 358101-359057 98.8% 191.42 227.37 188.24 151.23 191.42 141.71 209.39 169.74 166.56 0.77 0.69 0.69 -0.03 0.16 Covered/w/another[1726]
YER100W UBC6 Ubiquitin-conjugating enzyme involved in ER-associated protein degradation; located at the cytosolic side of the ER membrane; tail region contains a transmembrane segment at the C-terminus; substrate of the ubiquitin-proteasome pathway Verified chr5:359558-360310 359558-360310 98.5% 373.32 446.09 378.71 327.49 436.66 361.19 409.70 353.10 398.92 1.51 1.43 1.65 0.18 0.41 Covered/w/another[1726]
YER101C AST2 "Protein that may have a role in targeting of plasma membrane [H+]ATPase (Pma1p) to the plasma membrane, as suggested by analysis of genetic interactions" Verified chr5:360498-361790 360498-361790 99.2% 68.60 84.97 67.04 45.21 99.78 95.10 76.78 56.13 97.44 0.28 0.23 0.40 0.80 1.16 Covered/w/another[1726]
YER102W RPS8B Protein component of the small (40S) ribosomal subunit; identical to Rps8Ap and has similarity to rat S8 ribosomal protein Verified chr5:362728-363698 362728-362729,363089-363698 20.5% 6639.66 4694.79 5563.60 4495.52 1115.91 828.96 5667.22 5029.56 972.43 20.92 20.42 4.03 -2.37 -3.22 Frag<80[1727,1728]
YER103W SSA4 Heat shock protein that is highly induced upon stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the HSP70 family; cytoplasmic protein that concentrates in nuclei upon starvation Verified chr5:364585-366513 364585-366513 97.9% 155.21 274.93 191.23 155.21 36221.43 25410.67 215.07 173.22 30816.05 0.79 0.70 127.68 7.47 5.45 Matched[1730]
YER104W RTT105 Protein with a role in regulation of Ty1 transposition Verified chr5:366798-367424 366798-367424 98.5% 51.84 68.03 69.65 50.22 27.54 34.02 59.94 59.94 30.78 0.22 0.24 0.13 -0.96 0.07 Matched[1731]
YER105C NUP157 "Abundant subunit of the nuclear pore complex (NPC), present on both sides of the NPC, has similarity to Nup170p" Verified chr5:367834-372009 367834-372009 99.1% 159.95 131.68 128.79 116.46 86.50 119.85 145.82 122.62 103.17 0.54 0.50 0.43 -0.25 0.16 Matched[1732]
YER106W MAM1 "Monopolin, kinetochore associated protein involved in chromosome attachment to meiotic spindle" Verified chr5:372322-373230 372322-373230 98.7% 5.57 12.26 8.91 3.34 10.03 4.46 8.91 6.13 7.24 0.03 0.02 0.03 0.24 0.04 Frag<80[1733]
YER107W-A "Dubious open reading frame unlikely to encode a protein, partially overlaps verified ORF GLE2/YER107C" Dubious chr5:374390-374710 374390-374710 99.2% 191.52 178.96 163.27 150.71 103.61 109.89 185.24 156.99 106.75 0.68 0.64 0.44 -0.56 NaN Covered/w/another[1734]
YER107C GLE2 "Component of the nuclear pore complex required for polyadenylated RNA export but not for protein import, homologous to S. pombe Rae1p" Verified chr5:373444-374541 373444-374541 99.1% 225.21 191.20 238.08 178.33 165.46 99.28 208.20 208.20 132.37 0.77 0.85 0.55 -0.65 -0.49 Frag>80[1733,1734]
YER109C FLO8 "Transcription factor required for flocculation, diploid filamentous growth, and haploid invasive growth; genome reference strain S288C and most laboratory strains have a mutation in this gene" Verified chr5:375211-377610 375211-377610 98.5% 106.18 107.03 90.53 79.53 55.00 46.11 106.61 85.03 50.55 0.39 0.35 0.21 -0.75 -0.09 Matched[1735]
YER110C KAP123 "Karyopherin beta, mediates nuclear import of ribosomal proteins prior to assembly into ribosomes and import of histones H3 and H4; localizes to the nuclear pore, nucleus, and cytoplasm; exhibits genetic interactions with RAI1" Verified chr5:378758-382099 378758-382099 98.9% 422.57 197.52 292.50 257.11 34.79 30.55 310.05 274.81 32.67 1.14 1.12 0.14 -3.07 -1.88 Matched[1737]
YER111C SWI4 "DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activator that in concert with MBF (Mbp1-Swi6p) regulates late G1-specific transcription of targets including cyclins and genes required for DNA synthesis and repair" Verified chr5:382591-385872 382591-385872 99.2% 112.67 105.00 95.48 101.00 107.14 120.96 108.83 98.24 114.05 0.40 0.40 0.47 0.22 0.62 Matched[1738]
YER112W LSM4 "Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA" Verified chr5:387228-387791 387228-387791 98.8% 373.23 348.11 364.26 369.64 321.20 224.30 360.67 366.95 272.75 1.33 1.49 1.13 -0.43 -0.55 Covered/w/another[1739]
YER113C "Non-essential golgi localized protein of unknown function; contains niine potential transmembrane domains and has similarity to the endosomal protein, Emp70p" Uncharacterized chr5:387928-390048 387928-390048 99.2% 137.41 142.16 135.03 109.83 103.65 98.89 139.78 122.43 101.27 0.52 0.50 0.42 -0.27 -0.37 Covered/w/another[1739]
YER114C BOI2 "Protein implicated in polar growth, functionally redundant with Boi1p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain" Verified chr5:390586-393708 390586-393708 98.9% 134.01 116.53 98.08 90.96 65.06 70.57 125.27 94.52 67.82 0.46 0.38 0.28 -0.48 0.12 Covered/w/another[1739]
YER115C SPR6 "Protein of unknown function, expressed during sporulation; not required for sporulation, but gene exhibits genetic interactions with other genes required for sporulation" Verified chr5:394288-394863 394288-394863 98.8% 228.32 272.23 168.61 151.04 170.36 119.43 250.27 159.82 144.90 0.92 0.65 0.60 -0.14 0.13 Covered/w/another[1740]
YER116C SLX8 Subunit of the Slx5-Slx8 substrate-specific ubiquitin ligase complex; stimulated by prior attachment of SUMO to the substrate Verified chr5:395344-396168 395344-396168 99.1% 122.27 133.27 88.03 83.14 152.84 112.49 127.77 85.59 132.66 0.47 0.35 0.55 0.63 1.10 Covered/w/another[1740]
YER117W RPL23B "Protein component of the large (60S) ribosomal subunit, identical to Rpl23Ap and has similarity to E. coli L14 and rat L23 ribosomal proteins" Verified chr5:396765-397649 396765-396806,397278-397649 58.1% 8366.97 6057.12 7295.14 5616.76 2093.82 1512.20 7212.05 6455.95 1803.01 26.62 26.21 7.47 -1.84 -2.30 Matched[1741]
YER118C SHO1 "Transmembrane osmosensor, participates in activation of both the Cdc42p- and MAP kinase-dependent filamentous growth pathway and the high-osmolarity glycerol response pathway" Verified chr5:397948-399051 397948-399051 99.0% 295.62 217.82 264.50 203.18 98.84 56.74 256.72 233.84 77.79 0.95 0.95 0.32 -1.59 -1.48 Matched[1742]
YER119C AVT6 "Vacuolar amino acid transporter, exports aspartate and glutamate from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters" Verified chr5:399492-400838 399492-400838 98.5% 158.26 204.23 196.69 168.81 371.53 311.99 181.24 182.75 341.76 0.67 0.74 1.42 0.90 1.30 Matched[1743]
YER120W SCS2 "Integral ER membrane protein that regulates phospholipid metabolism via an interaction with the FFAT motif of Opi1p, also involved in telomeric silencing, disruption causes inositol auxotrophy above 34 degrees C, VAP homolog" Verified chr5:401131-401865 401131-401865 98.5% 1106.35 1167.13 1135.36 1048.34 888.12 776.24 1136.74 1091.85 832.18 4.20 4.43 3.45 -0.39 -0.32 Matched[1744]
YER119C-A "Dubious open reading frame, not conserved in closely related Saccharomyces species; deletion mutation blocks replication of Brome mosaic virus in S. cerevisiae, but this is likely due to effects on the overlapping gene SCS2" Dubious chr5:400863-401234 400863-401234 99.2% 276.49 257.51 346.96 230.40 233.11 216.85 267.00 288.68 224.98 0.99 1.17 0.93 -0.36 0.69 Frag<80[1744]
YER121W Putative protein of unknown function; may be involved in phosphatase regulation and/or generation of precursor metabolites and energy Uncharacterized chr5:402371-402715 402371-402715 98.6% 32.35 41.17 67.64 41.17 1388.07 814.61 36.76 54.41 1101.34 0.14 0.22 4.56 4.34 2.00 Matched[1746]
YER122C GLO3 "ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Gcs1p" Verified chr5:402867-404348 402867-404348 99.2% 777.71 672.92 645.71 647.07 531.40 529.36 725.31 646.39 530.38 2.68 2.62 2.20 -0.29 0.09 Matched[1747]
YER123W YCK3 "Palmitoylated, vacuolar membrane-localized casein kinase I isoform; negatively regulates vacuole fusion during hypertonic stress via phosphorylation of the HOPS complex subunit, Vps41p; shares overlapping essential functions with Hrr25p" Verified chr5:404809-406383 404809-406383 98.8% 172.23 180.59 145.88 176.73 110.54 104.11 176.41 161.31 107.32 0.65 0.65 0.44 -0.59 -0.10 Matched[1748]
YER124C DSE1 "Daughter cell-specific protein, may participate in pathways regulating cell wall metabolism; deletion affects cell separation after division and sensitivity to drugs targeted against the cell wall" Verified chr5:407338-409059 407338-409059 99.3% 494.88 529.39 407.14 323.49 372.04 190.70 512.14 365.31 281.37 1.89 1.48 1.17 -0.38 -0.38 Matched[1749]
YER125W RSP5 "Ubiquitin-protein ligase involved in ubiquitin-mediated protein degradation; functions in multivesicular body sorting, heat shock response and ubiquitylation of arrested RNAPII; contains a hect (homologous to E6-AP carboxyl terminus) domain" Verified chr5:410185-412614 410185-412614 98.7% 431.45 411.86 473.56 463.97 342.24 327.65 421.66 468.76 334.95 1.56 1.90 1.39 -0.48 -0.00 Matched[1750]
YER126C NSA2 "Protein constituent of 66S pre-ribosomal particles, contributes to processing of the 27S pre-rRNA" Verified chr5:413390-414175 413390-414175 99.3% 504.70 257.47 324.08 275.41 37.15 30.74 381.08 299.74 33.95 1.41 1.22 0.14 -3.14 -3.94 Matched[1752]
YER127W LCP5 Essential protein involved in maturation of 18S rRNA; depletion leads to inhibited pre-rRNA processing and reduced polysome levels; localizes primarily to the nucleolus Verified chr5:414477-415550 414477-415550 98.2% 161.24 139.42 105.28 110.02 21.81 12.33 150.33 107.65 17.07 0.55 0.44 0.07 -2.66 -3.17 Covered/w/another[1753]
YER128W Putative protein of unknown function Uncharacterized chr5:415855-416466 415855-416466 98.6% 66.29 107.72 69.60 64.63 69.60 48.06 87.00 67.12 58.83 0.32 0.27 0.24 -0.19 0.85 Covered/w/another[1753]
YER129W SAK1 "Upstream serine/threonine kinase for the SNF1 complex; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome" Verified chr5:417277-420705 417277-420705 98.7% 168.64 158.01 127.89 95.40 72.66 73.84 163.33 111.64 73.25 0.60 0.45 0.30 -0.61 0.28 Covered/w/another[1753]
YER130C Hypothetical protein Uncharacterized chr5:421111-422442 421111-422442 99.1% 138.62 112.86 90.90 71.20 109.08 71.20 125.74 81.05 90.14 0.46 0.33 0.37 0.15 0.32 Covered/w/another[1753]
YER131W RPS26B Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Ap and has similarity to rat S26 ribosomal protein Verified chr5:423586-424307 423586-423587,423948-424307 71.1% 8208.58 6241.94 6906.56 5779.43 742.35 202.11 7225.26 6343.00 472.23 26.67 25.75 1.96 -3.75 -5.03 Matched[1754]
YER132C PMD1 "Protein with an N-terminal kelch-like domain, putative negative regulator of early meiotic gene expression; required, with Mds3p, for growth under alkaline conditions" Verified chr5:425184-430445 425184-430445 98.9% 70.15 65.72 48.62 36.13 22.87 38.24 67.94 42.38 30.56 0.25 0.17 0.13 -0.47 -0.01 Frag<80[1755,1756]
YER133W GLC7 "Catalytic subunit of type 1 serine/threonine protein phosphatase, involved in many processes including glycogen metabolism, sporulation, and mitosis; interacts with multiple regulatory subunits; predominantly isolated with Sds22p" Verified chr5:432491-433954 432491-432667,433193-433954 98.8% 1564.87 1547.62 1479.73 1577.80 2774.08 1752.39 1556.24 1528.76 2263.24 5.74 6.21 9.38 0.57 -0.96 Frag>80[1758,1759,1760,1761]
YER133W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps uncharacterized gene YER134C." Dubious chr5:437187-437528 437187-437528 99.4% 303.05 305.99 261.86 332.48 714.97 423.69 304.52 297.17 569.33 1.12 1.21 2.36 0.94 NaN Matched[1764]
YER134C Putative protein of unknown function; non-essential gene Uncharacterized chr5:437263-437799 437263-437799 99.0% 240.68 304.61 242.56 297.09 565.97 398.62 272.64 269.82 482.29 1.01 1.10 2.00 0.84 0.98 Frag>80[1764,1765]
YER135C Dubious open reading frame unlikely to encode a protein; YER135C is not an essential gene Dubious chr5:437948-438340 437948-438340 99.2% 2.57 0.00 5.13 0.00 17.96 20.53 1.28 2.57 19.25 0.00 0.01 0.08 2.91 0.63 Frag<80[1765]
YER136W GDI1 "GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by regulating the dissociation of GDP from the Sec4/Ypt/rab family of GTP binding proteins" Verified chr5:439612-440967 439612-440967 98.9% 737.51 640.57 756.15 760.63 864.28 602.54 689.04 758.39 733.41 2.54 3.08 3.04 -0.05 0.28 Matched[1766]
YER137W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr5:441571-441876 441571-441876 99.6% 29.54 32.82 22.97 6.56 6.56 6.56 31.18 14.77 6.56 0.12 0.06 0.03 -1.17 NaN Matched[1767]
YER137C Putative protein of unknown function Uncharacterized chr5:441369-441815 441369-441815 99.5% 17.99 33.74 29.24 11.25 13.50 11.25 25.87 20.24 12.37 0.10 0.08 0.05 -0.71 -0.54 Matched[1767]
YER138W-A Putative protein of unknown function Uncharacterized chr5:449470-449574 449470-449574 5.9% 161.07 161.07 0.00 0.00 0.00 161.07 161.07 0.00 80.54 0.59 0.00 0.33 Inf -0.55 Matched[1770]
YER139C Putative protein of unknown function; YER139C has been shown to be required for growth at high temperatures; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr5:450558-451238 450558-451238 99.4% 82.74 78.31 79.78 81.26 125.58 97.51 80.52 80.52 111.55 0.30 0.33 0.46 0.47 0.70 Matched[1771]
YER140W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr5:451560-453230 451560-453230 98.8% 66.04 74.52 49.08 45.44 33.93 33.32 70.28 47.26 33.63 0.26 0.19 0.14 -0.49 -0.78 Matched[1772]
YER141W COX15 "Protein required for the hydroxylation of heme O to form heme A, which is an essential prosthetic group for cytochrome c oxidase" Verified chr5:453454-454914 453454-454914 98.7% 488.75 734.16 605.22 653.75 881.13 743.87 611.46 629.48 812.50 2.26 2.56 3.37 0.37 0.64 Matched[1773]
YER142C MAG1 3-methyl-adenine DNA glycosylase involved in protecting DNA against alkylating agents; initiates base excision repair by removing damaged bases to create abasic sites that are subsequently repaired Verified chr5:455141-456031 455141-456031 99.3% 106.26 84.79 119.83 106.26 482.71 264.53 95.53 113.05 373.62 0.35 0.46 1.55 1.72 0.79 Matched[1774]
YER143W DDI1 "DNA damage-inducible v-SNARE binding protein, contains a ubiquitin-associated (UBA) domain, may act as a negative regulator of constitutive exocytosis, may play a role in S-phase checkpoint control" Verified chr5:456314-457600 456314-457600 98.7% 122.04 111.80 147.23 120.46 273.21 197.62 116.92 133.85 235.42 0.43 0.54 0.98 0.81 1.11 Matched[1775]
YER144C UBP5 "Putative ubiquitin-specific protease, closest paralog of Doa4p but has no functional overlap; concentrates at the bud neck" Verified chr5:457801-460218 457801-460218 98.9% 74.88 63.59 61.49 44.34 97.05 75.30 69.23 52.92 86.17 0.26 0.21 0.36 0.70 0.48 Matched[1776]
YER145C FTR1 High affinity iron permease involved in the transport of iron across the plasma membrane; forms complex with Fet3p; expression is regulated by iron Verified chr5:460521-461735 460521-461735 98.7% 808.06 441.14 582.07 397.78 247.67 124.25 624.60 489.92 185.96 2.31 1.99 0.77 -1.40 -0.95 Frag>80[1777,1778]
YER146W LSM5 "Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA" Verified chr5:462580-462861 462580-462861 98.2% 790.85 631.96 657.24 639.18 859.46 422.51 711.41 648.21 640.99 2.63 2.63 2.66 -0.02 -0.74 Matched[1779]
YER145C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified ORF LSM5/YER146W" Dubious chr5:462381-462818 462381-462818 98.2% 446.30 364.94 423.05 385.86 543.92 248.72 405.62 404.46 396.32 1.50 1.64 1.64 -0.03 NaN Matched[1779]
YER147C SCC4 "Subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for the loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during double-strand break repair via phosphorylated histone H2AX" Verified chr5:462963-464837 462963-464837 99.0% 74.87 60.33 54.40 41.47 43.63 23.16 67.60 47.94 33.40 0.25 0.19 0.14 -0.52 -0.28 Matched[1780]
YER148W SPT15 "TATA-binding protein, general transcription factor that interacts with other factors to form the preinitiation complex at promoters, essential for viability" Verified chr5:465298-466020 465298-466020 98.6% 927.39 700.11 796.91 711.33 548.58 404.07 813.75 754.12 476.32 3.00 3.06 1.97 -0.66 -0.46 Matched[1781]
YER147C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr5:465198-465608 465198-465608 98.5% 718.74 597.72 644.64 600.19 466.81 328.50 658.23 622.41 397.65 2.43 2.53 1.65 -0.65 NaN Matched[1781]
YER148W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr5:466180-466758 466180-466758 99.1% 128.99 115.05 130.74 85.42 144.68 74.96 122.02 108.08 109.82 0.45 0.44 0.46 0.02 NaN Covered/w/another[1782]
YER149C PEA2 "Coiled-coil polarisome protein required for polarized morphogenesis, cell fusion, and low affinity Ca2+ influx; forms polarisome complex with Bni1p, Bud6p, and Spa2p; localizes to sites of polarized growth" Verified chr5:466203-467465 466203-467465 99.0% 110.37 92.77 106.37 68.78 119.16 65.58 101.57 87.57 92.37 0.37 0.36 0.38 0.08 0.31 Matched[1782]
YER150W SPI1 "GPI-anchored, serine/threonine rich cell wall protein of unknown function; basal expression requires Msn2p/Msn4p; expression is induced under conditions of stress and during the diauxic shift; similar to Sed1p" Verified chr5:468365-468811 468365-468811 99.0% 36.15 198.81 106.18 106.18 7846.37 6994.63 117.48 106.18 7420.50 0.43 0.43 30.75 6.13 4.09 Matched[1784]
YER151C UBP3 Ubiquitin-specific protease that interacts with Bre5p to co-regulate anterograde and retrograde transport between endoplasmic reticulum and Golgi compartments; inhibitor of gene silencing; cleaves ubiquitin fusions but not polyubiquitin Verified chr5:469681-472419 469681-472419 99.0% 239.69 219.41 193.23 185.49 198.39 217.57 229.55 189.36 207.98 0.85 0.77 0.86 0.14 0.43 Covered/w/another[1786]
YER152W-A "Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr5:473480-474046 473480-474046 98.8% 196.43 166.07 189.29 142.86 167.86 146.43 181.25 166.07 157.14 0.67 0.67 0.65 -0.08 NaN Covered/w/another[1786]
YER152C Putative protein of unknown function; shares amino acid similarity with the aminotransferases Aro8p and Aro9p; YER152C is not an essential gene Uncharacterized chr5:472652-473983 472652-473983 98.6% 230.03 247.55 191.95 187.38 254.40 171.38 238.79 189.66 212.89 0.88 0.77 0.88 0.17 0.24 Covered/w/another[1786]
YER153C PET122 "Mitochondrial translational activator specific for the COX3 mRNA, acts together with Pet54p and Pet494p; located in the mitochondrial inner membrane" Verified chr5:474036-474800 474036-474800 98.3% 71.78 81.09 58.49 37.22 42.54 23.93 76.44 47.86 33.23 0.28 0.19 0.14 -0.53 -0.35 Covered/w/another[1786]
YER154W OXA1 "Mitochondrial inner membrane insertase, mediates the insertion of both mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane, interacts with mitochondrial ribosomes; conserved from bacteria to animals" Verified chr5:475015-476223 475015-476223 98.9% 334.68 332.17 357.27 310.42 273.60 192.44 333.43 333.84 233.02 1.23 1.36 0.97 -0.52 -0.21 Matched[1787]
YER155C BEM2 Rho GTPase activating protein (RhoGAP) involved in the control of cytoskeleton organization and cellular morphogenesis; required for bud emergence Verified chr5:476340-482843 476340-482843 99.1% 201.20 226.49 177.00 172.66 98.82 135.27 213.85 174.83 117.05 0.79 0.71 0.48 -0.58 -0.16 Frag>80[1788,1789,1790]
YER156C Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus Uncharacterized chr5:483320-484336 483320-484336 98.9% 579.81 404.77 544.01 438.59 123.32 43.76 492.29 491.30 83.54 1.82 1.99 0.35 -2.56 -2.26 Frag>80[1790,1791]
YER157W COG3 "Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" Verified chr5:484783-487188 484783-487188 99.0% 99.05 110.38 87.72 82.68 114.16 94.01 104.72 85.20 104.09 0.39 0.35 0.43 0.29 0.56 Matched[1792]
YER158C "Protein of unknown function, has similarity to Afr1p; potentially phosphorylated by Cdc28p" Uncharacterized chr5:488852-490573 488852-490573 96.9% 80.30 145.63 80.30 73.71 134.84 129.44 112.96 77.01 132.14 0.42 0.31 0.55 0.78 1.18 Covered[1794]
YER158W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr5:491482-491697 491482-491697 99.5% 898.20 893.54 795.81 772.54 944.74 414.19 895.87 784.18 679.46 3.31 3.18 2.82 -0.21 NaN Matched[1795]
YER159C BUR6 Subunit of a heterodimeric NC2 transcription regulator complex with Ncb2p; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2alpha Verified chr5:491525-491953 491525-491953 99.2% 925.61 925.61 791.70 836.34 977.29 512.14 925.61 814.02 744.71 3.42 3.30 3.09 -0.13 -0.41 Frag>80[1795,1796,1797]
YER161C SPT2 "Protein involved in negative regulation of transcription; required for RNA polyadenylation; exhibits regulated interactions with both histones and SWI-SNF components, has similarity to mammalian HMG1 proteins" Verified chr5:499342-500343 499342-500343 99.4% 233.05 267.20 239.08 222.00 199.90 145.66 250.13 230.54 172.78 0.92 0.94 0.72 -0.42 0.02 Matched[1800]
YER162C RAD4 Protein that recognizes and binds damaged DNA (with Rad23p) during nucleotide excision repair; subunit of Nuclear Excision Repair Factor 2 (NEF2); homolog of human XPC protein Verified chr5:500625-502889 500625-502889 99.4% 53.29 51.07 60.39 54.18 83.93 80.37 52.18 57.28 82.15 0.19 0.23 0.34 0.52 0.97 Matched[1801]
YER163C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus Uncharacterized chr5:503079-503777 503079-503777 98.9% 136.00 192.43 167.83 143.24 554.14 329.88 164.22 155.53 442.01 0.61 0.63 1.83 1.51 1.59 Frag>80[1802,1803]
YER164W CHD1 "Nucleosome remodeling factor that functions in regulation of transcription elongation; contains a chromo domain, a helicase domain and a DNA-binding domain; component of both the SAGA and SILK complexes" Verified chr5:505387-509793 505387-509793 98.4% 170.39 158.17 148.95 125.20 55.80 68.02 164.28 137.07 61.91 0.61 0.56 0.26 -1.15 -0.37 Matched[1805]
YER165W PAB1 "Poly(A) binding protein, part of the 3'-end RNA-processing complex, mediates interactions between the 5' cap structure and the 3' mRNA poly(A) tail, involved in control of poly(A) tail length, interacts with translation factor eIF-4G" Verified chr5:510368-512101 510368-512101 98.7% 3003.95 2545.08 2828.58 2736.81 648.84 871.55 2774.51 2782.70 760.19 10.24 11.30 3.15 -1.87 -1.75 Matched[1807]
YER166W DNF1 "Aminophospholipid translocase (flippase) that localizes primarily to the plasma membrane; contributes to endocytosis, protein transport and cell polarity; type 4 P-type ATPase" Verified chr5:512739-517454 512739-517454 98.7% 154.69 172.95 135.35 131.92 82.93 101.41 163.82 133.63 92.17 0.60 0.54 0.38 -0.54 0.18 Covered/w/another[1808]
YER165C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene DNF1/YER166W" Dubious chr5:512622-512978 512622-512978 98.7% 62.43 82.29 36.89 76.61 39.73 85.13 72.36 56.75 62.43 0.27 0.23 0.26 0.14 NaN Covered/w/another[1808]
YER167W BCK2 "Protein rich in serine and threonine residues involved in protein kinase C signaling pathway, which controls cell integrity; overproduction suppresses pkc1 mutations" Verified chr5:518211-520766 518211-520766 98.9% 147.62 157.91 145.64 154.75 131.00 131.00 152.77 150.20 131.00 0.56 0.61 0.54 -0.20 0.41 Covered/w/another[1808]
YER168C CCA1 "ATP (CTP):tRNA-specific tRNA nucleotidyltransferase; different forms targeted to the nucleus, cytosol, and mitochondrion are generated via the use of multiple transcriptional and translational start sites" Verified chr5:521024-522664 521024-522664 99.2% 151.15 119.20 112.44 86.64 80.49 58.37 135.18 99.54 69.43 0.50 0.40 0.29 -0.52 -0.38 Covered/w/another[1808]
YER169W RPH1 JmjC domain-containing histone demethylase which can specifically demethylate H3K36 tri- and dimethyl modification states; transcriptional repressor of PHR1; Rph1p phosphorylation during DNA damage is under control of the MEC1-RAD53 pathway Verified chr5:523364-525754 523364-525754 98.8% 95.69 115.17 76.21 69.86 135.92 129.99 105.43 73.04 132.95 0.39 0.30 0.55 0.86 1.45 Covered/w/another[1809]
YER170W ADK2 "Mitochondrial adenylate kinase, catalyzes the reversible synthesis of GTP and AMP from GDP and ADP; may serve as a back-up for synthesizing GTP or ADP depending on metabolic conditions; 3' sequence of ADK2 varies with strain background" Verified chr5:525969-526646 525969-526646 98.6% 122.60 110.64 116.62 133.07 128.58 80.74 116.62 124.84 104.66 0.43 0.51 0.43 -0.25 0.05 Covered/w/another[1809]
YER171W RAD3 "5' to 3' DNA helicase, involved in nucleotide excision repair and transcription; subunit of RNA polymerase II transcription initiation factor TFIIH; subunit of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPD protein" Verified chr5:527077-529413 527077-529413 98.8% 138.22 124.35 94.02 92.72 50.69 30.76 131.28 93.37 40.73 0.48 0.38 0.17 -1.20 -0.60 Covered/w/another[1809]
YER172C BRR2 RNA-dependent ATPase RNA helicase (DEIH box); required for disruption of U4/U6 base-pairing in native snRNPs to activate the spliceosome for catalysis; homologous to human U5-200kD Verified chr5:529525-536016 529525-536016 99.2% 72.34 63.49 60.69 50.60 29.96 40.20 67.91 55.65 35.08 0.25 0.23 0.15 -0.67 -0.14 Covered/w/another[1809]
YER173W RAD24 "Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; subunit of a clamp loader that loads Rad17p-Mec3p-Ddc1p onto DNA; homolog of human and S. pombe Rad17 protein" Verified chr5:536295-538274 536295-538274 98.7% 72.12 68.54 59.85 48.59 35.29 18.41 70.33 54.22 26.85 0.26 0.22 0.11 -1.01 -0.37 Matched[1810]
YER172C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr5:536270-536650 536270-536650 98.8% 37.21 42.52 34.55 50.49 29.23 13.29 39.86 42.52 21.26 0.15 0.17 0.09 -1.00 NaN Covered/w/another[1810]
YER174C GRX4 Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx3p and Grx5p; protects cells from oxidative damage Verified chr5:538429-539163 538429-539163 99.0% 211.54 251.37 217.03 244.51 162.09 114.01 231.46 230.77 138.05 0.85 0.94 0.57 -0.74 -1.23 Covered/w/another[1811]
YER175C TMT1 "Trans-aconitate methyltransferase, cytosolic enzyme that catalyzes the methyl esterification of 3-isopropylmalate, an intermediate of the leucine biosynthetic pathway, and trans-aconitate, which inhibits the citric acid cycle" Verified chr5:539459-540358 539459-540358 99.1% 72.90 190.66 96.45 97.57 182.81 191.78 131.78 97.01 187.30 0.49 0.39 0.78 0.95 1.46 Covered/w/another[1811]
YER175W-A "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr5:540645-540809 540645-540809 98.9% 61.30 73.56 85.82 42.91 55.17 24.52 67.43 64.37 39.85 0.25 0.26 0.17 -0.69 NaN Covered/w/another[1811]
YER176W ECM32 "DNA dependent ATPase/DNA helicase belonging to the Dna2p- and Nam7p-like family of helicases that is involved in modulating translation termination; interacts with the translation termination factors, localized to polysomes" Verified chr5:541685-545050 541685-545050 98.5% 150.57 133.07 109.54 97.16 85.09 91.73 141.82 103.35 88.41 0.52 0.42 0.37 -0.23 -0.12 Matched[1812]
YER177W BMH1 "14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling" Verified chr5:545606-546409 545606-546409 93.9% 8058.72 9834.98 7569.95 7277.22 13101.38 9988.63 8946.85 7423.59 11545.01 33.03 30.13 47.83 0.64 0.30 Matched[1813]
YER178W PDA1 "E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex, catalyzes the direct oxidative decarboxylation of pyruvate to acetyl-CoA; phosphorylated; regulated by glucose" Verified chr5:546812-548074 546812-548074 98.6% 1804.54 2115.19 1866.35 1857.52 1957.86 1771.62 1959.86 1861.93 1864.74 7.23 7.56 7.73 0.00 -0.14 Matched[1814]
YER179W DMC1 Meiosis-specific protein required for repair of double-strand breaks and pairing between homologous chromosomes; homolog of Rad51p and the bacterial RecA protein Verified chr5:548416-549512 548416-548547,548640-549512 98.6% 26.24 60.56 28.26 22.20 69.64 35.32 43.40 25.23 52.48 0.16 0.10 0.22 1.06 1.16 Frag>80[1815,1816]
YER180C ISC10 "Protein required for sporulation, transcript is induced 7.5 hours after induction of meiosis, expected to play significant role in the formation of reproductive cells" Verified chr5:549719-550522 549719-550522 99.2% 179.23 167.95 157.92 112.80 135.36 87.73 173.59 135.36 111.55 0.64 0.55 0.46 -0.28 0.06 Matched[1817]
YER180C-A SLO1 "Protein interacting with Arl3p, which is a GTPase of the Ras superfamily involved in vesicle-tethering at the Golgi; putative ortholog of human SCOCO" Verified chr5:550860-551117 550860-551117 99.4% 140.33 101.35 85.76 58.47 113.04 101.35 120.84 72.11 107.20 0.45 0.29 0.44 0.57 NaN Covered/w/another[1817]
YER181C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative data; extensively overlaps a Ty1 LTR; protein product is detected in highly purified mitochondria in high-throughput studies" Dubious chr5:551468-551791 551468-551791 97.0% 0.00 0.00 0.00 0.00 12.73 0.00 0.00 0.00 6.37 0.00 0.00 0.03 Inf 1.85
YER182W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr5:552520-553254 552520-553254 98.7% 157.17 217.83 231.62 208.18 517.00 341.91 187.50 219.90 429.46 0.69 0.89 1.78 0.97 0.83 Matched[1818]
YER183C FAU1 "5,10-methenyltetrahydrofolate synthetase, involved in folic acid biosynthesis" Verified chr5:553329-553964 553329-553964 99.1% 160.32 133.33 192.06 144.44 169.84 119.05 146.83 168.25 144.44 0.54 0.68 0.60 -0.22 -0.10 Matched[1819]
YER184C "Putative zinc cluster protein; deletion confers sensitivity to Calcufluor white, and prevents growth on glycerol or lactate as sole carbon source" Uncharacterized chr5:556291-558675 556291-558675 99.1% 32.57 30.03 16.49 15.23 25.80 29.61 31.30 15.86 27.70 0.12 0.06 0.11 0.80 0.65 Overlap[1820]
YER185W "Plasma membrane protein involved in protoporphyrin uptake; similar in sequence to RSB1, which is involved in sphingoid long-chain base release" Uncharacterized chr5:559449-560360 559449-560360 99.1% 7.74 13.27 5.53 4.42 1.11 3.32 10.51 4.98 2.21 0.04 0.02 0.01 -1.17 -0.80
YER186C Putative protein of unknown function Uncharacterized chr5:561700-562620 561700-562620 99.1% 256.30 284.78 248.63 210.30 143.48 81.05 270.54 229.46 112.27 1.00 0.93 0.47 -1.03 -1.14 Matched[1822]
YER187W Putative protein of unknown function; induced in respiratory-deficient cells Uncharacterized chr5:566225-566650 566225-566650 98.2% 119.51 179.26 141.02 119.51 74.10 40.63 149.39 130.27 57.36 0.55 0.53 0.24 -1.18 -1.07 Matched[1823]
YER188W Hypothetical protein Dubious chr5:568035-568754 568035-568754 98.6% 74.62 588.53 109.82 136.57 228.09 218.23 331.57 123.20 223.16 1.22 0.50 0.92 0.86 1.37 Matched[1825]
YER188C-A Putative protein of unknown function Uncharacterized chr5:569603-569902 569603-569902 11.0% 30.30 30.30 0.00 0.00 0.00 0.00 30.30 0.00 0.00 0.11 0.00 0.00 NaN NaN
YER189W Putative protein of unknown function Uncharacterized chr5:571150-571518 571150-571518 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.17
YER190W YRF1-2 "Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p" Verified chr5:571475-576520 571475-576520 0.2% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.20
YER190C-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr5:574799-575374 574799-575374 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YER190C-B "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr5:575675-576157 575675-576157 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YFL068W Putative protein of unknown function Uncharacterized chr6:53-535 53-535 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.44
YFL067W "Protein of unknown function, down-regulated at low calcium levels" Uncharacterized chr6:836-1363 836-1363 7.7% 0.00 0.00 73.77 73.77 24.59 73.77 0.00 73.77 49.18 0.00 0.30 0.20 -0.58 -0.03
YFL066C Helicase-like protein encoded within the telomeric Y' element Uncharacterized chr6:1437-2615 1437-2615 0.4% 0.00 377.95 188.98 0.00 377.95 188.98 188.98 94.49 283.46 0.70 0.38 1.17 1.58 0.59 Frag<80[1828]
YFL065C Putative protein of unknown function Uncharacterized chr6:3030-3338 3030-3338 1.0% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN -0.12
YFL064C Putative protein of unknown function Uncharacterized chr6:3322-3846 3322-3846 0.8% 0.00 228.57 0.00 0.00 0.00 0.00 114.29 0.00 0.00 0.42 0.00 0.00 NaN -0.25
YFL063W "Dubious open reading frame, based on available experimental and comparative sequence data" Dubious chr6:5066-5521 5066-5521 31.2% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN -0.18
YFL062W COS4 "Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" Verified chr6:6426-7565 6426-7565 6.0% 14.74 44.23 0.00 0.00 14.74 0.00 29.48 0.00 7.37 0.11 0.00 0.03 Inf 0.17
YFL061W Protein whose expression is induced by DNA damage Uncharacterized chr6:9545-10222 9545-10222 0.6% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.39
YFL060C SNO3 "Protein of unknown function, nearly identical to Sno2p; expression is induced before the diauxic shift and also in the absence of thiamin" Verified chr6:10301-10969 10301-10969 1.4% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.52
YFL059W SNZ3 "Member of a stationary phase-induced gene family; transcription of SNZ2 is induced prior to diauxic shift, and also in the absence of thiamin in a Thi2p-dependent manner; forms a coregulated gene pair with SNO3" Verified chr6:11363-12259 11363-12259 5.6% 119.30 0.00 59.65 39.77 39.77 0.00 59.65 49.71 19.88 0.22 0.20 0.08 -1.32 -0.14 Frag<80[1829]
YFL058W THI5 "Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP); member of a subtelomeric gene family including THI5, THI11, THI12, and THI13" Verified chr6:12929-13951 12929-13951 0.9% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.80
YFL057C AAD16 Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role Verified chr6:14305-14763 14305-14763 9.4% 93.02 162.79 116.28 139.53 69.77 23.26 127.91 127.91 46.51 0.47 0.52 0.19 -1.46 0.20 Frag<80[1830]
YFL056C AAD6 "Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase, involved in the oxidative stress response" Verified chr6:14793-15431 14793-15431 77.4% 82.93 68.77 70.79 44.50 64.72 46.52 75.85 57.64 55.62 0.28 0.23 0.23 -0.05 0.19 Frag<80[1830]
YFL055W AGP3 "Low-affinity amino acid permease, may act to supply the cell with amino acids as nitrogen source in nitrogen-poor conditions; transcription is induced under conditions of sulfur limitation" Verified chr6:17004-18680 17004-18680 98.8% 13.89 15.70 10.87 13.89 36.23 26.57 14.79 12.38 31.40 0.05 0.05 0.13 1.34 1.52 Matched[1832]
YFL054C Putative channel-like protein; similar to Fps1p; mediates passive diffusion of glycerol in the presence of ethanol Uncharacterized chr6:20847-22787 20847-22787 99.0% 35.90 59.32 68.16 68.16 95.74 88.46 47.61 68.16 92.10 0.18 0.28 0.38 0.43 0.90 Covered/w/another[1834]
YFL053W DAK2 "Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress adaptation" Verified chr6:23423-25198 23423-25198 98.4% 10.30 15.45 18.88 19.45 28.60 64.65 12.87 19.16 46.62 0.05 0.08 0.19 1.28 0.70 Covered/w/another[1834]
YFL052W "Putative zinc cluster protein that contains a DNA binding domain; null mutant sensitive to calcofluor white, low osmolarity and heat, suggesting a role for YFL052Wp in cell wall integrity" Uncharacterized chr6:28232-29629 28232-29629 98.4% 17.44 29.07 24.71 19.63 23.26 22.53 23.26 22.17 22.90 0.09 0.09 0.09 0.05 -0.02 Overlap[1835]
YFL051C Putative protein of unknown function; YFL051C is not an essential gene Uncharacterized chr6:30058-30540 30058-30540 98.6% 31.49 46.18 54.57 44.08 33.58 37.78 38.83 49.33 35.68 0.14 0.20 0.15 -0.47 0.24 Covered[1835]
YFL050C ALR2 Probable Mg(2+) transporter; overexpression confers increased tolerance to Al(3+) and Ga(3+) ions Verified chr6:33272-35848 33272-35848 96.1% 42.38 55.30 31.08 29.47 33.10 31.08 48.84 30.27 32.09 0.18 0.12 0.13 0.08 0.71 Matched[1836]
YFL049W SWP82 Member of the SWI/SNF chromatin remodeling complex in which it plays an as yet unidentified role; has identifiable counterparts in closely related yeast species; abundantly expressed in many growth conditions; paralog of Npl6p Verified chr6:36803-38674 36803-38674 98.7% 89.82 104.43 101.19 88.20 112.01 83.87 97.13 94.69 97.94 0.36 0.38 0.41 0.05 0.27 Matched[1837]
YFL048C EMP47 "Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport" Verified chr6:38843-40180 38843-40180 99.3% 361.39 301.16 307.93 313.96 371.93 233.40 331.27 310.95 302.66 1.22 1.26 1.25 -0.04 0.36 Matched[1838]
YFL047W RGD2 GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p Verified chr6:40421-42565 40421-42565 98.7% 161.58 171.97 180.48 135.59 121.42 102.52 166.77 158.03 111.97 0.62 0.64 0.46 -0.50 0.11 Matched[1839]
YFL046W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr6:42815-43438 42815-43438 98.4% 192.13 275.17 205.16 156.31 345.18 180.73 233.65 180.73 262.96 0.86 0.73 1.09 0.54 -0.39 Matched[1840]
YFL045C SEC53 "Phosphomannomutase, involved in synthesis of GDP-mannose and dolichol-phosphate-mannose; required for folding and glycosylation of secretory proteins in the ER lumen" Verified chr6:43628-44392 43628-44392 99.0% 2992.90 2237.41 2777.61 2592.70 1250.78 970.78 2615.16 2685.16 1110.78 9.65 10.90 4.60 -1.27 -1.80 Frag>80[1841,1842]
YFL044C OTU1 Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p; may contribute to regulation of protein degradation by deubiquitylating substrates that have been ubiquitylated by Ufd2p; member of the Ovarian Tumor (OTU) family Verified chr6:44655-45560 44655-45560 98.9% 100.40 87.02 105.98 111.56 315.72 247.66 93.71 108.77 281.69 0.35 0.44 1.17 1.37 1.98 Matched[1843]
YFL042C Putative protein of unknown function; YFL042C is not an essential gene Uncharacterized chr6:45720-47744 45720-47744 99.0% 80.81 118.72 97.77 100.27 212.01 203.53 99.77 99.02 207.77 0.37 0.40 0.86 1.07 1.50 Covered/w/another[1844]
YFL041W-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr6:48734-48925 48734-48925 99.0% 42.11 105.26 36.84 47.37 110.53 73.68 73.68 42.11 92.11 0.27 0.17 0.38 1.13 NaN Covered/w/another[1844]
YFL041W FET5 "Multicopper oxidase, integral membrane protein with similarity to Fet3p; may have a role in iron transport" Verified chr6:49139-51007 49139-51007 98.7% 182.59 145.21 202.10 184.22 121.37 130.58 163.90 193.16 125.97 0.61 0.78 0.52 -0.62 -0.12 Matched[1845]
YFL040W "Putative transporter, member of the sugar porter family; YFL040W is not an essential gene" Uncharacterized chr6:51350-52972 51350-52972 98.8% 17.45 10.60 18.08 13.09 21.19 9.97 14.02 15.58 15.58 0.05 0.06 0.06 0.00 -0.11 Frag<80[1846]
YFL039C ACT1 "Actin, structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions" Verified chr6:53260-54695 53260-54377,54686-54695 98.5% 7987.10 7710.88 7841.34 7597.51 8078.88 7025.27 7848.99 7719.43 7552.07 28.97 31.33 31.29 -0.03 -0.46 Frag>80[1846,1847,1848,1849]
YFL038C YPT1 "Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p)" Verified chr6:55365-55985 55365-55985 98.6% 1596.63 1697.84 1714.17 1568.87 2427.59 1590.10 1647.23 1641.52 2008.84 6.08 6.66 8.32 0.29 -0.21 Matched[1850]
YFL037W TUB2 "Beta-tubulin; associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer, which polymerizes to form microtubules" Verified chr6:56335-57708 56335-57708 98.5% 1628.91 1591.97 1591.23 1517.36 1328.98 1208.57 1610.44 1554.30 1268.78 5.94 6.31 5.26 -0.29 -0.11 Matched[1851]
YFL036W RPO41 Mitochondrial RNA polymerase; single subunit enzyme similar to those of T3 and T7 bacteriophages; requires a specificity subunit encoded by MTF1 for promoter recognition Verified chr6:58781-62836 58781-62836 98.8% 114.31 126.04 140.77 154.25 129.29 177.96 120.18 147.51 153.62 0.44 0.60 0.64 0.06 0.37 Frag>80[1852,1853]
YFL034C-B MOB2 "Component of the RAM signaling network, localizes and activates the Ace2p in the daughter cell nucleus to direct daughter cell-specific transcription of several genes involved in cell separation; Mob1p-like protein" Verified chr6:63015-63992 63015-63858,63973-63992 98.8% 195.57 147.56 189.71 166.29 92.51 80.80 171.56 178.00 86.66 0.63 0.72 0.36 -1.04 -0.54 Matched[1854]
YFL034C-A RPL22B "Protein component of the large (60S) ribosomal subunit, has similarity to Rpl22Ap and to rat L22 ribosomal protein" Verified chr6:64242-64931 64242-64598,64920-64931 99.0% 1355.08 1147.03 1043.00 487.28 166.99 43.80 1251.06 765.14 105.40 4.62 3.11 0.44 -2.86 -2.81 Matched[1855]
YFL034W "Putative integral membrane protein that interacts with Rpp0p, which is a component of the ribosomal stalk" Uncharacterized chr6:65475-68696 65475-68696 98.5% 94.23 93.91 92.02 82.88 80.36 84.77 94.07 87.45 82.57 0.35 0.35 0.34 -0.08 0.47 Matched[1856]
YFL033C RIM15 "Glucose-repressible protein kinase involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; substrate of Pho80p-Pho85p kinase" Verified chr6:69113-74425 69113-74425 98.6% 109.95 136.67 104.03 96.21 88.38 136.48 123.31 100.12 112.43 0.46 0.41 0.47 0.17 0.83 Matched[1857]
YFL032W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene HAC1/YFL031W; YFL032W is not an essential gene" Dubious chr6:74870-75190 74870-75190 99.2% 455.44 530.82 458.58 446.01 716.14 468.00 493.13 452.30 592.07 1.82 1.84 2.45 0.39 1.05 Overlap[1858]
YFL031W HAC1 "bZIP transcription factor (ATF/CREB1 homolog) that regulates the unfolded protein response, via UPRE binding, and membrane biogenesis; ER stress-induced splicing pathway utilizing Ire1p, Trl1p and Ada5p facilitates efficient Hac1p synthesis" Verified chr6:75177-76145 75177-75837,76090-76145 98.3% 2677.54 3176.74 2691.72 2599.54 4081.55 2965.43 2927.14 2645.63 3523.49 10.81 10.74 14.60 0.41 -0.71 Matched[1858]
YFL031C-A "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps HAC1/YFL031W; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr6:76012-76113 76012-76113 99.0% 3040.86 3595.54 2862.57 2822.95 5249.69 3189.43 3318.20 2842.76 4219.56 12.25 11.54 17.48 0.57 NaN Covered/w/another[1858]
YFL030W AGX1 "Alanine:glyoxylate aminotransferase (AGT), catalyzes the synthesis of glycine from glyoxylate, which is one of three pathways for glycine biosynthesis in yeast; has similarity to mammalian and plant alanine:glyoxylate aminotransferases" Verified chr6:76829-77986 76829-77986 98.5% 23.66 58.71 45.57 38.56 135.83 69.23 41.19 42.06 102.53 0.15 0.17 0.42 1.29 0.98 Covered/w/another[1859]
YFL029C CAK1 "Cyclin-dependent kinase-activating kinase required for passage through the cell cycle, phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases" Verified chr6:78053-79159 78053-79159 99.1% 101.17 107.55 123.04 98.44 166.79 97.52 104.36 110.74 132.16 0.39 0.45 0.55 0.26 0.52 Covered/w/another[1859]
YFL028C CAF16 "Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation; putative ABC ATPase; interacts with Ssn2p, Ssn3p, and Ssn8p" Verified chr6:79342-80211 79342-80211 99.3% 216.52 231.57 196.84 181.78 195.68 130.84 224.04 189.31 163.26 0.83 0.77 0.68 -0.21 -0.57 Covered/w/another[1859]
YFL027C GYP8 "GTPase-activating protein for yeast Rab family members; Ypt1p is the preferred in vitro substrate but also acts on Sec4p, Ypt31p and Ypt32p; involved in the regulation of ER to Golgi vesicle transport" Verified chr6:80417-81910 80417-81910 99.2% 134.89 169.96 117.36 99.82 90.38 62.72 152.43 108.59 76.55 0.56 0.44 0.32 -0.50 -0.21 Matched[1860]
YFL026W STE2 Receptor for alpha-factor pheromone; seven transmembrane-domain GPCR that interacts with both pheromone and a heterotrimeric G protein to initiate the signaling response that leads to mating between haploid a and alpha cells Verified chr6:82578-83873 82578-83873 99.1% 2836.45 3649.53 2636.29 2285.05 1066.20 576.32 3242.99 2460.67 821.26 11.97 9.99 3.40 -1.58 -1.57 Frag>80[1861,1862]
YFL025C BST1 "GPI inositol deacylase of the ER that negatively regulates COPII vesicle formation, prevents production of vesicles with defective subunits, required for proper discrimination between resident ER proteins and Golgi-bound cargo molecules" Verified chr6:84143-87232 84143-87232 99.0% 72.25 75.52 44.46 43.81 50.35 50.35 73.89 44.14 50.35 0.27 0.18 0.21 0.19 -0.15 Matched[1863]
YFL024C EPL1 "Component of NuA4, which is an essential histone H4/H2A acetyltransferase complex; homologous to Drosophila Enhancer of Polycomb" Verified chr6:87845-90343 87845-90343 98.9% 150.56 146.51 121.01 95.51 147.32 121.01 148.53 108.26 134.17 0.55 0.44 0.56 0.31 0.63 Matched[1864]
YFL023W BUD27 "Protein involved in bud-site selection, nutrient signaling, and gene expression controlled by the TOR kinase; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern" Verified chr6:90984-93374 90984-93374 95.4% 113.52 81.08 69.69 50.84 5.70 6.14 97.30 60.27 5.92 0.36 0.24 0.02 -3.35 -2.47 Matched[1865]
YFL022C FRS2 "Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar" Verified chr6:93497-95008 93497-95008 98.7% 755.36 638.74 756.70 609.25 245.98 244.64 697.05 682.98 245.31 2.57 2.77 1.02 -1.48 -0.79 Matched[1866]
YFL021W GAT1 Transcriptional activator of genes involved in nitrogen catabolite repression; contains a GATA-1-type zinc finger DNA-binding motif; activity and localization regulated by nitrogen limitation and Ure2p Verified chr6:95964-97496 95964-97496 99.0% 237.17 292.51 237.83 206.21 156.80 145.60 264.84 222.02 151.20 0.98 0.90 0.63 -0.55 0.15 Frag>80[1868]
YFL021C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr6:95759-96613 95759-96613 98.9% 146.66 150.21 153.76 115.91 91.07 105.26 148.43 134.83 98.17 0.55 0.55 0.41 -0.46 NaN Frag<80[1867]
YFL020C PAU5 "Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme" Verified chr6:99225-99593 99225-99593 35.2% 0.00 7.70 0.00 0.00 61.58 46.18 3.85 0.00 53.88 0.01 0.00 0.22 Inf 1.19 Overlap[1870]
YFL019C Dubious open reading frame unlikely to encode a protein; YFL019C is not an essential gene Dubious chr6:100246-100599 100246-100599 98.9% 8.57 11.42 11.42 11.42 65.68 45.69 10.00 11.42 55.69 0.04 0.05 0.23 2.29 0.89 Covered[1870]
YFL018C LPD1 "Dihydrolipoamide dehydrogenase, the lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase multi-enzyme complexes" Verified chr6:101622-103121 101622-103121 99.1% 911.87 885.62 921.29 953.59 1043.77 1012.81 898.75 937.44 1028.29 3.32 3.81 4.26 0.13 0.35 Frag>80[1871,1872]
YFL017W-A SMX2 "Core Sm protein Sm G; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Sme1p, and Smx3p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm G" Verified chr6:103693-103926 103693-103926 98.7% 337.78 233.85 225.19 212.20 259.83 134.25 285.82 218.69 197.04 1.06 0.89 0.82 -0.15 -0.26 Matched[1873]
YFL017C GNA1 "Evolutionarily conserved glucosamine-6-phosphate acetyltransferase required for multiple cell cycle events including passage through START, DNA synthesis, and mitosis; involved in UDP-N-acetylglucosamine synthesis, forms GlcNAc6P from AcCoA" Verified chr6:103977-104456 103977-104456 99.3% 415.46 421.75 365.10 388.18 375.59 253.89 418.60 376.64 314.74 1.55 1.53 1.30 -0.26 -0.48 Matched[1874]
YFL016C MDJ1 Protein involved in folding of mitochondrially synthesized proteins in the mitochondrial matrix; localizes to the mitochondrial inner membrane; member of the DnaJ family of molecular chaperones Verified chr6:104695-106230 104695-106230 98.9% 277.25 278.57 279.23 295.69 3466.67 3238.15 277.91 287.46 3352.41 1.03 1.17 13.89 3.54 2.92 Matched[1875]
YFL015W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr6:106409-106726 106409-106726 97.9% 9.64 6.42 0.00 12.85 61.03 38.54 8.03 6.42 49.79 0.03 0.03 0.21 2.95 NaN Matched[1876]
YFL015C Dubious open reading frame unlikely to encode a protein; partially overlaps dubious ORF YFL015W-A; YFL015C is not an essential gene Dubious chr6:106463-106957 106463-106957 97.6% 8.28 18.63 2.07 14.49 53.83 43.47 13.46 8.28 48.65 0.05 0.03 0.20 2.55 3.61 Frag>80[1876,1877]
YFL014W HSP12 "Plasma membrane localized protein that protects membranes from desiccation; induced by heat shock, oxidative stress, osmostress, stationary phase entry, glucose depletion, oleate and alcohol; regulated by the HOG and Ras-Pka pathways" Verified chr6:107250-107579 107250-107579 98.1% 259.36 2247.78 367.43 484.75 111073.72 54727.90 1253.57 426.09 82900.81 4.63 1.73 343.49 7.60 4.63 Matched[1878]
YFL013W-A "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps IES1/YFL013C; identified by gene-trapping, microarray expression analysis, and genome-wide homology searching" Dubious chr6:107793-108596 107793-108596 99.2% 191.87 220.71 215.70 175.57 170.55 131.68 206.29 195.63 151.11 0.76 0.79 0.63 -0.37 NaN Covered/w/another[1879]
YFL012W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene IES1/YFL013C" Dubious chr6:109804-110178 109804-110178 99.2% 26.89 29.58 34.96 29.58 13.45 18.83 28.24 32.27 16.14 0.10 0.13 0.07 -1.00 0.15 Frag<80[1880]
YFL013C IES1 Subunit of the INO80 chromatin remodeling complex Verified chr6:107846-109924 107846-109924 99.3% 136.16 152.64 141.49 129.38 103.21 107.57 144.40 135.44 105.39 0.53 0.55 0.44 -0.36 0.01 Matched[1879]
YFL012W Putative protein of unknown function; transcribed during sporulation; null mutant exhibits increased resistance to rapamycin Uncharacterized chr6:110641-111087 110641-111087 98.8% 13.59 9.06 4.53 6.79 15.85 2.26 11.32 5.66 9.06 0.04 0.02 0.04 0.68 -0.18 Overlap[1881]
YFL011W HXT10 "Putative hexose transporter, expressed at low levels and expression is repressed by glucose" Verified chr6:112339-113979 112339-113979 98.7% 4.32 9.88 1.85 1.85 8.03 22.24 7.10 1.85 15.13 0.03 0.01 0.06 3.03 1.02
YFL010W-A AUA1 "Protein required for the negative regulation by ammonia of Gap1p, which is a general amino acid permease" Verified chr6:114984-115268 114984-115268 95.1% 663.80 829.75 715.43 545.79 1128.46 789.18 746.77 630.61 958.82 2.76 2.56 3.97 0.60 0.42 Matched[1882]
YFL010C WWM1 "WW domain containing protein of unknown function; binds to Mca1p, a caspase-related protease that regulates H2O2-induced apoptosis; overexpression causes Gi phase growth arrest and clonal death that is suppressed by overexpression of MCA1" Verified chr6:115102-115737 115102-115737 96.8% 683.53 842.65 699.77 599.11 1013.12 910.84 763.09 649.44 961.98 2.82 2.64 3.99 0.57 0.74 Matched[1882]
YFL009W CDC4 "F-box protein required for G1/S and G2/M transition, associates with Skp1p and Cdc53p to form a complex, SCFCdc4, which acts as ubiquitin-protein ligase directing ubiquitination of the phosphorylated CDK inhibitor Sic1p" Verified chr6:116139-118478 116139-118478 77.4% 111.56 107.69 114.32 109.90 133.65 130.33 109.62 112.11 131.99 0.40 0.46 0.55 0.24 0.92 Frag>80[1883,1884]
YFL008W SMC1 "Subunit of the multiprotein cohesin complex, essential protein involved in chromosome segregation and in double-strand DNA break repair; SMC chromosomal ATPase family member, binds DNA with a preference for DNA with secondary structure" Verified chr6:119424-123101 119424-123101 98.6% 168.48 143.66 148.90 142.56 96.79 91.55 156.07 145.73 94.17 0.58 0.59 0.39 -0.63 -0.08 Matched[1885]
YFL007W BLM10 "Proteosome activator subunit; found in association with core particles, with and without the 19S regulatory particle; required for resistance to bleomycin, may be involved in protecting against oxidative damage; similar to mammalian PA200" Verified chr6:123474-129905 123474-129905 98.9% 116.19 85.37 98.89 91.50 86.31 99.52 100.78 95.20 92.92 0.37 0.39 0.38 -0.03 0.31 Frag>80[1886,1887]
YFL005W SEC4 Secretory vesicle-associated Rab GTPase essential for exocytosis; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane Verified chr6:130329-130976 130329-130976 98.4% 921.87 746.28 852.89 802.72 1012.80 780.77 834.07 827.80 896.79 3.08 3.36 3.72 0.12 -0.63 Matched[1888]
YFL004W VTC2 Vacuolar membrane protein involved in vacuolar polyphosphate accumulation; functions as a regulator of vacuolar H+-ATPase activity and vacuolar transporter chaperones; involved in protein localization and non-autophagic vacuolar fusion Verified chr6:131805-134291 131805-134291 98.7% 862.32 942.16 894.50 885.95 279.43 229.33 902.24 890.22 254.38 3.33 3.61 1.05 -1.81 -1.44 Matched[1889]
YFL003C MSH4 "Protein involved in meiotic recombination, required for normal levels of crossing over, colocalizes with Zip2p to discrete foci on meiotic chromosomes, has homology to bacterial MutS protein" Verified chr6:134516-137152 134516-137152 99.3% 8.79 10.70 8.02 6.88 13.37 6.88 9.74 7.45 10.12 0.04 0.03 0.04 0.44 -0.02 Frag<80[1890]
YFL002C SPB4 "Putative ATP-dependent RNA helicase, nucleolar protein required for synthesis of 60S ribosomal subunits at a late step in the pathway; sediments with 66S pre-ribosomes in sucrose gradients" Verified chr6:145109-146929 145109-146929 99.2% 157.81 119.05 112.96 98.56 35.99 16.06 138.43 105.76 26.02 0.51 0.43 0.11 -2.02 -0.57 Matched[1891]
YFL001W DEG1 "Non-essential tRNA:pseudouridine synthase, introduces pseudouridines at position 38 or 39 in tRNA, important for maintenance of translation efficiency and normal cell growth, localizes to both the nucleus and cytoplasm" Verified chr6:147126-148454 147126-148454 98.8% 112.71 92.15 97.48 87.58 44.17 35.03 102.43 92.53 39.60 0.38 0.38 0.16 -1.22 -0.96 Matched[1892]
YFR001W LOC1 Nuclear protein involved in asymmetric localization of ASH1 mRNA; binds double-stranded RNA in vitro; constituent of 66S pre-ribosomal particles Verified chr6:149105-149719 149105-149719 98.2% 491.86 327.91 342.81 286.50 84.46 67.90 409.88 314.66 76.18 1.51 1.28 0.32 -2.05 -2.98 Matched[1893]
YFR002W NIC96 "Component of the nuclear pore complex, required for nuclear pore formation; forms a subcomplex with Nsp1p, Nup57p, and Nup49p" Verified chr6:150011-152530 150011-152530 98.9% 185.87 167.40 140.50 149.74 97.95 88.72 176.63 145.12 93.33 0.65 0.59 0.39 -0.64 -0.23 Matched[1894]
YFR003C YPI1 "Inhibitor of the type I protein phosphatase Glc7p, which is involved in regulation of a variety of metabolic processes; overproduction causes decreased cellular content of glycogen" Verified chr6:152652-153119 152652-153119 99.1% 258.85 334.35 312.78 360.24 1207.98 606.15 296.60 336.51 907.06 1.09 1.37 3.76 1.43 0.96 Matched[1895]
YFR004W RPN11 Metalloprotease subunit of the 19S regulatory particle of the 26S proteasome lid; couples the deubiquitination and degradation of proteasome substrates Verified chr6:153388-154308 153388-154308 98.5% 516.13 404.74 564.65 512.82 1097.33 633.03 460.44 538.74 865.18 1.70 2.19 3.58 0.68 0.42 Matched[1896]
YFR005C SAD1 "Conserved zinc-finger domain protein involved in pre-mRNA splicing, required for assembly of U4 snRNA into the U4/U6 particle" Verified chr6:154522-155868 154522-155868 99.1% 179.07 198.55 130.37 119.88 75.67 61.44 188.81 125.12 68.55 0.70 0.51 0.28 -0.87 -0.50 Matched[1897]
YFR006W Putative X-Pro aminopeptidase; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YFR006W is not an essential gene Uncharacterized chr6:156139-157746 156139-157746 98.8% 394.75 525.71 424.34 421.83 411.12 331.16 460.23 423.09 371.14 1.70 1.72 1.54 -0.19 0.10 Frag>80[1898]
YFR007W Putative protein of unknown function with similarity to pantothenate kinases from other organisms; YFR007W is not an essential gene Uncharacterized chr6:159293-160354 159293-160354 98.9% 73.33 99.04 94.28 80.00 112.38 64.76 86.19 87.14 88.57 0.32 0.35 0.37 0.02 0.02 Covered/w/another[1899]
YFR008W FAR7 "Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway different from the Far1p-dependent pathway; interacts with Far3p, Far8p, Far9p, Far10p, and Far11p" Verified chr6:160529-161194 160529-161194 97.0% 58.82 77.39 77.39 65.01 171.82 95.97 68.11 71.20 133.89 0.25 0.29 0.55 0.91 0.96 Covered/w/another[1899]
YFR009W GCN20 "Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn1p; proposed to stimulate Gcn2p activation by an uncharged tRNA" Verified chr6:162482-164740 162482-164740 98.8% 445.13 388.64 390.89 407.47 290.47 282.85 416.88 399.18 286.66 1.54 1.62 1.19 -0.48 -0.12 Matched[1900]
YFR009W-A "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene YFR009W; identified by expression profiling and mass spectrometry" Dubious chr6:163869-164126 163869-164126 99.1% 504.40 441.84 445.75 508.31 316.72 344.09 473.12 477.03 330.40 1.75 1.94 1.37 -0.53 NaN Covered/w/another[1900]
YFR010W UBP6 "Ubiquitin-specific protease situated in the base subcomplex of the 26S proteasome, releases free ubiquitin from branched polyubiquitin chains; deletion causes hypersensitivity to cycloheximide and other toxic compounds" Verified chr6:165060-166559 165060-166559 98.7% 405.25 422.13 428.89 424.16 692.29 593.68 413.69 426.52 642.99 1.53 1.73 2.66 0.59 0.86 Matched[1901]
YFR010W-A "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the uncharacterized gene YFR011C; identified by expression profiling and mass spectrometry" Dubious chr6:166721-166909 166721-166909 99.6% 329.28 270.86 318.65 302.72 477.98 276.17 300.07 310.69 377.07 1.11 1.26 1.56 0.28 NaN Matched[1902]
YFR011C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YFR011C is not an essential gene" Uncharacterized chr6:166739-167251 166739-167251 99.4% 278.39 211.73 329.36 282.31 429.34 274.46 245.06 305.83 351.90 0.90 1.24 1.46 0.20 0.02 Matched[1902]
YFR012W Putative protein of unknown function Uncharacterized chr6:167881-168489 167881-168489 99.1% 6.62 3.31 8.28 9.94 9.94 14.91 4.97 9.11 12.42 0.02 0.04 0.05 0.45 -0.02
YFR012W-A Putative protein of unknown function; identified by homology Uncharacterized chr6:169216-169302 169216-169302 98.9% 11.63 0.00 11.63 0.00 0.00 0.00 5.81 5.81 0.00 0.02 0.02 0.00 -Inf 0.09
YFR013W IOC3 "Member of a complex (Isw1a) with Isw1p that has nucleosome-stimulated ATPase activity and represses transcription initiation by specific positioning of a promoter proximal dinucleosome; has homology to Esc8p, which is involved in silencing" Verified chr6:169914-172277 169914-172277 98.7% 174.87 135.01 138.87 137.58 88.29 81.01 154.94 138.22 84.65 0.57 0.56 0.35 -0.71 -0.47 Matched[1903]
YFR014C CMK1 "Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to Cmk2p and mammalian Cam Kinase II" Verified chr6:172529-173869 172529-173869 99.3% 211.02 310.90 343.94 367.22 521.92 368.72 260.96 355.58 445.32 0.96 1.44 1.85 0.32 0.41 Matched[1904]
YFR015C GSY1 "Glycogen synthase with similarity to Gsy2p, the more highly expressed yeast homolog; expression induced by glucose limitation, nitrogen starvation, environmental stress, and entry into stationary phase" Verified chr6:174257-176383 174257-176383 99.0% 283.42 703.56 920.05 1302.69 948.06 1059.14 493.49 1111.37 1003.60 1.82 4.51 4.16 -0.15 0.12 Frag>80[1905,1906,1907]
YFR016C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and bud; interacts with Spa2p; YFL016C is not an essential gene Verified chr6:177034-180735 177034-180735 93.2% 238.87 248.44 218.29 226.40 259.45 382.65 243.65 222.35 321.05 0.90 0.90 1.33 0.53 1.28 Matched[1908]
YFR017C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; YFR017C is not an essential gene Uncharacterized chr6:182262-182849 182262-182849 98.2% 55.40 174.87 186.99 212.96 1063.05 630.21 115.13 199.97 846.63 0.43 0.81 3.51 2.08 1.84 Matched[1909]
YFR018C Putative protein of unknown function Uncharacterized chr6:183119-184210 183119-184210 98.4% 213.95 240.00 232.56 185.12 114.42 58.60 226.98 208.84 86.51 0.84 0.85 0.36 -1.27 -0.95 Matched[1910]
YFR019W FAB1 "1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylinositol (3,5)P2, which is involved in vacuolar sorting and homeostasis" Verified chr6:184490-191326 184490-191326 98.4% 61.36 67.60 52.74 61.21 48.43 73.39 64.48 56.98 60.91 0.24 0.23 0.25 0.10 0.34 Frag>80[1911,1912]
YFR020W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr6:192726-193424 192726-193424 98.7% 137.63 198.48 123.14 108.66 131.84 82.58 168.06 115.90 107.21 0.62 0.47 0.44 -0.11 0.02 Frag<80[1914]
YFR021W ATG18 "Phosphatidylinositol 3,5-bisphosphate-binding protein of the vacuolar membrane, predicted to fold as a seven-bladed beta-propeller; required for recycling of Atg9p through the pre-autophagosomal structure" Verified chr6:194800-196302 194800-196302 98.6% 97.14 112.65 72.85 76.90 118.73 136.26 104.90 74.88 127.49 0.39 0.30 0.53 0.77 1.29 Matched[1915]
YFR022W ROG3 "Protein that binds to Rsp5p, which is a hect-type ubiquitin ligase, via its 2 PY motifs; has similarity to Rod1p; mutation suppresses the temperature sensitivity of an mck1 rim11 double mutant" Verified chr6:196821-199022 196821-199022 98.9% 69.33 102.85 62.45 56.94 68.88 69.33 86.09 59.69 69.11 0.32 0.24 0.29 0.21 1.11 Matched[1916]
YFR023W PES4 "Poly(A) binding protein, suppressor of DNA polymerase epsilon mutation, similar to Mip6p" Verified chr6:199862-201697 199862-201697 98.9% 2.75 1.65 2.75 0.55 7.16 2.75 2.20 1.65 4.96 0.01 0.01 0.02 1.58 0.80 Frag<80[1917]
YFR024C-A LSB3 "Protein containing a C-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization" Verified chr6:201948-203421 201948-203256,203375-203421 98.9% 492.09 471.22 452.58 465.25 618.10 524.90 481.66 458.91 571.50 1.78 1.86 2.37 0.32 0.80 Matched[1918]
YFR025C HIS2 "Histidinolphosphatase, catalyzes the eighth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control" Verified chr6:203731-204738 203731-204738 99.0% 183.44 268.65 197.48 174.42 291.70 204.49 226.05 185.95 248.10 0.83 0.75 1.03 0.42 0.34 Matched[1919]
YFR026C Putative protein of unknown function Uncharacterized chr6:205736-206245 205736-206245 99.0% 39.61 47.53 39.61 29.71 57.44 37.63 43.57 34.66 47.53 0.16 0.14 0.20 0.46 0.59 Covered[1921]
YFR027W ECO1 "Acetyltransferase required for the establishment of sister chromatid cohesion during DNA replication, but not for its maintenance during G2 and M phases; also required for postreplicative double-strand break repair; interacts with Chl1p" Verified chr6:207440-208285 207440-208285 98.3% 50.52 32.47 38.49 43.30 60.14 31.27 41.50 40.89 45.71 0.15 0.17 0.19 0.16 0.53 Matched[1922]
YFR028C CDC14 "Protein phosphatase required for mitotic exit; located in the nucleolus until liberated by the FEAR and Mitotic Exit Network in anaphase, enabling it to act on key substrates to effect a decrease in CDK/B-cyclin activity and mitotic exit" Verified chr6:208401-210056 208401-210056 98.9% 215.58 202.14 225.35 192.37 148.40 103.82 208.86 208.86 126.11 0.77 0.85 0.52 -0.73 -0.22 Matched[1923]
YFR029W PTR3 "Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes" Verified chr6:210925-212961 210925-212961 98.8% 52.19 68.59 52.19 46.72 71.57 66.10 60.39 49.45 68.84 0.22 0.20 0.29 0.48 1.00 Covered/w/another[1924]
YFR030W MET10 "Subunit alpha of assimilatory sulfite reductase, which is responsible for the conversion of sulfite into sulfide" Verified chr6:213300-216407 213300-216407 99.0% 55.24 90.67 50.37 42.25 45.82 54.92 72.96 46.31 50.37 0.27 0.19 0.21 0.12 0.68 Covered/w/another[1924]
YFR031C SMC2 "Component of the condensin complex, essential SMC chromosomal ATPase family member that forms a complex with Smc4p to form the active ATPase; Smc2p/Smc4p complex binds DNA, possibly in the cleft formed by the coiled-coil of the folded dimer" Verified chr6:216582-220094 216582-220094 99.4% 112.51 105.64 80.73 69.28 46.67 49.24 109.08 75.01 47.95 0.40 0.30 0.20 -0.65 -0.44 Covered/w/another[1924]
YFR031C-A RPL2A "Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and has similarity to E. coli L2 and rat L8 ribosomal proteins" Verified chr6:220495-221406 220495-221255,221403-221406 44.3% 7427.94 5514.19 6357.54 5410.98 1150.02 905.27 6471.06 5884.26 1027.64 23.89 23.89 4.26 -2.52 -3.15 Frag>80[1925,1926]
YFR032C Putative protein of unknown function; transcribed during sporulation; YFR032C is not an essential gene Uncharacterized chr6:222078-222947 222078-222947 98.5% 11.67 8.17 2.33 2.33 1.17 17.50 9.92 2.33 9.33 0.04 0.01 0.04 2.00 0.28
YFR032C-A RPL29 "Protein component of the large (60S) ribosomal subunit, has similarity to rat L29 ribosomal protein; not essential for translation, but required for proper joining of the large and small ribosomal subunits and for normal translation rate" Verified chr6:223246-223760 223246-223428,223759-223760 98.4% 13227.18 10712.42 11794.10 11008.92 4639.67 3514.07 11969.80 11401.51 4076.87 44.19 46.28 16.89 -1.48 -3.27 Matched[1927]
YFR032C-B "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr6:223698-223961 223698-223961 98.9% 72.79 45.97 38.31 65.12 19.15 45.97 59.38 51.72 32.56 0.22 0.21 0.13 -0.67 NaN Matched[1927]
YFR033C QCR6 "Subunit 6 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; highly acidic protein; required for maturation of cytochrome c1" Verified chr6:224314-224757 224314-224757 98.0% 992.72 1052.47 1116.81 1452.32 2123.32 1459.21 1022.60 1284.57 1791.27 3.77 5.21 7.42 0.48 0.04 Matched[1928]
YFR034C PHO4 Basic helix-loop-helix (bHLH) transcription factor of the myc-family; binds cooperatively with Pho2p to the PHO5 promoter; function is regulated by phosphorylation at multiple sites and by phosphate availability Verified chr6:225008-225946 225008-225946 98.5% 176.31 205.52 159.00 106.00 53.00 62.74 190.91 132.50 57.87 0.70 0.54 0.24 -1.20 -0.66 Matched[1929]
YFR034W-A "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps YFR035C; identified by gene-trapping, microarray expression analysis, and genome-wide homology searching" Dubious chr6:226010-226297 226010-226297 98.2% 127.25 109.57 91.90 102.50 42.42 31.81 118.41 97.20 37.11 0.44 0.39 0.15 -1.39 NaN Covered/w/another[1929]
YFR035C "Putative protein of unknown function, deletion mutant exhibits synthetic phenotype with alpha-synuclein" Uncharacterized chr6:226109-226453 226109-226453 98.4% 259.33 232.81 271.12 253.44 97.25 94.30 246.07 262.28 95.78 0.91 1.06 0.40 -1.45 -0.64 Frag<80[1930]
YFR036W CDC26 "Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" Verified chr6:226950-227324 226950-227324 98.2% 67.87 57.01 57.01 29.86 119.44 84.15 62.44 43.43 101.80 0.23 0.18 0.42 1.23 0.66 Matched[1931]
YFR036W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene RSC8" Dubious chr6:227438-228088 227438-228088 99.3% 958.82 813.45 813.45 731.49 647.98 518.07 886.14 772.47 583.03 3.27 3.14 2.42 -0.41 NaN Matched[1932]
YFR037C RSC8 "Component of the RSC chromatin remodeling complex; essential for viability and mitotic growth; homolog of SWI/SNF subunit Swi3p, but unlike Swi3p, does not activate transcription of reporters" Verified chr6:227500-229173 227500-229173 99.0% 666.62 593.62 579.75 511.58 411.43 373.43 630.12 545.66 392.43 2.33 2.21 1.63 -0.48 0.02 Frag>80[1931,1932,1933]
YFR038W Putative ATPase containing the DEAD/H helicase-related sequence motif; null mutant displays increased levels of spontaneous Rad52 foci Uncharacterized chr6:229367-231928 229367-231928 98.8% 130.04 113.43 113.04 98.02 66.01 50.20 121.74 105.53 58.10 0.45 0.43 0.24 -0.86 -0.54 Covered/w/another[1934]
YFR039C Putative protein of unknown function; YFR039C is not an essential gene Uncharacterized chr6:231999-233531 231999-233531 99.2% 144.05 147.99 128.92 143.39 100.64 92.09 146.02 136.15 96.36 0.54 0.55 0.40 -0.50 -0.01 Covered/w/another[1934]
YFR040W SAP155 "Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap185p, and Sap190p" Verified chr6:234229-237237 234229-237237 98.8% 209.89 187.69 182.98 174.91 137.57 141.61 198.79 178.95 139.59 0.73 0.73 0.58 -0.36 -0.07 Covered/w/another[1935]
YFR041C ERJ5 Type I membrane protein with a J domain is required to preserve the folding capacity of the endoplasmic reticulum; loss of the non-essential ERJ5 gene leads to a constitutively induced unfolded protein response Verified chr6:237355-238242 237355-238242 99.3% 318.77 252.98 269.99 247.31 267.73 172.43 285.88 258.65 220.08 1.06 1.05 0.91 -0.23 -0.43 Covered/w/another[1935]
YFR042W Protein of unknown function required for cell viability; localizes to the endoplasmic reticulum membrane Uncharacterized chr6:238445-239047 238445-239047 99.2% 120.36 132.06 175.52 163.82 407.88 213.97 126.21 169.67 310.93 0.47 0.69 1.29 0.87 0.31 Matched[1936]
YFR043C Hypothetical protein; null mutant displays increased levels of spontaneous Rad52 foci Uncharacterized chr6:239101-239814 239101-239814 99.2% 80.45 73.39 80.45 52.22 110.09 49.40 76.92 66.33 79.74 0.28 0.27 0.33 0.27 0.27 Matched[1937]
YFR044C DUG1 Probable di- and tri-peptidase; forms a complex with Dug2p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p) Verified chr6:239979-241424 239979-241424 98.8% 698.84 981.04 729.65 780.77 895.61 791.97 839.94 755.21 843.79 3.10 3.07 3.50 0.16 0.56 Matched[1938]
YFR045W "Putative mitochondrial transport protein; null mutant is viable, exhibits decreased levels of chitin and normal resistance to calcofluor white" Uncharacterized chr6:241985-242986 241985-241996,242069-242986 99.0% 90.13 140.08 130.31 106.42 199.81 111.85 115.11 118.37 155.83 0.42 0.48 0.65 0.40 0.29 Matched[1939]
YFR046C CNN1 "Kinetochore protein of unknown function; associated with the essential kinetochore proteins Nnf1p and Spc24p; phosphorylated by both Clb5-Cdk1 and, to a lesser extent, Clb2-Cdk1." Verified chr6:243061-244146 243061-244146 99.2% 71.47 81.68 66.83 57.55 66.83 38.99 76.58 62.19 52.91 0.28 0.25 0.22 -0.23 0.06 Matched[1940]
YFR047C BNA6 "Quinolinate phosphoribosyl transferase, required for biosynthesis of nicotinic acid from tryptophan via kynurenine pathway" Verified chr6:244266-245153 244266-245153 99.1% 647.79 821.67 639.83 601.19 888.72 769.39 734.73 620.51 829.06 2.71 2.52 3.44 0.42 0.72 Matched[1941]
YFR048W RMD8 Cytosolic protein required for sporulation Verified chr6:246133-248121 246133-248121 98.7% 86.04 73.32 88.08 68.73 77.39 60.08 79.68 78.41 68.73 0.29 0.32 0.28 -0.19 0.39 Matched[1942]
YFR049W YMR31 "Mitochondrial ribosomal protein of the small subunit, has similarity to human mitochondrial ribosomal protein MRP-S36" Verified chr6:248510-248881 248510-248881 98.4% 322.44 472.73 483.66 508.25 1016.51 743.25 397.59 495.96 879.88 1.47 2.01 3.65 0.83 0.47 Matched[1943]
YFR050C PRE4 20S proteasome beta-type subunit Verified chr6:249053-249853 249053-249853 99.0% 724.75 644.08 780.21 646.60 1221.36 772.65 684.42 713.41 997.01 2.53 2.90 4.13 0.48 0.47 Matched[1944]
YFR051C RET2 "Delta subunit of the coatomer complex (COPI), which coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ER" Verified chr6:250150-251790 250150-251790 98.6% 622.65 589.26 622.65 573.80 531.13 422.93 605.95 598.22 477.03 2.24 2.43 1.98 -0.33 0.32 Frag>80[1945,1946]
YFR052W RPN12 "Subunit of the 19S regulatory particle of the 26S proteasome lid; synthetically lethal with RPT1, which is an ATPase component of the 19S regulatory particle; physically interacts with Nob1p and Rpn3p" Verified chr6:252492-253316 252492-253316 99.0% 506.86 370.96 495.84 412.59 839.87 531.35 438.91 454.22 685.61 1.62 1.84 2.84 0.59 0.62 Matched[1947]
YFR052C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr6:253416-253721 253416-253721 99.1% 2565.89 6243.23 6338.88 6701.66 15576.75 7641.61 4404.56 6520.27 11609.18 16.26 26.47 48.10 0.83 NaN Matched[1948]
YFR053C HXK1 "Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of glucose during glucose metabolism; expression is highest during growth on non-glucose carbon sources; glucose-induced repression involves the hexokinase Hxk2p" Verified chr6:253579-255036 253579-255036 98.5% 2007.02 5135.55 5470.40 6018.97 10750.05 7770.50 3571.28 5744.68 9260.28 13.18 23.32 38.37 0.69 -0.07 Frag>80[1948,1949,1950]
YFR054C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr6:258842-259420 258842-259420 98.4% 8.77 5.26 5.26 3.51 21.05 5.26 7.02 4.39 13.16 0.03 0.02 0.05 1.58 1.56
YFR055W "Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52 foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner" Uncharacterized chr6:264191-265213 264191-265213 98.5% 300.79 193.58 212.44 146.92 57.58 48.64 247.19 179.68 53.11 0.91 0.73 0.22 -1.76 -1.77 Matched[1951]
YFR056C Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W Dubious chr6:263944-264312 263944-264312 99.1% 92.94 65.60 82.00 60.14 27.33 24.60 79.27 71.07 25.97 0.29 0.29 0.11 -1.45 -0.31 Covered/w/another[1951]
YFR057W Putative protein of unknown function Uncharacterized chr6:269048-269503 269048-269503 99.3% 0.00 0.00 0.00 2.21 0.00 2.21 0.00 1.10 1.10 0.00 0.00 0.00 0.00 0.03
YGL263W COS12 "Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" Verified chr7:2790-3932 2790-3932 99.1% 23.83 9.71 13.24 12.36 7.94 4.41 16.77 12.80 6.18 0.06 0.05 0.03 -1.05 -1.97
YGL262W Putative protein of unknown function; null mutant displays elevated sensitivity to expression of a mutant huntingtin fragment or of alpha-synuclein; YGL262W is not an essential gene Uncharacterized chr7:5312-5839 5312-5839 98.6% 3.84 0.00 1.92 0.00 7.68 1.92 1.92 0.96 4.80 0.01 0.00 0.02 2.32 0.14
YGL261C Putative protein of unknown function; mRNA expression appears to be regulated by SUT1 and UPC2 Uncharacterized chr7:6290-6652 6290-6652 9.4% 0.00 0.00 29.27 0.00 29.27 0.00 0.00 14.63 14.63 0.00 0.06 0.06 0.00 0.78
YGL260W Putative protein of unknown function; transcription is significantly increased in a NAP1 deletion background; deletion mutant has increased accumulation of nickel and selenium Uncharacterized chr7:6860-7090 6860-7090 2.5% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.13
YGL259W YPS5 Protein with similarity to GPI-anchored aspartic proteases such as Yap1p and Yap3p Uncharacterized chr7:8470-8967 8470-8967 38.0% 21.14 26.42 26.42 21.14 89.83 73.98 23.78 23.78 81.90 0.09 0.10 0.34 1.78 2.90 Overlap[1954]
YGL258W-A Putative protein of unknown function Uncharacterized chr7:9162-9395 9162-9395 98.9% 12.96 30.23 12.96 30.23 146.84 90.70 21.59 21.59 118.77 0.08 0.09 0.49 2.46 2.81 Covered[1954]
YGL258W VEL1 Protein of unknown function; highly induced in zinc-depleted conditions and has increased expression in NAP1 deletion mutants Verified chr7:11110-11730 11110-11730 65.4% 9.85 29.54 14.77 9.85 12.31 4.92 19.70 12.31 8.62 0.07 0.05 0.04 -0.51 -0.52
YGL257C MNT2 Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans Verified chr7:12481-14157 12481-14157 99.3% 193.37 163.34 165.75 162.14 75.07 56.45 178.36 163.94 65.76 0.66 0.67 0.27 -1.32 -0.96 Matched[1955]
YGL256W ADH4 "Alcohol dehydrogenase isoenzyme type IV, dimeric enzyme demonstrated to be zinc-dependent despite sequence similarity to iron-activated alcohol dehydrogenases; transcription is induced in response to zinc deficiency" Verified chr7:14910-16307 14910-16307 99.0% 210.25 221.09 180.63 145.23 105.49 88.15 215.67 162.93 96.82 0.80 0.66 0.40 -0.75 -0.37 Matched[1956]
YGL255W ZRT1 "High-affinity zinc transporter of the plasma membrane, responsible for the majority of zinc uptake; transcription is induced under low-zinc conditions by the Zap1p transcription factor" Verified chr7:20978-22108 20978-22108 98.8% 186.95 161.90 130.60 124.33 50.99 44.72 174.43 127.46 47.86 0.64 0.52 0.20 -1.41 -1.07 Covered[1958]
YGL254W FZF1 "Transcription factor involved in sulfite metabolism, sole identified regulatory target is SSU1, overexpression suppresses sulfite-sensitivity of many unrelated mutants due to hyperactivation of SSU1, contains five zinc fingers" Verified chr7:22304-23203 22304-23203 98.8% 86.59 92.21 55.10 67.47 44.98 29.24 89.40 61.29 37.11 0.33 0.25 0.15 -0.72 -0.37 Matched[1959]
YGL253W HXK2 Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosol; predominant hexokinase during growth on glucose; functions in the nucleus to repress expression of HXK1 and GLK1 and to induce expression of its own gene Verified chr7:23935-25395 23935-25395 98.0% 4445.74 2896.54 5142.81 5132.33 1480.75 1111.26 3671.14 5137.57 1296.00 13.55 20.85 5.37 -1.99 -2.61 Matched[1960]
YGL252C RTG2 "Sensor of mitochondrial dysfunction; regulates the subcellular location of Rtg1p and Rtg3p, transcriptional activators of the retrograde (RTG) and TOR pathways; Rtg2p is inhibited by the phosphorylated form of Mks1p" Verified chr7:25718-27484 25718-27484 99.2% 252.13 247.56 273.23 248.70 281.79 244.14 249.85 260.97 262.97 0.92 1.06 1.09 0.01 0.47 Frag>80[1961,1962]
YGL251C HFM1 Meiosis specific DNA helicase involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control; catalyzes the unwinding of Holliday junctions; has ssDNA and dsDNA stimulated ATPase activity Verified chr7:27921-31636 27921-31426,31579-31636 99.3% 34.21 39.58 30.53 24.88 36.75 32.51 36.89 27.70 34.63 0.14 0.11 0.14 0.32 0.29 Frag<80[1963]
YGL250W Putative protein of unknown function; deletion mutant results in reduced PIS1 expression and has growth defects on non-fermentable carbon sources and on minimal media; GFP-fusion protein localizes to both the cytoplasm and the nucleus Uncharacterized chr7:31910-32635 31910-32635 98.7% 71.14 112.99 118.57 94.86 206.45 156.23 92.07 106.71 181.34 0.34 0.43 0.75 0.76 0.48 Frag>80[1964,1965]
YGL249W ZIP2 Meiosis-specific protein involved in normal synaptonemal complex formation and pairing between homologous chromosomes during meiosis Verified chr7:33098-35212 33098-35212 98.8% 19.13 24.87 11.00 11.00 30.61 18.66 22.00 11.00 24.63 0.08 0.04 0.10 1.16 0.81 Frag<80[1965,1966]
YGL248W PDE1 "Low-affinity cyclic AMP phosphodiesterase, controls glucose and intracellular acidification-induced cAMP signaling, target of the cAMP-protein kinase A (PKA) pathway; glucose induces transcription and inhibits translation" Verified chr7:35653-36762 35653-36762 98.6% 166.25 274.04 159.85 156.20 379.08 363.55 220.14 158.03 371.32 0.81 0.64 1.54 1.23 1.36 Matched[1967]
YGL247W BRR6 "Essential nuclear envelope integral membrane protein required for nuclear transport; depletion alters nucleoporin distribution and nuclear envelope morphology, suggesting a role in the spatial organization of nuclear pores" Verified chr7:36933-37526 36933-37526 98.8% 90.29 97.10 83.48 40.89 114.14 34.07 93.70 62.18 74.11 0.35 0.25 0.31 0.25 -0.52 Covered/w/another[1968]
YGL246C RAI1 "Nuclear protein that binds to and stabilizes the exoribonuclease Rat1p, required for pre-rRNA processing" Verified chr7:37617-38780 37617-38780 99.3% 181.61 147.02 151.34 129.72 113.29 70.91 164.31 140.53 92.10 0.61 0.57 0.38 -0.61 -0.44 Covered/w/another[1968]
YGL245W GUS1 "Glutamyl-tRNA synthetase (GluRS), forms a complex with methionyl-tRNA synthetase (Mes1p) and Arc1p; complex formation increases the catalytic efficiency of both tRNA synthetases and ensures their correct localization to the cytoplasm" Verified chr7:39023-41149 39023-41149 98.7% 1531.94 1483.84 1447.17 1570.03 831.92 985.26 1507.89 1508.60 908.59 5.57 6.12 3.76 -0.73 -0.13 Matched[1969]
YGL244W RTF1 Subunit of the RNA polymerase II-associated Paf1 complex; directly or indirectly regulates DNA-binding properties of Spt15p and relative activities of different TATA elements; involved in telomere maintenance Verified chr7:41498-43174 41498-43174 98.2% 364.48 326.82 351.73 347.47 301.91 262.43 345.65 349.60 282.17 1.28 1.42 1.17 -0.31 0.08 Matched[1970]
YGL243W TAD1 "tRNA-specific adenosine deaminase, deaminates adenosine-37 to inosine in tRNA-Ala" Verified chr7:43307-44509 43307-44509 98.7% 106.09 104.40 73.25 78.30 78.30 40.41 105.24 75.78 59.36 0.39 0.31 0.25 -0.35 -0.71 Matched[1971]
YGL242C Putative protein of unknown function; deletion mutant is viable Uncharacterized chr7:44652-45197 44652-45197 99.4% 379.46 440.25 357.36 337.09 757.08 477.09 409.85 347.23 617.08 1.51 1.41 2.56 0.83 0.47 Frag>80[1972,1973]
YGL241W KAP114 "Karyopherin, responsible for nuclear import of Spt15p, histones H2A and H2B, and Nap1p; amino terminus shows similarity to those of other importins, particularly Cse1p; localization is primarily nuclear" Verified chr7:45445-48459 45445-48459 98.9% 94.54 85.49 72.08 63.70 62.69 45.26 90.01 67.89 53.97 0.33 0.28 0.22 -0.33 -0.30 Matched[1974]
YGL240W DOC1 "Processivity factor required for the ubiquitination activity of the anaphase promoting complex (APC), mediates the activity of the APC by contributing to substrate recognition; involved in cyclin proteolysis" Verified chr7:48613-49365 48613-49365 98.6% 22.89 28.28 18.85 24.24 20.20 21.55 25.58 21.55 20.87 0.09 0.09 0.09 -0.05 0.80 Covered/w/another[1975]
YGL238W CSE1 "Nuclear envelope protein that mediates the nuclear export of importin alpha (Srp1p), homolog of metazoan CAS protein, required for accurate chromosome segregation" Verified chr7:49552-52434 49552-52434 99.2% 355.37 312.00 296.61 282.62 282.27 241.70 333.69 289.62 261.98 1.23 1.18 1.09 -0.14 0.33 Covered/w/another[1975]
YGL239C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene CSE1" Dubious chr7:49431-49745 49431-49745 98.5% 128.98 122.53 106.41 125.76 132.20 116.08 125.76 116.08 124.14 0.46 0.47 0.51 0.10 0.06 Covered/w/another[1975]
YGL237C HAP2 "Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; contains sequences sufficient for both complex assembly and DNA binding" Verified chr7:52731-53528 52731-53528 97.1% 79.98 112.23 73.53 70.95 198.67 179.32 96.11 72.24 188.99 0.35 0.29 0.78 1.39 1.00 Covered/w/another[1975]
YGL235W Putative protein of unknown function; potential Cdc28p substrate Uncharacterized chr7:55279-55815 55279-55815 98.5% 54.82 26.46 43.47 26.46 3.78 9.45 40.64 34.97 6.62 0.15 0.14 0.03 -2.40 0.03 Covered/w/another[1976]
YGL236C MTO1 "Mitochondrial protein, forms a heterodimer complex with Mss1p that performs the 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs; required for respiration in paromomycin-resistant 15S rRNA mutants" Verified chr7:53787-55796 53787-55796 98.8% 83.60 59.43 73.03 53.39 14.10 22.66 71.52 63.21 18.38 0.26 0.26 0.08 -1.78 -1.38 Matched[1976]
YGL234W "ADE5,7" "Bifunctional enzyme of the 'de novo' purine nucleotide biosynthetic pathway, contains aminoimidazole ribotide synthetase and glycinamide ribotide synthetase activities" Verified chr7:56482-58890 56482-58890 98.7% 1867.34 1141.60 1795.02 1304.32 230.42 125.30 1504.47 1549.67 177.86 5.55 6.29 0.74 -3.12 -2.59 Matched[1977]
YGL233W SEC15 "Essential 113kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which mediates polarized targeting of vesicles to active sites of exocytosis; Sec15p associates with Sec4p and vesicles" Verified chr7:59122-61854 59122-61854 99.0% 132.73 159.34 131.62 131.99 180.42 147.88 146.03 131.80 164.15 0.54 0.54 0.68 0.32 0.62 Matched[1978]
YGL232W TAN1 "Putative tRNA acetyltransferase, RNA-binding protein required for the formation of the modified nucleoside N(4)-acetylcytidine in serine and leucine tRNAs but not required for the same modification in 18S rRNA" Verified chr7:62075-63002 62075-62131,62190-63002 98.7% 343.66 344.82 271.43 287.74 316.86 172.41 344.24 279.58 244.64 1.27 1.13 1.01 -0.19 -0.19 Matched[1979]
YGL231C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum Uncharacterized chr7:63048-63620 63048-63620 99.0% 608.02 534.00 567.48 477.60 484.65 289.03 571.01 522.54 386.84 2.11 2.12 1.60 -0.43 -0.47 Covered/w/another[1979]
YGL230C Putative protein of unknown function; non-essential gene Uncharacterized chr7:63772-64215 63772-64215 99.2% 9.08 20.44 18.16 9.08 20.44 20.44 14.76 13.62 20.44 0.05 0.06 0.08 0.58 0.39 Matched[1980]
YGL229C SAP4 "Protein required for function of the Sit4p protein phosphatase, member of a family of similar proteins that form complexes with Sit4p, including Sap155p, Sap185p, and Sap190p" Verified chr7:64503-66959 64503-66959 99.2% 100.55 135.44 106.30 96.04 151.86 123.95 118.00 101.17 137.90 0.44 0.41 0.57 0.45 0.66 Matched[1981]
YGL228W SHE10 Putative glycosylphosphatidylinositol (GPI)-anchored protein of unknown function; overexpression causes growth arrest Verified chr7:67598-69331 67598-69331 98.5% 347.68 353.54 353.54 361.14 356.46 273.93 350.61 357.34 315.20 1.29 1.45 1.31 -0.18 0.23 Matched[1982]
YGL227W VID30 "Protein involved in proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBPase); shifts the balance of nitrogen metabolism toward the production of glutamate; localized to the nucleus and the cytoplasm" Verified chr7:69671-72547 69671-72547 97.9% 84.81 94.40 94.75 102.91 198.37 196.60 89.61 98.83 197.49 0.33 0.40 0.82 1.00 1.03 Matched[1983]
YGL226C-A OST5 "Zeta subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins" Verified chr7:72748-73157 72748-72987,73137-73157 98.5% 739.30 669.26 677.04 723.74 525.29 451.36 704.28 700.39 488.33 2.60 2.84 2.02 -0.52 -0.14 Covered/w/another[1983]
YGL226W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion Uncharacterized chr7:73339-73710 73339-73710 98.0% 145.32 191.93 170.00 156.29 233.06 139.84 168.63 163.14 186.45 0.62 0.66 0.77 0.19 0.03 Matched[1984]
YGL225W VRG4 Golgi GDP-mannose transporter; regulates Golgi function and glycosylation in Golgi Verified chr7:76893-77906 76893-77906 99.2% 1474.89 1673.79 1303.83 1251.12 429.64 318.25 1574.34 1277.47 373.94 5.81 5.19 1.55 -1.77 -1.74 Matched[1987]
YGL224C SDT1 "Pyrimidine nucleotidase; overexpression suppresses the 6-AU sensitivity of transcription elongation factor S-II, as well as resistance to other pyrimidine derivatives" Verified chr7:78014-78856 78014-78856 99.2% 199.67 307.28 191.30 127.93 178.15 80.11 253.47 159.62 129.13 0.94 0.65 0.54 -0.31 -0.83 Covered/w/another[1988]
YGL223C COG1 "Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" Verified chr7:79111-80364 79111-80364 99.0% 156.23 172.33 115.96 120.79 132.07 69.25 164.28 118.38 100.66 0.61 0.48 0.42 -0.23 -0.15 Covered/w/another[1988]
YGL222C EDC1 "RNA-binding protein, activates mRNA decapping directly by binding to the mRNA substrate and enhancing the activity of the decapping proteins Dcp1p and Dcp2p" Verified chr7:80658-81185 80658-81185 98.7% 218.72 289.71 203.37 234.07 320.41 335.76 254.22 218.72 328.08 0.94 0.89 1.36 0.58 1.33 Frag<80[1989]
YGL221C NIF3 "Protein of unknown function, similar to Listeria monocytogenes major sigma factor (rpoD gene product); the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr7:81425-82291 81425-82291 98.9% 338.29 331.29 331.29 291.63 400.12 317.29 334.79 311.46 358.71 1.24 1.26 1.49 0.20 0.32 Matched[1990]
YGL220W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus Uncharacterized chr7:82373-82735 82373-82735 98.3% 417.37 442.58 434.17 350.14 571.43 355.74 429.97 392.16 463.59 1.59 1.59 1.92 0.24 -0.43 Matched[1991]
YGL218W "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 93% of ORF overlaps the verified gene MDM34; deletion in cyr1 mutant results in loss of stress resistance" Dubious chr7:83649-84299 83649-84299 99.1% 136.43 187.60 164.34 145.74 189.15 213.95 162.02 155.04 201.55 0.60 0.63 0.84 0.38 0.33 Matched[1992]
YGL219C MDM34 "Mitochondrial outer membrane protein, required for normal mitochondrial morphology and inheritance; localizes to dots on the mitochondrial surface near mtDNA nucleoids; interacts genetically with MDM31 and MDM32" Verified chr7:82877-84256 82877-84256 98.9% 177.97 243.89 179.44 202.14 281.97 242.42 210.93 190.79 262.20 0.78 0.77 1.09 0.46 0.54 Matched[1992]
YGL216W KIP3 Kinesin-related motor protein involved in mitotic spindle positioning Verified chr7:84884-87301 84884-87301 98.6% 86.80 105.25 78.00 75.48 59.96 74.64 96.03 76.74 67.30 0.35 0.31 0.28 -0.19 0.36 Matched[1993]
YGL217C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF KIP3/YGL216W" Dubious chr7:84838-85179 84838-85179 98.4% 47.55 92.12 56.46 56.46 23.77 59.44 69.84 56.46 41.60 0.26 0.23 0.17 -0.44 -0.02 Covered/w/another[1993]
YGL215W CLG1 Cyclin-like protein that interacts with Pho85p; has sequence similarity to G1 cyclins PCL1 and PCL2 Verified chr7:87980-89338 87980-89338 99.2% 1103.24 1303.43 1000.93 1126.23 954.96 1168.49 1203.34 1063.58 1061.72 4.44 4.32 4.40 -0.00 0.58 Matched[1994]
YGL214W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; deletion mutation phenotype is likely due to the overlapping verified ORF SKI8/YGL213C" Dubious chr7:90011-90499 90011-90499 99.2% 265.91 259.73 272.09 239.11 197.89 189.64 262.82 255.60 193.76 0.97 1.04 0.80 -0.40 -0.36 Covered/w/another[1995]
YGL213C SKI8 Protein involved in exosome mediated 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs as well as double-strand break formation during meiotic recombination; required for repressing propagation of dsRNA viruses Verified chr7:90058-91251 90058-91251 99.0% 232.62 197.09 234.31 201.32 186.94 146.34 214.85 217.81 166.64 0.79 0.88 0.69 -0.39 -0.24 Matched[1995]
YGL212W VAM7 Component of the vacuole SNARE complex involved in vacuolar morphogenesis; SNAP-25 homolog; functions with a syntaxin homolog Vam3p in vacuolar protein trafficking Verified chr7:91436-92386 91436-92386 98.0% 71.89 68.68 39.70 62.24 53.65 55.80 70.29 50.97 54.73 0.26 0.21 0.23 0.10 0.74 Covered/w/another[1996]
YGL211W NCS6 "Protein required for thiolation of the uridine at the wobble position of Gln, Lys, and Glu tRNAs; has a role in urmylation and in invasive and pseudohyphal growth; inhibits replication of Brome mosaic virus in S. cerevisiae" Verified chr7:92516-93595 92516-93595 98.3% 196.77 161.93 167.58 132.75 114.86 104.50 179.35 150.16 109.68 0.66 0.61 0.45 -0.45 0.14 Covered/w/another[1996]
YGL210W YPT32 "GTPase of the Ypt/Rab family, very similar to Ypt31p; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi" Verified chr7:93797-94465 93797-94465 98.3% 250.79 246.23 238.63 153.51 117.04 56.24 248.51 196.07 86.64 0.92 0.80 0.36 -1.18 -0.40 Covered/w/another[1996]
YGL209W MIG2 "Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter" Verified chr7:95862-97010 95862-97010 98.7% 137.59 142.88 87.32 75.85 69.68 41.45 140.24 81.58 55.57 0.52 0.33 0.23 -0.55 -2.13 Covered/w/another[1997]
YGL208W SIP2 One of three beta subunits of the Snf1 serine/threonine protein kinase complex involved in the response to glucose starvation; null mutants exhibit accelerated aging; N-myristoylprotein localized to the cytoplasm and the plasma membrane Verified chr7:97342-98589 97342-98589 98.6% 69.10 109.74 95.92 80.48 220.30 154.45 89.42 88.20 187.37 0.33 0.36 0.78 1.09 1.48 Covered/w/another[1997]
YGL207W SPT16 "Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), facilitates RNA Polymerase II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure" Verified chr7:98973-102080 98973-102080 98.7% 438.29 327.17 396.58 367.90 284.81 273.08 382.73 382.24 278.94 1.41 1.55 1.16 -0.45 -0.10 Covered/w/another[1997]
YGL206C CHC1 "Clathrin heavy chain, subunit of the major coat protein involved in intracellular protein transport and endocytosis; two heavy chains form the clathrin triskelion structural component; the light chain (CLC1) is thought to regulate function" Verified chr7:102547-107508 102547-107508 99.1% 369.83 348.47 345.02 364.95 332.81 457.31 359.15 354.98 395.06 1.33 1.44 1.64 0.15 0.78 Frag>80[1998,1999]
YGL205W POX1 "Fatty-acyl coenzyme A oxidase, involved in the fatty acid beta-oxidation pathway; localized to the peroxisomal matrix" Verified chr7:108162-110408 108162-110408 98.8% 14.86 16.66 12.61 9.46 25.22 17.56 15.76 11.03 21.39 0.06 0.04 0.09 0.96 1.14
YGL204C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr7:111704-112009 111704-112009 98.9% 89.23 66.10 62.79 42.96 112.37 79.32 77.66 52.88 95.84 0.29 0.21 0.40 0.86 0.59 Matched[2000]
YGL203C KEX1 Protease involved in the processing of killer toxin and alpha factor precursor; cleaves Lys and Arg residues from the C-terminus of peptides and proteins Verified chr7:112479-114668 112479-114668 99.2% 217.17 251.22 232.81 195.54 188.64 183.58 234.19 214.18 186.11 0.86 0.87 0.77 -0.20 0.22 Frag>80[2001,2002]
YGL202W ARO8 "Aromatic aminotransferase I, expression is regulated by general control of amino acid biosynthesis" Verified chr7:116063-117565 116063-117565 98.9% 939.92 1238.65 943.29 900.90 548.34 634.47 1089.29 922.09 591.40 4.02 3.74 2.45 -0.64 0.10 Matched[2004]
YGL201C MCM6 Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex Verified chr7:117858-120911 117858-120911 98.7% 112.49 94.57 102.54 87.27 46.12 44.47 103.53 94.90 45.29 0.38 0.39 0.19 -1.07 -0.35 Matched[2005]
YGL200C EMP24 "Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport" Verified chr7:122699-123310 122699-123310 98.7% 1213.41 1332.60 1269.69 1301.15 1246.52 922.06 1273.00 1285.42 1084.29 4.70 5.22 4.49 -0.25 -0.33 Frag>80[2006,2007]
YGL198W YIP4 "Protein that interacts with Rab GTPases, localized to late Golgi vesicles; computational analysis of large-scale protein-protein interaction data suggests a possible role in vesicle-mediated transport" Verified chr7:123596-124303 123596-124303 98.6% 374.06 396.99 460.05 442.85 606.23 472.95 385.52 451.45 539.59 1.42 1.83 2.24 0.26 0.24 Matched[2008]
YGL199C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YIP4/YGL198W" Dubious chr7:123577-124047 123577-124047 98.4% 353.73 375.30 457.27 381.77 558.64 450.80 364.52 419.52 504.72 1.35 1.70 2.09 0.27 -0.02 Matched[2008]
YGL197W MDS3 "Protein with an N-terminal kelch-like domain, putative negative regulator of early meiotic gene expression; required, with Pmd1p, for growth under alkaline conditions" Verified chr7:124703-129166 124703-129166 98.8% 106.81 124.72 100.46 89.12 101.37 124.50 115.77 94.79 112.93 0.43 0.38 0.47 0.25 0.79 Covered/w/another[2009]
YGL196W DSD1 "D-serine dehydratase (aka D-serine ammonia-lyase); converts D-serine to pyruvate and ammonia; specifc for D-serine, unlike the bacterial enzyme which recognizes both D-serine and L-serine as substrates" Verified chr7:129888-131174 129888-131174 98.8% 155.67 193.41 160.39 147.81 284.61 173.75 174.54 154.10 229.18 0.64 0.63 0.95 0.57 0.57 Covered/w/another[2009]
YGL195W GCN1 "Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn20p; proposed to stimulate Gcn2p activation by an uncharged tRNA" Verified chr7:131531-139549 131531-139549 98.9% 264.19 237.08 229.01 215.39 80.08 113.24 250.63 222.20 96.66 0.93 0.90 0.40 -1.20 -0.37 Frag>80[2010,2011]
YGL194C-A "Putative protein of unknown function, identified based on comparisons of the genome sequences of six Saccharomyces species" Uncharacterized chr7:139725-139967 139725-139967 99.4% 178.08 78.69 144.95 86.97 186.37 128.39 128.39 115.96 157.38 0.47 0.47 0.65 0.44 NaN Covered/w/another[2012]
YGL194C HOS2 "Histone deacetylase required for gene activation via specific deacetylation of lysines in H3 and H4 histone tails; subunit of the Set3 complex, a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity" Verified chr7:140374-141732 140374-141732 99.1% 73.48 77.19 66.05 64.57 77.19 92.03 75.33 65.31 84.61 0.28 0.27 0.35 0.37 0.85 Matched[2012]
YGL193C "Haploid-specific gene repressed by a1-alpha2, turned off in sir3 null strains, absence enhances the sensitivity of rad52-327 cells to campothecin almost 100-fold" Uncharacterized chr7:141922-142233 141922-142233 98.5% 208.21 224.48 240.75 136.64 230.99 104.11 216.35 188.69 167.55 0.80 0.77 0.69 -0.17 0.23 Covered/w/another[2013]
YGL192W IME4 Probable mRNA N6-adenosine methyltransferase that is required for IME1 transcript accumulation and for sporulation; expression is induced in starved MATa/MAT alpha diploid cells Verified chr7:142252-144054 142252-144054 98.7% 146.65 157.88 132.04 121.36 145.52 100.01 152.27 126.70 122.77 0.56 0.51 0.51 -0.05 0.27 Matched[2013]
YGL191W COX13 "Subunit VIa of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; not essential for cytochrome c oxidase activity but may modulate activity in response to ATP" Verified chr7:144814-145203 144814-145203 98.8% 1087.37 1022.49 1136.68 1235.29 2891.00 2000.87 1054.93 1185.99 2445.93 3.89 4.81 10.13 1.04 -0.00 Matched[2015]
YGL190C CDC55 Non-essential regulatory subunit B of protein phosphatase 2A; has multiple roles in mitosis and protein biosynthesis; found in the nucleus of most cells but also at the bud neck (large-budded cells) and at the bud tip (small-budded cells) Verified chr7:145815-147395 145815-147395 99.5% 241.60 221.89 290.56 236.52 362.40 263.22 231.75 263.54 312.81 0.86 1.07 1.30 0.25 0.78 Matched[2017]
YGL189C RPS26A Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Bp and has similarity to rat S26 ribosomal protein Verified chr7:148235-148973 148235-148604,148972-148973 73.1% 12621.90 11091.08 11098.44 8842.69 5181.23 3536.34 11856.49 9970.56 4358.79 43.77 40.47 18.06 -1.19 -2.77 Matched[2018]
YGL188C-A Putative protein of unknown function Uncharacterized chr7:148830-148970 148830-148970 99.9% 49.72 99.44 56.82 42.62 14.21 28.41 74.58 49.72 21.31 0.28 0.20 0.09 -1.22 NaN Matched[2018]
YGL188C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr7:149349-149522 149349-149522 99.3% 277.72 231.44 196.72 312.44 295.08 190.94 254.58 254.58 243.01 0.94 1.03 1.01 -0.07 0.16 Covered/w/another[2019]
YGL187C COX4 "Subunit IV of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; N-terminal 25 residues of precursor are cleaved during mitochondrial import; phosphorylated" Verified chr7:149710-150532 149710-150189,150531-150532 99.1% 663.87 703.66 818.85 1028.27 963.35 592.67 683.77 923.56 778.01 2.52 3.75 3.22 -0.25 -0.58 Matched[2019]
YGL186C TPN1 "Plasma membrane pyridoxine (vitamin B6) transporter; member of the purine-cytosine permease subfamily within the major facilitator superfamily; proton symporter with similarity to Fcy21p, Fcy2p, and Fcy22p" Verified chr7:151043-152782 151043-152782 99.0% 290.30 308.88 239.21 219.47 144.57 92.32 299.59 229.34 118.44 1.11 0.93 0.49 -0.95 -0.61 Matched[2020]
YGL185C Putative protein with sequence similarity to hydroxyacid dehydrogenases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr7:153173-154312 153173-154312 99.2% 50.40 91.95 54.82 53.05 145.89 113.17 71.18 53.93 129.53 0.26 0.22 0.54 1.26 1.29 Matched[2021]
YGL184C STR3 "Cystathionine beta-lyase, converts cystathionine into homocysteine" Verified chr7:154621-156018 154621-156018 98.9% 7.95 18.80 10.12 5.06 14.46 17.35 13.38 7.59 15.91 0.05 0.03 0.07 1.07 1.32 Overlap[2021]
YGL183C MND1 "Protein required for recombination and meiotic nuclear division; forms a complex with Hop2p, which is involved in chromosome pairing and repair of meiotic double-strand breaks" Verified chr7:156549-157291 156549-157205,157289-157291 99.5% 7.61 6.09 3.05 3.05 15.23 3.05 6.85 3.05 9.14 0.03 0.01 0.04 1.58 0.83
YGL182C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF MND1/YGL183C" Dubious chr7:157279-157602 157279-157602 98.5% 3.13 6.27 0.00 3.13 6.27 6.27 4.70 1.57 6.27 0.02 0.01 0.03 2.00 0.88
YGL181W GTS1 "Protein containing a zinc-finger in the N-terminus and a long Gln-rich region in the C-terminus; regulates ultradian rhythm, cell size, cell cycle, lifespan, sporulation, heat tolerance, and multidrug transport" Verified chr7:157912-159102 157912-159102 98.0% 218.55 231.40 240.83 249.40 310.25 216.83 224.98 245.12 263.54 0.83 0.99 1.09 0.10 0.73 Matched[2022]
YGL180W ATG1 "Protein serine/threonine kinase, required for autophagy and for the cytoplasm-to-vacuole targeting (Cvt) pathway" Verified chr7:160071-162764 160071-162764 98.8% 29.31 35.32 22.17 27.43 63.88 67.26 32.32 24.80 65.57 0.12 0.10 0.27 1.40 1.86 Covered[2023]
YGL179C TOS3 "Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome" Verified chr7:163415-165097 163415-165097 99.0% 36.62 49.22 42.02 33.62 91.85 69.63 42.92 37.82 80.74 0.16 0.15 0.33 1.09 1.51 Covered[2024]
YGL178W MPT5 "Member of the Puf family of RNA-binding proteins; binds to mRNAs encoding chromatin modifiers and spindle pole body components; involved in longevity, maintenance of cell wall integrity, and sensitivity to and recovery from pheromone arrest" Verified chr7:167358-170577 167358-167360,168001-170577 99.1% 125.92 109.10 96.98 85.64 91.90 144.30 117.51 91.31 118.10 0.43 0.37 0.49 0.37 1.42 Matched[2025]
YGL177W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr7:167565-167912 167565-167912 98.9% 17.42 14.52 11.62 8.71 23.23 40.66 15.97 10.16 31.95 0.06 0.04 0.13 1.65 1.66 Covered/w/another[2025]
YGL176C Putative protein of unknown function; deletion mutant is viable and has no detectable phenotype Uncharacterized chr7:171421-173085 171421-173085 99.1% 96.99 111.54 78.81 76.38 76.99 69.11 104.27 77.59 73.05 0.38 0.31 0.30 -0.09 0.44 Covered/w/another[2026]
YGL175C SAE2 Protein with a role in accurate meiotic and mitotic double-strand break repair; phosphorylated in response to DNA damage and required for normal resistance to DNA-damaging agents Verified chr7:173291-174328 173291-174328 99.1% 36.93 34.99 34.99 35.96 25.27 27.21 35.96 35.47 26.24 0.13 0.14 0.11 -0.43 0.77 Covered/w/another[2026]
YGL174W BUD13 "Subunit of the RES complex, which is required for nuclear pre-mRNA retention and splicing; involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern" Verified chr7:174551-175351 174551-175351 98.3% 69.88 63.53 90.21 53.36 83.86 63.53 66.71 71.79 73.69 0.25 0.29 0.31 0.04 0.15 Matched[2027]
YGL173C KEM1 "Evolutionarily-conserved 5'-3' exonuclease component of cytoplasmic processing (P) bodies involved in mRNA decay; plays a role in microtubule-mediated processes, filamentous growth, ribosomal RNA maturation, and telomere maintenance" Verified chr7:175533-180119 175533-180119 99.2% 509.47 437.38 467.93 455.40 255.61 347.27 473.42 461.67 301.44 1.75 1.87 1.25 -0.61 0.07 Frag>80[2028,2029,2030]
YGL172W NUP49 "Subunit of the Nsp1p-Nup57p-Nup49p-Nic96p subcomplex of the nuclear pore complex (NPC), required for nuclear export of ribosomes" Verified chr7:180706-182124 180706-182124 98.8% 236.19 207.65 249.03 232.62 254.03 228.34 221.92 240.83 241.18 0.82 0.98 1.00 0.00 0.64 Matched[2031]
YGL171W ROK1 ATP-dependent RNA helicase of the DEAD box family; required for 18S rRNA synthesis Verified chr7:182396-184090 182396-184090 98.5% 173.67 95.22 107.80 85.04 11.98 0.60 134.45 96.42 6.29 0.50 0.39 0.03 -3.94 -4.81 Matched[2032]
YGL170C SPO74 "Component of the meiotic outer plaque of the spindle pole body, involved in modifying the meiotic outer plaque that is required prior to prospore membrane formation" Verified chr7:184159-185400 184159-185400 99.3% 16.22 5.68 5.68 4.06 7.30 5.68 10.95 4.87 6.49 0.04 0.02 0.03 0.42 0.80 Overlap[2032]
YGL169W SUA5 Protein required for respiratory growth; null mutation suppresses the Cyc1p translation defect caused by the presence of an aberrant ATG codon upstream of the correct start Verified chr7:186065-187345 186065-187345 98.8% 148.53 90.07 91.65 77.43 14.22 10.27 119.30 84.54 12.25 0.44 0.34 0.05 -2.79 -3.46 Matched[2033]
YGL168W HUR1 Protein required for hydroxyurea resistance; has possible roles in DNA replication and maintenance of proper telomere length Verified chr7:187470-187802 187470-187802 98.9% 595.22 586.11 613.44 488.93 646.84 318.87 590.66 551.18 482.85 2.18 2.24 2.00 -0.19 -0.16 Covered/w/another[2034]
YGL167C PMR1 High affinity Ca2+/Mn2+ P-type ATPase required for Ca2+ and Mn2+ transport into Golgi; involved in Ca2+ dependent protein sorting and processing; mutations in human homolog ATP2C1 cause acantholytic skin condition Hailey-Hailey disease Verified chr7:187622-190474 187622-190474 99.1% 336.49 319.86 327.65 294.03 226.10 206.64 328.18 310.84 216.37 1.21 1.26 0.90 -0.52 0.03 Matched[2034]
YGL166W CUP2 Copper-binding transcription factor; activates transcription of the metallothionein genes CUP1-1 and CUP1-2 in response to elevated copper concentrations Verified chr7:191135-191812 191135-191812 98.3% 73.50 83.99 78.00 58.50 197.99 110.99 78.75 68.25 154.49 0.29 0.28 0.64 1.18 1.12 Covered/w/another[2035]
YGL165C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF CUP2/YGL166W" Dubious chr7:191404-191982 191404-191982 98.8% 89.15 103.14 82.16 73.42 216.77 118.87 96.15 77.79 167.82 0.35 0.32 0.70 1.11 0.29 Covered/w/another[2035]
YGL164C YRB30 "RanGTP-binding protein, inhibits RanGAP1 (Rna1p)-mediated GTP hydrolysis of RanGTP (Gsp1p); shares similarity to proteins in other fungi but not in higher eukaryotes" Verified chr7:191984-193306 191984-193306 99.3% 133.94 132.42 116.43 114.15 156.77 112.63 133.18 115.29 134.70 0.49 0.47 0.56 0.22 0.19 Covered/w/another[2035]
YGL163C RAD54 "DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family" Verified chr7:193713-196409 193713-196409 99.1% 86.41 98.38 70.33 62.10 103.62 102.12 92.40 66.21 102.87 0.34 0.27 0.43 0.64 0.94 Covered/w/another[2036]
YGL162W SUT1 Transcription factor of the Zn[II]2Cys6 family involved in sterol uptake; involved in induction of hypoxic gene expression Verified chr7:198144-199043 198144-199043 98.9% 66.29 110.10 68.53 61.79 48.31 43.82 88.19 65.16 46.06 0.33 0.26 0.19 -0.50 -0.17 Covered/w/another[2036]
YGL161C YIP5 "Protein that interacts with Rab GTPases, localized to late Golgi vesicles; computational analysis of large-scale protein-protein interaction data suggests a possible role in vesicle-mediated transport" Verified chr7:199216-200148 199216-200148 99.1% 386.14 328.81 332.06 359.10 589.48 350.44 357.47 345.58 469.96 1.32 1.40 1.95 0.44 0.21 Matched[2037]
YGL160W "Putative protein of uknown function with sequence similarity to iron/copper reductases (FRE1-8), possibly involved in iron homeostasis; may interact with ribosomes, based on co-purification experiments" Verified chr7:200567-202279 200567-202279 99.0% 171.01 172.19 158.04 156.86 227.62 167.47 171.60 157.45 197.55 0.63 0.64 0.82 0.33 0.62 Matched[2038]
YGL159W Putative protein of unknown function; deletion mutant has no detectable phenotype Uncharacterized chr7:202727-203839 202727-203839 99.1% 137.80 128.73 115.14 116.95 131.45 106.07 133.27 116.04 118.76 0.49 0.47 0.49 0.03 -0.02 Matched[2039]
YGL158W RCK1 Protein kinase involved in the response to oxidative stress; identified as suppressor of S. pombe cell cycle checkpoint mutations Verified chr7:207038-208576 207038-208576 98.7% 3.95 6.58 5.27 4.61 7.24 4.61 5.27 4.94 5.93 0.02 0.02 0.02 0.26 0.93
YGL157W "Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol)" Verified chr7:209011-210054 209011-210054 98.9% 298.34 229.57 256.69 192.76 263.47 198.57 263.95 224.72 231.02 0.97 0.91 0.96 0.04 0.15 Matched[2041]
YGL156W AMS1 "Vacuolar alpha mannosidase, involved in free oligosaccharide (fOS) degradation; delivered to the vacuole in a novel pathway separate from the secretory pathway" Verified chr7:210421-213672 210421-213672 98.8% 56.64 95.85 59.75 56.33 227.18 247.10 76.25 58.04 237.14 0.28 0.24 0.98 2.03 2.30 Matched[2042]
YGL155W CDC43 "Beta subunit of geranylgeranyltransferase type I, catalyzes geranylgeranylation to the cysteine residue in proteins containing a C-terminal CaaX sequence ending in Leu or Phe; has substrates important for morphogenesis" Verified chr7:214086-215216 214086-215216 98.8% 184.33 160.17 173.59 134.22 116.32 85.00 172.25 153.90 100.66 0.64 0.62 0.42 -0.61 -0.29 Covered/w/another[2043]
YGL154C LYS5 Phosphopantetheinyl transferase involved in lysine biosynthesis; converts inactive apo-form of Lys2p (alpha-aminoadipate reductase) into catalytically active holo-form by posttranslational addition of phosphopantetheine Verified chr7:215283-216101 215283-216101 99.1% 110.87 144.13 92.39 67.75 149.05 66.52 127.50 80.07 107.79 0.47 0.33 0.45 0.43 0.02 Covered/w/another[2043]
YGL153W PEX14 "Peroxisomal membrane peroxin that is a central component of the peroxisomal protein import machinery; interacts with both PTS1 (Pex5p) and PTS2 (Pex7p), peroxisomal matrix protein signal recognition factors and membrane receptor Pex13p" Verified chr7:216278-217303 216278-217303 98.3% 171.50 169.52 152.66 180.42 250.81 171.50 170.51 166.54 211.15 0.63 0.68 0.87 0.34 0.43 Covered/w/another[2043]
YGL152C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF PEX14/YGL153W" Dubious chr7:216697-217374 216697-217374 98.4% 167.90 172.39 161.90 169.39 262.34 179.89 170.14 165.65 221.11 0.63 0.67 0.92 0.42 0.21 Covered/w/another[2043]
YGL151W NUT1 "Component of the RNA polymerase II mediator complex, which is required for transcriptional activation and also has a role in basal transcription" Verified chr7:217529-220927 217529-220927 99.1% 112.80 130.61 114.28 105.08 127.94 124.97 121.70 109.68 126.45 0.45 0.45 0.52 0.21 0.51 Matched[2044]
YGL149W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF INO80/YGL150C." Dubious chr7:225577-225882 225577-225882 99.5% 59.11 42.69 36.12 32.84 39.41 52.55 50.90 34.48 45.98 0.19 0.14 0.19 0.42 -0.13 Covered/w/another[2045]
YGL150C INO80 "ATPase that forms a large complex, containing actin and several actin-related proteins, that has chromatin remodeling activity and 3' to 5' DNA helicase activity in vitro; shows similarity to the Snf2p family of ATPases" Verified chr7:221109-225578 221109-225578 99.3% 148.97 134.78 123.28 114.94 97.36 106.60 141.88 119.11 101.98 0.52 0.48 0.42 -0.22 0.54 Frag>80[2045,2046]
YGL148W ARO2 "Bifunctional chorismate synthase and flavin reductase, catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids" Verified chr7:226404-227534 226404-227534 98.5% 1234.01 1092.21 1105.68 996.19 284.50 215.39 1163.11 1050.93 249.94 4.29 4.27 1.04 -2.07 -0.66 Matched[2047]
YGL147C RPL9A "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Bp and has similarity to E. coli L6 and rat L9 ribosomal proteins" Verified chr7:227759-228334 227759-228334 53.6% 9366.64 6533.96 7833.63 6780.28 1552.46 1160.30 7950.30 7306.96 1356.38 29.35 29.66 5.62 -2.43 -3.39 Frag>80[2048,2049]
YGL146C "Putative protein of unknown function, contains two putative transmembrane spans, shows no significant homology to any other known protein sequence, YGL146C is not an essential gene" Uncharacterized chr7:228756-229691 228756-229691 99.1% 25.87 38.80 34.49 34.49 49.58 32.34 32.34 34.49 40.96 0.12 0.14 0.17 0.25 0.50 Matched[2050]
YGL145W TIP20 "Peripheral membrane protein required for fusion of COPI vesicles with the ER, prohibits back-fusion of COPII vesicles with the ER, may act as a sensor for vesicles at the ER membrane; interacts with Sec20p" Verified chr7:230248-232353 230248-232353 99.0% 128.54 137.65 117.03 94.00 84.41 51.32 133.09 105.52 67.87 0.49 0.43 0.28 -0.64 -0.51 Covered/w/another[2051]
YGL144C ROG1 Protein with putative serine active lipase domain Verified chr7:232455-234512 232455-234512 99.1% 51.50 51.01 26.49 24.52 19.13 16.19 51.25 25.50 17.66 0.19 0.10 0.07 -0.53 -0.28 Covered/w/another[2051]
YGL143C MRF1 "Mitochondrial translation release factor, involved in stop codon recognition and hydrolysis of the peptidyl-tRNA bond during mitochondrial translation; lack of MRF1 causes mitochondrial genome instability" Verified chr7:234722-235963 234722-235963 99.1% 121.02 136.46 96.66 94.22 113.71 68.23 128.74 95.44 90.97 0.48 0.39 0.38 -0.07 0.00 Covered/w/another[2051]
YGL142C GPI10 "Integral membrane protein involved in glycosylphosphatidylinositol (GPI) anchor synthesis; putative alpha 1,2 mannosyltransferase required for addition of the third mannose onto the GPI core structure; human PIG-Bp is a functional homolog" Verified chr7:236274-238124 236274-238124 98.9% 156.21 153.48 129.99 137.09 136.54 97.77 154.84 133.54 117.15 0.57 0.54 0.49 -0.19 0.24 Covered/w/another[2051]
YGL141W HUL5 "Protein with similarity to hect domain E3 ubiquitin-protein ligases, not essential for viability" Verified chr7:238358-241090 238358-241090 98.8% 64.07 96.67 74.81 80.00 170.37 152.59 80.37 77.41 161.48 0.30 0.31 0.67 1.06 1.12 Matched[2052]
YGL140C Putative protein of unknown function; non-essential gene; contains multiple predicted transmembrane domains Uncharacterized chr7:241358-245017 241358-245017 99.1% 124.40 119.16 109.51 97.09 81.92 89.09 121.78 103.30 85.51 0.45 0.42 0.35 -0.27 0.52 Frag>80[2053]
YGL139W FLC3 "Putative FAD transporter, similar to Flc1p and Flc2p; localized to the ER" Verified chr7:245721-248129 245721-248129 98.9% 174.52 154.81 153.97 149.77 90.20 73.84 164.67 151.87 82.02 0.61 0.62 0.34 -0.89 -0.49 Matched[2054]
YGL138C Putative protein of unknown function; has no significant sequence similarity to any known protein Uncharacterized chr7:248499-249536 248499-249536 99.2% 0.97 0.97 0.00 1.94 0.00 0.00 0.97 0.97 0.00 0.00 0.00 0.00 -Inf -0.12
YGL137W SEC27 "Essential beta'-coat protein of the COPI coatomer, involved in ER-to-Golgi and Golgi-to-ER transport; contains WD40 domains that mediate cargo selective interactions; 45% sequence identity to mammalian beta'-COP" Verified chr7:249874-252743 249874-249891,250092-252743 98.6% 600.39 464.44 557.48 536.97 352.79 404.06 532.41 547.22 378.42 1.97 2.22 1.57 -0.53 -0.16 Matched[2055]
YGL136C MRM2 "Mitochondrial 2' O-ribose methyltransferase, required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ" Verified chr7:252902-253864 252902-253864 99.2% 103.68 147.67 127.77 84.83 180.14 107.87 125.68 106.30 144.00 0.46 0.43 0.60 0.44 0.32 Matched[2056]
YGL135W RPL1B "N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl1Ap and has similarity to E. coli L1 and rat L10a ribosomal proteins; rpl1a rpl1b double null mutation is lethal" Verified chr7:254646-255299 254646-255299 6.5% 7086.61 6118.11 6992.13 4181.10 1440.94 1133.86 6602.36 5586.61 1287.40 24.37 22.68 5.33 -2.12 -2.01 Frag<80[2057,2058,2059,2060]
YGL134W PCL10 "Pho85p cyclin; recruits, activates, and targets Pho85p cyclin-dependent protein kinase to its substrate" Verified chr7:255668-256969 255668-256969 98.7% 99.64 108.20 77.07 77.07 69.28 47.48 103.92 77.07 58.38 0.38 0.31 0.24 -0.40 -0.03 Matched[2061]
YGL133W ITC1 "Component of the ATP-dependent Isw2p-Itc1p chromatin remodeling complex, required for repression of a-specific genes, repression of early meiotic genes during mitotic growth, and repression of INO1" Verified chr7:257712-261506 257712-261506 98.6% 117.28 110.87 92.70 87.09 132.51 157.35 114.07 89.90 144.93 0.42 0.36 0.60 0.69 1.01 Matched[2062]
YGL132W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene SNT2/YGL131C" Dubious chr7:261585-261920 261585-261920 98.9% 54.16 78.23 72.22 78.23 87.26 81.24 66.20 75.23 84.25 0.24 0.31 0.35 0.16 0.25 Covered/w/another[2063]
YGL131C SNT2 DNA binding protein with similarity to the S. pombe Snt2 protein Verified chr7:261653-265864 261653-265864 99.3% 38.27 38.75 32.05 35.64 50.47 70.32 38.51 33.85 60.40 0.14 0.14 0.25 0.84 0.89 Matched[2063]
YGL130W CEG1 "Alpha (guanylyltransferase) subunit of the mRNA capping enzyme, a heterodimer (the other subunit is CET1, an RNA 5'-triphophatase) involved in adding the 5' cap to mRNA; the mammalian enzyme is a single bifunctional polypeptide" Verified chr7:266150-267529 266150-267529 98.6% 141.09 127.86 146.97 130.07 135.21 102.88 134.48 138.52 119.04 0.50 0.56 0.49 -0.22 0.07 Covered/w/another[2064]
YGL129C RSM23 "Mitochondrial ribosomal protein of the small subunit, has similarity to mammalian apoptosis mediator proteins; null mutation prevents induction of apoptosis by overproduction of metacaspase Mca1p" Verified chr7:267728-269194 267728-269194 99.1% 158.14 167.08 177.39 193.89 191.14 189.08 162.61 185.64 190.11 0.60 0.75 0.79 0.03 0.41 Covered/w/another[2064]
YGL128C CWC23 "Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; has similarity to E. coli DnaJ and other DnaJ-like proteins and to S. pombe Cwf23p" Verified chr7:269299-270150 269299-270150 98.6% 60.73 65.49 57.15 48.82 51.20 53.58 63.11 52.99 52.39 0.23 0.22 0.22 -0.02 -0.02 Covered/w/another[2064]
YGL127C SOH1 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; involved in telomere maintenance; conserved with other metazoan MED31 subunits Verified chr7:270398-270781 270398-270781 98.5% 227.26 272.19 224.62 182.34 362.03 240.48 249.72 203.48 301.26 0.92 0.83 1.25 0.57 0.74 Covered/w/another[2064]
YGL126W SCS3 "Protein required for inositol prototrophy, appears to be involved in the synthesis of inositol phospholipids from inositol but not in the control of inositol synthesis" Verified chr7:271003-272145 271003-272145 98.1% 200.62 237.18 202.41 162.28 320.11 217.57 218.90 182.35 268.84 0.81 0.74 1.11 0.56 0.43 Covered/w/another[2065]
YGL125W MET13 "Isozyme of methylenetetrahydrofolate reductase, catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate in the methionine biosynthesis pathway" Verified chr7:272526-274328 272526-274328 98.7% 55.61 110.10 71.91 62.36 105.61 127.52 82.86 67.13 116.56 0.31 0.27 0.48 0.80 1.18 Covered/w/another[2065]
YGL124C MON1 "Protein required for fusion of cvt-vesicles and autophagosomes with the vacuole; associates, as a complex with Ccz1p, with a perivacuolar compartment; potential Cdc28p substrate" Verified chr7:274786-276720 274786-276720 99.3% 57.77 67.66 51.00 37.47 70.26 51.00 62.71 44.24 60.63 0.23 0.18 0.25 0.45 0.39 Covered/w/another[2065]
YGL123W RPS2 "Protein component of the small (40S) subunit, essential for control of translational accuracy; has similarity to E. coli S5 and rat S2 ribosomal proteins" Verified chr7:277623-278387 277623-278387 98.6% 14105.95 11812.41 12867.70 11715.63 2115.89 1686.35 12959.18 12291.67 1901.12 47.84 49.89 7.88 -2.69 -3.99 Frag>80[2066,2067,2068]
YGL123C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene RPS2/YGL123W" Dubious chr7:277640-277870 277640-277870 98.3% 11960.35 10281.94 11074.89 10422.91 1713.66 1493.39 11121.15 10748.90 1603.52 41.05 43.63 6.64 -2.74 NaN Matched[2066]
YGL122C NAB2 Nuclear polyadenylated RNA-binding protein; autoregulates mRNA levels; related to human hnRNPs; has nuclear localization signal sequence that binds to Kap104p; required for poly(A) tail length control and nuclear mRNA export Verified chr7:278952-280529 278952-280529 93.0% 235.69 251.36 333.79 311.99 246.59 289.51 243.53 322.89 268.05 0.90 1.31 1.11 -0.27 0.07 Matched[2069]
YGL121C GPG1 Proposed gamma subunit of the heterotrimeric G protein that interacts with the receptor Grp1p; involved in regulation of pseudohyphal growth; requires Gpb1p or Gpb2p to interact with Gpa2p Verified chr7:280783-281163 280783-281163 99.1% 66.24 535.22 108.63 135.13 922.06 540.52 300.73 121.88 731.29 1.11 0.49 3.03 2.58 1.87 Matched[2070]
YGL120C PRP43 "RNA helicase in the DEAH-box family, functions in both RNA polymerase I and polymerase II transcript metabolism, involved in release of the lariat-intron from the spliceosome" Verified chr7:281640-283943 281640-283943 98.9% 423.38 244.81 292.63 253.59 46.07 44.75 334.10 273.11 45.41 1.23 1.11 0.19 -2.59 -1.72 Frag>80[2071,2072]
YGL119W ABC1 "Protein required for ubiquinone (coenzyme Q) biosynthesis and for respiratory growth; exhibits genetic interaction with COQ9, suggesting a common function; similar to prokaryotic proteins involved in early steps of ubiquinone biosynthesis" Verified chr7:284448-285953 284448-285953 98.6% 94.28 109.76 93.60 98.99 88.89 82.83 102.02 96.30 85.86 0.38 0.39 0.36 -0.17 0.33 Matched[2073]
YGL118C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr7:288020-288457 288020-288457 99.3% 9.20 9.20 6.90 4.60 0.00 2.30 9.20 5.75 1.15 0.03 0.02 0.00 -2.32 -0.39 Overlap[2074]
YGL117W Putative protein of unknown function Uncharacterized chr7:288518-289315 288518-289315 98.9% 97.56 461.17 102.62 122.90 68.42 45.61 279.36 112.76 57.01 1.03 0.46 0.24 -0.98 -1.15 Matched[2074]
YGL116W CDC20 "Cell-cycle regulated activator of anaphase-promoting complex/cyclosome (APC/C), which is required for metaphase/anaphase transition; directs ubiquitination of mitotic cyclins, Pds1p, and other anaphase inhibitors; potential Cdc28p substrate" Verified chr7:289812-291644 289812-291644 98.7% 134.88 123.27 114.98 103.37 112.22 86.79 129.08 109.18 99.50 0.48 0.44 0.41 -0.13 0.26 Matched[2075]
YGL115W SNF4 "Activating gamma subunit of the AMP-activated Snf1p kinase complex (contains Snf1p and a Sip1p/Sip2p/Gal83p family member); activates glucose-repressed genes, represses glucose-induced genes; role in sporulation, and peroxisome biogenesis" Verified chr7:292036-293004 292036-293004 98.9% 364.17 352.70 387.13 326.61 688.70 432.00 358.43 356.87 560.35 1.32 1.45 2.32 0.65 0.71 Matched[2076]
YGL114W Putative protein of unknown function; predicted member of the oligopeptide transporter (OPT) family of membrane transporters Uncharacterized chr7:293463-295640 293463-295640 98.7% 133.95 135.35 125.11 106.97 63.72 57.21 134.65 116.04 60.46 0.50 0.47 0.25 -0.94 -0.40 Matched[2077]
YGL113W SLD3 "Protein involved in the initiation of DNA replication, required for proper assembly of replication proteins at the origins of replication; interacts with Cdc45p" Verified chr7:295935-297941 295935-297941 98.7% 79.77 58.06 56.04 59.07 53.01 37.36 68.91 57.56 45.19 0.25 0.23 0.19 -0.35 0.33 Matched[2078]
YGL112C TAF6 "Subunit (60 kDa) of TFIID and SAGA complexes, involved in transcription initiation of RNA polymerase II and in chromatin modification, similar to histone H4" Verified chr7:298181-299731 298181-299731 99.1% 202.92 180.15 177.55 188.61 130.72 108.61 191.53 183.08 119.67 0.71 0.74 0.50 -0.61 -0.22 Matched[2079]
YGL111W NSA1 "Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis" Verified chr7:299981-301372 299981-301372 98.6% 186.58 110.78 143.58 119.53 32.07 18.22 148.68 131.56 25.15 0.55 0.53 0.10 -2.39 -1.65 Matched[2080]
YGL110C CUE3 "Protein of unknown function; has a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination" Verified chr7:301540-303414 301540-303414 99.4% 132.04 149.75 118.08 118.08 159.95 99.83 140.89 118.08 129.89 0.52 0.48 0.54 0.14 0.21 Matched[2081]
YGL109W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the uncharacterized gene YGL108C" Dubious chr7:303516-303839 303516-303839 99.3% 115.03 189.64 211.40 180.31 338.86 248.70 152.33 195.85 293.78 0.56 0.80 1.22 0.58 0.01 Matched[2082]
YGL108C Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery Uncharacterized chr7:303652-304074 303652-304074 99.4% 137.92 206.88 183.10 183.10 340.04 230.65 172.40 183.10 285.35 0.64 0.74 1.18 0.64 0.65 Matched[2082]
YGL107C RMD9 Mitochondrial protein required for respiratory growth; mutant phenotype and genetic interactions suggest a role in delivering mt mRNAs to ribosomes; located on matrix face of the inner membrane and loosely associated with mitoribosomes Verified chr7:304336-306276 304336-306276 99.1% 127.86 106.03 104.47 96.67 111.22 68.09 116.94 100.57 89.66 0.43 0.41 0.37 -0.17 0.11 Matched[2083]
YGL106W MLC1 "Essential light chain for Myo1p, light chain for Myo2p; stabilizes Myo2p by binding to the neck region; interacts with Myo1p, Iqg1p, and Myo2p to coordinate formation and contraction of the actomyosin ring with targeted membrane deposition" Verified chr7:306563-307012 306563-307012 98.0% 1013.61 1088.44 952.38 909.30 1077.10 673.47 1051.02 930.84 875.28 3.88 3.78 3.63 -0.09 -0.12 Matched[2084]
YGL105W ARC1 "Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases (Mes1p and Gus1p), delivering tRNA to them, stimulating catalysis, and ensuring their localization to the cytoplasm; also binds quadruplex nucleic acids" Verified chr7:307440-308570 307440-308570 98.6% 1860.51 1648.80 1630.86 1734.92 1206.55 965.24 1754.65 1682.89 1085.89 6.48 6.83 4.50 -0.63 -0.40 Matched[2085]
YGL104C VPS73 Mitochondrial protein; mutation affects vacuolar protein sorting; putative transporter; member of the sugar porter family Verified chr7:308716-310176 308716-310176 99.0% 86.38 153.42 114.72 117.48 322.04 261.22 119.90 116.10 291.63 0.44 0.47 1.21 1.33 0.95 Matched[2086]
YGL103W RPL28 "Ribosomal protein of the large (60S) ribosomal subunit, has similarity to E. coli L15 and rat L27a ribosomal proteins; may have peptidyl transferase activity; can mutate to cycloheximide resistance" Verified chr7:310970-311930 310970-311018,311530-311930 98.4% 17462.75 14146.73 15408.58 13006.77 6304.74 5320.54 15804.74 14207.68 5812.64 58.34 57.67 24.08 -1.29 -2.03 Matched[2087]
YGL102C Dubious open reading frame unlikely to encode a functional protein; overlaps 3' end of essential RPL28 gene encoding a large subunit ribosomal protein Dubious chr7:311508-311936 311508-311936 98.4% 18037.30 14712.58 15863.44 13343.86 6467.09 5410.95 16374.94 14603.65 5939.02 60.45 59.28 24.61 -1.30 0.01 Matched[2087]
YGL101W Putative protein of unknown function; non-essential gene with similarity to YBR242W; interacts with the DNA helicase Hpr5p Uncharacterized chr7:312196-312843 312196-312843 98.8% 345.09 268.58 306.05 249.84 115.55 56.21 306.83 277.94 85.88 1.13 1.13 0.36 -1.69 -1.81 Matched[2088]
YGL100W SEH1 "Nuclear pore protein that is part of the evolutionarily conserved Nup84p complex (Nup84p, Nup85p, Nup120p, Nup145p, and Seh1p); homologous to Sec13p" Verified chr7:313237-314286 313237-314286 98.7% 342.47 337.65 342.47 293.27 240.21 203.55 340.06 317.87 221.88 1.26 1.29 0.92 -0.52 -0.19 Matched[2089]
YGL099W LSG1 Putative GTPase involved in 60S ribosomal subunit biogenesis; required for the release of Nmd3p from 60S subunits in the cytoplasm Verified chr7:314634-316556 314634-316556 98.6% 249.38 153.43 183.48 148.15 37.43 22.67 201.41 165.82 30.05 0.74 0.67 0.12 -2.46 -2.08 Matched[2090]
YGL098W USE1 "Essential SNARE protein localized to the ER, involved in retrograde traffic from the Golgi to the ER; forms a complex with the SNAREs Sec22p, Sec20p and Ufe1p" Verified chr7:317345-318082 317345-318082 98.5% 112.84 144.49 148.62 121.09 228.43 115.59 128.66 134.85 172.01 0.47 0.55 0.71 0.35 0.59 Covered[2091]
YGL097W SRM1 "Nucleotide exchange factor for Gsp1p, localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p" Verified chr7:321785-323233 321785-323233 98.4% 344.27 251.02 321.13 300.10 235.59 204.74 297.64 310.61 220.16 1.10 1.26 0.91 -0.50 -0.23 Matched[2093]
YGL096W TOS8 "Homeodomain-containing transcription factor; SBF regulated target gene that in turn regulates expression of genes involved in G1/S phase events such as bud site selection, bud emergence and cell cycle progression; similarity to Cup9p" Verified chr7:325334-326164 325334-326164 98.8% 91.31 192.36 109.57 96.18 477.25 315.32 141.84 102.88 396.29 0.52 0.42 1.64 1.95 1.65 Frag>80[2096,2097]
YGL095C VPS45 "Protein of the Sec1p/Munc-18 family, essential for vacuolar protein sorting; required for the function of Pep12p and the early endosome/late Golgi SNARE Tlg2p; essential for fusion of Golgi-derived vesicles with the prevacuolar compartment" Verified chr7:328877-330610 328877-330610 99.3% 170.68 170.10 176.48 169.52 183.45 121.91 170.39 173.00 152.68 0.63 0.70 0.63 -0.18 0.12 Frag>80[2099,2100]
YGL094C PAN2 "Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex, which acts to control poly(A) tail length and regulate the stoichiometry and activity of postreplication repair complexes" Verified chr7:331121-334468 331121-334468 99.1% 135.29 116.01 110.28 101.24 114.50 112.39 125.65 105.76 113.45 0.46 0.43 0.47 0.10 0.61 Matched[2101]
YGL093W SPC105 "Protein required for accurate chromosome segregation, localizes to the nuclear side of the spindle pole body; forms a complex with Ydr532cp" Verified chr7:334889-337642 334889-337642 98.5% 83.65 90.29 84.76 76.28 157.36 121.24 86.97 80.52 139.30 0.32 0.33 0.58 0.79 0.94 Matched[2102]
YGL092W NUP145 "Essential nucleoporin, catalyzes its own cleavage in vivo to generate a C-terminal fragment that assembles into the Nup84p subcomplex of the nuclear pore complex, and an N-terminal fragment of unknown function that is homologous to Nup100p" Verified chr7:337909-341862 337909-341862 98.8% 205.22 179.63 169.40 156.60 76.25 92.63 192.43 163.00 84.44 0.71 0.66 0.35 -0.95 -0.34 Frag<80[2103]
YGL091C NBP35 Essential iron-sulfur cluster binding protein localized in the cytoplasm; forms a complex with Cfd1p that is involved in iron-sulfur protein assembly in the cytosol; similar to P-loop NTPases Verified chr7:342059-343045 342059-343045 99.1% 131.88 122.68 118.59 94.05 167.66 104.28 127.28 106.32 135.97 0.47 0.43 0.56 0.35 0.26 Covered[2104]
YGL090W LIF1 Protein involved in DNA double-strand break repair; physically interacts with DNA ligase 4 (Lig4p); homologous to mammalian XRCC4 protein Verified chr7:343322-344587 343322-344587 98.3% 65.07 79.53 57.04 53.02 58.64 44.18 72.30 55.03 51.41 0.27 0.22 0.21 -0.10 0.68 Covered/w/another[2105]
YGL089C MF(ALPHA)2 "Mating pheromone alpha-factor, made by alpha cells; interacts with mating type a cells to induce cell cycle arrest and other responses leading to mating; also encoded by MF(ALPHA)1, which is more highly expressed than MF(ALPHA)2" Verified chr7:344794-345156 344794-345156 98.6% 47.50 103.39 58.68 58.68 64.27 47.50 75.45 58.68 55.89 0.28 0.24 0.23 -0.07 -0.05 Covered/w/another[2105]
YGL088W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps snR10, a snoRNA required for preRNA processing" Dubious chr7:345839-346204 345839-346204 99.0% 104.91 74.54 88.35 69.02 66.26 96.63 89.73 78.68 81.44 0.33 0.32 0.34 0.05 -0.03 Frag<80[2106,2107]
YGL087C MMS2 "Protein involved in error-free postreplication DNA repair; forms a heteromeric complex with Ubc13p that has a ubiquitin-conjugating activity; cooperates with chromatin-associated RING finger proteins, Rad18p and Rad5p" Verified chr7:346409-346907 346409-346811,346897-346907 98.9% 342.02 510.59 378.66 354.23 825.73 588.76 426.30 366.45 707.25 1.57 1.49 2.93 0.95 0.84 Matched[2107]
YGL086W MAD1 Coiled-coil protein involved in the spindle-assembly checkpoint; phosphorylated by Mps1p upon checkpoint activation which leads to inhibition of the activity of the anaphase promoting complex; forms a complex with Mad2p Verified chr7:347122-349371 347122-349371 98.7% 208.01 186.40 158.48 157.58 174.24 120.66 197.20 158.03 147.45 0.73 0.64 0.61 -0.10 -0.12 Frag>80[2107,2108,2109]
YGL085W "Putative protein of unknown function, has homology to Staphylococcus aureus nuclease; green fluorescent protein (GFP)-fusion protein localizes to mitochondria and is induced in response to the DNA-damaging agent MMS" Uncharacterized chr7:349619-350443 349619-350443 98.6% 79.92 94.67 81.15 76.23 119.26 73.77 87.30 78.69 96.52 0.32 0.32 0.40 0.29 0.11 Matched[2110]
YGL084C GUP1 Plasma membrane protein with a possible role in proton symport of glycerol; member of the MBOAT family of putative membrane-bound O-acyltransferases Verified chr7:350619-352301 350619-352301 98.9% 287.12 232.46 270.30 272.11 295.53 230.66 259.79 271.21 263.10 0.96 1.10 1.09 -0.04 0.17 Matched[2111]
YGL083W SCY1 "Putative kinase, suppressor of GTPase mutant, similar to bovine rhodopsin kinase" Verified chr7:353061-355475 353061-355475 99.1% 87.34 112.41 94.86 75.64 96.53 63.10 99.87 85.25 79.82 0.37 0.35 0.33 -0.09 -0.04 Matched[2112]
YGL082W Putative protein of unknown function; predicted prenylation/proteolysis target of Afc1p and Rce1p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YGL082W is not an essential gene Uncharacterized chr7:355830-356975 355830-356975 98.6% 310.53 394.57 359.19 368.92 557.36 413.15 352.55 364.05 485.26 1.30 1.48 2.01 0.41 0.70 Matched[2113]
YGL081W "Putative protein of unknown function; non-essential gene; interacts genetically with CHS5, a gene involved in chitin biosynthesis" Uncharacterized chr7:357380-358342 357380-358342 98.3% 22.18 20.06 25.34 30.62 86.59 52.80 21.12 27.98 69.70 0.08 0.11 0.29 1.32 1.60 Matched[2114]
YGL080W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr7:358639-359031 358639-359031 99.1% 346.71 359.55 400.64 369.82 757.62 372.39 353.13 385.23 565.01 1.30 1.56 2.34 0.55 -0.05 Matched[2115]
YGL079W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endosome; identified as a transcriptional activator in a high-throughput yeast one-hybrid assay Uncharacterized chr7:359447-360103 359447-360103 98.9% 149.24 127.70 141.55 110.78 146.16 116.93 138.47 126.16 131.55 0.51 0.51 0.55 0.06 -0.25 Matched[2116]
YGL078C DBP3 Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis Verified chr7:360291-361862 360291-361862 99.2% 564.39 311.70 323.24 298.87 31.43 4.49 438.04 311.06 17.96 1.62 1.26 0.07 -4.11 -3.76 Matched[2117]
YGL077C HNM1 Choline transporter (permease) that also controls the uptake of nitrogen mustard; expression is co-regulated with phospholipid biosynthetic genes and negatively regulated by choline and myo-inositol Verified chr7:362228-363919 362228-363919 98.6% 380.50 315.78 335.56 300.80 188.75 119.84 348.14 318.18 154.30 1.29 1.29 0.64 -1.04 -0.73 Frag>80[2118,2119,2120]
YGL076C RPL7A "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl7Bp and has similarity to E. coli L30 and rat L7 ribosomal proteins; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2)" Verified chr7:364338-365999 364338-364967,365436-365529,365989-365999 27.8% 5910.63 4647.21 5288.72 4157.52 1194.86 1287.90 5278.92 4723.12 1241.38 19.49 19.17 5.14 -1.93 -2.87 Frag>80[2120,2121,2122,2123,2124]
YGL075C MPS2 "Essential membrane protein localized at the nuclear envelope and spindle pole body (SPB), required for insertion of the newly duplicated SPB into the nuclear envelope; potentially phosphorylated by Cdc28p" Verified chr7:366928-368091 366928-368091 99.2% 51.98 53.71 34.65 37.25 63.24 48.51 52.84 35.95 55.88 0.20 0.15 0.23 0.64 0.61 Matched[2125]
YGL073W HSF1 "Trimeric heat shock transcription factor, activates multiple genes in response to stresses that include hyperthermia; recognizes variable heat shock elements (HSEs) consisting of inverted NGAAN repeats; posttranslationally regulated" Verified chr7:368756-371257 368756-371257 98.8% 143.65 141.22 125.44 124.63 244.00 239.55 142.44 125.04 241.78 0.53 0.51 1.00 0.95 1.29 Matched[2126]
YGL074C Dubious open reading frame unlikely to encode a functional protein; overlaps 5' end of essential HSF1 gene encoding heat shock transcription factor Dubious chr7:368599-368925 368599-368925 98.5% 55.89 46.58 59.00 46.58 55.89 65.21 51.24 52.79 60.55 0.19 0.21 0.25 0.20 0.86 Covered/w/another[2126]
YGL072C Dubious open reading frame unlikely to encode a protein; partially overlaps the verified gene HSF1 Dubious chr7:371006-371365 371006-371365 98.3% 206.31 152.61 163.92 135.66 325.01 214.79 179.46 149.79 269.90 0.66 0.61 1.12 0.85 0.12 Covered/w/another[2126]
YGL071W AFT1 Transcription factor involved in iron utilization and homeostasis; binds the consensus site PyPuCACCCPu and activates the expression of target genes in response to changes in iron availability Verified chr7:372015-374087 372015-374087 98.9% 205.33 125.83 166.80 130.22 151.68 161.43 165.58 148.51 156.56 0.61 0.60 0.65 0.08 0.50 Matched[2127]
YGL070C RPB9 RNA polymerase II subunit B12.6; contacts DNA; mutations affect transcription start site; involved in telomere maintenance Verified chr7:374462-374830 374462-374830 98.9% 293.05 328.65 304.01 334.13 221.84 128.72 310.85 319.07 175.28 1.15 1.30 0.73 -0.86 -1.32 Covered/w/another[2127]
YGL068W MNP1 Protein associated with the mitochondrial nucleoid; putative mitochondrial ribosomal protein with similarity to E. coli L7/L12 ribosomal protein; required for normal respiratory growth Verified chr7:375090-375674 375090-375674 98.4% 897.89 889.21 885.74 880.53 963.89 580.07 893.55 883.13 771.98 3.30 3.58 3.20 -0.19 -0.81 Frag>80[2128,2129]
YGL069C "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 92% of ORF overlaps the uncharacterized ORF YGL068W; deletion in cyr1 mutant results in loss of stress resistance" Dubious chr7:375053-375517 375053-375517 98.4% 747.34 823.82 799.78 745.15 847.86 550.67 785.58 772.47 699.26 2.90 3.14 2.90 -0.14 0.06 Frag>80[2128,2129]
YGL067W NPY1 "NADH diphosphatase (pyrophosphatase), hydrolyzes the pyrophosphate linkage in NADH and related nucleotides; localizes to peroxisomes" Verified chr7:376104-377258 376104-377258 99.0% 207.23 180.12 207.23 174.00 140.78 92.68 193.68 190.61 116.73 0.71 0.77 0.48 -0.71 -0.52 Matched[2130]
YGL066W SGF73 73 kDa subunit of SAGA histone acetyltransferase complex; involved in formation of the preinitiation complex assembly at promoters Verified chr7:377612-379585 377612-379585 98.2% 138.84 153.29 122.84 115.61 109.42 86.19 146.06 119.23 97.81 0.54 0.48 0.41 -0.29 -0.08 Covered/w/another[2131]
YGL065C ALG2 Mannosyltransferase that catalyzes two consecutive steps in the N-linked glycosylation pathway; alg2 mutants exhibit temperature-sensitive growth and abnormal accumulation of the lipid-linked oligosaccharide Man2GlcNAc2-PP-Dol Verified chr7:379763-381274 379763-381274 99.2% 176.68 180.01 176.68 158.68 123.34 94.01 178.35 167.68 108.68 0.66 0.68 0.45 -0.63 -0.29 Covered/w/another[2131]
YGL064C MRH4 "Mitochondrial ATP-dependent RNA helicase of the DEAD-box family, plays an essential role in mitochondrial function" Verified chr7:381526-383211 381526-383211 98.9% 57.57 62.37 67.76 50.37 35.98 28.78 59.97 59.07 32.38 0.22 0.24 0.13 -0.87 -0.21 Matched[2132]
YGL063W PUS2 "Mitochondrial tRNA:pseudouridine synthase; acts at positions 27 and 28, but not at position 72; efficiently and rapidly targeted to mitochondria, specifically dedicated to mitochondrial tRNA modification" Verified chr7:383657-384769 383657-384769 98.2% 64.93 69.51 58.53 29.27 47.56 19.21 67.22 43.90 33.38 0.25 0.18 0.14 -0.40 -0.19 Matched[2133]
YGL063C-A "Dubious open reading frame, unlikely to encode a functional protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr7:384505-384654 384505-384654 98.4% 67.74 101.61 54.19 40.64 54.19 20.32 84.67 47.42 37.26 0.31 0.19 0.15 -0.35 NaN Covered/w/another[2133]
YGL062W PYC1 "Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc2p but differentially regulated; mutations in the human homolog are associated with lactic acidosis" Verified chr7:385199-388735 385199-388735 77.9% 185.82 336.44 247.88 225.02 368.38 315.39 261.13 236.45 341.88 0.96 0.96 1.42 0.53 0.77 Frag>80[2134,2135]
YGL061C DUO1 "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis" Verified chr7:388971-389714 388971-389714 99.3% 155.62 110.96 113.67 101.49 82.54 36.54 133.29 107.58 59.54 0.49 0.44 0.25 -0.85 -0.87 Matched[2136]
YGL060W YBP2 "Protein with a role in resistance to oxidative stress; has similarity to Ybp1p, which is involved in regulation of the transcription factor Yap1p via oxidation of specific cysteine residues" Verified chr7:390070-391995 390070-391995 99.1% 100.64 96.97 90.16 90.16 65.52 41.94 98.81 90.16 53.73 0.36 0.37 0.22 -0.75 -0.14 Matched[2137]
YGL059W "Protein kinase; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr7:392228-393703 392228-393703 99.1% 49.24 103.96 48.56 55.40 179.19 128.58 76.60 51.98 153.88 0.28 0.21 0.64 1.57 1.22 Frag>80[2138,2139]
YGL058W RAD6 "Ubiquitin-conjugating enzyme (E2), involved in postreplication repair (with Rad18p), sporulation, telomere silencing, and ubiquitin-mediated N-end rule protein degradation (with Ubr1p)" Verified chr7:393992-394510 393992-394510 96.4% 465.53 423.58 357.64 349.65 607.39 497.50 444.56 353.65 552.45 1.64 1.44 2.29 0.64 0.68 Matched[2140]
YGL057C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant exhibits a growth defect on a non-fermentable (respiratory) carbon source" Uncharacterized chr7:394972-395835 394972-395835 99.0% 92.34 92.34 104.03 80.65 90.01 85.33 92.34 92.34 87.67 0.34 0.37 0.36 -0.07 0.27 Covered/w/another[2141]
YGL056C SDS23 "One of two S. cerevisiae homologs (Sds23p and Sds24p) of the Schizosaccharomyces pombe Sds23 protein, which genetic studies have implicated in APC/cyclosome regulation" Verified chr7:396041-397624 396041-397624 98.7% 204.73 220.73 165.07 147.79 85.73 92.13 212.73 156.43 88.93 0.79 0.63 0.37 -0.81 -0.30 Covered/w/another[2141]
YGL055W OLE1 "Delta(9) fatty acid desaturase, required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria" Verified chr7:398631-400163 398631-400163 98.9% 497.14 3544.62 444.40 465.49 160.22 91.65 2020.88 454.95 125.93 7.46 1.85 0.52 -1.85 -1.46 Matched[2142]
YGL054C ERV14 "Protein localized to COPII-coated vesicles, involved in vesicle formation and incorporation of specific secretory cargo; required for the delivery of bud-site selection protein Axl2p to cell surface; related to Drosophila cornichon" Verified chr7:400874-401290 400874-401290 99.1% 1405.79 1444.50 1459.02 1352.56 2376.05 1364.65 1425.14 1405.79 1870.35 5.26 5.71 7.75 0.41 -0.01 Frag>80[2143,2144,2145,2146]
YGL053W PRM8 "Pheromone-regulated protein with 2 predicted transmembrane segments and an FF sequence, a motif involved in COPII binding; forms a complex with Prp9p in the ER; member of DUP240 gene family" Verified chr7:402592-403305 402592-403305 51.6% 127.49 154.61 141.05 151.90 273.96 254.97 141.05 146.47 264.47 0.52 0.59 1.10 0.85 1.20 Frag<80[2146,2147,2148,2149,2150]
YGL052W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF MST27" Dubious chr7:403440-403745 403440-403745 61.3% 127.91 79.95 117.26 58.63 58.63 53.30 103.93 87.94 55.96 0.38 0.36 0.23 -0.65 0.42 Matched[2149]
YGL051W MST27 "Putative integral membrane protein, involved in vesicle formation; forms complex with Mst28p; member of DUP240 gene family; binds COPI and COPII vesicles" Verified chr7:403690-404394 403690-404394 11.4% 86.82 99.22 111.63 49.61 62.02 37.21 93.02 80.62 49.61 0.34 0.33 0.21 -0.70 -0.05 Frag<80[2149,2150]
YGL050W TYW3 "Protein required for the synthesis of wybutosine, a modified guanosine found at the 3'-position adjacent to the anticodon of phenylalanine tRNA which supports reading frame maintenance by stabilizing codon-anticodon interactions" Verified chr7:405779-406600 405779-406600 98.4% 158.25 121.16 147.13 102.62 97.67 46.98 139.71 124.87 72.33 0.52 0.51 0.30 -0.79 -0.83 Matched[2151]
YGL049C TIF4632 "Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); associates with the poly(A)-binding protein Pab1p, also interacts with eIF4A (Tif1p); homologous to Tif4631p" Verified chr7:406863-409607 406863-409607 99.3% 224.95 261.28 257.61 243.66 189.35 222.38 243.11 250.63 205.87 0.90 1.02 0.85 -0.28 0.18 Matched[2152]
YGL048C RPT6 One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; bound by ubiquitin-protein ligases Ubr1p and Ufd4p; localized mainly to the nucleus throughout the cell cycle Verified chr7:410072-411289 410072-411289 99.2% 644.45 530.28 648.58 578.26 880.22 561.72 587.36 613.42 720.97 2.17 2.49 2.99 0.23 0.35 Frag>80[2153,2154,2155]
YGL047W ALG13 "Catalytic component of UDP-GlcNAc transferase, required for the second step of dolichyl-linked oligosaccharide synthesis; anchored to the ER membrane via interaction with Alg14p; similar to bacterial and human glycosyltransferases" Verified chr7:411555-412163 411555-412163 98.7% 121.45 109.80 169.69 164.70 567.31 324.41 115.62 167.20 445.86 0.43 0.68 1.85 1.42 0.96 Frag>80[2155,2156]
YGL045W RIM8 "Protein of unknown function, involved in the proteolytic activation of Rim101p in response to alkaline pH; has similarity to A. nidulans PalF" Verified chr7:414106-415734 414106-415734 98.6% 49.19 82.81 41.09 45.45 122.04 88.41 66.00 43.27 105.22 0.24 0.18 0.44 1.28 1.31 Frag<80[2157]
YGL044C RNA15 Cleavage and polyadenylation factor I (CF I) component involved in cleavage and polyadenylation of mRNA 3' ends; interacts with the A-rich polyadenylation signal in complex with Rna14p and Hrp1p Verified chr7:416150-417040 416150-417040 99.3% 174.12 162.81 144.72 139.07 143.59 90.45 168.46 141.89 117.02 0.62 0.58 0.48 -0.28 -0.40 Covered[2158]
YGL043W DST1 "General transcription elongation factor TFIIS, enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites" Verified chr7:417487-418416 417487-418416 98.4% 309.19 257.84 240.36 221.79 202.12 205.40 283.52 231.07 203.76 1.05 0.94 0.84 -0.18 0.28 Matched[2159]
YGL042C "Dubious open reading frame, not conserved in closely related Saccharomyces species; deletion mutation blocks replication of Brome mosaic virus in S. cerevisiae, but this is likely due to effects on the overlapping gene DST1" Dubious chr7:418292-418597 418292-418597 98.4% 345.32 292.20 305.48 295.52 325.40 232.43 318.76 300.50 278.92 1.18 1.22 1.16 -0.11 -0.00 Covered/w/another[2159]
YGL041C-B Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr7:418709-418891 418709-418891 98.9% 99.42 93.90 88.38 104.95 143.61 116.00 96.66 96.66 129.80 0.36 0.39 0.54 0.43 NaN Matched[2160]
YGL041W-A Dubious open reading frame unlikely to encode a protein; partially overlaps the dubious ORF YGL041C; identified by expression profiling and mass spectrometry Dubious chr7:419047-419295 419047-419295 98.4% 273.42 199.97 277.50 228.53 603.98 363.20 236.69 253.02 483.59 0.87 1.03 2.00 0.93 NaN Matched[2160]
YGL041C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr7:418917-419231 418917-419231 98.3% 287.33 225.99 258.27 225.99 535.92 322.84 256.66 242.13 429.38 0.95 0.98 1.78 0.83 -0.21 Matched[2160]
YGL040C HEM2 "Delta-aminolevulinate dehydratase, a homo-octameric enzyme, catalyzes the conversion of delta-aminolevulinic acid to porphobilinogen, the second step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus" Verified chr7:419533-420561 419533-420561 98.8% 519.28 524.20 538.95 497.64 460.27 298.98 521.74 518.30 379.63 1.93 2.10 1.57 -0.45 -0.33 Matched[2161]
YGL039W "Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol)" Verified chr7:423967-425013 423967-425013 98.9% 170.01 373.84 184.50 178.71 170.98 88.87 271.93 181.61 129.93 1.00 0.74 0.54 -0.48 -0.01 Covered[2163]
YGL038C OCH1 "Mannosyltransferase of the cis-Golgi apparatus, initiates the polymannose outer chain elongation of N-linked oligosaccharides of glycoproteins" Verified chr7:425368-426810 425368-426810 99.0% 234.53 294.03 242.23 200.92 160.32 89.61 264.28 221.57 124.96 0.98 0.90 0.52 -0.83 -0.64 Frag<80[2164,2165]
YGL037C PNC1 "Nicotinamidase that converts nicotinamide to nicotinic acid as part of the NAD(+) salvage pathway, required for life span extension by calorie restriction; PNC1 expression responds to all known stimuli that extend replicative life span" Verified chr7:427303-427953 427303-427953 98.9% 1368.63 2425.01 2693.77 3013.79 22148.23 15095.35 1896.82 2853.78 18621.79 7.00 11.58 77.16 2.71 1.95 Frag>80[2165,2166]
YGL036W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YGL036W is not an essential gene Uncharacterized chr7:428606-431335 428606-431335 99.1% 130.12 169.30 159.69 162.28 380.37 331.95 149.71 160.98 356.16 0.55 0.65 1.48 1.15 1.07 Matched[2167]
YGL035C MIG1 Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase Verified chr7:431553-433067 431553-433067 98.7% 276.86 373.16 349.09 366.47 303.61 218.68 325.01 357.78 261.15 1.20 1.45 1.08 -0.45 -0.00 Frag>80[2168,2169]
YGL034C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr7:433219-433584 433219-433584 98.6% 5.54 8.31 2.77 2.77 11.08 0.00 6.93 2.77 5.54 0.03 0.01 0.02 1.00 -0.30
YGL033W HOP2 "Meiosis-specific protein that localizes to chromosomes, preventing synapsis between nonhomologous chromosomes and ensuring synapsis between homologs; complexes with Mnd1p to promote homolog pairing and meiotic double-strand break repair" Verified chr7:435630-436356 435630-435684,435755-436356 98.8% 4.62 13.86 4.62 9.24 7.70 6.16 9.24 6.93 6.93 0.03 0.03 0.03 0.00 -0.40 Frag<80[2170,2171]
YGL032C AGA2 "Adhesion subunit of a-agglutinin of a-cells, C-terminal sequence acts as a ligand for alpha-agglutinin (Sag1p) during agglutination, modified with O-linked oligomannosyl chains, linked to anchorage subunit Aga1p via two disulfide bonds" Verified chr7:436575-436838 436575-436838 98.8% 1446.06 2082.79 1929.36 1695.38 410.42 241.65 1764.42 1812.37 326.03 6.51 7.36 1.35 -2.47 -2.71 Matched[2171]
YGL031C RPL24A "Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Bp and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate" Verified chr7:437472-438403 437472-437946,438402-438403 64.9% 10762.19 8603.29 9052.52 7856.72 2113.65 1470.51 9682.74 8454.62 1792.08 35.74 34.32 7.43 -2.24 -3.59 Matched[2172]
YGL030W RPL30 "Protein component of the large (60S) ribosomal subunit, has similarity to rat L30 ribosomal protein; involved in pre-rRNA processing in the nucleolus; autoregulates splicing of its transcript" Verified chr7:439096-439643 439096-439098,439329-439643 98.9% 13885.03 12165.30 11869.67 10566.36 3121.59 2403.18 13025.17 11218.01 2762.38 48.08 45.54 11.45 -2.02 -2.77 Frag>80[2173,2174,2175]
YGL029W CGR1 Protein involved in nucleolar integrity and processing of the pre-rRNA for the 60S ribosome subunit; transcript is induced in response to cytotoxic stress but not genotoxic stress Verified chr7:440068-440430 440068-440430 97.7% 580.76 391.87 338.31 287.56 53.57 42.29 486.32 312.93 47.93 1.80 1.27 0.20 -2.71 -3.50 Matched[2176]
YGL028C SCW11 Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on its regulation by Ste12p Verified chr7:441286-442914 441286-442914 95.6% 456.39 478.86 392.84 264.46 184.23 111.69 467.62 328.65 147.96 1.73 1.33 0.61 -1.15 -0.59 Matched[2177]
YGL027C CWH41 "Processing alpha glucosidase I, ER type II integral membrane N-glycoprotein involved in assembly of cell wall beta 1,6 glucan and asparagine-linked protein glycosylation; also involved in ER protein quality control and sensing of ER stress" Verified chr7:443647-446148 443647-446148 99.3% 237.99 250.48 229.14 221.89 107.92 80.94 244.24 225.51 94.43 0.90 0.92 0.39 -1.26 -0.57 Matched[2178]
YGL026C TRP5 "Tryptophan synthase involved in tryptophan biosynthesis, regulated by the general control system of amino acid biosynthesis" Verified chr7:446417-448540 446417-448540 98.8% 650.28 898.49 602.64 675.06 373.02 397.79 774.39 638.85 385.41 2.86 2.59 1.60 -0.73 0.06 Frag>80[2179,2180]
YGL024W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially/completely overlaps the verified ORF PGD1/YGL025C" Dubious chr7:449793-450128 449793-450128 98.7% 45.21 57.26 51.24 51.24 45.21 45.21 51.24 51.24 45.21 0.19 0.21 0.19 -0.18 -0.23 Covered/w/another[2181]
YGL025C PGD1 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for basal and activated transcription; direct target of Cyc8p-Tup1p transcriptional corepressor Verified chr7:448769-449962 448769-449962 98.3% 109.89 139.71 123.52 118.41 90.30 69.85 124.80 120.97 80.08 0.46 0.49 0.33 -0.60 -0.23 Matched[2181]
YGL023C PIB2 "Protein binding phosphatidylinositol 3-phosphate, involved in telomere-proximal repression of gene expression; similar to Fab1 and Vps27" Verified chr7:450202-452109 450202-452109 98.9% 128.80 135.16 133.57 103.36 143.64 144.70 131.98 118.46 144.17 0.49 0.48 0.60 0.28 0.70 Matched[2182]
YGL022W STT3 "Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; forms a subcomplex with Ost3p and Ost4p and is directly involved in catalysis" Verified chr7:452409-454565 452409-454565 98.8% 694.60 660.34 752.33 658.00 413.01 486.69 677.47 705.16 449.85 2.50 2.86 1.86 -0.65 0.05 Matched[2183]
YGL021W ALK1 Protein kinase; accumulation and phosphorylation are periodic during the cell cycle; phosphorylated in response to DNA damage; contains characteristic motifs for degradation via the APC pathway; similar to Alk2p and to mammalian haspins Verified chr7:454790-457072 454790-457072 99.0% 170.40 214.67 146.06 123.05 150.93 110.21 192.53 134.55 130.57 0.71 0.55 0.54 -0.04 0.12 Matched[2184]
YGL020C GET1 Subunit of the GET complex; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for normal mitochondrial morphology and inheritance Verified chr7:457168-457875 457168-457875 99.1% 521.46 558.50 495.81 473.02 411.75 273.55 539.98 484.42 342.65 1.99 1.97 1.42 -0.50 -0.59 Matched[2185]
YGL019W CKB1 "Beta regulatory subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKA2 and CKB2, the many substrates include transcription factors and all RNA polymerases" Verified chr7:458161-458997 458161-458997 98.1% 440.72 371.33 396.90 402.98 484.55 379.85 406.03 399.94 432.20 1.50 1.62 1.79 0.11 0.35 Matched[2186]
YGL018C JAC1 "Specialized J-protein that functions with Hsp70 in Fe-S cluster biogenesis in mitochondria, involved in iron metabolism; contains a J domain typical to J-type chaperones; localizes to the mitochondrial matrix" Verified chr7:459115-459669 459115-459669 99.0% 103.71 120.09 65.50 105.53 172.86 151.02 111.90 85.52 161.94 0.41 0.35 0.67 0.92 0.65 Covered/w/another[2187]
YGL017W ATE1 "Arginyl-tRNA-protein transferase, catalyzes post-translational conjugation of arginine to the amino termini of acceptor proteins which are then subject to degradation via the N-end rule pathway" Verified chr7:459859-461370 459859-461370 98.6% 70.40 87.17 70.40 75.10 98.56 81.13 78.78 72.75 89.85 0.29 0.30 0.37 0.30 0.63 Covered/w/another[2187]
YGL016W KAP122 "Karyopherin beta, responsible for import of the Toa1p-Toa2p complex into the nucleus; binds to nucleoporins Nup1p and Nup2p; may play a role in regulation of pleiotropic drug resistance" Verified chr7:461671-464916 461671-464916 99.1% 115.29 100.06 89.81 60.29 40.09 22.06 107.68 75.05 31.08 0.40 0.30 0.13 -1.27 -0.63 Covered/w/another[2187]
YGL015C Hypothetical protein Uncharacterized chr7:465048-465440 465048-465440 99.0% 18.00 15.43 12.86 5.14 2.57 15.43 16.71 9.00 9.00 0.06 0.04 0.04 0.00 0.37 Overlap[2187]
YGL014W PUF4 "Member of the PUF protein family, which is defined by the presence of Pumilio homology domains that confer RNA binding activity; preferentially binds mRNAs encoding nucleolar ribosomal RNA-processing factors" Verified chr7:466146-468812 466146-468812 98.2% 282.21 262.35 312.00 289.46 125.26 158.10 272.28 300.73 141.68 1.01 1.22 0.59 -1.09 -0.25 Matched[2188]
YGL014C-A "Dubious open reading frame, unlikely to encode a functional protein; identified by expression profiling and mass spectrometry" Dubious chr7:466242-466403 466242-466403 99.4% 161.49 198.76 217.39 267.08 43.48 124.22 180.12 242.24 83.85 0.66 0.98 0.35 -1.53 NaN Covered/w/another[2188]
YGL013C PDR1 Zinc cluster protein that is a master regulator involved in recruiting other zinc cluster proteins to pleiotropic drug response elements (PDREs) to fine tune the regulation of multidrug resistance genes Verified chr7:469097-472303 469097-472303 98.7% 90.63 84.63 80.84 65.05 79.26 70.73 87.63 72.94 75.00 0.32 0.30 0.31 0.04 0.62 Matched[2189]
YGL012W ERG4 "C-24(28) sterol reductase, catalyzes the final step in ergosterol biosynthesis; mutants are viable, but lack ergosterol" Verified chr7:472860-474281 472860-474281 98.8% 932.25 1063.90 838.31 845.43 604.89 422.71 998.07 841.87 513.80 3.68 3.42 2.13 -0.71 -0.50 Matched[2190]
YGL011C SCL1 Alpha subunit of the 20S core complex of the 26S proteasome involved in the degradation of ubiquitinated substrates; essential for growth; detected in the mitochondria Verified chr7:474494-475252 474494-475252 99.1% 820.21 650.05 829.51 782.98 1458.29 1055.50 735.13 806.25 1256.90 2.71 3.27 5.21 0.64 0.81 Frag>80[2191,2192]
YGL010W Putative protein of unknown function; YGL010W is not an essential gene Uncharacterized chr7:475550-476074 475550-476074 99.0% 111.58 121.20 157.76 165.45 671.42 357.84 116.39 161.60 514.63 0.43 0.66 2.13 1.67 0.73 Matched[2193]
YGL009C LEU1 "Isopropylmalate isomerase, catalyzes the second step in the leucine biosynthesis pathway" Verified chr7:476318-478657 476318-478657 99.0% 942.72 733.80 703.15 703.58 225.32 184.74 838.26 703.37 205.03 3.09 2.86 0.85 -1.78 -1.23 Matched[2194]
YGL008C PMA1 "Plasma membrane H+-ATPase, pumps protons out of the cell; major regulator of cytoplasmic pH and plasma membrane potential; part of the P2 subgroup of cation-transporting ATPases" Verified chr7:479915-482671 479915-482671 88.7% 6806.67 6934.25 5988.86 5210.30 1749.71 2622.32 6870.46 5599.58 2186.02 25.36 22.73 9.06 -1.36 -1.77 Frag>80[2195,2196,2197]
YGL007C-A "Putative protein of unknown function, identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; haploid deletion strain exhibits a slow-growth phenotype" Uncharacterized chr7:482946-483032 482946-483032 99.0% 11.61 11.61 34.82 11.61 23.21 69.63 11.61 23.21 46.42 0.04 0.09 0.19 1.00 NaN Covered/w/another[2198]
YGL007W BRP1 "Dubious ORF located in the upstream region of PMA1, deletion leads to polyamine resistance due to downregulation of PMA1" Dubious chr7:483265-483642 483265-483642 98.5% 8.06 18.80 13.43 13.43 16.12 13.43 13.43 13.43 14.78 0.05 0.05 0.06 0.14 0.44 Covered/w/another[2198]
YGL006W-A Putative protein of unknown function; identified by SAGE Uncharacterized chr7:485428-485538 485428-485538 99.3% 9.07 54.44 36.29 27.22 36.29 9.07 31.76 31.76 22.68 0.12 0.13 0.09 -0.49 NaN Covered/w/another[2199]
YGL006W PMC1 Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions; prevents growth inhibition by activation of calcineurin in the presence of elevated concentrations of calcium; similar to mammalian PMCA1a Verified chr7:485925-489446 485925-489446 98.8% 180.97 230.09 240.43 233.25 246.75 313.39 205.53 236.84 280.07 0.76 0.96 1.16 0.24 0.80 Covered/w/another[2199]
YGL005C COG7 "Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" Verified chr7:489712-490551 489712-490551 99.5% 183.09 196.25 161.55 167.53 235.74 160.35 189.67 164.54 198.05 0.70 0.67 0.82 0.27 0.13 Covered/w/another[2199]
YGL004C RPN14 Putative non-ATPase subunit of the 19S regulatory particle of the 26S proteasome; localized to the cytoplasm Uncharacterized chr7:490707-491960 490707-491960 99.3% 107.64 113.27 115.68 98.81 244.21 174.32 110.46 107.24 209.26 0.41 0.44 0.87 0.96 1.19 Covered/w/another[2199]
YGL003C CDH1 "Cell-cycle regulated activator of the anaphase-promoting complex/cyclosome (APC/C), which directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to specific substrates including CDC20, ASE1, CIN8 and FIN1" Verified chr7:492478-494178 492478-494178 99.0% 90.86 102.73 84.33 70.67 100.95 66.51 96.80 77.50 83.73 0.36 0.31 0.35 0.11 0.28 Matched[2200]
YGL002W ERP6 "Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr7:494521-495171 494521-495171 98.7% 270.92 255.35 277.15 266.25 342.55 258.47 263.14 271.70 300.51 0.97 1.10 1.25 0.15 0.14 Frag>80[2201,2202]
YGL001C ERG26 "C-3 sterol dehydrogenase, catalyzes the second of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis" Verified chr7:495457-496506 495457-496506 99.2% 487.93 558.05 440.87 411.09 389.96 326.57 522.99 425.98 358.27 1.93 1.73 1.48 -0.25 -0.14 Matched[2203]
YGR001C Putative protein of unknown function with similarity to methyltransferase family members; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; required for replication of Brome mosaic virus in S. cerevisiae Uncharacterized chr7:497137-498038 497137-497369,497463-497941,498004-498038 99.2% 351.04 303.78 299.73 264.63 306.48 163.37 327.41 282.18 234.92 1.21 1.15 0.97 -0.26 -0.33 Matched[2205]
YGR002C SWC4 Component of the Swr1p complex that incorporates Htz1p into chromatin; component of the NuA4 histone acetyltransferase complex Verified chr7:498480-499910 498480-499910 99.0% 129.17 141.16 110.11 119.99 151.05 126.34 135.16 115.05 138.69 0.50 0.47 0.57 0.27 0.83 Matched[2206]
YGR003W CUL3 "Ubiquitin-protein ligase, member of the cullin family with similarity to Cdc53p and human CUL3; required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21" Verified chr7:500136-502370 500136-502370 98.8% 47.53 38.48 32.14 28.97 25.80 21.28 43.01 30.56 23.54 0.16 0.12 0.10 -0.38 -0.14 Matched[2207]
YGR004W PEX31 "Peroxisomal integral membrane protein, involved in negative regulation of peroxisome size; partially functionally redundant with Pex30p and Pex32p; probably acts at a step downstream of steps mediated by Pex28p and Pex29p" Verified chr7:502942-504330 502942-504330 98.8% 75.75 75.02 69.92 64.09 42.97 41.51 75.38 67.01 42.24 0.28 0.27 0.18 -0.67 -0.06 Matched[2208]
YGR005C TFG2 TFIIF (Transcription Factor II) middle subunit; involved in both transcription initiation and elongation of RNA polymerase II; homologous to human RAP30 Verified chr7:504661-505863 504661-505863 99.5% 277.45 296.67 277.45 289.15 242.35 213.10 287.06 283.30 227.72 1.06 1.15 0.94 -0.32 -0.12 Matched[2209]
YGR006W PRP18 "Splicing factor involved in the positioning of the 3' splice site during the second catalytic step of splicing, part of snRNP U5, interacts with Slu7p" Verified chr7:506074-506829 506074-506829 98.8% 52.22 60.25 38.83 29.46 38.83 42.85 56.23 34.14 40.84 0.21 0.14 0.17 0.26 0.81 Matched[2210]
YGR007W MUQ1 "Choline phosphate cytidylyltransferase, catalyzes the second step of phosphatidylethanolamine biosynthesis; involved in the maintenance of plasma membrane; similar to mammalian CTP: phosphocholine cytidylyl-transferases" Verified chr7:506973-507944 506973-507944 98.6% 332.81 393.32 296.30 268.13 245.17 126.24 363.07 282.21 185.71 1.34 1.15 0.77 -0.60 -0.35 Matched[2211]
YGR008C STF2 Protein involved in regulation of the mitochondrial F1F0-ATP synthase; Stf1p and Stf2p act as stabilizing factors that enhance inhibitory action of the Inh1p protein Verified chr7:508114-508368 508114-508368 99.3% 1035.06 2876.05 2046.42 1927.90 20195.55 9761.98 1955.56 1987.16 14978.77 7.22 8.07 62.06 2.91 1.27 Matched[2212]
YGR009C SEC9 t-SNARE protein important for fusion of secretory vesicles with the plasma membrane; similar to but not functionally redundant with Spo20p; SNAP-25 homolog Verified chr7:509051-511006 509051-511006 99.3% 210.00 200.22 226.47 224.92 265.07 191.47 205.11 225.70 228.27 0.76 0.92 0.95 0.02 0.31 Matched[2214]
YGR010W NMA2 "Nicotinic acid mononucleotide adenylyltransferase, involved in NAD(+) salvage pathway" Verified chr7:511549-512736 511549-512736 98.8% 119.29 113.32 109.92 115.03 173.82 128.66 116.31 112.47 151.24 0.43 0.46 0.63 0.43 0.57 Matched[2215]
YGR011W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr7:512501-512827 512501-512827 98.9% 151.55 188.66 185.57 188.66 262.89 170.10 170.10 187.11 216.49 0.63 0.76 0.90 0.21 0.53 Frag<80[2216]
YGR012W "Putative cysteine synthase, localized to the mitochondrial outer membrane" Verified chr7:513163-514344 513163-514344 98.5% 117.67 146.02 143.44 96.20 125.40 116.81 131.84 119.82 121.11 0.49 0.49 0.50 0.02 0.54 Covered/w/another[2217]
YGR013W SNU71 "Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counterpart" Verified chr7:514558-516420 514558-516420 98.3% 120.08 108.08 106.98 86.24 121.18 94.98 114.08 96.61 108.08 0.42 0.39 0.45 0.16 0.52 Covered/w/another[2217]
YGR014W MSB2 Mucin family member involved in the Cdc42p- and MAP kinase-dependent filamentous growth signaling pathway; also functions as an osmosensor in parallel to the Sho1p-mediated pathway; potential Cdc28p substrate Verified chr7:516947-520867 516947-520867 93.4% 322.35 311.43 321.26 244.22 79.50 90.70 316.89 282.74 85.10 1.17 1.15 0.35 -1.73 -1.00 Frag<80[2218]
YGR015C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion Uncharacterized chr7:521094-522080 521094-522080 99.0% 92.08 103.34 66.50 46.04 76.74 51.16 97.71 56.27 63.95 0.36 0.23 0.26 0.18 -0.20 Matched[2219]
YGR016W Putative protein of unknown function Uncharacterized chr7:522265-522837 522265-522837 99.1% 52.84 51.08 31.70 26.42 79.26 26.42 51.96 29.06 52.84 0.19 0.12 0.22 0.86 0.08 Matched[2220]
YGR017W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the cytoplasm Uncharacterized chr7:523791-524684 523791-524684 98.6% 474.44 442.66 464.22 450.60 464.22 254.24 458.55 457.41 359.23 1.69 1.86 1.49 -0.35 -0.51 Matched[2221]
YGR018C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YGR017W" Dubious chr7:524369-524698 524369-524698 98.3% 511.88 499.55 518.05 474.88 542.72 268.28 505.72 496.47 405.50 1.87 2.02 1.68 -0.29 -0.29 Matched[2221]
YGR019W UGA1 Gamma-aminobutyrate (GABA) transaminase (4-aminobutyrate aminotransferase) involved in the 4-aminobutyrate and glutamate degradation pathways; required for normal oxidative stress tolerance and nitrogen utilization Verified chr7:525233-526648 525233-526648 98.8% 180.89 279.56 209.49 190.90 464.74 282.42 230.23 200.20 373.58 0.85 0.81 1.55 0.90 0.87 Covered/w/another[2222]
YGR020C VMA7 "Subunit F of the eight-subunit V1 peripheral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane" Verified chr7:526977-527333 526977-527333 98.9% 2211.68 2492.04 2189.03 2138.05 1750.09 1444.25 2351.86 2163.54 1597.17 8.68 8.78 6.62 -0.44 -0.58 Covered/w/another[2222]
YGR021W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr7:527636-528508 527636-528508 98.2% 173.81 146.98 166.81 127.15 234.47 165.65 160.40 146.98 200.06 0.59 0.60 0.83 0.44 0.60 Matched[2223]
YGR023W MTL1 "Protein with both structural and functional similarity to Mid2p, which is a plasma membrane sensor required for cell integrity signaling during pheromone-induced morphogenesis; suppresses rgd1 null mutations" Verified chr7:529268-530923 529268-530923 97.7% 59.32 66.12 62.41 57.47 314.53 272.51 62.72 59.94 293.52 0.23 0.24 1.22 2.29 1.88 Matched[2224]
YGR022C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps almost completely with the verified ORF MTL1/YGR023W" Dubious chr7:529261-529590 529261-529590 99.1% 58.08 64.20 73.37 76.42 195.64 235.38 61.14 74.89 215.51 0.23 0.30 0.89 1.52 0.34 Covered/w/another[2224]
YGR024C THG1 "tRNAHis guanylyltransferase, adds a guanosine residue to the 5' end of tRNAHis after transcription and RNase P cleavage; couples nuclear division and migration to cell budding and cytokinesis; essential enzyme conserved among eukaryotes" Verified chr7:531887-532600 531887-532600 99.2% 352.80 419.12 389.49 365.50 296.35 248.37 385.96 377.49 272.36 1.42 1.53 1.13 -0.47 -0.67 Matched[2225]
YGR025W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr7:532643-532945 532643-532945 99.1% 219.91 276.55 216.58 226.57 163.27 179.93 248.23 221.57 171.60 0.92 0.90 0.71 -0.37 -0.28 Overlap[2226]
YGR026W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery Uncharacterized chr7:532989-533825 532989-533825 99.0% 940.30 1199.82 955.99 1003.07 1179.30 937.89 1070.06 979.53 1058.59 3.95 3.98 4.39 0.11 0.31 Matched[2226]
YGR027C RPS25A Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Bp and has similarity to rat S25 ribosomal protein Verified chr7:534136-534790 534136-534477,534789-534790 76.9% 14492.99 12119.07 12954.48 11363.05 5314.85 5587.02 13306.03 12158.76 5450.94 49.12 49.35 22.59 -1.16 -1.89 Matched[2227]
YGR028W MSP1 Mitochondrial protein involved in sorting of proteins in the mitochondria; putative membrane-spanning ATPase Verified chr7:542207-543295 542207-543295 98.7% 190.71 200.01 200.01 209.31 461.41 270.71 195.36 204.66 366.06 0.72 0.83 1.52 0.84 0.29 Matched[2230]
YGR029W ERV1 "Flavin-linked sulfhydryl oxidase of the mitochondrial intermembrane space (IMS), oxidizes Mia40p as part of a disulfide relay system that promotes IMS retention of imported proteins; ortholog of human hepatopoietin (ALR)" Verified chr7:543557-544209 543557-543642,543726-544209 98.3% 274.88 314.15 289.16 298.08 324.85 194.56 294.51 293.62 259.71 1.09 1.19 1.08 -0.18 -0.56 Matched[2231]
YGR030C POP6 "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends" Verified chr7:545685-546161 545685-546161 99.4% 134.91 153.89 118.05 82.21 37.94 25.30 144.40 100.13 31.62 0.53 0.41 0.13 -1.66 1.55 Matched[2232]
YGR031W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr7:546445-547473 546445-547473 98.3% 120.64 137.45 143.39 156.24 138.44 96.91 129.05 149.81 117.68 0.48 0.61 0.49 -0.35 -0.05 Matched[2233]
YGR031C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the uncharacterized ORF YGR031W" Dubious chr7:546813-547304 546813-547304 98.4% 140.40 146.59 156.92 167.24 150.72 101.17 143.50 162.08 125.95 0.53 0.66 0.52 -0.36 NaN Matched[2233]
YGR032W GSC2 "Catalytic subunit of 1,3-beta-glucan synthase, involved in formation of the inner layer of the spore wall; activity positively regulated by Rho1p and negatively by Smk1p; has similarity to an alternate catalytic subunit, Fks1p (Gsc1p)" Verified chr7:548268-553955 548268-553955 96.9% 67.86 111.95 62.59 72.39 37.56 33.20 89.90 67.49 35.38 0.33 0.27 0.15 -0.93 -0.41 Frag>80[2234,2235]
YGR033C TIM21 Constituent of the mitochondrial inner membrane presequence translocase (TIM23 complex); may regulate protein import by binding to both the translocase of the outer membrane (TOM) and presequence-associated motor (PAM) complexes Verified chr7:554252-554971 554252-554971 99.0% 304.49 312.91 318.52 280.64 328.34 182.41 308.70 299.58 255.38 1.14 1.22 1.06 -0.23 -0.51 Matched[2236]
YGR034W RPL26B "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Ap and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA" Verified chr7:555816-556676 555816-555834,556312-556676 71.5% 10478.62 8276.62 9794.36 8327.57 1495.91 1241.13 9377.62 9060.96 1368.52 34.62 36.78 5.67 -2.73 -4.03 Matched[2237]
YGR035C "Putative protein of unknown function, potential Cdc28p substrate; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance" Uncharacterized chr7:557076-557426 557076-557426 98.9% 244.78 198.70 287.98 213.10 51.84 40.32 221.74 250.54 46.08 0.82 1.02 0.19 -2.44 -1.68 Covered/w/another[2238]
YGR035W-A Putative protein of unknown function Uncharacterized chr7:557569-557790 557569-557790 99.0% 163.79 200.19 122.84 68.25 113.74 95.55 181.99 95.55 104.64 0.67 0.39 0.43 0.13 NaN Covered/w/another[2238]
YGR036C CAX4 "Dolichyl pyrophosphate (Dol-P-P) phosphatase with a luminally oriented active site in the ER, cleaves the anhydride linkage in Dol-P-P, required for Dol-P-P-linked oligosaccharide intermediate synthesis and protein N-glycosylation" Verified chr7:558153-558872 558153-558872 98.8% 109.65 129.33 95.59 78.72 113.86 81.53 119.49 87.16 97.70 0.44 0.35 0.40 0.16 0.56 Covered/w/another[2238]
YGR037C ACB1 "Acyl-CoA-binding protein, transports newly synthesized acyl-CoA esters from fatty acid synthetase (Fas1p-Fas2p) to acyl-CoA-consuming processes" Verified chr7:559735-559998 559735-559998 99.2% 2474.86 3253.98 2211.33 2196.05 1913.43 1099.94 2864.42 2203.69 1506.68 10.57 8.95 6.24 -0.55 -1.02 Matched[2240]
YGR038W ORM1 "Evolutionarily conserved protein with similarity to Orm2p, required for resistance to agents that induce the unfolded protein response; human ortholog is located in the endoplasmic reticulum" Verified chr7:560686-561354 560686-561354 99.0% 310.94 295.85 282.26 253.58 264.15 163.02 303.40 267.92 213.58 1.12 1.09 0.88 -0.33 -0.19 Matched[2241]
YGR039W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the Autonomously Replicating Sequence ARS722" Dubious chr7:574892-575203 574892-575203 99.2% 29.08 32.31 25.85 12.92 48.47 22.62 30.69 19.39 35.54 0.11 0.08 0.15 0.87 0.68 Covered/w/another[2242]
YGR040W KSS1 Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains Verified chr7:575402-576508 575402-576508 98.8% 150.00 154.57 138.11 109.76 70.43 52.13 152.29 123.93 61.28 0.56 0.50 0.25 -1.02 -0.80 Covered/w/another[2242]
YGR041W BUD9 "Protein involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern, and bud at the distal pole" Verified chr7:577491-579134 577491-579134 98.7% 179.99 162.73 134.37 87.53 92.46 60.41 171.36 110.95 76.43 0.63 0.45 0.32 -0.54 -0.88 Covered/w/another[2242]
YGR042W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus Uncharacterized chr7:579480-580295 579480-580295 98.6% 156.58 185.16 151.61 155.34 170.25 98.17 170.87 153.47 134.21 0.63 0.62 0.56 -0.19 0.46 Covered/w/another[2242]
YGR043C Protein of unknown function; transcription is repressed by Mot1p and induced by alpha-factor and during diauxic shift; null mutant non-quiescent cells exhibit reduced reproductive capacity Uncharacterized chr7:580439-581440 580439-581440 99.2% 17.11 40.26 23.15 8.05 1325.45 1019.50 28.68 15.60 1172.47 0.11 0.06 4.86 6.23 3.68 Frag>80[2243,2244]
YGR044C RME1 Zinc finger protein involved in control of meiosis; prevents meiosis by repressing IME1 expression and promotes mitosis by activating CLN2 expression; directly repressed by a1-a2 regulator; mediates cell type control of sporulation Verified chr7:582994-583896 582994-583896 98.9% 278.95 434.67 303.60 293.52 729.31 533.26 356.81 298.56 631.28 1.32 1.21 2.62 1.08 1.21 Matched[2246]
YGR045C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr7:583938-584300 583938-584300 98.9% 55.72 47.36 52.94 13.93 66.87 75.23 51.54 33.43 71.05 0.19 0.14 0.29 1.09 -0.85 Covered/w/another[2246]
YGR046W TAM41 Mitochondrial protein involved in protein import into the mitochondrial matrix; maintains the functional integrity of the TIM23 protein translocator complex; viability of null mutant is strain-dependent; mRNA is targeted to the bud Verified chr7:584899-586056 584899-586056 98.8% 133.73 131.10 129.36 144.22 162.57 143.34 132.42 136.79 152.96 0.49 0.56 0.63 0.16 0.32 Matched[2247]
YGR047C TFC4 One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA domain of TFIIIC that binds BoxA DNA promoter sites of tRNA and similar genes; has TPR motifs; human homolog is TFIIIC-102 Verified chr7:586396-589473 586396-589473 99.3% 94.92 79.53 61.86 62.84 53.68 46.15 87.23 62.35 49.91 0.32 0.25 0.21 -0.32 -0.08 Matched[2248]
YGR048W UFD1 "Protein that interacts with Cdc48p and Npl4p, involved in recognition of polyubiquitinated proteins and their presentation to the 26S proteasome for degradation; involved in transporting proteins from the ER to the cytosol" Verified chr7:589830-590915 589830-590915 98.5% 172.88 156.06 197.18 141.11 306.52 235.50 164.47 169.15 271.01 0.61 0.69 1.12 0.68 0.81 Covered/w/another[2249]
YGR049W SCM4 "Potential regulatory effector of CDC4 function, suppresses a temperature-sensitive allele of CDC4, tripartite protein structure in which a charged region separates two uncharged domains, not essential for mitosis or meiosis" Verified chr7:591318-591881 591318-591881 98.8% 218.83 636.77 193.72 222.42 159.64 121.97 427.80 208.07 140.81 1.58 0.84 0.58 -0.56 -0.14 Covered/w/another[2249]
YGR050C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr7:592090-592446 592090-592446 98.8% 36.87 51.05 82.24 82.24 201.35 90.75 43.96 82.24 146.05 0.16 0.33 0.61 0.83 0.31 Covered/w/another[2249]
YGR051C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YGR051C is not an essential gene" Dubious chr7:592910-593233 592910-593233 98.3% 43.98 59.69 53.40 40.84 47.12 15.71 51.83 47.12 31.41 0.19 0.19 0.13 -0.58 1.29 Covered/w/another[2249]
YGR052W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr7:593600-594709 593600-594709 98.9% 10.02 16.40 19.13 28.24 451.82 314.27 13.21 23.68 383.04 0.05 0.10 1.59 4.02 3.68 Matched[2250]
YGR053C Putative protein of unknown function Uncharacterized chr7:594990-595841 594990-595841 99.4% 42.51 59.04 49.59 38.96 121.62 56.68 50.77 44.28 89.15 0.19 0.18 0.37 1.01 0.50 Matched[2251]
YGR054W "Eukaryotic initiation factor (eIF) 2A; associates specifically with both 40S subunits and 80 S ribosomes, and interacts genetically with both eIF5b and eIF4E; homologous to mammalian eIF2A" Verified chr7:596697-598625 596697-598625 98.8% 368.74 303.70 325.20 303.70 163.13 178.34 336.22 314.45 170.73 1.24 1.28 0.71 -0.88 -0.19 Matched[2252]
YGR055W MUP1 "High affinity methionine permease, integral membrane protein with 13 putative membrane-spanning regions; also involved in cysteine uptake" Verified chr7:599421-601145 599421-601145 98.9% 240.98 413.94 303.72 221.04 172.38 138.96 327.46 262.38 155.67 1.21 1.07 0.64 -0.75 -0.07 Matched[2253]
YGR056W RSC1 "Component of the RSC chromatin remodeling complex; required for expression of mid-late sporulation-specific genes; contains two essential bromodomains, a bromo-adjacent homology (BAH) domain, and an AT hook" Verified chr7:601665-604451 601665-604451 98.9% 103.75 106.29 103.03 83.80 74.01 66.39 105.02 93.42 70.20 0.39 0.38 0.29 -0.41 0.06 Covered/w/another[2254]
YGR057C LST7 Protein possibly involved in a post-Golgi secretory pathway; required for the transport of nitrogen-regulated amino acid permease Gap1p from the Golgi to the cell surface Verified chr7:604777-605505 604777-605505 99.3% 82.90 110.53 73.23 66.32 66.32 59.41 96.71 69.77 62.86 0.36 0.28 0.26 -0.15 -0.04 Covered/w/another[2254]
YGR058W PEF1 "Penta-EF-hand protein required for polar bud growth and cell wall abscission; binds calcium and zinc with different affinity; localizes to bud site in G1, bud neck in G2" Verified chr7:606140-607147 606140-607147 98.8% 75.29 57.22 71.28 41.16 47.18 42.16 66.26 56.22 44.67 0.24 0.23 0.19 -0.33 0.25 Matched[2255]
YGR059W SPR3 Sporulation-specific homolog of the yeast CDC3/10/11/12 family of bud neck microfilament genes; septin protein involved in sporulation; regulated by ABFI Verified chr7:607567-609105 607567-609105 98.7% 6.59 4.61 5.27 5.27 7.90 21.08 5.60 5.27 14.49 0.02 0.02 0.06 1.46 0.54 Frag<80[2256,2257]
YGR060W ERG25 "C-4 methyl sterol oxidase, catalyzes the first of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants accumulate the sterol intermediate 4,4-dimethylzymosterol" Verified chr7:610568-611497 610568-611497 99.1% 1307.06 2482.87 1195.34 1083.61 509.81 402.42 1894.97 1139.47 456.11 7.00 4.63 1.89 -1.32 -0.77 Matched[2259]
YGR061C ADE6 "Formylglycinamidine-ribonucleotide (FGAM)-synthetase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway" Verified chr7:611893-615969 611893-615969 99.0% 871.45 551.65 749.08 628.44 114.19 93.39 711.55 688.76 103.79 2.63 2.80 0.43 -2.73 -1.93 Frag<80[2260]
YGR062C COX18 "Mitochondrial inner membrane protein, required for export of the Cox2p C terminus from the mitochondrial matrix to the intermembrane space during its assembly into cytochrome c oxidase; similar to Oxa2p of N. crassa" Verified chr7:616332-617282 616332-617282 98.7% 134.22 177.89 155.52 106.52 127.82 83.09 156.05 131.02 105.45 0.58 0.53 0.44 -0.31 -0.17 Covered/w/another[2261]
YGR064W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF SPT4/YGR063C" Dubious chr7:617625-617993 617625-617993 99.2% 319.71 275.99 273.26 221.34 314.24 122.96 297.85 247.30 218.60 1.10 1.00 0.91 -0.18 -1.00 Covered/w/another[2261]
YGR063C SPT4 "Protein that forms a complex with Spt5p and mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing; in addition, Spt4p is involved in kinetochore function and gene silencing" Verified chr7:617520-617828 617520-617828 99.2% 427.41 384.99 424.14 290.38 430.67 189.23 406.20 357.26 309.95 1.50 1.45 1.28 -0.20 -0.75 Covered/w/another[2261]
YGR065C VHT1 High-affinity plasma membrane H+-biotin (vitamin H) symporter; mutation results in fatty acid auxotrophy; 12 transmembrane domain containing major facilitator subfamily member; mRNA levels negatively regulated by iron deprivation and biotin Verified chr7:618081-619862 618081-619862 98.9% 81.10 83.37 72.60 58.42 33.46 27.79 82.24 65.51 30.63 0.30 0.27 0.13 -1.10 -0.58 Covered/w/another[2261]
YGR066C Putative protein of unknown function Uncharacterized chr7:620925-621803 620925-621803 99.0% 18.38 40.20 14.93 16.08 198.71 119.45 29.29 15.51 159.08 0.11 0.06 0.66 3.36 3.93 Matched[2262]
YGR067C Putative protein of unknown function; contains a zinc finger motif similar to that of Adr1p Uncharacterized chr7:622406-624790 622406-624790 98.9% 9.33 7.63 6.79 6.79 22.90 15.27 8.48 6.79 19.08 0.03 0.03 0.08 1.49 1.62 Frag<80[2263,2264]
YGR068W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps with the uncharacterized ORF YGR068C" Dubious chr7:626298-626393 626298-626393 99.0% 147.30 115.74 52.61 73.65 73.65 84.17 131.52 63.13 78.91 0.49 0.26 0.33 0.32 NaN Covered/w/another[2265]
YGR069W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr7:627087-627422 627087-627422 94.3% 28.41 59.97 37.87 18.94 69.44 18.94 44.19 28.41 44.19 0.16 0.12 0.18 0.64 0.35 Covered/w/another[2265]
YGR068C Putative protein of unknown function; YGR068C is not an essential gene. Uncharacterized chr7:625328-627088 625328-627088 98.9% 90.75 98.79 87.30 66.62 94.19 94.77 94.77 76.96 94.48 0.35 0.31 0.39 0.30 1.17 Matched[2265]
YGR070W ROM1 "GDP/GTP exchange protein (GEP) for Rho1p; mutations are synthetically lethal with mutations in rom2, which also encodes a GEP" Verified chr7:627810-631277 627810-631277 99.0% 52.72 74.86 67.87 78.93 266.81 289.82 63.79 73.40 278.31 0.24 0.30 1.15 1.92 1.66 Matched[2266]
YGR071C Putative protein of unknown function; deletion mutant has increased glycogen accumulation; green fluorescent protein (GFP)-fusion protein localizes to the nucleus Uncharacterized chr7:631485-634067 631485-634067 99.1% 73.06 76.97 61.34 58.60 63.29 48.06 75.01 59.97 55.67 0.28 0.24 0.23 -0.11 -0.70 Matched[2267]
YGR072W UPF3 "Component of the nonsense-mediated mRNA decay (NMD) pathway, along with Nam7p and Nmd2p; involved in decay of mRNA containing nonsense codons; involved in telomere maintenance" Verified chr7:634308-635471 634308-635471 98.4% 180.68 153.62 136.17 122.20 103.00 91.65 167.15 129.18 97.32 0.62 0.52 0.40 -0.41 -0.24 Covered/w/another[2268]
YGR074W SMD1 "Core Sm protein Sm D1; part of heteroheptameric complex (with Smb1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm D1" Verified chr7:635716-636156 635716-636156 98.8% 339.81 305.37 351.29 245.67 257.15 123.98 322.59 298.48 190.57 1.19 1.21 0.79 -0.65 -1.11 Covered/w/another[2268]
YGR073C "Dubious open reading frame unlikely to encode a functional protein, extensively overlaps essential SMD1 gene encoding a U6 snRNP protein" Dubious chr7:635619-635990 635619-635990 98.9% 250.11 220.21 263.71 171.27 187.58 106.03 235.16 217.49 146.81 0.87 0.88 0.61 -0.57 0.06 Covered/w/another[2268]
YGR075C PRP38 "Unique component of the U4/U6.U5 tri-snRNP particle, dispensable for spliceosome assembly, but required for conformational changes which lead to catalytic activation of the spliceosome" Verified chr7:636151-636879 636151-636879 99.4% 160.06 171.09 135.22 125.56 118.66 81.41 165.57 130.39 100.03 0.61 0.53 0.41 -0.38 0.11 Frag<80[2269]
YGR076C MRPL25 Mitochondrial ribosomal protein of the large subunit Verified chr7:637108-637581 637108-637581 99.0% 281.23 236.48 276.96 240.75 423.97 317.44 258.85 258.85 370.71 0.96 1.05 1.54 0.52 0.24 Covered/w/another[2270]
YGR077C PEX8 "Intraperoxisomal organizer of the peroxisomal import machinery, tightly associated with the lumenal face of the peroxisomal membrane, essential for peroxisome biogenesis, binds PTS1-signal receptor Pex5p" Verified chr7:637748-639517 637748-639517 98.9% 140.58 148.58 129.15 101.15 160.58 136.58 144.58 115.15 148.58 0.53 0.47 0.62 0.37 0.88 Covered/w/another[2270]
YGR078C PAC10 "Part of the heteromeric co-chaperone GimC/prefoldin complex, which promotes efficient protein folding" Verified chr7:639776-640375 639776-640375 99.1% 274.06 242.12 237.07 230.35 124.42 102.56 258.09 233.71 113.49 0.95 0.95 0.47 -1.04 -0.74 Covered/w/another[2270]
YGR079W Putative protein of unknown function; YGR079W is not an essential gene Uncharacterized chr7:640724-641836 640724-641836 98.6% 116.65 131.23 54.68 37.36 7.29 6.38 123.94 46.02 6.84 0.46 0.19 0.03 -2.75 -2.77 Matched[2271]
YGR080W TWF1 "Twinfilin, highly conserved actin monomer-sequestering protein involved in regulation of the cortical actin cytoskeleton, composed of two cofilin-like regions, localizes actin monomers to sites of rapid filament assembly" Verified chr7:642014-643012 642014-643012 98.7% 213.99 247.45 222.10 245.43 328.59 297.15 230.72 233.76 312.87 0.85 0.95 1.30 0.42 0.72 Matched[2272]
YGR081C SLX9 Protein required for pre-rRNA processing; associated with the 90S pre-ribosome and 43S small ribosomal subunit precursor; interacts with U3 snoRNA; deletion mutant has synthetic fitness defect with an sgs1 deletion mutant Verified chr7:643152-643784 643152-643784 99.4% 211.35 149.37 149.37 143.02 49.26 20.66 180.36 146.20 34.96 0.67 0.59 0.14 -2.06 -1.56 Matched[2273]
YGR082W TOM20 Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; acts as a receptor for incoming precursor proteins Verified chr7:644048-644599 644048-644599 98.6% 722.09 575.10 687.18 602.66 376.67 264.58 648.60 644.92 320.62 2.39 2.62 1.33 -1.01 -0.74 Covered/w/another[2274]
YGR083C GCD2 "Delta subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression" Verified chr7:644864-646819 644864-646819 99.1% 373.52 294.59 261.57 244.55 90.80 105.25 334.06 253.06 98.02 1.23 1.03 0.41 -1.37 -1.04 Covered/w/another[2274]
YGR084C MRP13 Mitochondrial ribosomal protein of the small subunit Verified chr7:647127-648146 647127-648146 99.2% 232.27 239.19 220.41 228.32 166.05 147.27 235.73 224.36 156.66 0.87 0.91 0.65 -0.52 -0.23 Covered/w/another[2274]
YGR085C RPL11B "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl11Ap; involved in ribosomal assembly; depletion causes degradation of proteins and RNA of the 60S subunit; has similarity to E. coli L5 and rat L11" Verified chr7:648387-648911 648387-648911 23.0% 4022.11 2753.28 3217.69 2114.72 746.37 215.62 3387.70 2666.21 481.00 12.51 10.82 1.99 -2.47 -3.12 Frag<80[2275]
YGR086C PIL1 "Primary component of eisosomes, which are large immobile cell cortex structures associated with endocytosis; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways; detected in phosphorylated state in mitochondria" Verified chr7:649602-650621 649602-650621 99.1% 2314.98 2192.26 2898.92 2810.84 6775.70 5221.82 2253.62 2854.88 5998.76 8.32 11.59 24.85 1.07 0.38 Frag>80[2276,2277,2278]
YGR087C PDC6 "Minor isoform of pyruvate decarboxylase, key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde, regulation is glucose- and ethanol-dependent, involved in amino acid catabolism" Verified chr7:651294-652985 651294-652985 97.6% 6.06 8.48 3.03 3.63 13.93 10.90 7.27 3.33 12.42 0.03 0.01 0.05 1.90 1.87
YGR088W CTT1 "Cytosolic catalase T, has a role in protection from oxidative damage by hydrogen peroxide" Verified chr7:654638-656326 654638-656326 98.8% 33.55 56.92 46.74 59.32 3864.69 4018.67 45.24 53.03 3941.68 0.17 0.22 16.33 6.22 4.79 Matched[2281]
YGR089W NNF2 "Protein that exhibits physical and genetic interactions with Rpb8p, which is a subunit of RNA polymerases I, II, and III; computational analysis of large-scale protein-protein interaction data suggests a role in chromosome segregation" Verified chr7:656964-659774 656964-659774 99.0% 141.51 145.82 112.06 100.21 61.78 55.31 143.67 106.13 58.54 0.53 0.43 0.24 -0.86 -0.30 Matched[2282]
YGR090W UTP22 "Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data" Verified chr7:662362-666075 662362-666075 99.1% 210.11 163.63 150.31 107.37 40.77 30.99 186.87 128.84 35.88 0.69 0.52 0.15 -1.84 -1.26 Matched[2284]
YGR091W PRP31 "Splicing factor, component of the U4/U6-U5 snRNP complex" Verified chr7:666345-667829 666345-667829 98.7% 73.72 49.15 61.43 44.37 43.69 22.53 61.43 52.90 33.11 0.23 0.21 0.14 -0.68 -0.77 Covered/w/another[2285]
YGR092W DBF2 Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis Verified chr7:668193-669911 668193-669911 98.7% 126.11 166.77 161.47 126.11 209.79 127.29 146.44 143.79 168.54 0.54 0.58 0.70 0.23 0.65 Covered/w/another[2285]
YGR093W Putative debranching enzyme associated ribonuclease; green fluorescent protein (GFP)-fusion protein localizes to the nucleus Uncharacterized chr7:670392-671915 670392-671915 98.8% 121.57 95.00 100.98 73.74 51.15 38.53 108.28 87.36 44.84 0.40 0.35 0.19 -0.96 -0.57 Matched[2286]
YGR094W VAS1 Mitochondrial and cytoplasmic valyl-tRNA synthetase Verified chr7:672190-675504 672190-675504 98.8% 1140.12 933.66 955.96 955.65 281.29 256.86 1036.89 955.80 269.07 3.83 3.88 1.11 -1.83 -1.00 Matched[2287]
YGR095C RRP46 Protein involved in rRNA processing; component of the exosome 3->5 exonuclease complex Verified chr7:675675-676346 675675-676346 99.1% 243.27 181.70 157.68 129.15 79.59 64.57 212.49 143.41 72.08 0.78 0.58 0.30 -0.99 -1.01 Covered/w/another[2288]
YGR096W TPC1 Mitochondrial membrane transporter that mediates uptake of the essential cofactor thiamine pyrophosphate (ThPP) into mitochondria; expression appears to be regulated by carbon source; member of the mitochondrial carrier family Verified chr7:676625-677569 676625-677569 98.6% 48.29 59.03 38.64 38.64 31.12 18.24 53.66 38.64 24.68 0.20 0.16 0.10 -0.65 -0.47 Covered/w/another[2288]
YGR097W ASK10 "Component of the RNA polymerase II holoenzyme, phosphorylated in response to oxidative stress; has a role in destruction of Ssn8p, which relieves repression of stress-response genes" Verified chr7:678699-682139 678699-682139 98.9% 94.63 115.79 88.46 84.64 80.82 134.60 105.21 86.55 107.71 0.39 0.35 0.45 0.32 0.84 Covered/w/another[2288]
YGR098C ESP1 Separase with cysteine protease activity (related to caspases) that promotes sister chromatid separation by mediating dissociation of the cohesin Scc1p from chromatin; inhibited by Pds1p Verified chr7:682570-687462 682570-687462 99.1% 64.33 61.44 59.79 53.40 45.36 60.82 62.88 56.60 53.09 0.23 0.23 0.22 -0.09 0.15 Frag>80[2289]
YGR099W TEL2 "Essential DNA-binding protein specific to single-stranded yeast telomeric DNA repeats, required for telomere length regulation and telomere position effect" Verified chr7:687903-689969 687903-689969 98.7% 74.02 76.47 62.75 69.61 72.55 59.81 75.25 66.18 66.18 0.28 0.27 0.27 0.00 0.28 Matched[2290]
YGR100W MDR1 "Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p, Ypt31p and Sec4p; involved in recycling of internalized proteins and regulation of Golgi secretory function" Verified chr7:690249-693101 690249-693101 98.7% 118.62 131.40 125.01 110.45 142.41 136.38 125.01 117.73 139.39 0.46 0.48 0.58 0.24 0.81 Covered/w/another[2291]
YGR101W PCP1 Mitochondrial serine protease required for the processing of various mitochondrial proteins and maintenance of mitochondrial DNA and morphology; belongs to the rhomboid-GlpG superfamily of intramembrane peptidases Verified chr7:693367-694407 693367-694407 98.8% 104.97 106.91 118.58 108.86 149.68 106.91 105.94 113.72 128.30 0.39 0.46 0.53 0.17 0.12 Covered/w/another[2291]
YGR102C "Putative protein of unknown function; transposon insertion mutant is salt sensitive and deletion mutant has growth defects; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr7:694588-695139 694588-695139 99.1% 146.21 202.86 129.76 148.04 263.17 191.90 174.54 138.90 227.54 0.64 0.56 0.94 0.71 0.71 Covered/w/another[2291]
YGR103W NOP7 Nucleolar protein involved in rRNA processing and 60S ribosomal subunit biogenesis; constituent of several different pre-ribosomal particles; required for exit from G0 and the initiation of cell proliferation Verified chr7:695421-697238 695421-697238 98.5% 710.53 263.45 505.13 426.43 54.70 15.07 486.99 465.78 34.88 1.80 1.89 0.14 -3.74 -2.62 Matched[2292]
YGR104C SRB5 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in telomere maintenance Verified chr7:697449-698372 697449-698372 99.3% 122.10 97.03 92.67 51.24 81.77 76.32 109.57 71.95 79.04 0.40 0.29 0.33 0.14 0.30 Matched[2293]
YGR105W VMA21 "Integral membrane protein that is required for vacuolar H+-ATPase (V-ATPase) function, although not an actual component of the V-ATPase complex; functions in the assembly of the V-ATPase; localized to the yeast endoplasmic reticulum (ER)" Verified chr7:698603-698836 698603-698836 98.9% 903.13 868.56 760.53 630.90 566.08 324.09 885.85 695.71 445.08 3.27 2.82 1.84 -0.64 -1.95 Matched[2294]
YGR106C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuolar memebrane Uncharacterized chr7:698993-699790 698993-699790 99.0% 1814.02 2022.89 1722.88 1748.19 1110.19 775.99 1918.46 1735.53 943.09 7.08 7.04 3.91 -0.88 -1.09 Matched[2295]
YGR107W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr7:702671-703120 702671-703120 99.1% 4.49 6.73 13.46 6.73 33.65 11.22 5.61 10.10 22.43 0.02 0.04 0.09 1.15 0.37 Matched[2298]
YGR108W CLB1 "B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome" Verified chr7:703640-705055 703640-705055 98.6% 368.89 416.16 330.93 254.28 168.33 104.58 392.53 292.60 136.45 1.45 1.19 0.57 -1.10 -0.84 Matched[2299]
YGR109C CLB6 B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1 Verified chr7:705363-706505 705363-706505 99.1% 72.39 61.80 73.27 42.37 17.66 19.42 67.09 57.82 18.54 0.25 0.23 0.08 -1.64 -1.25 Matched[2300]
YGR110W Putative protein of unknown function; transcription is increased in response to genotoxic stress Uncharacterized chr7:713713-715050 713713-715050 98.8% 25.71 32.51 18.90 15.88 72.59 56.71 29.11 17.39 64.65 0.11 0.07 0.27 1.89 2.58 Matched[2302]
YGR111W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus Uncharacterized chr7:715832-717034 715832-717034 98.7% 174.37 246.81 220.70 192.90 711.80 443.93 210.59 206.80 577.87 0.78 0.84 2.39 1.48 1.58 Matched[2303]
YGR112W SHY1 "Mitochondrial inner membrane protein required for normal respiration, possible chaperone involved in assembly of cytochrome c oxidase; similar to SURF1 from mammals, chickens, and D. melanogaster" Verified chr7:717362-718531 717362-718531 98.5% 66.83 96.34 78.12 92.00 170.12 98.95 81.59 85.06 134.53 0.30 0.35 0.56 0.66 1.11 Matched[2304]
YGR113W DAM1 "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; Ipl1p target for regulating kinetochore-MT attachments" Verified chr7:718897-719928 718897-719928 98.6% 205.30 202.36 181.73 192.53 199.41 126.72 203.83 187.13 163.06 0.75 0.76 0.68 -0.20 0.18 Matched[2305]
YGR116W SPT6 Essential protein that interacts with histones and is involved in nucleosome disassembly and reassembly during transcription elongation Verified chr7:720413-724768 720413-724768 98.7% 381.10 318.98 333.64 345.27 212.42 258.02 350.04 339.45 235.22 1.29 1.38 0.97 -0.53 -0.19 Matched[2307]
YGR114C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; open reading frame overlaps 5' end of the essential gene SPT6" Dubious chr7:720269-720658 720269-720658 97.6% 330.85 257.33 257.33 249.45 236.32 291.47 294.09 253.39 263.89 1.09 1.03 1.09 0.06 -0.11 Covered/w/another[2307]
YGR115C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified and essential ORF SPT6/YGR115C" Dubious chr7:720376-721155 720376-721155 97.8% 329.05 267.44 266.13 289.73 201.89 267.44 298.25 277.93 234.66 1.10 1.13 0.97 -0.24 -0.10 Covered/w/another[2307]
YGR117C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr7:725053-726483 725053-726483 99.2% 152.83 166.21 145.78 133.11 161.28 102.12 159.52 139.44 131.70 0.59 0.57 0.55 -0.08 -0.07 Matched[2308]
YGR118W RPS23A "Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit, required for translational accuracy; nearly identical to Rps23Bp and similar to E. coli S12 and rat S23 ribosomal proteins; deletion of both RPS23A and RPS23B is lethal" Verified chr7:726978-727735 726978-727042,727363-727735 44.1% 6450.00 5244.83 5586.21 4753.45 3051.72 1924.14 5847.41 5169.83 2487.93 21.59 20.99 10.31 -1.06 -3.14 Matched[2309]
YGR119C NUP57 "Nucleoporin, essential subunit of the nuclear pore complex (NPC), functions as the organizing center of an NPC subcomplex containing Nsp1p, Nup49p, Nup57p, and Nic96p" Verified chr7:728051-729676 728051-729676 99.2% 414.33 380.21 328.73 318.19 289.04 222.67 397.27 323.46 255.85 1.47 1.31 1.06 -0.34 -0.31 Covered/w/another[2310]
YGR120C COG2 "Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" Verified chr7:730038-730826 730038-730826 99.1% 76.71 120.18 92.05 70.32 109.95 56.25 98.44 81.18 83.10 0.36 0.33 0.34 0.03 0.06 Covered/w/another[2310]
YGR121C MEP1 Ammonium permease; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation Verified chr7:731454-732932 731454-732932 98.8% 91.00 112.21 89.63 95.79 80.05 65.00 101.61 92.71 72.53 0.38 0.38 0.30 -0.35 0.54 Matched[2311]
YGR121W-A Putative protein of unknown function Uncharacterized chr7:733417-733632 733417-733632 98.8% 9.37 9.37 4.69 9.37 4.69 28.11 9.37 7.03 16.40 0.03 0.03 0.07 1.22 NaN Covered/w/another[2311]
YGR122W Putative protein of unknown function; deletion mutants do not properly process Rim101p and have decreased resistance to rapamycin; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr7:733940-735148 733940-735148 98.9% 106.17 130.41 91.96 89.45 86.11 52.67 118.29 90.70 69.39 0.44 0.37 0.29 -0.39 -0.09 Matched[2312]
YGR122C-A "Dubious open reading frame unlikely to encode a functional protein, similar to YLR334C and YOL106W" Dubious chr7:735635-735763 735635-735763 46.1% 33.66 67.32 67.32 16.83 16.83 84.15 50.49 42.08 50.49 0.19 0.17 0.21 0.26 -0.16 Matched[2313]
YGR123C PPT1 Protein serine/threonine phosphatase with similarity to human phosphatase PP5; present in both the nucleus and cytoplasm; expressed during logarithmic growth Verified chr7:736667-738208 736667-738208 99.2% 227.47 132.04 164.07 151.65 16.99 11.11 179.75 157.86 14.05 0.66 0.64 0.06 -3.49 -2.60 Matched[2314]
YGR124W ASN2 "Asparagine synthetase, isozyme of Asn1p; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway" Verified chr7:739949-741667 739949-741667 90.6% 1291.79 1001.45 1154.97 1168.46 374.50 350.09 1146.62 1161.72 362.29 4.23 4.72 1.50 -1.68 -1.17 Matched[2315]
YGR125W Putative protein of unknown function; deletion mutant has decreased rapamycin resistance but normal wormannin resistance; green fluorescent protein (GFP)-fusion protein localizes to the vacuole Uncharacterized chr7:742330-745440 742330-745440 98.9% 118.00 139.77 101.74 105.32 111.17 109.87 128.89 103.53 110.52 0.48 0.42 0.46 0.09 0.68 Matched[2316]
YGR126W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus and is induced in response to the DNA-damaging agent MMS Uncharacterized chr7:745840-746532 745840-746532 98.7% 26.32 36.55 29.24 20.47 52.63 27.78 31.43 24.86 40.21 0.12 0.10 0.17 0.69 0.12 Matched[2317]
YGR127W "Putative protein of unknown function; expression is regulated by Msn2p/Msn4p, indicating a possible role in stress response" Uncharacterized chr7:746803-747741 746803-747741 98.8% 134.67 143.29 151.91 119.59 741.25 547.32 138.98 135.75 644.28 0.51 0.55 2.67 2.25 2.22 Matched[2318]
YGR128C UTP8 Nucleolar protein required for export of tRNAs from the nucleus; also copurifies with the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA Verified chr7:747955-750096 747955-750096 99.2% 206.17 135.10 126.62 122.39 13.65 1.88 170.64 124.50 7.77 0.63 0.51 0.03 -4.00 -2.23 Matched[2319]
YGR129W SYF2 Component of the spliceosome complex involved in pre-mRNA splicing; involved in regulation of cell cycle progression Verified chr7:750405-751052 750405-751052 98.0% 72.47 75.62 74.04 69.32 59.87 63.02 74.04 71.68 61.44 0.27 0.29 0.25 -0.22 -0.43 Covered/w/another[2320]
YGR130C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; specifically phosphorylated in vitro by mammalian diphosphoinositol pentakisphosphate (IP7) Uncharacterized chr7:751399-753849 751399-753849 98.4% 319.77 398.98 473.22 529.21 1045.57 1024.00 359.38 501.22 1034.79 1.33 2.03 4.29 1.05 1.39 Covered/w/another[2320]
YGR131W "Protein of unknown function; expression induced in response to ketoconazole; promoter region contains a sterol regulatory element motif, which has been identified as a Upc2p-binding site" Uncharacterized chr7:754731-755255 754731-755255 98.8% 25.06 46.27 25.06 15.42 94.47 57.84 35.67 20.24 76.16 0.13 0.08 0.32 1.91 1.46 Covered/w/another[2320]
YGR132C PHB1 "Subunit of the prohibitin complex (Phb1p-Phb2p), a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation" Verified chr7:755594-756457 755594-756457 99.2% 736.18 681.35 698.85 735.02 1144.52 743.18 708.76 716.93 943.85 2.62 2.91 3.91 0.40 0.60 Covered/w/another[2320]
YGR133W PEX4 Peroxisomal ubiquitin conjugating enzyme required for peroxisomal matrix protein import and peroxisome biogenesis Verified chr7:756901-757452 756901-757452 98.6% 97.34 104.69 86.32 78.98 176.32 84.49 101.02 82.65 130.40 0.37 0.34 0.54 0.66 0.16 Covered/w/another[2320]
YGR134W CAF130 "Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation" Verified chr7:757775-761143 757775-761143 98.8% 61.59 50.78 46.27 41.16 45.37 35.75 56.18 43.72 40.56 0.21 0.18 0.17 -0.11 0.24 Covered/w/another[2320]
YGR135W PRE9 20S proteasome beta-type subunit; the only nonessential 20S subunit Verified chr7:761397-762173 761397-762173 98.5% 1128.49 881.63 1088.00 965.22 1673.14 843.76 1005.06 1026.61 1258.45 3.71 4.17 5.21 0.29 -0.08 Covered/w/another[2320]
YGR136W LSB1 "Protein containing an N-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization" Verified chr7:762433-763158 762433-763158 98.8% 370.88 407.13 361.12 365.31 1544.88 1254.87 389.01 363.21 1399.87 1.44 1.47 5.80 1.95 1.86 Covered/w/another[2320]
YGR137W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr7:762893-763267 762893-763267 98.7% 434.79 507.71 415.89 321.37 1809.38 1396.20 471.25 368.63 1602.79 1.74 1.50 6.64 2.12 1.89 Covered/w/another[2320]
YGR138C TPO2 Polyamine transport protein specific for spermine; localizes to the plasma membrane; transcription of TPO2 is regulated by Haa1p; member of the major facilitator superfamily Verified chr7:763767-765611 763767-765611 38.7% 152.77 294.32 57.46 54.66 32.24 72.88 223.55 56.06 52.56 0.83 0.23 0.22 -0.09 -0.12 Frag<80[2321]
YGR139W "Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr7:765731-766069 765731-766069 98.8% 74.65 95.56 20.90 20.90 14.93 44.79 85.11 20.90 29.86 0.31 0.08 0.12 0.51 -0.02 Matched[2321]
YGR140W CBF2 "Essential kinetochore protein, component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere; Cbf2p also binds to the CDEII region possibly forming a different multimeric complex, ubiquitinated in vivo" Verified chr7:767434-770304 767434-770304 98.9% 70.42 61.26 46.12 40.84 46.83 31.69 65.84 43.48 39.26 0.24 0.18 0.16 -0.15 -0.80 Frag>80[2322]
YGR141W VPS62 Vacuolar protein sorting (VPS) protein required for cytoplasm to vacuole targeting of proteins Verified chr7:770574-771977 770574-771977 98.3% 109.41 131.88 121.73 113.76 413.02 273.17 120.64 117.75 343.10 0.45 0.48 1.42 1.54 -1.21 Frag>80[2323,2324]
YGR142W BTN2 "v-SNARE binding protein that facilitates specific protein retrieval from a late endosome to the Golgi; modulates arginine uptake, possible role in mediating pH homeostasis between the vacuole and plasma membrane H(+)-ATPase" Verified chr7:772459-773691 772459-773691 98.5% 78.21 67.51 89.73 97.14 11137.65 6564.54 72.86 93.44 8851.10 0.27 0.38 36.67 6.57 4.97 Matched[2325]
YGR143W SKN1 Protein involved in sphingolipid biosynthesis; type II membrane protein with similarity to Kre6p Verified chr7:775198-777513 775198-777513 98.1% 161.16 189.34 176.13 151.03 242.62 209.59 175.25 163.58 226.10 0.65 0.66 0.94 0.47 0.88 Matched[2327]
YGR144W THI4 "Thiazole synthase, catalyzes formation of the thiazole moiety of thiamin pyrophosphate; required for thiamine biosynthesis and for mitochondrial genome stability" Verified chr7:780404-781384 780404-781384 98.8% 15.47 11.35 2.06 12.38 16.51 6.19 13.41 7.22 11.35 0.05 0.03 0.05 0.65 0.36 Frag<80[2329]
YGR145W ENP2 "Essential nucleolar protein of unknown function; contains WD repeats, interacts with Mpp10p and Bfr2p, and has homology to Spb1p" Verified chr7:781772-783895 781772-783895 98.5% 206.54 92.27 115.70 95.62 16.26 16.73 149.41 105.66 16.49 0.55 0.43 0.07 -2.68 -2.04 Covered[2330]
YGR146C Putative protein of unknown function; induced by iron homeostasis transcription factor Aft2p; multicopy suppressor of a temperature sensitive hsf1 mutant Uncharacterized chr7:784228-784863 784228-784863 98.7% 127.47 176.87 125.88 92.42 863.63 788.74 152.17 109.15 826.19 0.56 0.44 3.42 2.92 3.47 Frag>80[2331,2332,2333]
YGR146C-A Putative protein of unknown function Uncharacterized chr7:785281-785442 785281-785442 98.0% 12.60 37.81 12.60 25.20 25.20 25.20 25.20 18.90 25.20 0.09 0.08 0.10 0.42 NaN Matched[2333]
YGR147C NAT2 "N alpha-acetyl-transferase, transfers acetyl group from acetyl coenzyme A to the N-terminal methionine residues of proteins" Verified chr7:786059-786925 786059-786925 99.1% 276.96 285.10 269.98 231.57 300.23 154.77 281.03 250.78 227.50 1.04 1.02 0.94 -0.14 -0.51 Matched[2335]
YGR148C RPL24B "Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Ap and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate" Verified chr7:787317-788184 787317-787791,788183-788184 63.9% 8782.73 7474.17 7621.75 6457.50 2902.43 2630.23 8128.45 7039.63 2766.33 30.01 28.58 11.46 -1.35 -2.40 Matched[2336]
YGR149W Putative protein of unknown function; predicted to be an integal membrane protein Uncharacterized chr7:789036-790334 789036-790334 99.2% 92.35 146.68 113.31 124.17 216.52 149.78 119.51 118.74 183.15 0.44 0.48 0.76 0.63 0.97 Matched[2337]
YGR150C "Protein of unknown function, contains PPR motifs; mutant has growth defects on both non-fermentable carbon sources and rich medium; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr7:790464-793058 790464-793058 99.3% 113.32 120.30 110.60 107.88 79.94 56.66 116.81 109.24 68.30 0.43 0.44 0.28 -0.68 -0.62 Matched[2338]
YGR151C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps almost completely with the verified ORF RSR1/BUD1/YGR152C" Dubious chr7:794660-794995 794660-794995 99.1% 348.35 231.23 333.33 228.23 162.16 81.08 289.79 280.78 121.62 1.07 1.14 0.50 -1.21 -0.92 Matched[2339]
YGR152C RSR1 "GTP-binding protein of the ras superfamily required for bud site selection, morphological changes in response to mating pheromone, and efficient cell fusion; localized to the plasma membrane; significantly similar to mammalian Rap GTPases" Verified chr7:794679-795497 794679-795497 99.4% 271.50 192.87 264.13 216.22 114.25 71.25 232.19 240.17 92.75 0.86 0.97 0.38 -1.37 -1.19 Matched[2339]
YGR153W Putative protein of unknown function Uncharacterized chr7:796097-796750 796097-796750 98.1% 28.04 32.72 43.62 34.27 65.43 71.67 30.38 38.95 68.55 0.11 0.16 0.28 0.82 0.23 Covered/w/another[2340]
YGR154C GTO1 Omega-class glutathione transferase; induced under oxidative stress; putative peroxisomal localization Verified chr7:796803-797873 796803-797873 99.2% 53.66 69.66 55.54 40.48 67.78 31.06 61.66 48.01 49.42 0.23 0.19 0.20 0.04 0.47 Matched[2340]
YGR155W CYS4 "Cystathionine beta-synthase, catalyzes the synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis" Verified chr7:798548-800071 798548-800071 98.9% 1252.86 1144.09 1079.09 981.60 453.66 368.10 1198.47 1030.34 410.88 4.42 4.18 1.70 -1.33 -0.80 Matched[2341]
YGR156W PTI1 Pta1p Interacting protein Verified chr7:800551-801828 800551-801828 99.1% 144.55 107.42 110.58 94.78 77.41 49.76 125.98 102.68 63.58 0.47 0.42 0.26 -0.69 0.04 Matched[2342]
YGR157W CHO2 "Phosphatidylethanolamine methyltransferase (PEMT), catalyzes the first step in the conversion of phosphatidylethanolamine to phosphatidylcholine during the methylation pathway of phosphatidylcholine biosynthesis" Verified chr7:802445-805054 802445-805054 99.1% 376.27 297.00 398.32 336.83 275.73 265.29 336.64 367.57 270.51 1.24 1.49 1.12 -0.44 0.24 Matched[2343]
YGR158C MTR3 "3'5' exoribonuclease, exosome subunit; nucleolar protein involved in export of mRNA and ribosomal subunits; homologous to the E. coli exonuclease RNase PH" Verified chr7:805274-806026 805274-806026 98.9% 283.27 210.77 189.29 142.31 25.51 18.80 247.02 165.80 22.15 0.91 0.67 0.09 -2.90 -2.41 Matched[2344]
YGR160W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr7:807078-807689 807078-807689 98.5% 1225.37 583.67 701.40 548.85 71.30 18.24 904.52 625.12 44.77 3.34 2.54 0.19 -3.80 -0.41 Matched[2346]
YGR159C NSR1 "Nucleolar protein that binds nuclear localization sequences, required for pre-rRNA processing and ribosome biogenesis" Verified chr7:806417-807661 806417-807661 98.7% 1465.82 673.09 822.84 631.58 80.58 18.72 1069.45 727.21 49.65 3.95 2.95 0.21 -3.87 -3.15 Frag>80[2345,2346,2347]
YGR161C RTS3 Putative component of the protein phosphatase type 2A complex Uncharacterized chr7:808634-809425 808634-809425 98.4% 87.29 335.04 136.07 119.38 1046.21 655.97 211.17 127.73 851.09 0.78 0.52 3.53 2.74 2.42 Frag>80[2347,2348,2349]
YGR161W-C Putative protein of unknown function; identified by sequence comparison with hemiascomycetous yeast species Uncharacterized chr7:810232-810510 810232-810510 98.1% 62.13 113.29 124.26 102.33 712.65 515.30 87.71 113.29 613.98 0.32 0.46 2.54 2.44 NaN Matched[2350]
YGR162W TIF4631 "Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); associates with the poly(A)-binding protein Pab1p, also interacts with eIF4A (Tif1p); homologous to Tif4632p" Verified chr7:824064-826922 824064-826922 98.4% 726.06 491.14 494.34 471.24 83.87 72.14 608.60 482.79 78.01 2.25 1.96 0.32 -2.63 -2.20 Covered/w/another[2352]
YGR163W GTR2 "Cytoplasmic GTP binding protein that negatively regulates Ran/Tc4 GTPase cycle; subunit of EGO complex, which is involved in microautophagy regulation, and of GSE complex, required for sorting of Gap1p; homolog of human RagC and RagD" Verified chr7:827557-828582 827557-828582 98.7% 196.54 188.64 166.91 159.01 233.09 133.33 192.59 162.96 183.21 0.71 0.66 0.76 0.17 0.29 Covered/w/another[2352]
YGR164W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr7:828630-828965 828630-828965 76.5% 15.55 3.89 15.55 3.89 19.44 7.78 9.72 9.72 13.61 0.04 0.04 0.06 0.49 0.18 Overlap[2352]
YGR165W MRPS35 Mitochondrial ribosomal protein of the small subunit Verified chr7:829121-830158 829121-830158 98.7% 251.92 239.23 238.25 271.45 240.21 177.71 245.58 254.85 208.96 0.91 1.03 0.87 -0.29 -0.14 Frag>80[2353,2354]
YGR166W KRE11 "Protein involved in biosynthesis of cell wall beta-glucans; subunit of the TRAPP (transport protein particle) complex, which is involved in the late steps of endoplasmic reticulum to Golgi transport" Verified chr7:830520-832202 830520-832202 99.1% 125.89 96.52 95.32 82.73 61.75 55.75 111.20 89.02 58.75 0.41 0.36 0.24 -0.60 -0.67 Matched[2355]
YGR167W CLC1 "Clathrin light chain, subunit of the major coat protein involved in intracellular protein transport and endocytosis; thought to regulate clathrin function, two Clathrin heavy chains (CHC1) form the clathrin triskelion structural component" Verified chr7:832461-833162 832461-833162 98.3% 1028.92 1137.61 1014.43 1140.51 1631.79 1305.72 1083.27 1077.47 1468.75 4.00 4.37 6.09 0.45 0.67 Matched[2356]
YGR168C Putative protein of unknown function; YGR168C is not an essential gene Uncharacterized chr7:833357-834487 833357-834487 99.1% 105.24 105.24 99.88 74.91 150.72 74.02 105.24 87.40 112.37 0.39 0.35 0.47 0.36 0.08 Frag<80[2357]
YGR169C PUS6 Pseudouridine synthase responsible for modification of cytoplasmic and mitochondrial tRNAs at position 31; mutation of Asp168 to Ala abolishes enzyme activity; not essential for viability Verified chr7:834694-835908 834694-835908 99.3% 81.26 84.58 69.65 68.82 63.85 41.46 82.92 69.24 52.66 0.31 0.28 0.22 -0.40 -0.25 Covered[2358]
YGR169C-A Putative protein of unknown function Uncharacterized chr7:836392-836670 836392-836670 99.6% 604.77 597.57 633.57 428.38 885.56 565.17 601.17 530.97 725.36 2.22 2.16 3.01 0.45 NaN Matched[2360]
YGR170W PSD2 "Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes, converts phosphatidylserine to phosphatidylethanolamine" Verified chr7:837147-840563 837147-840563 98.8% 132.16 172.16 133.05 136.01 120.60 146.09 152.16 134.53 133.34 0.56 0.55 0.55 -0.01 0.43 Matched[2361]
YGR171C MSM1 "Mitochondrial methionyl-tRNA synthetase (MetRS), functions as a monomer in mitochondrial protein synthesis; functions similarly to cytoplasmic MetRS although the cytoplasmic form contains a zinc-binding domain not found in Msm1p" Verified chr7:840829-842556 840829-842556 99.1% 79.38 89.89 81.13 77.63 71.79 56.62 84.63 79.38 64.20 0.31 0.32 0.27 -0.31 0.03 Matched[2362]
YGR172C YIP1 "Integral membrane protein required for the biogenesis of ER-derived COPII transport vesicles; interacts with Yif1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles" Verified chr7:842850-843596 842850-843596 98.7% 360.70 364.77 336.29 290.19 172.21 108.48 362.73 313.24 140.35 1.34 1.27 0.58 -1.16 -1.08 Frag>80[2363,2364]
YGR173W RBG2 Protein with similarity to mammalian developmentally regulated GTP-binding protein Uncharacterized chr7:843859-844965 843859-844965 98.5% 260.36 184.27 197.10 164.10 33.92 21.09 222.32 180.60 27.50 0.82 0.73 0.11 -2.72 -2.24 Matched[2365]
YGR174C CBP4 Mitochondrial protein required for assembly of ubiquinol cytochrome-c reductase complex (cytochrome bc1 complex); interacts with Cbp3p and function is partially redundant with that of Cbp3p Verified chr7:845898-846410 845898-846410 99.3% 235.54 268.91 255.17 263.02 885.25 453.42 252.23 259.10 669.34 0.93 1.05 2.77 1.37 0.83 Matched[2366]
YGR174W-A Putative protein of unknown function Uncharacterized chr7:846660-846746 846660-846746 99.0% 69.67 92.89 34.83 116.11 603.77 359.94 81.28 75.47 481.86 0.30 0.31 2.00 2.67 NaN Matched[2367]
YGR175C ERG1 "Squalene epoxidase, catalyzes the epoxidation of squalene to 2,3-oxidosqualene; plays an essential role in the ergosterol-biosynthesis pathway and is the specific target of the antifungal drug terbinafine" Verified chr7:846938-848428 846938-848428 99.0% 1072.27 1602.98 904.18 908.24 469.71 441.92 1337.63 906.21 455.82 4.94 3.68 1.89 -0.99 -0.83 Matched[2368]
YGR176W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr7:848725-849072 848725-849072 98.5% 67.09 116.67 61.25 26.25 14.58 20.42 91.88 43.75 17.50 0.34 0.18 0.07 -1.32 0.11 Covered/w/another[2369]
YGR177C ATF2 "Alcohol acetyltransferase, may play a role in steroid detoxification; forms volatile esters during fermentation, which is important in brewing" Verified chr7:848834-850441 848834-850441 99.0% 56.56 99.92 39.59 23.88 13.83 13.83 78.24 31.74 13.83 0.29 0.13 0.06 -1.20 -1.41 Matched[2369]
YGR178C PBP1 Protein interacting with poly(A)-binding protein Pab1p; likely involved in controlling the extent of mRNA polyadenylation; forms a complex with Mkt1p that may regulate HO translation; interacts with Lsm12p in a copurification assay Verified chr7:851052-853220 851052-853220 99.1% 432.88 420.77 431.48 412.86 515.73 558.55 426.83 422.17 537.14 1.58 1.71 2.23 0.35 1.03 Frag>80[2370,2371]
YGR179C OKP1 "Outer kinetochore protein, required for accurate mitotic chromosome segregation; component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p) that functions as a platform for kinetochore assembly" Verified chr7:853680-854900 853680-854900 99.2% 91.61 84.18 75.10 85.83 78.40 54.47 87.90 80.47 66.44 0.32 0.33 0.28 -0.28 0.17 Matched[2372]
YGR180C RNR4 "Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits" Verified chr7:855269-856306 855269-856306 98.9% 2451.94 3316.36 2414.91 2495.80 1710.32 1786.33 2884.15 2455.35 1748.33 10.65 9.97 7.24 -0.49 0.11 Frag>80[2373,2374]
YGR181W TIM13 "Mitochondrial intermembrane space protein, forms a complex with TIm8p that mediates import and insertion of a subset of polytopic inner membrane proteins; may prevent aggregation of incoming proteins in a chaperone-like manner" Verified chr7:858292-858609 858292-858609 98.8% 525.41 560.44 598.65 531.78 439.43 318.43 542.92 565.21 378.93 2.00 2.29 1.57 -0.58 -0.42 Matched[2375]
YGR182C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF TIM13/YGR181W" Dubious chr7:858556-858909 858556-858909 99.2% 757.21 742.97 853.99 828.37 1423.32 680.35 750.09 841.18 1051.83 2.77 3.41 4.36 0.32 -2.09 Frag>80[2375,2376]
YGR183C QCR9 "Subunit 9 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; required for electron transfer at the ubiquinol oxidase site of the complex" Verified chr7:859068-859481 859068-859265,859479-859481 99.1% 627.48 898.56 858.40 953.78 2309.14 1295.13 763.02 906.09 1802.13 2.82 3.68 7.47 0.99 0.14 Frag>80[2376,2377]
YGR184C UBR1 "Ubiquitin-protein ligase (E3) that interacts with Rad6p/Ubc2p to ubiquitinate substrates of the N-end rule pathway; binds to the Rpn2p, Rpt1p, and Rpt6p proteins of the 19S particle of the 26S proteasome" Verified chr7:859906-865758 859906-865758 99.2% 111.08 107.98 102.30 90.42 73.54 97.13 109.53 96.36 85.34 0.40 0.39 0.35 -0.18 0.41 Frag>80[2377,2378,2379]
YGR185C TYS1 "Cytoplasmic tyrosyl-tRNA synthetase, class I aminoacyl-tRNA synthetase that aminoacylates tRNA(Tyr), required for cytoplasmic protein synthesis, interacts with positions 34 and 35 of the anticodon of tRNATyr" Verified chr7:866341-867525 866341-867525 99.0% 1065.64 902.81 934.36 908.78 614.66 601.88 984.23 921.57 608.27 3.63 3.74 2.52 -0.60 -0.29 Matched[2380]
YGR186W TFG1 TFIIF (Transcription Factor II) largest subunit; involved in both transcription initiation and elongation of RNA polymerase II; homologous to human RAP74 Verified chr7:867779-869986 867779-869986 98.2% 344.18 408.31 353.41 375.09 405.54 386.17 376.25 364.25 395.86 1.39 1.48 1.64 0.12 0.82 Matched[2381]
YGR187C HGH1 Protein of unknown function with similarity to human HMG1 and HMG2; localizes to the cytoplasm Verified chr7:870237-871421 870237-871421 99.3% 259.27 147.91 158.11 124.96 30.60 12.75 203.59 141.54 21.68 0.75 0.57 0.09 -2.71 -2.95 Matched[2382]
YGR188C BUB1 "Protein kinase that forms a complex with Mad1p and Bub3p that is crucial in the checkpoint mechanism required to prevent cell cycle progression into anaphase in the presence of spindle damage, associates with centromere DNA via Skp1p" Verified chr7:872049-875114 872049-875114 99.3% 40.74 28.25 26.28 12.48 20.04 39.75 34.50 19.38 29.90 0.13 0.08 0.12 0.63 0.91 Frag>80[2383,2384,2385]
YGR189C CRH1 "Cell wall protein that functions in the transfer of chitin to beta(1-6)glucan, putative chitin transglycosidase" Verified chr7:876674-878197 876674-878197 97.4% 866.72 780.45 818.87 677.34 533.78 386.86 823.59 748.10 460.32 3.04 3.04 1.91 -0.70 -0.22 Frag>80[2386,2387]
YGR191W HIP1 "High-affinity histidine permease, also involved in the transport of manganese ions" Verified chr7:880425-882236 880425-882236 98.9% 278.03 249.56 239.51 197.08 94.35 92.68 263.79 218.29 93.51 0.97 0.89 0.39 -1.22 -0.66 Frag>80[2388,2389]
YGR190C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene HIP1/YGR191W" Dubious chr7:880301-880666 880301-880666 99.2% 146.04 157.06 129.51 132.26 38.58 77.15 151.55 130.88 57.86 0.56 0.53 0.24 -1.18 -0.25 Covered/w/another[2388]
YGR192C TDH3 "Glyceraldehyde-3-phosphate dehydrogenase, isozyme 3, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall" Verified chr7:882817-883815 882817-883815 30.2% 74272.28 73532.55 71479.19 65607.74 83553.83 62283.89 73902.41 68543.47 72918.86 272.81 278.23 302.13 0.09 -2.26 Frag>80[2390,2391,2392]
YGR193C PDX1 "Dihydrolipoamide dehydrogenase (E3)-binding protein (E3BP) of the mitochondrial pyruvate dehydrogenase (PDH) complex, plays a structural role in the complex by binding and positioning E3 to the dihydrolipoamide acetyltransferase (E2) core" Verified chr7:884514-885746 884514-885746 99.1% 319.07 322.35 344.43 309.26 346.89 307.62 320.71 326.85 327.25 1.18 1.33 1.36 0.00 0.73 Matched[2393]
YGR194C XKS1 "Xylulokinase, converts D-xylulose and ATP to xylulose 5-phosphate and ADP; rate limiting step in fermentation of xylulose; required for xylose fermentation by recombinant S. cerevisiae strains" Verified chr7:886078-887880 886078-887880 99.0% 107.00 183.74 165.26 191.03 633.02 484.01 145.37 178.14 558.52 0.54 0.72 2.31 1.65 1.82 Frag>80[2394,2395,2396]
YGR195W SKI6 3'-to-5' phosphorolytic exoribonuclease that is a subunit of the exosome; required for 3' processing of the 5.8S rRNA; involved in 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs Verified chr7:888887-889627 888887-889627 98.5% 261.63 212.32 226.01 171.22 106.84 86.30 236.97 198.62 96.57 0.87 0.81 0.40 -1.04 -0.50 Covered/w/another[2397]
YGR196C FYV8 "Protein of unknown function, required for survival upon exposure to K1 killer toxin" Verified chr7:889738-892191 889738-892191 99.4% 111.14 117.29 94.74 90.23 103.76 91.46 114.22 92.48 97.61 0.42 0.38 0.40 0.08 0.22 Covered/w/another[2397]
YGR197C SNG1 Protein involved in nitrosoguanidine (MNNG) resistance; expression is regulated by transcription factors involved in multidrug resistance Verified chr7:892502-894145 892502-894145 98.9% 54.12 63.96 39.36 35.05 69.49 62.11 59.04 37.21 65.80 0.22 0.15 0.27 0.82 1.17 Covered/w/another[2398]
YGR198W YPP1 "Cargo-transport protein involved in endocytosis; may interact with ribosomes, based on co-purification experiments; GFP-fusion protein localizes to the cytoplasm; YGR198W is an essential gene" Verified chr7:894698-897151 894698-897151 98.9% 129.73 147.03 107.49 102.55 139.20 130.14 138.38 105.02 134.67 0.51 0.43 0.56 0.36 0.40 Covered/w/another[2398]
YGR199W PMT6 "Protein O-mannosyltransferase, transfers mannose from dolichyl phosphate-D-mannose to protein serine/threonine residues of secretory proteins; reaction is essential for cell wall rigidity; member of a family of mannosyltransferases" Verified chr7:897507-899786 897507-899786 98.9% 192.85 192.40 165.36 151.17 163.14 133.00 192.63 158.27 148.07 0.71 0.64 0.61 -0.10 0.17 Frag>80[2399,2400]
YGR200C ELP2 "Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; target of Kluyveromyces lactis zymocin" Verified chr7:899909-902275 899909-902275 99.2% 225.34 147.81 167.41 115.86 19.59 7.67 186.57 141.64 13.63 0.69 0.57 0.06 -3.38 -2.59 Matched[2401]
YGR201C Putative protein of unknown function Uncharacterized chr7:902525-903202 902525-903202 98.9% 85.02 129.77 108.89 73.09 310.25 214.79 107.40 90.99 262.52 0.40 0.37 1.09 1.53 1.71 Matched[2402]
YGR202C PCT1 "Cholinephosphate cytidylyltransferase, also known as CTP:phosphocholine cytidylyltransferase, rate-determining enzyme of the CDP-choline pathway for phosphatidylcholine synthesis, inhibited by Sec14p, activated upon lipid-binding" Verified chr7:903479-904753 903479-904753 99.1% 261.21 356.98 288.91 282.58 210.55 201.84 309.09 285.74 206.19 1.14 1.16 0.85 -0.47 0.19 Matched[2403]
YGR203W Putative protein with sequence similarity to protein tyrosine phosphatases of the CDC25-like phosphatase family; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus Uncharacterized chr7:905242-905688 905242-905688 97.9% 182.72 166.73 173.58 116.48 223.83 91.36 174.72 145.03 157.59 0.64 0.59 0.65 0.12 0.23 Covered/w/another[2404]
YGR204W ADE3 "Cytoplasmic trifunctional enzyme C1-tetrahydrofolate synthase, involved in single carbon metabolism and required for biosynthesis of purines, thymidylate, methionine, and histidine" Verified chr7:905939-908779 905939-908779 98.4% 1082.05 1133.91 1197.94 1020.88 382.38 463.94 1107.98 1109.41 423.16 4.09 4.50 1.75 -1.39 -0.77 Covered/w/another[2404]
YGR204C-A "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr7:909066-909179 909066-909179 98.5% 160.36 213.81 160.36 213.81 276.17 169.27 187.08 187.08 222.72 0.69 0.76 0.92 0.25 NaN Covered/w/another[2405]
YGR205W ATP-binding protein of unknown function; crystal structure resembles that of E.coli pantothenate kinase and other small kinases Verified chr7:909218-910090 909218-910090 98.7% 219.28 331.82 258.73 287.73 565.02 384.03 275.55 273.23 474.52 1.02 1.11 1.97 0.80 0.74 Matched[2405]
YGR206W MVB12 ESCRT-I subunit necessary for the efficient transport of cargo proteins to the vacuolar lumen; deletion mutant sensitive to rapamycin and nystatin; green fluorescent protein (GFP)-fusion protein localizes to endosome Verified chr7:910437-910742 910437-910742 99.0% 188.07 194.67 194.67 171.57 428.92 227.66 191.37 183.12 328.29 0.71 0.74 1.36 0.84 0.40 Matched[2406]
YGR207C "Protein that interacts with frataxin (Yfh1p); putative homolog of mammalian electron transfer flavoprotein complex subunit ETF-beta; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr7:910848-911633 910848-911633 99.3% 514.97 439.39 570.06 538.03 555.96 399.68 477.18 554.04 477.82 1.76 2.25 1.98 -0.21 -0.16 Matched[2407]
YGR208W SER2 "Phosphoserine phosphatase of the phosphoglycerate pathway, involved in serine and glycine biosynthesis, expression is regulated by the available nitrogen source" Verified chr7:911888-912817 911888-912817 98.6% 650.24 490.95 564.05 447.31 268.39 150.56 570.60 505.68 209.47 2.11 2.05 0.87 -1.27 -1.05 Matched[2408]
YGR209C TRX2 "Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance" Verified chr7:912918-913232 912918-913232 97.8% 4918.75 3001.22 4814.92 3247.80 9636.34 4947.95 3959.98 4031.36 7292.15 14.62 16.36 30.21 0.86 -0.66 Matched[2409]
YGR210C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr7:913508-914743 913508-914743 99.2% 304.31 255.36 289.63 229.26 770.17 770.98 279.84 259.44 770.57 1.03 1.05 3.19 1.57 2.01 Matched[2410]
YGR211W ZPR1 "Essential protein with two zinc fingers, present in the nucleus of growing cells but relocates to the cytoplasm in starved cells via a process mediated by Cpr1p; binds to translation elongation factor eEF-1 (Tef1p)" Verified chr7:915246-916706 915246-916706 98.5% 327.22 175.07 211.89 204.94 2052.22 5665.49 251.14 208.42 3858.85 0.93 0.85 15.99 4.21 3.72 Matched[2411]
YGR212W SLI1 "N-acetyltransferase, confers resistance to the sphingolipid biosynthesis inhibitor myriocin (ISP-1) by converting it into N-acetyl-myriocin, co-operates with Ypk1p in mediating resistance to myriocin" Verified chr7:917045-918451 917045-918451 99.1% 35.16 40.90 39.46 33.01 38.75 25.11 38.03 36.23 31.93 0.14 0.15 0.13 -0.18 0.35
YGR213C RTA1 Protein involved in 7-aminocholesterol resistance; has seven potential membrane-spanning regions Verified chr7:918517-919470 918517-919470 99.0% 48.72 60.37 23.30 27.54 31.77 16.94 54.54 25.42 24.36 0.20 0.10 0.10 -0.06 1.50
YGR214W RPS0A "Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Bp; required for maturation of 18S rRNA along with Rps0Bp; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal" Verified chr7:920580-921793 920580-920669,921125-921793 79.4% 7495.23 5720.53 6563.10 5869.80 1620.46 1658.60 6607.88 6216.45 1639.53 24.39 25.23 6.79 -1.92 -2.31 Matched[2412]
YGR215W RSM27 Mitochondrial ribosomal protein of the small subunit Verified chr7:922180-922512 922180-922512 98.3% 412.21 406.11 406.11 357.25 500.76 332.82 409.16 381.68 416.79 1.51 1.55 1.73 0.13 -0.58 Matched[2413]
YGR216C GPI1 "Membrane protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; human and mouse GPI1p are functional homologs" Verified chr7:922638-924467 922638-924467 99.0% 108.14 116.41 89.93 86.07 72.83 44.69 112.28 88.00 58.76 0.41 0.36 0.24 -0.58 -0.33 Matched[2414]
YGR217W CCH1 "Voltage-gated high-affinity calcium channel involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones; interacts and co-localizes with Mid1p, suggesting Cch1p and Mid1p function together" Verified chr7:924699-930818 924699-930818 98.9% 39.82 35.69 31.23 25.12 15.37 20.16 37.76 28.17 17.76 0.14 0.11 0.07 -0.67 -0.38 Frag<80[2415,2416]
YGR218W CRM1 "Major karyopherin, involved in export of proteins, RNAs, and ribosomal subunits from the nucleus" Verified chr7:932544-935798 932544-935798 99.0% 338.83 313.08 334.18 327.35 306.56 314.94 325.96 330.76 310.75 1.20 1.34 1.29 -0.09 0.32 Covered/w/another[2418]
YGR219W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF MRPL9/YGR220C" Dubious chr7:936038-936379 936038-936379 99.5% 367.20 343.70 323.13 337.82 434.76 317.26 355.45 330.48 376.01 1.31 1.34 1.56 0.19 0.03 Covered/w/another[2418]
YGR220C MRPL9 Mitochondrial ribosomal protein of the large subunit Verified chr7:936077-936886 936077-936886 99.2% 304.79 271.20 338.38 322.21 370.72 294.84 288.00 330.29 332.78 1.06 1.34 1.38 0.01 0.21 Covered/w/another[2418]
YGR221C TOS2 Protein involved in localization of Cdc24p to the site of bud growth; may act as a membrane anchor; localizes to the bud neck and bud tip; potentially phosphorylated by Cdc28p Verified chr7:937127-938995 937127-938995 98.8% 122.43 101.84 105.09 75.30 48.21 21.13 112.13 90.20 34.67 0.41 0.37 0.14 -1.38 -2.32 Matched[2419]
YGR222W PET54 "Mitochondrial translational activator specific for the COX3 mRNA, acts together with Pet122p and Pet494p; also required for splicing of the COX1 intron AI5 beta; located in the mitochondrial inner membrane" Verified chr7:939926-940807 939926-940807 98.9% 358.93 386.45 300.44 266.04 329.11 121.55 372.69 283.24 225.33 1.38 1.15 0.93 -0.33 -0.27 Matched[2420]
YGR223C HSV2 "Phosphatidylinositol 3,5-bisphosphate-binding protein, predicted to fold as a seven-bladed beta-propeller; displays punctate cytoplasmic localization" Verified chr7:940872-942218 940872-942218 99.1% 106.35 144.54 135.56 132.56 218.69 164.01 125.44 134.06 191.35 0.46 0.54 0.79 0.51 0.35 Matched[2421]
YGR224W AZR1 "Plasma membrane transporter of the major facilitator superfamily, involved in resistance to azole drugs such as ketoconazole and fluconazole" Verified chr7:942809-944650 942809-944650 98.9% 62.05 84.56 54.91 47.77 54.36 47.22 73.30 51.34 50.79 0.27 0.21 0.21 -0.02 -0.17 Covered/w/another[2422]
YGR225W AMA1 Activator of meiotic anaphase promoting complex (APC/C); Cdc20p family member; required for initiation of spore wall assembly; required for Clb1p degradation during meiosis Verified chr7:945148-947022 945148-946330,946424-947022 98.8% 16.47 23.28 12.49 12.49 88.60 61.34 19.88 12.49 74.97 0.07 0.05 0.31 2.58 2.71 Covered/w/another[2422]
YGR226C "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; overlaps significantly with a verified ORF, AMA1/YGR225W" Dubious chr7:946795-947004 946795-947004 98.6% 24.15 67.63 24.15 24.15 164.25 86.96 45.89 24.15 125.60 0.17 0.10 0.52 2.38 0.69 Covered/w/another[2422]
YGR227W DIE2 "Dolichyl-phosphoglucose-dependent alpha-1,2 glucosyltransferase of the ER, functions in the pathway that synthesizes the dolichol-linked oligosaccharide precursor for N-linked protein glycosylation, has a role in regulation of ITR1 and INO1" Verified chr7:947423-949000 947423-949000 99.3% 188.96 157.68 184.49 135.34 109.80 106.61 173.32 159.91 108.21 0.64 0.65 0.45 -0.56 -0.02 Matched[2423]
YGR228W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF SMI1/YGR229C" Dubious chr7:949368-949712 949368-949712 99.9% 972.31 943.28 937.48 809.77 644.33 487.60 957.79 873.62 565.97 3.54 3.55 2.35 -0.63 -0.19 Covered/w/another[2424]
YGR229C SMI1 Protein involved in the regulation of cell wall synthesis; proposed to be involved in coordinating cell cycle progression with cell wall integrity Verified chr7:949385-950902 949385-950902 99.2% 651.90 582.86 610.74 586.84 404.28 308.69 617.38 598.79 356.48 2.28 2.43 1.48 -0.75 -0.67 Matched[2424]
YGR230W BNS1 "Protein with some similarity to Spo12p; overexpression bypasses need for Spo12p, but not required for meiosis" Verified chr7:951897-952310 951897-952310 98.8% 92.91 58.68 122.25 100.24 286.06 136.92 75.79 111.25 211.49 0.28 0.45 0.88 0.93 0.11 Matched[2425]
YGR231C PHB2 "Subunit of the prohibitin complex (Phb1p-Phb2p), a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation" Verified chr7:952551-953483 952551-953483 99.1% 752.47 721.11 794.63 726.52 1131.94 904.91 736.79 760.57 1018.42 2.72 3.09 4.22 0.42 0.47 Frag>80[2426,2427]
YGR232W NAS6 "Regulatory, non-ATPase subunit of the 26S proteasome; homolog of the human oncoprotein gankyrin, which interacts with the retinoblastoma tumor suppressor (Rb) and cyclin-dependent kinase 4/6" Verified chr7:953963-954649 953963-954649 98.6% 252.45 295.26 252.45 255.40 472.41 307.07 273.85 253.92 389.74 1.01 1.03 1.61 0.62 0.31 Matched[2428]
YGR233C PHO81 "Cyclin-dependent kinase (CDK) inhibitor, regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels; inhibitory activity for Pho80p-Pho85p requires myo-D-inositol heptakisphosphate (IP7) generated by Vip1p" Verified chr7:954677-958213 954677-958213 98.5% 184.78 165.27 173.59 171.87 81.77 73.45 175.02 172.73 77.61 0.65 0.70 0.32 -1.15 -0.47 Matched[2429]
YGR234W YHB1 "Nitric oxide oxidoreductase, flavohemoglobin involved in nitric oxide detoxification; plays a role in the oxidative and nitrosative stress responses" Verified chr7:959908-961107 959908-961107 98.9% 1807.12 985.32 1524.76 1426.14 306.81 191.33 1396.22 1475.45 249.07 5.15 5.99 1.03 -2.57 -1.77 Matched[2430]
YGR235C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr7:961364-962065 961364-962065 99.0% 281.91 299.17 330.82 314.99 523.55 316.43 290.54 322.91 419.99 1.07 1.31 1.74 0.38 -0.63 Matched[2431]
YGR236C SPG1 "Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr7:962534-962821 962534-962821 99.5% 0.00 17.45 6.98 3.49 97.75 41.89 8.73 5.24 69.82 0.03 0.02 0.29 3.74 2.16 Matched[2432]
YGR237C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr7:963303-965660 963303-965660 99.1% 110.82 144.19 124.08 124.08 230.20 216.08 127.51 124.08 223.14 0.47 0.50 0.92 0.85 1.31 Matched[2433]
YGR238C KEL2 "Protein that functions in a complex with Kel1p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate" Verified chr7:966044-968692 966044-968692 99.1% 75.06 93.34 91.06 78.10 130.30 113.16 84.20 84.58 121.73 0.31 0.34 0.50 0.53 1.02 Matched[2434]
YGR239C PEX21 Peroxin required for targeting of peroxisomal matrix proteins containing PTS2; interacts with Pex7p; partially redundant with Pex18p Verified chr7:969192-970058 969192-970058 98.6% 79.52 105.25 60.81 46.78 84.20 37.42 92.39 53.80 60.81 0.34 0.22 0.25 0.18 -0.55 Frag>80[2435,2436]
YGR240C PFK1 "Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes" Verified chr7:970776-973739 970776-973739 98.8% 1559.91 1358.77 1412.05 1356.73 580.53 761.51 1459.34 1384.39 671.02 5.39 5.62 2.78 -1.04 -0.55 Frag>80[2437,2438,2439]
YGR240C-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr7:974582-974782 974582-974782 98.8% 75.55 161.18 120.88 65.48 80.59 75.55 118.36 93.18 78.07 0.44 0.38 0.32 -0.26 NaN Matched[2440]
YGR242W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YAP1802/YGR241C" Dubious chr7:976420-976728 976420-976728 98.8% 91.72 94.99 140.85 121.20 114.64 153.95 93.35 131.02 134.30 0.34 0.53 0.56 0.04 0.49 Covered/w/another[2441]
YGR241C YAP1802 "Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1801p, member of the AP180 protein family" Verified chr7:974880-976586 974880-976586 98.9% 181.28 189.58 201.43 190.76 252.38 229.86 185.43 196.09 241.12 0.68 0.80 1.00 0.30 0.86 Matched[2441]
YGR243W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr7:977341-977781 977341-977781 98.7% 55.15 103.41 133.28 135.58 519.34 312.52 79.28 134.43 415.93 0.29 0.55 1.72 1.63 1.28 Matched[2442]
YGR244C LSC2 "Beta subunit of succinyl-CoA ligase, which is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate" Verified chr7:978041-979324 978041-979324 99.2% 915.05 1126.94 1018.64 1192.86 1387.48 1250.93 1020.99 1105.75 1319.21 3.77 4.49 5.47 0.25 0.43 Matched[2443]
YGR245C SDA1 "Highly conserved nuclear protein required for actin cytoskeleton organization and passage through Start, plays a critical role in G1 events, binds Nap1p, also involved in 60S ribosome biogenesis" Verified chr7:979770-982073 979770-982073 99.3% 287.73 100.58 170.54 129.00 19.68 7.00 194.15 149.77 13.34 0.72 0.61 0.06 -3.49 -0.66 Matched[2444]
YGR246C BRF1 "TFIIIB B-related factor, one of three subunits of RNA polymerase III transcription initiation factor TFIIIB, binds TFIIIC and TBP and recruits RNA pol III to promoters, amino-terminal half is homologous to TFIIB" Verified chr7:982487-984277 982487-984277 99.2% 133.38 144.64 121.56 103.55 117.62 79.35 139.01 112.56 98.49 0.51 0.46 0.41 -0.19 0.07 Matched[2445]
YGR247W CPD1 "Cyclic nucleotide phosphodiesterase, hydrolyzes ADP-ribose 1'', 2''-cyclic phosphate to ADP-ribose 1''-phosphate; may have a role in tRNA splicing; no detectable phenotype is conferred by null mutation or by overexpression" Verified chr7:984971-985690 984971-985690 98.4% 111.48 107.25 129.83 80.44 166.52 115.72 109.37 105.13 141.12 0.40 0.43 0.58 0.42 0.46 Matched[2446]
YGR248W SOL4 6-phosphogluconolactonase with similarity to Sol3p Verified chr7:985977-986744 985977-986744 98.5% 35.68 169.14 113.64 154.61 5104.72 4314.50 102.41 134.13 4709.61 0.38 0.54 19.51 5.13 3.98 Matched[2447]
YGR249W MGA1 Protein similar to heat shock transcription factor; multicopy suppressor of pseudohyphal growth defects of ammonium permease mutants Verified chr7:988054-989424 988054-989424 99.0% 7.37 12.52 7.37 6.63 58.93 64.09 9.95 7.00 61.51 0.04 0.03 0.25 3.14 3.02 Covered[2448]
YGR250C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr7:991181-993526 991181-993526 99.2% 110.89 143.12 132.38 109.60 1465.59 1509.00 127.00 120.99 1487.29 0.47 0.49 6.16 3.62 3.30 Matched[2450]
YGR251W Putative protein of unknown function; deletion mutant has defects in pre-rRNA processing; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the nucleolus; YGR251W is an essential gene Uncharacterized chr7:995644-996234 995644-996234 98.1% 136.26 124.18 103.49 43.12 27.60 13.80 130.22 73.30 20.70 0.48 0.30 0.09 -1.82 -1.98 Matched[2451]
YGR252W GCN5 "Histone acetyltransferase, acetylates N-terminal lysines on histones H2B and H3; catalytic subunit of the ADA and SAGA histone acetyltransferase complexes; founding member of the Gcn5p-related N-acetyltransferase superfamily" Verified chr7:996874-998193 996874-998193 98.5% 152.98 158.36 136.84 140.68 141.45 96.86 155.67 138.76 119.15 0.57 0.56 0.49 -0.22 0.01 Matched[2452]
YGR253C PUP2 Alpha subunit of the 20S proteasome involved in ubiquitin-dependent catabolism; human homolog is subunit zeta Verified chr7:998363-999145 998363-999145 99.2% 1021.25 927.24 1000.64 950.42 2029.62 1415.33 974.24 975.53 1722.47 3.60 3.96 7.14 0.82 0.40 Frag>80[2453,2454]
YGR254W ENO1 "Enolase I, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; expression is repressed in response to glucose" Verified chr7:1000932-1002245 1000932-1002245 41.3% 8599.22 15441.34 9065.68 9607.74 9213.18 8051.62 12020.28 9336.71 8632.40 44.37 37.90 35.77 -0.11 -0.34 Matched[2456]
YGR255C COQ6 "Putative flavin-dependent monooxygenase, involved in ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes" Verified chr7:1002528-1003967 1002528-1003967 98.9% 279.37 424.67 331.32 315.87 735.63 671.05 352.02 323.59 703.34 1.30 1.31 2.91 1.12 1.36 Matched[2457]
YGR256W GND2 "6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone" Verified chr7:1004630-1006108 1004630-1006108 98.3% 13.07 27.53 17.89 14.45 753.53 754.90 20.30 16.17 754.21 0.07 0.07 3.12 5.54 3.40 Matched[2458]
YGR257C MTM1 "Mitochondrial protein of the mitochondrial carrier family, involved in activating mitochondrial Sod2p probably by facilitating insertion of an essential manganese cofactor" Verified chr7:1006211-1007311 1006211-1007311 99.1% 231.06 217.31 229.23 198.05 207.22 116.45 224.18 213.64 161.83 0.83 0.87 0.67 -0.40 0.18 Matched[2459]
YGR258C RAD2 "Single-stranded DNA endonuclease, cleaves single-stranded DNA during nucleotide excision repair to excise damaged DNA; subunit of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPG protein" Verified chr7:1007677-1010772 1007677-1010772 99.3% 81.01 87.51 78.73 89.14 120.37 118.42 84.26 83.93 119.39 0.31 0.34 0.49 0.51 1.01 Matched[2460]
YGR260W TNA1 "High affinity nicotinic acid plasma membrane permease, responsible for uptake of low levels of nicotinic acid; expression of the gene increases in the absence of extracellular nicotinic acid or para-aminobenzoate (PABA)" Verified chr7:1012491-1014095 1012491-1014095 98.8% 481.77 498.16 515.82 495.01 417.45 402.94 489.96 505.41 410.19 1.81 2.05 1.70 -0.30 0.11 Matched[2462]
YGR259C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps almost completely with the verified ORF TNA1/YGR260W" Dubious chr7:1012487-1012927 1012487-1012927 98.6% 303.65 317.45 365.76 292.15 223.14 243.84 310.55 328.96 233.49 1.15 1.34 0.97 -0.49 -0.04 Covered/w/another[2462]
YGR261C APL6 Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline phosphatase to the vacuole via the alternate pathway; exists in both cytosolic and peripherally associated membrane-bound pools Verified chr7:1014327-1016756 1014327-1016756 99.2% 250.67 233.24 183.43 215.80 163.51 163.93 241.95 199.62 163.72 0.89 0.81 0.68 -0.29 0.07 Matched[2463]
YGR262C BUD32 "Protein kinase proposed to be involved in bud-site selection, telomere uncapping and elongation, and transcription; component of the EKC/KEOPS protein complex with Kae1p, Cgi121p, Pcc1p, and Gon7p" Verified chr7:1016980-1017765 1016980-1017765 99.1% 284.98 220.80 254.17 186.14 116.82 51.35 252.89 220.15 84.08 0.93 0.89 0.35 -1.39 -1.11 Matched[2464]
YGR263C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum Uncharacterized chr7:1017973-1019247 1017973-1019247 99.0% 91.86 75.23 79.19 83.15 95.82 53.06 83.55 81.17 74.44 0.31 0.33 0.31 -0.12 0.21 Matched[2465]
YGR265W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF MES1/YGR264C, which encodes methionyl-tRNA synthetase" Dubious chr7:1021654-1022064 1021654-1022064 99.0% 235.97 201.56 201.56 189.27 41.79 44.24 218.76 195.41 43.02 0.81 0.79 0.18 -2.18 -0.51 Covered/w/another[2466]
YGR264C MES1 "Methionyl-tRNA synthetase, forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p, which increases the catalytic efficiency of both tRNA synthetases; also has a role in nuclear export of tRNAs" Verified chr7:1019604-1021859 1019604-1021859 99.1% 685.96 500.38 583.11 499.93 150.25 98.38 593.17 541.52 124.31 2.19 2.20 0.52 -2.12 -1.58 Matched[2466]
YGR266W "Protein of unknown function, predicted to contain a single transmembrane domain; localized to both the mitochondrial outer membrane and the plasma membrane" Verified chr7:1022662-1024767 1022662-1024767 98.7% 128.92 102.94 150.08 144.79 236.19 197.23 115.93 147.44 216.71 0.43 0.60 0.90 0.56 0.84 Matched[2467]
YGR267C FOL2 "GTP-cyclohydrolase I, catalyzes the first step in the folic acid biosynthetic pathway" Verified chr7:1025010-1025741 1025010-1025741 99.2% 834.28 861.81 693.86 614.01 894.85 523.15 848.05 653.93 709.00 3.13 2.65 2.94 0.12 -0.32 Matched[2468]
YGR269W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF HUA1/YGR268C" Dubious chr7:1026642-1026968 1026642-1026968 98.4% 24.85 40.38 46.60 27.96 86.98 80.77 32.62 37.28 83.87 0.12 0.15 0.35 1.17 0.47 Covered/w/another[2470]
YGR268C HUA1 Cytoplasmic protein containing a zinc finger domain with sequence similarity to that of Type I J-proteins; computational analysis of large-scale protein-protein interaction data suggests a possible role in actin patch assembly Verified chr7:1026063-1026659 1026063-1026659 98.4% 122.52 166.76 144.64 142.94 433.92 376.06 144.64 143.79 404.99 0.53 0.58 1.68 1.49 1.33 Matched[2469]
YGR270W YTA7 "Protein of unknown function, member of CDC48/PAS1/SEC18 family of ATPases, potentially phosphorylated by Cdc28p" Verified chr7:1027376-1031515 1027376-1031515 98.5% 162.82 186.60 153.50 144.43 186.36 212.35 174.71 148.96 199.35 0.64 0.60 0.83 0.42 0.90 Matched[2470]
YGR270C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified ORF YTA7/YGR270W" Dubious chr7:1027388-1027606 1027388-1027606 98.1% 46.57 88.47 116.41 74.51 46.57 149.01 67.52 95.46 97.79 0.25 0.39 0.41 0.03 NaN Covered/w/another[2470]
YGR271W SLH1 "Putative RNA helicase related to Ski2p, involved in translation inhibition of non-poly(A) mRNAs; required for repressing propagation of dsRNA viruses" Verified chr7:1031797-1037700 1031797-1037700 98.8% 56.89 61.52 48.15 43.01 30.67 49.01 59.21 45.58 39.84 0.22 0.19 0.17 -0.19 -0.03
YGR271C-A Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus Uncharacterized chr7:1037806-1037997 1037806-1037997 99.5% 340.39 178.05 225.18 178.05 26.18 10.47 259.22 201.61 18.33 0.96 0.82 0.08 -3.46 -2.58 Covered/w/another[2471]
YGR272C Putative protein of unknown function; deletion mutant has defects in pre-rRNA processing; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus Uncharacterized chr7:1038048-1038506 1038048-1038506 99.6% 183.81 126.91 126.91 133.48 39.39 8.75 155.36 130.20 24.07 0.57 0.53 0.10 -2.44 -2.90 Covered/w/another[2471]
YGR273C Putative protein of unknown function; deletion mutant has no readily detectable phenotype Uncharacterized chr7:1038720-1039244 1038720-1039244 99.1% 0.00 5.77 0.00 1.92 0.00 1.92 2.88 0.96 0.96 0.01 0.00 0.00 0.00 0.09 Overlap[2471]
YGR274C TAF1 "TFIID subunit (145 kDa), involved in RNA polymerase II transcription initiation, has histone acetyltransferase activity, involved in promoter binding and G1/S progression" Verified chr7:1039901-1043101 1039901-1043101 99.4% 104.39 102.19 86.47 81.75 69.49 61.32 103.29 84.11 65.40 0.38 0.34 0.27 -0.36 0.43 Matched[2472]
YGR275W RTT102 "Component of both the SWI/SNF and RSC chromatin remodeling complexes, suggested role in chromosome maintenance; possible weak regulator of Ty1 transposition" Verified chr7:1043282-1043755 1043282-1043755 98.1% 382.80 346.24 277.42 275.27 339.78 217.20 364.52 276.34 278.49 1.35 1.12 1.15 0.01 -0.37 Covered/w/another[2473]
YGR276C RNH70 "3' exoribonuclease, required for 5S rRNA and tRNA-Arg3 maturation" Verified chr7:1043825-1045486 1043825-1045486 99.3% 169.64 129.05 146.01 148.43 134.50 96.94 149.34 147.22 115.72 0.55 0.60 0.48 -0.35 -0.22 Covered/w/another[2473]
YGR277C "Putative pantetheine-phosphate adenylyltransferase (PPAT) that catalyzes the fourth step in the biosynthesis of coenzyme A from pantothenate; conserved in bacteria, humans, and plants; essential for viability" Uncharacterized chr7:1045650-1046567 1045650-1046567 99.1% 168.12 162.62 174.71 128.56 290.08 184.60 165.37 151.63 237.34 0.61 0.62 0.98 0.65 0.70 Covered/w/another[2473]
YGR278W CWC22 "Essential protein, component of a complex containing Cef1p, has similarity to S. pombe Cwf22p; putative spliceosomal component, based on computational analysis of large-scale protein-protein interaction data" Verified chr7:1046737-1048470 1046737-1048470 98.6% 71.91 85.95 71.33 71.33 74.84 68.99 78.93 71.33 71.91 0.29 0.29 0.30 0.01 0.39 Matched[2474]
YGR279C SCW4 Cell wall protein with similarity to glucanases; scw4 scw10 double mutants exhibit defects in mating Verified chr7:1048804-1049964 1048804-1049964 97.6% 4785.18 6111.16 4876.05 4936.04 3451.26 4188.80 5448.17 4906.04 3820.03 20.11 19.91 15.83 -0.36 -1.10 Frag>80[2475,2476,2477,2478]
YGR280C PXR1 "Essential protein involved in rRNA and snoRNA maturation; competes with TLC1 RNA for binding to Est2p, suggesting a role in regulation of telomerase; human homolog inhibits telomerase; contains a G-patch RNA interacting domain" Verified chr7:1050916-1051731 1050916-1051731 99.4% 526.59 314.48 302.14 265.15 176.35 110.99 420.53 283.64 143.67 1.55 1.15 0.60 -0.98 -0.89 Matched[2480]
YGR281W YOR1 "Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter mediates export of many different organic anions including oligomycin" Verified chr7:1052830-1057263 1052830-1057263 98.8% 132.67 135.41 123.54 115.78 193.42 264.66 134.04 119.66 229.04 0.49 0.49 0.95 0.94 1.38 Covered[2481]
YGR282C BGL2 "Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance" Verified chr7:1057789-1058730 1057789-1058730 98.6% 4220.92 4883.13 4268.29 4147.70 3791.29 3180.76 4552.02 4208.00 3486.02 16.80 17.08 14.44 -0.27 -0.58 Frag>80[2482,2483,2484]
YGR283C "Protein of unknown function; may interact with ribosomes, based on co-purification experiments; deletion mutant is resistant to fluconazole; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus" Verified chr7:1059021-1060046 1059021-1060046 99.1% 146.60 114.13 108.23 81.66 75.76 61.99 130.37 94.95 68.87 0.48 0.39 0.29 -0.46 -2.95 Frag>80[2484,2485,2486,2487]
YGR284C ERV29 "Protein localized to COPII-coated vesicles, involved in vesicle formation and incorporation of specific secretory cargo" Verified chr7:1060664-1061596 1060664-1061596 99.0% 580.09 505.41 585.50 560.61 1233.77 844.16 542.75 573.05 1038.96 2.00 2.33 4.30 0.86 0.84 Frag>80[2487,2488,2489]
YGR285C ZUO1 "Cytosolic ribosome-associated chaperone that acts, together with Ssz1p and the Ssb proteins, as a chaperone for nascent polypeptide chains; contains a DnaJ domain and functions as a J-protein partner for Ssb1p and Ssb2p" Verified chr7:1061858-1063159 1061858-1063159 99.0% 1870.09 1288.11 1700.15 1621.00 499.73 672.77 1579.10 1660.58 586.25 5.83 6.74 2.43 -1.50 -0.71 Matched[2490]
YGR286C BIO2 "Biotin synthase, catalyzes the conversion of dethiobiotin to biotin, which is the last step of the biotin biosynthesis pathway; complements E. coli bioB mutant" Verified chr7:1063819-1064946 1063819-1064946 99.2% 91.18 159.11 109.05 123.36 31.29 28.60 125.14 116.21 29.95 0.46 0.47 0.12 -1.96 -1.20 Matched[2491]
YGR287C "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; has similarity to alpha-D-glucosidase (maltase); authentic, non-tagged protein detected in purified mitochondria in high-throughput studies" Verified chr7:1067228-1068997 1067228-1068997 71.8% 16.53 18.89 22.83 17.32 61.41 41.72 17.71 20.07 51.56 0.07 0.08 0.21 1.36 1.52 Frag<80[2492]
YGR288W MAL13 "MAL-activator protein, part of complex locus MAL1; nonfunctional in genomic reference strain S288C" Verified chr7:1070299-1071720 1070299-1071720 98.7% 43.47 52.73 29.93 33.49 96.20 74.11 48.10 31.71 85.15 0.18 0.13 0.35 1.43 1.71 Matched[2493]
YGR290W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; putative HLH protein; partially overlaps the verified ORF MAL11/YGR289C (a high-affinity maltose transporter)" Dubious chr7:1075488-1075931 1075488-1075931 99.4% 11.33 36.25 29.45 36.25 47.57 40.78 23.79 32.85 44.18 0.09 0.13 0.18 0.43 NaN Covered/w/another[2494]
YGR289C MAL11 "Maltose permease, inducible high-affinity maltose transporter (alpha-glucoside transporter); encoded in the MAL1 complex locus; member of the 12 transmembrane domain superfamily of sugar transporters" Verified chr7:1073969-1075819 1073969-1075819 99.0% 42.01 67.11 47.47 53.47 94.40 75.84 54.56 50.47 85.12 0.20 0.20 0.35 0.75 0.99 Matched[2494]
YGR291C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr7:1076289-1076510 1076289-1076510 10.0% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.81
YGR292W MAL12 "Maltase (alpha-D-glucosidase), inducible protein involved in maltose catabolism; encoded in the MAL1 complex locus" Verified chr7:1076605-1078359 1076605-1078359 3.5% 0.00 0.00 16.48 0.00 0.00 16.48 0.00 8.24 8.24 0.00 0.03 0.03 0.00 -0.47
YGR294W Hypothetical protein Uncharacterized chr7:1080312-1080674 1080312-1080674 1.1% 247.42 0.00 0.00 0.00 0.00 0.00 123.71 0.00 0.00 0.46 0.00 0.00 NaN 0.96
YGR293C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YGR294W" Dubious chr7:1079891-1080352 1079891-1080352 6.6% 32.56 0.00 32.56 0.00 0.00 32.56 16.28 16.28 16.28 0.06 0.07 0.07 0.00 -0.73
YGR295C COS6 "Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" Verified chr7:1081590-1082735 1081590-1082735 21.3% 461.85 564.03 543.60 429.16 727.52 371.93 512.94 486.38 549.73 1.89 1.97 2.28 0.18 0.33 Frag<80[2495,2496]
YGR296W YRF1-3 "Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p" Verified chr7:1084870-1090597 1084870-1084888,1085037-1090597 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.20
YGR296C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps TEL07R" Dubious chr7:1088876-1089451 1088876-1089451 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YGR296C-B "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; contained completely within TEL07R" Dubious chr7:1089752-1090234 1089752-1090234 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YHL050W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr8:811-1293 811-1293 1.0% 0.00 198.35 0.00 0.00 0.00 0.00 99.17 0.00 0.00 0.37 0.00 0.00 NaN NaN
YHL050C "Putative protein of unknown function, potential Cdc28p substrate" Uncharacterized chr8:445-3310 445-1897,2670-3310 1.2% 0.00 80.00 0.00 0.00 40.00 0.00 40.00 0.00 20.00 0.15 0.00 0.08 Inf 0.32
YHL049C Putative protein of unknown function Uncharacterized chr8:3725-4540 3725-4540 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.14
YHL048C-A Putative protein of unknown function; identified by expression profiling and mass spectrometry Uncharacterized chr8:5662-5796 5662-5796 45.8% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN NaN
YHL048W COS8 "Nuclear membrane protein, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; regulation suggests a potential role in the unfolded protein response" Verified chr8:6400-7545 6400-7545 43.9% 182.71 291.93 236.33 222.42 351.51 248.24 237.32 229.38 299.88 0.88 0.93 1.24 0.39 0.79 Frag>80[2498,2499,2500]
YHL046W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr8:9979-10305 9979-10305 99.0% 98.80 55.58 49.40 43.23 21.61 21.61 77.19 46.31 21.61 0.28 0.19 0.09 -1.10 NaN Covered/w/another[2501]
YHL047C ARN2 "Transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; responsible for uptake of iron bound to the siderophore triacetylfusarinine C" Verified chr8:8298-10211 8298-10211 98.8% 126.87 111.01 90.40 60.79 53.92 40.70 118.94 75.59 47.31 0.44 0.31 0.20 -0.68 -0.05 Covered/w/another[2501]
YHL046C Putative protein of unknown function; not an essential gene Uncharacterized chr8:11921-12283 11921-12283 6.4% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.70
YHL045W Putative protein of unknown function; not an essential gene Dubious chr8:12500-12847 12500-12847 63.3% 4.54 18.16 18.16 9.08 18.16 13.62 11.35 13.62 15.89 0.04 0.06 0.07 0.22 0.11
YHL044W "Putative integral membrane protein, member of DUP240 gene family; green fluorescent protein (GFP)-fusion protein localizes to the plasma membrane in a punctate pattern" Uncharacterized chr8:13563-14270 13563-14270 99.0% 89.89 117.00 97.03 119.86 255.41 164.09 103.45 108.44 209.75 0.38 0.44 0.87 0.95 1.36 Matched[2502]
YHL043W ECM34 "Putative protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" Verified chr8:14899-15411 14899-15411 98.9% 35.48 55.19 47.31 31.54 112.35 80.81 45.34 39.42 96.58 0.17 0.16 0.40 1.29 -0.01 Covered/w/another[2503]
YHL042W "Putative protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" Uncharacterized chr8:15665-16117 15665-16117 99.1% 31.20 13.37 24.51 4.46 84.69 80.23 22.29 14.49 82.46 0.08 0.06 0.34 2.51 1.84 Covered/w/another[2503]
YHL041W "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data" Dubious chr8:17390-17839 17390-17839 99.1% 2.24 2.24 0.00 0.00 0.00 13.46 2.24 0.00 6.73 0.01 0.00 0.03 Inf 0.15
YHL040C ARN1 "Transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; responsible for uptake of iron bound to ferrirubin, ferrirhodin, and related siderophores" Verified chr8:19085-20968 19085-20968 98.7% 101.59 73.64 78.48 33.33 36.02 23.65 87.62 55.90 29.83 0.32 0.23 0.12 -0.91 -0.36 Matched[2504]
YHL039W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr8:21780-23537 21780-23537 99.1% 210.13 138.36 140.09 137.79 28.13 23.54 174.25 138.94 25.84 0.64 0.56 0.11 -2.43 -1.82 Matched[2505]
YHL038C CBP2 "Mitochondrial protein required for splicing of the group I intron aI5 of the COB pre-mRNA, binds to the RNA to promote splicing; also involved in but not essential for splicing of the COB bI2 intron and the intron in the 21S rRNA gene" Verified chr8:23614-25506 23614-25506 99.1% 67.73 81.06 63.46 59.73 49.60 42.66 74.40 61.60 46.13 0.27 0.25 0.19 -0.42 -0.07 Matched[2506]
YHL037C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr8:25698-26177 25698-26177 98.8% 6.33 0.00 4.22 2.11 27.41 8.43 3.16 3.16 17.92 0.01 0.01 0.07 2.50 0.88 Covered/w/another[2507]
YHL036W MUP3 "Low affinity methionine permease, similar to Mup1p" Verified chr8:26239-27879 26239-27879 99.0% 49.26 61.58 80.67 48.65 74.51 44.95 55.42 64.66 59.73 0.20 0.26 0.25 -0.11 0.24 Frag>80[2507]
YHL035C VMR1 "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; member of the ATP-binding cassette (ABC) family; potential Cdc28p substrate; detected in purified mitochondria in high-throughput studies" Verified chr8:27976-32754 27976-32754 99.1% 76.62 62.69 77.26 49.18 105.33 112.93 69.66 63.22 109.13 0.26 0.26 0.45 0.79 1.21 Matched[2508]
YHL034W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr8:33174-33635 33174-33635 99.3% 2739.31 2710.98 2702.26 2632.53 2809.04 2144.37 2725.14 2667.39 2476.71 10.06 10.83 10.26 -0.11 NaN Matched[2509]
YHL034C SBP1 Nucleolar single-strand nucleic acid binding protein; associates with small nuclear RNAs Verified chr8:33191-34075 33191-34075 99.3% 2402.05 2379.28 2343.99 2265.44 2263.16 1874.96 2390.67 2304.72 2069.06 8.83 9.36 8.57 -0.16 -0.44 Matched[2509]
YHL033C RPL8A "Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Bp and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits" Verified chr8:35253-36023 35253-36023 46.3% 3650.29 2916.31 2938.72 2361.62 593.91 296.95 3283.30 2650.17 445.43 12.12 10.76 1.85 -2.57 -2.27 Matched[2511]
YHL032C GUT1 "Glycerol kinase, converts glycerol to glycerol-3-phosphate; glucose repression of expression is mediated by Adr1p and Ino2p-Ino4p; derepression of expression on non-fermentable carbon sources is mediated by Opi1p and Rsf1p" Verified chr8:36377-38506 36377-38506 98.7% 126.53 179.81 150.79 141.75 180.76 152.22 153.17 146.27 166.49 0.57 0.59 0.69 0.19 0.33 Matched[2512]
YHL030W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene GOS1/YHL031C" Dubious chr8:39072-39533 39072-39533 98.7% 155.74 208.39 221.55 171.10 258.84 272.00 182.07 196.33 265.42 0.67 0.80 1.10 0.44 NaN Matched[2513]
YHL031C GOS1 "v-SNARE protein involved in Golgi transport, homolog of the mammalian protein GOS-28/GS28" Verified chr8:38813-39484 38813-39484 98.6% 165.96 232.35 212.74 182.56 297.23 262.53 199.16 197.65 279.88 0.74 0.80 1.16 0.50 0.61 Matched[2513]
YHL030W ECM29 "Major component of the proteasome; tethers the proteasome core particle to the regulatory particle, and enhances the stability of the proteasome" Verified chr8:40082-45688 40082-45688 99.0% 74.06 56.76 65.05 61.80 102.53 119.10 65.41 63.43 110.81 0.24 0.26 0.46 0.81 0.95 Frag>80[2514,2515,2516]
YHL029C "Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts" Uncharacterized chr8:45927-47966 45927-47966 98.7% 116.74 79.48 89.91 70.54 68.06 60.11 98.11 80.23 64.08 0.36 0.33 0.27 -0.32 0.05 Matched[2517]
YHL028W WSC4 ER membrane protein involved in the translocation of soluble secretory proteins and insertion of membrane proteins into the ER membrane; may also have a role in the stress response but has only partial functional overlap with WSC1-3 Verified chr8:48761-50578 48761-50578 98.9% 274.14 380.35 226.32 247.45 137.91 130.12 327.25 236.89 134.01 1.21 0.96 0.56 -0.82 -0.22 Matched[2519]
YHL027W RIM101 Transcriptional repressor involved in response to pH and in cell wall construction; required for alkaline pH-stimulated haploid invasive growth and sporulation; activated by proteolytic processing; similar to A. nidulans PacC Verified chr8:51109-52986 51109-52986 98.7% 154.35 206.70 145.71 119.27 202.38 194.28 180.52 132.49 198.33 0.67 0.54 0.82 0.58 0.91 Matched[2520]
YHL026C Putative protein of unknown function; YHL026C is not an essential gene; in 2005 the start site was moved 141 nt upstream (see Locus History) Uncharacterized chr8:53217-54164 53217-54164 98.6% 58.85 90.95 47.08 47.08 26.75 14.98 74.90 47.08 20.86 0.28 0.19 0.09 -1.17 -0.12 Matched[2521]
YHL025W SNF6 Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf5p Verified chr8:54849-55847 54849-55847 98.1% 260.28 293.97 238.85 231.70 287.84 149.02 277.12 235.27 218.43 1.02 0.96 0.91 -0.11 -0.12 Matched[2522]
YHL024W RIM4 Putative RNA-binding protein required for the expression of early and middle sporulation genes Verified chr8:56647-58788 56647-58788 98.5% 53.53 60.64 50.69 44.06 315.98 207.97 57.08 47.37 261.97 0.21 0.19 1.09 2.47 2.31 Matched[2523]
YHL023C RMD11 Protein required for sporulation Verified chr8:59121-62561 59121-62561 99.1% 102.59 102.00 87.93 81.19 92.92 105.52 102.30 84.56 99.22 0.38 0.34 0.41 0.23 0.52 Matched[2524]
YHL022C SPO11 Meiosis-specific protein that initiates meiotic recombination by catalyzing the formation of double-strand breaks in DNA via a transesterification reaction; required for homologous chromosome pairing and synaptonemal complex formation Verified chr8:62959-64155 62959-64155 98.9% 10.13 23.64 11.82 7.60 16.04 27.86 16.89 9.71 21.95 0.06 0.04 0.09 1.18 -0.02
YHL021C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr8:64459-65856 64459-65856 98.9% 196.76 467.30 509.25 721.92 3970.58 3457.71 332.03 615.59 3714.15 1.23 2.50 15.39 2.59 2.54 Frag>80[2525,2526,2527]
YHL020C OPI1 Transcriptional regulator of a variety of genes; phosphorylation by protein kinase A stimulates Opi1p function in negative regulation of phospholipid biosynthetic genes; involved in telomere maintenance Verified chr8:66239-67453 66239-67453 98.0% 184.84 191.56 209.21 215.93 126.03 128.55 188.20 212.57 127.29 0.69 0.86 0.53 -0.74 -0.21 Frag>80[2527,2528]
YHL019W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene APM2/YHL019C" Dubious chr8:67708-68301 67708-68301 99.0% 90.14 132.65 137.76 93.54 290.82 187.07 111.39 115.65 238.95 0.41 0.47 0.99 1.05 NaN Covered/w/another[2529]
YHL019C APM2 "Protein of unknown function, homologous to the medium chain of mammalian clathrin-associated protein complex; involved in vesicular transport" Verified chr8:67728-69545 67728-69545 99.2% 83.74 103.15 94.83 76.53 175.79 146.96 93.44 85.68 161.38 0.34 0.35 0.67 0.91 1.25 Matched[2529]
YHL018W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria and is induced in response to the DNA-damaging agent MMS Uncharacterized chr8:69705-70067 69705-70067 98.3% 19.61 33.61 33.61 33.61 36.41 25.21 26.61 33.61 30.81 0.10 0.14 0.13 -0.13 0.43 Covered/w/another[2530]
YHL017W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein co-localizes with clathrin-coated vesicles Uncharacterized chr8:70273-71871 70273-71871 99.0% 163.04 180.10 139.02 162.41 187.05 180.10 171.57 150.71 183.58 0.63 0.61 0.76 0.28 0.66 Matched[2530]
YHL016C DUR3 "Plasma membrane transporter for both urea and polyamines, expression is highly sensitive to nitrogen catabolite repression and induced by allophanate, the last intermediate of the allantoin degradative pathway" Verified chr8:72034-74241 72034-74241 98.9% 43.05 61.83 30.68 24.73 27.94 21.98 52.44 27.71 24.96 0.19 0.11 0.10 -0.15 -0.46 Frag<80[2531]
YHL015W-A Putative protein of unknown function Uncharacterized chr8:74696-74779 74696-74779 99.0% 0.00 0.00 0.00 12.02 84.17 12.02 0.00 6.01 48.10 0.00 0.02 0.20 3.00 NaN Covered[2532]
YHL015W RPS20 Protein component of the small (40S) ribosomal subunit; overproduction suppresses mutations affecting RNA polymerase III-dependent transcription; has similarity to E. coli S10 and rat S20 ribosomal proteins Verified chr8:75409-75774 75409-75774 98.7% 14628.68 12530.17 12992.50 11710.69 7051.33 6184.80 13579.42 12351.60 6618.06 50.13 50.14 27.42 -0.90 -2.92 Matched[2533]
YHL014C YLF2 "Protein of unknown function, has weak similarity to E. coli GTP-binding protein gtp1; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr8:76094-77311 76094-77311 99.3% 109.94 109.94 77.70 80.18 33.89 33.89 109.94 78.94 33.89 0.41 0.32 0.14 -1.22 -0.79 Covered/w/another[2534]
YHL013C OTU2 "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; member of the ovarian tumor-like (OTU) superfamily of predicted cysteine proteases; shows cytoplasmic localization" Verified chr8:77427-78350 77427-78350 99.5% 138.17 81.60 115.33 95.74 73.98 38.08 109.89 105.54 56.03 0.41 0.43 0.23 -0.91 -0.00 Covered/w/another[2534]
YHL012W "Putative protein of unknown function, has some homology to Ugp1p, which encodes UDP-glucose pyrophosphorylase" Uncharacterized chr8:78932-80413 78932-80413 99.0% 38.86 40.90 14.32 13.63 11.59 11.59 39.88 13.98 11.59 0.15 0.06 0.05 -0.27 0.06 Frag<80[2535]
YHL011C PRS3 "5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes" Verified chr8:80650-81612 80650-81612 99.1% 651.93 478.99 543.98 523.02 100.62 88.04 565.46 533.50 94.33 2.09 2.17 0.39 -2.50 -2.07 Matched[2536]
YHL010C "Putative protein of unknown function, contains a zinc finger region and has homology to human BRAP2, which is a cytoplasmic protein that binds nuclear localization sequences" Uncharacterized chr8:81960-83717 81960-83717 99.3% 86.53 108.31 95.13 97.42 135.81 125.50 97.42 96.27 130.66 0.36 0.39 0.54 0.44 0.86 Covered/w/another[2537]
YHL009C YAP3 Basic leucine zipper (bZIP) transcription factor Verified chr8:84064-85056 84064-85056 99.2% 119.79 135.02 126.90 129.94 130.96 97.46 127.41 128.42 114.21 0.47 0.52 0.47 -0.17 0.32 Covered/w/another[2537]
YHL008C "Putative protein of unknown function, does not appear to be involved in monocarboxylic acid transport; green fluorescent protein (GFP)-fusion protein localizes to the vacuole" Uncharacterized chr8:92623-94506 92623-94506 99.0% 108.29 156.53 87.92 92.20 344.16 407.95 132.41 90.06 376.06 0.49 0.37 1.56 2.06 2.22 Matched[2539]
YHL006W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr8:97728-98081 97728-98081 98.8% 102.91 80.04 88.61 68.60 54.31 65.75 91.47 78.61 60.03 0.34 0.32 0.25 -0.39 NaN Covered/w/another[2541]
YHL007C STE20 "Signal transducing kinase of the PAK (p21-activated kinase) family, involved in pheromone response and pseudohyphal/invasive growth pathways, activated by Cdc42p; binds Ste4p at a GBB motif present in noncatalytic domains of PAK kinases" Verified chr8:95114-97933 95114-97933 98.9% 181.10 186.47 158.50 134.84 101.13 118.70 183.79 146.67 109.91 0.68 0.60 0.46 -0.42 0.36 Frag<80[2540]
YHL006C SHU1 "Protein of unassigned function involved in mutation suppression, important for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation; associates with Shu2p, Psy3p, and Csm2p" Verified chr8:98339-98791 98339-98791 98.7% 55.90 62.60 46.95 62.60 127.45 69.31 59.25 54.78 98.38 0.22 0.22 0.41 0.84 0.24 Covered/w/another[2541]
YHL004W MRP4 Mitochondrial ribosomal protein of the small subunit Verified chr8:99215-100399 99215-100399 98.7% 364.18 342.81 387.26 357.34 266.72 228.25 353.49 372.30 247.49 1.30 1.51 1.03 -0.59 0.47 Matched[2542]
YHL005C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YHL004W" Dubious chr8:98824-99216 98824-99216 98.7% 25.78 38.67 46.40 54.14 41.25 30.93 32.22 50.27 36.09 0.12 0.20 0.15 -0.48 -0.14 Overlap[2541,2542]
YHL003C LAG1 "Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lac1p" Verified chr8:100644-101879 100644-101879 99.1% 665.33 666.96 635.12 609.82 555.94 364.91 666.15 622.47 460.42 2.46 2.53 1.91 -0.44 -0.56 Matched[2543]
YHL002W HSE1 "Subunit of the endosomal Vps27p-Hse1p complex required for sorting of ubiquitinated membrane proteins into intralumenal vesicles prior to vacuolar degradation, as well as for recycling of Golgi proteins and formation of lumenal membranes" Verified chr8:102607-103965 102607-103965 98.6% 234.27 249.94 243.97 199.20 235.02 186.52 242.10 221.59 210.77 0.89 0.90 0.87 -0.07 0.05 Matched[2544]
YHL002C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr8:102582-103070 102582-103070 98.6% 211.65 174.30 197.13 161.85 190.90 157.70 192.98 179.49 174.30 0.71 0.73 0.72 -0.04 NaN Covered/w/another[2544]
YHL001W RPL14B "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl14Ap and has similarity to rat L14 ribosomal protein" Verified chr8:104272-105086 104272-104400,104799-105086 43.2% 2776.49 1821.38 2360.02 1554.84 960.67 533.09 2298.94 1957.43 746.88 8.49 7.95 3.09 -1.39 -1.95 Frag>80[2545,2546,2547]
YHR001W OSH7 "Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability" Verified chr8:106050-107363 106050-107363 98.5% 187.74 219.41 222.50 214.00 332.21 264.99 203.57 218.25 298.60 0.75 0.89 1.24 0.45 0.66 Matched[2548]
YHR001W-A QCR10 "Subunit of the ubiqunol-cytochrome c oxidoreductase complex which includes Cobp, Rip1p, Cyt1p, Cor1p, Qcr2p, Qcr6p, Qcr7p, Qcr8p, Qcr9p, and Qcr10p and comprises part of the mitochondrial respiratory chain" Verified chr8:107821-108117 107821-107826,107890-108117 98.9% 453.56 539.96 609.07 647.95 1688.98 1239.74 496.76 628.51 1464.36 1.83 2.55 6.07 1.22 0.70 Matched[2550]
YHR002W LEU5 "Mitochondrial carrier protein involved in the accumulation of CoA in the mitochondrial matrix; homolog of human Graves disease protein; does not encode an isozyme of Leu4p, as first hypothesized" Verified chr8:108807-109880 108807-109880 98.9% 58.35 64.00 69.64 67.76 123.29 83.76 61.17 68.70 103.53 0.23 0.28 0.43 0.59 0.33 Covered/w/another[2551]
YHR003C "Protein of unknown function, localized to the mitochondrial outer membrane" Verified chr8:110023-111312 110023-111312 99.1% 171.26 160.31 145.45 132.94 112.61 81.33 165.79 139.20 96.97 0.61 0.57 0.40 -0.52 -0.11 Covered/w/another[2551]
YHR004C NEM1 "Catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme, which regulates nuclear growth by controlling recruitment of Pah1p onto promoters of phospholipid biosynthetic genes; required for normal nuclear envelope morphology and sporulation" Verified chr8:111749-113089 111749-113089 99.1% 103.07 188.83 120.37 143.69 218.93 136.17 145.95 132.03 177.55 0.54 0.54 0.74 0.43 0.74 Covered/w/another[2551]
YHR005C GPA1 GTP-binding alpha subunit of the heterotrimeric G protein that couples to pheromone receptors; negatively regulates the mating pathway by sequestering G(beta)gamma and by triggering an adaptive response; activates Vps34p at the endosome Verified chr8:113494-114912 113494-114912 99.4% 357.16 416.69 376.30 369.21 240.23 133.23 386.93 372.75 186.73 1.43 1.51 0.77 -1.00 -0.89 Frag>80[2552,2553]
YHR005C-A MRS11 "Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that mediates insertion of hydrophobic proteins at the inner membrane, has homology to Mrs5p, which is also involved in this process" Verified chr8:115615-115896 115615-115896 99.3% 2609.94 2395.72 2477.83 2306.46 1556.68 1017.55 2502.83 2392.15 1287.12 9.24 9.71 5.33 -0.89 -2.08 Matched[2554]
YHR006W STP2 "Transcription factor, activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes" Verified chr8:117809-119434 117809-119434 98.7% 103.46 105.33 99.10 95.36 203.18 161.43 104.40 97.23 182.30 0.39 0.39 0.76 0.91 1.19 Matched[2555]
YHR007C ERG11 "Lanosterol 14-alpha-demethylase, catalyzes the C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in the ergosterol biosynthesis pathway; member of the cytochrome P450 family" Verified chr8:120086-121678 120086-121678 98.8% 1868.68 2499.40 1424.69 1406.27 645.97 527.19 2184.04 1415.48 586.58 8.06 5.75 2.43 -1.27 -1.06 Matched[2557]
YHR007C-A Putative protein of unknown function; identified by expression profiling and mass spectrometry Uncharacterized chr8:122545-122760 122545-122760 98.1% 99.13 160.50 122.74 61.37 472.07 240.76 129.82 92.05 356.41 0.48 0.37 1.48 1.95 NaN Matched[2559]
YHR008C SOD2 "Mitochondrial superoxide dismutase, protects cells against oxygen toxicity; phosphorylated" Verified chr8:122884-123585 122884-123585 98.6% 1164.11 1403.86 1389.42 1387.98 4393.57 3953.06 1283.99 1388.70 4173.32 4.74 5.64 17.29 1.59 1.40 Matched[2560]
YHR009C Putative protein of unknown function; not an essential gene Uncharacterized chr8:124104-125675 124104-125675 98.8% 573.82 647.24 529.38 456.61 501.69 488.17 610.53 493.00 494.93 2.25 2.00 2.05 0.01 0.29 Matched[2562]
YHR010W RPL27A "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Bp and has similarity to rat L27 ribosomal protein" Verified chr8:126515-127486 126515-126545,127107-127486 90.5% 10690.57 8136.23 9157.96 7757.11 2274.70 1833.74 9413.40 8457.54 2054.22 34.75 34.33 8.51 -2.04 -2.71 Matched[2563]
YHR011W DIA4 "Probable mitochondrial seryl-tRNA synthetase, mutant displays increased invasive and pseudohyphal growth" Verified chr8:127774-129114 127774-129114 98.4% 67.42 86.36 67.42 56.06 81.06 37.12 76.89 61.74 59.09 0.28 0.25 0.24 -0.06 0.19 Matched[2564]
YHR012W VPS29 Endosomal protein that is a subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde transport; forms a subcomplex with Vps35p and Vps26p that selects cargo proteins for endosome-to-Golgi retrieval Verified chr8:129475-130442 129475-129522,129642-130442 98.5% 261.87 248.72 222.41 194.91 412.54 263.07 255.29 208.66 337.80 0.94 0.85 1.40 0.70 0.10 Matched[2565]
YHR013C ARD1 "Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing" Verified chr8:130724-131440 130724-131440 99.0% 390.05 368.93 353.44 340.77 176.02 136.59 379.49 347.10 156.30 1.40 1.41 0.65 -1.15 -0.76 Matched[2566]
YHR014W SPO13 "Meiosis-specific protein, involved in maintaining sister chromatid cohesion during meiosis I as well as promoting proper attachment of kinetochores to the spindle during meiosis I and meiosis II" Verified chr8:132040-132915 132040-132915 99.0% 17.30 14.99 16.14 16.14 19.60 13.84 16.14 16.14 16.72 0.06 0.07 0.07 0.05 -0.31
YHR015W MIP6 "Putative RNA-binding protein, interacts with Mex67p, which is a component of the nuclear pore involved in nuclear mRNA export" Verified chr8:134547-136526 134547-136526 98.9% 6.13 4.09 3.06 3.57 9.70 7.15 5.11 3.32 8.43 0.02 0.01 0.03 1.34 0.48 Overlap[2567]
YHR016C YSC84 Protein involved in the organization of the actin cytoskeleton; contains SH3 domain similar to Rvs167p Verified chr8:136874-138448 136874-138233,138402-138448 98.9% 199.72 308.21 279.47 295.28 760.82 737.83 253.97 287.37 749.33 0.94 1.17 3.10 1.38 1.79 Covered/w/another[2567]
YHR017W YSC83 "Non-essential mitochondrial protein of unknown function; mRNA induced during meiosis, peaking between mid to late prophase of meiosis I; similar to S. douglasii YSD83" Verified chr8:138687-139844 138687-139844 98.9% 121.33 141.41 122.20 102.13 403.27 310.75 131.37 112.17 357.01 0.48 0.46 1.48 1.67 1.01 Covered/w/another[2567]
YHR018C ARG4 "Argininosuccinate lyase, catalyzes the final step in the arginine biosynthesis pathway" Verified chr8:140004-141395 140004-141395 99.1% 392.16 1119.21 403.76 523.36 356.64 286.33 755.69 463.56 321.48 2.79 1.88 1.33 -0.53 -0.22 Covered/w/another[2567]
YHR019C DED81 "Cytosolic asparaginyl-tRNA synthetase, required for protein synthesis, catalyzes the specific attachment of asparagine to its cognate tRNA" Verified chr8:141887-143551 141887-143551 98.8% 1493.31 1462.93 1396.68 1411.26 385.94 432.74 1478.12 1403.97 409.34 5.46 5.70 1.70 -1.78 -1.04 Frag>80[2568,2569]
YHR020W "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; has similarity to proline-tRNA ligase; YHR020W is an essential gene" Verified chr8:143989-146055 143989-146055 98.6% 743.47 550.25 564.47 479.14 75.52 33.84 646.86 521.80 54.68 2.39 2.12 0.23 -3.25 -2.53 Matched[2570]
YHR021C RPS27B Protein component of the small (40S) ribosomal subunit; nearly identical to Rps27Ap and has similarity to rat S27 ribosomal protein Verified chr8:147864-148662 147864-148109,148660-148662 96.6% 9843.70 8030.50 9190.78 7523.13 2391.27 1480.51 8937.10 8356.96 1935.89 32.99 33.92 8.02 -2.11 -3.07 Matched[2572]
YHR021W-A ECM12 Non-essential protein of unknown function Uncharacterized chr8:149218-149673 149218-149673 99.2% 28.73 72.93 39.78 19.89 212.15 165.75 50.83 29.83 188.95 0.19 0.12 0.78 2.66 -0.44 Covered/w/another[2573]
YHR022C Putative protein of unknown function; YHR022C is not an essential gene. Uncharacterized chr8:149568-150338 149568-150338 99.1% 54.97 81.14 34.03 40.57 151.82 180.61 68.06 37.30 166.21 0.25 0.15 0.69 2.16 3.44 Covered/w/another[2573]
YHR022C-A "Putative protein of unknown function, identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr8:151210-151299 151210-151299 98.8% 0.00 44.99 11.25 22.49 33.74 22.49 22.49 16.87 28.12 0.08 0.07 0.12 0.74 NaN Covered/w/another[2573]
YHR023W MYO1 "Type II myosin heavy chain, required for wild-type cytokinesis and cell separation; localizes to the actomyosin ring; binds to myosin light chains Mlc1p and Mlc2p through its IQ1 and IQ2 motifs respectively" Verified chr8:151659-157445 151659-157445 98.8% 144.36 157.83 123.19 114.09 79.97 101.31 151.10 118.64 90.64 0.56 0.48 0.38 -0.39 -0.13 Covered/w/another[2574]
YHR024C MAS2 "Larger subunit of the mitochondrial processing protease (MPP), essential processing enzyme that cleaves the N-terminal targeting sequences from mitochondrially imported proteins" Verified chr8:157737-159185 157737-159185 99.1% 217.36 184.62 213.18 190.89 147.00 133.07 200.99 202.04 140.03 0.74 0.82 0.58 -0.53 0.02 Covered/w/another[2574]
YHR025W THR1 "Homoserine kinase, conserved protein required for threonine biosynthesis; expression is regulated by the GCN4-mediated general amino acid control pathway" Verified chr8:159431-160504 159431-160504 98.9% 838.17 901.27 795.79 792.97 226.97 245.80 869.72 794.38 236.38 3.21 3.22 0.98 -1.75 -0.76 Matched[2575]
YHR026W PPA1 "Subunit c'' of the vacuolar ATPase, which functions in acidification of the vacuole; one of three proteolipid subunits of the V0 domain" Verified chr8:160837-161478 160837-161478 99.0% 1631.25 1922.27 1639.12 1670.58 1039.78 869.90 1776.76 1654.85 954.84 6.56 6.72 3.96 -0.79 -0.47 Matched[2576]
YHR027C RPN1 "Non-ATPase base subunit of the 19S regulatory particle of the 26S proteasome; may participate in the recognition of several ligands of the proteasome; contains a leucine-rich repeat (LRR) domain, a site for protein?protein interactions" Verified chr8:161723-164704 161723-164704 99.2% 473.73 377.02 466.97 462.91 484.89 514.31 425.38 464.94 499.60 1.57 1.89 2.07 0.10 0.27 Covered/w/another[2577]
YHR028W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr8:167345-167665 167345-167665 97.7% 57.42 70.18 108.45 92.50 63.80 63.80 63.80 100.48 63.80 0.24 0.41 0.26 -0.66 NaN Overlap[2577,2578]
YHR028C DAP2 "Dipeptidyl aminopeptidase, synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p" Verified chr8:164971-167427 164971-167427 99.1% 282.42 308.69 266.00 288.58 378.48 391.61 295.56 277.29 385.04 1.09 1.13 1.60 0.47 0.76 Covered/w/another[2577]
YHR029C YHI9 "Protein of unknown function that is a member of the PhzF superfamily, although unlike its bacterial homolog, is most likely not involved in phenazine production; possibly involved in a membrane regulation metabolic pathway" Verified chr8:167670-168554 167670-168554 99.0% 169.98 271.51 195.08 168.84 254.40 167.70 220.74 181.96 211.05 0.81 0.74 0.87 0.21 0.23 Matched[2578]
YHR030C SLT2 Serine/threonine MAP kinase involved in regulating the maintenance of cell wall integrity and progression through the cell cycle; regulated by the PKC1-mediated signaling pathway Verified chr8:168883-170337 168883-170337 97.7% 211.71 204.68 183.58 155.44 437.49 320.03 208.19 169.51 378.76 0.77 0.69 1.57 1.16 0.93 Matched[2579]
YHR031C RRM3 DNA helicase involved in rDNA replication and Ty1 transposition; relieves replication fork pauses at telomeric regions; structurally and functionally related to Pif1p Verified chr8:170792-172963 170792-172963 99.2% 79.84 84.48 61.73 49.20 42.24 46.42 82.16 55.47 44.33 0.30 0.23 0.18 -0.32 -0.02 Matched[2580]
YHR032W Putative protein of unknown function; putative substrate of the cAMP-dependent protein kinase (PKA) Uncharacterized chr8:173337-175082 173337-175082 98.4% 206.65 190.35 136.79 113.51 105.36 107.69 198.50 125.15 106.52 0.73 0.51 0.44 -0.23 0.21 Covered/w/another[2581]
YHR032W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YHR032C-A" Dubious chr8:175188-175367 175188-175367 98.9% 331.38 286.45 252.75 241.52 207.82 162.88 308.92 247.13 185.35 1.14 1.00 0.77 -0.42 NaN Covered/w/another[2581]
YHR032C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YHR032W-A" Dubious chr8:175268-175387 175268-175387 99.0% 345.26 294.74 277.89 193.68 210.53 218.95 320.00 235.79 214.74 1.18 0.96 0.89 -0.13 NaN Covered/w/another[2581]
YHR033W Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm Uncharacterized chr8:175541-176812 175541-176812 98.4% 83.06 77.47 106.22 91.84 179.69 92.64 80.26 99.03 136.16 0.30 0.40 0.56 0.46 0.37 Covered/w/another[2581]
YHR034C PIH1 "Protein of unresolved function; may function in protein folding and/or rRNA processing, interacts with a chaperone (Hsp82p), two chromatin remodeling factors (Rvb1p, Rvb2p) and two rRNA processing factors (Rrp43p, Nop58p)" Verified chr8:176958-177992 176958-177992 98.9% 77.17 77.17 78.14 72.28 117.22 72.28 77.17 75.21 94.75 0.28 0.31 0.39 0.33 0.72 Covered/w/another[2581]
YHR035W Putative protein of unknown function; not an essential gene Uncharacterized chr8:178212-180104 178212-180104 99.0% 20.27 25.07 19.74 14.40 26.67 9.07 22.67 17.07 17.87 0.08 0.07 0.07 0.07 -1.06 Frag<80[2582]
YHR036W BRL1 "Essential nuclear envelope integral membrane protein identified as a suppressor of a cold-sensitive mutant of CRM1, a karyopherin; homologous to and interacts with Brr6p, which is a nuclear envelope protein involved in nuclear export" Verified chr8:180338-181753 180338-181753 98.6% 72.34 53.00 68.05 28.65 32.95 25.79 62.67 48.35 29.37 0.23 0.20 0.12 -0.72 -0.21 Covered[2583]
YHR037W PUT2 "Delta-1-pyrroline-5-carboxylate dehydrogenase, nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; deficiency of the human homolog causes HPII, an autosomal recessive inborn error of metabolism" Verified chr8:181970-183697 181970-183697 98.8% 310.92 276.37 340.78 346.64 483.07 412.80 293.65 343.71 447.94 1.08 1.40 1.86 0.38 0.55 Matched[2584]
YHR038W RRF1 "Mitochondrial ribosome recycling factor, essential for mitochondrial protein synthesis and for the maintenance of the respiratory function of mitochondria" Verified chr8:184059-184751 184059-184751 98.7% 114.00 116.92 168.08 154.92 210.46 116.92 115.46 161.50 163.69 0.43 0.66 0.68 0.02 -0.12 Matched[2585]
YHR039C MSC7 "Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc7 mutants are defective in directing meiotic recombination events to homologous chromatids" Verified chr8:184868-186802 184868-186802 98.9% 435.61 472.70 458.07 415.24 186.99 135.80 454.16 436.66 161.40 1.68 1.77 0.67 -1.44 -1.11 Matched[2586]
YHR039C-A VMA10 "Vacuolar H+ ATPase subunit G of the catalytic (V1) sector, involved in vacuolar acidification" Verified chr8:187166-187672 187166-187507,187670-187672 99.4% 2782.02 3085.30 2455.41 2265.86 2286.27 1458.08 2933.66 2360.63 1872.17 10.83 9.58 7.76 -0.33 -1.06 Covered/w/another[2587]
YHR040W BCD1 Essential protein required for the accumulation of box C/D snoRNA Verified chr8:187917-189017 187917-189017 97.9% 81.61 63.99 51.01 56.57 11.13 25.04 72.80 53.79 18.08 0.27 0.22 0.07 -1.57 -1.28 Covered/w/another[2587]
YHR041C SRB2 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; general transcription factor involved in telomere maintenance Verified chr8:189124-189857 189124-189742,189844-189857 98.3% 307.03 345.61 307.03 237.91 244.34 122.17 326.32 272.47 183.26 1.20 1.11 0.76 -0.57 -0.93 Matched[2588]
YHR042W NCP1 NADP-cytochrome P450 reductase; involved in ergosterol biosynthesis; associated and coordinately regulated with Erg11p Verified chr8:190536-192611 190536-192611 98.7% 767.43 1115.77 740.11 693.76 233.20 329.32 941.60 716.93 281.26 3.48 2.91 1.17 -1.35 -0.68 Matched[2589]
YHR043C DOG2 "2-deoxyglucose-6-phosphate phosphatase, member of a family of low molecular weight phosphatases, similar to Dog1p, induced by oxidative and osmotic stress, confers 2-deoxyglucose resistance when overexpressed" Verified chr8:192798-193538 192798-193538 53.3% 382.48 430.61 496.46 476.20 1198.10 802.96 406.54 486.33 1000.53 1.50 1.97 4.15 1.04 0.70 Frag<80[2590]
YHR044C DOG1 "2-deoxyglucose-6-phosphate phosphatase, similar to Dog2p, member of a family of low molecular weight phosphatases; confers 2-deoxyglucose resistance when overexpressed, in vivo substrate has not yet been identified" Verified chr8:194061-194801 194061-194801 52.9% 40.78 33.14 35.68 43.33 91.76 43.33 36.96 39.51 67.54 0.14 0.16 0.28 0.77 0.32 Frag<80[2591]
YHR045W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum Uncharacterized chr8:195544-197226 195544-197226 98.8% 202.64 189.41 175.58 160.55 122.67 79.97 196.03 168.07 101.32 0.72 0.68 0.42 -0.73 -0.66 Matched[2592]
YHR046C INM1 "Inositol monophosphatase, involved in biosynthesis of inositol and in phosphoinositide second messenger signaling; INM1 expression increases in the presence of inositol and decreases upon exposure to antibipolar drugs lithium and valproate" Verified chr8:197391-198278 197391-198278 99.2% 233.81 237.22 165.71 107.83 69.24 30.65 235.52 136.77 49.94 0.87 0.56 0.21 -1.45 -1.21 Matched[2593]
YHR047C AAP1 "Arginine/alanine aminopeptidase, overproduction stimulates glycogen accumulation" Verified chr8:198733-201303 198733-201303 98.7% 184.89 223.92 206.57 232.99 187.65 203.03 204.41 219.78 195.34 0.75 0.89 0.81 -0.17 0.34 Frag>80[2594,2595,2596]
YHR048W "Putative protein of unknown function, has similarity to multidrug resistance proteins; expression of gene is up-regulated in cells exhibiting reduced susceptibility to azoles" Uncharacterized chr8:204600-206144 204600-206144 98.8% 51.76 60.28 45.87 34.73 39.97 23.59 56.02 40.30 31.78 0.21 0.16 0.13 -0.34 -0.79 Matched[2599]
YHR049W FSH1 Serine hydrolase that localizes to both the nucleus and cytoplasm; sequence is similar to Fsh2p and Fsh3p Verified chr8:206455-207186 206455-207186 98.8% 773.26 504.90 774.64 633.54 1593.54 1067.90 639.08 704.09 1330.72 2.36 2.86 5.51 0.92 0.93 Matched[2600]
YHR049C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr8:207213-207524 207213-207524 98.6% 162.51 149.51 162.51 159.26 393.28 211.27 156.01 160.89 302.28 0.58 0.65 1.25 0.91 -0.10 Frag<80[2600]
YHR050W SMF2 Divalent metal ion transporter involved in manganese homeostasis; has broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal transport proteins Verified chr8:207648-209297 207648-209297 98.7% 194.00 171.90 203.21 182.34 211.19 150.41 182.95 192.78 180.80 0.68 0.78 0.75 -0.09 0.26 Matched[2601]
YHR050W-A Protein of unknown function; identified by expression profiling and mass spectrometry Uncharacterized chr8:209469-209639 209469-209639 99.2% 282.98 271.19 389.09 383.20 448.05 347.83 277.08 386.15 397.94 1.02 1.57 1.65 0.04 NaN Matched[2602]
YHR051W COX6 "Subunit VI of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; expression is regulated by oxygen levels" Verified chr8:209699-210145 209699-210145 98.6% 746.38 843.94 862.09 1048.11 1901.12 1431.52 795.16 955.10 1666.32 2.94 3.88 6.90 0.80 0.48 Frag>80[2602,2603]
YHR052W CIC1 Essential protein that interacts with proteasome components and has a potential role in proteasome substrate specificity; also copurifies with 66S pre-ribosomal particles Verified chr8:210842-211972 210842-211972 98.8% 399.16 207.64 248.81 239.86 22.37 6.26 303.40 244.33 14.32 1.12 0.99 0.06 -4.09 -3.58 Matched[2604]
YHR052W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps CUP1-1" Dubious chr8:212512-212706 212512-212706 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YHR053C CUP1-1 "Metallothionein, binds copper and mediates resistance to high concentrations of copper and cadmium; locus is variably amplified in different strains, with two copies, CUP1-1 and CUP1-2, in the genomic sequence reference strain S288C" Verified chr8:212537-212722 212537-212722 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.35
YHR054C Putative protein of unknown function Uncharacterized chr8:213187-214251 213187-214251 2.3% 0.00 80.00 200.00 0.00 0.00 40.00 40.00 100.00 20.00 0.15 0.41 0.08 -2.32 0.34 Frag<80[2605]
YHR054W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps CUP1-2" Dubious chr8:214510-214704 214510-214704 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YHR055C CUP1-2 "Metallothionein, binds copper and mediates resistance to high concentrations of copper and cadmium; locus is variably amplified in different strains, with two copies, CUP1-1 and CUP1-2, in the genomic sequence reference strain S288C" Verified chr8:214535-214720 214535-214720 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.36
YHR056W-A "Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr8:217408-217842 217408-217842 98.7% 72.20 79.18 76.86 65.21 39.59 72.20 75.69 71.03 55.90 0.28 0.29 0.23 -0.35 NaN Covered[2606]
YHR056C RSC30 Component of the RSC chromatin remodeling complex; non-essential gene required for regulation of ribosomal protein genes and the cell wall/stress response; highly similar to Rsc3p; null mutants are osmosensitive Verified chr8:215185-217836 215185-217836 60.2% 106.51 116.53 107.76 103.38 79.57 98.36 111.52 105.57 88.97 0.41 0.43 0.37 -0.25 0.34 Frag<80[2606,2607]
YHR057C CPR2 "Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; has a potential role in the secretory pathway" Verified chr8:218228-218845 218228-218845 99.2% 433.84 455.05 428.95 402.85 583.89 494.19 444.44 415.90 539.04 1.64 1.69 2.23 0.37 0.69 Frag>80[2607,2608]
YHR058C MED6 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation Verified chr8:218999-219886 218999-219886 99.2% 68.13 88.57 77.21 69.27 65.86 48.83 78.35 73.24 57.34 0.29 0.30 0.24 -0.35 -0.05 Covered/w/another[2609]
YHR059W FYV4 "Protein of unknown function, required for survival upon exposure to K1 killer toxin" Verified chr8:220110-220502 220110-220502 98.6% 159.95 216.70 208.96 154.79 175.43 95.45 188.33 181.88 135.44 0.70 0.74 0.56 -0.43 -0.14 Covered/w/another[2609]
YHR060W VMA22 "Integral membrane protein that is required for vacuolar H+-ATPase (V-ATPase) function, although not an actual component of the V-ATPase complex; functions in the assembly of the V-ATPase; localized to the yeast endoplasmic reticulum (ER)" Verified chr8:220727-221272 220727-221272 98.4% 269.79 303.28 247.46 223.27 280.95 197.22 286.53 235.37 239.09 1.06 0.96 0.99 0.02 -0.48 Covered/w/another[2609]
YHR061C GIC1 "Protein of unknown function involved in initiation of budding and cellular polarization, interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain" Verified chr8:221536-222480 221536-222480 98.9% 120.88 126.23 86.65 78.09 83.44 85.58 123.55 82.37 84.51 0.46 0.33 0.35 0.04 -0.26 Covered/w/another[2609]
YHR062C RPP1 "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends" Verified chr8:222879-223760 222879-223760 99.1% 112.15 104.14 115.59 89.27 25.18 11.44 108.15 102.43 18.31 0.40 0.42 0.08 -2.48 -1.69 Covered/w/another[2609]
YHR063C PAN5 "2-dehydropantoate 2-reductase, part of the pantothenic acid pathway, structurally homologous to E. coli panE" Verified chr8:224032-225171 224032-225171 99.2% 337.72 339.49 350.98 296.17 242.24 183.00 338.60 323.57 212.62 1.25 1.31 0.88 -0.61 -0.50 Matched[2610]
YHR063W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr8:225444-225779 225444-225779 99.6% 2196.49 1347.78 1855.81 1598.80 851.70 791.93 1772.13 1727.31 821.82 6.54 7.01 3.41 -1.07 NaN Matched[2611]
YHR064C SSZ1 Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) to form a ribosome-associated complex that binds the ribosome via the Zuo1p subunit; also involved in pleiotropic drug resistance via sequential activation of PDR1 and PDR5; binds ATP Verified chr8:225527-227143 225527-227143 98.9% 1723.58 1076.30 1539.09 1500.31 580.99 714.82 1399.94 1519.70 647.90 5.17 6.17 2.68 -1.23 -0.57 Frag>80[2611,2612]
YHR065C RRP3 "Protein involved in rRNA processing; required for maturation of the 35S primary transcript of pre-rRNA and for cleavage leading to mature 18S rRNA; homologous to eIF-4a, which is a DEAD box RNA-dependent ATPase with helicase activity" Verified chr8:227534-229039 227534-229039 99.2% 244.89 185.34 192.03 171.96 24.09 11.37 215.12 182.00 17.73 0.79 0.74 0.07 -3.36 -3.72 Matched[2613]
YHR066W SSF1 "Constituent of 66S pre-ribosomal particles, required for ribosomal large subunit maturation; functionally redundant with Ssf2p; member of the Brix family" Verified chr8:229337-230698 229337-230698 58.4% 237.67 153.42 145.87 101.86 10.06 11.32 195.55 123.87 10.69 0.72 0.50 0.04 -3.53 -3.97 Frag>80[2614,2615,2616]
YHR067W HTD2 "Mitochondrial 3-hydroxyacyl-thioester dehydratase involved in fatty acid biosynthesis, required for respiratory growth and for normal mitochondrial morphology" Verified chr8:230972-231814 230972-231814 98.9% 112.79 93.60 90.00 82.80 157.19 85.20 103.19 86.40 121.19 0.38 0.35 0.50 0.49 0.54 Matched[2617]
YHR068W DYS1 "Deoxyhypusine synthase, catalyzes formation of deoxyhypusine, the first step in hypusine biosynthesis; triggers posttranslational hypusination of translation elongation factor eIF-5A and regulates its intracellular levels; tetrameric" Verified chr8:232135-233298 232135-233298 98.7% 1938.28 1715.47 1561.41 1491.79 732.84 619.69 1826.87 1526.60 676.26 6.74 6.20 2.80 -1.17 -1.04 Matched[2618]
YHR069C RRP4 "3'-5' exoribonuclease involved in rRNA processing; component of the exosome 3->5 exonuclease complex with Rrp41p, Rrp42p, Rrp43p and Dis3p" Verified chr8:233581-234660 233581-234660 99.1% 183.18 174.77 139.25 101.87 75.70 38.32 178.97 120.56 57.01 0.66 0.49 0.24 -1.08 -1.08 Covered/w/another[2619]
YHR070W TRM5 "tRNA(m(1)G37)methyltransferase, methylates a tRNA base adjacent to the anticodon that has a role in prevention of frameshifting; highly conserved across Archaea, Bacteria, and Eukarya" Verified chr8:234883-236382 234883-236382 98.6% 125.72 114.23 93.28 95.31 29.06 24.33 119.98 94.29 26.70 0.44 0.38 0.11 -1.82 -1.73 Covered/w/another[2619]
YHR069C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr8:234876-235238 234876-235238 98.7% 47.45 97.70 69.78 66.99 36.29 25.12 72.58 68.39 30.70 0.27 0.28 0.13 -1.16 NaN Covered/w/another[2619]
YHR070C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene TRM5/YHR070W" Dubious chr8:236104-236514 236104-236514 98.4% 197.88 136.04 133.57 121.20 27.21 27.21 166.96 127.38 27.21 0.62 0.52 0.11 -2.23 NaN Covered/w/another[2619]
YHR071W PCL5 "Cyclin, interacts with Pho85p cyclin-dependent kinase (Cdk), induced by Gcn4p at level of transcription, specifically required for Gcn4p degradation, may be sensor of cellular protein biosynthetic capacity" Verified chr8:237006-237695 237006-237695 98.9% 675.75 1715.02 656.69 712.39 1238.62 1168.26 1195.38 684.54 1203.44 4.41 2.78 4.99 0.81 0.94 Matched[2620]
YHR072W ERG7 "Lanosterol synthase, an essential enzyme that catalyzes the cyclization of squalene 2,3-epoxide, a step in ergosterol biosynthesis" Verified chr8:239100-241295 239100-241295 98.7% 240.79 193.74 208.96 175.75 89.95 74.27 217.27 192.36 82.11 0.80 0.78 0.34 -1.23 -1.12 Covered/w/another[2621]
YHR071C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF ERG7/YHR072W" Dubious chr8:238912-239232 238912-239232 98.9% 66.13 94.48 75.58 69.28 22.04 37.79 80.30 72.43 29.92 0.30 0.29 0.12 -1.28 NaN Covered/w/another[2621]
YHR072W-A NOP10 "Constituent of small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs, which are required for pseudouridylation and processing of pre-18S rRNA" Verified chr8:241666-241842 241666-241842 98.4% 2119.67 1390.14 1545.24 1390.14 350.41 292.96 1754.91 1467.69 321.68 6.48 5.96 1.33 -2.19 -2.56 Matched[2622]
YHR073W OSH3 "Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability" Verified chr8:242584-245574 242584-245574 98.7% 156.82 187.98 141.24 143.61 102.63 108.05 172.40 142.43 105.34 0.64 0.58 0.44 -0.44 0.11 Matched[2623]
YHR073W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF YHR073W; identified by expression profiling and mass spectrometry" Dubious chr8:242870-243046 242870-243046 98.7% 80.17 131.71 34.36 62.99 57.27 68.72 105.94 48.68 62.99 0.39 0.20 0.26 0.37 NaN Covered/w/another[2623]
YHR073C-B "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF YHR073W; identified by expression profiling and mass spectrometry" Dubious chr8:245424-245504 245424-245504 98.1% 314.47 377.36 352.20 264.15 276.73 176.10 345.91 308.18 226.42 1.28 1.25 0.94 -0.44 NaN Covered/w/another[2623]
YHR074W QNS1 "Glutamine-dependent NAD(+) synthetase, essential for the formation of NAD(+) from nicotinic acid adenine dinucleotide" Verified chr8:246195-248339 246195-248339 98.7% 310.22 302.66 316.83 302.19 259.69 225.23 306.44 309.51 242.46 1.13 1.26 1.00 -0.35 0.19 Matched[2624]
YHR075C PPE1 Protein with carboxyl methyl esterase activity that may have a role in demethylation of the phosphoprotein phosphatase catalytic subunit; also identified as a small subunit mitochondrial ribosomal protein Verified chr8:248441-249643 248441-249643 99.1% 99.03 148.54 85.60 79.73 188.82 95.67 123.78 82.66 142.25 0.46 0.34 0.59 0.78 0.33 Matched[2625]
YHR076W PTC7 Mitochondrially localized type 2C protein phosphatase; expression induced by growth on ethanol and by sustained osmotic stress; possible role in carbon source utilization in low oxygen environments Verified chr8:251103-252227 251103-251157,251251-252227 98.6% 251.69 279.22 265.45 264.47 337.23 230.06 265.45 264.96 283.64 0.98 1.08 1.18 0.10 0.07 Matched[2627]
YHR077C NMD2 Protein involved in the nonsense-mediated mRNA decay (NMD) pathway; interacts with Nam7p and Upf3p; involved in telomere maintenance Verified chr8:252376-255758 252376-255639,255753-255758 98.7% 186.23 165.47 149.35 139.75 79.32 83.97 175.85 144.55 81.65 0.65 0.59 0.34 -0.82 -0.38 Matched[2628]
YHR078W High osmolarity-regulated gene of unknown function Uncharacterized chr8:256362-258020 256362-258020 99.1% 172.72 199.48 168.46 135.62 153.26 110.69 186.10 152.04 131.97 0.69 0.62 0.55 -0.20 -0.19 Matched[2629]
YHR079C IRE1 Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; Kar2p binds inactive Ire1p and releases from it upon ER stress Verified chr8:258246-261593 258246-261593 99.1% 81.04 93.70 67.18 56.94 40.67 41.88 87.37 62.06 41.27 0.32 0.25 0.17 -0.59 0.15 Matched[2630]
YHR079C-A SAE3 "Meiosis specific protein involved in DMC1-dependent meiotic recombination, forms heterodimer with Mei5p; proposed to be an assembly factor for Dmc1p" Verified chr8:262194-262555 262194-262356,262443-262555 99.7% 21.81 14.54 3.64 3.64 3.64 32.72 18.18 3.64 18.18 0.07 0.01 0.08 2.32 0.31
YHR080C "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr8:262803-266840 262803-266840 99.1% 91.69 101.19 105.69 102.69 111.18 125.67 96.44 104.19 118.43 0.36 0.42 0.49 0.18 0.90 Covered/w/another[2631]
YHR081W LRP1 Substrate-specific nuclear cofactor for exosome activity in the processing of stable RNAs; required for telomere length maintenance; homolog of mammalian nuclear matrix protein C1D involved in regulation of DNA repair and recombination Verified chr8:267540-268094 267540-268094 98.2% 348.54 176.11 212.80 154.09 115.57 67.87 262.33 183.44 91.72 0.97 0.74 0.38 -1.00 -1.46 Covered/w/another[2631]
YHR082C KSP1 Nonessential putative serine/threonine protein kinase of unknown cellular role; overproduction causes allele-specific suppression of the prp20-10 mutation Verified chr8:268461-271550 268461-271550 99.2% 309.36 339.06 317.19 331.23 668.33 995.31 324.21 324.21 831.82 1.20 1.32 3.45 1.36 1.83 Covered/w/another[2632]
YHR083W SAM35 "Essential component of the sorting and assembly machinery (SAM complex or TOB complex) of the mitochondrial outer membrane, which binds precursors of beta-barrel proteins and facilitates their insertion into the outer membrane" Verified chr8:272629-273618 272629-273618 98.7% 315.34 352.20 311.25 316.37 293.84 302.03 333.77 313.81 297.94 1.23 1.27 1.23 -0.07 0.29 Covered/w/another[2632]
YHR084W STE12 "Transcription factor that is activated by a MAP kinase signaling cascade, activates genes involved in mating or pseudohyphal/invasive growth pathways; cooperates with Tec1p transcription factor to regulate genes specific for invasive growth" Verified chr8:274176-276242 274176-276242 98.9% 350.63 382.42 331.07 337.92 70.91 99.27 366.53 334.49 85.09 1.35 1.36 0.35 -1.97 -1.47 Matched[2633]
YHR085W IPI1 Essential component of the Rix1 complex (with Rix1p and Ipi3p) that is required for processing of ITS2 sequences from 35S pre-rRNA; Rix1 complex associates with Mdn1p in pre-60S ribosomal particles Verified chr8:276766-277770 276766-277770 98.6% 130.14 65.58 63.56 47.42 15.13 18.16 97.86 55.49 16.65 0.36 0.23 0.07 -1.74 -2.89 Matched[2634]
YHR086W NAM8 "RNA binding protein, component of the U1 snRNP protein; mutants are defective in meiotic recombination and in formation of viable spores, involved in the formation of DSBs through meiosis-specific splicing of MER2 pre-mRNA" Verified chr8:278155-279726 278155-279726 98.8% 140.97 157.71 174.44 188.61 242.68 216.29 149.34 181.53 229.48 0.55 0.74 0.95 0.34 0.45 Frag>80[2635,2636]
YHR086W-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr8:280233-280394 280233-280394 99.1% 0.00 0.00 0.00 6.23 0.00 0.00 0.00 3.11 0.00 0.00 0.01 0.00 -Inf NaN
YHR087W "Protein of unknown function involved in RNA metabolism; this single domain protein has structural similarity to the N-terminal domain of SBDS, the human protein mutated in Shwachman-Diamond Syndrome (the yeast SBDS ortholog = SDO1/YLR022C)" Verified chr8:280822-281157 280822-281157 98.3% 181.75 757.29 402.88 396.82 17684.21 11032.19 469.52 399.85 14358.20 1.73 1.62 59.49 5.17 4.26 Frag>80[2637,2638]
YHR088W RPF1 "Nucleolar protein involved in the assembly of the large ribosomal subunit; constituent of 66S pre-ribosomal particles; contains a sigma(70)-like motif, which is thought to bind RNA" Verified chr8:281497-282384 281497-282384 98.5% 250.48 130.39 144.11 97.22 19.44 21.73 190.43 120.66 20.59 0.70 0.49 0.09 -2.55 -3.66 Matched[2639]
YHR089C GAR1 "Protein component of the H/ACA snoRNP pseudouridylase complex, involved in the modification and cleavage of the 18S pre-rRNA" Verified chr8:282683-283300 282683-283300 97.7% 2021.12 1232.55 1590.39 1394.91 142.47 57.98 1626.84 1492.65 100.23 6.01 6.06 0.42 -3.90 -3.15 Covered/w/another[2640]
YHR090C YNG2 Subunit of the NuA4 histone acetyltransferase complex that acetylates histone H4 and H2A; has similarity to the human tumor suppressor ING1 Verified chr8:283779-284627 283779-284627 99.2% 111.58 105.64 130.57 78.34 132.94 115.14 108.61 104.46 124.04 0.40 0.42 0.51 0.25 0.30 Covered/w/another[2640]
YHR091C MSR1 Mitochondrial arginyl-tRNA synthetase Verified chr8:284841-286772 284841-286772 99.0% 82.57 93.55 98.25 76.30 81.53 52.79 88.06 87.28 67.16 0.33 0.35 0.28 -0.38 0.17 Covered/w/another[2640]
YHR092C HXT4 "High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose" Verified chr8:287132-288814 287132-288814 83.0% 1263.20 1764.18 2401.15 3079.62 277.69 191.81 1513.69 2740.38 234.75 5.59 11.12 0.97 -3.55 -2.53 Matched[2641]
YHR093W AHT1 "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; multicopy suppressor of glucose transport defects, likely due to the presence of an HXT4 regulatory element in the region" Dubious chr8:289145-289693 289145-289693 98.3% 1.85 1.85 11.12 5.56 7.41 1.85 1.85 8.34 4.63 0.01 0.03 0.02 -0.85 -0.58
YHR094C HXT1 "Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting" Verified chr8:290916-292628 290916-292628 82.8% 45.11 9.87 11.28 6.34 11.28 2.82 27.49 8.81 7.05 0.10 0.04 0.03 -0.32 -2.32 Frag<80[2642]
YHR095W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr8:292946-293380 292946-293380 97.5% 11.79 0.00 7.07 4.72 0.00 9.43 5.90 5.90 4.72 0.02 0.02 0.02 -0.32 -0.12
YHR096C HXT5 "Hexose transporter with moderate affinity for glucose, induced in the presence of non-fermentable carbon sources, induced by a decrease in growth rate, contains an extended N-terminal domain relative to other HXTs" Verified chr8:294672-296450 294672-296450 92.3% 20.09 28.01 33.49 24.35 389.06 208.23 24.05 28.92 298.65 0.09 0.12 1.24 3.37 3.44 Frag>80[2643,2644]
YHR097C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus Uncharacterized chr8:297388-298612 297388-298363,298488-298612 98.9% 167.99 214.80 310.27 253.36 813.31 684.80 191.39 281.81 749.05 0.71 1.14 3.10 1.41 1.72 Frag>80[2645,2646]
YHR098C SFB3 "Member of the Sec24p family; forms a complex, with Sec23p, that is involved in sorting of Pma1p into COPII vesicles; peripheral ER membrane protein; potential Cdc28p substrate" Verified chr8:299148-301937 299148-301937 99.0% 291.80 293.25 303.03 276.96 200.21 257.77 292.53 289.99 228.99 1.08 1.18 0.95 -0.34 0.26 Matched[2647]
YHR099W TRA1 "Subunit of SAGA and NuA4 histone acetyltransferase complexes; interacts with acidic activators (e.g., Gal4p) which leads to transcription activation; similar to human TRRAP, which is a cofactor for c-Myc mediated oncogenic transformation" Verified chr8:302764-313998 302764-313998 99.0% 69.96 57.46 56.47 48.38 19.51 39.11 63.71 52.42 29.31 0.24 0.21 0.12 -0.84 -0.32 Frag<80[2648]
YHR100C "Putative protein of unknown function, required for respiratory growth; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr8:314119-314676 314119-314676 98.8% 126.95 90.68 116.06 96.12 70.73 61.66 108.81 106.09 66.19 0.40 0.43 0.27 -0.68 -1.05 Covered/w/another[2649]
YHR101C BIG1 "Integral membrane protein of the endoplasmic reticulum, required for normal content of cell wall beta-1,6-glucan" Verified chr8:314877-315971 314877-315774,315862-315971 99.2% 60.01 71.01 47.00 47.00 64.01 40.00 65.51 47.00 52.00 0.24 0.19 0.22 0.15 0.76 Covered/w/another[2649]
YHR102W KIC1 "Protein kinase of the PAK/Ste20 kinase family, required for cell integrity possibly through regulating 1,6-beta-glucan levels in the wall; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body" Verified chr8:316575-319817 316575-319817 98.8% 91.14 94.89 80.84 75.22 68.04 66.48 93.01 78.03 67.26 0.34 0.32 0.28 -0.21 0.35 Matched[2650]
YHR103W SBE22 Protein involved in the transport of cell wall components from the Golgi to the cell surface; similar in structure and functionally redundant with Sbe2p; involved in bud growth Verified chr8:320417-322975 320417-322975 98.8% 215.27 203.40 180.05 166.99 235.05 192.32 209.33 173.52 213.69 0.77 0.70 0.89 0.30 0.53 Matched[2651]
YHR104W GRE3 "Aldose reductase involved in methylglyoxal, d-xylose and arabinose metabolism; stress induced (osmotic, ionic, oxidative, heat shock, starvation and heavy metals); regulated by the HOG pathway" Verified chr8:323412-324395 323412-324395 98.8% 362.03 519.39 503.96 457.68 7925.60 6205.96 440.71 480.82 7065.78 1.63 1.95 29.28 3.88 3.67 Matched[2653]
YHR105W YPT35 Endosomal protein of unknown function that contains a phox (PX) homology domain and binds to both phosphatidylinositol-3-phosphate (PtdIns(3)P) and proteins involved in ER-Golgi or vesicular transport Verified chr8:324769-325413 324769-325413 98.6% 39.30 64.46 44.02 47.16 67.60 45.59 51.88 45.59 56.60 0.19 0.19 0.23 0.31 0.96 Covered/w/another[2654]
YHR106W TRR2 "Mitochondrial thioredoxin reductase involved in protection against oxidative stress, required with Glr1p to maintain the redox state of Trx3p; contains active-site motif (CAVC) present in prokaryotic orthologs; binds NADPH and FAD" Verified chr8:325601-326629 325601-326629 97.7% 122.41 187.10 139.33 126.39 244.82 178.14 154.75 132.86 211.48 0.57 0.54 0.88 0.67 0.59 Covered/w/another[2654]
YHR107C CDC12 "Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM" Verified chr8:326816-328039 326816-328039 99.1% 347.23 282.07 366.20 316.71 278.77 268.05 314.65 341.46 273.41 1.16 1.39 1.13 -0.32 0.13 Matched[2655]
YHR108W GGA2 "Golgi-localized protein with homology to gamma-adaptin, interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner in order to facilitate traffic through the late Golgi" Verified chr8:328306-330063 328306-330063 98.9% 466.40 471.01 496.88 479.63 428.45 370.36 468.71 488.26 399.41 1.73 1.98 1.65 -0.29 0.17 Matched[2656]
YHR109W CTM1 "Cytochrome c lysine methyltransferase, trimethylates residue 72 of apo-cytochrome c (Cyc1p) in the cytosol; not required for normal respiratory growth" Verified chr8:330313-332070 330313-332070 99.0% 44.83 43.11 46.56 36.21 40.81 36.79 43.97 41.38 38.80 0.16 0.17 0.16 -0.09 0.50 Matched[2657]
YHR110W ERP5 "Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport" Verified chr8:332285-332923 332285-332923 98.6% 438.01 471.34 458.64 449.12 542.75 426.90 454.67 453.88 484.82 1.68 1.84 2.01 0.10 0.19 Matched[2658]
YHR111W UBA4 "Protein that activates Urm1p before its conjugation to proteins (urmylation); one target is the thioredoxin peroxidase Ahp1p, suggesting a role of urmylation in the oxidative stress response" Verified chr8:333075-334397 333075-334397 98.6% 125.71 128.78 113.45 111.15 105.78 60.56 127.25 112.30 83.17 0.47 0.46 0.34 -0.43 0.10 Matched[2659]
YHR112C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr8:334530-335666 334530-335666 98.8% 209.10 364.81 185.07 223.33 389.72 337.23 286.95 204.20 363.47 1.06 0.83 1.51 0.83 1.04 Matched[2660]
YHR113W Cytoplasmic aspartyl aminopeptidase; cleaves unblocked N-terminal acidic amino acid residues from peptide substrates; forms a 12 subunit homo-oligomeric complex; M18 metalloprotease family member; may interact with ribosomes Verified chr8:336340-337812 336340-337812 98.7% 301.95 361.79 321.90 351.47 480.78 416.82 331.87 336.69 448.80 1.23 1.37 1.86 0.41 0.93 Matched[2661]
YHR114W BZZ1 "SH3 domain protein implicated in the regulation of actin polymerization, able to recruit actin polymerization machinery through its SH3 domains, colocalizes with cortical actin patches and Las17p, interacts with type I myosins" Verified chr8:338086-339987 338086-339987 98.5% 199.55 169.67 197.42 191.55 208.09 237.97 184.61 194.48 223.03 0.68 0.79 0.92 0.20 0.77 Matched[2662]
YHR115C DMA1 "Protein involved in regulating spindle position and orientation, functionally redundant with Dma2p; homolog of S. pombe Dma1 and H. sapiens Chfr" Verified chr8:340112-341362 340112-341362 98.6% 187.22 172.63 173.44 136.16 278.80 140.21 179.92 154.80 209.50 0.66 0.63 0.87 0.44 0.75 Matched[2663]
YHR116W COX23 "Mitochondrial intermembrane space protein that functions in mitochondrial copper homeostasis, essential for functional cytochrome oxidase expression; homologous to Cox17p" Verified chr8:341668-342123 341668-342123 98.4% 111.47 122.62 138.23 95.87 236.32 111.47 117.05 117.05 173.90 0.43 0.48 0.72 0.57 0.35 Covered/w/another[2664]
YHR117W TOM71 Mitochondrial outer membrane protein with similarity to Tom70p; probable minor component of the TOM (translocase of outer membrane) complex responsible for recognition and import of mitochondrially directed proteins Verified chr8:342352-344271 342352-344271 98.7% 261.32 216.97 236.51 236.51 146.76 150.98 239.14 236.51 148.87 0.88 0.96 0.62 -0.67 -0.13 Matched[2664]
YHR118C ORC6 "Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; phosphorylated by Cdc28p" Verified chr8:344324-345631 344324-345631 99.4% 83.03 79.95 66.12 75.34 49.20 43.05 81.49 70.73 46.13 0.30 0.29 0.19 -0.62 -0.16
YHR119W SET1 "Histone methyltransferase, subunit of the COMPASS (Set1C) complex which methylates histone H3 on lysine 4; required in transcriptional silencing near telomeres and at the silent mating type loci; contains a SET domain" Verified chr8:346046-349288 346046-349288 98.7% 123.68 114.31 110.87 76.83 61.84 55.90 118.99 93.85 58.87 0.44 0.38 0.24 -0.67 -0.08 Covered/w/another[2665]
YHR120W MSH1 "DNA-binding protein of the mitochondria involved in repair of mitochondrial DNA, has ATPase activity and binds to DNA mismatches; has homology to E. coli MutS; transcription is induced during meiosis" Verified chr8:349577-352456 349577-352456 98.7% 42.56 44.67 42.56 29.20 22.16 18.29 43.62 35.88 20.23 0.16 0.15 0.08 -0.83 -0.15 Frag<80[2666]
YHR121W LSM12 Protein of unknown function that may function in RNA processing; interacts with Pbp1p and Pbp4p and associates with ribosomes; contains an RNA-binding LSM domain and an AD domain; GFP-fusion protein is induced by the DNA-damaging agent MMS Verified chr8:352759-353322 352759-353322 98.5% 473.48 531.09 439.28 446.48 468.08 293.45 502.29 442.88 380.77 1.85 1.80 1.58 -0.22 -0.59 Matched[2667]
YHR122W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; may be involved in transcription; YHR122W is an essential gene Uncharacterized chr8:353628-354323 353628-354323 98.4% 126.98 132.81 106.54 102.16 96.33 56.92 129.90 104.35 76.62 0.48 0.42 0.32 -0.45 -0.71 Frag>80[2668,2669]
YHR123W EPT1 "sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase; not essential for viability" Verified chr8:354818-356084 354818-354867,354959-356084 99.2% 145.77 194.65 154.35 133.77 189.50 130.34 170.21 144.06 159.92 0.63 0.58 0.66 0.15 0.74 Matched[2670]
YHR124W NDT80 Meiosis-specific transcription factor required for exit from pachytene and for full meiotic recombination; activates middle sporulation genes; competes with Sum1p for binding to promoters containing middle sporulation elements (MSE) Verified chr8:356564-358447 356564-358447 98.8% 30.64 31.71 26.87 17.74 36.55 15.59 31.17 22.31 26.07 0.12 0.09 0.11 0.22 -0.07
YHR125W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr8:358861-359166 358861-359166 99.5% 3.29 3.29 3.29 0.00 0.00 3.29 3.29 1.64 1.64 0.01 0.01 0.01 0.00 0.01
YHR126C Putative protein of unknown function; transcription dependent upon Azf1p Uncharacterized chr8:359705-360184 359705-360184 98.8% 6.32 8.43 0.00 4.22 0.00 8.43 7.38 2.11 4.22 0.03 0.01 0.02 1.00 -0.45
YHR127W Protein of unknown function; localizes to the nucleus Verified chr8:360916-361647 360916-361647 98.3% 232.07 202.88 172.31 163.97 68.09 43.08 217.47 168.14 55.58 0.80 0.68 0.23 -1.60 -1.22 Matched[2671]
YHR128W FUR1 "Uracil phosphoribosyltransferase, synthesizes UMP from uracil; involved in the pyrimidine salvage pathway" Verified chr8:362118-362768 362118-362768 98.7% 756.67 532.47 629.00 569.83 99.64 96.53 644.57 599.42 98.09 2.38 2.43 0.41 -2.61 -2.11 Matched[2672]
YHR129C ARP1 Actin-related protein of the dynactin complex; required for spindle orientation and nuclear migration; putative ortholog of mammalian centractin Verified chr8:363002-364156 363002-364156 99.3% 74.98 81.09 86.32 54.06 45.34 31.39 78.04 70.19 38.36 0.29 0.28 0.16 -0.87 -0.64 Matched[2673]
YHR130C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr8:364968-365303 364968-365303 99.2% 114.01 69.01 72.01 57.01 102.01 51.01 91.51 64.51 76.51 0.34 0.26 0.32 0.25 -0.09 Frag<80[2674]
YHR131W-A Dubious open reading frame unlikely to encode a protein; partially overlaps the uncharacterized ORF YHR131C Dubious chr8:367750-367995 367750-367995 99.2% 61.48 53.28 53.28 32.79 20.49 45.08 57.38 43.03 32.79 0.21 0.17 0.14 -0.39 NaN Covered/w/another[2675]
YHR131C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr8:365343-367895 365343-367895 97.8% 82.06 111.69 78.86 56.84 64.85 76.46 96.87 67.85 70.65 0.36 0.28 0.29 0.06 0.46 Matched[2675]
YHR132C ECM14 "Putative metalloprotease with similarity to the zinc carboxypeptidase family, required for normal cell wall assembly" Verified chr8:368505-369797 368505-369797 99.0% 344.43 327.25 384.26 356.93 335.84 286.63 335.84 370.59 311.24 1.24 1.50 1.29 -0.25 0.18 Matched[2676]
YHR132W-A Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus Uncharacterized chr8:370057-370452 370057-370452 98.5% 399.83 361.38 463.90 399.83 581.80 335.75 380.61 431.87 458.78 1.40 1.75 1.90 0.09 -0.38 Covered/w/another[2677]
YHR133C NSG1 "Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; homolog of mammalian INSIG proteins" Verified chr8:370725-371600 370725-371600 98.9% 529.69 508.92 503.15 512.38 255.04 231.96 519.31 507.77 243.50 1.92 2.06 1.01 -1.06 -0.82 Covered/w/another[2677]
YHR134W WSS1 "Sumoylated protein of unknown function, identified based on genetic interactions with SMT3; UV-sensitive mutant phenotype and genetic interactions suggest a role in the DNA damage response, processing stalled or collapsed replication forks" Verified chr8:371752-372561 371752-372561 98.4% 95.39 138.06 106.68 80.33 91.62 70.29 116.72 93.50 80.95 0.43 0.38 0.34 -0.21 -0.05 Covered/w/another[2677]
YHR135C YCK1 "Palmitoylated, plasma membrane-bound casein kinase I isoform; shares redundant functions with Yck2p in morphogenesis, proper septin assembly, endocytic trafficking; provides an essential function overlapping with that of Yck2p" Verified chr8:372697-374313 372697-374313 98.5% 466.54 413.79 448.96 474.70 325.89 327.77 440.17 461.83 326.83 1.62 1.87 1.35 -0.50 -0.02 Covered/w/another[2677]
YHR136C SPL2 "Protein with similarity to cyclin-dependent kinase inhibitors, overproduction suppresses a plc1 null mutation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" Verified chr8:374657-375103 374657-375103 99.0% 754.52 806.48 860.69 652.86 641.57 307.23 780.50 756.78 474.40 2.88 3.07 1.97 -0.67 -0.72 Covered/w/another[2677]
YHR137W ARO9 "Aromatic aminotransferase II, catalyzes the first step of tryptophan, phenylalanine, and tyrosine catabolism" Verified chr8:375712-377253 375712-377253 98.9% 277.51 404.12 383.78 408.06 3891.64 3453.41 340.81 395.92 3672.53 1.26 1.61 15.22 3.21 2.68 Matched[2679]
YHR137C-A "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps verified gene ARO9/YHR137W; identified by gene-trapping, expression analysis, and genome-wide homology searching" Dubious chr8:375741-376391 375741-376391 98.8% 208.38 360.79 297.03 353.01 2656.13 2834.96 284.58 325.02 2745.55 1.05 1.32 11.38 3.08 NaN Covered/w/another[2679]
YHR138C Putative protein of unknown function; has similarity to Pbi2p; double null mutant lacking Pbi2p and Yhr138p exhibits highly fragmented vacuoles Uncharacterized chr8:377358-377702 377358-377702 99.3% 169.24 157.57 177.99 137.14 1170.09 496.05 163.40 157.57 833.07 0.60 0.64 3.45 2.40 1.86 Matched[2680]
YHR139C SPS100 Protein required for spore wall maturation; expressed during sporulation; may be a component of the spore wall Verified chr8:378222-379202 378222-379202 98.6% 17.57 34.10 9.30 15.50 69.24 66.14 25.84 12.40 67.69 0.10 0.05 0.28 2.45 1.81 Covered/w/another[2681]
YHR139C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr8:380111-380422 380111-380422 99.1% 9.70 12.94 16.17 35.57 100.26 64.68 11.32 25.87 82.47 0.04 0.11 0.34 1.67 1.46 Covered/w/another[2681]
YHR140W Putative integral membrane protein of unknown function Uncharacterized chr8:380575-381294 380575-381294 99.1% 40.66 61.69 58.89 44.87 259.39 172.46 51.18 51.88 215.93 0.19 0.21 0.89 2.06 2.37 Matched[2682]
YHR141C RPL42B "Protein component of the large (60S) ribosomal subunit, identical to Rpl42Ap and has similarity to rat L44; required for propagation of the killer toxin-encoding M1 double-stranded RNA satellite of the L-A double-stranded RNA virus" Verified chr8:381993-382754 381993-382309,382751-382754 30.9% 7892.35 6015.14 7095.04 5591.25 1735.91 1634.99 6953.74 6343.15 1685.45 25.67 25.75 6.98 -1.91 -4.04 Matched[2684]
YHR142W CHS7 "Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p export from the ER" Verified chr8:383541-384491 383541-384491 99.0% 351.54 333.48 335.60 268.70 204.97 156.12 342.51 302.15 180.55 1.26 1.23 0.75 -0.74 -0.47 Matched[2685]
YHR143W DSE2 "Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP" Verified chr8:385513-386490 385513-386490 99.4% 1459.22 1525.08 1340.88 1172.11 599.95 482.63 1492.15 1256.50 541.29 5.51 5.10 2.24 -1.21 -0.57 Frag>80[2687,2688,2689]
YHR143W-A RPC10 "RNA polymerase subunit, found in RNA polymerase complexes I, II, and III" Verified chr8:387236-387448 387236-387448 98.5% 852.89 552.71 762.36 609.89 262.06 214.41 702.80 686.12 238.24 2.59 2.79 0.99 -1.53 -1.98 Matched[2690]
YHR144C DCD1 Deoxycytidine monophosphate (dCMP) deaminase required for dCTP and dTTP synthesis; expression is NOT cell cycle regulated Verified chr8:387791-388729 387791-388729 99.3% 152.33 129.81 141.61 102.99 47.20 36.47 141.07 122.30 41.84 0.52 0.50 0.17 -1.55 -1.40 Matched[2691]
YHR145C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr8:388984-389340 388984-389340 53.1% 0.00 5.27 0.00 0.00 0.00 5.27 2.64 0.00 2.64 0.01 0.00 0.01 Inf 0.38
YHR146W CRP1 Protein that binds to cruciform DNA structures Verified chr8:390303-391700 390303-391700 98.3% 713.38 842.22 599.09 541.58 773.07 805.10 777.80 570.34 789.08 2.87 2.32 3.27 0.47 1.09 Matched[2692]
YHR147C MRPL6 Mitochondrial ribosomal protein of the large subunit Verified chr8:392642-393286 392642-393286 99.0% 342.86 347.55 411.74 382.00 515.07 327.20 345.21 396.87 421.14 1.27 1.61 1.74 0.09 -0.33 Matched[2695]
YHR148W IMP3 "Component of the SSU processome, which is required for pre-18S rRNA processing, essential protein that interacts with Mpp10p and mediates interactions of Imp4p and Mpp10p with U3 snoRNA" Verified chr8:393537-394088 393537-394088 98.9% 139.15 87.89 95.21 71.41 7.32 10.99 113.52 83.31 9.15 0.42 0.34 0.04 -3.19 -3.76 Covered/w/another[2696]
YHR149C SKG6 Integral membrane protein that localizes primarily to growing sites such as the bud tip or the cell periphery; potential Cdc28p substrate; Skg6p interacts with Zds1p and Zds2p Verified chr8:394458-396662 394458-396662 99.0% 160.76 139.23 115.87 88.85 17.40 21.53 149.99 102.36 19.46 0.55 0.42 0.08 -2.39 -1.95 Covered/w/another[2696]
YHR150W PEX28 "Peroxisomal integral membrane peroxin, involved in the regulation of peroxisomal size, number and distribution; genetic interactions suggest that Pex28p and Pex29p act at steps upstream of those mediated by Pex30p, Pex31p, and Pex32p" Verified chr8:397254-398993 397254-398993 98.8% 68.67 58.19 55.87 54.70 60.52 41.32 63.43 55.28 50.92 0.23 0.22 0.21 -0.12 0.23 Covered/w/another[2697]
YHR151C Putative protein of unknown function Uncharacterized chr8:399271-400851 399271-400851 98.9% 67.13 95.91 74.17 54.99 70.33 53.71 81.52 64.58 62.02 0.30 0.26 0.26 -0.06 0.03 Covered/w/another[2697]
YHR152W SPO12 "Nucleolar protein of unknown function, positive regulator of exit from mitosis; involved in regulating the release of Cdc14p from the nucleolus in early anaphase; proposed to play similar role in meiosis" Verified chr8:401437-401958 401437-401958 98.6% 412.02 474.21 400.36 464.49 757.96 464.49 443.11 432.42 611.22 1.64 1.76 2.53 0.50 0.55 Matched[2698]
YHR153C SPO16 "Protein of unknown function, required for spore formation" Verified chr8:402089-402685 402089-402685 99.3% 42.17 52.29 37.11 32.05 32.05 21.93 47.23 34.58 26.99 0.17 0.14 0.11 -0.36 -0.95 Matched[2699]
YHR154W RTT107 "Protein implicated in Mms22-dependent DNA repair during S phase, DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition" Verified chr8:402969-406181 402969-406181 98.9% 199.27 156.46 150.48 116.48 41.87 25.81 177.87 133.48 33.84 0.66 0.54 0.14 -1.98 -1.40 Matched[2700]
YHR155W YSP1 Mitochondrial protein with a potential role in promoting mitochondrial fragmentation during programmed cell death in response to high levels of alpha-factor mating pheromone or the drug amiodarone Verified chr8:407106-410792 407106-410792 99.0% 81.12 73.45 56.46 52.34 59.20 61.66 77.28 54.40 60.43 0.29 0.22 0.25 0.15 0.70 Covered/w/another[2702]
YHR156C LIN1 "Non-essential component of U5 snRNP; nuclear protein; physically interacts with Irr1p of cohesin complex; may link together proteins involved in chromosome segregation, mRNA splicing and DNA replication" Verified chr8:411387-412409 411387-412409 99.5% 52.04 50.08 35.35 49.10 121.76 89.36 51.06 42.22 105.56 0.19 0.17 0.44 1.32 1.42 Covered/w/another[2702]
YHR157W REC104 Protein involved in early stages of meiotic recombination; required for meiotic crossing over; forms a complex with Rec102p and Spo11p necessary during the initiation of recombination Verified chr8:412910-413458 412910-413458 98.8% 12.90 7.37 9.21 9.21 36.86 23.96 10.14 9.21 30.41 0.04 0.04 0.13 1.72 0.39 Covered/w/another[2702]
YHR158C KEL1 "Protein required for proper cell fusion and cell morphology; functions in a complex with Kel2p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate" Verified chr8:413688-417182 413688-417182 99.1% 162.34 157.43 152.80 139.52 105.72 132.87 159.88 146.16 119.30 0.59 0.59 0.49 -0.29 0.26 Matched[2703]
YHR159W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; potential Cdc28p substrate Uncharacterized chr8:417552-419066 417552-419066 98.5% 63.00 66.35 56.97 63.00 107.23 93.16 64.67 59.98 100.20 0.24 0.24 0.42 0.74 0.95 Matched[2704]
YHR160C PEX18 Peroxin required for targeting of peroxisomal matrix proteins containing PTS2; interacts with Pex7p; partially redundant with Pex21p Verified chr8:419224-420075 419224-420075 99.4% 46.07 50.80 34.26 22.45 79.15 54.34 48.43 28.35 66.75 0.18 0.12 0.28 1.24 2.26 Matched[2705]
YHR161C YAP1801 "Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1802p, member of the AP180 protein family" Verified chr8:420376-422289 420376-422289 97.7% 170.51 204.19 189.22 179.06 491.76 343.16 187.35 184.14 417.46 0.69 0.75 1.73 1.18 1.59 Frag>80[2706,2707]
YHR162W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion Uncharacterized chr8:423075-423464 423075-423464 98.5% 2090.47 2551.25 2199.80 1931.66 3852.91 1910.84 2320.86 2065.73 2881.87 8.57 8.39 11.94 0.48 -0.57 Matched[2708]
YHR163W SOL3 "6-phosphogluconolactonase, catalyzes the second step of the pentose phosphate pathway; weak multicopy suppressor of los1-1 mutation; homologous to Sol2p and Sol1p" Verified chr8:423726-424475 423726-424475 98.7% 517.31 482.19 517.31 428.16 783.39 653.72 499.75 472.73 718.55 1.84 1.92 2.98 0.60 0.57 Matched[2709]
YHR164C DNA2 "Essential tripartite DNA replication factor with single-stranded DNA-dependent ATPase, ATP-dependent nuclease, and helicase activities; required for Okazaki fragment processing; involved in DNA repair pathways; potential Cdc28p substrate" Verified chr8:424612-429180 424612-429180 99.2% 47.43 54.05 39.93 31.11 50.74 48.09 50.74 35.52 49.42 0.19 0.14 0.20 0.48 0.39 Matched[2710]
YHR165W-A "Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr8:436649-436960 436649-436960 98.4% 32.59 65.17 42.36 39.10 48.88 87.98 48.88 40.73 68.43 0.18 0.17 0.28 0.75 NaN Covered/w/another[2711]
YHR165C PRP8 "Component of the U4/U6-U5 snRNP complex, involved in the second catalytic step of splicing; mutations of human Prp8 cause retinitis pigmentosa" Verified chr8:429709-436950 429709-436950 99.1% 93.91 91.68 79.42 72.87 48.49 78.59 92.80 76.15 63.54 0.34 0.31 0.26 -0.26 -0.06 Covered/w/another[2711]
YHR166C CDC23 "Subunit of the anaphase-promoting complex/cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" Verified chr8:437172-439052 437172-439052 99.3% 54.62 65.33 41.77 44.45 53.55 28.38 59.98 43.11 40.97 0.22 0.17 0.17 -0.07 -0.11 Covered/w/another[2711]
YHR167W THP2 "Subunit of the THO complex, which connects transcription elongation and mitotic recombination, and of the TREX complex, which is recruited to activated genes and couples transcription to mRNA export; involved in telomere maintenance" Verified chr8:439344-440129 439344-440129 98.7% 107.03 110.90 92.84 69.63 92.84 54.16 108.96 81.24 73.50 0.40 0.33 0.30 -0.14 -1.22 Covered/w/another[2712]
YHR168W MTG2 "Putative GTPase, member of the Obg family; peripheral protein of the mitochondrial inner membrane that associates with the large ribosomal subunit; required for mitochondrial translation, possibly via a role in ribosome assembly" Verified chr8:440379-441878 440379-441878 98.4% 48.10 66.39 69.78 55.55 69.78 44.03 57.24 62.66 56.90 0.21 0.25 0.24 -0.14 0.40 Covered/w/another[2712]
YHR169W DBP8 Putative ATP-dependent RNA helicase of the DEAD-box family involved in biogenesis of the 40S ribosomal subunit Verified chr8:442182-443477 442182-443477 98.4% 136.42 81.54 55.66 48.61 19.60 11.76 108.98 52.14 15.68 0.40 0.21 0.06 -1.73 -0.20 Matched[2713]
YHR170W NMD3 Protein involved in nuclear export of the large ribosomal subunit; acts as a Crm1p-dependent adapter protein for export of nascent ribosomal subunits through the nuclear pore complex Verified chr8:443829-445385 443829-445385 98.7% 389.59 184.07 232.20 184.72 24.07 5.85 286.83 208.46 14.96 1.06 0.85 0.06 -3.80 -4.38 Matched[2714]
YHR171W ATG7 "Autophagy-related protein and dual specificity member of the E1 family of ubiquitin-activating enzymes; mediates the conjugation of Atg12p with Atg5p and Atg8p with phosphatidylethanolamine, required steps in autophagosome formation" Verified chr8:445713-447605 445713-447605 98.9% 40.59 41.13 55.55 50.21 133.00 91.87 40.86 52.88 112.43 0.15 0.21 0.47 1.09 1.45 Frag>80[2715,2716]
YHR172W SPC97 Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque Verified chr8:448335-450806 448335-450806 98.9% 63.82 60.96 51.96 42.55 40.09 28.64 62.39 47.25 34.36 0.23 0.19 0.14 -0.46 -0.06 Matched[2717]
YHR173C "Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr8:450815-451153 450815-451153 99.3% 139.57 65.33 115.81 98.00 65.33 44.54 102.45 106.90 54.94 0.38 0.43 0.23 -0.96 0.20 Covered/w/another[2717]
YHR174W ENO2 "Enolase II, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; expression is induced in response to glucose" Verified chr8:451327-452640 451327-452640 43.0% 44340.21 40917.45 42035.38 37383.25 32140.33 28758.25 42628.83 39709.32 30449.29 157.36 161.19 126.16 -0.38 -1.36 Matched[2718]
YHR175W CTR2 "Putative low-affinity copper transporter of the vacuolar membrane; mutation confers resistance to toxic copper concentrations, while overexpression confers resistance to copper starvation" Verified chr8:452872-453441 452872-453441 98.8% 374.67 305.42 399.53 324.95 257.47 163.36 340.04 362.24 210.42 1.26 1.47 0.87 -0.78 -0.94 Matched[2719]
YHR175W-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr8:453558-453707 453558-453707 99.7% 207.30 167.18 227.36 180.55 140.43 53.50 187.24 203.96 96.96 0.69 0.83 0.40 -1.07 NaN Matched[2719]
YHR176W FMO1 "Flavin-containing monooxygenase, localized to the cytoplasmic face of the ER membrane; catalyzes oxidation of biological thiols to maintain the ER redox buffer ratio for correct folding of disulfide-bonded proteins" Verified chr8:454229-455527 454229-455527 98.7% 50.71 49.93 50.71 46.02 73.33 42.90 50.32 48.37 58.12 0.19 0.20 0.24 0.26 0.18 Frag>80[2720,2721]
YHR177W Putative protein of unknown function Uncharacterized chr8:456591-457952 456591-457952 98.9% 35.62 28.20 34.14 34.88 34.88 49.72 31.91 34.51 42.30 0.12 0.14 0.18 0.29 1.36 Covered[2722]
YHR178W STB5 "Activator of multidrug resistance genes, forms a heterodimer with Pdr1p; contains a Zn(II)2Cys6 zinc finger domain that interacts with a PDRE (pleotropic drug resistance element) in vitro; binds Sin3p in a two-hybrid assay" Verified chr8:459299-461530 459299-461530 98.8% 55.35 53.08 44.91 40.83 71.68 49.90 54.21 42.87 60.79 0.20 0.17 0.25 0.50 0.85 Matched[2723]
YHR179W OYE2 "Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye3p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism" Verified chr8:462502-463704 462502-463704 98.6% 1492.94 1850.57 1497.15 1347.86 1697.05 1600.90 1671.75 1422.51 1648.98 6.17 5.77 6.83 0.21 0.46 Matched[2724]
YHR180W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr8:465178-465669 465178-465669 97.0% 58.68 64.97 48.21 37.73 123.66 64.97 61.83 42.97 94.31 0.23 0.17 0.39 1.13 0.15 Covered[2725]
YHR180W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps dubious ORF YHR180C-B and long terminal repeat YHRCsigma3" Dubious chr8:466932-467114 466932-467114 74.0% 7.38 0.00 0.00 7.38 0.00 0.00 3.69 3.69 0.00 0.01 0.01 0.00 -Inf NaN
YHR180C-B "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the dubious ORF YHR180W-A" Dubious chr8:466958-467062 466958-467062 68.5% 0.00 0.00 0.00 13.90 0.00 0.00 0.00 6.95 0.00 0.00 0.03 0.00 -Inf NaN
YHR181W SVP26 "Integral membrane protein of the early Golgi apparatus and endoplasmic reticulum, involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment" Verified chr8:467228-467914 467228-467914 99.2% 397.60 407.87 349.19 328.65 338.92 239.15 402.74 338.92 289.03 1.49 1.38 1.20 -0.23 -0.19 Matched[2726]
YHR182W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and cytoplasm Uncharacterized chr8:468219-470576 468219-470576 98.8% 61.80 48.50 48.93 37.77 38.20 30.47 55.15 43.35 34.34 0.20 0.18 0.14 -0.34 0.34 Matched[2727]
YHR183W GND1 "6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone and adaptation to oxidative stress" Verified chr8:470960-472429 470960-472429 98.4% 2724.11 2740.70 2576.19 2238.18 1412.17 1283.60 2732.41 2407.19 1347.89 10.09 9.77 5.58 -0.84 -0.81 Matched[2728]
YHR182C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr8:470939-471412 470939-471412 98.8% 1587.32 1783.87 1651.42 1595.87 764.82 905.82 1685.60 1623.64 835.32 6.22 6.59 3.46 -0.96 NaN Covered/w/another[2728]
YHR184W SSP1 Protein involved in the control of meiotic nuclear division and coordination of meiosis with spore formation; transcription is induced midway through meiosis Verified chr8:472744-474459 472744-474459 98.8% 13.57 6.49 16.52 14.16 10.62 11.80 10.03 15.34 11.21 0.04 0.06 0.05 -0.45 -0.49 Frag<80[2729]
YHR185C PFS1 "Sporulation protein required for prospore membrane formation at selected spindle poles, ensures functionality of all four spindle pole bodies during meiosis II; not required for meiotic recombination or meiotic chromosome segregation" Verified chr8:474627-475340 474627-475340 99.3% 4.23 9.88 4.23 8.47 5.64 15.52 7.06 6.35 10.58 0.03 0.03 0.04 0.74 -0.62
YHR186C KOG1 "Subunit of TORC1, a rapamycin-sensitive complex involved in growth control that contains Tor1p or Tor2p, Lst8p and Tco89p; contains four HEAT repeats and seven WD-40 repeats; may act as a scaffold protein to couple TOR and its effectors" Verified chr8:475999-480672 475999-480672 99.0% 99.58 82.73 80.79 69.55 35.64 48.39 91.16 75.17 42.01 0.34 0.31 0.17 -0.84 -0.11 Matched[2730]
YHR187W IKI1 "Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; iki1 mutations confer resistance to the K. lactis toxin zymocin" Verified chr8:480990-481919 480990-481919 98.7% 139.38 80.58 116.52 105.63 35.93 37.02 109.98 111.07 36.48 0.41 0.45 0.15 -1.61 -0.66 Matched[2731]
YHR188C GPI16 Transmembrane protein subunit of the glycosylphosphatidylinositol transamidase complex that adds GPIs to newly synthesized proteins; human PIG-Tp homolog Verified chr8:482005-483837 482005-483837 98.6% 344.53 388.77 394.86 376.05 311.90 332.92 366.65 385.46 322.41 1.35 1.56 1.34 -0.26 0.22 Matched[2732]
YHR189W PTH1 One of two (see also PTH2) mitochondrially-localized peptidyl-tRNA hydrolases; dispensable for cell growth and for mitochondrial respiration Verified chr8:484028-484600 484028-484600 98.2% 78.23 78.23 64.00 58.67 90.67 72.89 78.23 61.34 81.78 0.29 0.25 0.34 0.42 1.16 Matched[2733]
YHR190W ERG9 "Farnesyl-diphosphate farnesyl transferase (squalene synthase), joins two farnesyl pyrophosphate moieties to form squalene in the sterol biosynthesis pathway" Verified chr8:484845-486179 484845-486179 98.9% 631.80 720.43 604.53 616.65 849.97 613.62 676.12 610.59 731.80 2.50 2.48 3.03 0.26 0.38 Matched[2734]
YHR191C CTF8 Subunit of a complex with Ctf18p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion Verified chr8:486230-486631 486230-486631 99.4% 112.58 125.09 112.58 140.10 245.18 135.10 118.84 126.34 190.14 0.44 0.51 0.79 0.59 0.08 Matched[2735]
YHR192W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS Uncharacterized chr8:486826-487662 486826-487662 98.7% 199.77 194.93 176.76 171.92 233.67 144.08 197.35 174.34 188.87 0.73 0.71 0.78 0.12 -0.11 Matched[2736]
YHR193C EGD2 "Alpha subunit of the heteromeric nascent polypeptide-associated complex (NAC) involved in protein sorting and translocation, associated with cytoplasmic ribosomes" Verified chr8:487712-488236 487712-488236 98.9% 4115.61 3739.88 4050.10 3466.28 2591.52 1967.24 3927.75 3758.19 2279.38 14.50 15.26 9.44 -0.72 -1.32 Matched[2737]
YHR194W MDM31 "Mitochondrial inner membrane protein with similarity to Mdm32p, required for normal mitochondrial morphology and inheritance; interacts genetically with MMM1, MDM10, MDM12, and MDM34" Verified chr8:488657-490396 488657-490396 98.6% 86.25 118.30 100.82 100.24 129.37 108.98 102.28 100.53 119.18 0.38 0.41 0.49 0.25 0.80 Matched[2738]
YHR193C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps verified ORF MDM31" Dubious chr8:488653-489027 488653-489027 98.9% 62.01 75.49 80.88 80.88 78.18 56.62 68.75 80.88 67.40 0.25 0.33 0.28 -0.26 NaN Covered/w/another[2738]
YHR195W NVJ1 Nuclear envelope protein that interacts with the vacuolar membrane protein Vac8p to promote formation of nucleus-vacuole junctions during piecemeal microautophagy of the nucleus (PMN) Verified chr8:490747-491712 490747-491712 98.4% 164.16 208.36 169.42 188.36 421.98 337.79 186.26 178.89 379.88 0.69 0.73 1.57 1.09 1.20 Frag>80[2739,2740]
YHR196W UTP9 "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" Verified chr8:491931-493658 491931-493658 98.7% 293.05 215.10 167.04 132.46 22.86 7.03 254.07 149.75 14.95 0.94 0.61 0.06 -3.32 -3.95 Matched[2741]
YHR197W RIX1 "Essential component of the Rix1 complex (Rix1p, Ipi1p, Ipi3p) that is required for processing of ITS2 sequences from 35S pre-rRNA; Rix1 complex associates with Mdn1p in pre-60S ribosomal particles" Verified chr8:493896-496187 493896-496187 98.9% 144.19 60.85 69.23 56.00 10.14 2.20 102.52 62.61 6.17 0.38 0.25 0.03 -3.34 -2.53 Matched[2742]
YHR198C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr8:496315-497280 496315-497280 99.0% 100.42 141.21 155.86 162.13 353.56 214.44 120.82 159.00 284.00 0.45 0.65 1.18 0.84 0.83 Frag>80[2743,2744,2745]
YHR199C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr8:497490-498422 497490-498422 98.7% 221.42 301.74 261.58 211.65 531.84 412.45 261.58 236.61 472.14 0.97 0.96 1.96 1.00 1.11 Frag>80[2745,2746]
YHR199C-A Putative protein of unknown function; transcribed sequence appears to contain an intron Uncharacterized chr8:498571-498859 498571-498719,498787-498859 98.6% 54.82 95.93 73.09 63.95 173.58 41.11 75.37 68.52 107.35 0.28 0.28 0.44 0.65 NaN Covered[2746]
YHR200W RPN10 Non-ATPase base subunit of the 19S regulatory particle (RP) of the 26S proteasome; N-terminus plays a role in maintaining the structural integrity of the RP; binds selectively to polyubiquitin chains; homolog of the mammalian S5a protein Verified chr8:499079-499885 499079-499885 98.4% 531.65 530.39 564.41 507.72 821.42 532.91 531.02 536.06 677.17 1.96 2.18 2.81 0.34 0.39 Covered/w/another[2747]
YHR201C PPX1 "Exopolyphosphatase, hydrolyzes inorganic polyphosphate (poly P) into Pi residues; located in the cytosol, plasma membrane, and mitochondrial matrix" Verified chr8:499950-501143 499950-501143 99.3% 363.47 321.30 317.09 260.59 258.90 185.53 342.39 288.84 222.21 1.26 1.17 0.92 -0.38 -0.31 Covered/w/another[2747]
YHR202W "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole, while HA-tagged protein is found in the soluble fraction, suggesting cytoplasmic localization" Uncharacterized chr8:502388-504196 502388-504196 98.9% 55.92 102.33 75.49 81.64 104.57 92.83 79.13 78.57 98.70 0.29 0.32 0.41 0.33 0.61 Matched[2748]
YHR203C RPS4B Protein component of the small (40S) ribosomal subunit; identical to Rps4Ap and has similarity to rat S4 ribosomal protein Verified chr8:504476-505530 504476-505247,505517-505530 24.6% 5280.41 4389.99 4861.09 4400.35 1232.10 1206.21 4835.20 4630.72 1219.15 17.85 18.80 5.05 -1.93 -1.92 Frag>80[2749,2750]
YHR204W MNL1 Alpha mannosidase-like protein of the endoplasmic reticulum required for degradation of glycoproteins but not for processing of N-linked oligosaccharides Verified chr8:506319-508709 506319-508709 98.9% 134.01 138.66 112.03 90.89 49.46 32.55 136.34 101.46 41.01 0.50 0.41 0.17 -1.31 -0.99 Covered/w/another[2751]
YHR205W SCH9 "Protein kinase involved in transcriptional activation of osmostress-responsive genes; regulates G1 progression, cAPK activity, nitrogen activation of the FGM pathway; involved in life span regulation; homologous to mammalian Akt/PKB" Verified chr8:509363-511837 509363-511837 98.8% 215.55 204.50 204.50 177.10 121.88 157.06 210.02 190.80 139.47 0.78 0.77 0.58 -0.45 0.37 Covered/w/another[2751]
YHR206W SKN7 "Nuclear response regulator and transcription factor, part of a branched two-component signaling system; required for optimal induction of heat-shock genes in response to oxidative stress; involved in osmoregulation" Verified chr8:512732-514600 512732-514600 99.0% 161.13 123.28 138.96 112.47 77.32 75.16 142.20 125.71 76.24 0.52 0.51 0.32 -0.72 -0.05 Matched[2752]
YHR207C SET5 "Zinc-finger protein of unknown function, contains one canonical and two unusual fingers in unusual arrangements; deletion enhances replication of positive-strand RNA virus" Verified chr8:514905-516485 514905-516485 99.3% 138.19 164.93 122.27 140.10 192.32 149.65 151.56 131.18 170.98 0.56 0.53 0.71 0.38 0.25 Covered[2753]
YHR208W BAT1 "Mitochondrial branched-chain amino acid aminotransferase, homolog of murine ECA39; highly expressed during logarithmic phase and repressed during stationary phase" Verified chr8:517532-518713 517532-518713 98.9% 1794.10 2109.80 1505.78 1401.40 329.39 230.14 1951.95 1453.59 279.77 7.21 5.90 1.16 -2.38 -2.37 Matched[2754]
YHR209W Putative S-adenosylmethionine-dependent methyltransferase; mediates cantharidin resistance Uncharacterized chr8:519437-520312 519437-520312 98.8% 91.30 91.30 98.23 77.43 389.46 240.38 91.30 87.83 314.92 0.34 0.36 1.30 1.84 2.04 Matched[2755]
YHR210C Putative protein of unknown function; non-essential gene; highly expressed under anaeorbic conditions; sequence similarity to aldose 1-epimerases such as GAL10 Uncharacterized chr8:520712-521737 520712-521737 98.9% 18.72 29.56 29.56 26.60 24.63 19.71 24.14 28.08 22.17 0.09 0.11 0.09 -0.34 -0.17 Matched[2756]
YHR211W FLO5 "Lectin-like cell wall protein (flocculin) involved in flocculation, binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin resistant but heat labile; similar to Flo1p" Verified chr8:525392-528619 525392-528619 20.9% 59.24 56.28 35.54 37.03 41.47 38.51 57.76 36.29 39.99 0.21 0.15 0.17 0.14 0.49 Overlap[2757]
YHR212C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr8:537759-538094 537759-538094 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.65
YHR212W-A "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr8:538742-538945 538742-538945 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YHR213W Putative protein of unknown function Uncharacterized chr8:539151-539747 539151-539747 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.55
YHR213W-A "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr8:540549-540782 540549-540782 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YHR213W-B "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr8:540800-541099 540800-541099 3.9% 0.00 0.00 0.00 0.00 0.00 85.41 0.00 0.00 42.70 0.00 0.00 0.18 Inf NaN
YHR214W Putative protein of unknown function; predicted to be a glycosylphosphatidylinositol-modified (GPI) protein Uncharacterized chr8:541651-542262 541651-542262 0.7% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.04
YHR214W-A "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; similar to the fungal specific protein encoded by YAR068W; induced by zinc deficiency" Dubious chr8:543008-543493 543008-543493 1.2% 0.00 170.21 0.00 170.21 0.00 0.00 85.11 85.11 0.00 0.31 0.35 0.00 -Inf -0.13
YHR214C-D "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr8:550648-550941 550648-550941 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YHR214C-E "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr8:551200-551499 551200-551499 13.0% 0.00 25.64 0.00 0.00 51.28 25.64 12.82 0.00 38.46 0.05 0.00 0.16 Inf NaN
YHR215W PHO12 "One of three repressible acid phosphatases, a glycoprotein that is transported to the cell surface by the secretory pathway; nearly identical to Pho11p; upregulated by phosphate starvation" Verified chr8:552099-553502 552099-553502 3.1% 614.80 432.64 683.11 387.10 45.54 68.31 523.72 535.10 56.93 1.93 2.17 0.24 -3.23 -1.88 Frag<80[2760]
YHR216W IMD2 "Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, expression is induced by mycophenolic acid resulting in resistance to the drug, expression is repressed by nutrient limitation" Verified chr8:554396-555967 554396-555967 24.7% 1359.12 1709.86 1297.23 1194.07 268.21 172.79 1534.49 1245.65 220.50 5.66 5.06 0.91 -2.50 -1.96 Frag<80[2761,2762,2763,2764,2765]
YHR217C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; located in the telomeric region TEL08R." Dubious chr8:556581-557042 556581-557042 23.7% 0.00 9.14 0.00 0.00 0.00 0.00 4.57 0.00 0.00 0.02 0.00 0.00 NaN -0.23
YHR218W Helicase-like protein encoded within the telomeric Y' element Uncharacterized chr8:558014-559924 558014-558615,558715-559924 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.39
YHR218W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr8:559932-560249 559932-560249 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YHR219W Putative protein of unknown function with similarity to helicases; located in the telomere region on the right arm of chromosome VIII Uncharacterized chr8:560173-562047 560173-562047 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.28
YHR219C-A "Dubious open reading frame unlikely to encode a functional protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr8:561199-561681 561199-561681 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YIL177W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the uncharacterized gene YIL177C" Dubious chr9:846-1328 846-1328 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YIL177C Putative protein of unknown function; similarity to DNA helicases that are encoded within subtelomeric Y' elements and induced in telomerase deficient survivors Uncharacterized chr9:483-6147 483-4598,4987-6147 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.24
YIL176C Hypothetical protein Uncharacterized chr9:8793-9155 8793-9155 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.67
YIL173W VTH1 "Putative membrane glycoprotein with strong similarity to Vth2p and Pep1p/Vps10p, may be involved in vacuolar protein sorting" Verified chr9:11492-16141 11492-16141 0.1% 252.63 0.00 0.00 252.63 0.00 0.00 126.32 126.32 0.00 0.47 0.51 0.00 -Inf 0.23
YIL171W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr9:18260-18712 18260-18712 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YIL172C Putative protein of unknown function with similarity to glucosidases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr9:16784-18553 16784-18553 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.33
YIL169C "Putative protein of unknown function; serine/threonine rich and highly similar to YOL155C, a putative glucan alpha-1,4-glucosidase; transcript is induced in both high and low pH environments; YIL169C is a non-essential gene" Uncharacterized chr9:23119-26106 23119-26106 62.9% 337.36 378.87 263.93 328.32 101.10 222.42 358.11 296.12 161.76 1.32 1.20 0.67 -0.87 0.62 Frag<80[2768,2769]
YIL166C Putative protein with similarity to the allantoate permease (Dal5p) subfamily of the major facilitator superfamily; mRNA expression is elevated by sulfur limitation; YIL166C is a non-essential gene Uncharacterized chr9:30938-32566 30938-32566 99.0% 31.63 38.45 28.53 24.19 65.74 50.24 35.04 26.36 57.99 0.13 0.11 0.24 1.14 0.77 Covered[2771]
YIL165C "Putative protein of unknown function; in closely related species and other S. cerevisiae strain backgrounds YIL165C and adjacent ORF, YIL164C, likely constitute a single ORF encoding a nitrilase gene" Uncharacterized chr9:33718-34077 33718-34077 99.1% 81.28 137.34 89.69 95.29 126.12 95.29 109.31 92.49 110.71 0.40 0.38 0.46 0.26 0.30 Covered/w/another[2772]
YIL164C NIT1 "Nitrilase, member of the nitrilase branch of the nitrilase superfamily; in closely related species and other S. cerevisiae strain backgrounds YIL164C and adjacent ORF, YIL165C, likely constitute a single ORF encoding a nitrilase gene" Verified chr9:34087-34686 34087-34686 98.8% 70.87 96.18 84.36 55.68 101.24 43.87 83.52 70.02 72.55 0.31 0.28 0.30 0.05 0.32 Covered/w/another[2772]
YIL163C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr9:36899-37252 36899-37252 98.8% 65.75 34.30 22.87 14.29 31.44 17.15 50.02 18.58 24.30 0.18 0.08 0.10 0.39 -0.08 Covered/w/another[2772]
YIL162W SUC2 "Invertase, sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively" Verified chr9:37385-38983 37385-38983 99.0% 184.51 133.96 319.10 462.53 150.39 140.28 159.23 390.82 145.33 0.59 1.59 0.60 -1.43 -1.00 Matched[2773]
YIL161W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; mRNA is enriched in Scp160p-associated mRNPs; YIL161W is a non-essential gene Uncharacterized chr9:39433-40140 39433-40140 98.3% 192.47 192.47 132.14 143.64 209.71 142.20 192.47 137.89 175.95 0.71 0.56 0.73 0.35 0.24 Matched[2774]
YIL160C POT1 "3-ketoacyl-CoA thiolase with broad chain length specificity, cleaves 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA during beta-oxidation of fatty acids" Verified chr9:40191-41444 40191-41444 99.0% 26.58 28.19 25.78 16.92 76.52 45.11 27.39 21.35 60.81 0.10 0.09 0.25 1.51 1.89 Matched[2775]
YIL159W BNR1 "Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables, functionally redundant with BNI1" Verified chr9:41825-45952 41825-45952 98.9% 48.25 33.80 34.29 29.63 16.65 13.96 41.02 31.96 15.31 0.15 0.13 0.06 -1.06 -0.55 Frag<80[2776,2777]
YIL158W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole Uncharacterized chr9:46201-46815 46201-46815 98.4% 348.66 277.61 269.35 232.99 107.41 36.35 313.14 251.17 71.88 1.16 1.02 0.30 -1.80 -1.07 Matched[2778]
YIL156W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr9:47292-47693 47292-47693 98.7% 199.16 204.20 214.29 234.45 496.64 302.52 201.68 224.37 399.58 0.74 0.91 1.66 0.83 NaN Matched[2779]
YIL157C COA1 Protein required for assembly of the cytochrome c oxidase complex (complex IV of the mitochondrial respiratory chain); probable mitochondrial inner membrane protein; interacts with COX1 regulatory proteins MSS1 and COX14 Uncharacterized chr9:46949-47542 46949-47542 98.9% 362.40 389.62 360.70 394.73 797.96 464.48 376.01 377.71 631.22 1.39 1.53 2.62 0.74 1.18 Matched[2779]
YIL156W-B "Putative protein of unknown function, originally identified based on homology to Ashbya gossypii and other related yeasts" Uncharacterized chr9:47690-47973 47690-47698,47761-47973 98.7% 333.08 323.95 351.33 360.46 825.86 451.71 328.52 355.89 638.78 1.21 1.44 2.65 0.84 NaN Matched[2780]
YIL156W UBP7 Ubiquitin-specific protease that cleaves ubiquitin-protein fusions Verified chr9:48091-51306 48091-51306 98.8% 71.78 85.63 76.50 68.63 74.61 94.44 78.70 72.56 84.53 0.29 0.29 0.35 0.22 0.67 Matched[2781]
YIL155C GUT2 "Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by both glucose and cAMP and derepressed by non-fermentable carbon sources in a Snf1p, Rsf1p, Hap2/3/4/5 complex dependent manner" Verified chr9:51759-53708 51759-53708 98.6% 127.42 171.11 305.81 317.25 899.23 935.64 149.27 311.53 917.44 0.55 1.26 3.80 1.56 1.92 Frag>80[2782,2783]
YIL154C IMP2' "Transcriptional activator involved in maintenance of ion homeostasis and protection against DNA damage caused by bleomycin and other oxidants, contains a C-terminal leucine-rich repeat" Verified chr9:53981-55021 53981-55021 98.4% 261.54 307.40 264.47 236.16 418.66 359.13 284.47 250.32 388.89 1.05 1.02 1.61 0.64 0.81 Covered/w/another[2784]
YIL153W RRD1 "Activator of the phosphotyrosyl phosphatase activity of PP2A, peptidyl-prolyl cis/trans-isomerase; regulates G1 phase progression, microtubule dynamics, bud morphogenesis and DNA repair; subunit of the Tap42p-Sit4p-Rrd1p complex" Verified chr9:55198-56379 55198-56379 98.5% 128.02 129.74 166.68 140.91 250.03 195.04 128.88 153.80 222.53 0.48 0.62 0.92 0.53 0.73 Covered/w/another[2784]
YIL152W Putative protein of unknown function Uncharacterized chr9:56545-57252 56545-57252 98.7% 155.93 210.29 140.19 111.58 246.05 183.11 183.11 125.89 214.58 0.68 0.51 0.89 0.77 0.69 Covered/w/another[2784]
YIL151C "Putative protein of unknown function, predicted to contain a PINc (PilT N terminus) domain" Uncharacterized chr9:57338-60694 57338-60694 99.2% 131.52 134.52 101.49 82.27 72.96 72.96 133.02 91.88 72.96 0.49 0.37 0.30 -0.33 0.07
YIL150C MCM10 Essential chromatin-associated protein involved in the initiation of DNA replication; required for the association of the MCM2-7 complex with replication origins Verified chr9:61013-62728 61013-62728 99.2% 34.67 21.74 19.39 17.63 10.58 14.69 28.21 18.51 12.63 0.10 0.08 0.05 -0.55 0.28 Frag<80[2786]
YIL149C MLP2 "Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the nuclear interior; involved in the Tel1p pathway that controls telomere length" Verified chr9:63028-68067 63028-68067 99.5% 197.09 182.72 166.57 153.00 88.97 125.27 189.90 159.78 107.12 0.70 0.65 0.44 -0.58 0.08 Matched[2787]
YIL148W RPL40A "Fusion protein, identical to Rpl40Bp, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes" Verified chr9:68708-69528 68708-68715,69150-69528 51.7% 11327.36 9927.07 9762.03 7971.66 3705.77 2840.59 10627.21 8866.85 3273.18 39.23 35.99 13.56 -1.44 -0.30 Matched[2788]
YIL147C SLN1 "Histidine kinase osmosensor that regulates a MAP kinase cascade; transmembrane protein with an intracellular kinase domain that signals to Ypd1p and Ssk1p, thereby forming a phosphorelay system similar to bacterial two-component regulators" Verified chr9:69791-73453 69791-73453 99.1% 159.53 139.14 128.12 127.29 54.00 68.88 149.33 127.71 61.44 0.55 0.52 0.25 -1.06 -0.85 Matched[2789]
YIL146C ECM37 Non-essential protein of unknown function Verified chr9:74184-75773 74184-75773 98.8% 66.83 59.82 45.82 35.64 63.64 56.64 63.33 40.73 60.14 0.23 0.17 0.25 0.56 1.24 Matched[2790]
YIL145C PAN6 "Pantothenate synthase, also known as pantoate-beta-alanine ligase, required for pantothenic acid biosynthesis, deletion causes pantothenic acid auxotrophy, homologous to E. coli panC" Verified chr9:76354-77283 76354-77283 99.0% 342.08 331.22 286.70 257.38 217.19 133.57 336.65 272.04 175.38 1.24 1.10 0.73 -0.63 -0.74 Frag>80[2791,2792,2793]
YIL144W TID3 "Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); conserved coiled-coil protein involved in chromosome segregation, spindle checkpoint activity, kinetochore assembly and clustering" Verified chr9:78074-80149 78074-80149 98.8% 138.43 134.04 115.52 101.87 179.37 146.23 136.23 108.69 162.80 0.50 0.44 0.67 0.58 0.83 Covered/w/another[2794]
YIL143C SSL2 "Component of the holoenzyme form of RNA polymerase transcription factor TFIIH, has DNA-dependent ATPase/helicase activity and is required, with Rad3p, for unwinding promoter DNA; involved in DNA repair; homolog of human ERCC3" Verified chr9:80510-83041 80510-83041 99.1% 119.58 118.38 106.82 90.48 171.79 106.03 118.98 98.65 138.91 0.44 0.40 0.58 0.49 0.52 Covered/w/another[2794]
YIL142W CCT2 "Subunit beta of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo" Verified chr9:83302-84885 83302-84885 98.5% 495.35 350.53 433.19 412.05 277.48 231.98 422.94 422.62 254.73 1.56 1.72 1.06 -0.73 -0.21 Matched[2795]
YIL142C-A "Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr9:83208-83540 83208-83540 97.9% 254.47 193.15 266.73 248.34 119.57 159.43 223.81 257.54 139.50 0.83 1.05 0.58 -0.88 NaN Covered/w/another[2795]
YIL141W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr9:85053-85442 85053-85442 99.3% 31.00 28.41 33.58 10.33 2.58 10.33 29.71 21.96 6.46 0.11 0.09 0.03 -1.77 0.19 Overlap[2796]
YIL140W AXL2 "Integral plasma membrane protein required for axial budding in haploid cells, localizes to the incipient bud site and bud neck; glycosylated by Pmt4p; potential Cdc28p substrate" Verified chr9:85366-87837 85366-87837 99.0% 129.92 113.17 156.88 106.63 41.26 31.46 121.54 131.76 36.36 0.45 0.53 0.15 -1.86 -0.96 Frag>80[2796]
YIL139C REV7 "Processivity subunit of DNA polymerase zeta, which is involved in DNA repair and translesion synthesis; required for mutagenesis induced by DNA damage" Verified chr9:87979-88716 87979-88716 99.3% 118.70 125.52 92.77 75.04 139.16 61.40 122.11 83.91 100.28 0.45 0.34 0.42 0.26 -0.18 Matched[2797]
YIL138C TPM2 "Minor isoform of tropomyosin, binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; appears to have distinct and also overlapping functions with Tpm1p" Verified chr9:89230-89715 89230-89715 99.7% 660.13 796.29 635.38 610.62 1248.07 752.97 728.21 623.00 1000.52 2.69 2.53 4.15 0.68 0.02 Matched[2798]
YIL137C TMA108 Protein that associates with ribosomes; putative metalloprotease Verified chr9:89948-92788 89948-92788 98.9% 173.63 171.49 173.63 162.95 156.55 163.31 172.56 168.29 159.93 0.64 0.68 0.66 -0.07 0.47 Covered[2799]
YIL136W OM45 "Protein of unknown function, major constituent of the mitochondrial outer membrane; located on the outer (cytosolic) face of the outer membrane" Verified chr9:93619-94800 93619-94800 97.6% 107.50 274.81 273.94 273.07 3119.09 2574.68 191.15 273.51 2846.88 0.71 1.11 11.80 3.38 2.94 Matched[2800]
YIL135C VHS2 "Cytoplasmic protein of unknown function; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; similar to Mlf3p" Verified chr9:95065-96375 95065-96375 98.7% 184.01 228.08 221.89 204.11 280.65 241.22 206.04 213.00 260.94 0.76 0.86 1.08 0.29 0.79 Matched[2801]
YIL134C-A "Putative protein of unknown function, identified by fungal homology and RT-PCR" Uncharacterized chr9:96522-96725 96522-96725 99.1% 0.00 9.89 4.95 9.89 14.84 4.95 4.95 7.42 9.89 0.02 0.03 0.04 0.42 NaN Covered/w/another[2802]
YIL134W FLX1 "Protein required for transport of flavin adenine dinucleotide (FAD), a synthesis product of riboflavin, across the mitochondrial membrane" Verified chr9:97395-98330 97395-98330 98.7% 107.18 108.26 90.94 89.86 93.10 46.55 107.72 90.40 69.83 0.40 0.37 0.29 -0.37 -0.32 Covered[2802]
YIL133C RPL16A "N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5.8 S rRNA; has similarity to Rpl16Bp, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p" Verified chr9:98527-99416 98527-99095,99386-99416 90.0% 5076.32 3861.41 4376.26 3453.97 705.61 205.57 4468.86 3915.12 455.59 16.50 15.89 1.89 -3.10 -3.47 Matched[2803]
YIL132C CSM2 Protein required for accurate chromosome segregation during meiosis Verified chr9:99860-100501 99860-100501 99.0% 64.49 95.95 45.62 50.33 58.20 42.47 80.22 47.97 50.33 0.30 0.19 0.21 0.07 0.43 Covered/w/another[2804]
YIL131C FKH1 Forkhead family transcription factor with a minor role in the expression of G2/M phase genes; negatively regulates transcriptional elongation; positive role in chromatin silencing at HML and HMR; regulates donor preference during switching Verified chr9:100781-102235 100781-102235 99.0% 143.67 117.99 102.03 90.92 71.49 63.16 130.83 96.47 67.32 0.48 0.39 0.28 -0.52 -0.14 Covered/w/another[2804]
YIL130W ASG1 "Proposed transcriptional activator, member of the Gal4p family of zinc cluster proteins" Verified chr9:102782-105676 102782-105676 97.5% 156.90 177.44 145.56 134.58 75.08 108.38 167.17 140.07 91.73 0.62 0.57 0.38 -0.61 0.15 Matched[2805]
YIL129C TAO3 "Protein involved in cell morphogenesis and proliferation, associated with protein kinase Cbk1p; mutants activate OCH1 transcription" Verified chr9:106107-113237 106107-113237 99.1% 74.12 91.52 64.50 55.59 63.09 96.33 82.82 60.05 79.71 0.31 0.24 0.33 0.41 0.51 Frag>80[2806,2807,2808]
YIL128W MET18 "DNA repair and TFIIH regulator, required for both nucleotide excision repair (NER) and RNA polymerase II (RNAP II) transcription; involved in telomere maintenance" Verified chr9:113806-116904 113806-116904 99.1% 104.56 98.70 95.44 78.83 62.54 72.97 101.63 87.14 67.75 0.38 0.35 0.28 -0.36 0.14 Matched[2809]
YIL127C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus Uncharacterized chr9:117024-117644 117024-117644 99.3% 210.73 179.93 136.16 110.23 19.45 17.83 195.33 123.19 18.64 0.72 0.50 0.08 -2.72 -3.37 Matched[2810]
YIL126W STH1 ATPase component of the RSC chromatin remodeling complex; required for expression of early meiotic genes; essential helicase-related protein homologous to Snf2p Verified chr9:117992-122071 117992-122071 98.5% 267.03 245.38 218.01 219.00 115.47 147.58 256.21 218.51 131.53 0.95 0.89 0.54 -0.73 -0.10 Matched[2811]
YIL125W KGD1 "Component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes a key step in the tricarboxylic acid (TCA) cycle, the oxidative decarboxylation of alpha-ketoglutarate to form succinyl-CoA" Verified chr9:122689-125733 122689-125733 98.7% 285.73 334.62 358.57 387.84 338.95 414.45 310.17 373.21 376.70 1.14 1.51 1.56 0.01 0.54 Matched[2812]
YIL124W AYR1 "NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase found in lipid particles, ER, and mitochondrial outer membrane; involved in phosphatidic acid biosynthesis; required for spore germination; capable of metabolizing steroid hormones" Verified chr9:126204-127097 126204-127097 98.8% 719.76 956.29 751.45 872.54 2184.18 1444.05 838.03 812.00 1814.12 3.09 3.30 7.52 1.16 0.95 Matched[2813]
YIL123W SIM1 "Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) that may participate in DNA replication, promoter contains SCB regulation box at -300 bp indicating that expression may be cell cycle-regulated" Verified chr9:127661-129578 127661-127662,128149-129578 98.1% 1715.10 1880.92 1781.28 1724.35 524.49 407.78 1798.01 1752.82 466.14 6.64 7.12 1.93 -1.91 -1.65 Matched[2814]
YIL122W POG1 Putative transcriptional activator that promotes recovery from pheromone induced arrest; inhibits both alpha-factor induced G1 arrest and repression of CLN1 and CLN2 via SCB/MCB promoter elements; potential Cdc28p substrate; SBF regulated Verified chr9:130607-131662 130607-131662 98.6% 58.61 75.90 64.37 53.81 102.81 83.59 67.26 59.09 93.20 0.25 0.24 0.39 0.66 1.14 Matched[2815]
YIL121W QDR2 "Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, barban, cisplatin, and bleomycin; may have a role in potassium uptake" Verified chr9:132241-133869 132241-133869 98.8% 471.17 677.54 466.82 472.42 167.83 136.75 574.36 469.62 152.29 2.12 1.91 0.63 -1.62 -1.47 Matched[2816]
YIL120W QDR1 "Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, ketoconazole, fluconazole, and barban" Verified chr9:134414-136105 134414-136105 98.8% 56.24 55.04 40.68 38.29 68.80 41.28 55.64 39.49 55.04 0.21 0.16 0.23 0.48 0.05 Matched[2817]
YIL119C RPI1 Putative transcriptional regulator; overexpression suppresses the heat shock sensitivity of wild-type RAS2 overexpression and also suppresses the cell lysis defect of an mpk1 mutation Verified chr9:136651-137874 136651-137874 99.2% 336.95 501.72 339.42 327.06 316.35 232.32 419.33 333.24 274.34 1.55 1.35 1.14 -0.28 -0.28 Matched[2818]
YIL118W RHO3 Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p Verified chr9:139749-140444 139749-140444 98.7% 500.76 443.99 477.47 468.73 457.09 273.67 472.37 473.10 365.38 1.74 1.92 1.51 -0.37 -0.45 Matched[2819]
YIL117C PRM5 "Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling" Verified chr9:140610-141566 140610-141566 98.7% 139.68 146.03 182.01 149.21 487.83 370.37 142.86 165.61 429.10 0.53 0.67 1.78 1.37 1.08 Matched[2820]
YIL116W HIS5 "Histidinol-phosphate aminotransferase, catalyzes the seventh step in histidine biosynthesis; responsive to general control of amino acid biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts" Verified chr9:142925-144082 142925-144082 98.8% 458.01 657.29 434.41 396.82 299.80 250.86 557.65 415.62 275.33 2.06 1.69 1.14 -0.59 -0.08 Matched[2821]
YIL115W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene NUP159/YIL115C" Dubious chr9:144265-144636 144265-144636 99.5% 345.98 270.30 256.79 202.73 240.57 148.67 308.14 229.76 194.62 1.14 0.93 0.81 -0.24 NaN Covered/w/another[2822]
YIL115C NUP159 "Nucleoporin, subunit of the nuclear pore complex that is found exclusively on the cytoplasmic side, forms a subcomplex with Nup82p and Nsp1p, required for mRNA export" Verified chr9:144324-148706 144324-148706 96.5% 162.86 150.34 136.63 130.24 88.64 82.97 156.60 133.44 85.81 0.58 0.54 0.36 -0.64 -0.34 Matched[2822]
YIL114C POR2 "Putative mitochondrial porin (voltage-dependent anion channel), related to Por1p but not required for mitochondrial membrane permeability or mitochondrial osmotic stability" Verified chr9:149140-149985 149140-149985 99.0% 192.17 192.17 125.33 126.52 204.11 149.20 192.17 125.93 176.65 0.71 0.51 0.73 0.49 0.19 Frag>80[2823,2824]
YIL113W SDP1 "Stress-inducible dual-specificity MAP kinase phosphatase, negatively regulates Slt2p MAP kinase by direct dephosphorylation, diffuse localization under normal conditions shifts to punctate localization after heat shock" Verified chr9:150556-151185 150556-151185 98.4% 30.66 56.49 46.80 56.49 550.33 334.07 43.57 51.64 442.20 0.16 0.21 1.83 3.10 2.87 Frag>80[2825,2826]
YIL112W HOS4 "Subunit of the Set3 complex, which is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate" Verified chr9:151592-154843 151592-154843 98.4% 200.38 229.14 160.68 167.56 253.21 209.45 214.76 164.12 231.33 0.79 0.67 0.96 0.50 0.34 Frag>80[2826,2827,2828]
YIL111W COX5B "Subunit Vb of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; predominantly expressed during anaerobic growth while its isoform Va (Cox5Ap) is expressed during aerobic growth" Verified chr9:155219-155762 155219-155219,155308-155762 98.4% 784.55 2112.93 1014.12 1014.12 3011.14 1943.54 1448.74 1014.12 2477.34 5.35 4.12 10.26 1.29 0.26 Matched[2829]
YIL110W "Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; deletion mutant exhibits a weak vacuolar protein sorting defect, enhanced resistance to caspofungin, and is synthetically lethal with MEN mutants" Uncharacterized chr9:156042-157175 156042-157175 98.8% 165.08 151.70 126.71 120.46 74.06 49.08 158.39 123.59 61.57 0.58 0.50 0.26 -1.01 -0.95 Frag>80[2830,2831,2832]
YIL109C SEC24 "Component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat; involved in ER to Golgi transport, cargo selection and autophagy; required for the binding of the Sec13 complex to ER membranes; homologous to Lst1p and Lss1p" Verified chr9:157382-160162 157382-160162 98.3% 458.68 424.30 496.36 448.08 394.67 479.90 441.49 472.22 437.28 1.63 1.92 1.81 -0.11 0.56 Frag>80[2832,2833]
YIL108W Putative metalloprotease Uncharacterized chr9:160884-162974 160884-162974 98.6% 135.37 137.31 141.68 135.37 188.25 242.11 136.34 138.52 215.18 0.50 0.56 0.89 0.64 1.28 Matched[2834]
YIL107C PFK26 "6-phosphofructo-2-kinase, inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate, has negligible fructose-2,6-bisphosphatase activity, transcriptional regulation involves protein kinase A" Verified chr9:163275-165758 163275-165758 99.2% 172.50 245.56 174.53 156.67 437.96 340.54 209.03 165.60 389.25 0.77 0.67 1.61 1.23 1.62 Matched[2835]
YIL106W MOB1 Component of the mitotic exit network; associates with and is required for the activation and Cdc15p-dependent phosphorylation of the Dbf2p kinase; required for cytokinesis and cell separation; component of the CCR4 transcriptional complex Verified chr9:166412-167441 166412-166431,166517-167441 98.8% 197.07 177.79 183.15 171.37 169.23 107.10 187.43 177.26 138.16 0.69 0.72 0.57 -0.36 0.11 Matched[2836]
YIL105W-A "Dubious open reading frame; completely overlaps the verified gene SLM1; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr9:167661-167801 167661-167801 99.5% 185.38 192.51 206.77 178.25 577.54 527.63 188.95 192.51 552.58 0.70 0.78 2.29 1.52 NaN Covered/w/another[2837]
YIL105C SLM1 "Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; subunit of and phosphorylated by the TORC2 complex" Verified chr9:167578-169638 167578-169638 97.8% 131.52 156.83 159.31 156.33 397.03 342.44 144.17 157.82 369.73 0.53 0.64 1.53 1.23 1.51 Matched[2837]
YIL104C SHQ1 "Essential nuclear protein, required for accumulation of box H/ACA snoRNAs and for rRNA processing; interacts with Naf1p" Verified chr9:169979-171502 169979-171502 99.3% 74.03 56.84 48.91 36.35 19.17 10.58 65.43 42.63 14.87 0.24 0.17 0.06 -1.52 -1.56 Matched[2838]
YIL103W DPH1 "Protein required, along with Dph2p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph2p and Kti11p" Verified chr9:171748-173025 171748-173025 98.8% 171.13 149.74 135.48 97.45 62.59 29.31 160.43 116.46 45.95 0.59 0.47 0.19 -1.34 -3.40 Frag>80[2839,2840]
YIL102C-A "Putative protein of unknown function, identified based on comparisons of the genome sequences of six Saccharomyces species" Uncharacterized chr9:173362-173589 173362-173589 98.5% 133.61 142.51 115.79 138.06 129.15 71.26 138.06 126.93 100.20 0.51 0.52 0.42 -0.34 NaN Covered[2840]
YIL102C Putative protein of unknown function Uncharacterized chr9:174579-174884 174579-174884 99.2% 3.29 9.88 0.00 0.00 16.47 19.77 6.59 0.00 18.12 0.02 0.00 0.08 Inf 0.18 Matched[2841]
YIL101C XBP1 "Transcriptional repressor that binds to promoter sequences of the cyclin genes, CYS3, and SMF2; expression is induced by stress or starvation during mitosis, and late in meiosis; member of the Swi4p/Mbp1p family; potential Cdc28p substrate" Verified chr9:175304-177247 175304-177247 98.3% 48.13 48.13 96.25 69.05 347.86 366.70 48.13 82.65 357.28 0.18 0.34 1.48 2.11 2.29 Frag>80[2842,2843]
YIL100W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the dubious ORF YIL100C-A" Dubious chr9:177370-177723 177370-177723 95.0% 5.95 17.85 11.90 5.95 50.56 41.64 11.90 8.92 46.10 0.04 0.04 0.19 2.37 2.41 Covered/w/another[2844]
YIL100C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr9:177340-177678 177340-177678 95.2% 6.20 12.40 12.40 12.40 55.78 34.09 9.30 12.40 44.93 0.03 0.05 0.19 1.86 NaN Covered/w/another[2844]
YIL099W SGA1 "Intracellular sporulation-specific glucoamylase involved in glycogen degradation; induced during starvation of a/a diploids late in sporulation, but dispensable for sporulation" Verified chr9:178001-179650 178001-179650 98.5% 12.30 22.76 23.37 23.99 193.11 142.68 17.53 23.68 167.90 0.06 0.10 0.70 2.83 2.75 Matched[2844]
YIL098C FMC1 "Mitochondrial matrix protein, required for assembly or stability at high temperature of the F1 sector of mitochondrial F1F0 ATP synthase; null mutant temperature sensitive growth on glycerol is suppressed by multicopy expression of Odc1p" Verified chr9:179769-180236 179769-180236 99.5% 191.12 182.53 184.68 186.83 414.46 272.73 186.83 185.76 343.59 0.69 0.75 1.42 0.89 0.45 Matched[2845]
YIL097W FYV10 "Protein of unknown function, required for survival upon exposure to K1 killer toxin; involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains CTLH domain" Verified chr9:180424-181974 180424-181974 99.0% 56.00 66.41 56.00 68.37 226.59 175.80 61.20 62.18 201.19 0.23 0.25 0.83 1.69 1.68 Matched[2846]
YIL096C Putative protein of unknown function; associates with precursors of the 60S ribosomal subunit Uncharacterized chr9:182114-183124 182114-183124 99.4% 117.39 61.68 55.71 37.80 5.97 8.95 89.54 46.76 7.46 0.33 0.19 0.03 -2.65 -2.75 Matched[2847]
YIL095W PRK1 Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton through the phosphorylation of the Pan1p-Sla1p-End3p protein complex Verified chr9:183934-186366 183934-186366 98.9% 81.01 76.03 71.04 61.90 92.23 79.76 78.52 66.47 86.00 0.29 0.27 0.36 0.37 0.48 Matched[2848]
YIL094C LYS12 "Homo-isocitrate dehydrogenase, an NAD-linked mitochondrial enzyme required for the fourth step in the biosynthesis of lysine, in which homo-isocitrate is oxidatively decarboxylated to alpha-ketoadipate" Verified chr9:186514-187629 186514-187629 99.0% 1051.19 1102.80 982.38 808.54 334.10 239.03 1077.00 895.46 286.57 3.98 3.63 1.19 -1.64 -1.29 Frag>80[2849,2850]
YIL093C RSM25 Mitochondrial ribosomal protein of the small subunit Verified chr9:187987-188781 187987-188781 99.2% 249.68 242.08 225.60 259.82 171.10 144.49 245.88 242.71 157.79 0.91 0.99 0.65 -0.62 -0.52 Matched[2851]
YIL092W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus Uncharacterized chr9:189063-190964 189063-190964 98.7% 63.38 64.98 37.82 38.35 21.84 16.51 64.18 38.08 19.17 0.24 0.15 0.08 -0.99 -0.82 Covered/w/another[2852]
YIL091C Protein required for cell viability Uncharacterized chr9:191027-193192 191027-193192 99.3% 139.47 101.35 90.19 68.80 8.83 4.18 120.41 79.50 6.51 0.44 0.32 0.03 -3.61 -3.21 Covered/w/another[2852]
YIL090W ICE2 Integral ER membrane protein with type-III transmembrane domains; mutations cause defects in cortical ER morphology in both the mother and daughter cells Verified chr9:193592-195067 193592-195067 98.9% 160.94 162.31 134.91 104.09 74.65 58.21 161.62 119.50 66.43 0.60 0.49 0.28 -0.85 -0.37 Matched[2853]
YIL089W Putative protein of unknown function Uncharacterized chr9:195596-196213 195596-196213 99.2% 45.68 70.15 47.31 45.68 109.31 60.36 57.92 46.50 84.83 0.21 0.19 0.35 0.87 0.62 Matched[2854]
YIL088C AVT7 "Putative transporter, member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters" Verified chr9:197928-199400 197928-199400 98.9% 570.37 589.58 563.50 549.78 400.84 346.61 579.98 556.64 373.72 2.14 2.26 1.55 -0.57 -0.31 Frag>80[2855,2856]
YIL087C "Putative protein of unknown function; GFP-fusion protein is induced in response to the DNA-damaging agent MMS; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr9:199643-200116 199643-200116 98.3% 115.93 178.19 158.87 191.07 809.37 463.73 147.06 174.97 636.55 0.54 0.71 2.64 1.86 1.79 Matched[2857]
YIL086C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr9:200150-200458 200150-200458 99.0% 45.75 26.14 45.75 39.22 205.88 130.72 35.95 42.48 168.30 0.13 0.17 0.70 1.99 0.32 Matched[2857]
YIL085C KTR7 Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family Verified chr9:200487-202040 200487-202040 99.2% 258.29 238.82 242.71 228.44 181.71 173.92 248.55 235.57 177.82 0.92 0.96 0.74 -0.41 0.12 Covered/w/another[2858]
YIL084C SDS3 "Component of the Rpd3p/Sin3p deacetylase complex required for its structural integrity and catalytic activity, involved in transcriptional silencing and required for sporulation; cells defective in SDS3 display pleiotropic phenotypes" Verified chr9:202273-203256 202273-203256 99.2% 100.38 76.82 75.80 78.87 79.90 78.87 88.60 77.34 79.39 0.33 0.31 0.33 0.04 0.76 Covered/w/another[2858]
YIL083C "Putative phosphopantothenoylcysteine synthetase (PPCS) that catalyzes the second step in the biosynthesis of coenzyme A from pantothenate; conserved in bacteria, humans, and plants; essential for viability" Uncharacterized chr9:203553-204650 203553-204650 99.0% 244.79 359.83 192.34 192.34 109.51 59.82 302.31 192.34 84.67 1.12 0.78 0.35 -1.18 -1.34 Matched[2859]
YIL082W Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag Dubious chr9:205632-206504 205632-206504 8.0% 128.27 114.01 57.01 114.01 57.01 71.26 121.14 85.51 64.13 0.45 0.35 0.27 -0.42 -0.75 Frag<80[2860,2861]
YIL079C AIR1 "RING finger protein that interacts with the arginine methyltransferase Hmt1p to regulate methylation of Npl3p, which modulates Npl3p function in mRNA processing and export; has similarity to Air2p" Verified chr9:210920-212002 210920-212002 99.2% 121.91 107.95 80.96 74.45 11.17 0.93 114.93 77.71 6.05 0.42 0.32 0.03 -3.68 -1.47 Matched[2864]
YIL078W THS1 "Threonyl-tRNA synthetase, essential cytoplasmic protein" Verified chr9:212496-214700 212496-214700 98.7% 2047.28 1503.76 1839.62 1796.89 637.25 731.90 1775.52 1818.25 684.57 6.55 7.38 2.84 -1.41 -1.44 Matched[2865]
YIL077C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)" Uncharacterized chr9:214988-215950 214988-215950 99.1% 106.83 140.35 127.78 146.64 240.90 144.54 123.59 137.21 192.72 0.46 0.56 0.80 0.49 0.82 Frag>80[2866,2867,2868]
YIL076W SEC28 "Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein traffic; stabilizes Cop1p, the alpha-COP and the coatomer complex; non-essential for cell growth" Verified chr9:216655-217545 216655-217545 98.9% 830.60 837.41 760.25 824.93 1090.44 773.86 834.00 792.59 932.15 3.08 3.22 3.86 0.23 0.36 Matched[2869]
YIL075C RPN2 "Subunit of the 26S proteasome, substrate of the N-acetyltransferase Nat1p" Verified chr9:217860-220697 217860-220697 99.1% 707.57 627.56 697.61 669.88 946.86 849.43 667.57 683.74 898.15 2.46 2.78 3.72 0.39 0.59 Matched[2871]
YIL074C SER33 "3-phosphoglycerate dehydrogenase, catalyzes the first step in serine and glycine biosynthesis; isozyme of Ser3p" Verified chr9:221078-222487 221078-222487 85.9% 372.48 385.70 379.92 298.98 247.77 133.80 379.09 339.45 190.78 1.40 1.38 0.79 -0.83 -0.54 Matched[2872]
YIL073C SPO22 "Meiosis-specific protein essential for chromosome synapsis, similar to phospholipase A2, involved in completion of nuclear divisions during meiosis; induced early in meiosis" Verified chr9:222934-225951 222934-225806,225897-225951 99.3% 43.66 49.51 34.04 27.50 18.91 12.72 46.59 30.77 15.82 0.17 0.12 0.07 -0.96 1.27 Frag<80[2873]
YIL072W HOP1 Meiosis-specific DNA binding protein that displays Red1p dependent localization to the unsynapsed axial-lateral elements of the synaptonemal complex; required for homologous chromosome synapsis and chiasma formation Verified chr9:226599-228416 226599-228416 98.9% 28.93 30.05 21.14 17.80 46.74 28.38 29.49 19.47 37.56 0.11 0.08 0.16 0.95 0.91 Matched[2874]
YIL071W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr9:228547-229023 228547-229023 99.6% 111.58 143.16 120.00 105.26 197.89 98.95 127.37 112.63 148.42 0.47 0.46 0.61 0.40 NaN Covered/w/another[2875]
YIL071C PCI8 "Possible shared subunit of Cop9 signalosome (CSN) and eIF3, binds eIF3b subunit Prt1p, has possible dual functions in transcriptional and translational control, contains a PCI (Proteasome-COP9 signalosome (CSN)-eIF3) domain" Verified chr9:228657-229991 228657-229991 99.4% 71.61 101.01 84.42 72.36 131.16 91.21 86.31 78.39 111.18 0.32 0.32 0.46 0.50 0.81 Matched[2875]
YIL070C MAM33 Acidic protein of the mitochondrial matrix involved in oxidative phosphorylation; related to the human complement receptor gC1q-R Verified chr9:230269-231069 230269-231069 99.1% 416.81 371.48 484.81 454.59 402.96 255.63 394.14 469.70 329.29 1.45 1.91 1.36 -0.51 -0.33 Matched[2876]
YIL069C RPS24B Protein component of the small (40S) ribosomal subunit; identical to Rps24Ap and has similarity to rat S24 ribosomal protein Verified chr9:231550-232366 231550-231954,232364-232366 32.2% 3216.73 2327.00 2365.02 1665.40 334.60 83.65 2771.86 2015.21 209.13 10.23 8.18 0.87 -3.27 -2.63 Frag>80[2877,2878]
YIL068W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr9:233010-233393 233010-233393 99.5% 188.46 162.29 151.82 136.11 371.69 204.17 175.37 143.96 287.93 0.65 0.58 1.19 1.00 NaN Frag<80[2879]
YIL068C SEC6 "Essential 88kDa subunit of the exocyst complex, which mediates polarized targeting of secretory vesicles to active sites of exocytosis; dimeric form of Sec6p interacts with Sec9p in vitro and inhibits t-SNARE assembly" Verified chr9:233054-235471 233054-235471 99.4% 124.41 139.80 116.92 101.11 187.24 140.22 132.11 109.01 163.73 0.49 0.44 0.68 0.59 0.72 Frag>80[2879,2880]
YIL066W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr9:237363-237806 237363-237806 99.4% 38.54 31.74 27.20 45.34 31.74 22.67 35.14 36.27 27.20 0.13 0.15 0.11 -0.42 NaN Covered/w/another[2881]
YIL067C Uncharacterized protein of unknown function Uncharacterized chr9:235721-237757 235721-237757 99.0% 69.43 69.93 81.83 57.53 67.94 44.14 69.68 69.68 56.04 0.26 0.28 0.23 -0.31 0.21 Matched[2881]
YIL066C RNR3 "Ribonucleotide-diphosphate reductase (RNR), large subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits" Verified chr9:238096-240705 238096-240705 97.2% 11.82 65.81 15.37 10.25 15.76 27.19 38.81 12.81 21.48 0.14 0.05 0.09 0.75 1.02
YIL065C FIS1 "Mitochondrial outer membrane protein involved in membrane fission, required for localization of Dnm1p and Mdv1p during mitochondrial division; mediates ethanol-induced apoptosis and ethanol-induced mitochondrial fragmentation" Verified chr9:241305-241772 241305-241772 98.9% 293.90 304.70 224.74 188.01 654.78 505.67 299.30 206.37 580.23 1.10 0.84 2.40 1.49 0.72 Matched[2882]
YIL064W Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family Uncharacterized chr9:241940-242713 241940-242713 98.3% 158.97 65.69 88.02 76.20 26.28 11.82 112.33 82.11 19.05 0.41 0.33 0.08 -2.11 -1.55 Frag>80[2883,2884]
YIL063C YRB2 "Protein of unknown function involved in nuclear processes of the Ran-GTPase cycle; involved in nuclear protein export; contains Ran Binding Domain and FxFG repeats; interacts with Srm1p, GTP-Gsp1p, Rna1p and Crm1p; is not essential" Verified chr9:242758-243741 242758-243741 99.5% 275.87 270.77 304.48 293.24 521.09 384.18 273.32 298.86 452.64 1.01 1.21 1.88 0.60 0.37 Matched[2885]
YIL062C ARC15 "Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches" Verified chr9:243995-244459 243995-244459 98.9% 624.25 704.73 776.51 654.70 1559.54 967.92 664.49 715.61 1263.73 2.45 2.90 5.24 0.82 0.79 Matched[2886]
YIL061C SNP1 Component of U1 snRNP required for mRNA splicing via spliceosome; may interact with poly(A) polymerase to regulate polyadenylation; homolog of human U1 70K protein Verified chr9:244654-245556 244654-245556 98.9% 75.03 80.63 59.35 45.91 30.24 23.52 77.83 52.63 26.88 0.29 0.21 0.11 -0.97 0.71 Matched[2887]
YIL060W Putative protein of unknown function; mutant accumulates less glycogen than does wild type; YIL060W is not an essential gene Uncharacterized chr9:246389-246823 246389-246823 63.0% 105.90 314.06 109.56 105.90 160.68 65.73 209.98 107.73 113.21 0.78 0.44 0.47 0.07 0.14 Frag<80[2888]
YIL058W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr9:246911-247195 246911-247195 98.9% 42.55 117.02 53.19 53.19 28.37 21.28 79.79 53.19 24.82 0.29 0.22 0.10 -1.10 0.12 Frag>80[2888,2889]
YIL059C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YIL060W" Dubious chr9:246547-246912 246547-246912 91.0% 90.05 291.15 108.05 87.04 147.07 54.03 190.60 97.55 100.55 0.70 0.40 0.42 0.04 0.21 Matched[2888]
YIL057C Putative protein of unknown function; expression induced under carbon limitation and repressed under high glucose Uncharacterized chr9:247899-248393 247899-248393 99.2% 2.04 10.18 4.07 6.11 4.07 18.33 6.11 5.09 11.20 0.02 0.02 0.05 1.14 0.78
YIL056W VHR1 "Transcriptional activator, required for the vitamin H-responsive element (VHRE) mediated induction of VHT1 (Vitamin H transporter) and BIO5 (biotin biosynthesis intermediate transporter) in response to low biotin concentrations" Verified chr9:249989-251911 249989-251911 99.0% 125.49 100.29 119.71 92.94 109.21 126.01 112.89 106.32 117.61 0.42 0.43 0.49 0.15 0.86 Matched[2890]
YIL055C Putative protein of unknown function Uncharacterized chr9:252040-253923 252040-253923 98.7% 34.43 39.28 38.20 35.51 169.48 173.25 36.86 36.86 171.37 0.14 0.15 0.71 2.22 2.28 Matched[2891]
YIL054W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr9:254541-254858 254541-254858 99.2% 12.67 0.00 0.00 3.17 12.67 12.67 6.34 1.58 12.67 0.02 0.01 0.05 3.00 1.07 Matched[2892]
YIL053W RHR2 "Constitutively expressed isoform of DL-glycerol-3-phosphatase; involved in glycerol biosynthesis, induced in response to both anaerobic and, along with the Hor2p/Gpp2p isoform, osmotic stress" Verified chr9:255113-255865 255113-255865 96.6% 4872.34 3336.24 3700.66 2643.14 891.13 434.56 4104.29 3171.90 662.85 15.15 12.88 2.75 -2.26 -2.66 Matched[2893]
YIL052C RPL34B "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl34Ap and has similarity to rat L34 ribosomal protein" Verified chr9:256224-257061 256224-256552,257025-257061 75.9% 7731.25 6475.10 6457.11 5737.25 1691.66 1576.48 7103.18 6097.18 1634.07 26.22 24.75 6.77 -1.90 -2.55 Frag>80[2894,2895,2896]
YIL051C MMF1 Mitochondrial protein involved in maintenance of the mitochondrial genome Verified chr9:257842-258279 257842-258279 98.7% 2305.65 2564.66 2421.28 2532.28 4997.49 3563.69 2435.15 2476.78 4280.59 8.99 10.05 17.74 0.79 0.29 Matched[2897]
YIL050W PCL7 "Pho85p cyclin of the Pho80p subfamily, forms a functional kinase complex with Pho85p which phosphorylates Mmr1p and is regulated by Pho81p; involved in glycogen metabolism, expression is cell-cycle regulated" Verified chr9:258912-259769 258912-259769 98.9% 166.18 144.97 126.11 149.68 297.01 192.11 155.58 137.90 244.56 0.57 0.56 1.01 0.83 1.06 Frag>80[2898,2899]
YIL049W DFG10 "Protein of unknown function, involved in filamentous growth" Verified chr9:260157-260918 260157-260918 99.5% 139.85 114.78 100.27 76.52 109.50 48.82 127.32 88.40 79.16 0.47 0.36 0.33 -0.16 -0.59 Covered/w/another[2900]
YIL048W NEO1 Putative aminophospholipid translocase (flippase) involved in endocytosis and vacuolar biogenesis; localizes to endosomes and the Golgi aparatus Verified chr9:261436-264891 261436-264891 99.1% 106.85 116.49 104.52 97.51 91.38 76.20 111.67 101.01 83.79 0.41 0.41 0.35 -0.27 -0.17
YIL047C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr9:265098-265466 265098-265466 98.5% 844.47 990.26 429.11 319.08 280.57 165.04 917.36 374.10 222.81 3.39 1.52 0.92 -0.75 NaN Covered/w/another[2901]
YIL047C SYG1 Plasma membrane protein of unknown function; truncation and overexpression suppresses lethality of G-alpha protein deficiency Verified chr9:265114-267822 265114-267822 98.7% 396.19 467.65 206.89 162.74 106.25 101.39 431.92 184.81 103.82 1.59 0.75 0.43 -0.83 -0.58 Matched[2901]
YIL046W-A Putative protein of unknown function; identified by expression profiling and mass spectrometry Uncharacterized chr9:268308-268472 268308-268472 98.3% 18.50 6.17 0.00 12.34 18.50 43.18 12.34 6.17 30.84 0.05 0.03 0.13 2.32 NaN Covered/w/another[2902]
YIL046W MET30 "F-box protein containing five copies of the WD40 motif, controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus" Verified chr9:268650-270572 268650-270572 98.2% 94.75 112.22 83.10 71.46 82.04 77.81 103.48 77.28 79.93 0.38 0.31 0.33 0.05 -0.04 Matched[2902]
YIL045W PIG2 Putative type-1 protein phosphatase targeting subunit that tethers Glc7p type-1 protein phosphatase to Gsy2p glycogen synthase Verified chr9:271160-272776 271160-272776 98.8% 80.74 227.21 142.09 148.97 450.67 447.54 153.98 145.53 449.10 0.57 0.59 1.86 1.63 1.68 Matched[2903]
YIL044C AGE2 "ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector, involved in Trans-Golgi-Network (TGN) transport; contains C2C2H2 cysteine/histidine motif" Verified chr9:272949-273845 272949-273845 98.9% 295.28 314.44 247.95 251.33 209.63 156.66 304.86 249.64 183.14 1.13 1.01 0.76 -0.45 -0.08 Matched[2904]
YIL043C CBR1 "Microsomal cytochrome b reductase, not essential for viability; also detected in mitochondria; mutation in conserved NADH binding domain of the human ortholog results in type I methemoglobinemia" Verified chr9:274071-274925 274071-274925 98.7% 1139.42 1416.57 1043.48 1159.55 883.58 785.27 1277.99 1101.52 834.43 4.72 4.47 3.46 -0.40 -0.11 Matched[2905]
YIL042C PKP1 "Mitochondrial kinase, phosphorylates pyruvate dehydrogenase alpha subunit Pda1p" Verified chr9:275107-276291 275107-276291 98.6% 83.00 113.80 98.40 77.87 113.80 89.85 98.40 88.13 101.83 0.36 0.36 0.42 0.21 0.41 Matched[2906]
YIL041W GVP36 "Golgi vesicle protein of unknown function; localizes to both early and late Golgi vesicles; may interact with ribosomes, based on co-purification experiments" Verified chr9:276524-277504 276524-277504 98.4% 981.05 881.60 886.78 869.17 891.96 712.74 931.32 877.97 802.35 3.44 3.56 3.32 -0.13 0.27 Matched[2907]
YIL040W APQ12 Protein involved in nucleocytoplasmic transport of mRNA Verified chr9:277722-278138 277722-278138 99.3% 350.03 306.58 345.20 263.13 323.48 125.53 328.30 304.16 224.50 1.21 1.23 0.93 -0.44 -0.83 Matched[2908]
YIL039W TED1 Conserved phosphoesterase domain-containing protein that acts together with Emp24p/Erv25p in cargo exit from the ER; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) Uncharacterized chr9:278425-279846 278425-279846 98.8% 382.29 373.03 377.30 373.03 208.58 165.87 377.66 375.17 187.23 1.39 1.52 0.78 -1.00 -0.57 Matched[2909]
YIL038C NOT3 "Subunit of the CCR4-NOT complex, which is a global transcriptional regulator with roles in transcription initiation and elongation and in mRNA degradation" Verified chr9:280141-282651 280141-282651 99.2% 227.73 195.20 200.02 178.73 134.95 130.13 211.47 189.38 132.54 0.78 0.77 0.55 -0.51 0.00 Frag>80[2910,2911]
YIL037C PRM2 "Pheromone-regulated protein, predicted to have 4 transmembrane segments and a coiled coil domain; regulated by Ste12p" Verified chr9:283028-284998 283028-284998 99.2% 29.16 34.28 25.07 16.37 26.09 15.86 31.72 20.72 20.97 0.12 0.08 0.09 0.02 -0.14
YIL036W CST6 "Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, activates transcription of genes involved in utilization of non-optimal carbon sources; involved in telomere maintenance" Verified chr9:285665-287428 285665-287428 98.8% 162.32 180.10 209.35 217.38 358.48 279.33 171.21 213.37 318.91 0.63 0.87 1.32 0.58 0.66 Matched[2912]
YIL035C CKA1 "Alpha catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA2, CKB1 and CKB2, the many substrates include transcription factors and all RNA polymerases" Verified chr9:287789-288907 287789-288907 99.4% 566.55 498.20 500.00 427.16 484.71 324.64 532.37 463.58 404.68 1.97 1.88 1.68 -0.20 -0.06 Matched[2913]
YIL034C CAP2 Beta subunit of the capping protein (CP) heterodimer (Cap1p and Cap2p) which binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches Verified chr9:289225-290088 289225-290088 98.7% 650.52 702.09 621.22 668.10 1121.70 966.99 676.30 644.66 1044.34 2.50 2.62 4.33 0.70 0.97 Frag>80[2914,2915]
YIL033C BCY1 "Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA), a component of a signaling pathway that controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation" Verified chr9:290418-291668 290418-291668 98.7% 352.32 422.79 460.85 496.49 900.65 765.39 387.55 478.67 833.02 1.43 1.94 3.45 0.80 1.33 Matched[2916]
YIL032C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr9:291960-292316 291960-292316 98.5% 5.69 14.22 11.37 8.53 14.22 14.22 9.95 9.95 14.22 0.04 0.04 0.06 0.51 0.84
YIL031W ULP2 "Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins, plays a role in chromosome cohesion at centromeric regions and recovery from checkpoint arrest induced by DNA damage or DNA replication defects; potential Cdc28p substrate" Verified chr9:292632-295736 292632-295736 99.0% 120.63 116.73 100.15 97.22 98.20 112.18 118.68 98.68 105.19 0.44 0.40 0.44 0.09 0.57 Covered/w/another[2917]
YIL030W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YIL031W." Dubious chr9:295564-295902 295564-295902 98.9% 152.05 184.84 116.27 110.31 166.96 113.29 168.45 113.29 140.12 0.62 0.46 0.58 0.31 NaN Covered/w/another[2917]
YIL029W-A "Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr9:299734-300105 299734-300105 99.1% 54.27 70.55 51.55 56.98 29.85 51.55 62.41 54.27 40.70 0.23 0.22 0.17 -0.42 NaN Covered[2918]
YIL030C SSM4 "Ubiquitin-protein ligase of the ER/nuclear envelope, required for degradation of Alpha2p and other proteins containing a Deg1 degradation signal; ssm4 mutation suppresses mRNA instability caused by an rna14 mutation" Verified chr9:296049-300008 296049-300008 99.0% 167.57 126.00 135.43 98.96 70.14 53.05 146.78 117.20 61.60 0.54 0.48 0.26 -0.93 -0.82 Frag<80[2918]
YIL029C Putative protein of unknown function; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) Uncharacterized chr9:300827-301255 300827-301255 97.9% 57.15 95.26 78.59 57.15 216.71 133.36 76.21 67.87 175.03 0.28 0.28 0.73 1.37 0.56 Frag>80[2919,2920]
YIL028W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr9:302098-302496 302098-302496 98.9% 22.82 25.35 12.68 12.68 27.89 20.28 24.09 12.68 24.09 0.09 0.05 0.10 0.93 0.96 Covered[2921]
YIL027C KRE27 Protein of unknown function; null mutant shows K1 killer toxin resistance Verified chr9:303677-304102 303677-304102 99.1% 575.55 506.86 468.96 409.75 523.44 267.64 541.20 439.36 395.54 2.00 1.78 1.64 -0.15 -0.67 Matched[2922]
YIL026C IRR1 "Subunit of the cohesin complex, which is required for sister chromatid cohesion during mitosis and meiosis and interacts with centromeres and chromosome arms, essential for viability" Verified chr9:304475-307927 304475-307927 99.1% 111.29 95.52 98.15 103.11 55.79 49.95 103.40 100.63 52.87 0.38 0.41 0.22 -0.93 -0.31 Matched[2923]
YIL025C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr9:308199-308573 308199-308573 99.0% 8.08 5.39 5.39 5.39 10.77 13.47 6.73 5.39 12.12 0.02 0.02 0.05 1.17 0.00 Overlap[2924]
YIL024C Putative protein of unknown function; non-essential gene; expression directly regulated by the metabolic and meiotic transcriptional regulator Ume6p Uncharacterized chr9:308600-309169 308600-309169 99.0% 58.48 47.85 62.03 31.90 104.56 33.67 53.17 46.96 69.12 0.20 0.19 0.29 0.56 0.91 Matched[2924]
YIL023C YKE4 "Zinc transporter; localizes to the ER; null mutant is sensitive to calcofluor white, leads to zinc accumulation in cytosol; ortholog of the mouse KE4 and member of the ZIP (ZRT, IRT-like Protein) family" Verified chr9:309384-310424 309384-310424 98.3% 152.39 127.97 165.09 154.34 290.12 185.60 140.18 159.71 237.86 0.52 0.65 0.99 0.57 0.42 Matched[2925]
YIL022W TIM44 "Peripheral mitochondrial membrane protein involved in mitochondrial protein import, tethers essential chaperone Ssc1p to the translocon channel at the matrix side of the inner membrane" Verified chr9:311163-312458 311163-312458 98.0% 335.33 357.37 346.35 334.55 292.04 310.93 346.35 340.45 301.49 1.28 1.38 1.25 -0.18 0.21 Matched[2926]
YIL021W RPB3 "RNA polymerase II third largest subunit B44, part of central core; similar to prokaryotic alpha subunit" Verified chr9:312903-313859 312903-313859 98.5% 447.73 406.35 421.20 368.15 253.57 179.30 427.04 394.68 216.44 1.58 1.60 0.90 -0.87 -0.77 Matched[2927]
YIL021C-A "Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps verified gene RPB3/YIL021W; identified by gene-trapping, expression analysis, and genome-wide homology searching" Dubious chr9:313197-313466 313197-313466 98.4% 478.12 372.71 402.82 338.82 244.71 154.35 425.41 370.82 199.53 1.57 1.51 0.83 -0.89 NaN Matched[2927]
YIL020C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr9:313711-314049 313711-314049 98.1% 459.92 411.82 426.85 342.69 282.57 204.41 435.87 384.77 243.49 1.61 1.56 1.01 -0.66 NaN
YIL020C HIS6 "Phosphoribosyl-5-amino-1-phosphoribosyl-4-imidazolecarboxiamide isomerase, catalyzes the fourth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts" Verified chr9:314033-314818 314033-314818 99.4% 195.74 106.18 102.35 71.64 93.39 126.65 150.96 86.99 110.02 0.56 0.35 0.46 0.34 -0.16 Matched[2928]
YIL019W FAF1 Protein required for pre-rRNA processing and 40S ribosomal subunit assembly Verified chr9:315091-316131 315091-316131 98.1% 133.18 46.02 62.67 40.15 9.79 5.88 89.60 51.41 7.83 0.33 0.21 0.03 -2.71 -2.47 Matched[2929]
YIL018W RPL2B "Protein component of the large (60S) ribosomal subunit, identical to Rpl2Ap and has similarity to E. coli L2 and rat L8 ribosomal proteins; expression is upregulated at low temperatures" Verified chr9:316766-317930 316766-316769,317170-317930 41.4% 11543.38 9242.92 9862.28 8411.85 2338.38 2648.06 10393.15 9137.06 2493.22 38.37 37.09 10.33 -1.87 -2.49 Frag>80[2930,2931,2932]
YIL017C VID28 "Protein involved in proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBPase); localized to the nucleus and the cytoplasm" Verified chr9:318198-320963 318198-320963 99.2% 79.79 121.33 106.02 110.03 150.47 140.27 100.56 108.03 145.37 0.37 0.44 0.60 0.43 0.57 Matched[2933]
YIL016W SNL1 Protein of unknown function proposed to be involved in nuclear pore complex biogenesis and maintenance as well as protein folding; has similarity to the mammalian BAG-1 protein Verified chr9:321452-321931 321452-321931 98.3% 366.75 224.72 290.43 235.31 205.64 97.52 295.73 262.87 151.58 1.09 1.07 0.63 -0.79 -0.99 Frag>80[2934,2935]
YIL015W BAR1 "Aspartyl protease secreted into the periplasmic space of mating type a cells, helps cells find mating partners, cleaves and inactivates alpha factor allowing cells to recover from alpha-factor-induced cell cycle arrest" Verified chr9:322340-324103 322340-324103 99.0% 650.60 803.51 675.80 585.31 336.18 156.92 727.06 630.55 246.55 2.68 2.56 1.02 -1.35 -1.29 Matched[2936]
YIL014C-A Putative protein of unknown function Uncharacterized chr9:325210-325524 325210-325524 99.1% 208.25 246.70 217.86 214.66 438.93 253.10 227.47 216.26 346.02 0.84 0.88 1.43 0.68 -0.13 Matched[2938]
YIL014W MNT3 "Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-linked glycans during protein O-glycosylation" Verified chr9:326101-327993 326101-327993 98.7% 170.68 154.10 154.63 130.02 138.58 83.47 162.39 142.33 111.02 0.60 0.58 0.46 -0.36 -0.50 Matched[2939]
YIL013C PDR11 "ATP-binding cassette (ABC) transporter, multidrug transporter involved in multiple drug resistance; mediates sterol uptake when sterol biosynthesis is compromisedregulated by Pdr1p; required for anaerobic growth" Verified chr9:328205-332440 328205-332440 98.8% 36.33 47.56 23.90 18.88 26.77 24.14 41.94 21.39 25.45 0.15 0.09 0.11 0.25 0.81 Frag<80[2940]
YIL012W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr9:333009-333401 333009-333401 98.3% 7.77 2.59 5.18 0.00 10.35 12.94 5.18 2.59 11.65 0.02 0.01 0.05 2.17 0.76 Frag<80[2941]
YIL011W TIR3 Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth Verified chr9:333724-334533 333724-334533 94.2% 149.34 584.28 180.79 167.69 61.57 77.29 366.81 174.24 69.43 1.35 0.71 0.29 -1.33 -0.01 Frag>80[2941,2942,2943]
YIL010W DOT5 Nuclear thiol peroxidase which functions as an alkyl-hydroperoxide reductase during post-diauxic growth Verified chr9:334879-335526 334879-335526 98.6% 286.31 347.33 303.52 281.62 378.62 280.05 316.82 292.57 329.34 1.17 1.19 1.36 0.17 0.40 Matched[2944]
YIL009C-A EST3 "Component of the telomerase holoenzyme, involved in telomere replication" Verified chr9:335663-336209 335663-336209 99.0% 151.41 219.73 168.03 149.56 210.49 199.42 185.57 158.79 204.95 0.69 0.64 0.85 0.37 0.78 Matched[2945]
YIL009W FAA3 "Long chain fatty acyl-CoA synthetase, has a preference for C16 and C18 fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery" Verified chr9:339341-341425 339341-341425 97.9% 234.57 207.15 196.86 171.89 107.74 99.41 220.86 184.37 103.57 0.82 0.75 0.43 -0.83 -0.24 Matched[2947]
YIL008W URM1 "Ubiquitin-like protein with weak sequence similarity to ubiquitin; depends on the E1-like activating enzyme Uba4p; molecular function of the Urm1p pathway is unknown, but it is required for normal growth, particularly at high temperature" Verified chr9:342533-342832 342533-342832 98.8% 371.26 199.13 273.38 300.38 172.13 94.50 285.19 286.88 133.31 1.05 1.16 0.55 -1.11 -1.38 Matched[2948]
YIL007C NAS2 Protein with similarity to the p27 subunit of mammalian proteasome modulator; not essential; interacts with Rpn4p Verified chr9:342991-343653 342991-343653 99.2% 95.81 98.85 106.46 80.60 267.66 194.66 97.33 93.53 231.16 0.36 0.38 0.96 1.31 1.04 Matched[2949]
YIL006W YIA6 "Mitochondrial NAD+ transporter, involved in the transport of NAD+ into the mitochondria (see also YEA6); member of the mitochondrial carrier subfamily; disputed role as a pyruvate transporter; has putative mouse and human orthologs" Verified chr9:344059-345180 344059-345180 98.8% 66.75 67.65 56.83 67.65 99.22 78.48 67.20 62.24 88.85 0.25 0.25 0.37 0.51 1.17 Matched[2950]
YIL005W EPS1 "ER protein with chaperone and co-chaperone activity, involved in retention of resident ER proteins; has a role in recognizing proteins targeted for ER-associated degradation (ERAD), member of the protein disulfide isomerase family" Verified chr9:345689-347794 345689-347794 98.8% 247.58 266.32 246.13 246.61 177.39 178.35 256.95 246.37 177.87 0.95 1.00 0.74 -0.47 -0.15 Frag>80[2951,2952]
YIL004C BET1 Type II membrane protein required for vesicular transport between the endoplasmic reticulum and Golgi complex; v-SNARE with similarity to synaptobrevins Verified chr9:347943-348502 347943-348360,348492-348502 99.2% 213.74 183.21 204.35 173.81 251.32 166.76 198.47 189.08 209.04 0.73 0.77 0.87 0.14 -0.44 Matched[2952]
YIL003W CFD1 "Highly conserved, iron-sulfur cluster binding protein localized in the cytoplasm; forms a complex with Nbp35p that is involved in iron-sulfur protein assembly in the cytosol" Verified chr9:349119-350000 349119-350000 98.6% 146.03 86.24 93.13 70.14 71.29 33.34 116.13 81.64 52.32 0.43 0.33 0.22 -0.64 -0.72 Matched[2953]
YIL002W-A Putative protein of unknown function; identified by expression profiling and mass spectrometry Uncharacterized chr9:350298-350507 350298-350507 98.1% 834.95 723.30 723.30 674.76 868.93 606.80 779.13 699.03 737.86 2.88 2.84 3.06 0.08 NaN Matched[2954]
YIL002C INP51 "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in phosphatidylinositol 4,5-bisphosphate homeostasis and in endocytosis; null mutation confers cold-tolerant growth" Verified chr9:350588-353428 350588-353428 99.2% 110.68 113.16 89.75 88.68 111.39 89.39 111.92 89.22 100.39 0.41 0.36 0.42 0.17 0.30 Frag>80[2954,2955]
YIL001W Hypothetical protein Uncharacterized chr9:353937-355478 353937-355478 98.8% 51.84 66.93 51.84 36.75 76.12 51.84 59.38 44.29 63.98 0.22 0.18 0.27 0.53 0.21 Matched[2956]
YIR001C SGN1 "Cytoplasmic RNA-binding protein, contains an RNA recognition motif (RRM); may have a role in mRNA translation, as suggested by genetic interactions with genes encoding proteins involved in translational initiation" Verified chr9:356140-356892 356140-356892 98.9% 240.44 280.74 249.85 229.70 229.70 193.43 260.59 239.77 211.56 0.96 0.97 0.88 -0.18 0.27 Matched[2958]
YIR002C MPH1 "Member of the DEAH family of helicases, functions in an error-free DNA damage bypass pathway that involves homologous recombination, mutations confer a mutator phenotype" Verified chr9:357412-360393 357412-360393 99.4% 84.71 90.11 72.56 66.82 136.68 111.03 87.41 69.69 123.86 0.32 0.28 0.51 0.83 1.12 Matched[2960]
YIR003W "Protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein colocalizes with Sac1p to the actin cytoskeleton; interacts with with the SH3 domain of Abp1p" Verified chr9:360882-362921 360882-362921 98.3% 149.53 163.99 151.53 140.56 207.85 218.32 156.76 146.04 213.08 0.58 0.59 0.88 0.55 0.94 Matched[2961]
YIR004W DJP1 "Cytosolic J-domain-containing protein, required for peroxisomal protein import and involved in peroxisome assembly, homologous to E. coli DnaJ" Verified chr9:363218-364516 363218-364516 98.2% 331.52 263.33 293.90 263.33 289.19 194.36 297.42 278.61 241.78 1.10 1.13 1.00 -0.20 -0.11 Matched[2962]
YIR005W IST3 "Component of the U2 snRNP, required for the first catalytic step of splicing and for spliceosomal assembly; interacts with Rds3p and is required for Mer1p-activated splicing" Verified chr9:364886-365332 364886-365332 98.7% 81.59 104.26 68.00 79.33 140.52 88.39 92.93 73.66 114.46 0.34 0.30 0.47 0.64 0.13 Matched[2963]
YIR006C PAN1 "Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p, associates with actin patches on the cell cortex; promotes protein-protein interactions essential for endocytosis; previously thought to be a subunit of poly(A) ribonuclease" Verified chr9:365463-369905 365463-369905 96.2% 312.23 381.04 329.78 347.33 190.99 408.42 346.63 338.56 299.70 1.28 1.37 1.24 -0.18 0.70 Matched[2964]
YIR007W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YIR007W is a non-essential gene Uncharacterized chr9:370701-372995 370701-372995 98.8% 64.82 103.18 75.40 56.44 110.24 115.09 84.00 65.92 112.66 0.31 0.27 0.47 0.77 1.12 Covered/w/another[2965]
YIR008C PRI1 "Subunit of DNA primase, which is required for DNA synthesis and double-strand break repair" Verified chr9:373074-374303 373074-374303 99.1% 129.62 133.72 132.08 117.31 109.93 81.22 131.67 124.70 95.57 0.49 0.51 0.40 -0.38 0.18 Covered/w/another[2965]
YIR009W MSL1 "U2B component of U2 snRNP, involved in splicing, binds the U2 snRNA stem-loop IV in vitro; does not contain the conserved C-terminal RNA binding domain found in other family members" Verified chr9:374522-374857 374522-374857 98.5% 81.61 96.73 96.73 114.86 105.79 84.63 89.17 105.79 95.21 0.33 0.43 0.39 -0.15 0.22 Matched[2966]
YIR010W DSN1 Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; important for chromosome segregation Verified chr9:375428-377158 375428-377158 97.4% 144.71 133.44 108.53 114.46 190.37 145.89 139.07 111.50 168.13 0.51 0.45 0.70 0.59 0.63 Covered/w/another[2967]
YIR011C STS1 Protein that interacts with the karyopherin Srp1p; may have a role with Srp1p in ubiquitin-mediated protein degradation Verified chr9:377284-378243 377284-378243 99.3% 215.10 192.02 183.62 178.38 207.76 151.10 203.56 181.00 179.43 0.75 0.73 0.74 -0.01 0.11 Covered/w/another[2967]
YIR012W SQT1 Essential protein involved in a late step of 60S ribosomal subunit assembly or modification; contains multiple WD repeats; interacts with Qsr1p in a two-hybrid assay Verified chr9:378483-379778 378483-379778 98.6% 305.31 223.90 241.90 170.66 81.42 62.63 264.61 206.28 72.02 0.98 0.84 0.30 -1.52 -1.49 Frag>80[2968,2969]
YIR013C GAT4 Protein containing GATA family zinc finger motifs Verified chr9:380016-380381 380016-380381 98.8% 8.29 8.29 0.00 0.00 8.29 13.82 8.29 0.00 11.06 0.03 0.00 0.05 Inf 0.26 Frag<80[2969,2970]
YIR014W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; expression directly regulated by the metabolic and meiotic transcriptional regulator Ume6p; YIR014W is a non-essential gene Uncharacterized chr9:381083-381811 381083-381811 98.6% 62.60 93.20 66.77 84.85 166.93 239.26 77.90 75.81 203.10 0.29 0.31 0.84 1.42 1.91 Matched[2971]
YIR015W RPR2 "Subunit of nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; not shared between RNase MRP and RNase P, in contrast to all other RNase P protein subunits" Verified chr9:381945-382379 381945-382379 98.6% 116.57 109.58 111.91 109.58 200.51 261.12 113.08 110.74 230.81 0.42 0.45 0.96 1.06 1.65 Covered/w/another[2971]
YIR016W Putative protein of unknown function; expression directly regulated by the metabolic and meiotic transcriptional regulator Ume6p; YIR016W is a non-essential gene Uncharacterized chr9:382625-383422 382625-383422 98.4% 221.56 420.20 468.59 550.08 918.08 644.31 320.88 509.34 781.20 1.18 2.07 3.24 0.62 0.64 Matched[2972]
YIR017W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr9:383563-384162 383563-384162 99.2% 25.19 89.00 43.66 45.34 193.12 109.15 57.09 44.50 151.13 0.21 0.18 0.63 1.76 NaN Frag>80[2973,2974]
YIR017C MET28 "Transcriptional activator in the Cbf1p-Met4p-Met28p complex, participates in the regulation of sulfur metabolism" Verified chr9:383553-384116 383553-384116 99.2% 30.38 94.71 50.04 50.04 203.72 114.37 62.55 50.04 159.05 0.23 0.20 0.66 1.67 1.06 Frag>80[2973,2974]
YIR018W YAP5 Basic leucine zipper (bZIP) transcription factor Verified chr9:384606-385343 384606-385343 98.5% 63.27 74.27 49.52 70.15 126.54 116.91 68.77 59.83 121.73 0.25 0.24 0.50 1.02 0.99 Matched[2975]
YIR018C-A Putative protein of unknown function; identified by expression profiling and mass spectrometry Uncharacterized chr9:385561-385698 385561-385698 98.9% 73.30 80.64 51.31 43.98 102.63 58.64 76.97 47.65 80.64 0.28 0.19 0.33 0.76 NaN Covered/w/another[2975]
YIR019C MUC1 "GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)" Verified chr9:389569-393672 389569-393672 54.8% 30.67 58.23 33.34 21.78 9.78 8.45 44.45 27.56 9.11 0.16 0.11 0.04 -1.60 -0.27 Frag<80[2978]
YIR020C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr9:394252-394554 394252-394554 99.0% 66.68 80.01 23.34 80.01 100.01 76.68 73.34 51.67 88.35 0.27 0.21 0.37 0.77 0.65 Covered/w/another[2979]
YIR020W-A "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data" Dubious chr9:394914-395156 394914-395156 98.7% 25.02 29.19 33.36 58.38 45.87 45.87 27.11 45.87 45.87 0.10 0.19 0.19 0.00 NaN Covered/w/another[2979]
YIR021W MRS1 "Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA" Verified chr9:397291-398382 397291-398382 98.8% 155.69 146.43 146.43 122.33 85.26 64.87 151.06 134.38 75.07 0.56 0.55 0.31 -0.84 -0.60 Frag>80[2980,2981]
YIR020C-B "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF MRS1" Dubious chr9:397212-397946 397212-397946 98.8% 121.15 108.76 118.40 97.75 70.21 42.68 114.95 108.07 56.44 0.42 0.44 0.23 -0.94 NaN Matched[2980]
YIR021W-A Putative protein of unknown function; identified by expression profiling and mass spectrometry Uncharacterized chr9:398511-398723 398511-398723 98.6% 47.63 61.92 85.73 76.21 80.97 66.68 54.77 80.97 73.82 0.20 0.33 0.31 -0.13 NaN Frag<80[2981,2982]
YIR022W SEC11 "18kDa catalytic subunit of the Signal Peptidase Complex (SPC; Spc1p, Spc2p, Spc3p, and Sec11p) which cleaves the signal sequence of proteins targeted to the endoplasmic reticulum" Verified chr9:398730-399233 398730-399233 98.6% 511.15 537.31 595.67 579.57 525.24 503.10 524.23 587.62 514.17 1.94 2.39 2.13 -0.19 -0.06 Matched[2982]
YIR023W DAL81 Positive regulator of genes in multiple nitrogen degradation pathways; contains DNA binding domain but does not appear to bind the dodecanucleotide sequence present in the promoter region of many genes involved in allantoin catabolism Verified chr9:399774-402686 399774-402686 98.4% 123.15 111.98 85.82 95.94 45.35 63.49 117.56 90.88 54.42 0.43 0.37 0.23 -0.74 0.18 Covered/w/another[2983]
YIR023C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr9:402380-402703 402380-402703 98.5% 147.22 187.94 156.62 156.62 78.31 78.31 167.58 156.62 78.31 0.62 0.64 0.32 -1.00 NaN Covered/w/another[2983]
YIR024C "Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; interacts with Arh1p, a mitochondrial oxidoreductase; deletion mutant has a respiratory growth defect" Verified chr9:402838-403488 402838-403488 99.6% 87.91 78.66 111.05 94.08 209.76 118.76 83.29 102.56 164.26 0.31 0.42 0.68 0.68 0.77 Covered/w/another[2983]
YIR025W MND2 Subunit of the anaphase-promoting complex (APC); needed for meiotic nuclear division Verified chr9:403656-404762 403656-404762 98.2% 37.70 41.38 39.54 24.83 68.97 51.50 39.54 32.19 60.23 0.15 0.13 0.25 0.90 0.70 Matched[2984]
YIR026C YVH1 "Protein phosphatase involved in vegetative growth at low temperatures, sporulation, and glycogen accumulation; transcription induced by low temperature and nitrogen starvation; member of the dual-specificity family of protein phosphatases" Verified chr9:404870-405964 404870-405964 98.9% 144.01 75.70 108.93 82.16 21.23 12.92 109.85 95.55 17.08 0.41 0.39 0.07 -2.48 -3.13 Matched[2985]
YIR027C DAL1 "Allantoinase, converts allantoin to allantoate in the first step of allantoin degradation; expression sensitive to nitrogen catabolite repression" Verified chr9:406257-407639 406257-407639 98.9% 7.31 2.19 2.19 2.92 29.98 31.44 4.75 2.56 30.71 0.02 0.01 0.13 3.58 1.24 Matched[2986]
YIR028W DAL4 "Allantoin permease; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation" Verified chr9:408465-410372 408465-410372 98.9% 6.36 4.77 5.83 4.77 6.36 7.95 5.57 5.30 7.16 0.02 0.02 0.03 0.43 1.39 Frag<80[2987]
YIR029W DAL2 "Allantoicase, converts allantoate to urea and ureidoglycolate in the second step of allantoin degradation; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation" Verified chr9:410804-411835 410804-411835 98.4% 26.60 27.59 24.63 36.45 59.11 46.30 27.09 30.54 52.71 0.10 0.12 0.22 0.79 0.90 Matched[2988]
YIR030C DCG1 "Protein of unknown function, expression is sensitive to nitrogen catabolite repression and regulated by Dal80p; contains transmembrane domain" Verified chr9:412033-412767 412033-412767 99.3% 8.22 17.82 19.19 20.56 19.19 5.48 13.02 19.87 12.33 0.05 0.08 0.05 -0.69 -1.43
YIR030W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr9:412896-413279 412896-413279 99.2% 89.27 105.02 47.26 39.38 102.40 31.51 97.14 43.32 66.95 0.36 0.18 0.28 0.63 NaN Covered/w/another[2989]
YIR031C DAL7 "Malate synthase, role in allantoin degradation unknown; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation" Verified chr9:413012-414676 413012-414676 99.1% 69.10 92.73 61.82 42.43 84.85 45.46 80.92 52.13 65.16 0.30 0.21 0.27 0.32 0.53 Matched[2989]
YIR032C DAL3 "Ureidoglycolate hydrolase, converts ureidoglycolate to glyoxylate and urea in the third step of allantoin degradation; expression sensitive to nitrogen catabolite repression" Verified chr9:415027-415614 415027-415614 98.9% 34.38 39.53 17.19 25.78 56.72 55.00 36.95 21.49 55.86 0.14 0.09 0.23 1.38 0.77 Matched[2990]
YIR033W MGA2 "ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Spt23p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting" Verified chr9:416121-419462 416121-419462 98.6% 129.32 389.49 128.72 125.98 95.63 86.82 259.40 127.35 91.22 0.96 0.52 0.38 -0.48 -0.08 Covered/w/another[2991]
YIR034C LYS1 "Saccharopine dehydrogenase (NAD+, L-lysine-forming), catalyzes the conversion of saccharopine to L-lysine, which is the final step in the lysine biosynthesis pathway" Verified chr9:419612-420733 419612-420733 98.7% 262.00 466.18 266.52 226.76 284.58 272.84 364.09 246.64 278.71 1.34 1.00 1.15 0.18 0.59 Covered/w/another[2991]
YIR035C Putative cytoplasmic protein of unknown function Uncharacterized chr9:421023-421787 421023-421787 98.8% 326.67 296.25 227.48 173.25 167.96 93.90 311.46 200.36 130.93 1.15 0.81 0.54 -0.61 -0.52 Matched[2992]
YIR036W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr9:422632-423033 422632-423033 98.8% 125.87 183.76 103.21 105.73 342.35 276.90 154.81 104.47 309.63 0.57 0.42 1.28 1.57 NaN Matched[2993]
YIR036C Putative benzil reductase;(GFP)-fusion protein localizes to the cytoplasm and is induced by the DNA-damaging agent MMS; sequence similarity with short-chain dehydrogenase/reductases; null mutant has increased spontaneous Rad52 foci Uncharacterized chr9:422071-422862 422071-422862 98.5% 257.54 295.98 283.17 246.01 636.81 451.02 276.76 264.59 543.91 1.02 1.07 2.25 1.04 1.34 Matched[2993]
YIR037W HYR1 Thiol peroxidase that functions as a hydroperoxide receptor to sense intracellular hydroperoxide levels and transduce a redox signal to the Yap1p transcription factor Verified chr9:423125-423616 423125-423616 98.5% 1091.75 1461.17 1054.60 1153.67 2230.97 1642.79 1276.46 1104.14 1936.88 4.71 4.48 8.03 0.81 0.68 Covered/w/another[2994]
YIR038C GTT1 "ER associated glutathione S-transferase capable of homodimerization; expression induced during the diauxic shift and throughout stationary phase; functional overlap with Gtt2p, Grx1p, and Grx2p" Verified chr9:423806-424510 423806-424510 98.9% 526.54 879.48 535.15 553.80 1855.09 1439.02 703.01 544.48 1647.06 2.60 2.21 6.82 1.60 1.41 Matched[2994]
YIR039C YPS6 Putative GPI-anchored aspartic protease Verified chr9:430494-432107 430494-432107 76.2% 46.35 81.32 68.31 79.69 556.21 409.84 63.83 74.00 483.03 0.24 0.30 2.00 2.71 2.61 Frag>80[2995]
YIR040C "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data" Dubious chr9:433385-433717 433385-433717 6.2% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.02
YIR041W PAU15 Hypothetical protein Uncharacterized chr9:433925-434299 433925-434299 4.8% 0.00 0.00 0.00 0.00 55.17 0.00 0.00 0.00 27.59 0.00 0.00 0.11 Inf 0.99
YIR042C Putative protein of unknown function; YIR042C is a non-essential gene Uncharacterized chr9:435270-435980 435270-435980 99.4% 107.57 101.90 70.77 50.95 41.04 32.55 104.74 60.86 36.80 0.39 0.25 0.15 -0.73 -0.76 Covered[2996]
YJL225W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the uncharacterized gene YJL225C" Dubious chr10:829-1311 829-1311 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YJL225C Putative protein of unknown function; similarity to DNA helicases that are also encoded within subtelomeric Y' elements and induced in telomerase deficient survivors Uncharacterized chr10:466-6130 466-4581,4970-6130 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.23
YJL223C PAU1 "Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme" Verified chr10:8776-9138 8776-9138 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.66
YJL222W-B "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr10:9346-9483 9346-9483 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YJL222W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr10:9452-9679 9452-9679 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YJL222W VTH2 "Putative membrane glycoprotein with strong similarity to Vth1p and Pep1p/Vps10p, may be involved in vacuolar protein sorting" Verified chr10:11475-16124 11475-16124 0.1% 0.00 0.00 250.00 0.00 0.00 250.00 0.00 125.00 125.00 0.00 0.51 0.52 0.00 0.16
YJL220W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YJL221C/FSP2" Dubious chr10:18243-18695 18243-18695 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.49
YJL221C FSP2 "Protein of unknown function, expression is induced during nitrogen limitation" Verified chr10:16767-18536 16767-18536 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.34
YJL219W HXT9 "Putative hexose transporter that is nearly identical to Hxt11p, has similarity to major facilitator superfamily (MFS) transporters, expression of HXT9 is regulated by transcription factors Pdr1p and Pdr3p" Verified chr10:19497-21200 19497-21200 16.5% 3.55 3.55 3.55 3.55 10.64 0.00 3.55 3.55 5.32 0.01 0.01 0.02 0.58 0.03
YJL218W "Putative protein of unknown function, similar to bacterial galactoside O-acetyltransferases; induced by oleate in an OAF1/PIP2-dependent manner; promoter contains an oleate response element consensus sequence; non-essential gene" Uncharacterized chr10:21973-22563 21973-22563 98.7% 49.74 42.88 29.16 32.59 48.02 20.58 46.31 30.87 34.30 0.17 0.13 0.14 0.15 0.09 Matched[2997]
YJL217W "Cytoplasmic protein of unknown function; expression induced by calcium shortage and via the copper sensing transciption factor Mac1p during conditons of copper deficiency; mRNA is cell cycle regulated, peaking in G1 phase" Uncharacterized chr10:23133-23729 23133-23729 98.6% 285.43 304.12 316.01 314.31 905.56 521.59 294.78 315.16 713.58 1.09 1.28 2.96 1.18 1.17 Frag>80[2998,2999]
YJL216C "Protein of unknown function, similar to alpha-D-glucosidases; transcriptionally activated by both Pdr8p and Yrm1p, along with transporters and other genes involved in the pleiotropic drug resistance (PDR) phenomenon" Uncharacterized chr10:24341-26086 24341-26086 98.4% 29.69 33.18 31.43 31.43 9.31 11.06 31.43 31.43 10.19 0.12 0.13 0.04 -1.63 -1.07 Matched[3000]
YJL215C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr10:26412-26771 26412-26771 98.6% 30.99 28.18 11.27 25.36 16.91 19.72 29.58 18.31 18.31 0.11 0.07 0.08 0.00 -0.07
YJL214W HXT8 "Protein of unknown function with similarity to hexose transporter family members, expression is induced by low levels of glucose and repressed by high levels of glucose" Verified chr10:26887-28596 26887-28596 98.5% 19.59 23.74 16.62 21.96 24.93 20.77 21.66 19.29 22.85 0.08 0.08 0.09 0.24 -0.09 Frag<80[3001]
YJL213W "Protein of unknown function that may interact with ribosomes; periodically expressed during the yeast metabolic cycle; phosphorylated in vitro by the mitotic exit network (MEN) kinase complex, Dbf2p/Mob1p" Verified chr10:32163-33158 32163-33158 98.5% 62.16 158.97 58.08 64.20 243.55 207.88 110.56 61.14 225.71 0.41 0.25 0.94 1.88 1.97 Matched[3003]
YJL212C OPT1 Proton-coupled oligopeptide transporter of the plasma membrane; also transports glutathione and phytochelatin; member of the OPT family Verified chr10:33850-36249 33850-36249 98.6% 99.30 161.83 108.59 89.58 60.85 71.83 130.57 99.09 66.34 0.48 0.40 0.27 -0.58 0.11 Matched[3004]
YJL210W PEX2 "RING-finger peroxin, peroxisomal membrane protein with a C-terminal zinc-binding RING domain, forms translocation subcomplex with Pex10p and Pex12p which functions in peroxisomal matrix protein import" Verified chr10:36919-37734 36919-37734 98.7% 149.06 223.59 218.62 186.33 362.71 186.33 186.33 202.47 274.52 0.69 0.82 1.14 0.44 0.22 Frag>80[3005,3006]
YJL211C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YJL210W/PEX2" Dubious chr10:36757-37200 36757-37200 98.2% 98.64 153.70 135.35 135.35 199.58 110.11 126.17 135.35 154.85 0.47 0.55 0.64 0.19 0.91 Frag<80[3005,3006]
YJL209W CBP1 Mitochondrial protein that interacts with the 5'-untranslated region of the COB mRNA and has a role in its stability and translation; found in a complex at the inner membrane along with Pet309p Verified chr10:38005-39969 38005-39969 98.9% 86.92 91.03 86.40 76.12 74.58 55.03 88.98 81.26 64.80 0.33 0.33 0.27 -0.33 -0.80 Covered/w/another[3007]
YJL208C NUC1 "Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has roles in mitochondrial recombination, apoptosis and maintenance of polyploidy" Verified chr10:40194-41183 40194-41183 98.9% 206.27 124.58 171.55 118.45 37.78 31.66 165.43 145.00 34.72 0.61 0.59 0.14 -2.06 -2.15 Covered/w/another[3007]
YJL207C LAA1 AP-1 accessory protein; colocalizes with clathrin to the late-Golgi apparatus; involved in TGN-endosome transport; physically interacts with AP-1; similar to the mammalian p200; may interact with ribosomes; YJL207C is a non-essential gene Verified chr10:41389-47433 41389-47433 99.2% 138.44 134.60 110.59 109.25 75.06 62.21 136.52 109.92 68.64 0.50 0.45 0.28 -0.68 -1.17 Covered/w/another[3007]
YJL206C "Putative protein of unknown function; similar to transcriptional regulators from the Zn[2]-Cys[6] binuclear cluster protein family; mRNA is weakly cell cycle regulated, peaking in S phase; induced rapidly upon MMS treatment" Uncharacterized chr10:47659-49935 47659-49935 99.1% 33.69 29.70 29.70 28.37 58.51 48.76 31.70 29.04 53.64 0.12 0.12 0.22 0.89 1.43 Covered/w/another[3007]
YJL205C NCE101 "Protein of unknown function, involved in secretion of proteins that lack classical secretory signal sequences" Verified chr10:50139-50443 50139-50268,50412-50443 98.7% 193.90 181.39 187.65 218.92 469.12 293.98 187.65 203.28 381.55 0.69 0.83 1.58 0.91 NaN Covered/w/another[3007]
YJL204C RCY1 F-box protein involved in recycling plasma membrane proteins internalized by endocytosis; localized to sites of polarized growth Verified chr10:50629-53151 50629-53151 99.3% 65.87 74.65 65.47 71.46 67.86 56.69 70.26 68.46 62.28 0.26 0.28 0.26 -0.14 0.47 Covered/w/another[3007]
YJL203W PRP21 "Subunit of the SF3a splicing factor complex, required for spliceosome assembly" Verified chr10:53341-54183 53341-54183 98.4% 81.98 101.27 88.01 85.60 96.45 63.90 91.63 86.80 80.17 0.34 0.35 0.33 -0.11 -0.07 Covered/w/another[3008]
YJL202C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps 3' end of essential PRP21 gene encoding a subunit of the SF3a splicing factor complex" Dubious chr10:53943-54290 53943-54290 98.4% 93.46 128.51 93.46 81.78 105.15 52.57 110.99 87.62 78.86 0.41 0.36 0.33 -0.15 -0.05 Covered/w/another[3008]
YJL201W ECM25 Non-essential protein of unknown function; promoter contains a consensus binding sequence for factor Abf1p Verified chr10:54379-56178 54379-56178 99.1% 118.32 118.32 127.86 95.89 107.11 64.49 118.32 111.87 85.80 0.44 0.45 0.36 -0.38 0.41 Covered/w/another[3008]
YJL200C ACO2 "Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol" Verified chr10:56444-58813 56444-58813 99.0% 179.00 171.33 141.92 112.09 14.92 8.10 175.16 127.00 11.51 0.65 0.52 0.05 -3.46 -2.40 Matched[3009]
YJL199C MBB1 "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; protein detected in large-scale protein-protein interaction studies" Dubious chr10:59855-60181 59855-60181 99.0% 61.80 139.05 58.71 71.07 342.99 185.40 100.42 64.89 264.19 0.37 0.26 1.09 2.03 0.80 Matched[3010]
YJL198W PHO90 "Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth" Verified chr10:60843-63488 60843-63488 98.4% 145.53 137.47 115.96 77.18 13.06 5.76 141.50 96.57 9.41 0.52 0.39 0.04 -3.36 -3.13 Matched[3012]
YJL197W UBP12 "Ubiquitin carboxyl-terminal hydrolase, ubiquitin-specific protease present in the nucleus and cytoplasm that cleaves ubiquitin from ubiquitinated proteins" Verified chr10:63804-67568 63804-67568 98.7% 119.71 103.30 90.12 90.12 52.46 74.25 111.50 90.12 63.35 0.41 0.37 0.26 -0.51 0.03 Matched[3013]
YJL197C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene YJL197C/UBP12" Dubious chr10:65804-66085 65804-66085 98.8% 96.88 93.29 89.70 71.76 46.64 57.41 95.08 80.73 52.03 0.35 0.33 0.22 -0.63 NaN Covered/w/another[3013]
YJL196C ELO1 "Elongase I, medium-chain acyl elongase, catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids" Verified chr10:67849-68781 67849-68781 98.9% 1061.34 2033.79 1007.14 1054.84 958.35 756.71 1547.57 1030.99 857.53 5.71 4.18 3.55 -0.27 -0.14 Matched[3014]
YJL194W CDC6 "Essential ATP-binding protein required for DNA replication, component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association; homologous to S. pombe Cdc18p" Verified chr10:69337-70878 69337-70878 98.8% 74.80 94.48 59.05 62.99 43.96 39.37 84.64 61.02 41.66 0.31 0.25 0.17 -0.55 0.13 Covered/w/another[3015]
YJL195C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YJL194W/CDC6" Dubious chr10:69240-69941 69240-69941 98.7% 67.80 59.15 53.38 50.49 27.41 24.52 63.47 51.93 25.97 0.23 0.21 0.11 -1.00 -0.20 Covered/w/another[3015]
YJL193W "Putative protein of unknown function, predicted to encode a triose phosphate transporter subfamily member based on phylogenetic analysis; similar to YOR307C/SLY41; deletion mutant has a respiratory growth defect" Uncharacterized chr10:71365-72573 71365-72573 99.2% 109.24 133.43 114.25 85.89 88.39 53.37 121.33 100.07 70.88 0.45 0.41 0.29 -0.50 -1.06 Covered/w/another[3015]
YJL192C SOP4 "ER-membrane protein; suppressor of pma1-7, deletion of SOP4 slows down the export of wild-type Pma1p and Pma1-7 from the ER" Verified chr10:72709-73413 72709-73413 99.1% 683.05 746.06 708.83 738.90 661.58 505.49 714.56 723.87 583.53 2.64 2.94 2.42 -0.31 -0.37 Matched[3016]
YJL191W RPS14B "Ribosomal protein 59 of the small subunit, required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; nearly identical to Rps14Ap and similar to E. coli S11 and rat S14 ribosomal proteins" Verified chr10:73786-74610 73786-73795,74204-74610 62.6% 1129.55 582.00 819.40 382.90 390.56 153.16 855.78 601.15 271.86 3.16 2.44 1.13 -1.14 -1.11 Matched[3017]
YJL190C RPS22A Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Bp and has similarity to E. coli S8 and rat S15a ribosomal proteins Verified chr10:74909-75301 74909-75301 85.4% 11684.29 9447.51 10731.20 9280.71 1775.13 1408.79 10565.90 10005.96 1591.96 39.00 40.62 6.60 -2.65 -3.98 Matched[3018]
YJL189W RPL39 "Protein component of the large (60S) ribosomal subunit, has similarity to rat L39 ribosomal protein; required for ribosome biogenesis; exhibits genetic interactions with SIS1 and PAB1" Verified chr10:75932-76473 75932-75937,76324-76473 98.4% 13945.15 10726.04 11560.14 9865.87 4750.48 3538.42 12335.60 10713.01 4144.45 45.54 43.49 17.17 -1.37 -2.76 Matched[3019]
YJL188C BUD19 "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 88% of ORF overlaps the verified gene RPL39; diploid mutant displays a weak budding pattern phenotype in a systematic assay" Dubious chr10:76201-76509 76201-76509 99.0% 8637.26 6761.44 7313.73 6062.09 2921.57 2215.69 7699.35 6687.91 2568.63 28.42 27.15 10.64 -1.38 -0.86 Matched[3019]
YJL187C SWE1 Protein kinase that regulates the G2/M transition by inhibition of Cdc28p kinase activity; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate Verified chr10:76802-79261 76802-79261 99.0% 121.90 122.31 119.44 98.51 43.51 42.28 122.11 108.98 42.89 0.45 0.44 0.18 -1.35 -0.53 Covered[3020]
YJL186W MNN5 "Alpha-1,2-mannosyltransferase, responsible for addition of the second alpha-1,2-linked mannose of the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment" Verified chr10:80153-81913 80153-81913 98.8% 373.02 299.45 358.66 331.64 192.55 159.79 336.24 345.15 176.17 1.24 1.40 0.73 -0.97 -0.49 Matched[3021]
YJL185C "Putative protein of unknown function; mRNA is weakly cell cycle regulated, peaking in G2 phase; YJL185C is a non-essential gene" Uncharacterized chr10:82093-82974 82093-82974 98.8% 69.97 76.85 61.94 60.79 205.32 136.50 73.41 61.37 170.91 0.27 0.25 0.71 1.48 1.10 Matched[3022]
YJL184W GON7 "Protein proposed to be involved in the modification of N-linked oligosaccharides, osmotic stress response, telomere uncapping and elongation, transcription; component of the EKC/KEOPS protein complex with Kae1p, Cgi121p, Pcc1p, and Bud32p" Verified chr10:83446-83817 83446-83817 97.7% 278.01 267.00 300.03 192.68 275.26 209.20 272.51 246.36 242.23 1.01 1.00 1.00 -0.02 -0.18 Covered/w/another[3023]
YJL183W MNN11 "Subunit of a Golgi mannosyltransferase complex that also contains Anp1p, Mnn9p, Mnn10p, and Hoc1p, and mediates elongation of the polysaccharide mannan backbone; has homology to Mnn10p" Verified chr10:84066-85334 84066-85334 98.8% 425.82 363.62 383.56 367.61 263.95 173.04 394.72 375.59 218.49 1.46 1.52 0.91 -0.78 -0.40 Matched[3023]
YJL181W Putative protein of unknown function; expression is cell-cycle regulated as shown by microarray analysis Uncharacterized chr10:85658-87493 85658-87493 99.0% 88.01 92.42 75.36 64.36 79.76 51.16 90.22 69.86 65.46 0.33 0.28 0.27 -0.09 -0.04 Matched[3024]
YJL182C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps uncharacterized ORF YJL181W" Dubious chr10:85433-85750 85433-85750 98.8% 9.55 6.37 25.46 15.91 15.91 31.83 7.96 20.69 23.87 0.03 0.08 0.10 0.21 -0.24 Covered/w/another[3024]
YJL180C ATP12 Conserved protein required for assembly of alpha and beta subunits into the F1 sector of mitochondrial F1F0 ATP synthase; mutation of human ATP12 reduces active ATP synthase levels and is associated with the disorder ATPAF2 deficiency Verified chr10:87581-88558 87581-88558 99.0% 243.67 235.41 241.60 214.76 211.66 133.19 239.54 228.18 172.42 0.88 0.93 0.71 -0.40 -0.25 Matched[3025]
YJL179W PFD1 "Subunit of heterohexameric prefoldin, which binds cytosolic chaperonin and transfers target proteins to it; involved in the biogenesis of actin and of alpha- and gamma-tubulin" Verified chr10:88785-89114 88785-89114 98.7% 411.57 273.36 297.93 254.93 211.93 113.64 342.46 276.43 162.78 1.26 1.12 0.67 -0.76 -0.78 Matched[3026]
YJL178C ATG27 "Type II membrane protein involved in autophagy; binds phosphatidylinositol 3-phosphate, required for the cytoplasm-to-vacuole targeting (Cvt) pathway" Verified chr10:89280-90095 89280-90095 99.1% 471.19 445.22 426.67 396.99 419.25 301.76 458.21 411.83 360.51 1.69 1.67 1.49 -0.19 -0.13 Frag>80[3026,3027,3028]
YJL177W RPL17B "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Ap and has similarity to E. coli L22 and rat L17 ribosomal proteins" Verified chr10:90784-91655 90784-91092,91410-91655 65.4% 4380.43 3738.11 3925.57 3214.33 736.04 534.80 4059.27 3569.95 635.42 14.98 14.49 2.63 -2.49 -2.65 Matched[3029]
YJL175W "Dubious open reading frame unlikely to encode a functional protein; deletion confers resistance to cisplatin, hypersensitivity to 5-fluorouracil, and growth defect at high pH with high calcium; overlaps gene for SWI3 transcription factor" Dubious chr10:94047-94559 94047-94559 99.2% 78.63 74.70 92.39 78.63 60.94 55.04 76.66 85.51 57.99 0.28 0.35 0.24 -0.56 0.37 Covered/w/another[3030]
YJL176C SWI3 "Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2" Verified chr10:92051-94528 92051-94528 99.3% 140.23 129.25 136.57 114.21 110.56 102.43 134.74 125.39 106.49 0.50 0.51 0.44 -0.24 0.04 Matched[3030]
YJL174W KRE9 "Glycoprotein involved in cell wall beta-glucan assembly; null mutation leads to severe growth defects, aberrant multibudded morphology, and mating defects" Verified chr10:95090-95920 95090-95920 98.9% 676.36 687.31 701.91 608.24 1058.34 862.49 681.84 655.08 960.41 2.52 2.66 3.98 0.55 0.99 Matched[3031]
YJL173C RFA3 "Subunit of heterotrimeric Replication Protein A (RPA), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination" Verified chr10:96159-96527 96159-96527 99.2% 480.87 303.28 431.69 346.99 423.50 204.92 392.08 389.34 314.21 1.45 1.58 1.30 -0.31 -0.39 Matched[3032]
YJL172W CPS1 Vacuolar carboxypeptidase yscS; expression is induced under low-nitrogen conditions Verified chr10:97731-99461 97731-99461 99.0% 489.25 603.09 416.27 434.95 425.61 512.60 546.17 425.61 469.11 2.02 1.73 1.94 0.14 0.68 Matched[3033]
YJL171C "GPI-anchored cell wall protein of unknown function; induced in response to cell wall damaging agents and by mutations in genes involved in cell wall biogenesis; sequence similarity to YBR162C/TOS1, a covalently bound cell wall protein" Verified chr10:99698-100888 99698-100888 98.8% 471.69 661.21 448.74 452.14 697.76 679.91 566.45 450.44 688.83 2.09 1.83 2.85 0.61 0.76 Frag>80[3034]
YJL170C ASG7 Protein that regulates signaling from a G protein beta subunit Ste4p and its relocalization within the cell; specific to a-cells and induced by alpha-factor Verified chr10:101144-101773 101144-101773 99.0% 125.12 186.07 205.32 155.59 261.46 141.16 155.59 180.46 201.31 0.57 0.73 0.83 0.16 0.06 Matched[3035]
YJL169W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YJL168C/SET2" Dubious chr10:102093-102461 102093-102461 99.2% 213.07 199.41 193.94 161.17 161.17 98.34 206.24 177.56 129.75 0.76 0.72 0.54 -0.45 -0.01 Covered/w/another[3036]
YJL168C SET2 "Histone methyltransferase with a role in transcriptional elongation, methylates a lysine residue of histone H3; associates with the C-terminal domain of Rpo21p; histone methylation activity is regulated by phosphorylation status of Rpo21p" Verified chr10:102221-104422 102221-104422 99.3% 158.20 168.71 145.39 112.02 109.73 85.04 163.45 128.71 97.39 0.60 0.52 0.40 -0.40 0.02 Matched[3036]
YJL167W ERG20 "Farnesyl pyrophosphate synthetase, has both dimethylallyltranstransferase and geranyltranstransferase activities; catalyzes the formation of C15 farnesyl pyrophosphate units for isoprenoid and sterol biosynthesis" Verified chr10:105008-106066 105008-106066 98.7% 1623.03 1468.00 1557.96 1500.54 1219.19 1090.00 1545.52 1529.25 1154.59 5.71 6.21 4.78 -0.41 -0.07 Frag>80[3037,3038,3039]
YJL166W QCR8 "Subunit 8 of ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; oriented facing the intermembrane space; expression is regulated by Abf1p and Cpf1p" Verified chr10:106428-106712 106428-106712 98.7% 1042.09 1020.75 1379.96 1561.35 4278.60 2816.83 1031.42 1470.66 3547.72 3.81 5.97 14.70 1.27 0.52 Matched[3039]
YJL165C HAL5 "Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters" Verified chr10:106888-109455 106888-109455 99.2% 127.24 116.24 123.70 107.99 237.59 209.31 121.74 115.85 223.45 0.45 0.47 0.93 0.95 1.30 Matched[3040]
YJL164C TPK1 cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk2p and Tpk3p Verified chr10:109960-111153 109960-111153 99.3% 227.66 312.83 365.11 338.12 871.03 620.60 270.25 351.61 745.81 1.00 1.43 3.09 1.08 1.22 Matched[3041]
YJL163C Putative protein of unknown function Uncharacterized chr10:111662-113329 111662-113329 99.0% 59.95 91.45 89.02 69.64 288.27 211.36 75.70 79.33 249.81 0.28 0.32 1.04 1.65 1.85 Matched[3042]
YJL162C JJJ2 "Protein of unknown function, contains a J-domain, which is a region with homology to the E. coli DnaJ protein" Verified chr10:113874-115625 113874-115625 98.7% 73.41 72.83 52.60 41.62 26.01 34.68 73.12 47.11 30.35 0.27 0.19 0.13 -0.63 -0.48 Matched[3043]
YJL161W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr10:117241-117783 117241-117783 98.9% 67.03 147.09 91.23 119.16 1333.13 787.59 107.06 105.20 1060.36 0.40 0.43 4.39 3.33 2.66 Matched[3044]
YJL160C "Putative protein of unknown function; member of the PIR (proteins with internal repeats) family of cell wall proteins; non-essential gene that is required for sporulation; mRNA is weakly cell cycle regulated, peaking in mitosis" Uncharacterized chr10:117958-118821 117958-118821 98.8% 25.78 19.92 16.41 11.72 23.44 7.03 22.85 14.06 15.24 0.08 0.06 0.06 0.12 1.62 Matched[3045]
YJL159W HSP150 "O-mannosylated heat shock protein that is secreted and covalently attached to the cell wall via beta-1,3-glucan and disulfide bridges; required for cell wall stability; induced by heat shock, oxidative stress, and nitrogen limitation" Verified chr10:120445-121686 120445-121686 72.3% 3717.51 3668.48 3884.66 2951.94 7194.32 6760.83 3692.99 3418.30 6977.57 13.63 13.88 28.91 1.03 1.47 Matched[3046]
YJL158C CIS3 Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family Verified chr10:122261-122944 122261-122944 91.9% 2908.90 2519.03 2810.24 2531.76 1134.60 749.50 2713.96 2671.00 942.05 10.02 10.84 3.90 -1.50 -1.63 Matched[3047]
YJL157C FAR1 "Cyclin-dependent kinase inhibitor that mediates cell cycle arrest in response to pheromone; also forms a complex with Cdc24p, Ste4p, and Ste18p that may specify the direction of polarized growth during mating; potential Cdc28p substrate" Verified chr10:123832-126324 123832-126324 99.2% 487.54 540.10 439.03 375.97 84.09 28.70 513.82 407.50 56.39 1.90 1.65 0.23 -2.85 -3.32 Covered/w/another[3048]
YJL156W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr10:126600-126821 126600-126821 98.7% 191.63 209.89 219.01 159.70 269.20 123.19 200.76 189.35 196.20 0.74 0.77 0.81 0.05 -0.06 Covered/w/another[3048]
YJL156C SSY5 "Probable serine protease of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses external amino acid concentration and transmits intracellular signals that regulate expression of amino acid permease genes" Verified chr10:126886-128949 126886-128949 99.1% 110.44 124.12 84.05 97.73 94.31 75.26 117.28 90.89 84.78 0.43 0.37 0.35 -0.10 -0.02 Covered/w/another[3048]
YJL155C FBP26 "Fructose-2,6-bisphosphatase, required for glucose metabolism" Verified chr10:129282-130640 129282-130640 99.3% 85.23 114.88 108.95 98.57 352.78 239.38 100.05 103.76 296.08 0.37 0.42 1.23 1.51 1.26 Matched[3049]
YJL154C VPS35 "Endosomal subunit of membrane-associated retromer complex required for retrograde transport; receptor that recognizes retrieval signals on cargo proteins, forms subcomplex with Vps26p and Vps29p that selects cargo proteins for retrieval" Verified chr10:131098-133932 131098-133932 99.1% 204.03 198.69 203.68 194.77 299.11 254.95 201.36 199.23 277.03 0.74 0.81 1.15 0.48 0.79 Frag>80[3050,3051]
YJL153C INO1 "Inositol 1-phosphate synthase, involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element" Verified chr10:134329-135930 134329-135930 98.9% 22.10 24.63 9.47 12.63 49.25 32.84 23.36 11.05 41.05 0.09 0.04 0.17 1.89 1.38 Matched[3052]
YJL152W "Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr10:136171-136530 136171-136530 98.2% 791.99 961.70 825.93 743.90 1600.94 992.81 876.84 784.91 1296.88 3.24 3.19 5.37 0.72 1.16 Matched[3053]
YJL151C SNA3 "Integral membrane protein localized to vacuolar intralumenal vesicles, computational analysis of large-scale protein-protein interaction data suggests a possible role in either cell wall synthesis or protein-vacuolar targeting" Verified chr10:136369-136770 136369-136770 98.5% 1441.77 1835.67 1426.62 1292.79 2633.56 1823.04 1638.72 1359.71 2228.30 6.05 5.52 9.23 0.71 0.80 Matched[3053]
YJL150W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr10:137120-137422 137120-137422 99.2% 3.33 19.96 6.65 13.30 9.98 13.30 11.64 9.98 11.64 0.04 0.04 0.05 0.22 0.68 Overlap[3054]
YJL149W Putative SCF ubiquitin ligase F-box protein; interacts physically with both Cdc53p and Skp1 and genetically with CDC34; similar to putative F-box protein YDR131C; null mutant suppresses dst1delta sensitivity for 6-azauracil Verified chr10:137376-139367 137376-139367 99.1% 53.70 49.65 58.26 53.70 92.20 85.11 51.67 55.98 88.65 0.19 0.23 0.37 0.66 1.24 Matched[3054]
YJL148W RPA34 RNA polymerase I subunit A34.5 Verified chr10:140434-141135 140434-141135 98.5% 702.69 365.81 388.94 347.01 53.50 7.23 534.25 367.97 30.36 1.97 1.49 0.13 -3.60 -4.07 Matched[3056]
YJL147C Mitochondrial protein of unknown function; homozygous diploid deletion strain has a sporulation defect characterized by elevated dityrosine in the soluble fraction; expression induced by calcium shortage; YJL147W is a non-essential gene Uncharacterized chr10:141416-142564 141416-142564 99.2% 48.25 58.78 50.88 47.37 57.90 38.60 53.51 49.13 48.25 0.20 0.20 0.20 -0.03 -0.39 Matched[3057]
YJL146W IDS2 "Protein involved in modulation of Ime2p activity during meiosis, appears to act indirectly to promote Ime2p-mediated late meiotic functions; found in growing cells and degraded during sporulation" Verified chr10:143289-144698 143289-144698 98.7% 84.81 79.06 79.06 64.69 120.03 87.69 81.94 71.88 103.86 0.30 0.29 0.43 0.53 0.65 Matched[3058]
YJL145W SFH5 "Putative phosphatidylinositol transfer protein (PITP), exhibits phosphatidylinositol- but not phosphatidylcholine-transfer activity, localized to cytosol and microsomes, similar to Sec14p; may be PITP regulator rather than actual PITP" Verified chr10:145157-146041 145157-146041 98.8% 336.22 213.86 330.51 247.02 144.10 112.07 275.04 288.76 128.09 1.02 1.17 0.53 -1.17 -0.95 Frag>80[3059,3060,3061]
YJL144W "Cytoplasmic hydrophilin of unknown function, possibly involved in the dessication response; expression induced by osmotic stress, starvation and during stationary phase; GFP-fusion protein is induced by the DNA-damaging agent MMS" Uncharacterized chr10:146356-146670 146356-146670 98.2% 29.09 48.48 61.41 42.01 1476.97 1063.29 38.78 51.71 1270.13 0.14 0.21 5.26 4.62 4.12 Matched[3061]
YJL143W TIM17 Essential constituent of the mitochondrial inner membrane presequence translocase; interacts with Pam18p to recruit the presequence translocase-associated motor (PAM complex) and also required for protein sorting during import Verified chr10:147098-147574 147098-147574 98.3% 993.52 861.33 935.95 790.97 564.98 345.39 927.42 863.46 455.18 3.42 3.50 1.89 -0.92 -0.64 Matched[3062]
YJL142C Hypothetical protein; null mutant displays increased levels of spontaneous Rad52 foci Dubious chr10:147816-148208 147816-148208 98.7% 213.92 234.54 262.89 213.92 1247.42 925.26 224.23 238.40 1086.34 0.83 0.97 4.50 2.19 1.75 Covered/w/another[3063]
YJL141C YAK1 Serine-threonine protein kinase that is part of a glucose-sensing system involved in growth control in response to glucose availability; translocates from the cytoplasm to the nucleus and phosphorylates Pop2p in response to a glucose signal Verified chr10:147964-150387 147964-150387 98.7% 110.77 139.61 161.77 176.81 560.96 696.81 125.19 169.29 628.88 0.46 0.69 2.61 1.89 2.11 Matched[3063]
YJL140W RPB4 RNA polymerase II subunit B32; forms two subunit dissociable complex with Rpb7p; dispensable under some environmental conditions; involved in export of mRNA to cytoplasm under stress conditions; involved in telomere maintenance Verified chr10:150958-151623 150958-151623 98.3% 640.14 542.36 640.14 491.95 1041.95 637.09 591.25 566.04 839.52 2.18 2.30 3.48 0.57 0.33 Matched[3064]
YJL139C YUR1 "Mannosyltransferase of the KTR1 family, involved in protein N-glycosylation; located in the Golgi apparatus" Verified chr10:151710-152996 151710-152996 99.1% 76.08 66.67 80.00 64.31 90.98 54.12 71.37 72.16 72.55 0.26 0.29 0.30 0.01 0.16 Matched[3065]
YJL138C TIF2 "Translation initiation factor eIF4A, identical to Tif1p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G" Verified chr10:153501-154688 153501-154688 6.7% 4128.90 2806.65 3280.67 3380.46 648.65 461.54 3467.78 3330.56 555.09 12.80 13.52 2.30 -2.58 -2.07 Frag<80[3066,3067,3068,3069]
YJL137C GLG2 "Self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside; similar to mammalian glycogenin" Verified chr10:154982-156124 154982-156124 99.0% 72.45 84.82 83.93 75.10 185.54 136.95 78.63 79.52 161.24 0.29 0.32 0.67 1.02 1.27 Matched[3070]
YJL136W-A Identified by SAGE Uncharacterized chr10:156166-156249 156166-156249 98.9% 24.08 12.04 60.21 0.00 36.13 36.13 18.06 30.11 36.13 0.07 0.12 0.15 0.26 NaN Covered/w/another[3070]
YJL136C RPS21B Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Ap and has similarity to rat S21 ribosomal protein Verified chr10:156547-157270 156547-156786,157247-157270 84.5% 6706.74 5058.05 5609.11 4578.68 3167.44 2132.54 5882.40 5093.90 2649.99 21.71 20.68 10.98 -0.94 -1.52 Frag>80[3071,3072]
YJL135W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified genes YJL134W/LCB3" Dubious chr10:157874-158191 157874-158191 98.8% 38.18 15.91 34.99 41.36 9.54 19.09 27.04 38.18 14.32 0.10 0.15 0.06 -1.42 0.12 Covered/w/another[3073]
YJL134W LCB3 "Long-chain base-1-phosphate phosphatase with specificity for dihydrosphingosine-1-phosphate, regulates ceramide and long-chain base phosphates levels, involved in incorporation of exogenous long chain bases in sphingolipids" Verified chr10:158185-159414 158185-159414 98.7% 260.41 306.56 248.05 201.08 148.34 105.48 283.49 224.56 126.91 1.05 0.91 0.53 -0.82 -0.51 Matched[3073]
YJL133C-A "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr10:159620-159844 159620-159844 98.3% 587.68 827.27 881.52 533.43 2748.54 1464.68 707.48 707.48 2106.61 2.61 2.87 8.73 1.57 NaN Matched[3074]
YJL133W MRS3 "Mitochondrial iron transporter of the mitochondrial carrier family (MCF), very similar to and functionally redundant with Mrs4p; functions under low-iron conditions; may transport other cations in addition to iron" Verified chr10:160616-161560 160616-161560 98.6% 189.87 167.34 163.05 119.07 131.94 95.47 178.61 141.06 113.71 0.66 0.57 0.47 -0.31 -0.14 Matched[3076]
YJL132W Putative protein of unknown function; localizes to the membrane fraction; possible Zap1p-regulated target gene induced by zinc deficiency; YJL132W is a non-essential gene Uncharacterized chr10:161911-164163 161911-164163 98.8% 31.43 48.49 37.27 29.19 92.05 54.78 39.96 33.23 73.41 0.15 0.13 0.30 1.14 0.72 Matched[3077]
YJL131C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YJL131C is not an essential gene" Uncharacterized chr10:164275-165345 164275-165345 99.4% 140.87 154.95 144.62 138.05 316.48 176.55 147.91 141.34 246.52 0.55 0.57 1.02 0.80 0.59 Matched[3078]
YJL130C URA2 "Bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), catalyzes the first two enzymatic steps in the de novo biosynthesis of pyrimidines; both activities are subject to feedback inhibition by UTP" Verified chr10:165720-172750 165720-172429,172749-172750 98.9% 801.99 630.87 785.72 1010.17 164.80 405.67 716.43 897.95 285.23 2.64 3.64 1.18 -1.65 -0.76 Frag<80[3079,3080]
YJL129C TRK1 "Component of the Trk1p-Trk2p potassium transport system; 180 kDa high affinity potassium transporter; phosphorylated in vivo and interacts physically with the phosphatase Ppz1p, suggesting Trk1p acitivy is regulated by phosphorylation" Verified chr10:173596-177303 173596-177303 99.2% 179.47 172.67 139.77 122.37 76.41 61.73 176.07 131.07 69.07 0.65 0.53 0.29 -0.92 -0.49 Covered[3081]
YJL128C PBS2 "MAP kinase kinase that plays a pivotal role in the osmosensing signal-transduction pathway, activated under severe osmotic stress" Verified chr10:178094-180100 178094-180100 99.0% 169.11 172.13 167.10 167.10 218.43 177.67 170.62 167.10 198.05 0.63 0.68 0.82 0.25 0.68 Matched[3082]
YJL127W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr10:180191-180307 180191-180307 98.9% 60.50 77.78 77.78 60.50 86.42 112.35 69.14 69.14 99.39 0.26 0.28 0.41 0.52 -0.12 Covered/w/another[3082]
YJL127C-B "Putative protein of unknown function; identified based on homology to the filamentous fungus, Ashbya gossypii" Uncharacterized chr10:181549-181707 181549-181707 99.0% 457.38 470.09 438.33 393.86 851.24 457.38 463.74 416.09 654.31 1.71 1.69 2.71 0.65 NaN Matched[3083]
YJL127C SPT10 "Putative histone acetylase, sequence-specific activator of histone genes, binds specifically and highly cooperatively to pairs of UAS elements in core histone promoters, functions at or near the TATA box" Verified chr10:182296-184218 182296-184218 99.2% 59.23 63.95 46.65 38.26 39.31 34.60 61.59 42.46 36.95 0.23 0.17 0.15 -0.20 0.70 Matched[3084]
YJL126W NIT2 "Nit protein, one of two proteins in S. cerevisiae with similarity to the Nit domain of NitFhit from fly and worm and to the mouse and human Nit protein which interacts with the Fhit tumor suppressor; nitrilase superfamily member" Verified chr10:184499-185422 184499-185422 98.6% 86.67 89.96 78.99 64.73 110.81 74.60 88.32 71.86 92.70 0.33 0.29 0.38 0.37 0.14 Matched[3085]
YJL125C GCD14 "Subunit of tRNA (1-methyladenosine) methyltransferase, with Gcd10p, required for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression" Verified chr10:185526-186677 185526-186677 99.2% 161.92 109.41 88.40 97.15 27.13 25.38 135.66 92.78 26.26 0.50 0.38 0.11 -1.82 -0.55 Matched[3086]
YJL124C LSM1 "Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) involved in degradation of cytoplasmic mRNAs" Verified chr10:187125-187643 187125-187643 99.2% 774.95 757.47 786.60 767.18 598.20 429.23 766.21 776.89 513.72 2.83 3.15 2.13 -0.60 -0.44 Matched[3088]
YJL123C Protein of unknown function that may interact with ribosomes; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to COPI-coated vesicles (early Golgi); YJL123C is a non-essential gene Verified chr10:188003-189439 188003-189439 98.3% 477.66 470.59 486.86 450.07 634.76 454.31 474.13 468.47 544.54 1.75 1.90 2.26 0.22 0.31 Matched[3089]
YJL122W ALB1 Shuttling pre-60S factor; involved in the biogenesis of ribosomal large subunit; interacts directly with Arx1p; responsible for Tif6p recycling defects in absence of Rei1p Verified chr10:189715-190242 189715-190242 98.4% 442.80 261.83 271.46 202.15 34.65 0.00 352.32 236.80 17.33 1.30 0.96 0.07 -3.77 -3.33 Matched[3090]
YJL120W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YJL121C/RPE1; deletion confers sensitivity to GSAO" Dubious chr10:191021-191344 191021-191344 99.1% 112.12 146.38 168.18 124.58 80.98 109.01 129.25 146.38 94.99 0.48 0.59 0.39 -0.62 -0.06 Covered/w/another[3092]
YJL121C RPE1 "D-ribulose-5-phosphate 3-epimerase, catalyzes a reaction in the non-oxidative part of the pentose-phosphate pathway; mutants are sensitive to oxidative stress" Verified chr10:190373-191089 190373-191089 98.6% 653.81 626.92 611.36 590.13 403.33 397.66 640.37 600.74 400.50 2.36 2.44 1.66 -0.58 -0.20 Matched[3091]
YJL118W "Putative protein of unknown function; may interact with ribosomes, based on co-purification experiments; YJL18W is a non-essential gene; deletion enhances the toxicity of heterologously expressed human alpha-synuclein" Verified chr10:191638-192297 191638-192297 98.8% 96.63 99.69 88.96 59.82 56.75 33.74 98.16 74.39 45.25 0.36 0.30 0.19 -0.72 -0.88 Matched[3092]
YJL119C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr10:191571-191894 191571-191894 99.0% 71.67 71.67 68.55 28.04 49.86 37.39 71.67 48.30 43.63 0.26 0.20 0.18 -0.15 -0.28 Matched[3092]
YJL117W PHO86 "Endoplasmic reticulum (ER) resident protein required for ER exit of the high-affinity phosphate transporter Pho84p, specifically required for packaging of Pho84p into COPII vesicles" Verified chr10:192530-193465 192530-193465 98.9% 720.66 656.91 800.61 625.58 560.75 464.59 688.79 713.10 512.67 2.54 2.89 2.12 -0.48 -0.20 Matched[3093]
YJL116C NCA3 Protein that functions with Nca2p to regulate mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p ) of the Fo-F1 ATP synthase; member of the SUN family Verified chr10:193859-194872 193859-194872 98.4% 46.09 87.17 28.05 40.08 76.15 54.10 66.63 34.07 65.12 0.25 0.14 0.27 0.93 0.12 Covered[3094]
YJL115W ASF1 "Nucleosome assembly factor, involved in chromatin assembly and disassembly, anti-silencing protein that causes derepression of silent loci when overexpressed" Verified chr10:196285-197124 196285-197124 97.9% 364.83 297.95 368.48 237.14 171.47 201.87 331.39 302.81 186.67 1.22 1.23 0.77 -0.70 -0.40 Frag>80[3095,3096]
YJL112W MDV1 "Peripheral protein of the cytosolic face of the mitochondrial outer membrane, required for mitochondrial fission; interacts with Fis1p and with the dynamin-related GTPase Dnm1p; contains WD repeats" Verified chr10:205301-207445 205301-207445 98.6% 141.89 133.37 122.97 107.36 110.20 71.42 137.63 115.16 90.81 0.51 0.47 0.38 -0.34 -0.85 Matched[3097]
YJL111W CCT7 "Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo" Verified chr10:207873-209525 207873-209525 98.6% 687.50 521.30 639.66 588.15 296.83 268.62 604.40 613.91 282.73 2.23 2.49 1.17 -1.12 -0.66 Matched[3098]
YJL110C GZF3 GATA zinc finger protein and Dal80p homolog that negatively regulates nitrogen catabolic gene expression by competing with Gat1p for GATA site binding; function requires a repressive carbon source; dimerizes with Dal80p and binds to Tor1p Verified chr10:209918-211573 209918-211573 99.0% 121.40 144.58 126.89 113.47 86.01 77.47 132.99 120.18 81.74 0.49 0.49 0.34 -0.56 -0.21 Matched[3099]
YJL109C UTP10 "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" Verified chr10:211996-217305 211996-217305 99.1% 175.77 103.94 101.09 80.19 13.87 7.98 139.86 90.64 10.93 0.52 0.37 0.05 -3.05 -3.05 Matched[3100]
YJL108C PRM10 "Pheromone-regulated protein, predicted to have 5 transmembrane segments" Verified chr10:217701-218852 217701-218852 98.7% 29.91 17.60 24.63 13.20 67.74 49.27 23.75 18.91 58.50 0.09 0.08 0.24 1.63 2.12 Covered/w/another[3101]
YJL107C "Putative protein of unknown function; expression is induced by activation of the HOG1 mitogen-activated signaling pathway and this induction is Hog1p/Pbs2p dependent; YJL107C and adjacent ORF, YJL108C are merged in related fungi" Uncharacterized chr10:218849-220012 218849-220012 99.0% 14.75 8.67 4.34 12.14 25.16 37.30 11.71 8.24 31.23 0.04 0.03 0.13 1.92 2.26 Covered/w/another[3101]
YJL106W IME2 "Serine/threonine protein kinase involved in activation of meiosis, associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p" Verified chr10:221386-223323 221386-223323 98.9% 17.21 25.03 12.52 14.08 54.76 21.90 21.12 13.30 38.33 0.08 0.05 0.16 1.53 1.40 Covered/w/another[3101]
YJL105W SET4 "Protein of unknown function, contains a SET domain" Verified chr10:225051-226733 225051-226733 98.7% 28.28 33.70 29.48 19.86 30.69 16.85 30.99 24.67 23.77 0.11 0.10 0.10 -0.05 0.27
YJL104W PAM16 "Constituent of the mitochondrial import motor associated with the presequence translocase, along with Ssc1p, Tim44p, Mge1p, and Pam18p; forms a 1:1 subcomplex with Pam18p and inhibits its cochaperone activity; contains J-like domain" Verified chr10:227323-227772 227323-227772 98.2% 542.99 552.04 583.71 468.33 520.36 325.79 547.51 526.02 423.08 2.02 2.14 1.75 -0.31 -0.38 Matched[3102]
YJL103C "Putative zinc cluster protein of unknown function; proposed to be involved in the regulation of energy metabolism, based on patterns of expression and sequence analysis" Uncharacterized chr10:229021-230877 229021-230877 99.1% 32.07 48.38 47.83 70.12 99.47 97.30 40.22 58.98 98.39 0.15 0.24 0.41 0.74 1.10 Matched[3105]
YJL102W MEF2 Mitochondrial elongation factor involved in translational elongation Verified chr10:231297-233756 231297-233756 98.9% 49.75 54.28 51.40 76.89 131.58 84.29 52.01 64.14 107.93 0.19 0.26 0.45 0.75 0.88 Matched[3106]
YJL101C GSH1 "Gamma glutamylcysteine synthetase catalyzes the first step in glutathione (GSH) biosynthesis; expression induced by oxidants, cadmium, and mercury" Verified chr10:234316-236352 234316-236352 99.1% 294.87 207.15 355.83 229.45 177.91 153.63 251.01 292.64 165.77 0.93 1.19 0.69 -0.82 -0.20 Matched[3108]
YJL100W LSB6 "Phosphatidylinositol 4-kinase that binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization" Verified chr10:237259-239082 237259-239082 98.5% 76.27 57.90 69.59 52.33 143.64 116.92 67.09 60.96 130.28 0.25 0.25 0.54 1.10 1.39 Matched[3109]
YJL099W CHS6 "Member of the Chs5p-Arf1p-binding proteins (ChAPs), a group of 4 related, interacting proteins (Bch1p, Fmp50p, Bud7p, Chs6p) that mediate export of specific cargo proteins, including chitin synthase Chs3p, from the Golgi to plasma membrane" Verified chr10:239410-241650 239410-241650 98.8% 52.83 65.47 47.86 44.70 85.34 55.08 59.15 46.28 70.21 0.22 0.19 0.29 0.60 0.55 Covered[3110]
YJL098W SAP185 "Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap155p, and Sap190p" Verified chr10:242078-245254 242078-245254 98.5% 95.89 49.54 51.14 28.77 12.47 11.19 72.72 39.96 11.83 0.27 0.16 0.05 -1.76 -0.99 Frag>80[3111]
YJL097W PHS1 "Protein of unknown function; homolog of mammalian PTPLA; involved in sphingolipid biosynthesis, protein trafficking; required for cell viability" Verified chr10:245587-246240 245587-246240 99.2% 579.65 670.61 480.99 470.20 488.69 342.24 625.13 475.59 415.47 2.31 1.93 1.72 -0.19 -0.03 Matched[3112]
YJL096W MRPL49 Mitochondrial ribosomal protein of the large subunit Verified chr10:246486-246971 246486-246971 98.9% 339.11 328.71 368.24 357.84 534.67 351.60 333.91 363.04 443.13 1.23 1.47 1.84 0.29 0.07 Matched[3113]
YJL095W BCK1 "Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinase C signaling pathway, which controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p" Verified chr10:247250-251686 247250-251686 98.9% 66.77 67.23 62.90 66.09 32.59 36.69 67.00 64.50 34.64 0.25 0.26 0.14 -0.90 0.04 Matched[3114]
YJL094C KHA1 "Putative K+/H+ antiporter with a probable role in intracellular cation homeostasis, localized to Golgi vesicles and detected in highly purified mitochondria in high-throughput studies" Verified chr10:251816-254437 251816-254437 98.9% 71.72 72.10 61.31 57.84 112.97 91.00 71.91 59.57 101.99 0.27 0.24 0.42 0.78 1.23 Matched[3115]
YJL093C TOK1 "Outward-rectifier potassium channel of the plasma membrane with two pore domains in tandem, each of which forms a functional channel permeable to potassium; carboxy tail functions to prevent inner gate closures; target of K1 toxin" Verified chr10:254732-256807 254732-256807 99.0% 108.04 110.96 106.58 94.42 113.88 78.84 109.50 100.50 96.36 0.40 0.41 0.40 -0.06 0.53 Matched[3116]
YJL092W SRS2 "DNA helicase and DNA-dependent ATPase involved in DNA repair, needed for proper timing of commitment to meiotic recombination and transition from Meiosis I to II; affects genome stability by suppressing unscheduled homologous recombination" Verified chr10:257418-260942 257418-260942 98.7% 140.77 122.10 104.29 83.03 62.63 70.39 131.43 93.66 66.51 0.49 0.38 0.28 -0.49 0.03 Matched[3117]
YJL091C GWT1 "Protein involved in the inositol acylation of glucosaminyl phosphatidylinositol (GlcN-PI) to form glucosaminyl(acyl)phosphatidylinositol (GlcN(acyl)PI), an intermediate in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors" Verified chr10:261075-262547 261075-262547 99.0% 151.52 129.58 126.84 128.21 301.66 177.57 140.55 127.52 239.62 0.52 0.52 0.99 0.91 0.77 Matched[3118]
YJL090C DPB11 "Subunit of DNA Polymerase II Epsilon complex; has BRCT domain, required on the prereplicative complex at replication origins for loading DNA polymerases to initiate DNA synthesis, also required for S/M checkpoint control" Verified chr10:262752-265046 262752-265046 99.1% 69.47 68.59 72.55 51.89 50.57 37.81 69.03 62.22 44.19 0.25 0.25 0.18 -0.49 0.23 Matched[3119]
YJL089W SIP4 C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus Verified chr10:265921-268410 265921-268410 99.3% 2.83 10.92 4.04 2.43 75.24 60.67 6.88 3.24 67.95 0.03 0.01 0.28 4.39 3.93 Frag>80[3120,3121]
YJL088W ARG3 "Ornithine carbamoyltransferase (carbamoylphosphate:L-ornithine carbamoyltransferase), catalyzes the sixth step in the biosynthesis of the arginine precursor ornithine" Verified chr10:268794-269810 268794-269810 99.1% 19.85 59.55 3.97 7.94 19.85 15.88 39.70 5.95 17.86 0.15 0.02 0.07 1.58 0.58 Overlap[3122]
YJL087C TRL1 "tRNA ligase, required for tRNA splicing; composed of three essential domains containing the phosphodiesterase, polynucleotide kinase, and ligase activities required for ligation; localized at the inner membrane of the nuclear envelope" Verified chr10:269997-272480 269997-272480 99.5% 74.48 64.36 53.83 48.57 34.00 24.69 69.42 51.20 29.35 0.26 0.21 0.12 -0.80 -0.43 Covered[3122]
YJL085W EXO70 "Essential 70kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis" Verified chr10:272822-274693 272822-274693 98.8% 103.24 117.29 101.07 85.94 121.07 62.70 110.26 93.51 91.89 0.41 0.38 0.38 -0.03 0.13 Matched[3123]
YJL086C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified genes YJL085W/EXO70 and YJL087C/TRL1" Dubious chr10:272473-272841 272473-272841 98.7% 27.45 21.96 13.73 10.98 10.98 13.73 24.71 12.35 12.35 0.09 0.05 0.05 0.00 0.01 Overlap[3122,3123]
YJL084C ALY2 "Cytoplasmic protein of unknown function that interacts with the cyclin Pcl7p; phosphorylated in vitro by the cyclin-CDK complex, Pcl7p-Pho85p; identified as a potential Cdc28p substrate; mRNA is cell cycle regulated, peaking in M phase" Verified chr10:274857-277997 274857-277997 98.8% 90.19 99.85 76.98 76.98 82.46 105.32 95.02 76.98 93.89 0.35 0.31 0.39 0.29 1.05 Frag>80[3124]
YJL083W TAX4 "Protein involved in regulation of phosphatidylinositol 4,5-bisphosphate concentrations; Irs4p and Tax4p bind and activate the phosphatase Inp51p" Verified chr10:278836-280650 278836-280650 98.6% 44.15 40.80 43.03 32.97 78.24 91.66 42.47 38.00 84.95 0.16 0.15 0.35 1.16 1.65 Matched[3125]
YJL082W IML2 "Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr10:281180-283375 281180-283375 98.7% 113.47 125.46 129.15 126.84 311.34 342.71 119.46 128.00 327.02 0.44 0.52 1.35 1.35 1.85 Matched[3126]
YJL081C ARP4 "Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes" Verified chr10:283797-285266 283797-285266 99.1% 305.56 293.20 257.50 289.08 189.52 170.98 299.38 273.29 180.25 1.11 1.11 0.75 -0.60 -0.29 Matched[3128]
YJL080C SCP160 "Essential RNA-binding G protein effector of mating response pathway, mainly associated with nuclear envelope and ER, interacts in mRNA-dependent manner with translating ribosomes via multiple KH domains, similar to vertebrate vigilins" Verified chr10:285553-289221 285553-289221 99.0% 599.68 528.37 554.53 553.43 118.39 128.03 564.03 553.98 123.21 2.08 2.25 0.51 -2.17 -1.33 Frag>80[3129,3130]
YJL079C PRY1 "Protein of unknown function, has similarity to Pry2p and Pry3p and to the plant PR-1 class of pathogen related proteins" Verified chr10:289870-290769 289870-290769 98.0% 1916.78 3343.88 1993.86 1964.39 559.96 451.14 2630.33 1979.12 505.55 9.71 8.03 2.09 -1.97 -1.47 Matched[3131]
YJL078C PRY3 "Protein of unknown function, has similarity to Pry1p and Pry2p and to the plant PR-1 class of pathogen related proteins" Verified chr10:291331-293976 291331-293976 98.1% 291.35 365.34 305.61 220.82 163.02 188.45 328.34 263.22 175.73 1.21 1.07 0.73 -0.58 0.35 Covered/w/another[3132]
YJL077W-B "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr10:294042-294140 294042-294140 98.8% 143.16 194.29 163.61 122.71 143.16 71.58 168.73 143.16 107.37 0.62 0.58 0.44 -0.42 NaN Covered/w/another[3132]
YJL077W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene YJL077C/ICS3" Dubious chr10:294794-294880 294794-294880 99.1% 231.88 278.26 197.10 185.51 185.51 92.75 255.07 191.30 139.13 0.94 0.78 0.58 -0.46 NaN Covered/w/another[3132]
YJL077C ICS3 Protein of unknown function Verified chr10:294661-295056 294661-295056 98.9% 217.11 168.58 181.35 137.93 196.68 99.62 192.85 159.64 148.15 0.71 0.65 0.61 -0.11 -0.52 Covered/w/another[3132]
YJL076W NET1 "Core subunit of the RENT complex, which is a complex involved in nucleolar silencing and telophase exit; stimulates transcription by RNA polymerase I and regulates nucleolar structure" Verified chr10:295240-298809 295240-298809 98.6% 370.17 323.58 314.77 287.22 121.88 219.32 346.88 300.99 170.60 1.28 1.22 0.71 -0.82 -0.16 Covered/w/another[3132]
YJL075C APQ13 "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 85% of ORF overlaps the verified gene NET1; null mutant is sensitive to sorbate" Dubious chr10:298455-298871 298455-298871 98.9% 635.54 487.57 514.25 417.22 293.51 351.73 561.55 465.74 322.62 2.07 1.89 1.34 -0.53 -0.21 Covered/w/another[3132]
YJL074C SMC3 "Subunit of the multiprotein cohesin complex required for sister chromatid cohesion in mitotic cells; also required, with Rec8p, for cohesion and recombination during meiosis; phylogenetically conserved SMC chromosomal ATPase family member" Verified chr10:299152-302844 299152-302844 99.4% 123.34 73.52 94.48 83.32 35.94 20.42 98.43 88.90 28.18 0.36 0.36 0.12 -1.66 -1.49 Matched[3133]
YJL073W JEM1 "DnaJ-like chaperone required for nuclear membrane fusion during mating, localizes to the ER membrane; exhibits genetic interactions with KAR2" Verified chr10:303176-305113 303176-305113 98.9% 123.65 122.61 118.43 102.78 101.22 90.26 123.13 110.61 95.74 0.45 0.45 0.40 -0.21 0.34 Matched[3134]
YJL072C PSF2 "Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery" Verified chr10:305216-305857 305216-305857 99.1% 86.46 106.89 105.32 119.47 116.32 66.02 96.67 112.39 91.17 0.36 0.46 0.38 -0.30 -0.61 Covered/w/another[3134]
YJL071W ARG2 "Acetylglutamate synthase (glutamate N-acetyltransferase), mitochondrial enzyme that catalyzes the first step in the biosynthesis of the arginine precursor ornithine; forms a complex with Arg5,6p" Verified chr10:306127-307851 306127-307851 98.9% 42.78 98.45 51.57 35.16 42.78 53.33 70.61 43.36 48.05 0.26 0.18 0.20 0.15 0.33 Matched[3135]
YJL070C "Putative protein of unknown function with similarity to AMP deaminases; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YJL070C is a non-essential gene" Uncharacterized chr10:307966-310632 307966-310632 99.1% 51.81 60.51 83.58 81.69 132.37 114.59 56.16 82.64 123.48 0.21 0.34 0.51 0.58 1.00 Matched[3136]
YJL069C UTP18 "Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data" Verified chr10:310917-312701 310917-312701 99.0% 159.56 110.90 109.77 80.91 14.71 6.22 135.23 95.34 10.47 0.50 0.39 0.04 -3.19 -3.44 Matched[3137]
YJL068C "Non-essential intracellular esterase that can function as an S-formylglutathione hydrolase; may be involved in the detoxification of formaldehyde, which can be metabolized to S-formylglutathione; similar to human esterase D" Verified chr10:313011-313910 313011-313910 98.7% 284.70 401.73 354.46 337.58 638.03 541.26 343.21 346.02 589.65 1.27 1.40 2.44 0.77 1.23 Covered/w/another[3138]
YJL067W "Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr10:314079-314429 314079-314429 99.0% 201.46 299.32 276.29 236.00 952.63 754.05 250.39 256.15 853.34 0.92 1.04 3.54 1.74 0.99 Covered/w/another[3138]
YJL066C MPM1 "Mitochondrial membrane protein of unknown function, contains no hydrophobic stretches" Verified chr10:314109-314867 314109-314867 98.7% 176.27 257.73 235.03 188.29 843.98 624.97 217.00 211.66 734.48 0.80 0.86 3.04 1.79 2.04 Covered/w/another[3138]
YJL064W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene YJL065C/DLS1" Dubious chr10:315170-315565 315170-315565 98.6% 230.47 276.57 169.01 171.57 163.89 102.43 253.52 170.29 133.16 0.94 0.69 0.55 -0.35 0.10 Covered/w/another[3138]
YJL065C DLS1 "Subunit of ISW2/yCHRAC chromatin accessibility complex along with Itc1p, Isw2p, and Dpb4p; involved in inheritance of telomeric silencing" Verified chr10:315049-315552 315049-315552 98.6% 241.43 267.58 179.06 169.00 175.04 94.56 254.51 174.03 134.80 0.94 0.71 0.56 -0.37 0.02 Covered/w/another[3138]
YJL063C MRPL8 Mitochondrial ribosomal protein of the large subunit Verified chr10:315754-316470 315754-316470 99.0% 370.60 325.50 367.78 329.73 367.78 284.64 348.05 348.76 326.21 1.28 1.42 1.35 -0.10 -0.00 Covered/w/another[3138]
YJL062W-A "Putative protein of unknown function, identified based on comparison to related yeast species; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr10:316718-316975 316718-316975 98.1% 640.11 592.69 730.98 659.86 1157.72 802.11 616.40 695.42 979.91 2.28 2.82 4.06 0.49 0.27 Matched[3139]
YJL062W LAS21 Integral plasma membrane protein involved in the synthesis of the glycosylphosphatidylinositol (GPI) core structure; mutations affect cell wall integrity Verified chr10:317279-319771 317279-319771 99.0% 150.30 170.96 151.92 158.40 74.14 80.62 160.63 155.16 77.38 0.59 0.63 0.32 -1.00 -0.18 Matched[3140]
YJL061W NUP82 "Nucleoporin, subunit of the nuclear pore complex (NPC); forms a subcomplex with Nup159p and Nsp1p, interacts with Nup116p and is required for proper localization of Nup116p in the NPC" Verified chr10:320011-322152 320011-322152 99.0% 171.22 140.09 137.26 147.64 139.15 108.02 155.66 142.45 123.58 0.57 0.58 0.51 -0.20 -0.09 Matched[3141]
YJL060W BNA3 "Arylformamidase, involved in biosynthesis of nicotinic acid from tryptophan via kynurenine pathway; potential Cdc28p substrate" Verified chr10:323381-324715 323381-324715 98.9% 251.44 385.50 315.82 274.92 368.83 304.46 318.47 295.37 336.65 1.18 1.20 1.39 0.19 0.66 Matched[3143]
YJL059W YHC3 Vacuolar membrane protein involved in the ATP-dependent transport of arginine into the vacuole and possibly in balancing ion homeostasis; homolog of human CLN3 involved in Batten disease (juvenile onset neuronal ceroid lipofuscinosis) Verified chr10:324959-326185 324959-326185 99.0% 88.04 117.66 74.88 67.47 98.74 78.99 102.85 71.17 88.86 0.38 0.29 0.37 0.32 0.90 Covered/w/another[3144]
YJL058C BIT61 "Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p-Slm1p-Slm2p), a membrane-associated complex that regulates cell cycle-dependent actin cytoskeletal dynamics during polarized growth and cell wall integrity" Verified chr10:326237-327868 326237-327868 99.1% 35.25 33.40 30.92 27.21 25.97 16.08 34.32 29.07 21.03 0.13 0.12 0.09 -0.47 -0.43 Covered/w/another[3144]
YJL057C IKS1 Putative serine/threonine kinase; expression is induced during mild heat stress; deletion mutants are hypersensitive to copper sulphate and resistant to sorbate; interacts with an N-terminal fragment of Sst2p Verified chr10:328113-330116 328113-330116 99.2% 62.39 92.58 78.49 92.08 468.93 362.26 77.48 85.28 415.60 0.29 0.35 1.72 2.28 2.49 Matched[3145]
YJL056C ZAP1 "Zinc-regulated transcription factor, binds to zinc-responsive promoter elements to induce transcription of certain genes in the presence of zinc; regulates its own transcription; contains seven zinc-finger domains" Verified chr10:330426-333068 330426-333068 98.9% 59.67 71.52 45.90 45.13 35.19 29.83 65.59 45.51 32.51 0.24 0.18 0.13 -0.49 -0.06 Matched[3146]
YJL055W "Putative protein of unknown function; deletion mutants are sensitive to purine base analogs, 6-hydroxylaminopurine (HAP) and 2-amino-6-hydroxylaminopurine (AHA) and are AHA-hypermutable" Uncharacterized chr10:333352-334089 333352-334089 98.2% 604.21 743.53 611.10 630.42 1241.52 1047.02 673.87 620.76 1144.27 2.49 2.52 4.74 0.88 0.77 Matched[3147]
YJL054W TIM54 Component of the mitochondrial Tim54p-Tim22p complex involved in insertion of polytopic proteins into the inner membrane Verified chr10:334260-335696 334260-335696 98.5% 250.83 243.77 248.71 207.73 158.27 132.83 247.30 228.22 145.55 0.91 0.93 0.60 -0.65 -0.31 Covered/w/another[3148]
YJL053W PEP8 "Vacuolar protein sorting protein that forms part of the multimeric membrane-associated retromer complex along with Vps35p, Vps29p, Vps17p, and Vps5p; essential for endosome-to-Golgi retrograde protein transport" Verified chr10:335893-337032 335893-337032 98.8% 169.66 188.31 184.76 183.87 348.20 252.27 178.99 184.31 300.23 0.66 0.75 1.24 0.70 1.15 Covered/w/another[3148]
YJL052C-A "Putative protein of unknown function, identified based on comparison to related yeast species" Uncharacterized chr10:337879-337998 337879-337998 98.3% 8.48 0.00 25.44 0.00 8.48 8.48 4.24 12.72 8.48 0.02 0.05 0.04 -0.58 0.43
YJL052W TDH1 "Glyceraldehyde-3-phosphate dehydrogenase, isozyme 1, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall" Verified chr10:338266-339264 338266-339264 58.3% 5185.43 27193.01 6475.34 8067.56 13325.13 12524.73 16189.22 7271.45 12924.93 59.76 29.52 53.55 0.83 0.29 Frag>80[3149,3150]
YJL051W "Bud tip localized protein of unknown function; mRNA is targeted to the bud by a She2p dependent transport system; mRNA is cell cycle regulated via Fkh2p, peaking in G2/M phase; null mutant displays increased levels of spontaneous Rad52 foci" Uncharacterized chr10:339782-342250 339782-342250 98.8% 86.05 112.27 93.42 72.12 86.46 86.87 99.16 82.77 86.66 0.37 0.34 0.36 0.07 0.45 Matched[3151]
YJL050W MTR4 "Dead-box family ATP dependent helicase required for mRNA export from the nucleus; co-factor of the exosome complex, required for 3' end formation of 5.8S rRNA" Verified chr10:342517-345738 342517-345738 98.6% 267.27 147.64 184.79 150.48 14.80 4.41 207.46 167.64 9.60 0.77 0.68 0.04 -4.13 -4.32 Matched[3152]
YJL049W Putative protein of unknown function; YJL049W is a non-essential gene Uncharacterized chr10:345968-347320 345968-347320 98.6% 114.66 114.66 121.41 98.93 172.37 77.19 114.66 110.17 124.78 0.42 0.45 0.52 0.18 -0.01 Covered/w/another[3153]
YJL048C UBX6 "UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p, transcription is repressed when cells are grown in media containing inositol and choline" Verified chr10:347442-348632 347442-348632 99.0% 79.75 133.19 82.29 102.65 341.89 226.51 106.47 92.47 284.20 0.39 0.38 1.18 1.62 1.35 Covered/w/another[3153]
YJL047C-A Putative protein of unknown function Uncharacterized chr10:349039-349173 349039-349173 99.2% 104.51 119.44 52.26 52.26 67.19 89.58 111.98 52.26 78.38 0.41 0.21 0.32 0.58 NaN Covered/w/another[3153]
YJL047C RTT101 "Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex; deletion phenotype suggests a role in anaphase progression; interacts with Mms22p and implicated in Mms22-dependent DNA repair; modified by the ubiquitin-like protein, Rub1p" Verified chr10:349575-352103 349575-352103 99.2% 46.63 46.24 37.07 38.66 55.00 47.03 46.44 37.87 51.02 0.17 0.15 0.21 0.43 0.92 Covered/w/another[3153]
YJL046W "Putative protein of unknown function, predicted to encode a lipoate-protein ligase A family member; deletion mutant has a respiratory growth defect" Uncharacterized chr10:352381-353610 352381-353610 98.9% 94.57 93.75 83.88 108.55 164.47 99.51 94.16 96.22 131.99 0.35 0.39 0.55 0.46 0.44 Matched[3154]
YJL045W "Minor succinate dehydrogenase isozyme; homologous to Sdh1p, the major isozyme reponsible for the oxidation of succinate and transfer of electrons to ubiquinone; induced during the diauxic shift in a Cat8p-dependent manner" Uncharacterized chr10:356019-357923 356019-357923 98.4% 14.94 14.94 11.74 12.27 44.29 41.09 14.94 12.01 42.69 0.06 0.05 0.18 1.83 1.24 Matched[3156]
YJL044C GYP6 "GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved in vesicle mediated protein transport" Verified chr10:358295-359671 358295-359671 99.2% 377.15 445.26 330.28 314.90 322.23 290.00 411.20 322.59 306.11 1.52 1.31 1.27 -0.08 0.39 Matched[3158]
YJL043W Putative protein of unknown function; YJL043W is a non-essential gene Uncharacterized chr10:360125-360898 360125-360898 98.4% 22.33 22.33 18.39 5.25 26.27 32.84 22.33 11.82 29.56 0.08 0.05 0.12 1.32 0.54 Covered/w/another[3159]
YJL042W MHP1 Microtubule-associated protein involved in assembly and stabilization of microtubules; overproduction results in cell cycle arrest at G2 phase; similar to Drosophila protein MAP and to mammalian MAP4 proteins Verified chr10:361244-365440 361244-365440 98.6% 145.43 187.95 170.56 176.84 230.71 401.26 166.69 173.70 315.99 0.62 0.71 1.31 0.86 1.79 Covered/w/another[3159]
YJL041W NSP1 "Essential component of the nuclear pore complex, which mediates nuclear import and export" Verified chr10:365779-368368 365779-365779,365898-368368 81.9% 293.48 275.69 278.66 258.89 155.14 124.51 284.58 268.77 139.82 1.05 1.09 0.58 -0.94 -0.31 Frag>80[3160,3161,3162,3163]
YJL039C NUP192 "Essential structural subunit of the nuclear pore complex (NPC), localizes to the nuclear periphery of nuclear pores, homologous to human p205" Verified chr10:368743-373794 368743-373794 99.1% 123.24 97.87 95.67 89.88 41.55 53.53 110.55 92.78 47.54 0.41 0.38 0.20 -0.96 -0.49 Frag>80[3164,3165,3166]
YJL038C "Putative protein of unknown function; expression induced during sporulation and repressed during vegetative growth by Sum1p and Hst1p; similar to adjacent open reading frame, YJL037W" Uncharacterized chr10:375110-375769 375110-375769 99.4% 30.47 24.38 24.38 12.19 27.43 12.19 27.43 18.28 19.81 0.10 0.07 0.08 0.12 0.15
YJL037W "Putative protein of unknown function; expression induced in respiratory-deficient cells and in carbon-limited chemostat cultures; similar to adjacent ORF, YJL038C; null mutant displays increased levels of spontaneous Rad52 foci" Uncharacterized chr10:376657-377331 376657-377331 98.5% 6.01 3.01 3.01 4.51 21.05 15.03 4.51 3.76 18.04 0.02 0.02 0.07 2.26 0.36 Frag<80[3167]
YJL036W SNX4 "Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golgi endosome to the trans-Golgi network and in cytoplasm to vacuole transport; contains a PX domain; forms complex with Snx41p and Atg20p" Verified chr10:378820-380091 378820-380091 98.7% 144.20 152.17 168.90 182.44 317.88 258.12 148.18 175.67 288.00 0.55 0.71 1.19 0.71 0.96 Matched[3168]
YJL035C TAD2 "Subunit of tRNA-specific adenosine-34 deaminase, forms a heterodimer with Tad3p that converts adenosine to inosine at the wobble position of several tRNAs" Verified chr10:380244-380996 380244-380996 99.2% 103.04 53.53 89.66 42.82 173.97 89.66 78.29 66.24 131.82 0.29 0.27 0.55 0.99 1.48 Matched[3169]
YJL034W KAR2 "ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p" Verified chr10:381322-383370 381322-383370 97.7% 1575.83 1092.84 1554.35 1333.08 10162.20 8671.79 1334.33 1443.72 9416.99 4.93 5.86 39.02 2.71 2.30 Matched[3170]
YJL033W HCA4 Putative nucleolar DEAD box RNA helicase; high-copy number suppression of a U14 snoRNA processing mutant suggests an involvement in 18S rRNA synthesis Verified chr10:383832-386144 383832-386144 98.6% 210.05 100.86 101.30 80.69 12.28 4.82 155.46 90.99 8.55 0.57 0.37 0.04 -3.41 -2.77 Matched[3171]
YJL032W Dubious open reading frame unlikely to encode a functional protein; overlaps 3' end of essential BET4 gene encoding the alpha subunit of Type II geranylgeranyltransferase Dubious chr10:386343-386657 386343-386657 99.4% 223.46 201.12 185.16 217.08 472.47 255.39 212.29 201.12 363.93 0.78 0.82 1.51 0.86 -0.01 Matched[3172]
YJL031C BET4 Alpha subunit of Type II geranylgeranyltransferase required for vesicular transport between the endoplasmic reticulum and the Golgi; provides a membrane attachment moiety to Rab-like proteins Ypt1p and Sec4p Verified chr10:386363-387433 386363-387343,387431-387433 99.5% 170.51 142.94 150.09 178.68 374.71 222.58 156.73 164.38 298.65 0.58 0.67 1.24 0.86 0.53 Frag>80[3172,3173]
YJL030W MAD2 "Component of the spindle-assembly checkpoint complex, which delays the onset of anaphase in cells with defects in mitotic spindle assembly; forms a complex with Mad1p" Verified chr10:387652-388242 387652-388242 98.6% 209.35 193.91 187.04 169.88 327.76 247.10 201.63 178.46 287.43 0.74 0.72 1.19 0.69 0.59 Covered/w/another[3174]
YJL029C VPS53 "Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; required for vacuolar protein sorting" Verified chr10:388380-390848 388380-390848 99.0% 148.89 148.48 132.53 130.08 142.35 133.35 148.69 131.30 137.85 0.55 0.53 0.57 0.07 0.36 Covered/w/another[3174]
YJL028W "Protein of unknown function; may interact with ribosomes, based on co-purification experiments" Verified chr10:391306-391641 391306-391641 98.9% 6.02 3.01 0.00 3.01 0.00 9.02 4.51 1.50 4.51 0.02 0.01 0.02 1.58 0.15
YJL027C Putative protein of unknown function Uncharacterized chr10:391828-392244 391828-392244 98.2% 4.88 17.09 4.88 4.88 4.88 9.77 10.99 4.88 7.33 0.04 0.02 0.03 0.58 0.76 Overlap[3175]
YJL026W RNR2 "Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits" Verified chr10:392399-393598 392399-393598 98.7% 1452.09 1937.53 1446.18 1459.69 1187.84 1049.39 1694.81 1452.93 1118.62 6.26 5.90 4.63 -0.38 -0.06 Matched[3175]
YJL026C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene YJL026W/RNR2" Dubious chr10:393061-393282 393061-393282 98.8% 1649.83 2014.43 1590.58 1718.19 1321.69 1194.08 1832.13 1654.39 1257.88 6.76 6.72 5.21 -0.40 NaN Covered/w/another[3175]
YJL025W RRN7 "Protein involved in the transcription of 35S rRNA genes by RNA polymerase I; component of the core factor (CF) complex also composed of Rrn11p, Rrn6p and TATA-binding protein" Verified chr10:393962-395506 393962-395506 98.8% 58.95 75.98 49.12 40.61 24.89 38.64 67.46 44.87 31.77 0.25 0.18 0.13 -0.50 0.10 Matched[3176]
YJL024C APS3 "Small subunit of the clathrin-associated adaptor complex AP-3, which is involved in vacuolar protein sorting; related to the sigma subunit of the mammalian clathrin AP-3 complex; suppressor of loss of casein kinase 1 function" Verified chr10:395926-396587 395926-396488,396566-396587 99.2% 165.51 146.54 158.61 122.40 201.71 177.57 156.02 140.51 189.64 0.58 0.57 0.79 0.43 0.17 Matched[3177]
YJL022W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene PET130" Dubious chr10:398104-398412 398104-398412 99.2% 52.20 68.51 32.62 19.57 52.20 29.36 60.35 26.10 40.78 0.22 0.11 0.17 0.64 0.80 Covered/w/another[3178]
YJL023C PET130 "Protein required for respiratory growth; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr10:397350-398393 397350-398393 99.3% 72.33 79.08 72.33 46.29 96.44 54.97 75.70 59.31 75.70 0.28 0.24 0.31 0.35 0.52 Matched[3178]
YJL020W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene YJL020C/BBC1" Dubious chr10:400976-401233 400976-401233 99.4% 183.33 198.93 226.23 214.53 234.03 460.26 191.13 220.38 347.15 0.71 0.89 1.44 0.66 NaN Covered/w/another[3179]
YJL020C BBC1 Protein possibly involved in assembly of actin patches; interacts with an actin assembly factor Las17p and with the SH3 domains of Type I myosins Myo3p and Myo5p; localized predominantly to cortical actin patches Verified chr10:398932-402405 398932-402405 97.7% 241.78 308.92 281.83 282.42 386.66 567.78 275.35 282.12 477.22 1.02 1.15 1.98 0.76 1.62 Matched[3179]
YJL019W MPS3 "Essential integral membrane protein required for spindle pole body duplication and for nuclear fusion, localizes to the spindle pole body half bridge, interacts with DnaJ-like chaperone Jem1p and with centrin homolog Cdc31p" Verified chr10:402892-404940 402892-404940 98.7% 76.16 54.90 61.33 53.41 25.72 26.71 65.53 57.37 26.21 0.24 0.23 0.11 -1.13 -0.25 Matched[3180]
YJL016W Putative protein of unknown function; GFP-fusion protein localizes to the cytoplasm; conserved in closely related Saccharomyces species Uncharacterized chr10:405583-407268 405583-407268 99.0% 161.22 221.76 130.06 103.69 443.51 286.48 191.49 116.87 365.00 0.71 0.47 1.51 1.64 1.74 Matched[3181]
YJL015C "Dubious open reading frame unlikely to encode a functional protein; expression if heat-inducible; located in promoter region of essential CCT3 gene encoding a subunit of the cytosolic chaperonin Cct ring complex, overlaps ORF YJL016W" Dubious chr10:407137-407511 407137-407511 99.3% 110.05 174.48 123.48 77.84 370.43 185.21 142.27 100.66 277.82 0.53 0.41 1.15 1.46 0.25 Overlap[3181,3182]
YJL014W CCT3 "Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo" Verified chr10:407552-409156 407552-409156 98.6% 543.37 332.34 428.38 410.69 278.64 199.03 437.86 419.53 238.83 1.62 1.70 0.99 -0.81 -0.68 Matched[3182]
YJL013C MAD3 "Subunit of the spindle-assembly checkpoint complex, which delays anaphase onset in cells with defects in mitotic spindle assembly; pseudosubstrate inhibitor of APC(Cdc20), the anaphase promoting complex involved in securin (Pds1p) turnover" Verified chr10:409487-411034 409487-411034 99.4% 89.72 109.22 104.02 79.32 122.23 74.77 99.47 91.67 98.50 0.37 0.37 0.41 0.10 0.30 Matched[3183]
YJL012C VTC4 Vacuolar membrane protein involved in vacuolar polyphosphate accumulation; functions as a regulator of vacuolar H+-ATPase activity and vacuolar transporter chaperones; involved in non-autophagic vacuolar fusion Verified chr10:411228-413393 411228-413393 99.2% 1145.30 968.38 1182.54 1083.38 432.98 356.16 1056.84 1132.96 394.57 3.90 4.60 1.63 -1.52 -0.97 Frag>80[3184,3185]
YJL011C RPC17 "RNA polymerase III subunit C17; physically interacts with C31, C11, and TFIIIB70; may be involved in the recruitment of pol III by the preinitiation complex" Verified chr10:414279-414764 414279-414764 99.4% 146.97 109.71 124.20 76.59 14.49 16.56 128.34 100.40 15.53 0.47 0.41 0.06 -2.69 -2.21 Matched[3186]
YJL010C Essential nucleolar protein required for 18S rRNA synthesis Uncharacterized chr10:417556-419556 417556-419556 99.3% 154.00 96.13 107.20 86.06 12.58 14.09 125.07 96.63 13.34 0.46 0.39 0.06 -2.86 -2.48 Matched[3188]
YJL009W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps CCT8/YJL008C, a verified gene encoding a subunit of the cytosolic chaperonin Cct ring complex" Dubious chr10:419849-420175 419849-420175 99.4% 886.49 671.03 652.56 606.39 504.81 313.97 778.76 629.47 409.39 2.87 2.56 1.70 -0.62 -0.03 Matched[3189]
YJL008C CCT8 "Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo" Verified chr10:419951-421657 419951-421657 99.2% 539.84 382.14 472.51 430.58 259.29 235.07 460.99 451.54 247.18 1.70 1.83 1.02 -0.87 -0.51 Frag>80[3189,3190]
YJL007C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr10:422692-423006 422692-423006 81.9% 15.51 11.63 0.00 3.88 3.88 0.00 13.57 1.94 1.94 0.05 0.01 0.01 0.00 0.04
YJL006C CTK2 "Beta subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates the C-terminal repeated domain of the RNA polymerase II large subunit (Rpo21p) to affect both transcription and pre-mRNA 3' end processing; has similarity to cyclins" Verified chr10:423132-424103 423132-424103 99.2% 87.10 68.43 69.47 50.81 61.17 42.51 77.76 60.14 51.84 0.29 0.24 0.21 -0.21 -0.26 Matched[3192]
YJL005W CYR1 "Adenylate cyclase, required for cAMP production and cAMP-dependent protein kinase signaling; the cAMP pathway controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation" Verified chr10:425151-431231 425151-431231 98.8% 106.00 153.25 114.15 117.31 144.93 238.61 129.62 115.73 191.77 0.48 0.47 0.79 0.73 0.83 Frag>80[3193,3194]
YJL004C SYS1 Integral membrane protein of the Golgi required for targeting of the Arf-like GTPase Arl3p to the Golgi; multicopy suppressor of ypt6 null mutation Verified chr10:431583-432194 431583-432194 99.1% 229.14 225.84 245.62 173.09 253.86 153.31 227.49 209.36 203.59 0.84 0.85 0.84 -0.04 -0.53 Matched[3195]
YJL003W COX16 "Mitochondrial inner membrane protein, required for assembly of cytochrome c oxidase" Verified chr10:432638-432994 432638-432994 98.5% 218.93 261.58 233.15 244.52 446.39 326.98 240.26 238.83 386.68 0.89 0.97 1.60 0.70 0.01 Matched[3197]
YJL002C OST1 "Alpha subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins" Verified chr10:433215-434645 433215-434645 98.8% 956.12 894.60 956.83 955.42 580.61 461.80 925.36 956.12 521.20 3.42 3.88 2.16 -0.88 -0.27 Matched[3198]
YJL001W PRE3 "20S proteasome beta-type subunit, responsible for cleavage after acidic residues in peptides" Verified chr10:435157-435920 435157-435221,435338-435920 98.8% 771.87 626.56 779.69 695.31 1501.56 781.25 699.22 737.50 1141.41 2.58 2.99 4.73 0.63 0.29 Matched[3200]
YJR001W AVT1 "Vacuolar transporter, imports large neutral amino acids into the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters" Verified chr10:436796-438604 436796-438604 98.9% 314.20 350.54 304.14 276.74 246.55 171.64 332.37 290.44 209.09 1.23 1.18 0.87 -0.47 -0.41 Matched[3202]
YJR002W MPP10 "Component of the SSU processome, which is required for pre-18S rRNA processing, interacts with and controls the stability of Imp3p and Imp4p, essential for viability; similar to human Mpp10p" Verified chr10:438858-440639 438858-440639 98.4% 267.55 144.33 190.54 139.20 31.38 11.98 205.94 164.87 21.68 0.76 0.67 0.09 -2.93 -2.60 Frag>80[3203]
YJR003C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr10:440987-442546 440987-442546 99.2% 155.14 132.51 120.88 100.19 31.67 26.50 143.83 110.54 29.09 0.53 0.45 0.12 -1.93 -1.78 Matched[3204]
YJR004C SAG1 "Alpha-agglutinin of alpha-cells, binds to Aga1p during agglutination, N-terminal half is homologous to the immunoglobulin superfamily and contains binding site for a-agglutinin, C-terminal half is highly glycosylated and contains GPI anchor" Verified chr10:442902-444854 442902-444854 98.7% 91.80 95.95 78.32 54.98 46.68 36.31 93.88 66.65 41.49 0.35 0.27 0.17 -0.68 0.12 Matched[3205]
YJR005W APL1 "Beta-adaptin, large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport; similar to mammalian beta-chain of the clathrin associated protein complex" Verified chr10:445916-448018 445916-448018 99.0% 154.18 141.69 140.25 128.24 146.02 122.48 147.94 134.25 134.25 0.55 0.54 0.56 0.00 0.20 Matched[3206]
YJR005C-A "Putative protein of unknown function, originally identified as a syntenic homolog of an Ashbya gossypii gene" Uncharacterized chr10:448470-448751 448470-448751 99.6% 0.00 3.56 0.00 0.00 92.55 32.04 1.78 0.00 62.30 0.01 0.00 0.26 Inf NaN Matched[3207]
YJR006W POL31 "DNA polymerase III (delta) subunit, essential for cell viability; involved in DNA replication and DNA repair" Verified chr10:449195-450658 449195-450658 98.7% 154.34 175.80 155.73 131.50 198.64 157.80 165.07 143.62 178.22 0.61 0.58 0.74 0.31 0.38 Matched[3208]
YJR007W SUI2 "Alpha subunit of the translation initiation factor eIF2, involved in the identification of the start codon; phosphorylation of Ser51 is required for regulation of translation by inhibiting the exchange of GDP for GTP" Verified chr10:451013-451927 451013-451927 98.9% 781.22 622.10 741.44 664.09 339.23 232.04 701.66 702.76 285.64 2.59 2.85 1.18 -1.30 -0.97 Matched[3209]
YJR008W Putative protein of unknown function; expression repressed by inosine and choline in an Opi1p-dependent manner; expression induced by mild heat-stress on a non-fermentable carbon source. Uncharacterized chr10:452423-453439 452423-453439 98.7% 84.66 164.35 104.59 101.60 747.04 539.86 124.51 103.09 643.45 0.46 0.42 2.67 2.64 1.49 Matched[3210]
YJR009C TDH2 "Glyceraldehyde-3-phosphate dehydrogenase, isozyme 2, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall" Verified chr10:453676-454674 453676-454674 26.4% 27861.41 29213.10 25226.39 22344.57 9484.58 6109.16 28537.26 23785.47 7796.87 105.34 96.55 32.31 -1.61 -1.90 Frag>80[3211,3212]
YJR010W MET3 "ATP sulfurylase, catalyzes the primary step of intracellular sulfate activation, essential for assimilatory reduction of sulfate to sulfide, involved in methionine metabolism" Verified chr10:456232-457767 456232-457767 98.8% 65.21 85.63 67.18 41.50 65.87 42.15 75.42 54.34 54.01 0.28 0.22 0.22 -0.01 0.23 Matched[3214]
YJR010C-A SPC1 "Subunit of the signal peptidase complex (SPC), which cleaves the signal sequence from proteins targeted to the endoplasmic reticulum (ER), homolog of the SPC12 subunit of mammalian signal peptidase complex" Verified chr10:458070-458354 458070-458354 99.0% 272.77 343.62 311.73 304.65 240.89 233.80 308.19 308.19 237.34 1.14 1.25 0.98 -0.38 -0.66 Matched[3215]
YJR011C Putative protein of unknown function; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS Uncharacterized chr10:458634-459419 458634-459419 99.5% 67.80 83.15 62.68 72.91 70.35 86.98 75.47 67.80 78.67 0.28 0.28 0.33 0.21 0.58 Covered/w/another[3216]
YJR013W GPI14 "Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I, involved in GPI anchor biosynthesis, requires Pbn1p for function; homolog of mammalian PIG-M" Verified chr10:460375-461586 460375-461586 99.0% 165.07 170.07 188.41 161.73 142.56 95.04 167.57 175.07 118.80 0.62 0.71 0.49 -0.56 -0.47 Covered/w/another[3216]
YJR012C "Putative protein of unknown function; proposed involvement in transport based on mass spectrometry analysis of copurifying proteins; partially overlaps neighboring ORF, GPI14/YJR013W" Uncharacterized chr10:459788-460411 459788-460411 99.1% 95.45 127.81 118.10 118.10 122.95 88.98 111.63 118.10 105.97 0.41 0.48 0.44 -0.16 -0.10 Covered/w/another[3216]
YJR014W TMA22 "Protein of unknown function that associates with ribosomes and has a putative RNA binding domain; interacts with Tma20p; has homology to human protein DRP1, which interacts with human Tma20p homolog MCT-1" Verified chr10:461822-462418 461822-462418 98.2% 837.94 684.35 694.59 650.22 657.04 505.16 761.15 672.40 581.10 2.81 2.73 2.41 -0.21 0.17 Matched[3217]
YJR015W Putative protein of unknown function; localizes to the endoplasmic reticulum and cytoplasm; predicted to encode a membrane transporter based on phylogenetic analysis; YJR015W is a non-essential gene Uncharacterized chr10:462714-464246 462714-464246 98.9% 526.83 539.36 502.43 489.24 307.92 258.47 533.09 495.84 283.19 1.97 2.01 1.17 -0.81 -0.60 Matched[3218]
YJR016C ILV3 "Dihydroxyacid dehydratase, catalyzes third step in the common pathway leading to biosynthesis of branched-chain amino acids" Verified chr10:464444-466201 464444-466201 98.8% 1392.20 1578.67 1152.20 1207.45 142.15 101.29 1485.43 1179.83 121.72 5.48 4.79 0.50 -3.28 -2.13 Matched[3219]
YJR018W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr10:466779-467141 466779-467141 98.6% 438.65 508.50 435.86 455.41 444.24 424.68 473.57 445.63 434.46 1.75 1.81 1.80 -0.04 -0.13 Frag<80[3220]
YJR017C ESS1 Peptidylprolyl-cis/trans-isomerase (PPIase) specific for phosphorylated serine and threonine residues N-terminal to proline; regulates phosphorylation of the RNA polymerase II large subunit (Rpo21p) C-terminal domain Verified chr10:466514-467026 466514-467026 98.7% 630.12 782.22 630.12 669.63 641.98 653.83 706.17 649.88 647.90 2.61 2.64 2.68 -0.00 0.36 Matched[3220]
YJR020W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr10:467994-468326 467994-468326 98.5% 33.55 70.15 51.85 57.95 76.25 61.00 51.85 54.90 68.62 0.19 0.22 0.28 0.32 0.27 Covered/w/another[3221]
YJR019C TES1 Peroxisomal acyl-CoA thioesterase likely to be involved in fatty acid oxidation rather than fatty acid synthesis; conserved protein also found in human peroxisomes; TES1 mRNA levels increase during growth on fatty acids Verified chr10:467225-468274 467225-468274 98.3% 66.83 89.11 79.42 85.23 116.23 84.26 77.97 82.33 100.25 0.29 0.33 0.42 0.28 0.72 Covered/w/another[3221]
YJR021C REC107 Protein involved in early stages of meiotic recombination; involved in coordination between the initiation of recombination and the first division of meiosis; part of a complex (Rec107p-Mei4p-Rec114p) required for ds break formation Verified chr10:468548-469572 468548-469176,469257-469572 99.0% 125.07 145.38 126.14 94.07 222.34 160.34 135.22 110.10 191.34 0.50 0.45 0.79 0.80 0.82 Covered/w/another[3221]
YJR022W LSM8 "Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) that is part of spliceosomal U6 snRNP and is also implicated in processing of pre-tRNA, pre-snoRNA, and pre-rRNA" Verified chr10:469777-470106 469777-470106 98.7% 122.79 113.58 141.21 76.75 196.47 174.98 118.19 108.98 185.73 0.44 0.44 0.77 0.77 0.21 Matched[3222]
YJR023C Putative protein of unknown function; open reading frame overlaps LSM8/YJR022W encoding an essential snRNP protein required for RNA processing and splicing Dubious chr10:469797-470198 469797-470198 90.2% 121.37 96.54 159.98 88.27 193.08 159.98 108.95 124.12 176.53 0.40 0.50 0.73 0.51 0.29 Matched[3222]
YJR024C Putative methylthio-ribulose-1-phosphate dehydratase; acts in the methionine salvage pathway; potential Smt3p sumoylation substrate; expression downregulated by caspofungin and deletion mutant is caspofungin resistant Uncharacterized chr10:470223-470957 470223-470957 99.0% 311.92 237.72 309.17 252.83 252.83 185.50 274.82 281.00 219.17 1.01 1.14 0.91 -0.36 -0.72 Matched[3223]
YJR025C BNA1 "3-hydroxyanthranilic acid dioxygenase, required for biosynthesis of nicotinic acid from tryptophan via kynurenine pathway" Verified chr10:471131-471664 471131-471664 99.3% 760.20 1480.78 752.65 811.13 1165.76 773.40 1120.49 781.89 969.58 4.14 3.17 4.02 0.31 -0.07 Matched[3224]
YJR030C Putative protein of unknown function; expression repressed in carbon limited vs carbon replete chemostat cultures; YJR030C is a non-essential gene Uncharacterized chr10:483952-486189 483952-486189 99.0% 129.02 123.61 107.82 87.52 64.06 60.00 126.32 97.67 62.03 0.47 0.40 0.26 -0.65 0.24 Matched[3227]
YJR031C GEA1 "Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; similar to but not functionally redundant with Gea2p" Verified chr10:486579-490805 486579-490805 99.2% 62.74 67.28 48.43 55.83 22.19 19.56 65.01 52.13 20.87 0.24 0.21 0.09 -1.32 -0.96 Matched[3228]
YJR032W CPR7 "Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity" Verified chr10:491074-492255 491074-492255 98.7% 160.31 150.03 147.45 169.74 137.17 93.45 155.17 158.60 115.31 0.57 0.64 0.48 -0.46 -0.43 Covered[3229]
YJR033C RAV1 "Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of the V-ATPase holoenzyme; required for transport between the early and late endosome/PVC and for localization of TGN membrane proteins; potential Cdc28p substrate" Verified chr10:492371-496444 492371-496444 99.1% 67.16 90.45 75.33 75.33 88.96 103.58 78.80 75.33 96.27 0.29 0.31 0.40 0.35 0.76 Frag<80[3230,3231]
YJR034W PET191 "Protein required for assembly of cytochrome c oxidase; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr10:496676-497002 496676-497002 98.3% 242.61 214.62 233.28 217.73 348.37 223.95 228.62 225.51 286.16 0.84 0.92 1.19 0.34 -0.24 Matched[3231]
YJR035W RAD26 Protein involved in transcription-coupled repair nucleotide excision repair of UV-induced DNA lesions; homolog of human CSB protein Verified chr10:497348-500605 497348-500605 98.5% 49.84 57.94 41.43 40.81 57.32 58.57 53.89 41.12 57.94 0.20 0.17 0.24 0.49 1.11 Covered/w/another[3232]
YJR037W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene HUL4/YJR036C; YJR037W is not an essential gene." Dubious chr10:503095-503478 503095-503478 99.0% 10.53 34.21 15.79 13.16 65.79 52.63 22.37 14.47 59.21 0.08 0.06 0.25 2.03 0.10 Covered/w/another[3232]
YJR036C HUL4 "Protein with similarity to hect domain E3 ubiquitin-protein ligases, not essential for viability" Verified chr10:500706-503384 500706-503384 99.3% 20.67 33.45 29.70 28.94 114.27 94.72 27.06 29.32 104.50 0.10 0.12 0.43 1.83 1.69 Covered/w/another[3232]
YJR039W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr10:503929-507294 503929-507294 98.8% 33.36 47.49 39.07 31.86 91.07 76.64 40.43 35.47 83.86 0.15 0.14 0.35 1.24 1.09 Covered/w/another[3232]
YJR038C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr10:503703-504065 503703-504065 97.8% 19.72 19.72 14.08 14.08 45.07 42.25 19.72 14.08 43.66 0.07 0.06 0.18 1.63 1.74 Covered/w/another[3232]
YJR040W GEF1 "Chloride channel localized to late- or post-Golgi vesicles, involved in iron metabolism; highly homologous to voltage-gated chloride channels in vertebrates" Verified chr10:507739-510078 507739-510078 98.8% 136.31 140.21 138.91 106.46 124.63 97.37 138.26 122.68 111.00 0.51 0.50 0.46 -0.14 0.21 Matched[3233]
YJR041C URB2 "Nucleolar protein required for normal metabolism of the rRNA primary transcript, proposed to be involved in ribosome biogenesis" Verified chr10:510232-513756 510232-513756 99.1% 100.17 62.10 62.68 55.52 6.87 1.72 81.14 59.10 4.29 0.30 0.24 0.02 -3.78 -2.76 Frag>80[3234,3235]
YJR042W NUP85 "Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), required for assembly of the subcomplex and also for formation of the nucleocytoplasmic Gsp1p concentration gradient that plays a role in nuclear trafficking" Verified chr10:514048-516282 514048-516282 98.7% 192.67 153.68 160.93 147.79 91.57 79.33 173.17 154.36 85.45 0.64 0.63 0.35 -0.85 -0.41 Matched[3236]
YJR043C POL32 "Third subunit of DNA polymerase delta, involved in chromosomal DNA replication; required for error-prone DNA synthesis in the presence of DNA damage and processivity; interacts with Hys2p, PCNA (Pol30p), and Pol1p" Verified chr10:516454-517506 516454-517506 99.2% 194.37 139.80 131.18 126.39 67.03 37.34 167.09 128.79 52.18 0.62 0.52 0.22 -1.30 -0.89 Matched[3237]
YJR044C VPS55 Late endosomal protein involved in late endosome to vacuole trafficking; functional homolog of human obesity receptor gene-related protein (OB-RGRP) Verified chr10:518756-519178 518756-519178 98.8% 492.82 497.61 564.59 516.75 767.94 409.09 495.22 540.67 588.52 1.83 2.19 2.44 0.12 0.20 Frag>80[3238,3239,3240,3241]
YJR045C SSC1 "Mitochondrial matrix ATPase, subunit of the presequence translocase-associated protein import motor (PAM) and of SceI endonuclease; involved in protein folding and translocation into the matrix; phosphorylated; member of HSP70 family" Verified chr10:519631-521595 519631-521595 98.5% 2282.84 2168.67 2476.04 2424.38 7262.82 7950.41 2225.75 2450.21 7606.61 8.22 9.95 31.52 1.63 1.37 Frag>80[3240,3241,3242]
YJR046W TAH11 "DNA replication licensing factor, required for pre-replication complex assembly" Verified chr10:522041-523855 522041-523855 98.6% 135.27 136.95 116.83 97.26 836.24 633.33 136.11 107.05 734.79 0.50 0.43 3.04 2.78 2.70 Matched[3243]
YJR047C ANB1 "Translation initiation factor eIF-5A, promotes formation of the first peptide bond; similar to and functionally redundant with Hyp2p; undergoes an essential hypusination modification; expressed under anaerobic conditions" Verified chr10:524901-525374 524901-525374 76.8% 192.22 2583.98 167.51 186.73 189.47 236.16 1388.10 177.12 212.81 5.12 0.72 0.88 0.26 0.20 Matched[3245]
YJR048W CYC1 "Cytochrome c, isoform 1; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration" Verified chr10:526328-526657 526328-526657 91.2% 262.35 152.76 282.27 222.50 109.59 116.23 207.55 252.39 112.91 0.77 1.02 0.47 -1.16 -0.96 Matched[3246]
YJR049C UTR1 ATP-NADH kinase; phosphorylates both NAD and NADH; active as a hexamer; enhances the activity of ferric reductase (Fre1p) Verified chr10:526877-528469 526877-528469 99.1% 257.15 307.18 238.78 226.11 342.02 277.41 282.16 232.44 309.71 1.04 0.94 1.28 0.41 0.68 Covered/w/another[3247]
YJR050W ISY1 "Component of the spliceosome complex involved in pre-mRNA splicing, auxiliary splicing factor that may modulate Syf1p activity and help optimize splicing; isy1 syf2 double mutation activates the spindle checkpoint, causing cell cycle arrest" Verified chr10:528690-529397 528690-529397 98.2% 136.59 159.60 122.21 130.84 162.47 100.65 148.09 126.53 131.56 0.55 0.51 0.55 0.06 0.07 Covered/w/another[3247]
YJR051W OSM1 "Fumarate reductase, catalyzes the reduction of fumarate to succinate, required for the reoxidation of intracellular NADH under anaerobic conditions; mutations cause osmotic sensitivity" Verified chr10:529854-531359 529854-531359 98.8% 207.74 248.07 219.84 253.45 252.78 227.91 227.91 236.65 240.34 0.84 0.96 1.00 0.02 0.45 Matched[3248]
YJR052W RAD7 Protein that recognizes and binds damaged DNA in an ATP-dependent manner (with Rad16p) during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex Verified chr10:532055-533752 532055-533752 98.6% 75.24 61.50 69.27 66.28 134.35 111.66 68.37 67.77 123.01 0.25 0.28 0.51 0.86 1.12 Matched[3249]
YJR053W BFA1 Component of the GTPase-activating Bfa1p-Bub2p complex involved in multiple cell cycle checkpoint pathways that control exit from mitosis Verified chr10:534020-535744 534020-535744 98.6% 16.46 26.45 15.87 19.98 18.22 22.92 21.45 17.93 20.57 0.08 0.07 0.09 0.20 0.85 Covered/w/another[3250]
YJR054W Vacuolar protein of unknown function; potential Cdc28p substrate Uncharacterized chr10:536049-537542 536049-537542 99.0% 133.89 123.74 121.71 122.39 65.59 56.12 128.81 122.05 60.86 0.48 0.50 0.25 -1.00 -0.33 Covered/w/another[3250]
YJR055W HIT1 "Protein of unknown function, required for growth at high temperature" Verified chr10:538765-539259 538765-539259 98.7% 53.22 57.32 57.32 38.89 49.13 8.19 55.27 48.11 28.66 0.20 0.20 0.12 -0.75 -0.99 Covered[3251]
YJR056C Hypothetical protein Uncharacterized chr10:541785-542495 541785-542495 99.3% 94.88 89.22 107.63 83.55 196.85 165.69 92.05 95.59 181.27 0.34 0.39 0.75 0.92 1.22 Matched[3253]
YJR057W CDC8 "Thymidylate and uridylate kinase, functions in de novo biosynthesis of pyrimidine deoxyribonucleotides; converts dTMP to dTDP and dUMP to dUTP; essential for mitotic and meiotic DNA replication; homologous to S. pombe Tmp1p" Verified chr10:544055-544705 544055-544705 98.6% 202.48 183.79 186.90 138.62 186.90 96.57 193.13 162.76 141.74 0.71 0.66 0.59 -0.20 -0.49 Matched[3254]
YJR058C APS2 "Small subunit of the clathrin-associated adaptor complex AP-2, which is involved in protein sorting at the plasma membrane; related to the sigma subunit of the mammalian plasma membrane clathrin-associated protein (AP-2) complex" Verified chr10:544725-545168 544725-545168 99.2% 326.81 365.39 272.34 201.99 603.69 254.18 346.10 237.16 428.94 1.28 0.96 1.78 0.85 -0.06 Matched[3254]
YJR059W PTK2 Putative serine/threonine protein kinase involved in regulation of ion transport across plasma membrane; enhances spermine uptake Verified chr10:545780-548236 545780-548236 98.7% 223.12 273.84 345.19 338.59 612.43 815.34 248.48 341.89 713.89 0.92 1.39 2.96 1.06 1.83 Matched[3255]
YJR060W CBF1 "Helix-loop-helix protein that binds the motif CACRTG, which is present at several sites including MET gene promoters and centromere DNA element I (CDEI); required for nucleosome positioning at this motif; targets Isw1p to DNA" Verified chr10:548752-549807 548752-549807 97.9% 218.60 192.49 218.60 235.05 226.34 222.47 205.55 226.83 224.41 0.76 0.92 0.93 -0.02 0.59 Matched[3256]
YJR061W "Putative protein of unknown function; non-essential gene with similarity to Mnn4, a putative membrane protein involved in glycosylation; transcription repressed by Rm101p" Uncharacterized chr10:550504-553311 550504-553311 98.8% 59.81 68.82 48.64 27.74 83.23 49.00 64.32 38.19 66.12 0.24 0.16 0.27 0.79 -0.35 Frag>80[3257]
YJR062C NTA1 "Amidase, removes the amide group from N-terminal asparagine and glutamine residues to generate proteins with N-terminal aspartate and glutamate residues that are targets of ubiquitin-mediated degradation" Verified chr10:553469-554842 553469-554842 99.3% 137.82 139.28 141.48 151.01 255.11 219.92 138.55 146.25 237.51 0.51 0.59 0.98 0.70 1.09 Matched[3258]
YJR063W RPA12 "RNA polymerase I subunit A12.2; contains two zinc binding domains, and the N terminal domain is responsible for anchoring to the RNA pol I complex" Verified chr10:555188-555565 555188-555565 98.8% 425.85 281.22 321.39 238.37 18.75 40.17 353.53 279.88 29.46 1.31 1.14 0.12 -3.25 -3.00 Matched[3259]
YJR064W CCT5 "Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo" Verified chr10:555907-557595 555907-557595 98.7% 679.13 536.95 598.14 524.95 325.77 218.38 608.04 561.54 272.07 2.24 2.28 1.13 -1.05 -1.07 Matched[3260]
YJR065C ARP3 "Essential component of the Arp2/3 complex, which is a highly conserved actin nucleation center required for the motility and integrity of actin patches; involved in endocytosis and membrane growth and polarity" Verified chr10:557802-559151 557802-559151 98.8% 662.00 778.21 713.73 686.74 1011.37 908.66 720.10 700.24 960.01 2.66 2.84 3.98 0.46 0.73 Matched[3261]
YJR066W TOR1 "PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that controls growth in response to nutrients by regulating translation, transcription, ribosome biogenesis, nutrient transport and autophagy; involved in meiosis" Verified chr10:559409-566821 559409-566821 98.8% 52.03 59.27 48.48 51.49 32.50 94.92 55.65 49.98 63.71 0.21 0.20 0.26 0.35 0.42 Matched[3262]
YJR067C YAE1 Essential protein of unknown function Verified chr10:567012-567437 567012-567437 99.5% 141.58 108.54 122.70 89.67 96.75 68.43 125.06 106.18 82.59 0.46 0.43 0.34 -0.36 -0.56 Covered/w/another[3262]
YJR068W RFC2 "Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon" Verified chr10:567636-568697 567636-568697 98.8% 351.67 261.13 270.66 252.55 215.38 169.64 306.40 261.61 192.51 1.13 1.06 0.80 -0.44 -0.72 Matched[3263]
YJR069C HAM1 "Conserved protein with deoxyribonucleoside triphosphate pyrophosphohydrolase activity, mediates exclusion of noncanonical purines from deoxyribonucleoside triphosphate pools; mutant is sensitive to the base analog 6-N-hydroxylaminopurine" Verified chr10:568799-569392 568799-569392 99.1% 404.13 378.66 385.45 366.78 186.78 140.94 391.40 376.11 163.86 1.44 1.53 0.68 -1.20 -1.04 Covered/w/another[3263]
YJR071W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr10:570398-570766 570398-570766 99.3% 455.92 319.42 360.37 253.90 38.22 32.76 387.67 307.13 35.49 1.43 1.25 0.15 -3.11 -2.10 Matched[3265]
YJR070C LIA1 "Deoxyhypusine hydroxylase, a HEAT-repeat containing metalloenzyme that catalyses hypusine formation; binds to and is required for the modification of Hyp2p (eIF5A); complements S. pombe mmd1 mutants defective in mitochondrial positioning" Verified chr10:569614-570591 569614-570591 98.9% 961.32 662.59 720.48 516.84 75.46 38.25 811.96 618.66 56.85 3.00 2.51 0.24 -3.44 -3.50 Frag>80[3264,3265]
YJR072C NPA3 "Essential, conserved, cytoplasmic ATPase; phosphorylated by the Pcl1p-Pho85p kinase complex" Verified chr10:570960-572117 570960-572117 99.1% 345.12 232.70 258.84 244.03 97.61 98.48 288.91 251.43 98.05 1.07 1.02 0.41 -1.36 -0.81 Matched[3266]
YJR073C OPI3 "Phospholipid methyltransferase (methylene-fatty-acyl-phospholipid synthase), catalyzes the last two steps in phosphatidylcholine biosynthesis" Verified chr10:572308-572928 572308-572928 98.5% 518.19 464.24 568.86 554.15 998.77 836.94 491.21 561.50 917.86 1.81 2.28 3.80 0.71 0.45 Matched[3267]
YJR074W MOG1 "Conserved nuclear protein that interacts with GTP-Gsp1p, which is a Ran homolog of the Ras GTPase family, and stimulates nucleotide release, involved in nuclear protein import, nucleotide release is inhibited by Yrb1p" Verified chr10:573088-573744 573088-573744 98.3% 173.50 99.14 139.42 148.71 280.38 181.24 136.32 144.07 230.81 0.50 0.58 0.96 0.68 0.55 Covered/w/another[3268]
YJR075W HOC1 "Alpha-1,6-mannosyltransferase involved in cell wall mannan biosynthesis; subunit of a Golgi-localized complex that also contains Anp1p, Mnn9p, Mnn11p, and Mnn10p; identified as a suppressor of a cell lysis sensitive pkc1-371 allele" Verified chr10:573974-575164 573974-575164 98.8% 594.96 655.31 579.66 547.37 363.78 326.38 625.14 563.52 345.08 2.31 2.29 1.43 -0.71 -0.24 Covered/w/another[3268]
YJR076C CDC11 "Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM" Verified chr10:575347-576594 575347-576594 99.1% 392.22 318.63 396.27 380.90 341.27 313.78 355.43 388.58 327.53 1.31 1.58 1.36 -0.25 0.04 Covered/w/another[3268]
YJR077C MIR1 "Mitochondrial phosphate carrier, imports inorganic phosphate into mitochondria; functionally redundant with Pic2p but more abundant than Pic2p under normal conditions; phosphorylated" Verified chr10:577248-578183 577248-578183 98.2% 920.48 659.35 948.77 1142.44 855.20 786.65 789.92 1045.61 820.93 2.92 4.24 3.40 -0.35 -0.02 Frag>80[3269,3270,3271]
YJR078W BNA2 "Tryptophan 2,3-dioxygenase, required for biosynthesis of nicotinic acid from tryptophan via kynurenine pathway" Verified chr10:578853-580214 578853-580214 98.3% 22.41 25.39 30.62 23.15 34.36 35.85 23.90 26.89 35.10 0.09 0.11 0.15 0.38 0.82 Frag>80[3272]
YJR079W Putative protein of unknown function; mutation results in impaired mitochondrial respiration Uncharacterized chr10:580198-581232 580198-580340,581046-581232 99.1% 165.18 174.36 195.77 208.00 226.36 183.53 169.77 201.89 204.95 0.63 0.82 0.85 0.02 0.10 Covered/w/another[3273]
YJR080C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr10:580425-581609 580425-581609 99.1% 243.59 240.19 251.26 315.99 347.51 269.15 241.89 283.63 308.33 0.89 1.15 1.28 0.12 0.19 Matched[3273]
YJR082C EAF6 Subunit of the NuA4 acetyltransferase complex that acetylates histone H4 and NuA3 acetyltransferase complex that acetylates histone H3 Verified chr10:581907-582248 581907-582248 99.1% 297.86 274.27 221.18 262.47 271.32 174.00 286.07 241.83 222.66 1.06 0.98 0.92 -0.12 0.19 Covered/w/another[3273]
YJR083C ACF4 "Protein of unknown function, computational analysis of large-scale protein-protein interaction data suggests a possible role in actin cytoskeleton organization; potential Cdc28p substrate" Verified chr10:582601-583530 582601-583530 99.1% 93.30 115.00 103.06 95.47 118.25 73.77 104.15 99.27 96.01 0.38 0.40 0.40 -0.05 -0.23 Matched[3274]
YJR084W CSN12 "Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in adaptation to pheromone signaling" Verified chr10:583726-584997 583726-584997 98.6% 136.33 173.00 113.21 103.64 138.72 100.45 154.66 108.42 119.59 0.57 0.44 0.50 0.14 0.08 Matched[3275]
YJR085C "Putative protein of unknown function; GFP-fusion protein is induced in response to the DNA-damaging agent MMS; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr10:585113-585430 585113-585430 98.7% 914.13 1213.54 955.54 1000.13 2586.33 1567.09 1063.84 977.84 2076.71 3.93 3.97 8.60 1.09 0.27 Matched[3276]
YJR086W STE18 "G protein gamma subunit, forms a dimer with Ste4p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste4p to dampen signaling; C-terminus is palmitoylated and farnesylated, which are required for normal signaling" Verified chr10:586061-586393 586061-586393 99.1% 551.65 548.62 630.46 536.50 1576.16 800.20 550.14 583.48 1188.18 2.03 2.37 4.92 1.03 0.36 Frag<80[3277]
YJR087W "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; partially overlaps the verified gene STE18 and uncharacterized ORF YJR088C" Dubious chr10:586393-586743 586393-586743 99.5% 532.82 604.44 449.75 489.85 753.40 418.24 568.63 469.80 585.82 2.10 1.91 2.43 0.32 -0.43 Matched[3278]
YJR088C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum Uncharacterized chr10:586488-587366 586488-587366 99.4% 409.86 439.63 376.66 385.82 476.27 343.46 424.75 381.24 409.86 1.57 1.55 1.70 0.10 -0.04 Matched[3278]
YJR089W BIR1 "Essential chromosomal passenger protein involved in coordinating cell cycle events for proper chromosome segregation; C-terminal region binds Sli15p, and the middle region, upon phosphorylation, localizes Cbf2p to the spindle at anaphase" Verified chr10:587711-590575 587711-590575 98.7% 83.48 88.08 74.28 66.50 65.79 51.64 85.78 70.39 58.72 0.32 0.29 0.24 -0.26 0.21 Covered/w/another[3279]
YJR090C GRR1 "F-box protein component of the SCF ubiquitin-ligase complex; involved in carbon catabolite repression, glucose-dependent divalent cation transport, high-affinity glucose transport, morphogenesis, and sulfite detoxification" Verified chr10:590865-594320 590865-594320 98.9% 106.18 98.87 88.63 72.54 131.05 120.81 102.53 80.59 125.93 0.38 0.33 0.52 0.64 0.89 Covered/w/another[3279]
YJR091C JSN1 "Member of the Puf family of RNA-binding proteins, interacts with mRNAs encoding membrane-associated proteins; overexpression suppresses a tub2-150 mutation and causes increased sensitivity to benomyl in wild-type cells" Verified chr10:595054-598329 595054-598329 98.8% 145.46 150.71 163.68 157.82 210.94 360.72 148.09 160.75 285.83 0.55 0.65 1.18 0.83 1.78 Matched[3280]
YJR092W BUD4 Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding; potential Cdc28p substrate Verified chr10:598728-603074 598728-603074 98.5% 137.72 140.76 106.91 100.84 79.60 113.68 139.24 103.88 96.64 0.51 0.42 0.40 -0.10 0.45 Frag>80[3281]
YJR093C FIP1 "Subunit of cleavage polyadenylation factor (CPF), interacts directly with poly(A) polymerase (Pap1p) to regulate its activity" Verified chr10:603216-604199 603216-604199 98.9% 123.31 141.81 127.42 108.92 115.09 94.54 132.56 118.17 104.81 0.49 0.48 0.43 -0.17 0.35 Matched[3282]
YJR094C IME1 "Master regulator of meiosis that is active only during meiotic events, activates transcription of early meiotic genes through interaction with Ume6p, degraded by the 26S proteasome following phosphorylation by Ime2p" Verified chr10:604565-605647 604565-605647 99.0% 38.25 26.12 30.79 29.86 57.85 42.92 32.19 30.32 50.38 0.12 0.12 0.21 0.73 1.13 Matched[3283]
YJR094W-A RPL43B "Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein" Verified chr10:608301-608854 608301-608302,608578-608854 87.2% 6245.51 4375.96 5362.10 4318.44 1725.73 1171.03 5310.73 4840.27 1448.38 19.60 19.65 6.00 -1.74 -2.13 Matched[3286]
YJR095W SFC1 "Mitochondrial succinate-fumarate transporter, transports succinate into and fumarate out of the mitochondrion; required for ethanol and acetate utilization" Verified chr10:609769-610737 609769-610737 98.6% 5.23 6.28 3.14 0.00 14.66 19.89 5.76 1.57 17.27 0.02 0.01 0.07 3.46 2.36 Frag<80[3287]
YJR096W Putative xylose and arabinose reductase; member of the aldo-keto reductase (AKR) family; GFP-fusion protein is induced in response to the DNA-damaging agent MMS Verified chr10:611191-612039 611191-612039 98.5% 131.53 190.13 143.49 147.08 1750.59 1204.13 160.83 145.28 1477.36 0.59 0.59 6.12 3.35 2.97 Matched[3288]
YJR097W JJJ3 "Protein of unknown function, contains a J-domain, which is a region with homology to the E. coli DnaJ protein" Verified chr10:612409-612927 612409-612927 98.7% 56.60 35.13 25.37 11.71 3.90 1.95 45.86 18.54 2.93 0.17 0.08 0.01 -2.66 -1.90 Overlap[3289]
YJR098C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr10:613182-615149 613182-615149 99.2% 25.61 17.42 30.74 21.52 53.79 29.71 21.52 26.13 41.75 0.08 0.11 0.17 0.68 1.03 Matched[3289]
YJR099W YUH1 Ubiquitin C-terminal hydrolase that cleaves ubiquitin-protein fusions to generate monomeric ubiquitin; hydrolyzes the peptide bond at the C-terminus of ubiquitin; also the major processing enzyme for the ubiquitin-like protein Rub1p Verified chr10:615569-616279 615569-616279 98.7% 173.90 172.48 181.03 155.37 267.98 145.39 173.19 168.20 206.69 0.64 0.68 0.86 0.30 0.39 Matched[3290]
YJR100C "Putative protein of unknown function; appears related to murine NOR1, which is highly expressed in leukemogenic cell lines; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr10:616344-617327 616344-617327 99.2% 128.06 149.57 151.62 123.96 237.67 177.23 138.81 137.79 207.45 0.51 0.56 0.86 0.59 0.31 Matched[3291]
YJR101W RSM26 Mitochondrial ribosomal protein of the small subunit Verified chr10:618227-619027 618227-619027 98.7% 332.72 245.43 320.07 256.81 284.64 173.32 289.07 288.44 228.98 1.07 1.17 0.95 -0.33 -0.69 Matched[3292]
YJR102C VPS25 "Component of the ESCRT-II complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome" Verified chr10:619150-619758 619150-619758 99.3% 109.14 112.45 132.30 100.88 178.60 105.84 110.80 116.59 142.22 0.41 0.47 0.59 0.29 -0.13 Covered[3293]
YJR103W URA8 "Minor CTP synthase isozyme (see also URA7), catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis" Verified chr10:620747-622441 620747-622441 98.4% 220.62 287.16 232.01 285.96 422.65 579.12 253.89 258.99 500.89 0.94 1.05 2.08 0.95 1.30 Matched[3294]
YJR104C SOD1 Cytosolic superoxide dismutase; some mutations are analogous to those that cause ALS (amyotrophic lateral sclerosis) in humans Verified chr10:622542-623006 622542-623006 98.7% 4818.74 2765.71 5333.09 3552.49 11524.88 7379.59 3792.23 4442.79 9452.23 14.00 18.03 39.16 1.09 0.80 Matched[3295]
YJR105W ADO1 "Adenosine kinase, required for the utilization of S-adenosylmethionine (AdoMet); may be involved in recycling adenosine produced through the methyl cycle" Verified chr10:623573-624595 623573-624595 98.7% 1494.61 992.45 1384.67 1232.14 942.92 819.12 1243.53 1308.41 881.02 4.59 5.31 3.65 -0.57 -0.86 Matched[3297]
YJR106W ECM27 Non-essential protein of unknown function Verified chr10:624830-627007 624830-627007 99.0% 53.31 51.46 40.79 38.94 64.44 66.29 52.38 39.87 65.36 0.19 0.16 0.27 0.71 1.14 Covered[3298]
YJR107W Putative protein of unknown function; has sequence or structural similarity to lipases Uncharacterized chr10:627333-628319 627333-628319 98.7% 95.48 108.83 92.40 50.31 191.99 91.38 102.16 71.36 141.68 0.38 0.29 0.59 0.99 0.63 Frag<80[3299]
YJR108W ABM1 "Protein of unknown function, required for normal microtubule organization" Verified chr10:628706-629077 628706-629077 98.9% 19.03 16.31 21.75 16.31 43.50 24.47 17.67 19.03 33.99 0.07 0.08 0.14 0.84 0.63 Matched[3300]
YJR109C CPA2 "Large subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor" Verified chr10:629579-632935 629579-632935 99.0% 133.25 395.25 113.40 134.46 50.53 54.44 264.25 123.93 52.49 0.98 0.50 0.22 -1.24 -1.09 Matched[3301]
YJR110W YMR1 "Phosphatidylinositol 3-phosphate [PI(3)P] phosphatase, regulates the localization and levels of PI(3)P; involved in cytoplasm to vacuole (CVT) transport; has similarity to the conserved myotubularin dual specificity phosphatase family" Verified chr10:633609-635675 633609-635675 98.8% 92.58 96.99 91.11 88.17 102.87 62.21 94.79 89.64 82.54 0.35 0.36 0.34 -0.12 -0.05 Covered/w/another[3302]
YJR111C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondria Uncharacterized chr10:635849-636700 635849-636700 98.9% 96.09 138.79 73.55 53.38 55.75 26.10 117.44 63.46 40.93 0.43 0.26 0.17 -0.63 -0.11 Covered/w/another[3302]
YJR112W NNF1 Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; required for accurate chromosome segregation Verified chr10:637024-637629 637024-637629 98.0% 144.84 160.00 124.63 80.84 45.47 28.63 152.42 102.74 37.05 0.56 0.42 0.15 -1.47 -1.11 Matched[3303]
YJR112W-A Putative protein of unknown function; identified based on homology to Ashbya gossypii Uncharacterized chr10:637784-638162 637784-637803,637853-638162 98.3% 178.76 169.51 157.19 132.53 218.83 98.63 174.14 144.86 158.73 0.64 0.59 0.66 0.13 NaN Matched[3304]
YJR114W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF RSM7/YJR113C" Dubious chr10:638653-639045 638653-639045 98.8% 242.01 267.75 267.75 270.33 450.55 288.35 254.88 269.04 369.45 0.94 1.09 1.53 0.46 0.13 Frag>80[3305,3306]
YJR113C RSM7 "Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S7 ribosomal protein" Verified chr10:638226-638969 638226-638969 98.5% 313.87 327.51 349.35 292.03 620.91 371.18 320.69 320.69 496.05 1.18 1.30 2.06 0.63 0.48 Matched[3305]
YJR115W Putative protein of unknown function Uncharacterized chr10:639936-640445 639936-640445 94.2% 24.98 39.55 35.39 33.31 374.71 291.44 32.27 34.35 333.07 0.12 0.14 1.38 3.28 3.06 Matched[3308]
YJR116W Putative protein of unknown function Uncharacterized chr10:640819-641658 640819-641658 99.2% 112.86 136.88 94.85 82.85 144.08 128.47 124.87 88.85 136.27 0.46 0.36 0.56 0.62 0.44 Frag>80[3308,3309,3310]
YJR117W STE24 "Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation, C-terminal CAAX proteolysis and the first step of N-terminal proteolytic processing; contains multiple transmembrane spans" Verified chr10:642001-643362 642001-643362 99.3% 455.55 370.51 459.99 426.71 831.23 887.44 413.03 443.35 859.34 1.52 1.80 3.56 0.95 1.08 Matched[3311]
YJR118C ILM1 Protein of unknown function; may be involved in mitochondrial DNA maintenance; required for slowed DNA synthesis-induced filamentous growth Verified chr10:643484-644095 643484-644095 99.2% 536.88 507.24 418.31 423.25 423.25 182.80 522.06 420.78 303.03 1.93 1.71 1.26 -0.47 -0.61 Matched[3312]
YJR119C JHD2 JmjC domain family histone demethylase specific for H3-K4 (lysine at position 4 of the histone H3 protein); removes methyl groups specifically added by Set1p methyltransferase Verified chr10:644298-646484 644298-646484 99.2% 23.98 46.11 35.96 17.06 23.98 22.13 35.04 26.51 23.05 0.13 0.11 0.10 -0.20 0.34 Frag<80[3313,3314]
YJR120W "Protein of unknown function; essential for growth under anaerobic conditions; mutation causes decreased expression of ATP2, impaired respiration, defective sterol uptake, and altered levels/localization of ABC transporters Aus1p and Pdr11p" Verified chr10:647120-647470 647120-647470 98.7% 430.01 450.22 528.14 672.44 427.13 481.96 440.12 600.29 454.55 1.62 2.44 1.88 -0.40 2.13 Frag<80[3315]
YJR121W ATP2 "Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated" Verified chr10:647601-649136 647601-649136 98.7% 2593.67 2947.89 2928.76 3624.01 2734.83 2797.49 2770.78 3276.39 2766.16 10.23 13.30 11.46 -0.24 0.02 Matched[3316]
YJR122W CAF17 Mitochondrial protein that interacts with Ccr4p in the two-hybrid system; 3'-untranslated region contains a putative mRNA localization element common to genes encoding mitochondrial proteins Verified chr10:649770-651263 649770-651263 98.8% 90.12 121.29 106.38 88.77 108.42 95.54 105.71 97.57 101.98 0.39 0.40 0.42 0.06 0.16 Matched[3317]
YJR123W RPS5 "Protein component of the small (40S) ribosomal subunit, the least basic of the non-acidic ribosomal proteins; phosphorylated in vivo; essential for viability; has similarity to E. coli S7 and rat S5 ribosomal proteins" Verified chr10:651895-652572 651895-652572 98.7% 15925.32 13495.15 14930.54 13129.20 2757.28 2498.88 14710.23 14029.87 2628.08 54.30 56.95 10.89 -2.42 -3.86 Matched[3318]
YJR124C Putative protein of unknown function; expression induced under calcium shortage Uncharacterized chr10:652886-654232 652886-654232 99.0% 142.44 126.69 95.96 76.47 37.48 20.99 134.57 86.21 29.24 0.50 0.35 0.12 -1.56 -1.22 Matched[3319]
YJR125C ENT3 Protein containing an N-terminal epsin-like domain involved in clathrin recruitment and traffic between the Golgi and endosomes; associates with the clathrin adaptor Gga2p Verified chr10:654731-655957 654731-655957 99.1% 309.15 361.77 350.26 362.59 684.89 624.05 335.46 356.42 654.47 1.24 1.45 2.71 0.88 1.21 Frag>80[3320,3321]
YJR126C VPS70 Protein of unknown function involved in vacuolar protein sorting Verified chr10:656248-658683 656248-658683 99.1% 194.27 231.55 214.57 218.30 198.42 150.37 212.91 216.43 174.39 0.79 0.88 0.72 -0.31 -0.12 Matched[3322]
YJR128W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF RSF2" Dubious chr10:662915-663274 662915-663274 98.8% 16.88 14.06 22.50 5.63 11.25 16.88 15.47 14.06 14.06 0.06 0.06 0.06 0.00 1.56 Covered/w/another[3324]
YJR127C RSF2 "Zinc-finger protein involved in transcriptional control of both nuclear and mitochondrial genes, many of which specify products required for glycerol-based growth, respiration, and other functions" Verified chr10:658911-663053 658911-663053 98.7% 169.42 199.74 138.37 131.04 205.60 267.95 184.58 134.71 236.78 0.68 0.55 0.98 0.81 1.30 Frag>80[3323]
YJR129C Putative protein of unknown function; predicted S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr10:663994-665013 663994-665013 99.1% 73.20 59.35 43.52 36.60 17.81 30.67 66.28 40.06 24.24 0.24 0.16 0.10 -0.73 -0.91 Covered/w/another[3324]
YJR130C STR2 "Cystathionine gamma-synthase, converts cysteine into cystathionine" Verified chr10:665212-667131 665212-667131 99.2% 90.34 156.52 100.85 91.39 101.37 70.91 123.43 96.12 86.14 0.46 0.39 0.36 -0.16 -0.05 Matched[3325]
YJR131W MNS1 "Alpha-1,2-mannosidase involved in ER quality control; catalyzes the removal of one mannose residue from Man9GlcNAc to produce a single isomer of Man8GlcNAc in N-linked oligosaccharide biosynthesis; integral to ER membrane" Verified chr10:667638-669287 667638-669287 98.7% 90.28 89.66 91.50 90.28 111.77 104.40 89.97 90.89 108.09 0.33 0.37 0.45 0.25 0.67 Matched[3326]
YJR132W NMD5 "Karyopherin, a carrier protein involved in nuclear import of proteins; importin beta homolog" Verified chr10:669516-672662 669516-672662 98.9% 135.85 119.15 86.39 80.61 34.36 23.44 127.50 83.50 28.90 0.47 0.34 0.12 -1.53 -1.16 Matched[3327]
YJR133W XPT1 "Xanthine-guanine phosphoribosyl transferase, required for xanthine utilization and for optimal utilization of guanine" Verified chr10:672985-673614 672985-673614 98.5% 232.06 174.04 243.34 228.83 323.91 215.94 203.05 236.08 269.93 0.75 0.96 1.12 0.19 0.32 Covered/w/another[3328]
YJR134C SGM1 "Protein of unknown function, required for wild-type growth rate on galactose and mannose; localizes to COPI coated vesicles and the Golgi apparatus" Verified chr10:673723-675846 673723-675846 99.5% 248.51 248.04 245.20 228.63 199.76 177.51 248.27 236.91 188.63 0.92 0.96 0.78 -0.33 0.03 Covered/w/another[3328]
YJR135C MCM22 Protein involved in minichromosome maintenance; component of the kinetochore; binds to centromeric DNA in a Ctf19p-dependent manner Verified chr10:676053-676772 676053-676772 99.4% 60.10 53.11 19.57 48.92 50.32 34.94 56.61 34.24 42.63 0.21 0.14 0.18 0.32 -0.28 Covered/w/another[3328]
YJR135W-A TIM8 Mitochondrial intermembrane space protein mediating import and insertion of polytopic inner membrane proteins; homolog of human DDP1 (deafness dystonia peptide 1) which is mutated in the X-linked Mohr-Tranebjaerg syndrome Verified chr10:676965-677228 676965-677228 99.0% 673.58 566.42 631.48 639.13 715.68 329.13 620.00 635.31 522.40 2.29 2.58 2.16 -0.28 -0.88 Matched[3329]
YJR136C Putative protein of unknown function; may interact with mitochondrial ribosomal protein Rsm23p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr10:677435-678700 677435-678700 99.1% 58.96 71.71 56.57 61.35 49.40 31.87 65.34 58.96 40.64 0.24 0.24 0.17 -0.54 -0.33 Matched[3330]
YJR137C ECM17 "Sulfite reductase beta subunit, involved in amino acid biosynthesis, transcription repressed by methionine" Verified chr10:678951-683279 678951-683279 99.0% 70.22 89.81 70.92 59.95 64.85 77.45 80.01 65.43 71.15 0.30 0.27 0.29 0.12 0.98 Matched[3331]
YJR138W IML1 "Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the vacuolar membrane" Verified chr10:684561-689315 684561-689315 98.9% 72.54 77.86 57.22 60.20 51.69 62.12 75.20 58.71 56.91 0.28 0.24 0.24 -0.05 0.17 Matched[3332]
YJR139C HOM6 "Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase), dimeric enzyme that catalyzes the third step in the common pathway for methionine and threonine biosynthesis; enzyme has nucleotide-binding, dimerization and catalytic regions" Verified chr10:689439-690518 689439-690518 98.8% 1912.84 1644.80 1805.06 1757.26 1788.19 1318.65 1778.82 1781.16 1553.42 6.57 7.23 6.44 -0.20 -0.05 Frag>80[3333,3334]
YJR140W-A "Dubious open reading frame; completely overlaps the verified gene HIR3; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr10:690955-691104 690955-691104 98.9% 134.79 114.57 155.01 101.10 114.57 53.92 124.68 128.05 84.25 0.46 0.52 0.35 -0.60 NaN Covered/w/another[3335]
YJR140C HIR3 "Transcriptional corepressor involved in the cell cycle-regulated transcription of histone genes HTA1, HTB1, HHT1, and HHT2; involved in position-dependent gene silencing and nucleosome reassembly" Verified chr10:690744-695690 690744-695690 99.2% 57.47 51.15 40.35 36.48 28.94 28.73 54.31 38.41 28.84 0.20 0.16 0.12 -0.41 -0.26 Frag>80[3335]
YJR141W Putative protein of unknown function; may be involved in mRNA processing; YJR141W is an essential gene Uncharacterized chr10:695900-696943 695900-696943 98.8% 112.41 104.66 93.03 65.89 83.34 44.58 108.53 79.46 63.96 0.40 0.32 0.26 -0.31 -1.21 Matched[3336]
YJR142W Putative protein of unknown function; GST fusion protein is a Dbf2-Mob1 phosphoylation target in a proteome chip analysis; synthetic lethal with PH085 deletion Uncharacterized chr10:697135-698163 697135-698163 98.7% 191.93 257.87 218.50 199.80 300.20 189.96 224.90 209.15 245.08 0.83 0.85 1.02 0.23 -0.09 Matched[3337]
YJR143C PMT4 "Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; appears to form homodimers in vivo and does not complex with other Pmt proteins; target for new antifungals" Verified chr10:698320-700608 698320-700608 98.8% 679.16 576.58 650.86 625.66 189.24 167.14 627.87 638.26 178.19 2.32 2.59 0.74 -1.84 -1.00 Matched[3338]
YJR144W MGM101 "Protein involved in mitochondrial genome maintenance; component of the mitochondrial nucleoid, required for the repair of oxidative mtDNA damage" Verified chr10:700876-701685 700876-701685 98.3% 400.54 322.70 400.54 380.45 179.55 141.89 361.62 390.50 160.72 1.33 1.59 0.67 -1.28 -1.11 Matched[3339]
YJR145C RPS4A Protein component of the small (40S) ribosomal subunit; mutation affects 20S pre-rRNA processing; identical to Rps4Bp and has similarity to rat S4 ribosomal protein Verified chr10:702021-703062 702021-702792,703049-703062 24.6% 6947.23 5644.63 5877.23 5101.87 1405.99 1499.03 6295.93 5489.55 1452.51 23.24 22.28 6.02 -1.92 -2.53 Frag>80[3340,3341]
YJR146W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene HMS2" Dubious chr10:703879-704232 703879-704232 98.6% 71.62 68.75 88.80 48.70 123.18 88.80 70.18 68.75 105.99 0.26 0.28 0.44 0.62 -0.15 Covered/w/another[3342]
YJR147W HMS2 Protein with similarity to heat shock transcription factors; overexpression suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant Verified chr10:704190-705266 704190-705266 99.0% 231.68 216.67 172.59 94.74 69.41 52.53 224.18 133.66 60.97 0.83 0.54 0.25 -1.13 -1.26 Covered/w/another[3342]
YJR148W BAT2 "Cytosolic branched-chain amino acid aminotransferase, homolog of murine ECA39; highly expressed during stationary phase and repressed during logarithmic phase" Verified chr10:705738-706868 705738-706868 98.5% 842.56 1083.93 1053.43 1308.26 1143.16 1185.33 963.25 1180.84 1164.24 3.56 4.79 4.82 -0.02 0.24 Matched[3343]
YJR149W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr10:707154-708368 707154-708368 98.8% 67.50 66.67 64.17 55.84 103.34 50.00 67.09 60.00 76.67 0.25 0.24 0.32 0.35 0.93 Matched[3345]
YJR150C DAN1 "Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth" Verified chr10:708805-709701 708805-709701 97.1% 0.00 87.29 0.00 1.15 13.78 9.19 43.65 0.57 11.49 0.16 0.00 0.05 4.32 0.50
YJR151C DAN4 "Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth" Verified chr10:712249-715734 712249-715734 66.3% 39.35 58.37 38.48 27.24 16.86 30.70 48.86 32.86 23.78 0.18 0.13 0.10 -0.47 0.70 Frag<80[3346,3347,3348]
YJR151W-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr10:717574-717624 717574-717624 98.6% 19.88 0.00 0.00 0.00 19.88 0.00 9.94 0.00 9.94 0.04 0.00 0.04 Inf NaN
YJR152W DAL5 Allantoin permease; ureidosuccinate permease; expression is constitutive but sensitive to nitrogen catabolite repression Verified chr10:719660-721291 719660-721291 98.9% 50.21 78.10 48.35 41.53 51.45 29.13 64.15 44.94 40.29 0.24 0.18 0.17 -0.16 0.71 Covered[3349]
YJR153W PGU1 "Endo-polygalacturonase, pectolytic enzyme that hydrolyzes the alpha-1,4-glycosidic bonds in the rhamnogalacturonan chains in pectins" Verified chr10:722809-723894 722809-723894 98.7% 45.71 42.91 42.91 31.72 50.37 26.12 44.31 37.31 38.25 0.16 0.15 0.16 0.04 -0.25
YJR154W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr10:725778-726818 725778-726818 98.5% 24.39 38.05 11.71 12.68 7.80 12.68 31.22 12.19 10.24 0.12 0.05 0.04 -0.25 -0.24 Overlap[3350]
YJR155W AAD10 Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role Verified chr10:727399-728265 727399-728265 77.8% 74.14 131.97 54.86 37.07 93.41 47.45 103.05 45.97 70.43 0.38 0.19 0.29 0.62 0.88 Covered[3350]
YJR156C THI11 "Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP); member of a subtelomeric gene family including THI5, THI11, THI12, and THI13" Verified chr10:728568-729590 728568-729590 1.6% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.71
YJR157W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr10:730509-730871 730509-730871 2.5% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.29
YJR158W HXT16 "Protein of unknown function with similarity to hexose transporter family members, expression is repressed by high levels of glucose" Verified chr10:732434-734137 732434-734137 0.6% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.67
YJR159W SOR1 Sorbitol dehydrogenase; expression is induced in the presence of sorbitol Verified chr10:736038-737111 736038-737111 0.6% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.44
YJR160C MPH3 "Alpha-glucoside permease, transports maltose, maltotriose, alpha-methylglucoside, and turanose; identical to Mph2p; encoded in a subtelomeric position in a region likely to have undergone duplication" Verified chr10:738002-739810 738002-739810 1.1% 48.39 48.39 48.39 0.00 96.77 48.39 48.39 24.19 72.58 0.18 0.10 0.30 1.58 0.64
YJR161C COS5 "Protein of unknown function, member the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" Verified chr10:742842-743993 742842-743993 3.2% 27.21 0.00 27.21 81.63 0.00 0.00 13.61 54.42 0.00 0.05 0.22 0.00 -Inf 0.39
YJR162C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr10:744905-745255 744905-745255 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.68
YKL225W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr11:452-799 452-799 27.2% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN -0.35
YKL224C Putative protein of unknown function Uncharacterized chr11:1811-2182 1811-2182 2.1% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.91
YKL223W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr11:2390-2722 2390-2722 4.5% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.07
YKL222C "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; similar to transcriptional regulators from the zinc cluster (binuclear cluster) family; null mutant is sensitive to caffeine" Verified chr11:3504-5621 3504-5621 99.1% 44.30 57.64 40.49 42.39 45.25 40.01 50.97 41.44 42.63 0.19 0.17 0.18 0.04 0.38 Covered/w/another[3351]
YKL221W MCH2 "Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport" Verified chr11:6108-7529 6108-7529 99.1% 11.36 6.39 7.10 4.97 39.04 25.56 8.87 6.03 32.30 0.03 0.02 0.13 2.42 2.95 Covered/w/another[3351]
YKL220C FRE2 "Ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to uptake by transporters; expression induced by low iron levels but not by low copper levels" Verified chr11:9092-11227 9092-11227 96.3% 25.28 29.66 29.66 13.13 25.28 12.15 27.47 21.39 18.72 0.10 0.09 0.08 -0.19 0.63
YKL219W COS9 "Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" Verified chr11:14485-15708 14485-15708 89.9% 152.74 217.30 169.11 146.38 196.39 149.11 185.02 157.75 172.75 0.68 0.64 0.72 0.13 0.12 Matched[3353]
YKL218C SRY1 "3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required for survival in the presence of hydroxyaspartate" Verified chr11:17359-18339 17359-18339 99.0% 91.61 133.81 106.02 83.37 219.24 158.51 112.71 94.69 188.88 0.42 0.38 0.78 1.00 0.80 Matched[3355]
YKL217W JEN1 "Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is derepressed by transcriptional activator Cat8p during respiratory growth, and repressed in the presence of glucose, fructose, and mannose" Verified chr11:22234-24084 22234-24084 98.7% 23.54 34.48 29.56 29.56 65.14 61.85 29.01 29.56 63.49 0.11 0.12 0.26 1.10 0.32 Covered[3356]
YKL216W URA1 "Dihydroorotate dehydrogenase, catalyzes the fourth enzymatic step in the de novo biosynthesis of pyrimidines, converting dihydroorotic acid into orotic acid" Verified chr11:25216-26160 25216-26160 98.8% 3562.62 2521.47 3043.11 3121.31 625.55 516.29 3042.04 3082.21 570.92 11.23 12.51 2.37 -2.43 -2.11 Frag>80[3357,3358]
YKL215C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr11:26828-30688 26828-30688 99.1% 64.84 67.45 57.52 55.16 69.54 77.12 66.14 56.34 73.33 0.24 0.23 0.30 0.38 0.91 Frag>80[3359,3360,3361]
YKL214C YRA2 "Member of the REF (RNA and export factor binding proteins) family; when overexpressed, can substitute for the function of Yra1p in export of poly(A)+ mRNA from the nucleus" Verified chr11:31083-31694 31083-31694 99.1% 234.11 227.52 222.57 214.33 179.71 95.62 230.82 218.45 137.67 0.85 0.89 0.57 -0.67 -0.71 Matched[3362]
YKL213C DOA1 "WD repeat protein required for ubiquitin-mediated protein degradation, forms complex with Cdc48p, plays a role in controlling cellular ubiquitin concentration; also promotes efficient NHEJ in postdiauxic/stationary phase" Verified chr11:31961-34108 31961-34108 99.2% 174.62 186.82 180.72 185.88 305.11 240.33 180.72 183.30 272.72 0.67 0.74 1.13 0.57 1.15 Matched[3363]
YKL212W SAC1 "Lipid phosphoinositide phosphatase of the ER and Golgi, involved in protein trafficking and secretion" Verified chr11:34544-36415 34544-36415 98.7% 694.37 674.35 616.44 557.99 334.47 405.37 684.36 587.21 369.92 2.53 2.38 1.53 -0.67 -0.16 Matched[3364]
YKL211C TRP3 "Bifunctional enzyme exhibiting both indole-3-glycerol-phosphate synthase and anthranilate synthase activities, forms multifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp2p" Verified chr11:36700-38154 36700-38154 98.9% 300.24 423.26 298.16 301.63 217.54 137.61 361.75 299.90 177.57 1.34 1.22 0.74 -0.76 -0.53 Matched[3365]
YKL210W UBA1 "Ubiquitin activating enzyme (E1), involved in ubiquitin-mediated protein degradation and essential for viability" Verified chr11:39164-42238 39164-42238 98.8% 700.62 574.20 615.02 627.86 606.79 665.72 637.41 621.44 636.26 2.35 2.52 2.64 0.03 0.29 Matched[3367]
YKL209C STE6 "Plasma membrane ATP-binding cassette (ABC) transporter required for the export of a-factor, catalyzes ATP hydrolysis coupled to a-factor transport; contains 12 transmembrane domains and two ATP binding domains; expressed only in MATa cells" Verified chr11:42424-46296 42424-46296 99.2% 437.95 519.45 424.94 368.95 179.66 146.07 478.70 396.94 162.87 1.77 1.61 0.67 -1.29 -0.82 Frag>80[3368,3369]
YKL208W CBT1 "Protein involved in 5' end processing of mitochondrial COB, 15S_rRNA, and RPM1 transcripts; may also have a role in 3' end processing of the COB pre-mRNA; displays genetic interaction with cell cycle-regulated kinase Dbf2p" Verified chr11:47158-47973 47158-47973 98.6% 72.06 80.76 60.88 63.37 104.37 47.21 76.41 62.12 75.79 0.28 0.25 0.31 0.29 0.27 Matched[3370]
YKL207W Putative protein of unknown function; non-essential gene Uncharacterized chr11:48195-48956 48195-48956 98.6% 798.71 847.97 772.09 712.19 593.71 441.95 823.34 742.14 517.83 3.04 3.01 2.15 -0.52 -0.53 Matched[3371]
YKL206C ADD66 Protein involved in 20S proteasome assembly; forms a heterodimer with Pba1p that binds to proteasome precursors; similar to human PAC2 constituent of the PAC1-PAC2 complex involved in proteasome assembly Verified chr11:49007-49810 49007-49810 99.1% 165.75 169.52 154.45 144.40 251.14 165.75 167.63 149.43 208.44 0.62 0.61 0.86 0.48 0.17 Matched[3372]
YKL205W LOS1 Nuclear pore protein involved in nuclear export of pre-tRNA Verified chr11:50052-53354 50052-53354 99.2% 144.07 109.88 99.20 86.99 43.34 41.82 126.98 93.10 42.58 0.47 0.38 0.18 -1.13 -0.59 Matched[3373]
YKL204W EAP1 "eIF4E-associated protein, binds eIF4E and inhibits cap-dependent translation, also functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade" Verified chr11:53705-55603 53705-55603 98.7% 210.30 203.89 201.22 214.03 210.83 258.33 207.09 207.63 234.58 0.76 0.84 0.97 0.18 0.81 Matched[3374]
YKL203C TOR2 "PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth in response to nutrients and TORC2, a complex that regulates cell-cycle dependent polarization of the actin cytoskeleton; involved in meiosis" Verified chr11:55936-63360 55936-63360 99.1% 51.77 49.33 49.19 44.57 30.17 39.68 50.55 46.88 34.92 0.19 0.19 0.14 -0.42 -0.09 Frag<80[3375]
YKL202W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr11:63822-64403 63822-64403 77.6% 150.55 201.48 201.48 183.76 469.37 325.46 176.01 192.62 397.42 0.65 0.78 1.65 1.04 0.56 Covered/w/another[3376]
YKL201C MNN4 "Putative positive regulator of mannosylphosphate transferase (Mnn6p), involved in mannosylphosphorylation of N-linked oligosaccharides; expression increases in late-logarithmic and stationary growth phases" Verified chr11:63931-67467 63931-67467 95.4% 88.30 125.94 112.01 93.34 164.46 155.57 107.12 102.67 160.01 0.40 0.42 0.66 0.64 1.05 Covered/w/another[3376]
YKL198C PTK1 Putative serine/threonine protein kinase that regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein Verified chr11:68274-70223 68274-70223 98.0% 121.95 171.14 127.70 72.75 75.89 64.38 146.55 100.23 70.13 0.54 0.41 0.29 -0.52 0.59 Covered/w/another[3376]
YKL197C PEX1 AAA-peroxin that heterodimerizes with AAA-peroxin Pex6p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol; induced by oleic acid and upregulated during anaerobiosis Verified chr11:70739-73870 70739-73870 99.2% 49.23 56.95 45.36 39.25 40.86 52.44 53.09 42.31 46.65 0.20 0.17 0.19 0.14 0.66 Covered/w/another[3376]
YKL196C YKT6 "Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in trafficking to and within the Golgi, endocytic trafficking to the vacuole, and vacuolar fusion; membrane localization due to prenylation at the carboxy-terminus" Verified chr11:74937-75539 74937-75539 99.4% 781.14 650.95 749.43 677.65 1043.19 619.24 716.04 713.54 831.21 2.64 2.90 3.44 0.22 -0.35 Frag>80[3378,3379]
YKL195W MIA40 Essential protein of the mitochondrial intermembrane space (IMS); promotes retention of newly imported proteins; may do so by stabilizing client protein folding as part of a disulfide relay system or transferring metal to client proteins Verified chr11:75826-77037 75826-77037 98.2% 599.79 597.27 724.12 740.92 1433.11 851.80 598.53 732.52 1142.46 2.21 2.97 4.73 0.64 0.65 Matched[3380]
YKL194C MST1 Mitochondrial threonyl-tRNA synthetase Verified chr11:77263-78651 77263-78651 99.0% 111.98 117.80 125.07 121.44 157.07 117.80 114.89 123.25 137.43 0.42 0.50 0.57 0.16 0.31 Matched[3381]
YKL193C SDS22 "Conserved nuclear regulatory subunit of Glc7p type 1 protein serine-threonine phosphatase (PP1), functions positively with Glc7p to promote dephosphorylation of nuclear substrates required for chromosome transmission during mitosis" Verified chr11:78871-79887 78871-79887 99.1% 235.20 281.84 308.63 291.76 659.94 558.72 258.52 300.20 609.33 0.95 1.22 2.52 1.02 1.29 Frag>80[3382,3383,3384]
YKL192C ACP1 "Mitochondrial matrix acyl carrier protein, involved in biosynthesis of octanoate, which is a precursor to lipoic acid; activated by phosphopantetheinylation catalyzed by Ppt2p" Verified chr11:80165-80542 80165-80542 98.6% 1159.21 952.59 1178.00 1078.71 1867.62 1279.96 1055.90 1128.35 1573.79 3.90 4.58 6.52 0.48 0.51 Frag>80[3384,3385]
YKL191W DPH2 "Protein required, along with Dph1p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph1p and Kti11p" Verified chr11:81040-82644 81040-82644 98.5% 169.50 104.99 131.56 84.75 34.79 16.44 137.25 108.15 25.62 0.51 0.44 0.11 -2.08 -1.15 Matched[3386]
YKL190W CNB1 "Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulated type 2B protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is encoded by CNA1 and/or CMP1" Verified chr11:82952-83555 82952-83003,83080-83555 98.4% 573.54 585.08 550.44 517.72 658.22 448.44 579.31 534.08 553.33 2.14 2.17 2.29 0.05 0.23 Matched[3387]
YKL189W HYM1 "Component of the RAM signaling network that is involved in regulation of Ace2p activity and cellular morphogenesis, interacts with Kic1p and Sog2p, localizes to sites of polarized growth during budding and during the mating response" Verified chr11:84709-85908 84709-85908 99.1% 102.60 130.36 117.74 116.06 173.25 118.58 116.48 116.90 145.92 0.43 0.47 0.60 0.32 0.67 Matched[3388]
YKL188C PXA2 "Subunit of a heterodimeric peroxisomal ATP-binding cassette transporter complex (Pxa1p-Pxa2p), required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter and ALD-related proteins" Verified chr11:86230-88791 86230-88791 99.2% 22.03 40.92 29.11 33.05 60.59 43.28 31.47 31.08 51.93 0.12 0.13 0.22 0.74 1.28 Frag>80[3389]
YKL187C "Putative protein of unknown function; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies" Uncharacterized chr11:89289-91541 89289-91541 98.6% 36.90 43.65 33.30 34.20 94.51 78.75 40.28 33.75 86.63 0.15 0.14 0.36 1.36 1.66 Covered[3390]
YKL186C MTR2 "mRNA transport regulator, essential nuclear protein; Mex67p and Mtr2p form a mRNA export complex which binds to RNA" Verified chr11:92749-93471 92749-93316,93470-93471 99.0% 347.34 398.73 375.69 336.71 382.78 219.74 373.03 356.20 301.26 1.38 1.45 1.25 -0.24 -0.34 Frag>80[3391,3392]
YKL185W ASH1 "Zinc-finger inhibitor of HO transcription; mRNA is localized and translated in the distal tip of anaphase cells, resulting in accumulation of Ash1p in daughter cell nuclei and inhibition of HO expression; potential Cdc28p substrate" Verified chr11:94504-96270 94504-96270 99.0% 317.96 399.74 353.42 260.78 284.80 228.75 358.85 307.10 256.77 1.32 1.25 1.06 -0.26 0.36 Matched[3393]
YKL184W SPE1 "Ornithine decarboxylase, catalyzes the first step in polyamine biosynthesis; degraded in a proteasome-dependent manner in the presence of excess polyamines" Verified chr11:96762-98162 96762-98162 98.9% 350.79 321.92 347.18 311.81 202.82 144.36 336.35 329.49 173.59 1.24 1.34 0.72 -0.92 -0.60 Matched[3394]
YKL183C-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr11:98400-98612 98400-98612 99.2% 70.99 52.06 37.86 47.33 37.86 42.60 61.53 42.60 40.23 0.23 0.17 0.17 -0.08 NaN Matched[3395]
YKL183W LOT5 Protein of unknown function; gene expression increases in cultures shifted to a lower temperature Verified chr11:98726-99646 98726-99646 98.3% 189.96 189.96 196.59 168.98 94.98 98.29 189.96 182.78 96.64 0.70 0.74 0.40 -0.92 -0.31 Frag>80[3395,3396]
YKL182W FAS1 "Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities" Verified chr11:100676-106831 100676-106831 98.9% 826.07 1307.82 731.82 690.61 141.54 138.42 1066.94 711.21 139.98 3.94 2.89 0.58 -2.35 -1.81 Frag>80[3397,3398,3399]
YKL181W PRS1 "5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes" Verified chr11:107321-108604 107321-108604 98.7% 913.76 637.58 798.55 677.03 214.63 114.42 775.67 737.79 164.52 2.86 2.99 0.68 -2.16 -1.85 Matched[3400]
YKL180W RPL17A "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Bp and has similarity to E. coli L22 and rat L17 ribosomal proteins; copurifies with the Dam1 complex (aka DASH complex)" Verified chr11:109274-110134 109274-109582,109889-110134 65.2% 6094.71 5223.64 5301.07 4349.81 1172.49 702.39 5659.18 4825.44 937.44 20.89 19.59 3.88 -2.36 -2.38 Frag>80[3401,3402]
YKL179C COY1 Golgi membrane protein with similarity to mammalian CASP; genetic interactions with GOS1 (encoding a Golgi snare protein) suggest a role in Golgi function Verified chr11:110469-112508 110469-112508 99.5% 199.09 203.53 203.53 188.25 262.66 193.67 201.31 195.89 228.17 0.74 0.80 0.95 0.22 0.42 Matched[3403]
YKL177W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene STE3" Dubious chr11:114361-114699 114361-114699 99.4% 0.00 0.00 0.00 2.97 11.87 5.94 0.00 1.48 8.90 0.00 0.01 0.04 2.58 0.34
YKL178C STE3 "Receptor for a factor receptor, transcribed in alpha cells and required for mating by alpha cells, couples to MAP kinase cascade to mediate pheromone response; ligand bound receptors are endocytosed and recycled to the plasma membrane; GPCR" Verified chr11:113220-114632 113220-114632 99.0% 7.86 2.14 3.57 5.72 16.44 8.58 5.00 4.64 12.51 0.02 0.02 0.05 1.43 1.21 Frag<80[3404,3405]
YKL176C LST4 Protein possibly involved in a post-Golgi secretory pathway; required for the transport of nitrogen-regulated amino acid permease Gap1p from the Golgi to the cell surface Verified chr11:115505-117991 115505-117991 99.0% 238.79 206.30 190.47 154.73 86.50 56.86 222.55 172.60 71.68 0.82 0.70 0.30 -1.27 -0.89 Matched[3406]
YKL175W ZRT3 "Vacuolar membrane zinc transporter, transports zinc from storage in the vacuole to the cytoplasm when needed; transcription is induced under conditions of zinc deficiency" Verified chr11:118798-120309 118798-120309 99.0% 316.10 263.30 289.37 280.68 177.09 141.68 289.70 285.02 159.39 1.07 1.16 0.66 -0.84 -0.34 Matched[3407]
YKL174C TPO5 Protein involved in excretion of putrescine and spermidine; putative polyamine transporter in the Golgi or post-Golgi vesicles Verified chr11:120385-122241 120385-122241 99.0% 138.23 130.61 120.81 102.31 97.96 82.18 134.42 111.56 90.07 0.50 0.45 0.37 -0.31 -0.08 Matched[3408]
YKL173W SNU114 GTPase component of U5 snRNP involved in mRNA splicing via spliceosome; binds directly to U5 snRNA; proposed to be involved in conformational changes of the spliceosome; similarity to ribosomal translocation factor EF-2 Verified chr11:122522-125548 122522-125548 98.8% 87.65 84.30 72.60 63.90 35.80 43.82 85.98 68.25 39.81 0.32 0.28 0.16 -0.78 -0.29 Matched[3409]
YKL172W EBP2 "Essential protein required for the maturation of 25S rRNA and 60S ribosomal subunit assembly, localizes to the nucleolus; constituent of 66S pre-ribosomal particles" Verified chr11:125764-127047 125764-127047 97.3% 742.07 417.06 518.73 415.46 58.44 34.42 579.57 467.10 46.43 2.14 1.90 0.19 -3.33 -3.39 Frag>80[3410,3411]
YKL171W Putative protein of unknown function; predicted protein kinase; implicated in proteasome function; epitope-tagged protein localizes to the cytoplasm Uncharacterized chr11:127480-130266 127480-130266 98.8% 68.28 58.11 65.37 59.56 111.86 108.95 63.19 62.47 110.41 0.23 0.25 0.46 0.82 1.62 Matched[3412]
YKL170W MRPL38 Mitochondrial ribosomal protein of the large subunit; appears as two protein spots (YmL34 and YmL38) on two-dimensional SDS gels Verified chr11:130639-131055 130639-131055 98.5% 394.52 284.93 438.36 387.21 426.18 250.84 339.73 412.79 338.51 1.25 1.68 1.40 -0.29 -0.37 Covered/w/another[3413]
YKL169C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene MRPL38" Dubious chr11:130690-131073 130690-131073 98.5% 412.56 293.55 483.97 394.05 439.01 259.17 353.06 439.01 349.09 1.30 1.78 1.45 -0.33 -0.45 Covered/w/another[3413]
YKL168C KKQ8 Putative serine/threonine protein kinase with unknown cellular role Verified chr11:131293-133467 131293-133467 99.0% 73.35 98.42 68.71 77.06 178.27 133.24 85.88 72.88 155.75 0.32 0.30 0.65 1.10 0.94 Covered/w/another[3413]
YKL167C MRP49 "Mitochondrial ribosomal protein of the large subunit, not essential for mitochondrial translation" Verified chr11:133726-134139 133726-134139 99.3% 245.67 282.15 330.80 321.07 569.17 355.12 263.91 325.93 462.15 0.97 1.32 1.91 0.50 0.49 Covered/w/another[3413]
YKL166C TPK3 cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk1p and Tpk2p Verified chr11:134514-135710 134514-135710 99.2% 207.18 157.49 157.49 113.70 74.11 53.90 182.33 135.59 64.01 0.67 0.55 0.27 -1.08 -1.38 Covered/w/another[3413]
YKL165C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr11:135795-136028 135795-136028 98.8% 17.31 21.64 34.62 30.29 12.98 8.65 19.47 32.46 10.82 0.07 0.13 0.04 -1.58 -1.25 Covered/w/another[3413]
YKL165C MCD4 Protein involved in glycosylphosphatidylinositol (GPI) anchor synthesis; multimembrane-spanning protein that localizes to the endoplasmic reticulum; highly conserved among eukaryotes Verified chr11:137937-140696 137937-140696 99.0% 185.57 160.31 168.73 133.23 118.22 86.38 172.94 150.98 102.30 0.64 0.61 0.42 -0.56 -0.45 Covered/w/another[3413]
YKL164C PIR1 "O-glycosylated protein required for cell wall stability; attached to the cell wall via beta-1,3-glucan; mediates mitochondrial translocation of Apn1p; expression regulated by the cell integrity pathway and by Swi5p during the cell cycle" Verified chr11:141799-142824 141799-142824 59.6% 1928.89 1701.68 2072.74 1373.11 3027.38 1418.88 1815.28 1722.93 2223.13 6.70 6.99 9.21 0.37 0.37 Frag>80[3414,3415]
YKL163W PIR3 "O-glycosylated covalently-bound cell wall protein required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway" Verified chr11:144406-145383 144406-145383 69.8% 67.34 70.27 70.27 32.21 231.30 165.43 68.81 51.24 198.37 0.25 0.21 0.82 1.95 1.93 Frag<80[3417,3418]
YKL162C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr11:145927-146079 145927-146079 98.4% 6.64 6.64 26.57 0.00 46.50 39.86 6.64 13.29 43.18 0.02 0.05 0.18 1.70 0.73 Matched[3418]
YKL162C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion Uncharacterized chr11:147635-148843 147635-148843 99.2% 35.04 23.36 49.22 46.71 82.58 58.39 29.20 47.96 70.49 0.11 0.19 0.29 0.56 1.49 Matched[3419]
YKL161C Protein kinase implicated in the Slt2p mitogen-activated (MAP) kinase signaling pathway; associates with Rlm1p Verified chr11:149391-150692 149391-150692 99.2% 64.28 65.83 50.34 33.30 78.99 42.59 65.05 41.82 60.79 0.24 0.17 0.25 0.54 0.53 Covered[3420]
YKL160W ELF1 Transcription elongation factor that contains a conserved zinc finger domain; implicated in the maintenance of proper chromatin structure in actively transcribed regions; deletion inhibits Brome mosaic virus (BMV) gene expression Verified chr11:153274-153711 153274-153711 98.3% 694.27 436.53 745.36 571.21 866.10 527.09 565.40 658.28 696.59 2.09 2.67 2.89 0.08 -0.01 Matched[3421]
YKL159C RCN1 Protein involved in calcineurin regulation during calcium signaling; has similarity to H. sapiens DSCR1 which is found in the Down Syndrome candidate region Verified chr11:153821-154456 153821-154456 99.2% 109.36 104.60 79.24 90.34 141.06 115.70 106.98 84.79 128.38 0.39 0.34 0.53 0.60 0.50 Matched[3422]
YKL157W APE2 "Zinc-dependent metallopeptidase yscII, may have a role in obtaining leucine from dipeptide substrates; sequence coordinates have changed since RT-PCR analysis showed that the adjacent ORF YKL158W comprises the 5' exon of APE2/YKL157W" Verified chr11:154996-158186 154996-155276,155660-158186 98.4% 423.34 499.32 450.11 476.16 386.79 431.66 461.33 463.14 409.23 1.70 1.88 1.70 -0.18 0.58 Matched[3423]
YKL156W RPS27A Protein component of the small (40S) ribosomal subunit; nearly identical to Rps27Bp and has similarity to rat S27 ribosomal protein Verified chr11:158619-159217 158619-158621,158972-159217 98.1% 4717.28 4000.68 3951.54 3144.86 880.40 245.69 4358.98 3548.20 563.04 16.09 14.40 2.33 -2.66 -3.81 Matched[3424]
YKL156C-A "Dubious open reading frame unlikely to encode a protein; completely overlaps the verified gene RPS27A; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr11:158980-159096 158980-159096 98.9% 4433.56 3638.46 3975.51 3310.05 795.10 241.99 4036.01 3642.78 518.55 14.90 14.79 2.15 -2.81 NaN Matched[3424]
YKL155C RSM22 Mitochondrial ribosomal protein of the small subunit Verified chr11:159461-161347 159461-161347 99.2% 110.57 113.25 118.05 125.53 80.13 56.09 111.91 121.79 68.11 0.41 0.49 0.28 -0.84 -0.31 Matched[3425]
YKL154W SRP102 Signal recognition particle (SRP) receptor beta subunit; involved in SRP-dependent protein targeting; anchors Srp101p to the ER membrane Verified chr11:161606-162340 161606-162340 98.7% 310.20 250.92 256.43 248.16 227.48 125.46 280.56 252.30 176.47 1.04 1.02 0.73 -0.52 -1.03 Frag>80[3426,3427]
YKL153W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; transcription of both YLK153W and the overlapping essential gene GPM1 is reduced in the gcr1 null mutant" Dubious chr11:163605-164114 163605-164114 98.7% 46712.90 55976.83 44077.13 43459.41 49007.04 38515.60 51344.87 43768.27 43761.32 189.54 177.66 181.32 -0.00 -0.02 Matched[3429]
YKL152C GPM1 "Tetrameric phosphoglycerate mutase, mediates the conversion of 3-phosphoglycerate to 2-phosphoglycerate during glycolysis and the reverse reaction during gluconeogenesis" Verified chr11:163647-164390 163647-164390 98.8% 42955.67 50870.43 41378.98 40727.36 43717.50 36397.23 46913.05 41053.17 40057.36 173.18 166.64 165.97 -0.04 -1.09 Matched[3429]
YKL151C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr11:164922-165935 164922-165935 99.2% 210.78 417.58 245.58 275.40 3173.62 2455.78 314.18 260.49 2814.70 1.16 1.06 11.66 3.43 3.28 Matched[3431]
YKL150W MCR1 "Mitochondrial NADH-cytochrome b5 reductase, involved in ergosterol biosynthesis" Verified chr11:166404-167457 166404-166405,166493-167457 98.8% 518.19 814.45 735.93 829.10 3283.96 1849.78 666.32 782.52 2566.87 2.46 3.18 10.64 1.71 1.41 Matched[3432]
YKL149C DBR1 "RNA lariat debranching enzyme, involved in intron turnover; required for efficient Ty1 transposition" Verified chr11:167617-168834 167617-168834 99.3% 100.09 80.23 65.35 56.25 71.14 42.19 90.16 60.80 56.66 0.33 0.25 0.23 -0.10 -0.03 Frag>80[3433,3434]
YKL148C SDH1 "Flavoprotein subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone" Verified chr11:169212-171134 169212-171134 98.8% 218.47 281.12 361.14 491.70 435.89 553.29 249.80 426.42 494.59 0.92 1.73 2.05 0.21 0.72 Matched[3435]
YKL146W AVT3 "Vacuolar transporter, exports large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters" Verified chr11:171788-173866 171788-173866 98.6% 108.73 111.17 126.77 119.46 135.06 124.82 109.95 123.12 129.94 0.41 0.50 0.54 0.08 0.44 Matched[3436]
YKL147C "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; partially overlaps the verified gene AVT3" Dubious chr11:171556-172173 171556-172173 98.0% 44.60 44.60 66.08 56.17 56.17 62.78 44.60 61.12 59.47 0.16 0.25 0.25 -0.04 0.03 Covered/w/another[3436]
YKL145W RPT1 One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for optimal CDC20 transcription; interacts with Rpn12p and the E3 ubiquitin-protein ligase Ubr1p Verified chr11:174218-175621 174218-175621 98.5% 790.94 559.59 761.30 675.26 947.83 725.15 675.26 718.28 836.49 2.49 2.92 3.47 0.22 0.17 Matched[3437]
YKL145W-A "Dubious open reading frame, unlikely to encode a protein; completely overlaps the verified essential gene RPT1; identified by expression profiling and mass spectrometry" Dubious chr11:174963-175055 174963-175055 98.6% 752.39 545.21 774.19 806.91 806.91 577.92 648.80 790.55 692.41 2.40 3.21 2.87 -0.19 NaN Covered/w/another[3437]
YKL144C RPC25 RNA polymerase III subunit C25 Verified chr11:175848-176486 175848-176486 99.3% 189.21 126.14 108.80 88.30 34.69 17.34 157.68 98.55 26.02 0.58 0.40 0.11 -1.92 -1.33 Matched[3438]
YKL143W LTV1 "Component of the GSE complex, which is required for proper sorting of amino acid permease Gap1p; required for ribosomal small subunit export from nucleus; required for growth at low temperature" Verified chr11:176786-178177 176786-178177 98.2% 245.73 105.31 146.27 103.85 14.63 2.93 175.52 125.06 8.78 0.65 0.51 0.04 -3.83 -4.27 Matched[3439]
YKL142W MRP8 "Putative mitochondrial ribosomal protein, has similarity to E. coli ribosomal protein S2" Verified chr11:178520-179179 178520-179179 98.5% 836.39 990.13 960.92 902.50 3434.72 2423.06 913.26 931.71 2928.89 3.37 3.78 12.14 1.65 1.44 Matched[3440]
YKL141W SDH3 "Cytochrome b subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone" Verified chr11:179672-180268 179672-180268 98.9% 653.45 809.20 841.36 1080.06 1460.96 1008.96 731.33 960.71 1234.96 2.70 3.90 5.12 0.36 0.29 Matched[3441]
YKL140W TGL1 "Steryl ester hydrolase, one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes" Verified chr11:180784-182430 180784-182430 99.1% 185.12 312.01 277.07 266.65 370.24 245.80 248.56 271.86 308.02 0.92 1.10 1.28 0.18 0.63 Matched[3442]
YKL139W CTK1 "Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates the C-terminal repeated domain of the RNA polymerase II large subunit (Rpo21p) to affect both transcription and pre-mRNA 3' end processing" Verified chr11:182963-184549 182963-184549 98.2% 98.84 103.98 86.65 66.11 69.32 47.50 101.41 76.38 58.41 0.37 0.31 0.24 -0.39 -0.21 Matched[3443]
YKL138C-A HSK3 "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis" Verified chr11:184808-185017 184808-185017 99.8% 262.43 257.65 248.11 157.46 429.42 209.94 260.04 202.78 319.68 0.96 0.82 1.32 0.66 NaN Covered/w/another[3444]
YKL138C MRPL31 Mitochondrial ribosomal protein of the large subunit Verified chr11:185291-185686 185291-185686 99.3% 544.47 501.22 623.34 531.75 651.33 491.04 522.85 577.55 571.19 1.93 2.34 2.37 -0.02 0.01 Covered/w/another[3444]
YKL137W Putative protein of unknown function; mutation results in growth defect on a non-fermentable (respiratory) carbon source Uncharacterized chr11:185962-186297 185962-186297 98.6% 467.75 419.46 407.39 392.30 941.53 510.00 443.61 399.85 725.76 1.64 1.62 3.01 0.86 0.00 Covered/w/another[3444]
YKL136W Hypothetical protein Dubious chr11:186421-186819 186421-186819 99.6% 203.90 309.63 236.63 208.94 357.46 153.56 256.77 222.78 255.51 0.95 0.90 1.06 0.20 0.35
YKL135C APL2 "Beta-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting" Verified chr11:186465-188645 186465-188645 99.3% 164.92 187.55 156.60 156.14 159.37 128.88 176.23 156.37 144.13 0.65 0.63 0.60 -0.12 0.03 Frag>80[3445]
YKL134C Oct-01 "Mitochondrial intermediate peptidase, cleaves N-terminal residues of a subset of proteins upon import, after their cleavage by mitochondrial processing peptidase (Mas1p-Mas2p); may contribute to mitochondrial iron homeostasis" Verified chr11:189129-191441 189129-191441 99.3% 55.31 44.86 50.95 42.68 51.82 33.97 50.08 46.82 42.90 0.18 0.19 0.18 -0.13 0.27 Matched[3446]
YKL133C Putative protein of unknown function Uncharacterized chr11:191678-193069 191678-193069 99.3% 54.99 52.82 56.44 57.89 222.87 113.61 53.91 57.17 168.24 0.20 0.23 0.70 1.56 0.78 Matched[3447]
YKL131W "Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr11:194477-194998 194477-194998 99.1% 29.01 42.54 25.14 23.21 21.27 19.34 35.77 24.17 20.30 0.13 0.10 0.08 -0.25 0.04 Covered/w/another[3448]
YKL132C RMA1 "Putative dihydrofolate synthetase; has similarity to Fol3p and to E. coli folylpolyglutamate synthetase/dihydrofolate synthetase; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr11:193573-194865 193573-194865 99.1% 38.23 53.83 39.79 29.64 34.32 18.72 46.03 34.71 26.52 0.17 0.14 0.11 -0.39 0.03 Matched[3448]
YKL130C SHE2 RNA-binding protein that binds specific mRNAs and interacts with She3p; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud Verified chr11:195287-196027 195287-196027 99.2% 200.02 208.19 182.33 151.04 214.99 126.54 204.10 166.69 170.77 0.75 0.68 0.71 0.03 0.11 Frag>80[3449,3450,3451]
YKL129C MYO3 "One of two type I myosins; localizes to actin cortical patches; deletion of MYO3 has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization" Verified chr11:196348-200163 196348-200163 98.7% 91.58 148.65 115.47 109.89 165.90 203.59 120.11 112.68 184.75 0.44 0.46 0.77 0.71 1.19 Frag>80[3451,3452]
YKL128C PMU1 "Putative phosphomutase, contains a region homologous to the active site of phosphomutases; overexpression suppresses the histidine auxotrophy of an ade3 ade16 ade17 triple mutant and the temperature sensitivity of a tps2 mutant" Verified chr11:200528-201415 200528-201415 98.9% 356.31 339.23 305.08 309.63 367.69 233.36 347.77 307.36 300.53 1.28 1.25 1.25 -0.03 0.15 Covered[3453]
YKL127W PGM1 "Phosphoglucomutase, minor isoform; catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism" Verified chr11:203185-204897 203185-204897 98.4% 289.46 239.63 294.20 265.73 179.72 121.00 264.54 279.97 150.36 0.98 1.14 0.62 -0.90 -0.48 Matched[3454]
YKL126W YPK1 "Serine/threonine protein kinase required for receptor-mediated endocytosis; involved in sphingolipid-mediated and cell integrity signaling pathways; localized to the bud neck, cytosol and plasma membrane; homolog of mammalian kinase SGK" Verified chr11:205351-207393 205351-207393 98.7% 294.93 308.80 308.31 288.98 412.90 309.30 301.86 298.64 361.10 1.11 1.21 1.50 0.27 0.21 Matched[3455]
YKL125W RRN3 Protein required for transcription of rDNA by RNA polymerase I; transcription factor independent of DNA template; involved in recruitment of RNA polymerase I to rDNA Verified chr11:207891-209774 207891-209774 98.6% 123.24 79.65 70.50 41.44 42.51 23.68 101.44 55.97 33.10 0.37 0.23 0.14 -0.76 -0.47 Matched[3456]
YKL124W SSH4 "Vacuolar protein that presumably functions within the endosomal-vacuolar trafficking pathway, affecting events that determine whether plasma membrane proteins are degraded or routed to the plasma membrane" Verified chr11:210237-211976 210237-211976 98.7% 48.35 72.23 58.83 58.25 81.55 66.41 60.29 58.54 73.98 0.22 0.24 0.31 0.34 0.69 Matched[3457]
YKL123W "Dubious open reading frame, unlikely to encode a protein; partially overlaps the verified gene SSH4" Dubious chr11:211687-212067 211687-212067 98.9% 95.53 132.68 74.30 84.92 153.91 103.49 114.11 79.61 128.70 0.42 0.32 0.53 0.69 0.54 Covered/w/another[3457]
YKL122C SRP21 "Subunit of the signal recognition particle (SRP), which functions in protein targeting to the endoplasmic reticulum membrane; not found in mammalian SRP; forms a pre-SRP structure in the nucleolus that is translocated to the cytoplasm" Verified chr11:212139-212642 212139-212642 99.1% 904.53 838.49 748.44 714.42 574.34 414.24 871.51 731.43 494.29 3.22 2.97 2.05 -0.57 -0.88 Matched[3458]
YKL121W Putative protein of unknown function Uncharacterized chr11:213786-216344 213786-216344 98.9% 82.96 97.97 88.89 105.08 141.82 158.41 90.47 96.98 150.12 0.33 0.39 0.62 0.63 1.35 Matched[3460]
YKL120W OAC1 "Mitochondrial inner membrane transporter, transports oxaloacetate, sulfate, and thiosulfate; member of the mitochondrial carrier family" Verified chr11:216988-217962 216988-217962 98.8% 398.62 418.34 330.10 241.87 74.74 35.29 408.48 285.99 55.02 1.51 1.16 0.23 -2.38 -2.16 Matched[3461]
YKL118W "Dubious open reading frame, unlikely to encode a protein; partially overlaps the verified gene VPH2" Dubious chr11:218770-219081 218770-219081 99.6% 67.55 102.94 99.72 102.94 96.50 48.25 85.24 101.33 72.38 0.31 0.41 0.30 -0.49 0.03 Frag<80[3462]
YKL119C VPH2 "Integral membrane protein required for vacuolar H+-ATPase (V-ATPase) function, although not an actual component of the V-ATPase complex; functions in the assembly of the V-ATPase; localized to the endoplasmic reticulum (ER)" Verified chr11:218214-218861 218214-218861 99.2% 286.14 301.69 275.25 227.05 265.92 147.74 293.92 251.15 206.83 1.08 1.02 0.86 -0.28 -0.68 Matched[3462]
YKL117W SBA1 Co-chaperone that binds to and regulates Hsp90 family chaperones; important for pp60v-src activity in yeast; homologous to the mammalian p23 proteins and like p23 can regulate telomerase activity Verified chr11:219968-220618 219968-220618 97.0% 2109.26 2003.17 2015.84 2025.34 3713.38 2999.21 2056.22 2020.59 3356.29 7.59 8.20 13.91 0.73 0.03 Matched[3463]
YKL116C PRR1 "Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor" Verified chr11:220988-222544 220988-222544 99.0% 116.73 107.65 104.40 107.00 88.84 57.07 112.19 105.70 72.95 0.41 0.43 0.30 -0.53 -0.15 Matched[3464]
YKL115C "Dubious open reading frame, unlikely to encode a protein; partially overlaps the verified gene PRR1" Dubious chr11:222537-222929 222537-222929 98.7% 54.13 43.82 36.09 18.04 51.55 46.40 48.97 27.06 48.97 0.18 0.11 0.20 0.86 0.05 Covered/w/another[3464]
YKL114C APN1 "Major apurinic/apyrimidinic endonuclease, 3'-repair diesterase involved in repair of DNA damage by oxidation and alkylating agents; also functions as a 3'-5' exonuclease to repair 7,8-dihydro-8-oxodeoxyguanosine" Verified chr11:222996-224099 222996-224099 99.3% 273.65 217.10 224.39 234.43 192.47 128.62 245.37 229.41 160.54 0.91 0.93 0.67 -0.51 -0.36 Covered/w/another[3465]
YKL113C RAD27 "5' to 3' exonuclease, 5' flap endonuclease, required for Okazaki fragment processing and maturation as well as for long-patch base-excision repair; member of the S. pombe RAD2/FEN1 family" Verified chr11:224371-225519 224371-225519 99.4% 273.27 203.20 231.23 196.20 75.33 41.17 238.24 213.71 58.25 0.88 0.87 0.24 -1.88 -1.84 Covered/w/another[3465]
YKL112W ABF1 "DNA binding protein with possible chromatin-reorganizing activity involved in transcriptional activation, gene silencing, and DNA replication and repair" Verified chr11:226214-228409 226214-228409 98.7% 221.93 144.88 235.31 190.09 219.62 219.16 183.40 212.70 219.39 0.68 0.86 0.91 0.04 0.60 Matched[3466]
YKL111C "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; partially overlaps the verified essential gene ABF1" Dubious chr11:228108-228443 228108-228443 98.4% 335.60 217.69 374.91 290.25 450.49 320.48 276.64 332.58 385.49 1.02 1.35 1.60 0.21 0.32 Covered/w/another[3466]
YKL110C KTI12 "Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p" Verified chr11:228583-229524 228583-229524 98.9% 212.55 212.55 159.95 145.99 211.48 112.72 212.55 152.97 162.10 0.78 0.62 0.67 0.08 -0.20 Matched[3467]
YKL109W HAP4 "Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; provides the principal activation function of the complex" Verified chr11:231871-233535 231871-233535 98.9% 498.06 606.79 587.35 697.90 714.30 608.00 552.43 642.62 661.15 2.04 2.61 2.74 0.04 0.10 Covered[3470]
YKL108W SLD2 "Protein required for DNA replication, phosphorylated in S phase by S-phase cyclin-dependent kinases (Cdks), phosphorylation is essential for DNA replication and for complex formation with Dpb11p; potential Cdc28p substrate" Verified chr11:234070-235431 234070-235431 98.4% 82.05 72.35 91.75 73.10 69.37 47.74 77.20 82.42 58.55 0.28 0.33 0.24 -0.49 -0.36 Matched[3471]
YKL107W Putative protein of unknown function Uncharacterized chr11:235785-236714 235785-236714 98.4% 14.20 13.11 14.20 6.55 27.31 12.02 13.65 10.38 19.66 0.05 0.04 0.08 0.92 1.56
YKL106C-A Putative protein of unknown function; identified by homology to uncharacterized proteins in other fungi Uncharacterized chr11:236791-236910 236791-236910 98.8% 0.00 0.00 8.43 8.43 8.43 0.00 0.00 8.43 4.22 0.00 0.03 0.02 -1.00 0.58 Covered/w/another[3472]
YKL106W AAT1 "Mitochondrial aspartate aminotransferase, catalyzes the conversion of oxaloacetate to aspartate in aspartate and asparagine biosynthesis" Verified chr11:237180-238535 237180-238535 98.8% 158.99 157.50 134.36 108.98 124.66 79.87 158.25 121.67 102.26 0.58 0.49 0.42 -0.25 0.93 Matched[3472]
YKL105C Putative protein of unknown function Uncharacterized chr11:238829-242227 238829-242227 98.7% 88.25 112.11 91.53 106.74 112.40 145.50 100.18 99.14 128.95 0.37 0.40 0.53 0.38 0.83 Matched[3473]
YKL104C GFA1 "Glutamine-fructose-6-phosphate amidotransferase, catalyzes the formation of glucosamine-6-P and glutamate from fructose-6-P and glutamine in the first step of chitin biosynthesis" Verified chr11:242864-245017 242864-245017 99.1% 532.55 444.96 509.60 475.88 493.68 451.52 488.76 492.74 472.60 1.80 2.00 1.96 -0.06 0.21 Frag>80[3474,3475,3476]
YKL103C LAP4 "Vacuolar aminopeptidase, often used as a marker protein in studies of autophagy and cytosol to vacuole targeting (CVT) pathway" Verified chr11:245782-247326 245782-247326 98.8% 472.76 946.17 561.81 633.18 2130.03 2249.86 709.46 597.50 2189.94 2.62 2.43 9.07 1.87 1.70 Matched[3477]
YKL102C Dubious open reading frame unlikely to encode a functional protein; deletion confers sensitivity to citric acid; predicted protein would include a thiol-disulfide oxidoreductase active site Dubious chr11:247706-248011 247706-248011 98.6% 6.63 9.94 6.63 6.63 19.89 13.26 8.29 6.63 16.57 0.03 0.03 0.07 1.32 0.38 Matched[3478]
YKL101W HSL1 "Nim1p-related protein kinase that regulates the morphogenesis and septin checkpoints; associates with the assembled septin filament; required along with Hsl7p for bud neck recruitment, phosphorylation, and degradation of Swe1p" Verified chr11:248564-253120 248564-253120 98.8% 365.26 289.32 309.31 267.34 98.59 120.13 327.29 288.32 109.36 1.21 1.17 0.45 -1.40 -0.51 Matched[3479]
YKL100W-A Putative protein of unknown function; identified by expression profiling and mass spectrometry Dubious chr11:253803-253892 253803-253892 99.2% 414.57 436.97 403.36 537.82 806.72 537.82 425.77 470.59 672.27 1.57 1.91 2.79 0.51 NaN Covered/w/another[3480]
YKL100C Putative protein of unknown function with similarity to a human minor histocompatibility antigen; YKL100C is not an essential gene Uncharacterized chr11:253341-255104 253341-255104 98.9% 314.00 361.55 374.73 380.46 689.30 449.22 337.77 377.60 569.26 1.25 1.53 2.36 0.59 1.07 Matched[3480]
YKL099C UTP11 "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" Verified chr11:255364-256116 255364-256116 99.3% 268.93 159.22 191.33 145.84 28.10 4.01 214.07 168.58 16.06 0.79 0.68 0.07 -3.39 -4.57 Matched[3481]
YKL098W Putative protein of unknown function Uncharacterized chr11:256414-257487 256414-257487 98.6% 129.38 118.99 114.27 85.94 102.94 73.66 124.18 100.10 88.30 0.46 0.41 0.37 -0.18 -0.07 Matched[3482]
YKL097C "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species" Dubious chr11:258147-258557 258147-258557 98.2% 4.95 4.95 2.48 4.95 4.95 14.86 4.95 3.72 9.91 0.02 0.02 0.04 1.42 -0.02
YKL096C-B "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr11:258717-258866 258717-258866 99.6% 1459.01 1592.86 1566.09 1673.17 756.27 709.43 1525.93 1619.63 732.85 5.63 6.57 3.04 -1.14 NaN Matched[3483]
YKL096W-A CWP2 "Covalently linked cell wall mannoprotein, major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored" Verified chr11:258897-259175 258897-259175 99.3% 20350.73 22642.80 20188.30 17896.22 10052.64 6475.56 21496.77 19042.26 8264.10 79.35 77.30 34.24 -1.20 -3.01 Matched[3483]
YKL096W CWP1 "Cell wall mannoprotein, linked to a beta-1,3- and beta-1,6-glucan heteropolymer through a phosphodiester bond; involved in cell wall organization" Verified chr11:260776-261495 260776-261495 98.6% 656.11 487.15 1420.63 1085.53 6570.93 4636.40 571.63 1253.08 5603.66 2.11 5.09 23.22 2.16 2.18 Matched[3486]
YKL095W YJU2 "Essential nuclear protein; putative spliceosomal component involved in mRNA splicing, based on computational analysis of large-scale protein-protein interaction data" Verified chr11:261921-262757 261921-262757 98.2% 55.95 52.30 71.76 43.79 42.57 34.06 54.13 57.77 38.31 0.20 0.23 0.16 -0.59 0.34 Matched[3487]
YKL094W YJU3 "Serine hydrolase with sequence similarity to monoglyceride lipase (MGL), localizes to lipid particles" Verified chr11:262993-263934 262993-263934 98.6% 362.92 440.46 393.07 331.69 1059.68 721.53 401.69 362.38 890.60 1.48 1.47 3.69 1.30 1.29 Matched[3488]
YKL093W MBR1 "Protein involved in mitochondrial functions and stress response; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants" Verified chr11:264433-265452 264433-265452 98.8% 63.49 65.48 61.51 68.46 167.67 123.02 64.49 64.98 145.34 0.24 0.26 0.60 1.16 1.77 Covered/w/another[3489]
YKL092C BUD2 GTPase activating factor for Rsr1p/Bud1p required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types Verified chr11:265789-269103 265789-269103 99.3% 89.59 76.53 73.49 64.08 54.05 54.97 83.06 68.78 54.51 0.31 0.28 0.23 -0.34 -0.08 Covered/w/another[3489]
YKL091C "Putative homolog of Sec14p, which is a phosphatidylinositol/phosphatidylcholine transfer protein involved in lipid metabolism; localizes to the nucleus" Verified chr11:269362-270294 269362-270294 99.0% 130.99 192.69 175.37 118.00 1396.48 628.96 161.84 146.68 1012.72 0.60 0.60 4.20 2.79 2.58 Matched[3490]
YKL090W CUE2 "Protein of unknown function; has two CUE domains that bind ubiquitin, which may facilitate intramolecular monoubiquitination" Verified chr11:271522-272853 271522-272853 98.8% 96.48 88.12 74.45 53.94 113.95 67.61 92.30 64.19 90.78 0.34 0.26 0.38 0.50 0.98 Covered[3491]
YKL089W MIF2 "Kinetochore protein with homology to human CENP-C, required for structural integrity of the spindle during anaphase spindle elongation, interacts with histones H2A, H2B, and H4, phosphorylated by Ipl1p" Verified chr11:273038-274687 273038-274687 98.5% 85.57 82.49 74.49 67.71 50.48 36.94 84.03 71.10 43.71 0.31 0.29 0.18 -0.70 -0.68 Matched[3492]
YKL088W "Predicted phosphopantothenoylcysteine decarboxylase, may be involved in coenzyme A biosynthesis; interacts with Sis2p and Vhs3p" Uncharacterized chr11:274927-276642 274927-276642 98.3% 122.70 149.37 125.66 119.74 126.26 149.97 136.04 122.70 138.11 0.50 0.50 0.57 0.17 0.43 Matched[3493]
YKL087C CYT2 "Cytochrome c1 heme lyase, involved in maturation of cytochrome c1, which is a subunit of the mitochondrial ubiquinol-cytochrome-c reductase; links heme covalently to apocytochrome c1" Verified chr11:276833-277507 276833-277507 98.9% 248.66 248.66 232.18 238.17 387.97 224.69 248.66 235.18 306.33 0.92 0.95 1.27 0.38 0.48 Matched[3494]
YKL086W SRX1 "Sulfiredoxin, contributes to oxidative stress resistance by reducing cysteine-sulfinic acid groups in the peroxiredoxins Tsa1p and Ahp1p that are formed upon exposure to oxidants; conserved in higher eukaryotes" Verified chr11:277925-278308 277925-278308 98.0% 21.25 31.88 47.82 37.19 143.46 85.01 26.57 42.51 114.24 0.10 0.17 0.47 1.43 1.23 Matched[3495]
YKL085W MDH1 "Mitochondrial malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the tricarboxylic acid (TCA) cycle; phosphorylated" Verified chr11:278767-279771 278767-279771 98.5% 1227.77 1835.59 1442.83 1979.97 3320.82 2685.74 1531.68 1711.40 3003.28 5.65 6.95 12.44 0.81 0.44 Matched[3496]
YKL084W HOT13 "Mitochondrial intermembrane space protein, first component of a pathway mediating assembly of small TIM (Translocase of the Inner Membrane) complexes which escort hydrophobic inner membrane proteins en route to the TIM22 complex" Verified chr11:280153-280503 280153-280503 99.3% 154.91 94.67 152.04 143.44 97.54 57.38 124.79 147.74 77.46 0.46 0.60 0.32 -0.93 -0.60 Matched[3497]
YKL083W "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; partially overlaps the verified essential gene RRP14" Dubious chr11:280565-281179 280565-281179 98.1% 560.22 346.41 348.07 255.25 79.56 39.78 453.31 301.66 59.67 1.67 1.22 0.25 -2.34 -0.40 Frag<80[3497]
YKL082C RRP14 "Essential protein, constituent of 66S pre-ribosomal particles; interacts with proteins involved in ribosomal biogenesis and cell polarity; member of the SURF-6 family" Verified chr11:280669-281973 280669-281973 99.6% 520.30 342.51 319.42 252.45 72.35 33.10 431.40 285.93 52.72 1.59 1.16 0.22 -2.44 -2.28 Matched[3498]
YKL081W TEF4 Translation elongation factor EF-1 gamma Verified chr11:282535-284099 282535-282739,283066-284099 96.0% 6198.00 3753.94 5226.93 5102.50 1744.55 1374.62 4975.97 5164.72 1559.59 18.37 20.96 6.46 -1.73 -2.36 Frag>80[3499,3500]
YKL080W VMA5 "Subunit C of the eight-subunit V1 peripheral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane" Verified chr11:284674-285852 284674-285852 99.1% 1616.78 1864.13 1517.49 1573.12 958.60 810.53 1740.45 1545.31 884.56 6.42 6.27 3.67 -0.80 -0.62 Frag>80[3501,3502]
YKL079W SMY1 "Protein that interacts with Myo2p, proposed to be involved in exocytosis; N-terminal domain is related to the motor domain of kinesins" Verified chr11:286247-288217 286247-288217 98.8% 163.81 153.02 127.35 104.24 194.62 142.24 158.41 115.79 168.43 0.58 0.47 0.70 0.54 0.36 Matched[3503]
YKL078W DHR2 "Predominantly nucleolar DEAH-box ATP-dependent RNA helicase, required for 18S rRNA synthesis" Verified chr11:288489-290696 288489-290696 98.6% 56.47 22.50 19.28 13.77 1.84 4.13 39.48 16.53 2.98 0.15 0.07 0.01 -2.47 -2.88
YKL077W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole Uncharacterized chr11:291097-292275 291097-292275 98.8% 626.13 590.92 547.97 531.65 456.93 304.05 608.52 539.81 380.49 2.25 2.19 1.58 -0.50 -0.28 Matched[3504]
YKL076C PSY1 "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 69% of ORF overlaps the uncharacterized ORF YKL075C" Dubious chr11:292482-292865 292482-292865 99.3% 152.18 152.18 110.20 118.07 241.39 104.95 152.18 114.14 173.17 0.56 0.46 0.72 0.60 0.22 Covered/w/another[3505]
YKL075C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; proposed to be involved in resistance to streptozotocin and camptothecin Uncharacterized chr11:292600-293952 292600-293952 99.4% 111.57 91.49 96.70 87.77 112.32 72.89 101.53 92.23 92.61 0.37 0.37 0.38 0.01 0.02 Matched[3505]
YKL074C MUD2 "Protein involved in early pre-mRNA splicing; component of the pre-mRNA-U1 snRNP complex, the commitment complex; interacts with Msl5p/BBP splicing factor and Sub2p; similar to metazoan splicing factor U2AF65" Verified chr11:294254-295837 294254-295837 99.3% 84.59 87.77 73.77 68.69 42.61 29.89 86.18 71.23 36.25 0.32 0.29 0.15 -0.97 -0.71 Matched[3506]
YKL073W LHS1 "Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide translocation and folding; member of the Hsp70 family; localizes to the lumen of the ER; regulated by the unfolded protein response pathway" Verified chr11:296074-298719 296074-298719 98.7% 302.00 240.37 251.09 259.89 244.96 154.63 271.18 255.49 199.80 1.00 1.04 0.83 -0.35 0.20 Matched[3507]
YKL072W STB6 Protein that binds Sin3p in a two-hybrid assay Verified chr11:299226-301526 299226-301526 98.9% 71.66 90.56 61.11 53.63 42.20 32.53 81.11 57.37 37.37 0.30 0.23 0.15 -0.62 -0.61 Matched[3508]
YKL071W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr11:304758-305528 304758-305528 98.9% 106.20 106.20 97.02 51.13 39.33 30.16 106.20 74.08 34.74 0.39 0.30 0.14 -1.09 -0.27 Covered/w/another[3509]
YKL070W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr11:305855-306364 305855-306364 98.6% 99.44 133.26 81.54 79.56 99.44 65.63 116.35 80.55 82.54 0.43 0.33 0.34 0.04 0.17 Covered/w/another[3509]
YKL069W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus Uncharacterized chr11:306929-307471 306929-307471 98.6% 169.89 194.17 196.03 216.57 425.67 302.45 182.03 206.30 364.06 0.67 0.84 1.51 0.82 0.54 Matched[3510]
YKL068W-A Putative protein of unknown function; identified by homology to Ashbya gossypii Uncharacterized chr11:308850-309086 308850-309086 98.6% 201.14 295.29 201.14 175.46 106.99 64.19 248.22 188.30 85.59 0.92 0.76 0.35 -1.14 NaN Covered/w/another[3511]
YKL068W NUP100 Subunit of the nuclear pore complex (NPC) that is localized to both sides of the pore; contains a repetitive GLFG motif that interacts with mRNA export factor Mex67p and with karyopherin Kap95p; homologous to Nup116p Verified chr11:309843-312722 309843-312722 98.9% 194.81 159.01 157.95 121.10 65.99 68.45 176.91 139.53 67.22 0.65 0.57 0.28 -1.05 -0.05 Covered/w/another[3511]
YKL067W YNK1 "Nucleoside diphosphate kinase, catalyzes the transfer of gamma phosphates from nucleoside triphosphates, usually ATP, to nucleoside diphosphates by a mechanism that involves formation of an autophosphorylated enzyme intermediate" Verified chr11:314456-314917 314456-314917 98.5% 1591.35 1901.27 1488.05 1521.02 3488.23 2015.57 1746.31 1504.53 2751.90 6.45 6.11 11.40 0.87 0.68 Frag>80[3512,3513,3514]
YKL066W "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; partially overlaps the verified gene YNK1" Dubious chr11:314925-315368 314925-315368 99.2% 506.53 608.74 458.83 463.37 1235.66 572.40 557.64 461.10 904.03 2.06 1.87 3.75 0.97 -0.44 Frag>80[3512,3513,3514,3515]
YKL065W-A Putative protein of unknown function Uncharacterized chr11:315598-315819 315598-315819 98.8% 27.35 36.47 36.47 22.79 173.22 123.08 31.91 29.63 148.15 0.12 0.12 0.61 2.32 NaN Matched[3515]
YKL065C YET1 "Endoplasmic reticulum transmembrane protein; may interact with ribosomes, based on co-purification experiments; homolog of human BAP31 protein" Verified chr11:316081-316701 316081-316701 99.0% 912.44 1188.94 975.87 1089.73 2698.29 1658.99 1050.69 1032.80 2178.64 3.88 4.19 9.03 1.08 0.61 Matched[3516]
YKL064W MNR2 "Putative magnesium transporter; has similarity to Alr1p and Alr2p, which mediate influx of Mg2+ and other divalent cations" Verified chr11:317408-320317 317408-320317 98.7% 242.96 251.32 207.81 214.42 255.15 221.73 247.14 211.11 238.44 0.91 0.86 0.99 0.18 0.41 Covered/w/another[3517]
YKL063C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the Golgi Uncharacterized chr11:320659-321162 320659-321162 99.4% 530.76 634.52 403.06 494.85 624.54 331.23 582.64 448.95 477.88 2.15 1.82 1.98 0.09 -0.34 Covered/w/another[3517]
YKL062W MSN4 "Transcriptional activator related to Msn2p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression" Verified chr11:322872-324764 322872-324764 98.9% 213.64 354.65 338.09 372.27 264.38 190.14 284.14 355.18 227.26 1.05 1.44 0.94 -0.64 -0.36 Matched[3519]
YKL061W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endosome Uncharacterized chr11:325415-325756 325415-325756 98.3% 175.46 163.57 148.70 142.75 231.97 148.70 169.52 145.72 190.33 0.63 0.59 0.79 0.39 0.04 Matched[3520]
YKL060C FBA1 "Fructose 1,6-bisphosphate aldolase, required for glycolysis and gluconeogenesis; catalyzes conversion of fructose 1,6 bisphosphate to glyceraldehyde-3-P and dihydroxyacetone-P; locates to mitochondrial outer surface upon oxidative stress" Verified chr11:326052-327131 326052-327131 98.7% 55586.60 63058.75 53159.68 51482.31 40139.47 34679.59 59322.68 52320.99 37409.53 218.99 212.38 155.00 -0.48 -1.42 Frag>80[3520,3521,3522,3523,3524]
YKL059C MPE1 "Essential conserved subunit of CPF (cleavage and polyadenylation factor), plays a role in 3' end formation of mRNA via the specific cleavage and polyadenylation of pre-mRNA, contains a putative RNA-binding zinc knuckle motif" Verified chr11:327762-329087 327762-329087 99.0% 117.29 95.96 113.48 92.16 100.53 65.50 106.63 102.82 83.02 0.39 0.42 0.34 -0.31 0.18 Matched[3525]
YKL058W TOA2 "TFIIA small subunit; involved in transcriptional activation, acts as antirepressor or as coactivator; homologous to smallest subunit of human and Drosophila TFIIA" Verified chr11:329810-330178 329810-330178 98.4% 473.83 476.58 531.68 454.55 504.13 355.37 475.21 493.11 429.75 1.75 2.00 1.78 -0.20 -0.60 Matched[3526]
YKL057C NUP120 "Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), required for even distribution of NPCs around the nuclear envelope, involved in establishment of a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p" Verified chr11:330500-333613 330500-333613 99.2% 147.69 158.38 142.51 123.72 91.66 75.46 153.03 133.11 83.56 0.56 0.54 0.35 -0.67 -0.59 Matched[3527]
YKL056C TMA19 Protein that associates with ribosomes; homolog of translationally controlled tumor protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and relocates to the mitochondrial outer surface upon oxidative stress Verified chr11:334056-334559 334056-334559 99.0% 11513.83 8101.58 10096.40 9527.02 6092.72 5068.25 9807.70 9811.71 5580.49 36.20 39.83 23.12 -0.81 -1.81 Frag>80[3528,3529]
YKL055C OAR1 "Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase, may comprise a type II mitochondrial fatty acid synthase along with Mct1p" Verified chr11:334965-335801 334965-335801 99.0% 44.63 53.08 39.81 41.02 13.27 33.78 48.86 40.41 23.52 0.18 0.16 0.10 -0.78 -0.77 Matched[3530]
YKL054C DEF1 "RNAPII degradation factor, forms a complex with Rad26p in chromatin, enables ubiquitination and proteolysis of RNAPII present in an elongation complex" Verified chr11:336181-338397 336181-338397 96.9% 822.19 641.55 677.40 495.83 541.92 476.28 731.87 586.61 509.10 2.70 2.38 2.11 -0.20 0.33 Frag>80[3531,3532,3533]
YKL053C-A MDM35 Mitochondrial intermembrane space cysteine motif protein; mutation affects mitochondrial distribution and morphology Verified chr11:338826-339086 338826-339086 99.2% 687.70 745.65 722.47 722.47 1522.22 815.20 716.68 722.47 1168.71 2.65 2.93 4.84 0.69 -0.12 Matched[3533]
YKL053W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF ASK1" Dubious chr11:339216-339590 339216-339590 99.0% 145.42 220.83 153.50 121.18 220.83 113.11 183.12 137.34 166.97 0.68 0.56 0.69 0.28 0.24 Matched[3534]
YKL052C ASK1 "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; phosphorylated during the cell cycle by cyclin-dependent kinases" Verified chr11:339312-340190 339312-340190 99.1% 145.74 216.89 164.10 154.92 173.28 123.94 181.31 159.51 148.61 0.67 0.65 0.62 -0.10 0.12 Frag>80[3533,3534,3535,3536]
YKL051W SFK1 "Plasma membrane protein that may act together with or upstream of Stt4p to generate normal levels of the essential phospholipid PI4P, at least partially mediates proper localization of Stt4p to the plasma membrane" Verified chr11:340956-342017 340956-342017 99.0% 296.62 335.60 234.83 186.34 328.95 344.16 316.11 210.58 336.56 1.17 0.85 1.39 0.68 0.81 Matched[3537]
YKL050C Protein of unknown function; the YKL050W protein is a target of the SCFCdc4 ubiquitin ligase complex and YKL050W transcription is regulated by Azf1p Verified chr11:342496-345264 342496-345264 99.2% 32.02 32.02 19.65 12.37 16.74 23.65 32.02 16.01 20.20 0.12 0.06 0.08 0.33 0.84 Frag>80[3538,3539]
YKL049C CSE4 "Centromere protein that resembles histones, required for proper kinetochore function; homolog of human CENP-A" Verified chr11:345719-346408 345719-346408 99.5% 107.84 99.10 115.13 99.10 104.92 81.61 103.47 107.11 93.27 0.38 0.43 0.39 -0.20 -0.16 Matched[3540]
YKL048C ELM1 "Serine/threonine protein kinase that regulates cellular morphogenesis, septin behavior, and cytokinesis; required for the regulation of other kinases; forms part of the bud neck ring" Verified chr11:346858-348780 346858-348780 99.2% 68.14 77.05 67.09 64.47 47.70 49.27 72.60 65.78 48.49 0.27 0.27 0.20 -0.44 0.37 Matched[3541]
YKL047W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr11:349107-350657 349107-350657 99.0% 93.13 117.23 80.76 69.04 31.26 31.91 105.18 74.90 31.59 0.39 0.30 0.13 -1.25 -0.44 Matched[3542]
YKL046C DCW1 "Putative mannosidase, GPI-anchored membrane protein required for cell wall biosynthesis in bud formation;homologous to Dfg5p" Verified chr11:350919-352268 350919-352268 99.1% 655.78 557.83 588.48 578.02 446.41 381.36 606.80 583.25 413.88 2.24 2.37 1.71 -0.49 -0.18 Matched[3543]
YKL045W PRI2 "Subunit of DNA primase, which is required for DNA synthesis and double-strand break repair" Verified chr11:353137-354723 353137-354723 98.6% 195.47 153.31 173.75 137.98 74.74 59.41 174.39 155.86 67.07 0.64 0.63 0.28 -1.22 -1.46 Frag>80[3544,3545]
YKL044W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr11:355966-356286 355966-356286 99.2% 194.61 197.75 326.45 172.64 131.83 150.67 196.18 249.54 141.25 0.72 1.01 0.59 -0.82 -0.21 Matched[3546]
YKL043W PHD1 "Transcriptional activator that enhances pseudohyphal growth; regulates expression of FLO11, an adhesin required for pseudohyphal filament formation; similar to StuA, an A. nidulans developmental regulator; potential Cdc28p substrate" Verified chr11:356392-357492 356392-357492 98.9% 596.26 764.38 847.99 576.96 399.65 509.90 680.32 712.48 454.77 2.51 2.89 1.88 -0.65 0.42 Frag>80[3546,3547]
YKL042W SPC42 "Central plaque component of spindle pole body (SPB); involved in SPB duplication, may facilitate attachment of the SPB to the nuclear membrane" Verified chr11:358119-359210 358119-359210 98.8% 123.31 113.11 133.51 115.89 102.91 90.86 118.21 124.70 96.89 0.44 0.51 0.40 -0.36 -0.45 Frag>80[3548,3549]
YKL041W VPS24 One of four subunits of the endosomal sorting complex required for transport III (ESCRT-III); forms an ESCRT-III subcomplex with Did4p; involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway Verified chr11:359786-360460 359786-360460 98.1% 317.18 323.22 268.85 255.25 569.41 339.84 320.20 262.05 454.63 1.18 1.06 1.88 0.79 0.37 Matched[3550]
YKL040C NFU1 "Protein involved in iron metabolism in mitochondria; similar to NifU, which is a protein required for the maturation of the Fe/S clusters of nitrogenase in nitrogen-fixing bacteria" Verified chr11:360701-361471 360701-361471 99.3% 336.87 287.25 330.34 322.51 313.37 214.13 312.06 326.42 263.75 1.15 1.33 1.09 -0.31 -0.36 Matched[3551]
YKL039W PTM1 "Protein of unknown function, copurifies with late Golgi vesicles containing the v-SNARE Tlg2p" Verified chr11:362265-363836 362265-363836 98.9% 332.66 395.08 431.11 356.47 419.53 373.20 363.87 393.79 396.36 1.34 1.60 1.64 0.01 0.68 Matched[3553]
YKL038W RGT1 Glucose-responsive transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose; binds to promoters and acts both as a transcriptional activator and repressor Verified chr11:365248-368760 365248-368760 98.7% 76.40 89.08 87.35 89.08 113.30 147.31 82.74 88.22 130.30 0.31 0.36 0.54 0.56 1.17 Matched[3556]
YKL037W Putative protein of unknown function Uncharacterized chr11:369008-369364 369008-369364 99.3% 31.04 19.76 39.51 31.04 42.33 22.58 25.40 35.28 32.46 0.09 0.14 0.13 -0.12 1.72 Covered/w/another[3556]
YKL035W UGP1 "UDP-glucose pyrophosphorylase (UGPase), catalyses the reversible formation of UDP-Glc from glucose 1-phosphate and UTP, involved in a wide variety of metabolic pathways, expression modulated by Pho85p through Pho4p" Verified chr11:369534-371033 369534-371033 98.8% 1115.81 2367.89 1768.16 1950.98 10530.70 7921.97 1741.85 1859.57 9226.33 6.43 7.55 38.23 2.31 1.56 Matched[3557]
YKL036C "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; partially overlaps the essential gene UGP1 gene and uncharacterized ORF YKL037W" Dubious chr11:369171-369563 369171-369563 99.1% 189.97 336.29 243.88 364.53 1501.76 1221.95 263.13 304.20 1361.86 0.97 1.23 5.64 2.16 0.42
YKL034W TUL1 "Golgi-localized RING-finger ubiquitin ligase (E3), involved in ubiquitinating and sorting membrane proteins that contain polar transmembrane domains to multivesicular bodies for delivery to the vacuole for quality control purposes" Verified chr11:371472-373748 371472-373748 99.0% 102.02 125.08 116.21 120.65 112.66 87.82 113.55 118.43 100.24 0.42 0.48 0.42 -0.24 0.24 Matched[3558]
YKL033W-A Putative protein of unknown function; similar to uncharacterized proteins from other fungi Uncharacterized chr11:374148-374858 374148-374858 98.7% 572.99 731.20 605.77 574.42 669.91 417.63 652.10 590.09 543.77 2.41 2.40 2.25 -0.12 -0.86 Matched[3559]
YKL033W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YKL033W is an essential gene" Uncharacterized chr11:375099-378215 375099-378215 98.9% 40.55 41.52 37.95 34.39 16.87 17.19 41.04 36.17 17.03 0.15 0.15 0.07 -1.09 -0.81 Matched[3560]
YKL032C IXR1 "Protein that binds DNA containing intrastrand cross-links formed by cisplatin, contains two HMG (high mobility group box) domains, which confer the ability to bend cisplatin-modified DNA; mediates aerobic transcriptional repression of COX5b" Verified chr11:379708-381501 379708-381501 96.9% 288.35 276.26 267.05 262.45 254.96 244.60 282.30 264.75 249.78 1.04 1.07 1.03 -0.08 0.22 Matched[3561]
YKL031W "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species" Dubious chr11:381715-382128 381715-382128 98.6% 12.25 49.01 24.50 12.25 26.96 26.96 30.63 18.38 26.96 0.11 0.07 0.11 0.55 0.42 Matched[3562]
YKL030W "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; partially overlaps the verified gene MAE1" Dubious chr11:382141-382746 382141-382746 95.7% 926.19 793.39 569.17 401.87 84.51 56.92 859.79 485.52 70.72 3.17 1.97 0.29 -2.78 -1.59 Covered/w/another[3563]
YKL029C MAE1 "Mitochondrial malic enzyme, catalyzes the oxidative decarboxylation of malate to pyruvate, which is a key intermediate in sugar metabolism and a precursor for synthesis of several amino acids" Verified chr11:382359-384368 382359-384368 98.6% 857.90 745.93 522.51 378.26 62.54 38.33 801.92 450.38 50.44 2.96 1.83 0.21 -3.16 -2.44 Matched[3563]
YKL028W TFA1 "TFIIE large subunit, involved in recruitment of RNA polymerase II to the promoter, activation of TFIIH, and promoter opening" Verified chr11:385401-386849 385401-386849 97.4% 367.85 396.20 338.79 290.59 267.20 244.52 382.02 314.69 255.86 1.41 1.28 1.06 -0.30 0.06 Matched[3565]
YKL027W "Protein of unknown function, localized to the mitochondrial outer membrane" Verified chr11:387205-388548 387205-388548 98.6% 130.61 117.02 147.98 120.04 123.82 92.11 123.82 134.01 107.96 0.46 0.54 0.45 -0.31 -0.02 Matched[3566]
YKL026C GPX1 Phospholipid hydroperoxide glutathione peroxidase induced by glucose starvation that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress Verified chr11:389023-389526 389023-389526 99.2% 77.99 123.98 61.99 75.99 925.85 595.90 100.98 68.99 760.87 0.37 0.28 3.15 3.46 2.92 Matched[3567]
YKL025C PAN3 "Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex, which acts to control poly(A) tail length and regulate the stoichiometry and activity of postreplication repair complexes" Verified chr11:389883-391922 389883-391922 99.0% 154.53 191.18 175.83 169.88 207.52 190.68 172.85 172.85 199.10 0.64 0.70 0.82 0.20 0.53 Matched[3568]
YKL024C URA6 "Uridylate kinase, catalyzes the seventh enzymatic step in the de novo biosynthesis of pyrimidines, converting uridine monophosphate (UMP) into uridine-5'-diphosphate (UDP)" Verified chr11:392169-392783 392169-392783 98.8% 607.49 602.55 614.08 548.22 342.43 271.64 605.02 581.15 307.04 2.23 2.36 1.27 -0.92 -0.76 Frag>80[3569,3570]
YKL023C-A Putative protein of unknown function Uncharacterized chr11:392789-393016 392789-393016 99.1% 371.82 358.54 478.05 433.79 243.45 221.32 365.18 455.92 232.39 1.35 1.85 0.96 -0.97 NaN Matched[3570]
YKL023W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr11:393364-394197 393364-394197 97.9% 121.25 181.26 165.34 146.97 274.34 193.51 151.26 156.15 233.93 0.56 0.63 0.97 0.58 0.49 Matched[3571]
YKL022C CDC16 "Subunit of the anaphase-promoting complex/cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; required for sporulation" Verified chr11:394369-396891 394369-396891 99.2% 77.14 92.73 67.15 63.15 71.55 45.57 84.93 65.15 58.56 0.31 0.26 0.24 -0.15 -0.03 Matched[3572]
YKL021C MAK11 "Protein involved in an early, nucleolar step of 60S ribosomal subunit biogenesis; essential for cell growth and replication of killer M1 dsRNA virus; contains four beta-transducin repeats" Verified chr11:396987-398393 396987-398393 99.3% 213.35 142.47 153.93 135.31 63.72 35.80 177.91 144.62 49.76 0.66 0.59 0.21 -1.54 -1.59 Frag>80[3573]
YKL020C SPT23 "ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Mga2p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting" Verified chr11:398475-401723 398475-401723 98.7% 123.16 128.46 113.80 121.91 128.77 174.60 125.81 117.86 151.69 0.46 0.48 0.63 0.36 0.91 Matched[3574]
YKL019W RAM2 Alpha subunit of both the farnesyltransferase and type I geranylgeranyltransferase that catalyze prenylation of proteins containing a CAAX consensus motif; essential protein required for membrane localization of Ras proteins and a-factor Verified chr11:402211-403161 402211-403161 98.7% 247.08 270.51 241.76 238.56 252.41 179.99 258.80 240.16 216.20 0.96 0.97 0.90 -0.15 0.00 Frag>80[3575,3576]
YKL018C-A Putative protein of unknown function; identified by homology; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr11:403223-403522 403223-403522 99.6% 254.46 264.51 271.21 207.59 314.73 204.24 259.49 239.40 259.49 0.96 0.97 1.08 0.12 -0.28 Matched[3576]
YKL018W SWD2 "Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lys 4 and is involved in telomeric silencing; subunit of CPF (cleavage and polyadenylation factor), a complex involved in RNAP II transcription termination" Verified chr11:403745-404734 403745-404734 99.0% 134.64 82.62 107.10 103.02 110.16 92.82 108.63 105.06 101.49 0.40 0.43 0.42 -0.05 0.41 Covered/w/another[3577]
YKL017C HCS1 Hexameric DNA polymerase alpha-associated DNA helicase A involved in lagging strand DNA synthesis; contains single-stranded DNA stimulated ATPase and dATPase activities; replication protein A stimulates helicase and ATPase activities Verified chr11:404833-406884 404833-406884 99.2% 67.33 66.84 69.78 65.85 55.53 45.21 67.08 67.82 50.37 0.25 0.28 0.21 -0.43 -0.03 Covered/w/another[3577]
YKL016C ATP7 "Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis" Verified chr11:407108-407632 407108-407632 99.2% 660.43 714.18 825.53 936.89 1299.74 990.64 687.30 881.21 1145.19 2.54 3.58 4.74 0.38 0.27 Matched[3578]
YKL015W PUT3 "Transcriptional activator of proline utilization genes, constitutively binds PUT1 and PUT2 promoter sequences and undergoes a conformational change to form the active state; has a Zn(2)-Cys(6) binuclear cluster domain" Verified chr11:408187-411126 408187-411126 99.0% 79.74 78.71 68.06 61.53 97.96 61.18 79.23 64.79 79.57 0.29 0.26 0.33 0.30 0.51 Matched[3579]
YKL014C URB1 "Nucleolar protein required for the normal accumulation of 25S and 5.8S rRNAs, associated with the 27SA2 pre-ribosomal particle; proposed to be involved in the biogenesis of the 60S ribosomal subunit" Verified chr11:411262-416556 411262-416556 99.2% 111.15 59.57 70.61 61.09 6.09 3.62 85.36 65.85 4.85 0.32 0.27 0.02 -3.76 -2.53 Frag>80[3580,3581,3582]
YKL013C ARC19 "Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches" Verified chr11:417151-417666 417151-417666 99.2% 628.96 711.00 734.43 697.32 1097.75 796.94 669.98 715.88 947.34 2.47 2.91 3.93 0.40 0.36 Matched[3583]
YKL012W PRP40 "U1 snRNP protein involved in splicing, interacts with the branchpoint-binding protein during the formation of the second commitment complex" Verified chr11:417953-419704 417953-419704 98.5% 148.37 148.95 142.57 140.25 166.33 131.56 148.66 141.41 148.95 0.55 0.57 0.62 0.07 0.34 Matched[3584]
YKL011C CCE1 "Mitochondrial cruciform cutting endonuclease, cleaves Holliday junctions formed during recombination of mitochondrial DNA" Verified chr11:419798-420859 419798-420859 99.3% 76.80 96.72 72.06 80.60 100.51 52.15 86.76 76.33 76.33 0.32 0.31 0.32 0.00 0.04 Matched[3585]
YKL010C UFD4 "Ubiquitin-protein ligase (E3) that interacts with Rpt4p and Rpt6p, two subunits of the 19S particle of the 26S proteasome; cytoplasmic E3 involved in the degradation of ubiquitin fusion proteins" Verified chr11:421067-425518 421067-425518 99.2% 86.01 94.84 69.71 68.58 95.97 124.03 90.42 69.15 110.00 0.33 0.28 0.46 0.67 0.97 Frag>80[3586,3587]
YKL009W MRT4 "Protein involved in mRNA turnover and ribosome assembly, localizes to the nucleolus" Verified chr11:425885-426595 425885-426595 98.8% 748.71 357.27 492.50 382.90 72.59 27.04 552.99 437.70 49.82 2.04 1.78 0.21 -3.14 -3.69 Frag>80[3588,3589]
YKL008C LAC1 "Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lag1p" Verified chr11:426938-428194 426938-428194 98.9% 434.16 820.88 380.29 369.84 408.43 265.32 627.52 375.06 336.87 2.32 1.52 1.40 -0.15 -0.11 Matched[3590]
YKL007W CAP1 Alpha subunit of the capping protein (CP) heterodimer (Cap1p and Cap2p) which binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches Verified chr11:428945-429751 428945-429751 98.7% 512.24 556.18 478.34 457.00 743.25 494.66 534.21 467.67 618.96 1.97 1.90 2.56 0.40 0.05 Frag>80[3591,3592,3593,3594]
YKL006C-A SFT1 "Intra-Golgi v-SNARE, required for transport of proteins between an early and a later Golgi compartment" Verified chr11:429841-430275 429841-430098,430240-430275 99.4% 369.70 356.01 195.12 253.32 287.55 143.77 362.86 224.22 215.66 1.34 0.91 0.89 -0.06 -0.75 Matched[3594]
YKL006W RPL14A "N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl14Bp and has similarity to rat L14 ribosomal protein; rpl14a csh5 double null mutant exhibits synthetic slow growth" Verified chr11:431549-432363 431549-431677,432076-432363 43.8% 7656.54 6275.41 7240.01 5908.20 1392.10 805.66 6965.97 6574.10 1098.88 25.71 26.69 4.55 -2.58 -3.84 Matched[3596]
YKL005C BYE1 "Negative regulator of transcription elongation, contains a TFIIS-like domain and a PHD finger, multicopy suppressor of temperature-sensitive ess1 mutations, probably binds RNA polymerase II large subunit" Verified chr11:432736-434520 432736-434520 99.3% 127.49 133.13 105.49 83.49 144.42 93.64 130.31 94.49 119.03 0.48 0.38 0.49 0.33 0.60 Matched[3597]
YKL004W AUR1 "Phosphatidylinositol:ceramide phosphoinositol transferase (IPC synthase), required for sphingolipid synthesis; can mutate to confer aureobasidin A resistance" Verified chr11:435223-436428 435223-436428 99.3% 475.99 450.94 436.74 364.93 133.61 114.41 463.47 400.84 124.01 1.71 1.63 0.51 -1.69 -1.11 Matched[3598]
YKL003C MRP17 "Mitochondrial ribosomal protein of the small subunit; MRP17 exhibits genetic interactions with PET122, encoding a COX3-specific translational activator" Verified chr11:436740-437135 436740-437135 99.0% 331.49 374.84 344.24 331.49 443.69 303.44 353.17 337.87 373.57 1.30 1.37 1.55 0.14 0.13 Matched[3599]
YKL002W DID4 "Class E Vps protein of the ESCRT-III complex, required for sorting of integral membrane proteins into lumenal vesicles of multivesicular bodies, and for delivery of newly synthesized vacuolar enzymes to the vacuole, involved in endocytosis" Verified chr11:437421-438187 437421-437480,437549-438187 98.2% 565.08 629.16 621.88 508.28 464.59 281.08 597.12 565.08 372.84 2.20 2.29 1.54 -0.60 -0.65 Matched[3600]
YKL001C MET14 "Adenylylsulfate kinase, required for sulfate assimilation and involved in methionine metabolism" Verified chr11:438420-439028 438420-439028 99.2% 143.94 150.56 125.74 91.00 137.32 82.72 147.25 108.37 110.02 0.54 0.44 0.46 0.02 0.02 Matched[3601]
YKR001C VPS1 "Dynamin-like GTPase required for vacuolar sorting; also involved in actin cytoskeleton organization, late Golgi-retention of some proteins, regulating peroxisome biogenesis" Verified chr11:440251-442365 440251-442365 99.1% 592.76 527.91 613.27 635.21 530.29 501.68 560.34 624.24 515.99 2.07 2.53 2.14 -0.27 0.39 Frag>80[3602,3603]
YKR002W PAP1 "Poly(A) polymerase, one of three factors required for mRNA 3'-end polyadenylation, forms multiprotein complex with polyadenylation factor I (PF I), also required for mRNA nuclear export; may also polyadenylate rRNAs" Verified chr11:442875-444581 442875-444581 98.7% 184.06 194.16 212.56 169.22 237.50 176.34 189.11 190.89 206.92 0.70 0.77 0.86 0.12 0.48 Matched[3604]
YKR003W OSH6 "Member of an oxysterol-binding protein family with overlapping, redundant functions in sterol metabolism and which collectively perform a function essential for viability; GFP-fusion protein localizes to the cell periphery" Verified chr11:445024-446370 445024-446370 98.8% 232.24 296.12 268.31 237.50 386.31 296.12 264.18 252.90 341.21 0.98 1.03 1.41 0.43 0.47 Matched[3605]
YKR004C ECM9 Non-essential protein of unknown function Verified chr11:446442-447679 446442-447349,447454-447679 99.1% 100.52 98.74 94.29 83.62 127.21 81.84 99.63 88.95 104.52 0.37 0.36 0.43 0.23 0.26 Matched[3606]
YKR005C Putative protein of unknown function Uncharacterized chr11:448164-449810 448164-449594,449664-449810 99.1% 19.82 24.29 13.42 15.34 23.01 8.31 22.05 14.38 15.66 0.08 0.06 0.06 0.12 0.46 Frag<80[3607,3608]
YKR006C MRPL13 "Mitochondrial ribosomal protein of the large subunit, not essential for mitochondrial translation" Verified chr11:450066-450860 450066-450860 99.0% 378.47 375.93 382.28 384.82 360.69 331.48 377.20 383.55 346.09 1.39 1.56 1.43 -0.15 0.13 Frag>80[3607,3608,3609]
YKR007W MEH1 "Component of the EGO complex, which is involved in the regulation of microautophagy, and of the GSE complex, which is required for proper sorting of amino acid permease Gap1p; loss results in a defect in vacuolar acidification" Verified chr11:451077-451631 451077-451631 98.2% 227.54 209.19 214.70 225.71 223.87 152.31 218.37 220.20 188.09 0.81 0.89 0.78 -0.23 -0.13 Matched[3610]
YKR008W RSC4 Component of the RSC chromatin remodeling complex; found in close proximity to nucleosomal DNA; displaced from the surface of nucleosomal DNA after chromatin remodeling Verified chr11:451844-453721 451844-453721 99.0% 172.03 177.41 143.54 149.99 164.51 109.13 174.72 146.76 136.82 0.64 0.60 0.57 -0.10 0.39 Matched[3611]
YKR009C FOX2 Multifunctional enzyme of the peroxisomal fatty acid beta-oxidation pathway; has 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities Verified chr11:453995-456697 453995-456697 99.1% 37.72 46.68 33.61 28.01 79.92 53.03 42.20 30.81 66.48 0.16 0.13 0.28 1.11 0.99 Frag>80[3612,3613]
YKR010C TOF2 Nonessential mitochondrial protein of unknown function with sequence similarity to Net1p; identified as a topoisomerase I (Top1p) binding protein; displays synthetic genetic interactions with TOP1 and HPR1 Verified chr11:458567-460882 458567-460882 99.2% 97.54 97.10 75.77 62.70 68.80 51.38 97.32 69.23 60.09 0.36 0.28 0.25 -0.20 -0.55 Matched[3614]
YKR011C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus Uncharacterized chr11:461278-462339 461278-462339 99.2% 167.97 199.29 265.72 321.71 1039.15 837.96 183.63 293.71 938.55 0.68 1.19 3.89 1.68 1.93 Frag>80[3615,3616]
YKR013W PRY2 "Protein of unknown function, has similarity to Pry1p and Pry3p and to the plant PR-1 class of pathogen related proteins" Verified chr11:463602-464591 463602-464591 99.0% 910.24 726.56 916.37 736.77 168.37 110.21 818.40 826.57 139.29 3.02 3.36 0.58 -2.57 -1.94 Frag>80[3617,3618,3619]
YKR012C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene PRY2" Dubious chr11:463382-463759 463382-463759 99.1% 333.59 242.86 341.60 298.90 93.41 58.71 288.22 320.25 76.06 1.06 1.30 0.32 -2.07 -1.33 Matched[3617]
YKR014C YPT52 "GTPase, similar to Ypt51p and Ypt53p and to mammalian rab5; required for vacuolar protein sorting and endocytosis" Verified chr11:465010-465714 465010-465714 99.4% 734.62 880.12 741.75 727.49 1369.39 865.85 807.37 734.62 1117.62 2.98 2.98 4.63 0.61 -0.01 Frag>80[3619,3620]
YKR015C Putative protein of unknown function Uncharacterized chr11:466604-468310 466604-468310 99.4% 36.54 38.31 28.88 34.18 42.43 28.29 37.42 31.53 35.36 0.14 0.13 0.15 0.17 1.08 Matched[3621]
YKR016W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr11:469360-470982 469360-470982 98.7% 214.08 247.78 277.12 348.27 507.42 409.43 230.93 312.69 458.43 0.85 1.27 1.90 0.55 0.92 Matched[3622]
YKR017C Putative protein of unknown function; contains a RING finger motif Uncharacterized chr11:471337-472992 471337-472992 99.3% 52.91 62.04 53.52 38.93 119.21 74.20 57.48 46.22 96.71 0.21 0.19 0.40 1.06 0.44 Matched[3623]
YKR018C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus Uncharacterized chr11:473366-475543 473366-475543 99.2% 315.67 311.05 318.91 317.06 386.49 419.36 313.36 317.99 402.92 1.16 1.29 1.67 0.34 0.69 Matched[3624]
YKR019C IRS4 "Protein involved in regulation of phosphatidylinositol 4,5-bisphosphate concentrations; Irs4p and Tax4p bind and activate the phosphatase Inp51p; mutation confers an increase in rDNA silencing" Verified chr11:475859-477706 475859-477706 99.0% 42.65 51.94 43.74 24.60 47.57 28.98 47.30 34.17 38.27 0.17 0.14 0.16 0.16 0.58 Matched[3625]
YKR020W VPS51 "Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; links the (VFT/GARP) complex to the SNARE Tlg1p" Verified chr11:477981-478475 477981-478475 98.2% 142.01 150.24 104.97 117.31 164.65 102.91 146.13 111.14 133.78 0.54 0.45 0.55 0.27 0.36 Covered/w/another[3626]
YKR021W ALY1 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr11:478877-481624 478877-481624 99.0% 107.37 104.43 86.05 66.56 83.84 95.61 105.90 76.30 89.72 0.39 0.31 0.37 0.23 0.66 Covered/w/another[3626]
YKR022C NTR2 "Essential protein that forms a dimer with Ntr1p; also forms a trimer, with Ntr2p and the DExD/H-box RNA helicase Prp43p, that is involved in spliceosome disassembly" Verified chr11:481814-482782 481814-482782 99.4% 150.48 166.05 131.80 127.65 157.74 74.72 158.26 129.72 116.23 0.58 0.53 0.48 -0.16 -0.36 Covered/w/another[3626]
YKR023W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr11:483062-484654 483062-484654 98.4% 97.00 97.64 99.56 86.15 102.11 65.09 97.32 92.86 83.60 0.36 0.38 0.35 -0.15 0.24 Matched[3627]
YKR024C DBP7 Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis Verified chr11:484787-487015 484787-487015 99.1% 100.54 61.14 58.87 52.08 8.15 4.98 80.84 55.48 6.57 0.30 0.23 0.03 -3.08 -3.16 Matched[3628]
YKR025W RPC37 RNA polymerase III subunit C37 Verified chr11:487413-488261 487413-488261 98.1% 237.71 171.68 180.08 146.47 55.22 43.22 204.69 163.27 49.22 0.76 0.66 0.20 -1.73 -0.70 Matched[3629]
YKR026C GCN3 "Alpha subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a positive regulator of GCN4 expression" Verified chr11:488381-489298 488381-489298 99.2% 314.17 271.33 294.40 246.06 123.03 73.60 292.75 270.23 98.32 1.08 1.10 0.41 -1.46 -1.31 Matched[3630]
YKR027W BCH2 "Member of the Chs5p-Arf1p-binding proteins (ChAPs), a group of 4 related, interacting proteins (Bch1p, Fmp50p, Bud7p, Chs6p) that mediate export of specific cargo proteins, including chitin synthase Chs3p, from the Golgi to plasma membrane" Verified chr11:491007-493304 491007-493304 98.9% 70.41 81.41 59.40 56.76 61.61 49.28 75.91 58.08 55.44 0.28 0.24 0.23 -0.07 -0.02 Matched[3631]
YKR028W SAP190 "Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap155p, and Sap185p" Verified chr11:493900-497196 493900-497196 98.7% 208.46 200.77 183.86 155.27 112.84 117.14 204.61 169.56 114.99 0.76 0.69 0.48 -0.56 0.26 Matched[3632]
YKR029C SET3 Defining member of the SET3 histone deacetylase complex which is a meiosis-specific repressor of sporulation genes; necessary for efficient transcription by RNAPII; one of two yeast proteins that contains both SET and PHD domains Verified chr11:497220-499475 497220-499475 99.3% 95.54 98.66 79.46 80.80 81.25 54.46 97.10 80.13 67.86 0.36 0.33 0.28 -0.24 0.00 Matched[3633]
YKR030W GMH1 "Golgi membrane protein of unknown function, interacts with Gea1p and Gea2p; required for localization of Gea2p; computational analysis suggests a possible role in either cell wall synthesis or protein-vacuolar targeting" Verified chr11:499924-500745 499924-500745 99.1% 169.47 197.72 217.37 207.54 256.66 125.26 183.60 212.45 190.96 0.68 0.86 0.79 -0.15 -0.14 Covered[3634]
YKR031C SPO14 "Phospholipase D, catalyzes the hydrolysis of phosphatidylcholine, producing choline and phosphatidic acid; involved in Sec14p-independent secretion; required for meiosis and spore formation; differently regulated in secretion and meiosis" Verified chr11:500986-506037 500986-506037 99.2% 84.58 98.94 74.60 75.80 67.82 99.14 91.76 75.20 83.48 0.34 0.31 0.35 0.15 0.36 Frag>80[3635]
YKR032W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr11:506159-506473 506159-506473 99.1% 0.00 3.20 0.00 0.00 0.00 3.20 1.60 0.00 1.60 0.01 0.00 0.01 Inf 0.11
YKR034W DAL80 "Negative regulator of genes in multiple nitrogen degradation pathways; expression is regulated by nitrogen levels and by Gln3p; member of the GATA-binding family, forms homodimers and heterodimers with Deh1p" Verified chr11:506540-507349 506540-507349 98.6% 3.76 3.76 3.76 2.51 2.51 7.52 3.76 3.13 5.01 0.01 0.01 0.02 0.68 0.46
YKR033C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene DAL80" Dubious chr11:506521-506946 506521-506946 98.5% 4.76 0.00 4.76 0.00 4.76 7.15 2.38 2.38 5.96 0.01 0.01 0.02 1.32 -0.16
YKR035W-A DID2 "Class E protein of the vacuolar protein-sorting (Vps) pathway, associates reversibly with the late endosome, has human ortholog that may be altered in breast tumors" Verified chr11:507581-508195 507581-508195 98.2% 323.05 286.60 303.17 324.70 447.30 278.32 304.83 313.94 362.81 1.13 1.27 1.50 0.21 -0.18 Matched[3636]
YKR035C OPI8 "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene DID2/YKR035W-A" Dubious chr11:507562-508203 507562-508203 98.2% 318.86 290.30 299.82 325.20 452.11 282.37 304.58 312.51 367.24 1.12 1.27 1.52 0.23 -0.36 Matched[3636]
YKR036C CAF4 "WD40 repeat-containing protein associated with the CCR4-NOT complex, interacts in a Ccr4p-dependent manner with Ssn2p; also interacts with Fis1p, Mdv1p and Dnm1p and plays a role in mitochondrial fission" Verified chr11:508344-510275 508344-510275 99.2% 104.88 117.40 89.74 78.79 54.26 48.52 111.14 84.27 51.39 0.41 0.34 0.21 -0.71 -0.49 Matched[3637]
YKR037C SPC34 "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; also localized to nuclear side of spindle pole body" Verified chr11:510552-511439 510552-511439 99.1% 107.91 114.72 86.33 87.46 147.66 117.00 111.32 86.89 132.33 0.41 0.35 0.55 0.61 0.53 Matched[3638]
YKR038C KAE1 "Putative glycoprotease proposed to be in transcription as a component of the EKC protein complex with Bud32p, Cgi121p, Pcc1p, and Gon7p; also identified as a component of the KEOPS protein complex" Verified chr11:511641-512801 511641-512801 99.0% 202.75 196.66 221.02 163.59 158.37 115.73 199.70 192.31 137.05 0.74 0.78 0.57 -0.49 0.04 Matched[3639]
YKR039W GAP1 General amino acid permease; localization to the plasma membrane is regulated by nitrogen source Verified chr11:514705-516513 514705-516513 98.7% 147.24 123.16 227.29 205.46 89.01 80.06 135.20 216.38 84.53 0.50 0.88 0.35 -1.36 -0.95 Matched[3641]
YKR041W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus Uncharacterized chr11:517840-518592 517840-518592 97.9% 36.61 24.41 17.63 13.56 12.20 9.49 30.51 15.59 10.85 0.11 0.06 0.04 -0.52 -0.24 Matched[3643]
YKR040C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YKR041W" Dubious chr11:517705-518208 517705-518208 95.4% 37.43 33.27 16.63 12.48 14.55 16.63 35.35 14.55 15.59 0.13 0.06 0.06 0.10 0.15 Matched[3643]
YKR042W UTH1 "Mitochondrial outer membrane and cell wall localized SUN family member required for mitochondrial autophagy; involved in the oxidative stress response, life span during starvation, mitochondrial biogenesis, and cell death" Verified chr11:519169-520266 519169-520266 98.8% 3904.00 3783.26 3868.98 3407.24 3931.65 3185.13 3843.63 3638.11 3558.39 14.19 14.77 14.74 -0.03 -0.72 Matched[3644]
YKR043C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus Uncharacterized chr11:520539-521354 520539-521354 98.9% 843.52 694.88 772.91 626.75 200.66 163.50 769.20 699.83 182.08 2.84 2.84 0.75 -1.94 -1.21 Matched[3645]
YKR044W UIP5 "Protein of unknown function that interacts with Ulp1p, a Ubl (ubiquitin-like protein)-specific protease for Smt3p protein conjugates" Verified chr11:521657-522988 521657-522988 98.6% 184.27 156.10 121.83 86.04 70.05 42.64 170.18 103.94 56.35 0.63 0.42 0.23 -0.88 -1.16 Matched[3646]
YKR045C Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm Uncharacterized chr11:523060-523611 523060-523611 98.4% 88.37 99.42 79.17 69.96 73.64 66.28 93.89 74.56 69.96 0.35 0.30 0.29 -0.09 0.22 Covered/w/another[3646]
YKR046C PET10 Protein of unknown function that co-purifies with lipid particles; expression pattern suggests a role in respiratory growth; computational analysis of large-scale protein-protein interaction data suggests a role in ATP/ADP exchange Verified chr11:523865-524716 523865-524716 98.5% 463.58 642.34 524.36 494.56 784.15 398.03 552.96 509.46 591.09 2.04 2.07 2.45 0.21 0.47 Matched[3647]
YKR047W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene NAP1" Dubious chr11:524899-525204 524899-525204 98.4% 744.08 700.90 744.08 581.31 916.82 647.75 722.49 662.70 782.28 2.67 2.69 3.24 0.24 0.44
YKR048C NAP1 Protein that interacts with mitotic cyclin Clb2p; required for the regulation of microtubule dynamics during mitosis; controls bud morphogenesis; involved in the transport of H2A and H2B histones to the nucleus Verified chr11:525029-526282 525029-526282 98.8% 647.30 590.80 641.65 622.28 808.72 735.27 619.05 631.96 771.99 2.29 2.57 3.20 0.29 0.65 Matched[3648]
YKR049C FMP46 "Putative redox protein containing a thioredoxin fold; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr11:526472-526873 526472-526873 98.8% 163.71 214.08 183.86 166.23 1125.83 798.40 188.90 175.04 962.12 0.70 0.71 3.99 2.46 2.05 Covered/w/another[3649]
YKR050W TRK2 Component of the Trk1p-Trk2p potassium transport system Verified chr11:527457-530126 527457-530126 98.8% 81.16 84.96 84.58 57.65 77.75 73.58 83.06 71.11 75.66 0.31 0.29 0.31 0.09 0.79 Covered/w/another[3649]
YKR051W Putative protein of unknown function Uncharacterized chr11:530588-531844 530588-531844 99.0% 149.45 184.81 177.58 163.11 217.75 134.99 167.13 170.34 176.37 0.62 0.69 0.73 0.05 0.32 Covered/w/another[3649]
YKR052C MRS4 "Mitochondrial iron transporter of the mitochondrial carrier family (MCF), very similar to and functionally redundant with Mrs3p; functions under low-iron conditions; may transport other cations in addition to iron" Verified chr11:532192-533106 532192-533106 98.8% 97.34 90.70 128.31 87.39 396.00 301.98 94.02 107.85 348.99 0.35 0.44 1.45 1.69 1.43 Covered/w/another[3649]
YKR053C YSR3 "Dihydrosphingosine 1-phosphate phosphatase, membrane protein involved in sphingolipid metabolism; has similarity to Lcb3p" Verified chr11:533709-534923 533709-534923 99.0% 75.68 65.70 70.69 44.08 58.21 30.77 70.69 57.38 44.49 0.26 0.23 0.18 -0.37 -0.02 Covered/w/another[3649]
YKR054C DYN1 "Cytoplasmic heavy chain dynein, microtubule motor protein, required for anaphase spindle elongation; involved in spindle assembly, chromosome movement, and spindle orientation during cell division, targeted to microtubule tips by Pac1p" Verified chr11:535289-547567 535289-547567 99.2% 34.63 42.02 29.05 27.24 17.89 27.82 38.32 28.15 22.85 0.14 0.11 0.09 -0.30 0.53 Frag<80[3650]
YKR055W RHO4 "Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely to be involved in the establishment of cell polarity" Verified chr11:547858-548733 547858-548733 98.7% 76.32 78.63 67.07 83.26 148.01 91.35 77.48 75.16 119.68 0.29 0.31 0.50 0.67 0.94 Matched[3651]
YKR056W TRM2 "tRNA methyltransferase, 5-methylates the uridine residue at position 54 of tRNAs and may also have a role in tRNA stabilization or maturation; endo-exonuclease with a role in DNA repair" Verified chr11:549090-551009 549090-551009 98.8% 153.98 90.70 75.41 56.95 11.07 3.16 122.34 66.18 7.12 0.45 0.27 0.03 -3.22 -2.99 Frag>80[3652]
YKR057W RPS21A Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Bp and has similarity to rat S21 ribosomal protein Verified chr11:551299-551884 551299-551322,551645-551884 82.1% 7480.10 5832.72 6709.48 6063.45 1601.23 1555.09 6656.41 6386.46 1578.16 24.57 25.92 6.54 -2.02 -2.86 Matched[3653]
YKR058W GLG1 "Self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside; similar to mammalian glycogenin" Verified chr11:552412-554262 552412-554262 98.8% 104.48 216.08 206.78 234.68 367.06 327.67 160.28 220.73 347.37 0.59 0.90 1.44 0.65 1.19 Matched[3654]
YKR059W TIF1 "Translation initiation factor eIF4A, identical to Tif2p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G" Verified chr11:554629-555816 554629-555816 6.1% 3013.82 2101.38 2447.00 2723.50 1188.94 1064.52 2557.60 2585.25 1126.73 9.44 10.49 4.67 -1.20 -1.97 Frag<80[3655,3656,3657,3658]
YKR060W UTP30 "Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data" Verified chr11:556160-556984 556160-556984 98.8% 154.64 103.09 106.78 71.18 20.86 29.46 128.87 88.98 25.16 0.48 0.36 0.10 -1.82 -2.00 Covered/w/another[3659]
YKR061W KTR2 Mannosyltransferase involved in N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family Verified chr11:557319-558596 557319-558596 98.8% 87.92 106.93 72.08 53.86 91.88 45.94 97.43 62.97 68.91 0.36 0.26 0.29 0.13 0.34 Covered/w/another[3659]
YKR062W TFA2 "TFIIE small subunit, involved in RNA polymerase II transcription initiation" Verified chr11:559308-560294 559308-560294 98.5% 232.44 221.13 238.61 226.27 280.78 233.47 226.78 232.44 257.12 0.84 0.94 1.07 0.15 0.06 Matched[3660]
YKR063C LAS1 Essential nuclear protein possibly involved in bud formation and morphogenesis; mutants require the SSD1-v allele for viability Verified chr11:560431-561939 560431-561939 99.5% 137.89 124.57 96.59 77.27 25.31 13.99 131.23 86.93 19.65 0.48 0.35 0.08 -2.15 -1.91 Matched[3661]
YKR064W OAF3 "Zinc cluster protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr11:562189-564780 562189-564780 98.9% 80.33 77.21 65.52 56.94 54.99 56.55 78.77 61.23 55.77 0.29 0.25 0.23 -0.13 0.24 Matched[3662]
YKR065C PAM17 "Presequence translocase-associated motor subunit, required for stable complex formation between cochaperones Pam16p and Pam18p, promotes association of Pam16p-Pam18p with the presequence translocase" Verified chr11:564941-565534 564941-565534 98.4% 437.89 431.05 496.04 431.05 514.86 424.20 434.47 463.54 469.53 1.60 1.88 1.95 0.02 0.17 Matched[3663]
YKR066C CCP1 "Mitochondrial cytochrome-c peroxidase; degrades reactive oxygen species in mitochondria, involved in the response to oxidative stress" Verified chr11:565755-566840 565755-566840 98.6% 451.21 679.15 554.90 572.65 1648.83 1549.80 565.18 563.78 1599.31 2.09 2.29 6.63 1.50 1.46 Matched[3664]
YKR067W GPT2 Glycerol-3-phosphate/dihydroxyacetone phosphate dual substrate-specific sn-1 acyltransferase located in lipid particles and the ER; involved in the stepwise acylation of glycerol-3-phosphate and dihydroxyacetone in lipid biosynthesis Verified chr11:567560-569791 567560-569791 98.8% 138.72 182.24 220.32 247.97 663.22 533.11 160.48 234.14 598.16 0.59 0.95 2.48 1.35 1.43 Frag>80[3665,3666]
YKR068C BET3 Hydrophilic protein that acts in conjunction with SNARE proteins in targeting and fusion of ER to Golgi transport vesicles; component of the TRAPP (transport protein particle) complex Verified chr11:569970-570551 569970-570551 99.4% 292.24 349.30 318.18 281.86 335.47 186.76 320.77 300.02 261.11 1.18 1.22 1.08 -0.20 -0.08 Matched[3667]
YKR069W MET1 "S-adenosyl-L-methionine uroporphyrinogen III transmethylase, involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis" Verified chr11:571254-573035 571254-573035 98.6% 50.08 75.70 45.53 43.25 49.52 37.56 62.89 44.39 43.54 0.23 0.18 0.18 -0.03 0.34 Matched[3668]
YKR070W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr11:573216-574274 573216-574274 98.7% 184.72 189.50 187.59 196.20 268.94 192.38 187.11 191.90 230.66 0.69 0.78 0.96 0.27 0.32 Matched[3669]
YKR071C DRE2 Protein of unknown function; mutation displays synthetic lethal interaction with the pol3-13 allele of CDC2 Verified chr11:574576-575622 574576-575622 99.2% 281.27 271.63 238.88 211.91 262.96 239.85 276.45 225.40 251.40 1.02 0.91 1.04 0.16 0.31 Frag<80[3670]
YKR072C SIS2 Negative regulatory subunit of the protein phosphatase 1 Ppz1p; involved in ion homeostasis and cell cycle progression Verified chr11:576077-577765 576077-577765 97.1% 231.13 216.49 210.39 181.73 148.80 146.36 223.81 196.06 147.58 0.83 0.80 0.61 -0.41 0.27 Matched[3671]
YKR073C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr11:577829-578149 577829-578149 98.3% 19.02 31.70 41.21 25.36 22.19 34.87 25.36 33.28 28.53 0.09 0.14 0.12 -0.22 0.59 Overlap[3671]
YKR074W Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm Uncharacterized chr11:578851-579318 578851-579318 98.9% 535.78 449.37 527.14 542.26 1289.77 758.30 492.57 534.70 1024.03 1.82 2.17 4.24 0.94 0.20 Matched[3672]
YKR075W-A "Dubious open reading frame unlikely to encode a protein; completely overlaps the uncharacterized gene YKR075W; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr11:579854-580123 579854-580123 99.2% 70.95 138.17 37.34 56.01 11.20 3.73 104.56 46.68 7.47 0.39 0.19 0.03 -2.64 NaN Matched[3674]
YKR075C Protein of unknown function; similar to YOR062Cp and Reg1p; expression regulated by glucose and Rgt1p; GFP-fusion protein is induced in response to the DNA-damaging agent MMS Uncharacterized chr11:579469-580392 579469-580392 98.9% 84.24 146.60 56.89 56.89 25.16 21.88 115.42 56.89 23.52 0.43 0.23 0.10 -1.27 -0.70 Frag>80[3672,3673,3674]
YKR076W ECM4 Omega class glutathione transferase; not essential; similar to Ygr154cp; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Verified chr11:581925-583037 581925-583037 98.7% 59.16 73.72 87.37 85.55 316.72 285.78 66.44 86.46 301.25 0.25 0.35 1.25 1.80 2.16 Matched[3676]
YKR077W "Putative transcriptional activator, identified by high-throughput two-hybrid experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YKR077W is not an essential gene" Uncharacterized chr11:583295-584386 583295-584386 99.2% 132.03 159.72 130.18 103.40 77.55 54.47 145.87 116.79 66.01 0.54 0.47 0.27 -0.82 -0.02 Matched[3677]
YKR078W "Cytoplasmic protein of unknown function, has similarity to Vps5p; potential Cdc28p substrate; contains a Phox homology (PX) domain and specifically binds phosphatidylinositol 3-phosphate (PtdIns-3-P)" Verified chr11:584594-586351 584594-586351 98.8% 73.72 66.81 60.47 59.32 56.44 42.62 70.26 59.90 49.53 0.26 0.24 0.21 -0.27 0.15 Matched[3678]
YKR079C TRZ1 "tRNase Z, involved in RNA processing, has two putative nucleotide triphosphate-binding motifs (P-loop) and a conserved histidine motif, homolog of the human candidate prostate cancer susceptibility gene ELAC2" Verified chr11:586431-588947 586431-588947 99.3% 104.45 83.64 76.04 60.83 14.41 6.00 94.05 68.43 10.20 0.35 0.28 0.04 -2.75 -2.38 Frag>80[3679]
YKR080W MTD1 "NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase, plays a catalytic role in oxidation of cytoplasmic one-carbon units; expression is regulated by Bas1p and Bas2p, repressed by adenine, and may be induced by inositol and choline" Verified chr11:590037-590999 590037-590999 98.7% 1320.13 1128.68 1361.15 921.46 325.04 146.21 1224.40 1141.30 235.62 4.52 4.63 0.98 -2.28 -2.46 Matched[3680]
YKR081C RPF2 Essential protein involved in the processing of pre-rRNA and the assembly of the 60S ribosomal subunit; interacts with ribosomal protein L11; localizes predominantly to the nucleolus; constituent of 66S pre-ribosomal particles Verified chr11:591148-592182 591148-592182 99.4% 332.56 164.34 211.98 168.23 18.48 0.97 248.45 190.11 9.72 0.92 0.77 0.04 -4.29 -4.06 Matched[3681]
YKR082W NUP133 "Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), localizes to both sides of the NPC, required to establish a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p" Verified chr11:592467-595940 592467-595940 99.1% 141.77 115.04 114.17 112.72 61.30 49.97 128.40 113.44 55.63 0.47 0.46 0.23 -1.03 -0.52 Matched[3682]
YKR083C DAD2 "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis" Verified chr11:596063-596464 596063-596464 99.7% 149.66 174.60 199.54 142.17 169.61 117.23 162.13 170.86 143.42 0.60 0.69 0.59 -0.25 -0.49 Covered/w/another[3682]
YKR084C HBS1 "GTP binding protein with sequence similarity to the elongation factor class of G proteins, EF-1alpha and Sup35p; associates with Dom34p, and shares a similar genetic relationship with genes that encode ribosomal protein components" Verified chr11:596697-598532 596697-598532 99.2% 186.08 163.02 163.02 165.22 149.85 133.93 174.55 164.12 141.89 0.64 0.67 0.59 -0.21 0.17 Matched[3683]
YKR085C MRPL20 Mitochondrial ribosomal protein of the large subunit Verified chr11:598736-599323 598736-599323 99.1% 458.30 339.87 435.99 382.78 351.88 180.23 399.08 409.38 266.06 1.47 1.66 1.10 -0.62 -1.02 Matched[3684]
YKR086W PRP16 "RNA helicase in the DEAH-box family involved in the second catalytic step of splicing, exhibits ATP-dependent RNA unwinding activity" Verified chr11:599499-602714 599499-602714 98.7% 83.76 81.87 63.61 51.01 29.91 20.78 82.81 57.31 25.35 0.31 0.23 0.11 -1.18 -0.90 Matched[3685]
YKR087C OMA1 "Metalloendopeptidase of the mitochondrial inner membrane, involved in turnover of membrane-embedded proteins; member of a family of predicted membrane-bound metallopeptidases in prokaryotes and higher eukaryotes" Verified chr11:602837-603874 602837-603874 99.2% 144.76 131.16 132.13 106.87 177.79 88.41 137.96 119.50 133.10 0.51 0.49 0.55 0.16 0.11 Matched[3686]
YKR088C TVP38 Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern Verified chr11:604047-605060 604047-605060 99.0% 246.97 287.80 245.98 225.06 257.93 171.29 267.39 235.52 214.61 0.99 0.96 0.89 -0.13 -0.09 Matched[3687]
YKR089C TGL4 Triacylglycerol lipase involved in triacylglycerol mobilization and degradation; found in lipid particles; potential Cdc28p substrate Verified chr11:605275-608007 605275-608007 98.9% 193.51 238.65 256.78 241.61 305.61 269.73 216.08 249.19 287.67 0.80 1.01 1.19 0.21 0.44 Frag>80[3688,3689]
YKR090W PXL1 "LIM domain-containing protein that localizes to sites of polarized growth, required for selection and/or maintenance of polarized growth sites, may modulate signaling by the GTPases Cdc42p and Rho1p; has similarity to metazoan paxillin" Verified chr11:608588-610708 608588-610708 98.6% 99.92 106.61 94.18 87.96 99.44 77.93 103.26 91.07 88.68 0.38 0.37 0.37 -0.04 0.42 Matched[3690]
YKR091W SRL3 "Cytoplasmic protein that, when overexpressed, suppresses the lethality of a rad53 null mutation; potential Cdc28p substrate" Verified chr11:611167-611907 611167-611907 98.8% 75.15 154.40 110.67 118.87 654.48 427.67 114.77 114.77 541.08 0.42 0.47 2.24 2.24 1.80 Matched[3691]
YKR092C SRP40 "Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140" Verified chr11:612307-613527 612307-613527 96.4% 558.79 388.10 372.81 279.40 90.87 45.86 473.44 326.10 68.36 1.75 1.32 0.28 -2.25 -1.80 Matched[3692]
YKR093W PTR2 "Integral membrane peptide transporter, mediates transport of di- and tri-peptides; conserved protein that contains 12 transmembrane domains; PTR2 expression is regulated by the N-end rule pathway via repression by Cup9p" Verified chr11:615372-617177 615372-617177 99.0% 392.51 715.68 480.29 582.05 230.92 253.84 554.10 531.17 242.38 2.05 2.16 1.00 -1.13 -0.86 Matched[3693]
YKR094C RPL40B "Fusion protein, identical to Rpl40Ap, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes" Verified chr11:617638-618392 617638-618016,618385-618392 49.7% 8206.28 6448.54 6781.36 6063.71 1284.51 712.46 7327.41 6422.54 998.48 27.05 26.07 4.14 -2.69 -0.10 Matched[3695]
YKR095W MLP1 "Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the nuclear interior; involved with Tel1p in telomere length control; involved with Pml1p and Pml39p in nuclear retention of unspliced mRNAs" Verified chr11:619447-625074 619447-625074 98.5% 241.47 234.25 196.74 190.07 111.45 143.37 237.86 193.41 127.41 0.88 0.79 0.53 -0.60 0.11 Matched[3696]
YKR095W-A PCC1 "Proposed transcription factor involved in the expression of genes regulated by alpha-factor and galactose; component of the EKC/KEOPS protein complex with Kae1p, Gon7p, Bud32p, and Cgi121p; related to human cancer-testis antigens" Verified chr11:625506-625847 625506-625543,625619-625847 98.7% 197.34 155.60 159.39 129.03 185.96 98.67 176.47 144.21 142.31 0.65 0.59 0.59 -0.02 NaN Covered/w/another[3697]
YKR096W "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; predicted to contain a PINc (PilT N terminus) domain" Verified chr11:626435-630022 626435-630022 98.8% 87.16 92.24 91.96 97.60 110.57 124.96 89.70 94.78 117.77 0.33 0.38 0.49 0.31 0.94 Covered/w/another[3697]
YKR097W PCK1 "Phosphoenolpyruvate carboxykinase, key enzyme in gluconeogenesis, catalyzes early reaction in carbohydrate biosynthesis, glucose represses transcription and accelerates mRNA degradation, regulated by Mcm1p and Cat8p, located in the cytosol" Verified chr11:630790-632439 630790-632439 98.9% 14.70 14.09 11.03 7.35 26.34 26.96 14.40 9.19 26.65 0.05 0.04 0.11 1.54 1.20 Frag<80[3698,3699]
YKR098C UBP11 Ubiquitin-specific protease that cleaves ubiquitin from ubiquitinated proteins Verified chr11:632664-634817 632664-634817 99.2% 68.34 111.40 105.31 93.14 98.76 78.17 89.87 99.23 88.46 0.33 0.40 0.37 -0.17 0.12 Matched[3700]
YKR099W BAS1 Myb-related transcription factor involved in regulating basal and induced expression of genes of the purine and histidine biosynthesis pathways; also involved in regulation of meiotic recombination at specific genes Verified chr11:635489-637924 635489-637924 98.6% 89.56 102.47 54.98 34.16 7.91 14.16 96.01 44.57 11.04 0.35 0.18 0.05 -2.01 -2.18 Matched[3701]
YKR100C SKG1 Transmembrane protein with a role in cell wall polymer composition; localizes on the inner surface of the plasma membrane at the bud and in the daughter cell Verified chr11:638539-639606 638539-639606 99.1% 245.65 236.20 268.33 239.98 328.79 259.82 240.93 254.15 294.31 0.89 1.03 1.22 0.21 0.57 Matched[3702]
YKR101W SIR1 "Protein involved in repression of transcription at the silent mating-type loci HML and HMR; recruitment to silent chromatin requires interactions with Orc1p and with Sir4p, through a common Sir1p domain; binds to centromeric chromatin" Verified chr11:640106-642142 640106-642142 98.7% 45.25 48.23 39.28 27.35 74.59 47.24 46.74 33.32 60.91 0.17 0.14 0.25 0.87 1.18 Matched[3703]
YKR102W FLO10 "Lectin-like protein with similarity to Flo1p, thought to be involved in flocculation" Verified chr11:645994-649503 645994-649503 76.3% 24.65 32.49 17.18 14.94 12.32 14.19 28.57 16.06 13.26 0.11 0.07 0.05 -0.28 -0.20
YKR103W NFT1 Putative transporter of the multidrug resistance-associated protein (MRP) subfamily; adjacent ORFs YKR103W and YKR104W are merged in different strain backgrounds. Verified chr11:652718-656374 652718-656374 98.9% 17.69 28.75 14.37 10.78 12.99 10.23 23.22 12.58 11.61 0.09 0.05 0.05 -0.12 0.15 Overlap[3704]
YKR104W Putative transporter of the multidrug resistance-associated protein (MRP) subfamily; contains a stop codon in S288C; adjacent ORFs YKR103W and YKR104W are merged in different strain backgrounds Verified chr11:656474-657394 656474-657394 98.9% 36.21 50.48 18.65 13.17 6.58 12.07 43.35 15.91 9.33 0.16 0.06 0.04 -0.77 0.32
YKR105C Putative transporter of the Major Facilitator Superfamily (MFS) Uncharacterized chr11:658354-660102 658354-660102 3.0% 37.94 18.97 0.00 37.94 0.00 0.00 28.46 18.97 0.00 0.11 0.08 0.00 -Inf 0.10
YKR106W Protein of unconfirmed function; displays a topology characteristic of the Major Facilitators Superfamily of membrane proteins; coding sequence 98% identical to that of YCL073C Uncharacterized chr11:661080-662927 661080-662927 7.4% 7.27 7.27 7.27 36.35 36.35 14.54 7.27 21.81 25.45 0.03 0.09 0.11 0.22 0.99
YLL067W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps YLL067C" Dubious chr12:843-1325 843-1325 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YLL067C Putative protein of unknown function with similarity to helicases Uncharacterized chr12:585-4301 585-3915,4015-4301 0.3% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN -0.19
YLL066W-B "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Uncharacterized chr12:5605-5775 5605-5775 23.1% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN NaN
YLL066W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the uncharacterized ORF YLL066C" Dubious chr12:6486-6968 6486-6968 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YLL066C Putative protein of unknown function with similarity to helicases; YLL066C is not an essential gene Uncharacterized chr12:6120-9836 6120-9450,9550-9836 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.32
YLL065W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps chromosome XII telomeric element core sequences" Dubious chr12:11726-12076 11726-12076 1.8% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN -0.53
YLL064C Hypothetical protein Uncharacterized chr12:13083-13445 13083-13445 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.03
YLL063C AYT1 "Acetyltransferase; catalyzes trichothecene 3-O-acetylation, suggesting a possible role in trichothecene biosynthesis" Verified chr12:14648-16072 14648-16072 98.8% 45.46 53.98 50.43 44.04 36.22 26.28 49.72 47.23 31.25 0.18 0.19 0.13 -0.60 0.07 Matched[3707]
YLL062C MHT1 "S-methylmethionine-homocysteine methyltransferase, functions along with Sam4p in the conversion of S-adenosylmethionine (AdoMet) to methionine to control the methionine/AdoMet ratio" Verified chr12:16639-17613 16639-17613 99.0% 30.04 43.50 29.00 27.97 23.82 15.54 36.77 28.49 19.68 0.14 0.12 0.08 -0.53 0.12 Covered/w/another[3708]
YLL061W MMP1 "High-affinity S-methylmethionine permease, required for utilization of S-methylmethionine as a sulfur source; has similarity to S-adenosylmethionine permease Sam3p" Verified chr12:17956-19707 17956-19707 98.8% 36.38 64.10 48.51 50.24 40.43 43.31 50.24 49.38 41.87 0.19 0.20 0.17 -0.24 0.85 Covered/w/another[3708]
YLL060C GTT2 "Glutathione S-transferase capable of homodimerization; functional overlap with Gtt2p, Grx1p, and Grx2p" Verified chr12:21138-21839 21138-21839 98.9% 123.93 116.72 103.75 66.29 144.10 67.73 120.32 85.02 105.91 0.44 0.35 0.44 0.32 -0.12 Covered/w/another[3708]
YLL059C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr12:22474-22980 22474-22980 98.7% 19.99 25.98 15.99 8.00 4.00 15.99 22.99 11.99 9.99 0.08 0.05 0.04 -0.26 0.30 Covered/w/another[3708]
YLL058W "Putative protein of unknown function with similarity to Str2p, which is a cystathionine gamma-synthase important in sulfur metabolism; YLL058W is not an essential gene" Uncharacterized chr12:23569-25296 23569-25296 98.6% 62.22 104.49 79.24 79.83 106.25 102.72 83.35 79.54 104.49 0.31 0.32 0.43 0.39 0.66 Matched[3709]
YLL057C JLP1 "Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase, involved in sulfonate catabolism for use as a sulfur source, contains sequence that closely resembles a J domain (typified by the E. coli DnaJ protein)" Verified chr12:25756-26994 25756-26994 98.9% 22.04 15.51 26.94 12.24 29.39 20.41 18.77 19.59 24.90 0.07 0.08 0.10 0.35 0.76
YLL056C "Putative protein of unknown function, transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in pleiotropic drug resistance (PDR) phenomenon; YLL056C is not an essential gene" Uncharacterized chr12:27409-28305 27409-28305 99.0% 38.29 59.68 51.80 27.03 64.19 27.03 48.99 39.41 45.61 0.18 0.16 0.19 0.21 0.46 Covered/w/another[3710]
YLL055W YCT1 High-affinity cysteine-specific transporter with similarity to the Dal5p family of transporters; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YCT1 is not an essential gene Verified chr12:30109-31704 30109-31704 99.0% 79.09 108.20 84.15 61.37 111.36 74.66 93.64 72.76 93.01 0.35 0.30 0.39 0.35 0.74 Covered/w/another[3710]
YLL054C "Putative protein of unknown function with similarity to Pip2p, an oleate-specific transcriptional activator of peroxisome proliferation; YLL054C is not an essential gene" Uncharacterized chr12:32894-35203 32894-35203 99.0% 61.64 71.69 55.08 45.03 26.67 22.73 66.67 50.05 24.70 0.25 0.20 0.10 -1.02 -1.28 Covered/w/another[3711]
YLL053C Putative protein; in the Sigma 1278B strain background YLL053C is contiguous with AQY2 which encodes an aquaporin Uncharacterized chr12:35502-35960 35502-35960 98.5% 55.30 33.18 44.24 33.18 70.78 28.76 44.24 38.71 49.77 0.16 0.16 0.21 0.36 0.99 Covered/w/another[3711]
YLL052C AQY2 "Water channel that mediates the transport of water across cell membranes, only expressed in proliferating cells, controlled by osmotic signals, may be involved in freeze tolerance; disrupted by a stop codon in many S. cerevisiae strains" Verified chr12:35911-36360 35911-36360 98.4% 33.87 36.13 36.13 15.81 31.61 27.10 35.00 25.97 29.35 0.13 0.11 0.12 0.18 0.75 Covered/w/another[3711]
YLL051C FRE6 Putative ferric reductase with similarity to Fre2p; expression induced by low iron levels Verified chr12:37332-39470 37332-39470 98.9% 137.12 96.93 125.77 96.93 75.18 53.43 117.02 111.35 64.30 0.43 0.45 0.27 -0.79 0.06 Matched[3713]
YLL050C COF1 "Cofilin, promotes actin filament depolarization in a pH-dependent manner; binds both actin monomers and filaments and severs filaments , thought to be regulated by phosphorylation at SER4, ubiquitous and essential in eukaryotes" Verified chr12:39803-40413 39803-40220,40400-40413 98.7% 5304.15 5829.41 5632.44 5222.08 7946.85 5569.13 5566.78 5427.26 6757.99 20.55 22.03 28.00 0.32 -0.61 Matched[3714]
YLL049W LDB18 Protein of unknown function; null mutant shows a reduced affinity for the alcian blue dye suggesting a decreased net negative charge of the cell surface Verified chr12:40665-41204 40665-41204 98.9% 183.48 161.01 161.01 121.69 252.75 108.59 172.24 141.35 180.67 0.64 0.57 0.75 0.35 -0.44 Matched[3715]
YLL048C YBT1 Transporter of the ATP-binding cassette (ABC) family involved in bile acid transport; similar to mammalian bile transporters Verified chr12:41279-46264 41279-46264 99.0% 253.63 268.83 235.20 223.25 97.85 126.82 261.23 229.22 112.33 0.96 0.93 0.47 -1.03 -0.30 Frag>80[3715,3716,3717]
YLL047W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene RNP1" Dubious chr12:46671-47054 46671-47054 99.2% 26.26 18.38 10.50 2.63 36.76 70.90 22.32 6.56 53.83 0.08 0.03 0.22 3.04 0.08 Matched[3718]
YLL046C RNP1 Ribonucleoprotein that contains two RNA recognition motifs (RRM) Verified chr12:46713-47462 46713-47462 99.4% 18.77 17.43 8.05 5.36 22.79 49.61 18.10 6.70 36.20 0.07 0.03 0.15 2.43 1.39 Matched[3718]
YLL044W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; transcription of both YLL044W and the overlapping gene RPL8B is reduced in the gcr1 null mutant" Dubious chr12:48215-48661 48215-48661 46.8% 6896.72 5048.36 5946.27 5081.79 907.46 740.30 5972.54 5514.03 823.88 22.05 22.38 3.41 -2.74 -0.17 Matched[3719]
YLL045C RPL8B "Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Ap and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits" Verified chr12:47858-48628 47858-48628 46.0% 7716.10 5880.14 6351.12 5775.79 1167.57 786.84 6798.12 6063.45 977.20 25.10 24.61 4.05 -2.63 -2.50 Matched[3719]
YLL043W FPS1 "Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) family of channel proteins; involved in efflux of glycerol and in uptake of the trivalent metalloids arsenite and antimonite" Verified chr12:49937-51946 49937-51946 97.9% 316.64 330.87 332.39 314.61 254.12 190.59 323.75 323.50 222.36 1.20 1.31 0.92 -0.54 0.13 Matched[3721]
YLL042C ATG10 "E2-like conjugating enzyme that mediates formation of the Atg12p-Atg5p conjugate, which is a critical step in autophagy" Verified chr12:52086-52589 52086-52589 99.0% 22.04 32.06 26.05 22.04 28.05 8.01 27.05 24.04 18.03 0.10 0.10 0.07 -0.42 -0.40 Matched[3722]
YLL041C SDH2 "Iron-sulfur protein subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone" Verified chr12:53130-53930 53130-53930 99.0% 330.51 433.96 518.48 668.59 956.22 697.61 382.23 593.53 826.91 1.41 2.41 3.43 0.48 0.71 Matched[3723]
YLL040C VPS13 "Protein of unknown function; heterooligomeric or homooligomeric complex; peripherally associated with membranes; homologous to human COH1; involved in sporulation, vacuolar protein sorting and protein-Golgi retention" Verified chr12:54210-63644 54210-63644 99.2% 88.92 126.97 89.14 89.24 76.74 139.58 107.95 89.19 108.16 0.40 0.36 0.45 0.28 0.74 Frag>80[3724,3725,3726,3727]
YLL039C UBI4 "Ubiquitin, becomes conjugated to proteins, marking them for selective degradation via the ubiquitin-26S proteasome system; essential for the cellular stress response; encoded as a polyubiquitin precursor comprised of 5 head-to-tail repeats" Verified chr12:64061-65206 64061-65206 57.3% 575.60 875.58 793.35 904.51 15487.85 10861.75 725.59 848.93 13174.80 2.68 3.45 54.59 3.96 3.39 Frag>80[3727,3728,3729]
YLL038C ENT4 "Protein of unknown function, contains an N-terminal epsin-like domain" Verified chr12:65774-66517 65774-66517 99.0% 84.22 95.08 67.92 74.71 35.32 55.69 89.65 71.31 45.50 0.33 0.29 0.19 -0.65 -0.83 Matched[3730]
YLL037W Dubious open reading frame unlikely to encode a functional protein; overlaps 3' end of essential PRP19 gene encoding an RNA splicing factor Dubious chr12:66561-66941 66561-66941 99.1% 108.54 76.77 105.89 113.83 92.65 113.83 92.65 109.86 103.24 0.34 0.45 0.43 -0.09 0.47
YLL036C PRP19 "Splicing factor associated with the spliceosome; contains a U-box, a motif found in a class of ubiquitin ligases" Verified chr12:66744-68255 66744-68255 99.1% 147.46 148.13 150.13 138.12 109.43 122.11 147.79 144.12 115.77 0.55 0.59 0.48 -0.32 0.19 Matched[3731]
YLL035W GRC3 "Protein of unknown function, required for cell growth and possibly involved in rRNA processing; mRNA is cell cycle regulated" Verified chr12:68579-70477 68579-70477 98.8% 76.71 66.06 53.81 38.89 13.85 12.79 71.39 46.35 13.32 0.26 0.19 0.06 -1.80 -0.64 Covered/w/another[3732]
YLL034C RIX7 "Putative ATPase of the AAA family, required for export of pre-ribosomal large subunits from the nucleus; distributed between the nucleolus, nucleoplasm, and nuclear periphery depending on growth conditions" Verified chr12:70632-73145 70632-73145 99.1% 150.47 78.25 109.14 94.70 7.62 2.01 114.36 101.92 4.82 0.42 0.41 0.02 -4.40 -4.16 Covered/w/another[3732]
YLL033W Putative protein of unknown function; YLL033W is not an essential gene but mutant is defective in spore formation; null mutant displays increased levels of spontaneous Rad52 foci Uncharacterized chr12:73408-74100 73408-74100 98.9% 72.95 62.74 42.31 45.23 24.80 27.72 67.84 43.77 26.26 0.25 0.18 0.11 -0.74 -0.08 Matched[3733]
YLL032C "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLL032C is not an essential gene" Verified chr12:74269-76746 74269-76746 99.2% 79.75 72.02 59.00 54.52 51.67 52.08 75.88 56.76 51.88 0.28 0.23 0.21 -0.13 0.23 Matched[3734]
YLL031C GPI13 ER membrane localized phosphoryltransferase that adds phosphoethanolamine onto the third mannose residue of the glycosylphosphatidylinositol (GPI) anchor precursor; similar to human PIG-O protein Verified chr12:77151-80204 77151-80204 98.9% 184.37 173.78 153.92 178.74 107.91 115.52 179.07 166.33 111.71 0.66 0.68 0.46 -0.57 0.27 Matched[3735]
YLL030C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr12:80355-80696 80355-80696 98.9% 5.92 5.92 2.96 2.96 0.00 8.87 5.92 2.96 4.44 0.02 0.01 0.02 0.58 0.95 Overlap[3735]
YLL029W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLL029W is not an essential gene but mutant is defective in spore formation Uncharacterized chr12:81460-83709 81460-83709 98.5% 260.75 248.57 246.32 253.08 592.78 616.69 254.66 249.70 604.74 0.94 1.01 2.51 1.28 1.66 Matched[3737]
YLL028W TPO1 "Polyamine transporter that recognizes spermine, putrescine, and spermidine; catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH; phosphorylation enhances activity and sorting to the plasma membrane" Verified chr12:84803-86563 84803-86563 98.8% 329.48 197.23 266.23 261.06 599.17 954.53 263.36 263.64 776.85 0.97 1.07 3.22 1.56 2.00 Matched[3738]
YLL027W ISA1 "Mitochondrial matrix protein involved in biogenesis of the iron-sulfur (Fe/S) cluster of Fe/S proteins, isa1 deletion causes loss of mitochondrial DNA and respiratory deficiency; depletion reduces growth on nonfermentable carbon sources" Verified chr12:87402-88154 87402-88154 98.3% 270.09 421.34 302.50 232.28 256.58 167.45 345.71 267.39 212.02 1.28 1.09 0.88 -0.33 -0.41 Matched[3739]
YLL026W HSP104 "Heat shock protein that cooperates with Ydj1p (Hsp40) and Ssa1p (Hsp70) to refold and reactivate previously denatured, aggregated proteins; responsive to stresses including: heat, ethanol, and sodium arsenite; involved in [PSI+] propagation" Verified chr12:88622-91348 88622-91348 98.7% 582.47 1399.13 854.57 1128.52 18967.75 16392.90 990.80 991.54 17680.33 3.66 4.02 73.26 4.16 3.53 Frag>80[3740,3741,3742]
YLL025W Putative protein of unknown function; YLL025W is not an essential gene Uncharacterized chr12:94746-95120 94746-95120 47.7% 22.38 33.57 33.57 16.78 33.57 0.00 27.97 25.17 16.78 0.10 0.10 0.07 -0.58 1.05 Frag<80[3744,3745]
YLL024C SSA2 "ATP binding protein involved in protein folding and vacuolar import of proteins; member of heat shock protein 70 (HSP70) family; associated with the chaperonin-containing T-complex; present in the cytoplasm, vacuolar membrane and cell wall" Verified chr12:95565-97484 95565-97484 26.7% 5483.04 3639.14 4577.64 4610.74 26620.80 20598.41 4561.09 4594.19 23609.61 16.84 18.65 97.82 2.36 1.63 Frag<80[3744,3745,3746,3747,3748,3749,3750,3751]
YLL023C "Protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum" Verified chr12:97996-98835 97996-98835 98.4% 302.37 417.28 394.30 416.07 886.56 759.56 359.82 405.18 823.06 1.33 1.64 3.41 1.02 1.29 Frag>80[3751,3752,3753]
YLL022C HIF1 "Non-essential component of the HAT-B histone acetyltransferase complex (Hat1p-Hat2p-Hif1p), localized to the nucleus; has a role in telomeric silencing" Verified chr12:99043-100200 99043-100200 99.0% 142.21 92.48 113.42 115.16 48.86 29.66 117.34 114.29 39.26 0.43 0.46 0.16 -1.54 -1.08 Frag>80[3753,3754]
YLL021W SPA2 "Component of the polarisome, which functions in actin cytoskeletal organization during polarized growth; acts as a scaffold for Mkk1p and Mpk1p cell wall integrity signaling components; potential Cdc28p substrate" Verified chr12:100946-105346 100946-105346 97.8% 222.04 167.69 177.45 164.67 50.17 77.34 194.87 171.06 63.76 0.72 0.69 0.26 -1.42 -0.70 Matched[3755]
YLL020C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene KNS1" Dubious chr12:105555-105860 105555-105860 98.6% 172.35 172.35 172.35 178.98 490.54 394.42 172.35 175.67 442.48 0.64 0.71 1.83 1.33 1.30 Covered/w/another[3756]
YLL019W-A Dubious open reading frame unlikely to encode a protein; completely overlaps the verified gene KNS1 Dubious chr12:106907-106999 106907-106999 98.9% 119.57 119.57 152.17 152.17 282.61 423.91 119.57 152.17 353.26 0.44 0.62 1.46 1.22 NaN Covered/w/another[3756]
YLL019C KNS1 "Nonessential putative protein kinase of unknown cellular role; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues" Verified chr12:105685-107898 105685-107898 98.9% 157.57 189.08 190.91 186.34 343.46 397.81 173.33 188.63 370.63 0.64 0.77 1.54 0.97 1.35 Covered/w/another[3756]
YLL018C-A COX19 "Protein required for cytochrome c oxidase assembly, located in the cytosol and mitochondrial intermembrane space; putative copper metallochaperone that delivers copper to cytochrome c oxidase" Verified chr12:108675-108971 108675-108971 98.9% 125.99 166.86 160.05 125.99 146.42 173.67 146.42 143.02 160.05 0.54 0.58 0.66 0.16 0.80 Covered/w/another[3756]
YLL018C DPS1 "Cytoplasmic aspartyl-tRNA synthetase, homodimeric enzyme that catalyzes the specific aspartylation of tRNA(Asp); class II aminoacyl tRNA synthetase; binding to its own mRNA may confer autoregulation" Verified chr12:109901-111574 109901-111574 99.0% 1114.20 1223.45 1099.11 1121.44 584.87 607.20 1168.83 1110.28 596.03 4.31 4.51 2.47 -0.90 -0.27 Frag>80[3757,3758,3759]
YLL015W BPT1 "ABC type transmembrane transporter of MRP/CFTR family, found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p" Verified chr12:116431-121110 116431-121110 98.9% 102.86 96.38 97.89 85.14 84.71 80.82 99.62 91.52 82.76 0.37 0.37 0.34 -0.15 0.07
YLL014W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YLL014W is not an essential gene Uncharacterized chr12:121321-121647 121321-121647 99.1% 656.98 623.06 592.21 499.68 539.78 385.55 640.02 545.95 462.67 2.36 2.22 1.92 -0.24 -0.94 Covered/w/another[3762]
YLL013C PUF3 "Protein of the mitochondrial outer surface, links the Arp2/3 complex with the mitochore during anterograde mitochondrial movement; also binds to and promotes degradation of mRNAs for select nuclear-encoded mitochondrial proteins" Verified chr12:122074-124713 122074-124713 98.5% 286.15 274.62 293.08 307.31 111.15 158.46 280.38 300.19 134.81 1.04 1.22 0.56 -1.15 -0.41 Covered/w/another[3762]
YLL012W YEH1 "Steryl ester hydrolase, one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes" Verified chr12:125533-127254 125533-127254 98.7% 50.02 87.68 45.90 26.48 25.30 25.30 68.85 36.19 25.30 0.25 0.15 0.10 -0.52 -0.25 Matched[3763]
YLL011W SOF1 Essential protein required for biogenesis of 40S (small) ribosomal subunit; has similarity to the beta subunit of trimeric G-proteins and the splicing factor Prp4p Verified chr12:127522-128991 127522-128991 98.6% 178.61 146.19 127.58 121.37 14.48 19.31 162.40 124.47 16.90 0.60 0.51 0.07 -2.88 -3.65 Matched[3764]
YLL010C PSR1 "Plasma membrane associated protein phosphatase involved in the general stress response; required along with binding partner Whi2p for full activation of STRE-mediated gene expression, possibly through dephosphorylation of Msn2p" Verified chr12:129329-130612 129329-130612 98.4% 175.75 196.33 207.42 154.37 202.67 153.58 186.04 180.89 178.12 0.69 0.73 0.74 -0.02 0.20 Matched[3765]
YLL009C COX17 Copper metallochaperone that transfers copper to Sco1p and Cox11p for eventual delivery to cytochrome c oxidase Verified chr12:131204-131413 131204-131413 99.4% 747.01 742.22 713.49 703.91 1494.01 761.37 744.61 708.70 1127.69 2.75 2.88 4.67 0.67 0.13 Matched[3766]
YLL008W DRS1 "Nucleolar DEAD-box protein required for ribosome assembly and function, including synthesis of 60S ribosomal subunits; constituent of 66S pre-ribosomal particles" Verified chr12:131728-133986 131728-133986 98.2% 254.23 127.56 133.42 100.97 19.38 6.31 190.89 117.20 12.85 0.70 0.48 0.05 -3.19 -3.07 Covered/w/another[3767]
YLL007C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLL007C is not an essential gene Uncharacterized chr12:134301-136298 134301-136298 99.2% 67.63 53.49 51.48 51.98 48.95 42.90 60.56 51.73 45.92 0.22 0.21 0.19 -0.17 0.18 Covered/w/another[3767]
YLL006W-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr12:136344-136520 136344-136520 99.3% 5.69 22.75 0.00 5.69 0.00 5.69 14.22 2.84 2.84 0.05 0.01 0.01 0.00 NaN Overlap[3767]
YLL006W MMM1 "Mitochondrial outer membrane protein, component of the Mdm10-Mdm12-Mmm1 complex involved in import and assembly of outer membrane beta-barrel proteins" Verified chr12:136585-137865 136585-137865 98.9% 80.49 109.69 72.60 108.11 149.93 189.39 95.09 90.35 169.66 0.35 0.37 0.70 0.91 1.13 Covered[3768]
YLL005C SPO75 "Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensable for both nuclear divisions during meiosis" Verified chr12:137939-140545 137939-140545 99.0% 59.25 79.39 61.19 48.02 61.96 38.34 69.32 54.61 50.15 0.26 0.22 0.21 -0.12 0.15 Overlap[3768]
YLL004W ORC3 "Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing" Verified chr12:141072-142922 141072-142922 99.0% 79.70 67.14 63.87 49.67 54.59 30.57 73.42 56.77 42.58 0.27 0.23 0.18 -0.42 -0.36 Matched[3769]
YLL003W SFI1 "Centrin (Cdc31p)-binding protein required for spindle pole body (SPB) duplication, localizes to the half-bridge of the SPB, required for progression through G(2)-M transition, has similarity to Xenopus laevis XCAP-C" Verified chr12:143200-146040 143200-146040 98.7% 77.02 81.65 57.76 52.41 60.26 45.28 79.33 55.09 52.77 0.29 0.22 0.22 -0.06 0.05 Covered/w/another[3770]
YLL002W RTT109 "Histone acetyltransferase critical for cell survival in the presence of DNA damage during S phase, acetylates H3-K56; plays a role in regulation of Ty1 transposition" Verified chr12:146290-147600 146290-147600 98.8% 82.64 88.05 82.64 75.69 45.57 24.72 85.34 79.17 35.14 0.32 0.32 0.15 -1.17 -1.14 Covered/w/another[3770]
YLL001W DNM1 "Dynamin-related GTPase required for mitochondrial fission and the maintenance of mitochondrial morphology, assembles on the cytoplasmic face of mitochondrial tubules at sites at which division will occur; also participates in endocytosis" Verified chr12:147889-150162 147889-150162 98.8% 135.72 151.74 167.76 154.41 193.12 138.83 143.73 161.08 165.98 0.53 0.65 0.69 0.04 0.23 Frag>80[3771,3772]
YLR001C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YLR001C is not an essential gene" Uncharacterized chr12:151388-153976 151388-153976 99.1% 84.60 137.62 103.70 93.57 123.98 113.45 111.11 98.64 118.71 0.41 0.40 0.49 0.27 0.79 Matched[3773]
YLR002C NOC3 Protein that forms a nuclear complex with Noc2p that binds to 66S ribosomal precursors to mediate their intranuclear transport; also binds to chromatin to promote the association of DNA replication factors and replication initiation Verified chr12:154342-156333 154342-156333 99.1% 176.75 86.60 108.89 96.23 14.18 5.57 131.68 102.56 9.88 0.49 0.42 0.04 -3.38 -4.56 Matched[3774]
YLR003C Putative protein of unknown function that may participate in DNA replication; green fluorescent protein (GFP)-fusion protein is localized to the nucleus; YLR003C is not an essential gene Uncharacterized chr12:156854-157729 156854-157729 99.3% 271.33 134.51 174.75 141.41 28.74 17.25 202.92 158.08 22.99 0.75 0.64 0.10 -2.78 -2.64 Matched[3775]
YLR004C THI73 Putative plasma membrane permease proposed to be involved in carboxylic acid uptake and repressed by thiamine; substrate of Dbf2p/Mob1p kinase; transcription is altered if mitochondrial dysfunction occurs Verified chr12:157933-159504 157933-159504 98.8% 37.34 37.34 19.96 12.87 17.38 14.16 37.34 16.42 15.77 0.14 0.07 0.07 -0.06 0.08
YLR005W SSL1 "Component of the core form of RNA polymerase transcription factor TFIIH, which has both protein kinase and DNA-dependent ATPase/helicase activities and is essential for transcription and nucleotide excision repair; interacts with Tfb4p" Verified chr12:160048-161433 160048-161433 98.6% 144.83 152.87 130.93 113.37 188.71 151.41 148.85 122.15 170.06 0.55 0.50 0.70 0.48 0.64 Covered/w/another[3776]
YLR006C SSK1 "Cytoplasmic response regulator, part of a two-component signal transducer that mediates osmosensing via a phosphorelay mechanism; dephosphorylated form is degraded by the ubiquitin-proteasome system; potential Cdc28p substrate" Verified chr12:161754-163892 161754-163892 98.8% 122.98 134.80 144.26 122.51 203.39 193.93 128.89 133.39 198.66 0.48 0.54 0.82 0.57 0.88 Covered/w/another[3776]
YLR007W NSE1 Essential subunit of the Mms21-Smc5-Smc6 complex; nuclear protein required for DNA repair and growth Verified chr12:164391-165401 164391-165401 98.6% 108.31 139.40 85.25 88.25 103.30 47.14 123.86 86.75 75.22 0.46 0.35 0.31 -0.21 -0.99 Matched[3777]
YLR008C PAM18 "J-protein co-chaperone of the mitochondrial import motor associated with the presequence translocase, with Ssc1p, Tim44p, Mge1p, and Pam16p; stimulates ATPase activity of Ssc1p to drive mitochondrial import; activity is inhibited by Pam16p" Verified chr12:165576-166082 165576-166082 99.2% 429.57 316.21 375.87 342.06 186.94 161.09 372.89 358.97 174.01 1.38 1.46 0.72 -1.04 -0.90 Matched[3778]
YLR009W RLP24 "Essential protein with similarity to Rpl24Ap and Rpl24Bp, associated with pre-60S ribosomal subunits and required for ribosomal large subunit biogenesis" Verified chr12:166536-167135 166536-167135 98.1% 599.58 293.84 354.99 280.25 27.18 6.79 446.71 317.62 16.99 1.65 1.29 0.07 -4.22 -3.36 Matched[3779]
YLR010C TEN1 Protein that regulates telomeric length; protects telomeric ends in a complex with Cdc13p and Stn1p Verified chr12:167319-167801 167319-167801 99.4% 49.99 66.66 68.74 35.41 91.65 49.99 58.32 52.07 70.82 0.22 0.21 0.29 0.44 -0.27 Matched[3780]
YLR011W LOT6 FMN-dependent NAD(P)H:quinone reductase that may be involved in quinone detoxification; gene expression increases in cultures shifted to a lower temperature Verified chr12:169102-169677 169102-169677 98.4% 89.94 72.31 100.52 72.31 91.70 44.09 81.12 86.41 67.90 0.30 0.35 0.28 -0.35 0.20 Matched[3781]
YLR012C Putative protein of unknown function; YLR012C is not an essential gene Uncharacterized chr12:169981-170280 169981-170280 99.3% 3.36 3.36 0.00 3.36 10.07 16.79 3.36 1.68 13.43 0.01 0.01 0.06 3.00 2.00 Matched[3782]
YLR013W GAT3 Protein containing GATA family zinc finger motifs Verified chr12:171338-171763 171338-171763 98.5% 2.38 0.00 0.00 0.00 0.00 2.38 1.19 0.00 1.19 0.00 0.00 0.00 Inf 0.11
YLR014C PPR1 "Zinc finger transcription factor containing a Zn(2)-Cys(6) binuclear cluster domain, positively regulates transcription of genes involved in uracil biosynthesis; activity may be modulated by interaction with Tup1p" Verified chr12:172267-174981 172267-174981 99.1% 41.64 28.63 20.82 19.33 10.78 7.81 35.14 20.08 9.30 0.13 0.08 0.04 -1.11 -0.84 Frag<80[3783]
YLR015W BRE2 "Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; involved in telomere maintenance; similar to trithorax-group protein ASH2L" Verified chr12:175226-176743 175226-176743 98.4% 109.13 83.69 81.01 65.61 53.56 32.81 96.41 73.31 43.18 0.36 0.30 0.18 -0.76 -0.69 Covered/w/another[3784]
YLR016C PML1 "Subunit of the RES complex, which is required for nuclear retention of unspliced pre-mRNAs; acts in the same pathway as Pml39p and Mlp1p" Verified chr12:176801-177415 176801-177415 99.1% 178.84 146.02 137.82 129.61 137.82 100.08 162.43 133.72 118.95 0.60 0.54 0.49 -0.17 0.10 Covered/w/another[3784]
YLR017W MEU1 "Methylthioadenosine phosphorylase (MTAP), catalyzes the initial step in the methionine salvage pathway; affects polyamine biosynthesis through regulation of ornithine decarboxylase (Spe1p) activity; regulates ADH2 gene expression" Verified chr12:177607-178620 177607-178620 98.8% 291.54 180.71 193.69 177.72 78.88 57.91 236.13 185.71 68.39 0.87 0.75 0.28 -1.44 -1.22 Covered/w/another[3784]
YLR018C POM34 Integral membrane protein of the nuclear pore; has an important role in maintaining the architecture of the pore complex Verified chr12:178706-179605 178706-179605 98.9% 220.12 194.29 203.28 172.95 195.41 131.40 207.21 188.11 163.41 0.76 0.76 0.68 -0.20 -0.33 Covered/w/another[3784]
YLR019W PSR2 "Functionally redundant Psr1p homolog, a plasma membrane phosphatase involved in the general stress response; required with Psr1p and Whi2p for full activation of STRE-mediated gene expression, possibly through dephosphorylation of Msn2p" Verified chr12:180287-181480 180287-181480 98.6% 251.45 267.59 269.29 282.88 279.48 250.60 259.52 276.09 265.04 0.96 1.12 1.10 -0.06 0.33 Matched[3785]
YLR020C YEH2 "Steryl ester hydrolase, catalyzes steryl ester hydrolysis at the plasma membrane; involved in sterol metabolism" Verified chr12:181788-183404 181788-183404 99.2% 192.71 200.20 140.33 135.34 91.06 63.61 196.46 137.83 77.33 0.73 0.56 0.32 -0.83 -0.54 Matched[3786]
YLR021W IRC25 Chaperone component involved in 20S proteasome assembly; forms a heterodimer with Poc4p; IRC25 is a non-essential gene; null mutant displays increased levels of spontaneous Rad52 foci Verified chr12:183622-184161 183622-184161 98.5% 146.61 129.69 148.48 95.86 135.33 75.18 138.15 122.17 105.25 0.51 0.50 0.44 -0.22 -0.11 Matched[3787]
YLR022C SDO1 Essential protein involved in 60S ribosome maturation; ortholog of the human protein (SBDS) responsible for autosomal recessive Shwachman-Bodian-Diamond Syndrome; highly conserved across archae and eukaryotes Verified chr12:184173-184925 184173-184925 99.5% 233.68 197.63 214.99 133.53 161.58 109.50 215.66 174.26 135.54 0.80 0.71 0.56 -0.36 -0.40 Matched[3787]
YLR023C IZH3 "Membrane protein involved in zinc metabolism, member of the four-protein IZH family, expression induced by zinc deficiency; deletion reduces sensitivity to elevated zinc and shortens lag phase, overexpression reduces Zap1p activity" Verified chr12:185497-187128 185497-187128 99.0% 201.86 237.15 205.57 182.66 123.84 102.17 219.50 194.12 113.00 0.81 0.79 0.47 -0.78 -0.27 Matched[3789]
YLR024C UBR2 Cytoplasmic ubiquitin-protein ligase (E3) Verified chr12:187664-193282 187664-193282 99.2% 40.54 39.10 32.11 29.60 52.38 56.14 39.82 30.85 54.26 0.15 0.13 0.22 0.81 0.40 Matched[3790]
YLR025W SNF7 One of four subunits of the endosomal sorting complex required for transport III (ESCRT-III); involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway; recruited from the cytoplasm to endosomal membranes Verified chr12:194453-195175 194453-195175 98.0% 465.66 506.59 434.62 450.14 883.35 733.77 486.12 442.38 808.56 1.79 1.80 3.35 0.87 0.85 Matched[3791]
YLR026C SED5 "cis-Golgi t-SNARE syntaxin required for vesicular transport between the ER and the Golgi complex, binds at least 9 SNARE proteins" Verified chr12:195451-196473 195451-196473 99.1% 178.49 180.46 210.04 203.14 171.58 131.15 179.47 206.59 151.37 0.66 0.84 0.63 -0.45 -0.15 Matched[3792]
YLR027C AAT2 "Cytosolic aspartate aminotransferase, involved in nitrogen metabolism; localizes to peroxisomes in oleate-grown cells" Verified chr12:196830-198086 196830-198086 98.6% 1137.02 1463.84 1103.12 1098.28 806.16 747.25 1300.43 1100.70 776.71 4.80 4.47 3.22 -0.50 -0.14 Matched[3793]
YLR028C ADE16 "Enzyme of 'de novo' purine biosynthesis containing both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities, isozyme of Ade17p; ade16 ade17 mutants require adenine and histidine" Verified chr12:199541-201316 199541-201316 99.0% 637.21 710.60 689.55 673.05 1509.39 1380.81 673.90 681.30 1445.10 2.49 2.77 5.99 1.08 1.47 Matched[3795]
YLR029C RPL15A "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl15Bp and has similarity to rat L15 ribosomal protein; binds to 5.8 S rRNA" Verified chr12:201977-202591 201977-202591 60.9% 15161.13 12102.75 12844.66 9404.65 4243.30 2679.42 13631.93 11124.65 3461.36 50.32 45.16 14.34 -1.68 -2.79 Matched[3796]
YLR030W Putative protein of unknown function Uncharacterized chr12:203291-204082 203291-204082 98.5% 51.29 87.19 44.88 25.65 47.44 38.47 69.24 35.26 42.96 0.26 0.14 0.18 0.28 2.30 Matched[3797]
YLR031W Putative protein of unknown function Uncharacterized chr12:204226-204786 204226-204786 98.9% 46.87 48.67 36.05 27.04 91.94 34.25 47.77 31.55 63.10 0.18 0.13 0.26 1.00 2.33 Covered/w/another[3797]
YLR032W RAD5 "Single-stranded DNA-dependent ATPase, involved in postreplication repair; contains RING finger domain" Verified chr12:204992-208501 204992-208501 98.7% 62.08 56.01 53.70 45.62 36.38 39.27 59.05 49.66 37.82 0.22 0.20 0.16 -0.39 -0.02 Matched[3798]
YLR033W RSC58 "Component of the RSC chromatin remodeling complex; RSC functions in transcriptional regulation and elongation, chromosome stability, and establishing sister chromatid cohesion; involved in telomere maintenance58KDa subunit" Verified chr12:208762-210270 208762-210270 98.7% 218.19 190.67 196.04 177.91 153.74 130.92 204.43 186.98 142.33 0.75 0.76 0.59 -0.39 -0.14 Matched[3799]
YLR034C SMF3 Putative divalent metal ion transporter involved in iron homeostasis; transcriptionally regulated by metal ions; member of the Nramp family of metal transport proteins Verified chr12:210513-211934 210513-211934 98.9% 347.82 275.27 317.23 236.14 384.80 297.31 311.54 276.69 341.06 1.15 1.12 1.41 0.30 0.77 Frag>80[3800]
YLR035C MLH2 Protein involved in the mismatch repair of certain frameshift intermediates and involved in meiotic recombination; forms a complex with Mlh1p Verified chr12:212370-214457 212370-214457 99.1% 59.90 64.25 41.54 42.99 73.43 60.87 62.07 42.27 67.15 0.23 0.17 0.28 0.67 0.96 Matched[3801]
YLR036C Putative protein of unknown function predicted to have transmembrane domains; interacts with HSP90 by yeast two-hybrid analysis; YLR036C is not an essential protein Uncharacterized chr12:221522-222133 221522-222133 99.3% 144.76 129.95 133.24 121.73 185.88 113.50 137.35 127.48 149.69 0.51 0.52 0.62 0.23 -0.25 Matched[3803]
YLR037C DAN2 "Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth" Verified chr12:222686-223060 222686-223060 49.2% 48.74 70.40 21.66 27.08 70.40 37.91 59.57 24.37 54.15 0.22 0.10 0.22 1.15 1.03 Frag<80[3804]
YLR038C COX12 "Subunit VIb of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; required for assembly of cytochrome c oxidase but not required for activity after assembly; phosphorylated" Verified chr12:224922-225173 224922-225173 99.2% 692.23 636.21 736.25 744.25 1340.45 880.29 664.22 740.25 1110.37 2.45 3.00 4.60 0.58 0.31 Matched[3806]
YLR039C RIC1 Protein involved in retrograde transport to the cis-Golgi network; forms heterodimer with Rgp1p that acts as a GTP exchange factor for Ypt6p; involved in transcription of rRNA and ribosomal protein genes Verified chr12:225427-228597 225427-228597 99.3% 96.25 79.09 83.22 76.87 71.15 67.02 87.67 80.05 69.09 0.32 0.32 0.29 -0.21 0.35 Matched[3807]
YLR041W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YLR040C" Dubious chr12:229378-229698 229378-229698 98.6% 78.96 53.69 82.12 56.85 50.53 37.90 66.32 69.48 44.22 0.24 0.28 0.18 -0.65 -0.21 Covered/w/another[3808]
YLR040C Putative protein of unknown function; localizes to the cell wall; predicted to be a GPI-attached protein; upregulated by Mcm1p-Alpha1p transcription factor; partially overlaps the dubious ORF YLR041W; YLR040C is not essential Uncharacterized chr12:228909-229583 228909-229583 98.3% 98.00 48.24 82.92 76.89 75.38 69.35 73.12 79.90 72.37 0.27 0.32 0.30 -0.14 -0.07 Covered/w/another[3808]
YLR042C Protein of unknown function; localizes to the cytoplasm; YLL042C is not an essential gene Uncharacterized chr12:229967-230452 229967-230452 98.4% 144.21 106.59 173.47 131.67 54.34 35.53 125.40 152.57 44.94 0.46 0.62 0.19 -1.76 -2.27 Covered/w/another[3808]
YLR043C TRX1 "Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance" Verified chr12:231703-232014 231703-232014 98.7% 3191.13 3519.00 3093.74 3152.17 3077.51 2162.05 3355.07 3122.95 2619.78 12.39 12.68 10.85 -0.25 -0.60 Matched[3809]
YLR044C PDC1 "Major of three pyruvate decarboxylase isozymes, key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde; subject to glucose-, ethanol-, and autoregulation; involved in amino acid catabolism" Verified chr12:232391-234082 232391-234082 83.9% 22876.87 13959.49 20799.01 17382.42 12519.29 9649.46 18418.18 19090.72 11084.38 67.99 77.49 45.93 -0.78 -1.92 Matched[3810]
YLR045C STU2 Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p Verified chr12:235038-237704 235038-237704 99.2% 170.40 156.05 153.78 143.95 127.33 124.31 163.22 148.87 125.82 0.60 0.60 0.52 -0.24 0.11 Covered/w/another[3811]
YLR046C "Putative membrane protein, transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance" Uncharacterized chr12:238002-238814 238002-238814 99.0% 114.31 157.80 131.70 93.19 130.46 108.10 136.05 112.45 119.28 0.50 0.46 0.49 0.09 0.49 Covered/w/another[3811]
YLR047C FRE8 "Protein with sequence similarity to iron/copper reductases, involved in iron homeostasis; deletion mutant has iron deficiency/accumulation growth defects; expression increased in the absence of copper-responsive transcription factor Mac1p" Verified chr12:239348-241408 239348-241408 98.9% 51.50 72.60 51.50 38.26 37.77 77.01 62.05 44.88 57.39 0.23 0.18 0.24 0.35 1.15 Covered/w/another[3811]
YLR048W RPS0B "Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Ap; required for maturation of 18S rRNA along with Rps0Ap; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal" Verified chr12:242233-243350 242233-242322,242682-243350 81.2% 6303.33 5025.14 5442.01 4436.33 676.40 434.71 5664.23 4939.17 555.56 20.91 20.05 2.30 -3.15 -1.81 Matched[3812]
YLR049C Putative protein of unknown function Uncharacterized chr12:243887-245173 243887-245173 99.2% 176.31 172.39 184.93 122.24 246.83 141.05 174.35 153.58 193.94 0.64 0.62 0.80 0.34 0.27 Covered/w/another[3813]
YLR050C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YLR050C is not an essential gene Uncharacterized chr12:245588-246073 245588-246073 98.8% 256.16 306.14 249.91 216.59 264.49 172.86 281.15 233.25 218.67 1.04 0.95 0.91 -0.09 0.03 Covered/w/another[3813]
YLR051C FCF2 Essential nucleolar protein involved in the early steps of 35S rRNA processing; interacts with Faf1p; member of a transcriptionally co-regulated set of genes called the RRB regulon Verified chr12:246325-246978 246325-246978 99.5% 308.76 227.34 178.19 182.80 64.52 30.72 268.05 180.49 47.62 0.99 0.73 0.20 -1.92 -2.49 Covered/w/another[3813]
YLR052W IES3 Subunit of the INO80 chromatin remodeling complex Verified chr12:247202-247954 247202-247954 98.8% 209.68 176.08 154.57 155.91 122.31 104.84 192.88 155.24 113.58 0.71 0.63 0.47 -0.45 -0.08 Matched[3814]
YLR053C Putative protein of unknown function Uncharacterized chr12:248101-248427 248101-248427 99.4% 46.15 46.15 30.77 24.62 70.77 67.69 46.15 27.69 69.23 0.17 0.11 0.29 1.32 1.77 Matched[3815]
YLR054C OSW2 Protein of unknown function proposed to be involved in the assembly of the spore wall Uncharacterized chr12:248718-250979 248718-250861,250949-250979 99.2% 3.24 5.56 5.56 3.24 16.68 12.05 4.40 4.40 14.36 0.02 0.02 0.06 1.71 1.40 Frag<80[3815]
YLR055C SPT8 "Subunit of the SAGA transcriptional regulatory complex but not present in SAGA-like complex SLIK/SALSA, required for SAGA-mediated inhibition at some promoters" Verified chr12:251273-253081 251273-253081 98.4% 105.62 113.48 121.35 88.20 92.13 94.94 109.55 104.77 93.54 0.40 0.43 0.39 -0.16 0.21 Matched[3816]
YLR056W ERG3 "C-5 sterol desaturase, catalyzes the introduction of a C-5(6) double bond into episterol, a precursor in ergosterol biosynthesis; mutants are viable, but cannot grow on non-fermentable carbon sources" Verified chr12:253862-254959 253862-254959 98.9% 1157.19 2273.88 994.25 832.22 186.88 88.38 1715.54 913.23 137.63 6.33 3.71 0.57 -2.73 -2.52 Matched[3817]
YLR057W Putative protein of unknown function; YLR050C is not an essential gene Uncharacterized chr12:255307-257856 255307-257856 98.8% 90.08 90.08 69.05 55.16 34.92 33.33 90.08 62.10 34.13 0.33 0.25 0.14 -0.86 -0.63 Matched[3818]
YLR058C SHM2 "Cytosolic serine hydroxymethyltransferase, involved in one-carbon metabolism" Verified chr12:257993-259402 257993-259402 98.7% 5143.68 3410.91 5624.48 3814.10 884.71 462.84 4277.30 4719.29 673.77 15.79 19.16 2.79 -2.81 -3.02 Covered/w/another[3819]
YLR059C REX2 "RNA exonuclease, required for U4 snRNA maturation; functions redundantly with Rnh70p in 5.8S rRNA maturation, and with Rnh70p and Rex3p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases" Verified chr12:259739-260548 259739-260548 98.6% 470.91 454.63 398.27 390.75 298.07 286.80 462.77 394.51 292.44 1.71 1.60 1.21 -0.43 -0.12 Covered/w/another[3819]
YLR060W FRS1 "Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs2p to generate active enzyme; sequence is evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase (Msf1p), but substrate binding is similar" Verified chr12:260980-262767 260980-262767 98.9% 1056.83 840.15 1003.65 881.45 363.78 452.04 948.49 942.55 407.91 3.50 3.83 1.69 -1.21 -0.32 Matched[3820]
YLR061W RPL22A "Protein component of the large (60S) ribosomal subunit, has similarity to Rpl22Bp and to rat L22 ribosomal protein" Verified chr12:263195-263949 263195-263206,263596-263949 98.7% 9354.24 7931.73 8128.23 6691.88 1848.71 1544.28 8642.99 7410.06 1696.49 31.91 30.08 7.03 -2.13 -3.01 Matched[3821]
YLR062C BUD28 "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene RPL22A; diploid mutant displays a weak budding pattern phenotype in a systematic assay" Dubious chr12:263578-263955 263578-263955 98.7% 9262.12 7862.35 7985.70 6593.97 1823.46 1515.08 8562.23 7289.83 1669.27 31.61 29.59 6.92 -2.13 -0.88 Matched[3821]
YLR063W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLR063W is not an essential gene Uncharacterized chr12:264158-265255 264158-265255 98.9% 65.40 73.69 38.69 38.69 11.97 26.71 69.55 38.69 19.34 0.26 0.16 0.08 -1.00 -1.71 Matched[3822]
YLR064W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YLR064W is not an essential gene Uncharacterized chr12:265457-266278 265457-266278 99.3% 307.65 333.38 246.36 268.42 872.68 669.22 320.51 257.39 770.95 1.18 1.04 3.19 1.58 0.95 Matched[3823]
YLR065C Putative protein of unknown function; YLR065C is not an essential gene Uncharacterized chr12:266374-266919 266374-266919 99.2% 660.82 623.90 537.15 544.53 278.73 153.21 642.36 540.84 215.97 2.37 2.20 0.89 -1.32 -1.04 Matched[3824]
YLR066W SPC3 "Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway; homologous to mammalian SPC22/23" Verified chr12:267170-267724 267170-267724 98.9% 513.62 566.44 473.55 477.20 435.30 293.24 540.03 475.37 364.27 1.99 1.93 1.51 -0.38 -0.41 Matched[3825]
YLR067C PET309 "Specific translational activator for the COX1 mRNA, also influences stability of intron-containing COX1 primary transcripts; located in the mitochondrial inner membrane" Verified chr12:267814-270711 267814-270711 99.3% 54.54 55.23 49.67 44.81 40.99 31.61 54.88 47.24 36.30 0.20 0.19 0.15 -0.38 -0.40 Matched[3826]
YLR068W FYV7 "Protein of unknown function, required for survival upon exposure to K1 killer toxin; involved in processing the 35S rRNA primary transcript to generate the 20S and 27SA2 pre-rRNA transcripts" Verified chr12:271009-271464 271009-271464 97.8% 177.20 197.38 143.55 116.64 20.19 6.73 187.29 130.09 13.46 0.69 0.53 0.06 -3.27 -1.95 Covered/w/another[3827]
YLR069C MEF1 Mitochondrial elongation factor involved in translational elongation Verified chr12:271631-273916 271631-273916 99.1% 223.82 241.04 265.32 269.74 256.93 211.46 232.43 267.53 234.20 0.86 1.09 0.97 -0.19 0.20 Covered/w/another[3827]
YLR070C XYL2 "Xylitol dehydrogenase, converts xylitol to D-xylulose in the endogenous xylose utilization pathway" Verified chr12:274142-275212 274142-275212 99.0% 21.70 24.53 30.19 33.03 157.58 98.13 23.12 31.61 127.86 0.09 0.13 0.53 2.02 2.48 Covered/w/another[3827]
YLR071C RGR1 "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for glucose repression, HO repression, RME1 repression and sporulation" Verified chr12:275379-278627 275379-278627 99.2% 107.30 111.64 95.51 92.10 55.20 74.12 109.47 93.81 64.66 0.40 0.38 0.27 -0.54 -0.12 Covered/w/another[3827]
YLR072W Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; YLR072W is not an esssential gene Uncharacterized chr12:278863-280944 278863-280944 98.6% 103.81 117.94 114.04 89.19 122.81 104.29 110.87 101.61 113.55 0.41 0.41 0.47 0.16 0.21 Matched[3828]
YLR073C Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to endosomes; YLR073C is not an esssential gene Uncharacterized chr12:281020-281622 281020-281622 98.7% 144.47 120.95 100.79 62.15 18.48 21.84 132.71 81.47 20.16 0.49 0.33 0.08 -2.01 -0.95 Matched[3829]
YLR074C BUD20 Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern Verified chr12:281957-282457 281957-282457 99.1% 443.25 274.01 308.26 193.42 102.75 68.50 358.63 250.84 85.63 1.32 1.02 0.35 -1.55 -1.10 Matched[3830]
YLR075W RPL10 "Protein component of the large (60S) ribosomal subunit, responsible for joining the 40S and 60S subunits; regulates translation initiation; has similarity to rat L10 ribosomal protein and to members of the QM gene family" Verified chr12:282928-283593 282928-283593 98.5% 19100.95 15299.05 16784.76 13801.14 5833.14 4315.43 17200.00 15292.95 5074.29 63.49 62.08 21.02 -1.59 -1.91 Matched[3832]
YLR076C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the essential gene RPL10 which encodes the ribosomal protein L10" Dubious chr12:283186-283608 283186-283608 98.4% 21012.62 16705.79 18352.09 14905.67 6513.12 4539.96 18859.20 16628.88 5526.54 69.62 67.50 22.90 -1.59 -0.82 Matched[3832]
YLR077W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr12:283873-285624 283873-285624 98.6% 117.55 140.14 124.50 114.66 132.61 82.81 128.85 119.58 107.71 0.48 0.49 0.45 -0.15 0.06 Matched[3833]
YLR078C BOS1 "v-SNARE (vesicle specific SNAP receptor), localized to the endoplasmic reticulum membrane and necessary for vesicular transport from the ER to the Golgi" Verified chr12:285737-286560 285737-286468,286558-286560 99.2% 233.20 259.26 289.44 204.39 389.57 190.67 246.23 246.91 290.12 0.91 1.00 1.20 0.23 -0.04 Matched[3834]
YLR079W SIC1 "Inhibitor of Cdc28-Clb kinase complexes that controls G1/S phase transition, preventing premature S phase and ensuring genomic integrity; phosphorylation targets Sic1p for SCF(CDC4)-dependent turnover; functional homolog of mammalian Kip1" Verified chr12:286821-287675 286821-287675 98.3% 304.52 354.48 324.74 279.54 609.04 431.80 329.50 302.14 520.42 1.22 1.23 2.16 0.78 0.98 Matched[3835]
YLR080W EMP46 "Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport" Verified chr12:287917-289251 287917-289251 98.4% 59.38 72.32 70.80 69.27 275.57 137.79 65.85 70.04 206.68 0.24 0.28 0.86 1.56 1.33 Frag>80[3836,3837]
YLR081W GAL2 "Galactose permease, required for utilization of galactose; also able to transport glucose" Verified chr12:290213-291937 290213-291937 96.7% 19.79 16.19 16.19 23.99 14.39 19.19 17.99 20.09 16.79 0.07 0.08 0.07 -0.26 0.45 Frag<80[3838]
YLR082C SRL2 Protein of unknown function; overexpression suppresses the lethality caused by a rad53 null mutation Verified chr12:292395-293573 292395-293573 99.3% 92.22 111.00 81.12 98.20 121.25 80.26 101.61 89.66 100.76 0.38 0.36 0.42 0.17 0.33 Matched[3839]
YLR083C EMP70 "Protein whose 24kDa cleavage product is found in endosome-enriched membrane fractions, predicted to be a transmembrane protein" Verified chr12:294092-296095 294092-296095 98.9% 463.87 361.91 386.64 374.53 66.12 49.97 412.89 380.58 58.05 1.52 1.54 0.24 -2.71 -1.89 Frag>80[3840,3841]
YLR084C RAX2 N-glycosylated protein involved in the maintenance of bud site selection during bipolar budding; localization requires Rax1p Verified chr12:296590-300252 296590-300252 99.0% 104.80 76.67 81.91 60.68 49.64 46.89 90.74 71.29 48.26 0.33 0.29 0.20 -0.56 -0.18 Matched[3842]
YLR085C ARP6 "Actin-related protein that binds nucleosomes; a component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A" Verified chr12:300674-301990 300674-301990 99.0% 87.42 98.92 70.55 89.72 109.66 70.55 93.17 80.13 90.10 0.34 0.33 0.37 0.17 0.11 Matched[3843]
YLR086W SMC4 "Subunit of the condensin complex, which reorganizes chromosomes during cell division, forms a stable complex with Smc2p that has ATP-hydrolyzing and DNA-binding activity and promotes knotting of circular DNA; potential Cdc28p substrate" Verified chr12:302244-306500 302244-306500 98.5% 132.86 131.19 92.07 90.88 72.27 77.76 132.03 91.48 75.02 0.49 0.37 0.31 -0.29 0.19 Matched[3844]
YLR087C CSF1 "Protein required for fermentation at low temperature; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr12:306856-315732 306856-315732 99.1% 33.29 33.74 26.47 24.66 12.95 26.81 33.52 25.56 19.88 0.12 0.10 0.08 -0.36 -0.07 Frag<80[3845]
YLR088W GAA1 "Subunit of the GPI (glycosylphosphatidylinositol):protein transamidase complex, removes the GPI-anchoring signal and attaches GPI to proteins in the ER" Verified chr12:316108-317952 316108-317952 99.0% 224.00 233.31 198.26 185.66 169.23 119.94 228.65 191.96 144.58 0.84 0.78 0.60 -0.41 -0.16 Matched[3846]
YLR089C ALT1 "Putative alanine transaminase (glutamic pyruvic transaminase); the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr12:318238-320016 318238-320016 98.8% 480.52 781.35 602.22 650.55 430.48 349.73 630.94 626.39 390.11 2.33 2.54 1.62 -0.68 -0.41 Matched[3847]
YLR090W XDJ1 "Putative chaperone, homolog of E. coli DnaJ, closely related to Ydj1p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr12:320702-322081 320702-322081 98.4% 135.48 159.77 161.98 138.42 189.96 156.09 147.63 150.20 173.03 0.54 0.61 0.72 0.20 0.40 Matched[3848]
YLR091W "Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YLR091W is not an esssential gene" Uncharacterized chr12:322298-323179 322298-323179 98.8% 98.71 88.38 91.83 76.90 73.46 51.65 93.55 84.37 62.56 0.35 0.34 0.26 -0.43 0.10 Covered/w/another[3849]
YLR092W SUL2 "High affinity sulfate permease; sulfate uptake is mediated by specific sulfate transporters Sul1p and Sul2p, which control the concentration of endogenous activated sulfate intermediates" Verified chr12:323545-326226 323545-326226 98.9% 38.83 51.65 24.51 28.28 54.67 44.11 45.24 26.39 49.39 0.17 0.11 0.20 0.90 0.26 Covered/w/another[3849]
YLR093C NYV1 v-SNARE component of the vacuolar SNARE complex involved in vesicle fusion; inhibits ATP-dependent Ca(2+) transport activity of Pmc1p in the vacuolar membrane Verified chr12:326514-327416 326514-327259,327401-327416 99.2% 476.16 506.59 539.65 544.94 834.61 522.46 491.38 542.30 678.53 1.81 2.20 2.81 0.32 0.11 Frag>80[3850,3851]
YLR094C GIS3 Protein of unknown function Verified chr12:327731-329239 327731-329239 98.7% 97.34 130.23 98.68 74.52 82.57 76.53 113.79 86.60 79.55 0.42 0.35 0.33 -0.12 0.35 Matched[3852]
YLR095C IOC2 "Member of a complex (Isw1b) with Isw1p and Ioc4p that exhibits nucleosome-stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing, contains a PHD finger motif" Verified chr12:329678-332116 329678-332116 98.5% 186.57 181.57 170.33 142.01 137.01 145.34 184.07 156.17 141.18 0.68 0.63 0.58 -0.15 0.34 Matched[3853]
YLR096W KIN2 Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; closely related to Kin1p Verified chr12:332591-336034 332591-336034 98.8% 156.35 156.64 132.54 135.48 76.12 95.51 156.49 134.01 85.82 0.58 0.54 0.36 -0.64 -0.13 Covered/w/another[3854]
YLR097C HRT3 "Putative SCF-ubiquitin ligase F-box protein, based on both genetic and physical interactions and sequence similarity; identified in association with Cdc53p, Skp1p and Ubi4 in large and small-scale studies" Verified chr12:336232-337266 336232-337266 99.3% 163.41 172.17 161.47 108.94 285.97 161.47 167.79 135.20 223.72 0.62 0.55 0.93 0.73 0.48 Covered/w/another[3854]
YLR098C CHA4 "DNA binding transcriptional activator, mediates serine/threonine activation of the catabolic L-serine (L-threonine) deaminase (CHA1); Zinc-finger protein with Zn[2]-Cys[6] fungal-type binuclear cluster domain" Verified chr12:337528-339474 337528-339474 99.0% 61.19 71.04 50.82 49.26 74.67 49.26 66.11 50.04 61.97 0.24 0.20 0.26 0.31 0.92 Matched[3855]
YLR099C ICT1 "Protein of unknown function, null mutation leads to an increase in sensitivity to Calcofluor white; expression of the gene is induced in the presence of isooctane" Verified chr12:339745-340929 339745-340929 98.7% 119.71 224.02 131.68 82.94 105.17 66.69 171.86 107.31 85.93 0.63 0.44 0.36 -0.32 0.18 Matched[3856]
YLR099W-A Putative protein of unknown function Uncharacterized chr12:341326-341589 341326-341589 98.2% 270.10 177.49 169.77 192.93 316.40 208.36 223.79 181.35 262.38 0.83 0.74 1.09 0.53 0.36 Covered/w/another[3857]
YLR100W ERG27 "3-keto sterol reductase, catalyzes the last of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants are sterol auxotrophs" Verified chr12:341811-342854 341811-342854 98.8% 412.81 408.93 383.74 338.19 320.75 183.15 410.87 360.96 251.95 1.52 1.47 1.04 -0.52 -0.05 Covered/w/another[3857]
YLR101C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified, essential ORF ERG27/YLR100W" Dubious chr12:342567-342962 342567-342962 98.8% 439.57 442.13 426.79 337.34 416.57 242.79 440.85 382.07 329.68 1.63 1.55 1.37 -0.21 -0.30 Covered/w/another[3857]
YLR102C APC9 "Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" Verified chr12:342971-343768 342971-343768 99.3% 83.28 108.51 80.75 82.01 243.52 165.29 95.89 81.38 204.41 0.35 0.33 0.85 1.33 0.78 Covered/w/another[3857]
YLR103C CDC45 "DNA replication initiation factor; recruited to MCM pre-RC complexes at replication origins; promotes release of MCM from Mcm10p, recruits elongation machinery; mutants in human homolog may cause velocardiofacial and DiGeorge syndromes" Verified chr12:343990-345942 343990-345942 99.3% 71.16 66.52 63.94 47.44 22.17 15.47 68.84 55.69 18.82 0.25 0.23 0.08 -1.57 -1.11 Matched[3858]
YLR104W Putative protein of unknown function; mutant is deficient in amounts of cell wall mannosylphosphate Uncharacterized chr12:346586-346981 346586-346981 98.6% 281.75 204.91 253.58 215.15 373.96 230.52 243.33 234.36 302.24 0.90 0.95 1.25 0.37 0.04 Matched[3860]
YLR105C SEN2 "Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen2p contains the active site for tRNA 5' splice site cleavage and has similarity to Sen34p and to Archaeal tRNA splicing endonuclease" Verified chr12:347048-348181 347048-348181 99.2% 135.16 110.26 118.26 87.14 80.03 52.46 122.71 102.70 66.24 0.45 0.42 0.27 -0.63 -0.97 Matched[3861]
YLR106C MDN1 "Huge dynein-related AAA-type ATPase (midasin), forms extended pre-60S particle with the Rix1 complex (Rix1p-Ipi1p-Ipi3p), may mediate ATP-dependent remodeling of 60S subunits and subsequent export from nucleoplasm to cytoplasm" Verified chr12:349007-363739 349007-363739 99.2% 147.30 81.39 108.49 104.52 37.03 48.12 114.35 106.51 42.58 0.42 0.43 0.18 -1.32 -0.82 Frag<80[3862,3863,3864,3865,3866]
YLR107W REX3 RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly with Rnh70p and Rex2p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases Verified chr12:364117-365331 364117-365331 98.9% 123.94 127.27 105.64 103.15 139.75 94.00 125.61 104.39 116.87 0.46 0.42 0.48 0.16 0.09 Matched[3867]
YLR108C Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YLR108C is not an esssential gene Uncharacterized chr12:366668-368125 366668-368125 99.0% 31.17 13.85 122.61 54.72 95.60 59.57 22.51 88.67 77.58 0.08 0.36 0.32 -0.19 0.41 Matched[3869]
YLR109W AHP1 "Thiol-specific peroxiredoxin, reduces hydroperoxides to protect against oxidative damage; function in vivo requires covalent conjugation to Urm1p" Verified chr12:368782-369312 368782-369312 98.8% 8536.98 3675.59 8931.61 4834.70 29048.22 18534.28 6106.28 6883.15 23791.25 22.54 27.94 98.58 1.79 0.94 Matched[3870]
YLR110C CCW12 "Cell wall mannoprotein, mutants are defective in mating and agglutination, expression is downregulated by alpha-factor" Verified chr12:369698-370099 369698-370099 93.8% 45819.39 49750.86 45864.48 40434.18 31130.76 20479.72 47785.12 43149.33 25805.24 176.40 175.15 106.92 -0.74 -2.31 Matched[3871]
YLR111W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr12:370392-370724 370392-370724 98.6% 9.14 24.37 6.09 3.05 15.23 18.28 16.76 4.57 16.76 0.06 0.02 0.07 1.87 0.27 Matched[3872]
YLR112W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr12:370792-371211 370792-371211 98.8% 57.84 67.48 53.02 53.02 147.00 62.66 62.66 53.02 104.83 0.23 0.22 0.43 0.98 0.45 Matched[3872]
YLR113W HOG1 Mitogen-activated protein kinase involved in osmoregulation via three independent osmosensors; mediates the recruitment and activation of RNA Pol II at Hot1p-dependent promoters; localization regulated by Ptp2p and Ptp3p Verified chr12:371621-372928 371621-372928 98.8% 690.98 652.29 616.69 534.67 660.80 487.47 671.63 575.68 574.14 2.48 2.34 2.38 -0.00 0.61 Matched[3873]
YLR114C AVL9 Conserved protein involved in exocytic transport from the Golgi; mutation is synthetically lethal with apl2 vps1 double mutation; member of a protein superfamily with orthologs in diverse organisms Verified chr12:374945-377239 374945-377239 96.6% 229.98 226.82 212.84 208.33 119.95 114.09 228.40 210.59 117.02 0.84 0.85 0.48 -0.85 -0.16 Matched[3875]
YLR115W CFT2 "Subunit of the mRNA cleavage and polyadenlylation factor (CPF); required for pre-mRNA cleavage, polyadenylation and poly(A) site recognition, 43% similarity with the mammalian CPSF-100 protein." Verified chr12:377986-380565 377986-380565 98.8% 99.62 108.64 87.07 77.26 71.77 71.38 104.13 82.17 71.58 0.38 0.33 0.30 -0.20 0.26 Covered/w/another[3876]
YLR116W MSL5 "Component of the commitment complex, which defines the first step in the splicing pathway; essential protein that interacts with Mud2p and Prp40p, forming a bridge between the intron ends; also involved in nuclear retention of pre-mRNA" Verified chr12:380823-382253 380823-382253 98.6% 152.31 126.80 135.31 114.05 120.43 119.01 139.56 124.68 119.72 0.52 0.51 0.50 -0.06 0.58 Covered/w/another[3876]
YLR117C CLF1 "Essential splicesome assembly factor; contains multiple tetratricopeptide repeat (TPR) protein-binding motifs and interacts specifically with many spliceosome components, may serve as a scaffold during splicesome assembly" Verified chr12:382472-384535 382472-384535 99.4% 103.83 93.59 82.38 85.30 105.78 89.69 98.71 83.84 97.73 0.36 0.34 0.40 0.22 0.31 Covered/w/another[3876]
YLR118C Acyl-protein thioesterase responsible for depalmitoylation of Gpa1p; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus and is induced in response to the DNA-damaging agent MMS Verified chr12:384726-385409 384726-385409 99.0% 320.33 349.86 296.72 327.72 710.05 519.62 335.10 312.22 614.84 1.24 1.27 2.55 0.98 0.82 Frag>80[3877,3878]
YLR119W SRN2 "Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; suppressor of rna1-1 mutation; may be involved in RNA export from nucleus" Verified chr12:385535-386176 385535-386176 98.8% 138.76 121.42 102.50 111.96 321.68 260.18 130.09 107.23 290.93 0.48 0.44 1.21 1.44 1.08 Matched[3879]
YLR120C YPS1 "Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor" Verified chr12:386512-388221 386512-388221 98.7% 197.86 239.92 222.74 188.38 377.94 327.00 218.89 205.56 352.47 0.81 0.83 1.46 0.78 1.08
YLR120W-A "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the verified ORF YLR121C" Dubious chr12:388673-388774 388673-388774 97.6% 90.41 90.41 40.18 30.14 30.14 10.05 90.41 35.16 20.09 0.33 0.14 0.08 -0.81 NaN Covered/w/another[3880]
YLR121C YPS3 "Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor" Verified chr12:388745-390271 388745-390271 98.3% 103.23 114.55 91.24 86.58 165.16 102.56 108.89 88.91 133.86 0.40 0.36 0.55 0.59 -0.33 Covered/w/another[3880]
YLR122C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR123C" Dubious chr12:390955-391332 390955-391332 98.6% 56.37 56.37 37.58 40.26 24.16 16.11 56.37 38.92 20.13 0.21 0.16 0.08 -0.95 -0.67 Covered/w/another[3880]
YLR123C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR122C; contains characteristic aminoacyl-tRNA motif" Dubious chr12:391079-391408 391079-391408 98.4% 52.37 61.61 36.97 24.64 24.64 12.32 56.99 30.80 18.48 0.21 0.13 0.08 -0.74 -0.58 Covered/w/another[3880]
YLR124W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr12:391601-391945 391601-391945 98.8% 14.67 44.01 20.54 23.47 35.21 14.67 29.34 22.00 24.94 0.11 0.09 0.10 0.18 -0.30 Covered/w/another[3880]
YLR125W Putative protein of unknown function; mutant has decreased Ty3 transposition; YLR125W is not an essential gene Uncharacterized chr12:393485-393895 393485-393895 98.2% 27.26 47.09 52.04 4.96 54.52 49.57 37.17 28.50 52.04 0.14 0.12 0.22 0.87 0.43 Covered[3881]
YLR126C Putative protein of unknown function with similarity to glutamine amidotransferase proteins; has Aft1p-binding motif in the promoter; may be involved in copper and iron homeostasis; YLR126C is not an essential protein Uncharacterized chr12:394766-395521 394766-395521 99.5% 228.75 126.34 164.91 129.00 136.98 62.51 177.55 146.96 99.75 0.66 0.60 0.41 -0.56 -0.50 Covered/w/another[3882]
YLR127C APC2 "Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; similar to cullin Cdc53p" Verified chr12:395759-398320 395759-398320 99.2% 64.93 87.35 52.33 52.33 55.09 50.76 76.14 52.33 52.92 0.28 0.21 0.22 0.02 0.20 Covered/w/another[3882]
YLR128W DCN1 Putative Nedd8 ligase; binds Nedd8; involved in cullin neddylation; not essential; similar to C.elegans DCN-1; contains UBA-like ubiquitin-binding domain and a DUF298 domain Verified chr12:398531-399434 398531-398533,398628-399434 98.8% 80.00 75.00 61.25 80.00 76.25 71.25 77.50 70.62 73.75 0.29 0.29 0.31 0.06 0.80 Covered/w/another[3883]
YLR129W DIP2 "Nucleolar protein, specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex" Verified chr12:399658-402489 399658-402489 98.7% 227.85 143.44 131.99 117.32 17.53 6.44 185.64 124.66 11.98 0.69 0.51 0.05 -3.38 -3.09 Covered/w/another[3883]
YLR130C ZRT2 Low-affinity zinc transporter of the plasma membrane; transcription is induced under low-zinc conditions by the Zap1p transcription factor Verified chr12:402795-404063 402795-404063 98.8% 331.78 317.43 248.04 215.34 130.80 66.99 324.60 231.69 98.90 1.20 0.94 0.41 -1.23 -1.00 Covered/w/another[3883]
YLR131C ACE2 "Transcription factor that activates expression of early G1-specific genes, localizes to daughter cell nuclei after cytokinesis and delays G1 progression in daughters, localization is regulated by phosphorylation; potential Cdc28p substrate" Verified chr12:404511-406823 404511-406823 98.9% 144.66 133.30 139.42 111.45 158.65 152.09 138.98 125.43 155.37 0.51 0.51 0.64 0.31 1.06 Covered/w/another[3884]
YLR132C Protein of unknown function; green fluorescent protein (GFP)-tagged protein localizes to mitochondria and nucleus; YLR132C is an essential gene Uncharacterized chr12:407284-408156 407284-408156 98.9% 48.63 49.79 54.42 56.74 177.17 105.37 49.21 55.58 141.27 0.18 0.23 0.59 1.35 1.31 Covered/w/another[3884]
YLR133W CKI1 "Choline kinase, catalyzes the first step in the CDP-choline pathway phosphatidylcholine synthesis (Kennedy pathway); mRNA expression is regulated by inositol and choline, enzyme activity is stimulated by phosphorylation by protein kinase" Verified chr12:408446-410194 408446-410194 98.7% 115.30 117.04 113.56 121.10 178.46 222.49 116.17 117.33 200.47 0.43 0.48 0.83 0.77 1.04 Matched[3885]
YLR134W PDC5 "Minor isoform of pyruvate decarboxylase, key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde, regulation is glucose- and ethanol-dependent, repressed by thiamine, involved in amino acid catabolism" Verified chr12:410724-412415 410724-412415 81.1% 75.77 70.67 71.40 53.18 53.91 33.51 73.22 62.29 43.71 0.27 0.25 0.18 -0.51 -0.44 Matched[3886]
YLR135W SLX4 "Subunit of a complex, with Slx1p, that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks; function overlaps with that of Sgs1p-Top3p" Verified chr12:413282-415528 413282-415528 98.7% 67.21 62.25 45.56 46.91 54.13 52.78 64.73 46.24 53.45 0.24 0.19 0.22 0.21 0.31 Covered/w/another[3887]
YLR136C TIS11 mRNA-binding protein expressed during iron starvation; binds to a sequence element in the 3'-untranslated regions of specific mRNAs to mediate their degradation; involved in iron homeostasis Verified chr12:415802-416659 415802-416659 98.9% 134.29 70.68 126.04 97.77 120.15 98.95 102.48 111.91 109.55 0.38 0.45 0.45 -0.03 0.65 Covered/w/another[3887]
YLR137W Putative protein of unknown function Uncharacterized chr12:417007-418110 417007-418110 98.4% 62.56 63.48 73.61 48.76 182.17 107.65 63.02 61.18 144.91 0.23 0.25 0.60 1.24 1.54 Matched[3888]
YLR138W NHA1 Na+/H+ antiporter involved in sodium and potassium efflux through the plasma membrane; required for alkali cation tolerance at acidic pH Verified chr12:418438-421395 418438-421395 98.4% 210.26 160.10 202.70 172.46 152.88 161.81 185.18 187.58 157.35 0.68 0.76 0.65 -0.25 0.22 Matched[3889]
YLR139C SLS1 Mitochondrial membrane protein required for assembly of respiratory-chain enzyme complexes III and IV; coordinates expression of mitochondrially-encoded genes; may facilitate delivery of mRNA to membrane-bound translation machinery Verified chr12:421543-423474 421543-423474 98.5% 83.03 98.27 94.06 85.66 47.29 63.06 90.65 89.86 55.18 0.33 0.36 0.23 -0.70 0.07 Covered/w/another[3890]
YLR140W Dubious open reading frame unlikely to encode a functional protein; overlaps essential RRN5 gene which encodes a member of the UAF transcription factor involved in transcription of rDNA by RNA polymerase I Dubious chr12:423475-423801 423475-423801 98.2% 46.70 84.06 77.83 84.06 71.60 59.15 65.38 80.94 65.38 0.24 0.33 0.27 -0.31 0.49 Covered/w/another[3890]
YLR141W RRN5 "Protein involved in transcription of rDNA by RNA polymerase I; transcription factor, member of UAF (upstream activation factor) family along with Rrn9p and Rrn10p" Verified chr12:423684-424775 423684-424775 97.1% 63.16 78.24 73.52 53.73 72.58 40.53 70.70 63.63 56.56 0.26 0.26 0.23 -0.17 0.11 Covered/w/another[3890]
YLR142W PUT1 "Proline oxidase, nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; PUT1 transcription is induced by Put3p in the presence of proline and the absence of a preferred nitrogen source" Verified chr12:425187-426617 425187-426617 98.9% 31.79 20.49 32.49 24.02 273.38 283.27 26.14 28.26 278.32 0.10 0.11 1.15 3.30 3.33 Frag>80[3891,3892]
YLR143W Putative protein of unknown function; green fluorescent protein (GFP)-tagged protein localizes to the cytoplasm; YLR143W is not an essential gene Uncharacterized chr12:427330-429387 427330-429387 98.9% 78.14 68.80 69.78 52.58 46.19 46.19 73.47 61.18 46.19 0.27 0.25 0.19 -0.41 -0.07 Covered/w/another[3893]
YLR144C ACF2 "Intracellular beta-1,3-endoglucanase, expression is induced during sporulation; may have a role in cortical actin cytoskeleton assembly" Verified chr12:429678-432017 429678-432017 98.9% 89.84 77.31 73.43 79.47 117.91 100.64 83.58 76.45 109.28 0.31 0.31 0.45 0.52 0.68 Covered/w/another[3893]
YLR145W RMP1 "Subunit of RNase MRP, which processes pre-rRNA and has a role in cell cycle-regulated degradation of daughter cell-specific mRNAs; unlike most subunits, not shared between RNase MRP and nuclear RNase P" Verified chr12:432169-432774 432169-432774 98.4% 129.19 117.44 127.51 98.99 144.29 82.21 123.31 113.25 113.25 0.46 0.46 0.47 0.00 0.13 Covered/w/another[3893]
YLR146C SPE4 "Spermine synthase, required for the biosynthesis of spermine and also involved in biosynthesis of pantothenic acid" Verified chr12:432824-433726 432824-433726 99.1% 191.15 145.32 158.73 149.79 51.42 20.12 168.23 154.26 35.77 0.62 0.63 0.15 -2.11 -1.55 Covered/w/another[3893]
YLR146W-A Putative protein of unknown function Uncharacterized chr12:433871-434059 433871-434059 98.8% 224.90 176.71 171.35 208.84 240.96 101.74 200.80 190.09 171.35 0.74 0.77 0.71 -0.15 NaN Covered/w/another[3893]
YLR147C SMD3 "Core Sm protein Sm D3; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm D3" Verified chr12:434159-434464 434159-434464 99.2% 171.29 128.47 167.99 177.88 200.93 102.11 149.88 172.93 151.52 0.55 0.70 0.63 -0.19 -0.61 Covered/w/another[3893]
YLR148W PEP3 "Component of CORVET tethering complex; vacuolar peripheral membrane protein that promotes vesicular docking/fusion reactions in conjunction with SNARE proteins, required for vacuolar biogenesis" Verified chr12:434642-437398 434642-437398 99.0% 93.03 90.83 83.14 82.78 120.50 99.62 91.93 82.96 110.06 0.34 0.34 0.46 0.41 0.55 Covered/w/another[3893]
YLR149C Putative protein of unknown function; YLR149C is not an essential gene Uncharacterized chr12:437632-439824 437632-439824 99.1% 38.65 56.13 68.10 99.38 377.29 386.95 47.39 83.74 382.12 0.17 0.34 1.58 2.19 2.12 Matched[3894]
YLR149C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr12:440371-440457 440371-440457 98.9% 3767.44 3255.81 3697.67 3441.86 1430.23 1511.63 3511.63 3569.77 1470.93 12.96 14.49 6.09 -1.28 -0.17 Matched[3895]
YLR150W STM1 Protein that binds G4 quadruplex and purine motif triplex nucleic acid; acts with Cdc13p to maintain telomere structure; interacts with ribosomes and subtelomeric Y' DNA; multicopy suppressor of tom1 and pop2 mutations Verified chr12:440468-441289 440468-441289 98.3% 7486.85 6666.39 7051.25 6548.83 2889.55 2832.63 7076.62 6800.04 2861.09 26.12 27.60 11.85 -1.25 -1.39 Frag>80[3895,3896,3897,3898]
YLR151C PCD1 "Peroxisomal nudix pyrophosphatase with specificity for coenzyme A and CoA derivatives, may function to remove potentially toxic oxidized CoA disulfide from peroxisomes to maintain the capacity for beta-oxidation of fatty acids" Verified chr12:441716-442738 441716-442738 99.5% 95.33 109.09 115.97 134.64 332.17 224.07 102.21 125.30 278.12 0.38 0.51 1.15 1.15 0.96 Frag>80[3897,3898,3899]
YLR152C Putative protein of unknown function; YLR152C is not an essential gene Uncharacterized chr12:442959-444689 442959-444689 98.9% 67.16 153.60 76.51 63.07 269.23 212.00 110.38 69.79 240.61 0.41 0.28 1.00 1.79 1.90 Matched[3900]
YLR153C ACS2 "Acetyl-coA synthetase isoform which, along with Acs1p, is the nuclear source of acetyl-coA for histone acetylation; mutants affect global transcription; required for growth on glucose; expressed under anaerobic conditions" Verified chr12:445525-447576 445525-447576 98.9% 761.54 815.26 734.92 631.41 272.08 223.78 788.40 683.17 247.93 2.91 2.77 1.03 -1.46 -0.83 Matched[3901]
YLR154C RNH203 "Ribonuclease H2 subunit, required for RNase H2 activity" Verified chr12:447983-448315 447983-448315 99.0% 227.53 279.11 209.33 215.40 285.17 206.30 253.32 212.36 245.73 0.94 0.86 1.02 0.21 0.03 Matched[3902]
YLR154W-A Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand Dubious chr12:452439-452624 452439-452624 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YLR154W-B Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand Dubious chr12:454393-454557 454393-454557 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YLR154W-C TAR1 "Mitochondrial protein of unknown function, overexpression suppresses an rpo41 mutation affecting mitochondrial RNA polymerase; encoded within the 25S rRNA gene on the opposite strand" Verified chr12:454697-455071 454697-455071 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YLR154W-E Dubious open reading frame unlikely to encode a protein; encoded within the the 35S rRNA gene on the opposite strand Dubious chr12:455434-455637 455434-455637 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YLR154W-F Dubious open reading frame unlikely to encode a protein; encoded within the the 35S rRNA gene on the opposite strand Dubious chr12:455884-456024 455884-456024 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YLR154C-G Putative protein of unknown function identified by fungal homology comparisons and RT-PCR; this ORF is contained within RDN25-2 and RDN37-2 Uncharacterized chr12:462523-462672 462523-462672 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YLR154C-H Putative protein of unknown function identified by fungal homology comparisons and RT-PCR; this ORF partially overlaps RND5-2 Uncharacterized chr12:468828-468959 468828-468959 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YLR155C ASP3-1 "Cell-wall L-asparaginase II, involved in asparagine catabolism; expression is induced during nitrogen starvation; four copies of ASP3 are present in the genome reference strain S288C" Verified chr12:469318-470406 469318-470406 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.40
YLR156W Putative protein of unknown function; exhibits a two-hybrid interaction with Jsn1p in a large-scale analysis Uncharacterized chr12:472114-472458 472114-472458 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.49
YLR156C-A Putative protein of unknown function identified by fungal homology comparisons and RT-PCR; this ORF partially overlaps RND5-3 Uncharacterized chr12:472480-472611 472480-472611 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YLR157C ASP3-2 "Cell-wall L-asparaginase II, involved in asparagine catabolism; expression is induced during nitrogen starvation; four copies of ASP3 are present in the genome reference strain S288C" Verified chr12:472970-474058 472970-474058 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.41
YLR157W-D "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr12:475765-475977 475765-475977 10.0% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN NaN
YLR157W-E "Putative protein of unknown function identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; partially overlaps a Ty1 element" Uncharacterized chr12:481874-482038 481874-482038 14.0% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN NaN
YLR157C-C Putative protein of unknown function identified by fungal homology comparisons and RT-PCR; this ORF partially overlaps RND5-4 Uncharacterized chr12:482060-482191 482060-482191 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YLR158C ASP3-3 "Cell-wall L-asparaginase II, involved in asparagine catabolism; expression is induced during nitrogen starvation; four copies of ASP3 are present in the genome reference strain S288C" Verified chr12:482550-483638 482550-483638 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.39
YLR159W "Putative protein of unknown function; YLR156W, YLR159W, and YLR161W are three identical open reading frames encoded near the ribosomal DNA region of chromosome 12" Uncharacterized chr12:485346-485690 485346-485690 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.48
YLR159C-A Putative protein of unknown function identified by fungal homology comparisons and RT-PCR; this ORF partially overlaps RND5-5 Uncharacterized chr12:485712-485843 485712-485843 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YLR160C ASP3-4 "Cell-wall L-asparaginase II, involved in asparagine catabolism; expression is induced during nitrogen starvation; four copies of ASP3 are present in the genome reference strain S288C" Verified chr12:486202-487290 486202-487290 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.44
YLR161W "Putative protein of unknown function; YLR156W, YLR159W, and YLR161W are three identical open reading frames encoded near the ribosomal DNA region of chromosome 12" Uncharacterized chr12:488998-489342 488998-489342 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.51
YLR162W Putative protein of unknown function; overexpression confers resistance to the antimicrobial peptide MiAMP1 Uncharacterized chr12:489574-489930 489574-489930 62.6% 8689.04 8568.23 4876.96 6483.22 1082.77 5664.43 8628.64 5680.09 3373.60 31.85 23.06 13.98 -0.75 0.21 Frag<80[3907,3908]
YLR162W-A Putative protein of unknown function identified by fungal homology comparisons and RT-PCR Uncharacterized chr12:490407-490595 490407-490595 46.2% 137.40 34.35 45.80 22.90 34.35 91.60 85.88 34.35 62.98 0.32 0.14 0.26 0.87 NaN Matched[3908]
YLR163W-A "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data" Dubious chr12:492814-492927 492814-492927 99.6% 123.35 114.54 105.73 140.97 176.21 132.16 118.94 123.35 154.19 0.44 0.50 0.64 0.32 NaN Covered/w/another[3910]
YLR163C MAS1 "Smaller subunit of the mitochondrial processing protease (MPP), essential processing enzyme that cleaves the N-terminal targeting sequences from mitochondrially imported proteins" Verified chr12:491868-493256 491868-493256 99.2% 169.84 152.42 166.94 161.86 209.04 154.60 161.13 164.40 181.82 0.59 0.67 0.75 0.15 0.26 Matched[3910]
YLR164W "Mitochondrial inner membrane of unknown function; similar to Tim18p and Sdh4p; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner" Verified chr12:493885-494391 493885-494391 98.8% 57.90 73.87 95.83 65.88 201.65 121.79 65.88 80.86 161.72 0.24 0.33 0.67 1.00 1.34 Covered/w/another[3912]
YLR165C PUS5 "Pseudouridine synthase, catalyzes only the formation of pseudouridine (Psi)-2819 in mitochondrial 21S rRNA; not essential for viability" Verified chr12:494496-495260 494496-495260 99.2% 84.32 98.81 71.14 73.78 140.97 40.84 91.56 72.46 90.90 0.34 0.29 0.38 0.33 0.08 Matched[3912]
YLR166C SEC10 "Essential 100kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis" Verified chr12:495431-498046 495431-498046 99.4% 126.46 123.77 99.94 96.48 134.92 108.78 125.12 98.21 121.85 0.46 0.40 0.50 0.31 0.06 Covered[3913]
YLR167W RPS31 Fusion protein that is cleaved to yield a ribosomal protein of the small (40S) subunit and ubiquitin; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes; interacts genetically with translation factor eIF2B Verified chr12:498949-499407 498949-499407 77.4% 28745.92 24152.10 25318.15 21366.51 8418.73 6300.67 26449.01 23342.33 7359.70 97.64 94.75 30.49 -1.67 -3.59 Covered/w/another[3914]
YLR168C Putative protein of unknown function that may be involved in intramitochondrial sorting; has similarity to Ups1p and to human PRELI; the green fluorescent protein (GFP)-tagged protein localizes to mitochondria Uncharacterized chr12:499580-500272 499580-500272 99.4% 165.50 200.34 184.37 197.44 551.66 344.06 182.92 190.90 447.86 0.68 0.77 1.86 1.23 0.75 Covered/w/another[3914,3915]
YLR169W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr12:500337-500690 500337-500690 99.2% 401.42 384.34 313.17 361.57 663.35 395.73 392.88 337.37 529.54 1.45 1.37 2.19 0.65 -0.07 Covered/w/another[3914,3915]
YLR171W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr12:500735-501124 500735-501124 99.4% 270.76 288.81 268.19 306.87 544.11 327.50 279.79 287.53 435.80 1.03 1.17 1.81 0.60 -0.06 Covered/w/another[3914,3915]
YLR170C APS1 "Small subunit of the clathrin-associated adaptor complex AP-1, which is involved in protein sorting at the trans-Golgi network; homolog of the sigma subunit of the mammalian clathrin AP-1 complex" Verified chr12:500581-501051 500581-501051 99.3% 367.78 365.65 335.71 363.51 669.28 391.30 366.71 349.61 530.29 1.35 1.42 2.20 0.60 -0.15 Covered/w/another[3914,3915]
YLR172C DPH5 "Methyltransferase required for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); not essential for viability; GFP-Dph5p fusion protein localizes to the cytoplasm" Verified chr12:501262-502164 501262-502164 99.0% 461.07 309.99 318.94 315.58 165.63 135.41 385.53 317.26 150.52 1.42 1.29 0.62 -1.08 -0.63 Frag<80[3916]
YLR173W Putative protein of unknown function Uncharacterized chr12:502423-504249 502423-504249 98.8% 70.39 74.83 69.28 59.86 82.03 72.61 72.61 64.57 77.32 0.27 0.26 0.32 0.26 0.84 Matched[3917]
YLR174W IDP2 "Cytosolic NADP-specific isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate; levels are elevated during growth on non-fermentable carbon sources and reduced during growth on glucose" Verified chr12:504593-505831 504593-505831 98.5% 29.49 48.34 25.40 19.66 40.14 21.30 38.92 22.53 30.72 0.14 0.09 0.13 0.45 0.59 Matched[3918]
YLR175W CBF5 "Pseudouridine synthase catalytic subunit of box H/ACA small nucleolar ribonucleoprotein particles (snoRNPs), acts on both large and small rRNAs and on snRNA U2" Verified chr12:506136-507587 506136-507587 96.6% 2268.97 1366.66 1663.39 1499.33 186.17 84.88 1817.81 1581.36 135.52 6.71 6.42 0.56 -3.54 -3.93 Matched[3919]
YLR176C RFX1 Protein involved in DNA damage and replication checkpoint pathway; recruits repressors Tup1p and Cyc8p to promoters of DNA damage-inducible genes; similar to a family of mammalian DNA binding RFX1-4 proteins Verified chr12:507799-510234 507799-510234 98.8% 52.76 57.75 58.16 52.76 138.34 135.43 55.25 55.46 136.89 0.20 0.23 0.57 1.30 1.32 Matched[3920]
YLR177W Putative protein of unknown function; phosphorylated by Dbf2p-Mob1p in vitro; some strains contain microsatellite polymophisms at this locus; YLR177W is not an essential gene Uncharacterized chr12:511056-512942 511056-512942 97.9% 150.98 243.51 252.17 242.97 940.50 675.34 197.24 247.57 807.92 0.73 1.00 3.35 1.71 1.16 Matched[3921]
YLR178C TFS1 "Carboxypeptidase Y inhibitor, function requires acetylation by the NatB N-terminal acetyltransferase; phosphatidylethanolamine-binding protein involved in protein kinase A signaling pathway" Verified chr12:513164-513823 513164-513823 98.6% 187.56 741.02 433.54 384.34 9158.16 6058.80 464.29 408.94 7608.48 1.71 1.66 31.52 4.22 3.26 Frag>80[3922,3923,3924]
YLR179C "Protein of unknown function, transcription is activated by paralogous proteins Yrm1p and Yrr1p along with proteins involved in multidrug resistance; GFP-tagged protein localizes to the cytoplasm and nucleus; YLR179C is not essential" Uncharacterized chr12:514110-514715 514110-514715 98.7% 1307.87 1481.81 1266.06 1030.24 1185.78 1058.68 1394.84 1148.15 1122.23 5.15 4.66 4.65 -0.03 0.04 Frag>80[3923,3924,3925]
YLR180W SAM1 "S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p)" Verified chr12:515264-516412 515264-516412 91.3% 1280.22 707.31 1206.82 828.38 117.25 22.88 993.76 1017.60 70.06 3.67 4.13 0.29 -3.86 -3.08 Matched[3926]
YLR181C VTA1 "Multivesicular body (MVB) protein involved in endosomal protein sorting; regulates Vps4p activity by promoting its oligimeriztion; binds to Vps4p, Vps20p, and Vps60p; may act at a late step in MVB formation" Verified chr12:516680-517672 516680-517672 99.4% 168.18 173.24 158.05 136.77 181.35 152.98 170.71 147.41 167.17 0.63 0.60 0.69 0.18 -0.56 Matched[3927]
YLR182W SWI6 "Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1p to regulate transcription at the G1/S transition; involved in meiotic gene expression; localization regulated by phosphorylation; potential Cdc28p substrate" Verified chr12:517942-520353 517942-520353 98.7% 155.50 132.38 130.28 140.37 139.11 114.73 143.94 135.32 126.92 0.53 0.55 0.53 -0.09 0.19 Matched[3928]
YLR183C TOS4 "Transcription factor that binds to a number of promoter regions, particularly promoters of some genes involved in pheromone response and cell cycle; potential Cdc28p substrate; expression is induced in G1 by bound SBF" Verified chr12:520545-522014 520545-522014 99.0% 226.14 124.41 171.84 151.22 63.92 29.56 175.27 161.53 46.74 0.65 0.66 0.19 -1.79 -1.29 Matched[3929]
YLR184W "Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr12:522108-522455 522108-522455 98.6% 0.00 0.00 0.00 0.00 8.74 0.00 0.00 0.00 4.37 0.00 0.00 0.02 Inf -1.08 Overlap[3929]
YLR185W RPL37A "Protein component of the large (60S) ribosomal subunit, has similarity to Rpl37Bp and to rat L37 ribosomal protein" Verified chr12:522665-523290 522665-522671,523031-523290 77.3% 7535.11 6232.45 6576.27 4707.02 1898.31 924.94 6883.78 5641.65 1411.62 25.41 22.90 5.85 -2.00 -2.92 Matched[3930]
YLR186W EMG1 Protein required for the maturation of the 18S rRNA and for 40S ribosome production; associated with spindle/microtubules; nuclear localization depends on physical interaction with Nop14p; may bind snoRNAs Verified chr12:523634-524392 523634-524392 98.8% 414.55 293.25 303.92 178.62 37.32 10.66 353.90 241.27 23.99 1.31 0.98 0.10 -3.33 -3.11 Frag>80[3931,3932]
YLR187W SKG3 "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; potential Cdc28p substrate; similar to Caf120p and Skg4p" Uncharacterized chr12:524867-527947 524867-527947 98.9% 74.85 59.09 67.63 46.29 36.77 59.75 66.97 56.96 48.26 0.25 0.23 0.20 -0.24 0.66 Matched[3933]
YLR188W MDL1 "Mitochondrial inner membrane half-type ATP-binding cassette (ABC) transporter, mediates export of peptides generated upon proteolysis of mitochondrial proteins, plays a role in the regulation of cellular resistance to oxidative stress" Verified chr12:528302-530389 528302-530389 98.7% 147.08 167.96 142.23 135.43 72.33 72.33 157.52 138.83 72.33 0.58 0.56 0.30 -0.94 -0.55 Frag>80[3934,3935]
YLR189C ATG26 "UDP-glucose:sterol glucosyltransferase, conserved enzyme involved in synthesis of sterol glucoside membrane lipids, involved in autophagy" Verified chr12:530799-534395 530799-534395 99.2% 107.29 140.63 108.41 110.93 166.40 163.32 123.96 109.67 164.86 0.46 0.45 0.68 0.59 0.97 Matched[3936]
YLR190W MMR1 "Phosphorylated protein of the mitochondrial outer membrane, localizes only to mitochondria of the bud; interacts with Myo2p to mediate mitochondrial distribution to buds; mRNA is targeted to the bud via the transport system involving She2p" Verified chr12:535216-536691 535216-536691 98.6% 245.36 279.04 261.86 265.29 309.97 251.55 262.20 263.57 280.76 0.97 1.07 1.16 0.09 0.82 Matched[3937]
YLR191W PEX13 "Integral peroxisomal membrane required for the translocation of peroxisomal matrix proteins, interacts with the PTS1 signal recognition factor Pex5p and the PTS2 signal recognition factor Pex7p, forms a complex with Pex14p and Pex17p" Verified chr12:537274-538434 537274-538434 98.5% 71.68 79.55 75.18 67.31 88.29 53.33 75.62 71.25 70.81 0.28 0.29 0.29 -0.01 0.35 Matched[3938]
YLR192C HCR1 Dual function protein involved in translation initiation as a substoichiometric component of eukaryotic translation initiation factor 3 (eIF3) and required for processing of 20S pre-rRNA; binds to eIF3 subunits Rpg1p and Prt1p and 18S rRNA Verified chr12:538794-539591 538794-539591 99.1% 1125.40 891.46 1131.72 988.83 838.36 737.20 1008.43 1060.27 787.78 3.72 4.30 3.26 -0.43 0.04 Covered/w/another[3939]
YLR193C UPS1 Mitochondrial intermembrane space protein that regulates alternative processing and sorting of Mgm1p and other proteins; required for normal mitochondrial morphology; ortholog of human PRELI Verified chr12:540011-540538 540011-540538 99.0% 160.73 220.04 216.22 187.51 386.51 302.32 190.39 201.87 344.42 0.70 0.82 1.43 0.77 0.82 Covered/w/another[3939]
YLR194C Structural constituent of the cell wall attached to the plasma membrane by a GPI-anchor; expression is upregulated in response to cell wall stress Uncharacterized chr12:540811-541575 540811-541575 98.6% 208.25 205.59 217.53 180.39 427.10 224.16 206.92 198.96 325.63 0.76 0.81 1.35 0.71 1.06 Frag>80[3940,3941]
YLR195C NMT1 "N-myristoyl transferase, catalyzes the cotranslational, covalent attachment of myristic acid to the N-terminal glycine residue of several proteins involved in cellular growth and signal transduction" Verified chr12:541939-543306 541939-543306 99.2% 310.10 265.91 290.21 299.79 131.85 103.12 288.00 295.00 117.48 1.06 1.20 0.49 -1.33 -0.99 Matched[3942]
YLR196W PWP1 Protein with WD-40 repeats involved in rRNA processing; associates with trans-acting ribosome biogenesis factors; similar to beta-transducin superfamily Verified chr12:543970-545700 543970-545700 98.5% 346.45 196.38 221.00 163.55 13.48 15.24 271.41 192.28 14.36 1.00 0.78 0.06 -3.74 -4.80 Frag>80[3943,3944]
YLR197W SIK1 Essential evolutionarily-conserved nucleolar protein component of the box C/D snoRNP complexes that direct 2'-O-methylation of pre-rRNA during its maturation; overexpression causes spindle orientation defects Verified chr12:546099-547613 546099-547613 97.8% 2920.42 1601.98 2067.79 1993.53 309.86 200.50 2261.20 2030.66 255.18 8.35 8.24 1.06 -2.99 -3.71 Matched[3945]
YLR198C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene SIK1/YLR197W" Dubious chr12:547288-547647 547288-547647 94.0% 4579.45 2421.29 3089.43 2915.00 505.54 280.86 3500.37 3002.22 393.20 12.92 12.19 1.63 -2.93 -2.54 Covered/w/another[3945]
YLR199C PBA1 Protein involved in 20S proteasome assembly; forms a heterodimer with Add66p that binds to proteasome precursors; similar to human PAC1 constituent of the PAC1-PAC2 complex involved in proteasome assembly Verified chr12:547855-548771 547855-548679,548766-548771 99.0% 125.25 137.41 119.17 126.47 193.35 117.96 131.33 122.82 155.65 0.48 0.50 0.64 0.34 -0.74 Covered/w/another[3946]
YLR200W YKE2 "Subunit of the heterohexameric Gim/prefoldin protein complex involved in the folding of alpha-tubulin, beta-tubulin, and actin" Verified chr12:549014-549358 549014-549358 98.2% 445.65 377.77 383.67 321.69 321.69 233.15 411.71 352.68 277.42 1.52 1.43 1.15 -0.35 -0.80 Covered/w/another[3946]
YLR201C COQ9 Protein required for ubiquinone (coenzyme Q) biosynthesis and respiratory growth; localizes to the matrix face of the mitochondrial inner membrane in a large complex with ubiquinone biosynthetic enzymes Verified chr12:549513-550295 549513-550295 98.9% 196.37 273.89 215.75 236.42 373.36 244.17 235.13 226.09 308.77 0.87 0.92 1.28 0.45 0.20 Covered/w/another[3946]
YLR202C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YLR201C; ORF contains a putative intron" Dubious chr12:550196-550638 550196-550460,550577-550638 98.9% 126.76 132.94 111.30 111.30 244.24 139.12 129.85 111.30 191.68 0.48 0.45 0.79 0.78 -0.13 Covered/w/another[3946]
YLR203C MSS51 Nuclear encoded protein required for translation of COX1 mRNA; binds to Cox1 protein Verified chr12:550652-551962 550652-551962 98.7% 327.76 379.55 434.44 339.36 584.40 489.32 353.66 386.90 536.86 1.31 1.57 2.22 0.47 0.83 Covered/w/another[3946]
YLR204W QRI5 Mitochondrial protein of unknown function Verified chr12:552272-552607 552272-552607 97.9% 465.05 501.52 492.40 413.37 668.69 361.70 483.28 452.89 515.20 1.78 1.84 2.13 0.19 0.14 Matched[3947]
YLR205C HMX1 "ER localized, heme-binding peroxidase involved in the degradation of heme; does not exhibit heme oxygenase activity despite similarity to heme oxygenases; expression regulated by AFT1" Verified chr12:552726-553679 552726-553679 98.8% 32.89 23.34 39.26 13.79 143.24 77.45 28.12 26.53 110.34 0.10 0.11 0.46 2.06 1.64 Matched[3948]
YLR206W ENT2 Epsin-like protein required for endocytosis and actin patch assembly and functionally redundant with Ent1p; contains clathrin-binding motif at C-terminus Verified chr12:554580-556421 554580-556421 97.6% 379.45 356.64 397.26 360.53 600.89 468.47 368.05 378.89 534.68 1.36 1.54 2.22 0.50 0.86 Matched[3949]
YLR207W HRD3 "Resident protein of the ER membrane that plays a central role in ER-associated protein degradation (ERAD), forms HRD complex with Hrd1p and ERAD determinants that engages in lumen to cytosol communication and coordination of ERAD events" Verified chr12:556790-559291 556790-559291 98.6% 92.40 104.15 88.35 72.14 103.34 79.84 98.27 80.24 91.59 0.36 0.33 0.38 0.19 0.67 Frag>80[3950,3951]
YLR208W SEC13 "Component of both the Nup84 nuclear pore sub-complex and of the COPII complex (Sar1p, Sec13p, Sec16p, Sec23p, Sec24p, Sec31p, Sfb2p, and Sfb3p) which is important for the formation of ER to Golgi transport vesicles" Verified chr12:559553-560446 559553-560446 98.6% 1150.15 1008.37 1061.68 1054.87 910.82 746.35 1079.26 1058.27 828.58 3.98 4.30 3.43 -0.35 -0.31 Matched[3952]
YLR209C PNP1 "Purine nucleoside phosphorylase, specifically metabolizes inosine and guanosine nucleosides" Verified chr12:560799-561734 560799-561734 99.0% 233.08 213.66 221.21 143.52 242.79 141.36 223.37 182.37 192.08 0.82 0.74 0.80 0.07 0.08 Matched[3953]
YLR210W CLB4 "B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation" Verified chr12:562010-563392 562010-563392 98.7% 93.78 86.45 88.65 54.22 74.73 34.43 90.12 71.43 54.58 0.33 0.29 0.23 -0.39 0.11 Matched[3954]
YLR211C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLR211C is not an essential gene; ORF contains an intron Uncharacterized chr12:563794-564533 563794-564456,564516-564533 99.6% 73.68 110.52 78.10 61.89 156.21 89.89 92.10 70.00 123.05 0.34 0.28 0.51 0.81 0.33 Matched[3955]
YLR212C TUB4 "Gamma-tubulin, involved in nucleating microtubules from both the cytoplasmic and nuclear faces of the spindle pole body" Verified chr12:564862-566283 564862-566283 98.9% 118.03 121.59 108.08 91.01 54.04 30.58 119.81 99.55 42.31 0.44 0.40 0.18 -1.23 -0.74 Matched[3956]
YLR213C CRR1 "Putative glycoside hydrolase of the spore wall envelope; required for normal spore wall assembly, possibly for cross-linking between the glucan and chitosan layers; expressed during sporulation" Verified chr12:566656-567924 566656-567924 98.9% 39.03 31.06 31.86 23.90 16.73 30.27 35.05 27.88 23.50 0.13 0.11 0.10 -0.25 0.45
YLR214W FRE1 "Ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to uptake by transporters; expression induced by low copper and iron levels" Verified chr12:568569-570629 568569-570629 99.0% 352.52 57.85 224.06 82.86 80.90 35.30 205.18 153.46 58.10 0.76 0.62 0.24 -1.40 -1.16 Matched[3957]
YLR215C CDC123 Protein involved in nutritional control of the cell cycle; regulates abundance of the translation initiation factor eIF2; ortholog of human D123 protein Verified chr12:570778-571860 570778-571860 99.1% 77.34 65.22 79.20 49.38 41.93 29.82 71.28 64.29 35.87 0.26 0.26 0.15 -0.84 -0.64 Matched[3958]
YLR217W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene CPR6" Dubious chr12:572911-573234 572911-573234 99.6% 362.60 353.31 449.38 430.79 8798.55 8079.54 357.95 440.08 8439.05 1.32 1.79 34.97 4.26 0.00 Matched[3960]
YLR216C CPR6 "Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity" Verified chr12:572098-573213 572098-573213 99.2% 569.94 504.91 566.33 634.98 13367.96 10408.94 537.43 600.65 11888.45 1.98 2.44 49.26 4.31 3.37 Frag>80[3959,3960]
YLR218C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLR218C is not essential; mutants exhibit glycogen storage defects and growth defects on a non-fermentable carbon source Uncharacterized chr12:573468-573920 573468-573920 99.0% 173.96 194.03 176.19 189.57 321.16 140.51 184.00 182.88 230.83 0.68 0.74 0.96 0.34 -0.60 Covered/w/another[3961]
YLR219W MSC3 "Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; msc3 mutants are defective in directing meiotic recombination events to homologous chromatids; potential Cdc28p substrate" Verified chr12:574153-576339 574153-576339 98.5% 113.72 129.03 137.85 131.82 243.22 263.64 121.38 134.84 253.43 0.45 0.55 1.05 0.91 1.39 Covered/w/another[3961]
YLR220W CCC1 "Putative vacuolar Fe2+/Mn2+ transporter; suppresses respiratory deficit of yfh1 mutants, which lack the ortholog of mammalian frataxin, by preventing mitochondrial iron accumulation" Verified chr12:576827-577795 576827-577795 98.4% 217.17 293.76 295.86 232.91 294.81 226.61 255.46 264.38 260.71 0.94 1.07 1.08 -0.02 0.23 Covered/w/another[3961]
YLR221C RSA3 "Protein with a likely role in ribosomal maturation, required for accumulation of wild-type levels of large (60S) ribosomal subunits; binds to the helicase Dbp6p in pre-60S ribosomal particles in the nucleolus" Verified chr12:578364-579026 578364-579026 99.4% 411.23 233.69 227.62 209.41 42.49 9.10 322.46 218.51 25.80 1.19 0.89 0.11 -3.08 -3.13 Covered/w/another[3961]
YLR222C UTP13 "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" Verified chr12:579320-581773 579320-581773 99.3% 171.89 102.15 107.89 93.54 9.85 2.05 137.02 100.71 5.95 0.51 0.41 0.02 -4.08 -4.77 Matched[3962]
YLR222C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene IFH1" Dubious chr12:582008-582238 582008-582238 99.2% 135.35 144.08 104.78 34.93 52.39 39.29 139.71 69.86 45.84 0.52 0.28 0.19 -0.61 NaN Covered/w/another[3963]
YLR223C IFH1 "Essential protein with a highly acidic N-terminal domain; IFH1 exhibits genetic interactions with FHL1, overexpression interferes with silencing at telomeres and HM loci; potential Cdc28p substrate" Verified chr12:582235-585492 582235-585492 99.2% 220.27 216.87 120.97 118.18 67.75 84.46 218.57 119.57 76.11 0.81 0.49 0.32 -0.65 -0.05 Matched[3963]
YLR224W F-box protein and component of SCF ubiquitin ligase complexes involved in ubiquitin-dependent protein catabolism; readily monoubiquitinated in vitro by SCF-Ubc4 complexes; YLR224W is not an essential gene Uncharacterized chr12:586466-587575 586466-587575 98.8% 187.76 205.99 190.50 200.52 187.76 132.16 196.88 195.51 159.96 0.73 0.79 0.66 -0.29 0.23 Matched[3964]
YLR225C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLR225C is not an essential gene Uncharacterized chr12:587697-588920 587697-588920 99.3% 254.14 267.30 258.25 260.72 401.36 285.39 260.72 259.48 343.37 0.96 1.05 1.42 0.40 0.55 Matched[3965]
YLR226W BUR2 Cyclin for the Sgv1p (Bur1p) protein kinase; Sgv1p and Bur2p comprise a CDK-cyclin complex involved in transcriptional regulation through its phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II Verified chr12:589356-590543 589356-590543 98.9% 96.16 98.71 91.05 77.44 61.27 44.25 97.44 84.25 52.76 0.36 0.34 0.22 -0.68 -0.37 Matched[3966]
YLR227C ADY4 "Structural component of the meiotic outer plaque, which is a membrane-organizing center that assembles on the cytoplasmic face of the spindle pole body during meiosis II and triggers the formation of the prospore membrane" Verified chr12:590564-592045 590564-592045 99.3% 106.68 99.88 76.78 57.76 76.78 31.94 103.28 67.27 54.36 0.38 0.27 0.23 -0.31 -0.10 Frag<80[3967,3968]
YLR228C ECM22 "Sterol regulatory element binding protein, regulates transcription of the sterol biosynthetic genes ERG2 and ERG3; member of the fungus-specific Zn[2]-Cys[6] binuclear cluster family of transcription factors; homologous to Upc2p" Verified chr12:600021-602465 600021-602465 98.7% 99.84 98.59 99.84 87.00 83.27 83.27 99.22 93.42 83.27 0.37 0.38 0.35 -0.17 0.21 Matched[3972]
YLR230W Dubious open reading frame unlikely to encode a functional protein; overlaps 5' end of essential CDC42 gene which encodes a small Rho-like GTPase essential for establishment and maintenance of cell polarity Dubious chr12:604576-604881 604576-604881 99.2% 830.20 649.00 876.32 728.07 457.93 418.39 739.60 802.20 438.16 2.73 3.26 1.82 -0.87 0.39 Matched[3974]
YLR229C CDC42 "Small rho-like GTPase, essential for establishment and maintenance of cell polarity; mutants have defects in the organization of actin and septins" Verified chr12:604214-604789 604214-604789 98.9% 992.24 813.11 1043.17 890.38 593.59 460.12 902.68 966.78 526.85 3.33 3.92 2.18 -0.88 -0.53 Matched[3974]
YLR232W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene BNA5" Dubious chr12:606832-607179 606832-607179 99.4% 107.01 89.66 107.01 133.04 161.97 156.18 98.34 120.03 159.07 0.36 0.49 0.66 0.41 0.08 Covered/w/another[3975]
YLR231C BNA5 "Kynureninase, required for biosynthesis of nicotinic acid from tryptophan via kynurenine pathway" Verified chr12:605760-607121 605760-607121 99.1% 180.80 138.56 165.98 171.90 243.78 197.84 159.68 168.94 220.81 0.59 0.69 0.91 0.39 0.68 Matched[3975]
YLR233C EST1 "TLC1 RNA-associated factor involved in telomere length regulation as the recruitment subunit of the telomerase holoenzyme, has a possible role in activating Est2p-TLC1-RNA bound to the telomere" Verified chr12:607427-609526 607427-609526 97.6% 52.71 51.25 34.65 43.93 41.00 21.96 51.98 39.29 31.48 0.19 0.16 0.13 -0.32 0.05 Matched[3976]
YLR234W TOP3 "DNA Topoisomerase III, conserved protein that functions in a complex with Sgs1p and Rmi1p to relax single-stranded negatively-supercoiled DNA preferentially, involved in telomere stability and regulation of mitotic recombination" Verified chr12:609785-611755 609785-611755 98.2% 18.59 14.98 16.01 16.01 21.69 24.27 16.78 16.01 22.98 0.06 0.06 0.10 0.52 0.95 Matched[3977]
YLR235C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene TOP3" Dubious chr12:611534-611932 611534-611932 98.5% 20.35 15.26 17.81 12.72 45.79 40.70 17.81 15.26 43.24 0.07 0.06 0.18 1.50 0.10 Covered/w/another[3977]
YLR236C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr12:611796-612119 611796-612119 98.0% 37.80 18.90 28.35 12.60 53.54 40.94 28.35 20.47 47.24 0.10 0.08 0.20 1.21 0.73 Covered/w/another[3977]
YLR237W THI7 "Plasma membrane transporter responsible for the uptake of thiamine, member of the major facilitator superfamily of transporters; mutation of human ortholog causes thiamine-responsive megaloblastic anemia" Verified chr12:612369-614165 612369-614165 82.2% 172.60 136.73 147.55 91.38 91.38 60.92 154.66 119.47 76.15 0.57 0.48 0.32 -0.65 -0.26 Covered/w/another[3978]
YLR238W FAR10 "Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway different from the Far1p-dependent pathway; interacts with Far3p, Far7p, Far8p, Far9p, and Far11p; potential Cdc28p substrate" Verified chr12:614757-616193 614757-616193 98.6% 86.07 84.66 71.96 88.90 122.06 104.42 85.37 80.43 113.24 0.32 0.33 0.47 0.49 0.77 Covered/w/another[3978]
YLR239C LIP2 "Lipoyl ligase, involved in the modification of mitochondrial enzymes by the attachment of lipoic acid groups" Verified chr12:616334-617320 616334-617320 99.3% 126.53 136.73 125.51 107.14 178.57 134.69 131.63 116.33 156.63 0.49 0.47 0.65 0.43 0.53 Covered/w/another[3978]
YLR240W VPS34 Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate; forms membrane-associated signal transduction complex with Vps15p to regulate protein sorting; activated by the GTP-bound form of Gpa1p Verified chr12:617535-620162 617535-620162 98.9% 60.42 80.04 69.65 60.42 104.67 103.51 70.23 65.03 104.09 0.26 0.26 0.43 0.68 1.42 Matched[3979]
YLR241W "Putative protein of unknown function, may be involved in detoxification" Uncharacterized chr12:620475-622823 620475-622823 98.8% 152.89 221.36 164.09 153.75 194.66 212.32 187.13 158.92 203.49 0.69 0.65 0.84 0.36 0.91 Matched[3980]
YLR242C ARV1 Protein required for normal intracellular sterol distribution and for sphingolipid metabolism; similar to Nup120p and C. elegans R05H5.5 protein Verified chr12:622920-623885 622920-623885 99.1% 103.39 92.94 90.85 56.39 65.79 34.46 98.16 73.62 50.13 0.36 0.30 0.21 -0.55 -0.63 Matched[3981]
YLR243W Putative protein of unknown function; YLR243W is an essential gene Uncharacterized chr12:624205-625023 624205-625023 98.9% 181.43 138.23 134.53 123.42 53.07 33.32 159.83 128.97 43.20 0.59 0.52 0.18 -1.58 0.02 Matched[3982]
YLR244C MAP1 "Methionine aminopeptidase, catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map2p" Verified chr12:625170-626333 625170-626333 98.9% 1035.62 927.89 918.33 796.70 495.22 409.21 981.76 857.52 452.22 3.62 3.48 1.87 -0.92 -0.34 Matched[3983]
YLR245C CDD1 "Cytidine deaminase; catalyzes the modification of cytidine to uridine in vitro but native RNA substrates have not been identified, localizes to both the nucleus and cytoplasm" Verified chr12:626504-626932 626504-626932 98.9% 91.95 132.04 110.82 129.68 150.90 155.61 112.00 120.25 153.26 0.41 0.49 0.63 0.35 0.97 Covered/w/another[3984]
YLR246W ERF2 "Subunit of a palmitoyltransferase, composed of Erf2p and Shr5p, that adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; mutants partially mislocalize Ras2p to the vacuole" Verified chr12:627120-628199 627120-628199 98.8% 100.30 134.98 100.30 97.48 134.04 78.74 117.64 98.89 106.39 0.43 0.40 0.44 0.11 0.23 Matched[3984]
YLR247C Putative helicase; localized to mitochondria and the nucleus; YLR247C is not an essential gene; null mutant displays increased levels of spontaneous Rad52 foci Uncharacterized chr12:628686-633356 628686-633356 99.3% 59.30 54.34 43.99 38.81 89.49 74.61 56.82 41.40 82.05 0.21 0.17 0.34 0.99 0.95 Matched[3985]
YLR248W RCK2 Protein kinase involved in the response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations Verified chr12:634254-636086 634254-636086 98.6% 390.99 414.78 416.99 455.70 770.38 638.20 402.89 436.34 704.29 1.49 1.77 2.92 0.69 1.37 Covered[3986]
YLR249W YEF3 "Translational elongation factor 3, stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes by releasing EF-1 alpha from the ribosomal complex; contains two ABC cassettes; binds and hydrolyses ATP" Verified chr12:636782-639916 636782-639916 97.4% 7856.33 5602.30 6701.15 6306.15 967.83 884.32 6729.31 6503.65 926.08 24.84 26.40 3.84 -2.81 -3.22 Frag>80[3987,3988,3989]
YLR250W SSP120 Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern Verified chr12:640319-641023 640319-641023 98.5% 468.24 476.89 557.57 524.43 1082.00 734.78 472.57 541.00 908.39 1.74 2.20 3.76 0.75 0.92 Matched[3990]
YLR251W SYM1 Protein required for ethanol metabolism; induced by heat shock and localized to the inner mitochondrial membrane; homologous to mammalian peroxisomal membrane protein Mpv17 Verified chr12:641466-642059 641466-642059 98.8% 122.72 194.30 180.67 131.24 1600.45 894.82 158.51 155.95 1247.64 0.59 0.63 5.17 3.00 2.56 Matched[3992]
YLR252W "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the verified gene SYM1, a mitochondrial protein involved in ethanol metabolism" Dubious chr12:641959-642264 641959-642264 98.8% 132.25 254.58 175.23 188.46 2076.32 1110.90 193.42 181.84 1593.61 0.71 0.74 6.60 3.13 2.64 Matched[3992]
YLR253W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; transcription is periodic during the metabolic cycle; YLR253W is not an essential gene" Uncharacterized chr12:642629-644338 642629-644338 98.6% 138.74 141.11 168.98 139.33 117.40 64.63 139.93 154.16 91.01 0.52 0.63 0.38 -0.76 0.37 Matched[3993]
YLR254C NDL1 "Homolog of nuclear distribution factor NudE, NUDEL; interacts with Pac1p and regulates dynein targeting to microtubule plus ends" Verified chr12:644406-644975 644406-644975 99.2% 111.44 212.26 136.20 141.51 396.23 224.65 161.85 138.86 310.44 0.60 0.56 1.29 1.16 0.83 Matched[3994]
YLR255C "Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr12:645602-645955 645602-645955 99.1% 2.85 11.40 5.70 2.85 5.70 22.81 7.13 4.28 14.26 0.03 0.02 0.06 1.74 0.30
YLR256W HAP1 Zinc finger transcription factor involved in the complex regulation of gene expression in response to levels of heme and oxygen; the S288C sequence differs from other strain backgrounds due to a Ty1 insertion in the carboxy terminus Verified chr12:646417-650925 646417-650925 96.6% 254.48 474.06 248.97 207.86 235.19 274.01 364.27 228.42 254.60 1.34 0.93 1.05 0.16 0.62 Frag>80[3995,3996,3997]
YLR257W Putative protein of unknown function Uncharacterized chr12:658828-659793 658828-659793 98.4% 922.92 1015.52 1176.53 1223.89 2344.65 1413.31 969.22 1200.21 1878.98 3.58 4.87 7.79 0.65 -0.06 Matched[4000]
YLR258W GSY2 "Glycogen synthase, similar to Gsy1p; expression induced by glucose limitation, nitrogen starvation, heat shock, and stationary phase; activity regulated by cAMP-dependent, Snf1p and Pho85p kinases as well as by the Gac1p-Glc7p phosphatase" Verified chr12:660718-662835 660718-662835 98.7% 313.47 753.77 682.46 841.35 3446.28 2940.89 533.62 761.90 3193.59 1.97 3.09 13.23 2.07 1.64 Covered[4001]
YLR259C HSP60 Tetradecameric mitochondrial chaperonin required for ATP-dependent folding of precursor polypeptides and complex assembly; prevents aggregation and mediates protein refolding after heat shock; role in mtDNA transmission; phosphorylated Verified chr12:663286-665004 663286-665004 99.0% 1457.77 1192.77 1480.10 1482.45 8111.44 8085.59 1325.27 1481.27 8098.52 4.89 6.01 33.55 2.45 2.83 Matched[4002]
YLR260W LCB5 "Minor sphingoid long-chain base kinase, paralog of Lcb4p responsible for few percent of the total activity, possibly involved in synthesis of long-chain base phosphates, which function as signaling molecules" Verified chr12:665846-667909 665846-667909 98.4% 81.75 73.37 61.06 71.41 210.77 158.57 77.56 66.23 184.67 0.29 0.27 0.77 1.48 1.27 Covered[4003]
YLR261C VPS63 "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene YPT6; deletion causes a vacuolar protein sorting defect" Dubious chr12:668239-668565 668239-668565 99.6% 442.34 402.41 485.34 423.91 546.78 297.96 422.37 454.63 422.37 1.56 1.85 1.75 -0.11 -0.10 Matched[4004]
YLR262C YPT6 "GTPase, Ras-like GTP binding protein involved in the secretory pathway, required for fusion of endosome-derived vesicles with the late Golgi, maturation of the vacuolar carboxypeptidase Y; has similarity to the human GTPase, Rab6" Verified chr12:668246-668893 668246-668893 99.5% 389.15 317.83 386.05 348.84 434.11 262.02 353.49 367.44 348.06 1.30 1.49 1.44 -0.08 -0.13 Matched[4004]
YLR262C-A TMA7 "Protein of unknown that associates with ribosomes; null mutant exhibits translation defects, altered polyribosome profiles, and resistance to the translation inhibitor anisomcyin" Verified chr12:669470-669664 669470-669664 99.3% 2945.10 2485.25 2412.92 2345.75 2371.58 1431.22 2715.18 2379.33 1901.40 10.02 9.66 7.88 -0.32 -1.97 Matched[4005]
YLR263W RED1 "Protein component of the axial elements of the synaptonemal complex, involved in chromosome segregation during the first meiotic division; interacts with Hop1p; required for wild-type levels of Mek1p kinase activity" Verified chr12:670342-672825 670342-672825 98.8% 33.41 46.85 28.11 20.78 26.07 19.96 40.13 24.44 23.02 0.15 0.10 0.10 -0.09 0.53 Frag<80[4006,4007]
YLR264W RPS28B Protein component of the small (40S) ribosomal subunit; nearly identical to Rps28Ap and has similarity to rat S28 ribosomal protein Verified chr12:673133-673336 673133-673336 94.0% 4632.04 4209.52 3458.38 3004.56 1956.10 1783.96 4420.78 3231.47 1870.03 16.32 13.12 7.75 -0.79 -1.65 Matched[4008]
YLR264C-A Putative protein of unknown function Uncharacterized chr12:673830-673946 673830-673946 99.5% 5572.81 4628.27 3623.61 3280.14 2507.33 1897.67 5100.54 3451.88 2202.50 18.83 14.01 9.13 -0.65 NaN Matched[4008]
YLR265C NEJ1 Protein involved in regulation of nonhomologous end joining; repressed by MAT heterozygosity; associates with Lif1p and regulates its cellular distribution Verified chr12:674429-675457 674429-675457 99.2% 147.86 148.84 120.45 115.55 154.72 86.17 148.35 118.00 120.45 0.55 0.48 0.50 0.03 -0.24 Covered/w/another[4009]
YLR266C PDR8 "Transcription factor; targets include ATP-binding cassette (ABC) transporters, major facilitator superfamily transporters, and other genes involved in the pleiotropic drug resistance (PDR) phenomenon" Verified chr12:675621-677726 675621-677726 99.2% 110.14 148.93 108.23 93.38 134.09 61.78 129.54 100.81 97.93 0.48 0.41 0.41 -0.04 -2.11 Covered/w/another[4009]
YLR267W "Protein of unknown function, overproduction suppresses a pam1 slv3 double null mutation" Uncharacterized chr12:678214-679926 678214-679926 99.2% 26.49 36.50 35.32 27.67 65.93 35.91 31.50 31.50 50.92 0.12 0.13 0.21 0.69 0.91 Matched[4010]
YLR268W SEC22 "R-SNARE protein; assembles into SNARE complex with Bet1p, Bos1p and Sed5p; cycles between the ER and Golgi complex; involved in anterograde and retrograde transport between the ER and Golgi; synaptobrevin homolog" Verified chr12:680202-680846 680202-680846 98.9% 335.40 426.30 365.18 329.13 410.63 291.52 380.85 347.16 351.07 1.41 1.41 1.45 0.02 0.32 Matched[4011]
YLR270W DCS1 "Non-essential hydrolase involved in mRNA decapping, may function in a feedback mechanism to regulate deadenylation, contains pyrophosphatase activity and a HIT (histidine triad) motif; interacts with neutral trehalase Nth1p" Verified chr12:681188-682240 681188-682240 98.8% 332.55 476.71 440.19 458.45 1411.88 1329.22 404.63 449.32 1370.55 1.49 1.82 5.68 1.61 1.71 Matched[4012]
YLR269C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr12:680868-681218 680868-681218 99.1% 140.80 172.41 166.67 160.92 376.44 370.69 156.61 163.79 373.56 0.58 0.66 1.55 1.19 1.03 Covered/w/another[4012]
YLR271W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus and is induced in response to the DNA-damaging agent MMS Uncharacterized chr12:682739-683563 682739-683563 98.6% 82.40 103.31 82.40 111.91 313.60 166.03 92.85 97.16 239.82 0.34 0.39 0.99 1.30 0.80 Matched[4013]
YLR272C YCS4 "Non-SMC subunit of the condensin complex (Smc2p-Smc4p-Ycs4p-Brn1p-Ycg1p); required for establishment and maintenance of chromosome condensation, chromosome segregation, chromatin binding of condensin and silencing at the mating type locus" Verified chr12:683674-687204 683674-687204 99.3% 77.58 57.61 58.18 48.20 38.22 32.23 67.60 53.19 35.22 0.25 0.22 0.15 -0.59 -0.33 Frag>80[4014]
YLR273C PIG1 Putative targeting subunit for the type-1 protein phosphatase Glc7p that tethers it to the Gsy2p glycogen synthase Verified chr12:689085-691031 689085-691031 99.1% 27.47 25.91 35.24 31.61 78.77 53.38 26.69 33.43 66.08 0.10 0.14 0.27 0.98 1.07 Matched[4015]
YLR274W MCM5 "Component of the hexameric MCM complex, which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase" Verified chr12:691557-693884 691557-693884 98.6% 116.29 127.18 117.60 124.56 114.55 73.17 121.73 121.08 93.86 0.45 0.49 0.39 -0.37 0.01 Matched[4016]
YLR275W SMD2 "Core Sm protein Sm D2; part of heteroheptameric complex (with Smb1p, Smd1p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm D2" Verified chr12:694380-694802 694380-694384,694475-694802 98.6% 164.53 127.97 164.53 131.01 121.87 85.31 146.25 147.77 103.59 0.54 0.60 0.43 -0.51 -0.61 Matched[4017]
YLR276C DBP9 ATP-dependent RNA helicase of the DEAD-box family involved in biogenesis of the 60S ribosomal subunit Verified chr12:695048-696832 695048-696832 99.3% 389.28 187.31 248.24 202.54 27.64 2.82 288.29 225.39 15.23 1.06 0.91 0.06 -3.89 -3.71 Matched[4018]
YLR277C YSH1 "Putative endoribonuclease, subunit of the mRNA cleavage and polyadenylation specificity complex required for 3' processing of mRNAs" Verified chr12:697158-699497 697158-699497 99.2% 100.40 106.00 93.51 90.06 73.68 60.33 103.20 91.78 67.01 0.38 0.37 0.28 -0.45 -0.16 Matched[4019]
YLR278C Zinc-cluster protein; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; mutant shows moderate growth defect on caffeine; YLR278C is not an essential gene Uncharacterized chr12:700001-704026 700001-704026 98.0% 117.62 130.80 101.40 97.85 95.06 114.58 124.21 99.62 104.82 0.46 0.40 0.43 0.07 0.65 Frag<80[4020,4021]
YLR279W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr12:704311-704700 704311-704700 98.5% 67.69 111.95 80.71 72.90 91.13 44.26 89.82 76.81 67.69 0.33 0.31 0.28 -0.18 0.17 Covered/w/another[4022]
YLR280C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr12:704485-704835 704485-704835 98.5% 66.50 78.06 80.95 49.15 78.06 49.15 72.28 65.05 63.61 0.27 0.26 0.26 -0.03 -0.64 Covered/w/another[4022]
YLR281C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YLR281C is not an essential gene Uncharacterized chr12:704495-704962 704495-704962 98.7% 67.12 77.94 75.78 49.80 84.44 51.96 72.53 62.79 68.20 0.27 0.25 0.28 0.12 1.49 Covered/w/another[4022]
YLR283W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YLR283W is not an essential gene Uncharacterized chr12:705188-706132 705188-706132 99.0% 80.21 141.16 88.76 93.04 192.50 137.96 110.69 90.90 165.23 0.41 0.37 0.68 0.86 0.57 Covered/w/another[4022]
YLR282C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr12:705073-705414 705073-705414 98.8% 47.34 68.06 53.26 35.51 94.69 82.85 57.70 44.38 88.77 0.21 0.18 0.37 1.00 -0.01 Covered/w/another[4022]
YLR284C ECI1 "Peroxisomal delta3,delta2-enoyl-CoA isomerase, hexameric protein that converts 3-hexenoyl-CoA to trans-2-hexenoyl-CoA, essential for the beta-oxidation of unsaturated fatty acids, oleate-induced" Verified chr12:706200-707042 706200-707042 99.3% 72.85 81.21 65.69 74.05 127.79 71.66 77.03 69.87 99.73 0.28 0.28 0.41 0.51 0.17 Covered/w/another[4022]
YLR285W NNT1 "Putative nicotinamide N-methyltransferase, has a role in rDNA silencing and in lifespan determination" Verified chr12:707362-708147 707362-708147 98.8% 366.99 242.09 316.77 242.09 181.56 145.51 304.54 279.43 163.54 1.12 1.13 0.68 -0.77 -0.37 Matched[4023]
YLR285C-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr12:708170-708340 708170-708340 98.8% 947.21 728.17 645.29 491.37 432.17 219.04 837.69 568.33 325.60 3.09 2.31 1.35 -0.80 NaN Covered/w/another[4023]
YLR286W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene CTS1" Dubious chr12:708564-708698 708564-708698 99.3% 3461.61 3737.64 3103.51 2820.02 1917.31 1283.18 3599.63 2961.77 1600.25 13.29 12.02 6.63 -0.89 NaN Covered/w/another[4024]
YLR286C CTS1 "Endochitinase, required for cell separation after mitosis; transcriptional activation during late G and early M cell cycle phases is mediated by transcription factor Ace2p" Verified chr12:708450-710138 708450-710138 98.6% 2738.93 2966.52 2676.48 2384.63 1235.85 1107.34 2852.72 2530.55 1171.60 10.53 10.27 4.85 -1.11 -0.78 Matched[4024]
YLR287C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLR287C is not an essential gene Uncharacterized chr12:710993-712060 710993-712060 99.4% 150.79 125.34 115.92 92.36 39.58 32.99 138.07 104.14 36.28 0.51 0.42 0.15 -1.52 -1.50 Matched[4026]
YLR287C-A RPS30A Protein component of the small (40S) ribosomal subunit; nearly identical to Rps30Bp and has similarity to rat S30 ribosomal protein Verified chr12:712539-713160 712539-712727,713158-713160 55.6% 11171.28 10749.90 10628.17 8830.28 7294.58 5206.40 10960.59 9729.22 6250.49 40.46 39.49 25.90 -0.64 -2.31 Matched[4027]
YLR288C MEC3 "DNA damage and meiotic pachytene checkpoint protein; subunit of a heterotrimeric complex (Rad17p-Mec3p-Ddc1p) that forms a sliding clamp, loaded onto partial duplex DNA by a clamp loader complex; homolog of human and S. pombe Hus1" Verified chr12:713482-714906 713482-714906 99.2% 61.54 62.96 50.93 38.91 76.40 50.22 62.25 44.92 63.31 0.23 0.18 0.26 0.50 0.63 Matched[4028]
YLR289W GUF1 "Mitochondrial GTPase of unknown function, similar to E. coli elongation factor-type GTP-binding protein LepA and to LK1236.1 from Caenorhabditis elegans" Verified chr12:715091-717028 715091-717028 98.6% 51.81 45.01 53.91 46.06 86.88 65.94 48.41 49.98 76.41 0.18 0.20 0.32 0.61 0.60 Matched[4029]
YLR290C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YLR290C is not an essential gene" Uncharacterized chr12:717147-717980 717147-717980 99.2% 227.32 290.19 264.80 241.83 532.02 336.14 258.75 253.31 434.08 0.96 1.03 1.80 0.78 0.52 Matched[4030]
YLR291C GCD7 "Beta subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression" Verified chr12:718319-719464 718319-719464 98.9% 309.55 255.75 288.38 268.10 161.39 144.63 282.65 278.24 153.01 1.04 1.13 0.63 -0.86 -0.39 Frag>80[4031,4032]
YLR292C SEC72 "Non-essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER" Verified chr12:719791-720372 719791-720372 99.2% 514.32 483.15 516.05 472.76 465.83 266.69 498.74 494.41 366.26 1.84 2.01 1.52 -0.43 -0.66 Matched[4033]
YLR293C GSP1 "GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RNA processing and transport; regulated by Prp20p, Rna1p, Yrb1p, Yrb2p, Yrp4p, Yrb30p, Cse1p and Kap95p; yeast Gsp2p homolog" Verified chr12:720773-721432 720773-721432 95.8% 3018.78 2538.05 2541.21 2438.43 1378.93 1062.66 2778.41 2489.82 1220.79 10.26 10.11 5.06 -1.03 -0.71 Frag>80[4034,4035,4036]
YLR294C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene ATP14" Dubious chr12:721703-722032 721703-722032 99.0% 646.00 584.77 655.19 851.13 1145.04 823.57 615.38 753.16 984.31 2.27 3.06 4.08 0.39 0.33 Matched[4036]
YLR295C ATP14 "Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis" Verified chr12:722001-722375 722001-722375 98.9% 649.67 695.50 811.41 938.11 1318.21 1002.81 672.58 874.76 1160.51 2.48 3.55 4.81 0.41 0.31 Matched[4037]
YLR296W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr12:722980-723306 722980-723306 99.0% 0.00 12.35 3.09 12.35 3.09 3.09 6.18 7.72 3.09 0.02 0.03 0.01 -1.32 -0.08
YLR297W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YLR297W is not an essential gene Uncharacterized chr12:724046-724435 724046-724435 98.7% 98.68 161.00 88.29 54.53 384.33 199.96 129.84 71.41 292.14 0.48 0.29 1.21 2.03 0.63 Covered/w/another[4039]
YLR298C YHC1 "Component of the U1 snRNP complex required for pre-mRNA splicing; putative ortholog of human U1C protein, which is involved in formation of a complex between U1 snRNP and the pre-mRNA 5' splice site" Verified chr12:724723-725418 724723-725418 99.2% 196.95 159.30 170.88 186.81 270.80 183.91 178.12 178.85 227.36 0.66 0.73 0.94 0.35 0.60 Matched[4039]
YLR299W ECM38 "Gamma-glutamyltranspeptidase, major glutathione-degrading enzyme; expression induced mainly by nitrogen starvation" Verified chr12:726071-728053 726071-728053 98.6% 142.73 162.68 145.28 118.68 146.31 102.82 152.70 131.98 124.57 0.56 0.54 0.52 -0.08 0.33 Matched[4040]
YLR299C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene ECM38" Dubious chr12:727913-728005 727913-728005 97.6% 231.40 198.35 231.40 198.35 396.69 176.31 214.88 214.88 286.50 0.79 0.87 1.19 0.42 NaN Covered/w/another[4040]
YLR300W EXG1 "Major exo-1,3-beta-glucanase of the cell wall, involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes" Verified chr12:728957-730303 728957-730303 98.8% 2187.35 2253.45 1783.23 1401.65 766.17 507.03 2220.40 1592.44 636.60 8.20 6.46 2.64 -1.32 -0.69 Matched[4041]
YLR301W Protein of unknown function that interacts with Sec72p Uncharacterized chr12:730827-731561 730827-731561 98.7% 897.05 792.33 788.20 773.04 1473.04 901.19 844.69 780.62 1187.12 3.12 3.17 4.92 0.60 0.32 Matched[4042]
YLR303W MET17 "Methionine and cysteine synthase (O-acetyl homoserine-O-acetyl serine sulfhydrylase), required for sulfur amino acid synthesis" Verified chr12:732544-733878 732544-733878 99.0% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.01
YLR302C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr12:732193-732555 732193-732555 98.7% 0.00 0.00 2.79 2.79 0.00 0.00 0.00 2.79 0.00 0.00 0.01 0.00 -Inf -0.45
YLR304C ACO1 "Aconitase, required for the tricarboxylic acid (TCA) cycle and also independently required for mitochondrial genome maintenance; phosphorylated; component of the mitochondrial nucleoid; mutation leads to glutamate auxotrophy" Verified chr12:735214-737550 735214-737550 98.9% 944.53 1634.34 1059.14 1349.77 1386.96 1604.93 1289.44 1204.45 1495.95 4.76 4.89 6.20 0.31 0.31 Frag>80[4043,4044]
YLR305C STT4 "Phosphatidylinositol-4-kinase that functions in the Pkc1p protein kinase pathway; required for normal vacuole morphology, cell wall integrity, and actin cytoskeleton organization" Verified chr12:738163-743865 738163-743865 98.9% 120.35 117.87 102.09 84.01 60.09 77.81 119.11 93.05 68.95 0.44 0.38 0.29 -0.43 0.18 Frag>80[4045,4046,4047,4048]
YLR306W UBC12 "Enzyme that mediates the conjugation of Rub1p, a ubiquitin-like protein, to other proteins; related to E2 ubiquitin-conjugating enzymes" Verified chr12:744153-744853 744153-744155,744290-744853 98.8% 133.87 182.06 91.03 121.37 189.20 116.02 157.97 106.20 152.61 0.58 0.43 0.63 0.52 0.45 Frag>80[4048,4049]
YLR307W CDA1 "Chitin deacetylase, together with Cda2p involved in the biosynthesis ascospore wall component, chitosan; required for proper rigidity of the ascospore wall" Verified chr12:745622-746527 745622-746527 98.7% 14.54 5.59 10.06 4.47 21.24 15.65 10.06 7.27 18.45 0.04 0.03 0.08 1.34 0.86
YLR307C-A Putative protein of unknown function Uncharacterized chr12:746850-747113 746850-747113 99.3% 3.81 0.00 0.00 0.00 15.25 3.81 1.91 0.00 9.53 0.01 0.00 0.04 Inf NaN
YLR308W CDA2 "Chitin deacetylase, together with Cda1p involved in the biosynthesis ascospore wall component, chitosan; required for proper rigidity of the ascospore wall" Verified chr12:747939-748877 747939-748877 98.9% 1.08 0.00 1.08 1.08 4.31 0.00 0.54 1.08 2.15 0.00 0.00 0.01 1.00 0.69 Overlap[4050]
YLR309C IMH1 "Protein involved in vesicular transport, mediates transport between an endosomal compartment and the Golgi, contains a Golgi-localization (GRIP) domain that interacts with activated Arl1p-GTP to localize Imh1p to the Golgi" Verified chr12:749036-751771 749036-751771 99.5% 252.64 231.71 206.00 216.65 321.31 283.12 242.17 211.33 302.21 0.89 0.86 1.25 0.52 0.65 Matched[4050]
YLR310C CDC25 Membrane bound guanine nucleotide exchange factor (GEF or GDP-release factor); indirectly regulates adenylate cyclase through activation of Ras1p and Ras2p by stimulating the exchange of GDP for GTP; required for progression through G1 Verified chr12:752226-756995 752226-756995 99.1% 164.34 162.22 157.99 162.01 80.79 113.79 163.28 160.00 97.29 0.60 0.65 0.40 -0.72 0.16 Covered/w/another[4051]
YLR311C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr12:757267-757614 757267-757614 98.6% 8.74 5.83 20.40 26.22 104.89 20.40 7.28 23.31 62.64 0.03 0.09 0.26 1.43 1.04 Covered/w/another[4051]
YLR312C Protein of unknown function; null mutant quiescent and non-quiescent cells exhibit reduced reproductive capacity Uncharacterized chr12:757639-758835 757639-758835 99.2% 22.73 16.84 33.67 22.73 80.81 37.04 19.78 28.20 58.92 0.07 0.11 0.24 1.06 0.87 Covered/w/another[4051]
YLR312W-A MRPL15 Mitochondrial ribosomal protein of the large subunit Verified chr12:759482-760243 759482-760243 98.7% 228.75 206.14 254.02 199.49 231.41 151.61 217.44 226.75 191.51 0.80 0.92 0.79 -0.24 -0.54 Matched[4052]
YLR313C SPH1 "Protein involved in shmoo formation and bipolar bud site selection; homologous to Spa2p, localizes to sites of polarized growth in a cell cycle dependent- and Spa2p-dependent manner, interacts with MAPKKs Mkk1p, Mkk2p, and Ste7p" Verified chr12:760357-762342 760357-762342 99.1% 58.40 61.45 50.28 41.64 35.55 27.93 59.93 45.96 31.74 0.22 0.19 0.13 -0.53 -0.30 Matched[4053]
YLR314C CDC3 "Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM" Verified chr12:762575-764137 762575-764137 99.3% 570.78 497.34 626.19 574.65 631.34 521.82 534.06 600.42 576.58 1.97 2.44 2.39 -0.06 0.25 Matched[4054]
YLR315W NKP2 "Non-essential kinetochore protein, subunit of the Ctf19 central kinetochore complex (Ctf19p-Mcm21p-Okp1p-Mcm22p-Mcm16p-Ctf3p-Chl4p-Mcm19p-Nkp1p-Nkp2p-Ame1p-Mtw1p)" Verified chr12:764808-765269 764808-765269 98.6% 76.82 57.07 28.53 43.90 61.46 41.70 66.95 36.22 51.58 0.25 0.15 0.21 0.51 0.47 Matched[4055]
YLR317W Dubious open reading frame; may be part of a bicistronic transcript with NKP2/YLR315W; overlaps the verified ORF TAD3/YLR316C Dubious chr12:765655-766089 765655-766089 99.2% 143.62 192.26 155.20 113.50 159.83 64.86 167.94 134.35 112.34 0.62 0.55 0.47 -0.26 0.62 Matched[4056]
YLR316C TAD3 "Subunit of tRNA-specific adenosine-34 deaminase, forms a heterodimer with Tad2p that converts adenosine to inosine at the wobble position of several tRNAs" Verified chr12:765266-766358 765266-766073,766130-766181,766250-766358 99.2% 151.96 162.37 137.39 106.16 136.35 67.65 157.16 121.77 102.00 0.58 0.49 0.42 -0.26 -0.92 Matched[4056]
YLR318W EST2 "Reverse transcriptase subunit of the telomerase holoenzyme, essential for telomerase core catalytic activity, involved in other aspects of telomerase assembly and function; mutations in human homolog are associated with aplastic anemia" Verified chr12:766542-769196 766542-769196 99.2% 36.08 35.70 26.20 20.13 19.37 15.57 35.89 23.17 17.47 0.13 0.09 0.07 -0.41 -1.02 Matched[4057]
YLR319C BUD6 "Actin- and formin-interacting protein, involved in actin cable nucleation and polarized cell growth; isolated as bipolar budding mutant; potential Cdc28p substrate" Verified chr12:769318-771684 769318-771684 99.3% 104.26 108.94 91.92 82.56 62.56 49.37 106.60 87.24 55.96 0.39 0.35 0.23 -0.64 -0.39 Matched[4058]
YLR320W MMS22 Protein involved in resistance to ionizing radiation; acts with Mms1p in a repair pathway that may be involved in resolving replication intermediates or preventing the damage caused by blocked replication forks Verified chr12:771940-776304 771940-776304 98.9% 37.06 33.36 33.82 19.46 24.56 28.03 35.21 26.64 26.29 0.13 0.11 0.11 -0.02 0.13 Frag<80[4059]
YLR322W VPS65 "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 75% of ORF overlaps the verified gene SFH1; deletion causes a vacuolar protein sorting defect" Dubious chr12:777628-777942 777628-777942 99.4% 137.38 121.41 111.82 83.07 44.73 54.31 129.39 97.44 49.52 0.48 0.40 0.21 -0.98 -0.05 Covered/w/another[4060]
YLR321C SFH1 Component of the RSC chromatin remodeling complex; essential gene required for cell cycle progressionand maintenance of proper ploidy; phosphorylated in the G1 phase of the cell cycle; Snf5p paralog Verified chr12:776584-777864 776584-777864 99.2% 221.99 197.59 183.42 160.59 123.59 100.76 209.79 172.00 112.18 0.77 0.70 0.46 -0.62 -0.11 Covered/w/another[4060]
YLR323C CWC24 "Essential protein, component of a complex containing Cef1p; has similarity to S. pombe Cwf24p" Verified chr12:778173-778952 778173-778952 99.3% 64.54 65.83 46.47 45.18 37.44 18.07 65.19 45.83 27.75 0.24 0.19 0.11 -0.72 -0.14 Covered/w/another[4060]
YLR324W PEX30 "Peroxisomal integral membrane protein, involved in negative regulation of peroxisome number; partially functionally redundant with Pex31p; genetic interactions suggest action at a step downstream of steps mediated by Pex28p and Pex29p" Verified chr12:779215-780786 779215-780786 98.4% 131.29 155.86 141.63 146.81 278.09 236.70 143.57 144.22 257.40 0.53 0.59 1.07 0.84 0.93 Matched[4061]
YLR325C RPL38 "Protein component of the large (60S) ribosomal subunit, has similarity to rat L38 ribosomal protein" Verified chr12:781143-781379 781143-781379 99.2% 11162.30 8411.06 9291.28 8687.46 2734.23 2661.94 9786.68 8989.37 2698.09 36.13 36.49 11.18 -1.74 -4.27 Matched[4062]
YLR326W Hypothetical protein Uncharacterized chr12:782174-782896 782174-782896 98.4% 61.86 123.71 77.32 64.67 154.64 84.35 92.78 70.99 119.49 0.34 0.29 0.50 0.75 0.94 Matched[4063]
YLR327C TMA10 Protein of unknown function that associates with ribosomes Verified chr12:783127-783387 783127-783387 99.2% 115.90 204.76 610.43 567.93 17532.52 6992.92 160.33 589.18 12262.72 0.59 2.39 50.81 4.38 3.00 Matched[4064]
YLR328W NMA1 "Nicotinic acid mononucleotide adenylyltransferase, involved in NAD(+) salvage pathway" Verified chr12:784913-786118 784913-786118 98.9% 169.42 114.06 139.22 127.48 112.38 84.71 141.74 133.35 98.55 0.52 0.54 0.41 -0.44 -0.12 Matched[4065]
YLR329W REC102 Protein involved in early stages of meiotic recombination; required for chromosome synapsis; forms a complex with Rec104p and Spo11p necessary during the initiation of recombination Verified chr12:786442-787333 786442-786615,786713-787333 99.0% 13.98 13.98 10.16 7.62 25.41 21.60 13.98 8.89 23.51 0.05 0.04 0.10 1.40 0.09 Frag<80[4066]
YLR330W CHS5 "Protein involved in export from the Golgi to plasma membrane; involved in chitin biosynthesis through its role in Chs3p localization; interacts with Arf1p, Bch1p, Fmp50p, Bud7p, and Chs6p" Verified chr12:787664-789679 787664-789679 94.1% 546.66 547.19 553.52 580.40 611.51 492.37 546.93 566.96 551.94 2.02 2.30 2.29 -0.04 0.10 Frag>80[4067,4068]
YLR332W MID2 "O-glycosylated plasma membrane protein that acts as a sensor for cell wall integrity signaling and activates the pathway; interacts with Rom2p, a guanine nucleotide exchange factor for Rho1p, and with cell integrity pathway protein Zeo1p" Verified chr12:790676-791806 790676-791806 99.2% 263.06 209.56 243.44 223.82 230.07 171.21 236.31 233.63 200.64 0.87 0.95 0.83 -0.22 0.56 Frag>80[4069,4070,4071]
YLR331C JIP3 "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene MID2" Dubious chr12:790669-791046 790669-791046 99.6% 284.32 204.61 255.09 225.86 233.84 191.32 244.46 240.48 212.58 0.90 0.98 0.88 -0.18 0.31 Matched[4069]
YLR333C RPS25B Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Ap and has similarity to rat S25 ribosomal protein Verified chr12:795573-796336 795573-795912,796335-796336 76.0% 3794.13 3163.06 3039.92 2543.53 1408.37 854.26 3478.60 2791.73 1131.31 12.84 11.33 4.69 -1.30 -1.39 Matched[4075]
YLR334C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps a stand-alone long terminal repeat sequence whose presence indicates a retrotransposition event occurred here" Dubious chr12:796698-797078 796698-797078 85.3% 3.08 0.00 0.00 0.00 9.23 0.00 1.54 0.00 4.61 0.01 0.00 0.02 Inf -0.06
YLR335W NUP2 "Nucleoporin involved in nucleocytoplasmic transport, binds to either the nucleoplasmic or cytoplasmic faces of the nuclear pore complex depending on Ran-GTP levels; also has a role in chromatin organization" Verified chr12:797430-799592 797430-799592 98.6% 440.55 383.37 399.77 377.28 269.48 268.08 411.96 388.53 268.78 1.52 1.58 1.11 -0.53 -0.02 Matched[4076]
YLR336C SGD1 Essential nuclear protein with a possible role in the osmoregulatory glycerol response; interacts with phospholipase C (Plc1p); putative homolog of human NOM1 which is implicated in acute myeloid leukemia Verified chr12:799697-802396 799697-802396 99.4% 93.94 65.61 49.95 44.36 17.52 11.93 79.77 47.16 14.72 0.29 0.19 0.06 -1.68 -1.32 Matched[4077]
YLR338W OPI9 "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF VRP1/YLR337C" Dubious chr12:804346-805203 804346-805203 98.1% 131.93 159.26 171.15 135.49 215.12 373.20 145.60 153.32 294.16 0.54 0.62 1.22 0.94 0.82 Covered/w/another[4078]
YLR337C VRP1 Proline-rich actin-associated protein involved in cytoskeletal organization and cytokinesis; related to mammalian Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP) Verified chr12:802653-805106 802653-805106 98.0% 202.51 244.51 252.41 199.60 359.69 499.83 223.51 226.00 429.76 0.83 0.92 1.78 0.93 1.29 Matched[4078]
YLR340W RPP0 "Conserved ribosomal protein P0 similar to rat P0, human P0, and E. coli L10e; shown to be phosphorylated on serine 302" Verified chr12:805887-806825 805887-806825 97.5% 12964.68 11638.38 11746.54 10210.49 4638.75 3829.21 12301.53 10978.51 4233.98 45.41 44.56 17.54 -1.37 -1.96 Matched[4079]
YLR339C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the essential gene RPP0" Dubious chr12:805784-806335 805784-806335 98.6% 9278.24 8394.86 8550.96 7673.09 3287.42 2890.73 8836.55 8112.03 3089.07 32.62 32.93 12.80 -1.39 -0.03 Matched[4079]
YLR341W SPO77 "Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensable for both nuclear divisions during meiosis" Verified chr12:807385-808818 807385-808818 99.0% 16.21 10.57 13.39 7.75 33.12 18.32 13.39 10.57 25.72 0.05 0.04 0.11 1.28 -0.82 Frag<80[4080]
YLR342W FKS1 "Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alternate catalytic subunit Gsc2p; binds to regulatory subunit Rho1p; involved in cell wall synthesis and maintenance; localizes to sites of cell wall remodeling" Verified chr12:809997-815627 809997-815627 96.8% 888.03 833.72 770.97 734.09 183.29 300.17 860.87 752.53 241.73 3.18 3.05 1.00 -1.64 -1.06 Frag>80[4081,4082,4083]
YLR342W-A Putative protein of unknown function Uncharacterized chr12:815810-815983 815810-815983 99.2% 423.09 446.27 208.65 237.62 52.16 52.16 434.68 223.13 52.16 1.60 0.91 0.22 -2.10 NaN Matched[4083]
YLR343W GAS2 "1,3-beta-glucanosyltransferase, involved with Gas4p in spore wall assembly; has similarity to Gas1p" Verified chr12:816094-817761 816094-817761 98.8% 199.11 272.56 139.62 88.02 46.14 19.43 235.84 113.82 32.78 0.87 0.46 0.14 -1.80 -1.08 Frag>80[4083,4084,4085]
YLR344W RPL26A "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Bp and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA" Verified chr12:819312-820142 819312-819330,819778-820142 71.7% 4044.21 3168.51 3386.53 2565.33 1111.88 624.98 3606.36 2975.93 868.43 13.31 12.08 3.60 -1.78 -2.54 Matched[4086]
YLR345W "Similar to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase enzymes responsible for the metabolism of fructoso-2,6-bisphosphate; mRNA expression is repressed by the Rfx1p-Tup1p-Ssn6p repressor complex; YLR345W is not an essential gene" Uncharacterized chr12:820511-822040 820511-822040 98.7% 126.46 217.83 217.16 253.58 471.41 309.86 172.14 235.37 390.63 0.64 0.96 1.62 0.73 0.90 Matched[4087]
YLR346C "Putative protein of unknown function found in mitochondria; expression is regulated by transcription factors involved in pleiotropic drug resistance, Pdr1p and Yrr1p; YLR346C is not an essential gene" Uncharacterized chr12:822287-822592 822287-822592 99.4% 39.44 82.16 88.73 39.44 167.60 95.30 60.80 64.08 131.45 0.22 0.26 0.54 1.04 0.58 Matched[4088]
YLR347W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified ORF KAP95/YLR347C" Dubious chr12:824788-824928 824788-824928 98.1% 252.94 130.08 267.39 173.44 274.62 361.34 191.51 220.42 317.98 0.71 0.89 1.32 0.53 NaN Covered/w/another[4090]
YLR347C KAP95 "Karyopherin beta, forms a dimeric complex with Srp1p (Kap60p) that mediates nuclear import of cargo proteins via a nuclear localization signal (NLS), interacts with nucleoporins to guide transport across the nuclear pore complex" Verified chr12:823827-826412 823827-826412 98.9% 231.46 175.94 187.28 160.69 231.85 283.46 203.70 173.99 257.66 0.75 0.71 1.07 0.57 1.17 Matched[4090]
YLR349W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified ORF DIC1/YLR348C" Dubious chr12:827520-828026 827520-828026 98.9% 167.50 199.40 229.31 175.47 346.96 245.26 183.45 202.39 296.11 0.68 0.82 1.23 0.55 0.36 Frag>80[4091,4092,4093]
YLR348C DIC1 "Mitochondrial dicarboxylate carrier, integral membrane protein, catalyzes a dicarboxylate-phosphate exchange across the inner mitochondrial membrane, transports cytoplasmic dicarboxylates into the mitochondrial matrix" Verified chr12:826976-827872 826976-827872 98.8% 270.82 313.70 368.99 267.43 580.00 388.17 292.26 318.21 484.08 1.08 1.29 2.01 0.61 0.49 Matched[4091]
YLR350W ORM2 "Evolutionarily conserved protein with similarity to Orm1p, required for resistance to agents that induce the unfolded protein response; human ortholog is located in the endoplasmic reticulum" Verified chr12:828729-829379 828729-829379 98.8% 329.66 307.89 416.74 329.66 945.45 673.32 318.78 373.20 809.38 1.18 1.51 3.35 1.12 1.15 Matched[4094]
YLR351C NIT3 "Nit protein, one of two proteins in S. cerevisiae with similarity to the Nit domain of NitFhit from fly and worm and to the mouse and human Nit protein which interacts with the Fhit tumor suppressor; nitrilase superfamily member" Verified chr12:829488-830363 829488-830363 99.0% 527.05 574.34 506.30 501.68 375.97 276.79 550.70 503.99 326.38 2.03 2.05 1.35 -0.63 -0.05 Matched[4095]
YLR352W Putative protein of unknown function with similarity to F-box proteins; interacts with Skp1p and Cdc53p; YLR352W is not an essential gene Uncharacterized chr12:831115-833538 831115-833538 99.0% 70.81 68.73 59.57 51.23 88.72 94.14 69.77 55.40 91.43 0.26 0.22 0.38 0.72 1.38 Covered/w/another[4096]
YLR353W BUD8 "Protein involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern, and bud at the proximal pole" Verified chr12:834351-836162 834351-836162 98.5% 140.03 151.79 140.59 107.54 95.78 84.02 145.91 124.07 89.90 0.54 0.50 0.37 -0.46 -0.38 Covered/w/another[4096]
YLR354C TAL1 "Transaldolase, enzyme in the non-oxidative pentose phosphate pathway; converts sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate to erythrose 4-phosphate and fructose 6-phosphate" Verified chr12:836349-837356 836349-837356 98.8% 2683.62 3246.85 2645.47 2595.27 2057.14 1710.77 2965.24 2620.37 1883.96 10.95 10.64 7.81 -0.48 -0.03 Frag>80[4097,4098,4099,4100]
YLR355C ILV5 "Acetohydroxyacid reductoisomerase, mitochondrial protein involved in branched-chain amino acid biosynthesis, also required for maintenance of wild-type mitochondrial DNA and found in mitochondrial nucleoids" Verified chr12:838065-839252 838065-839252 98.6% 3618.49 3416.13 3638.98 2297.63 498.63 191.26 3517.31 2968.30 344.94 12.98 12.05 1.43 -3.11 -3.31 Matched[4101]
YLR356W Putative protein of unknown function with similarity to SCM4; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YLR356W is not an essential gene Uncharacterized chr12:840320-840913 840320-840913 99.0% 214.27 323.11 251.68 311.20 719.34 734.64 268.69 281.44 726.99 0.99 1.14 3.01 1.37 1.40 Matched[4102]
YLR357W RSC2 Component of the RSC chromatin remodeling complex; required for expression of mid-late sporulation-specific genes; involved in telomere maintenance Verified chr12:841330-843999 841330-843999 98.7% 185.95 171.91 147.62 138.13 74.76 72.86 178.93 142.88 73.81 0.66 0.58 0.31 -0.95 -0.27 Matched[4103]
YLR358C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF RSC2/YLR357W" Dubious chr12:843486-844049 843486-844049 98.5% 318.61 244.81 230.41 203.41 133.20 117.00 281.71 216.91 125.10 1.04 0.88 0.52 -0.79 -0.58 Covered/w/another[4103]
YLR359W ADE13 "Adenylosuccinate lyase, catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway; expression is repressed by adenine and activated by Bas1p and Pho2p; mutations in human ortholog ADSL cause adenylosuccinase deficiency" Verified chr12:844281-845729 844281-845729 98.8% 3879.85 2951.45 3625.57 3191.06 523.93 260.57 3415.65 3408.31 392.25 12.61 13.83 1.63 -3.12 -3.34 Matched[4104]
YLR360W VPS38 Part of a Vps34p phosphatidylinositol 3-kinase complex that functions in carboxypeptidase Y (CPY) sorting; binds Vps30p and Vps34p to promote production of phosphatidylinositol 3-phosphate (PtdIns3P) which stimulates kinase activity Verified chr12:846102-847421 846102-847421 99.0% 117.07 137.73 115.54 117.07 255.57 156.10 127.40 116.31 205.83 0.47 0.47 0.85 0.82 0.53 Matched[4105]
YLR361C DCR2 "Phosphoesterase involved in downregulation of the unfolded protein response, at least in part via dephosphorylation of Ire1p; dosage-dependent positive regulator of the G1/S phase transition through control of the timing of START" Verified chr12:847387-849123 847387-849123 99.2% 60.96 79.54 64.45 49.35 89.99 83.61 70.25 56.90 86.80 0.26 0.23 0.36 0.61 0.56 Matched[4106]
YLR361C-A Putative protein of unknown function Uncharacterized chr12:849382-849678 849382-849678 99.3% 135.63 179.71 186.49 213.62 325.52 193.27 157.67 200.06 259.40 0.58 0.81 1.07 0.37 NaN Matched[4107]
YLR362W STE11 "Signal transducing MEK kinase involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p" Verified chr12:849865-852018 849865-852018 98.7% 64.43 63.49 68.67 54.09 79.01 60.67 63.96 61.38 69.84 0.24 0.25 0.29 0.19 0.69 Matched[4108]
YLR363C NMD4 "Protein interacting with Nam7p, may be involved in the nonsense-mediated mRNA decay pathway" Verified chr12:852494-853150 852494-853150 99.5% 139.21 154.51 162.16 162.16 195.82 183.58 146.86 162.16 189.70 0.54 0.66 0.79 0.23 0.39 Matched[4109]
YLR363W-A Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus Uncharacterized chr12:853460-853717 853460-853717 98.3% 264.26 145.93 165.65 157.76 39.44 3.94 205.09 161.71 21.69 0.76 0.66 0.09 -2.90 -2.26 Matched[4110]
YLR364W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLR364W is not an essential gene Uncharacterized chr12:854061-854390 854061-854390 98.6% 70.71 98.37 73.78 52.26 52.26 64.56 84.54 63.02 58.41 0.31 0.26 0.24 -0.11 -0.29 Matched[4111]
YLR365W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps dubious gene YLR364C-A; YLR365W is not an essential gene" Dubious chr12:855198-855530 855198-855530 99.3% 3.03 3.03 0.00 0.00 0.00 0.00 3.03 0.00 0.00 0.01 0.00 0.00 NaN 0.16
YLR366W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR364C-A" Dubious chr12:855537-855842 855537-855842 99.1% 23.09 29.69 26.39 16.49 26.39 13.20 26.39 21.44 19.79 0.10 0.09 0.08 -0.12 NaN Overlap[4112]
YLR364C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR366W" Dubious chr12:855522-855644 855522-855644 98.7% 0.00 0.00 0.00 0.00 0.00 8.24 0.00 0.00 4.12 0.00 0.00 0.02 Inf NaN
YLR367W RPS22B Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Ap and has similarity to E. coli S8 and rat S15a ribosomal proteins Verified chr12:855876-857316 855876-855877,856434-856573,857057-857316 84.1% 2381.36 1842.97 2203.87 1502.77 1227.66 704.06 2112.17 1853.32 965.86 7.80 7.52 4.00 -0.94 -1.63 Matched[4112]
YLR368W MDM30 "F-box protein; physically associates with mitochondria and is required for normal mitochondrial fusion in rich medium, during sporulation, and in mating cells; promotes ubiquitin-mediated degradation of Gal4p in some strains" Verified chr12:857539-859335 857539-859335 98.8% 80.53 79.40 68.70 59.13 98.55 62.51 79.97 63.92 80.53 0.30 0.26 0.33 0.33 0.40 Covered/w/another[4113]
YLR369W SSQ1 "Mitochondrial hsp70-type molecular chaperone, required for assembly of iron/sulfur clusters into proteins at a step after cluster synthesis, and for maturation of Yfh1p, which is a homolog of human frataxin implicated in Friedreich's ataxia" Verified chr12:859551-861524 859551-861524 98.7% 66.75 70.86 68.81 64.18 126.83 96.53 68.81 66.50 111.68 0.25 0.27 0.46 0.75 0.86 Covered/w/another[4113]
YLR370C ARC18 "Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches" Verified chr12:861717-862253 861717-862253 98.6% 596.74 668.50 628.85 649.62 1229.36 787.47 632.62 639.23 1008.42 2.34 2.59 4.18 0.66 0.64 Matched[4114]
YLR371W ROM2 "GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically lethal with mutations in rom1, which also encodes a GEP" Verified chr12:862713-866783 862713-866783 98.8% 117.87 116.63 93.25 92.26 138.76 127.32 117.25 92.75 133.04 0.43 0.38 0.55 0.52 0.66 Matched[4115]
YLR372W SUR4 "Elongase, involved in fatty acid and sphingolipid biosynthesis; synthesizes very long chain 20-26-carbon fatty acids from C18-CoA primers; involved in regulation of sphingolipid biosynthesis" Verified chr12:867353-868390 867353-868390 99.1% 1642.17 1334.14 1416.74 1345.80 282.76 194.34 1488.16 1381.27 238.55 5.49 5.61 0.99 -2.53 -2.17 Matched[4116]
YLR373C VID22 "Glycosylated integral membrane protein localized to the plasma membrane; plays a role in fructose-1,6-bisphosphatase (FBPase) degradation; involved in FBPase transport from the cytosol to Vid (vacuole import and degradation) vesicles" Verified chr12:868661-871366 868661-871366 99.0% 106.79 101.19 92.98 82.90 85.88 77.29 103.99 87.94 81.59 0.38 0.36 0.34 -0.11 0.03 Matched[4117]
YLR375W STP3 "Zinc-finger protein of unknown function, possibly involved in pre-tRNA splicing and in uptake of branched-chain amino acids" Verified chr12:871696-872727 871696-872727 98.7% 395.70 421.22 302.42 241.54 306.35 197.36 408.46 271.98 251.85 1.51 1.10 1.04 -0.11 0.24 Matched[4118]
YLR374C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF STP3/YLR375W" Dubious chr12:871452-871841 871452-871841 98.4% 99.07 122.53 78.21 80.82 54.75 62.57 110.80 79.51 58.66 0.41 0.32 0.24 -0.44 1.13 Covered/w/another[4118]
YLR376C PSY3 Protein of unknown function; deletion results in a mutator phenotype suggesting a role for this protein as a mutational suppressor; deletion increases sensitivity to anticancer drugs oxaliplatin and cisplatin but not mitomycin C Verified chr12:872825-873553 872825-873553 99.3% 87.05 88.43 82.90 80.14 114.68 64.94 87.74 81.52 89.81 0.32 0.33 0.37 0.14 -0.07 Matched[4119]
YLR377C FBP1 "Fructose-1,6-bisphosphatase, key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism" Verified chr12:873745-874791 873745-874791 98.8% 17.40 19.33 17.40 14.50 34.80 25.13 18.37 15.95 29.96 0.07 0.06 0.12 0.91 -0.17 Frag>80[4120]
YLR379W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the essential ORF SEC61/YLR378C" Dubious chr12:876921-877295 876921-877295 98.3% 811.31 746.18 852.01 770.60 466.70 662.07 778.75 811.31 564.39 2.87 3.29 2.34 -0.52 0.04 Covered/w/another[4122]
YLR378C SEC61 "Essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms a channel for SRP-dependent protein import and retrograde transport of misfolded proteins out of the ER; with Sec63 complex allows SRP-independent protein import into ER" Verified chr12:875735-877177 875735-877177 98.3% 1252.99 1087.39 1221.28 1047.92 817.48 856.94 1170.19 1134.60 837.21 4.32 4.61 3.47 -0.44 -0.16 Frag>80[4121,4122]
YLR380W CSR1 Phosphatidylinositol transfer protein with a potential role in lipid turnover; interacts specifically with thioredoxin peroxidase (Tsa2p) and may have a role in oxidative stress resistance Verified chr12:878282-879508 878282-879508 98.7% 274.90 307.93 254.27 234.45 222.89 251.79 291.41 244.36 237.34 1.08 0.99 0.98 -0.04 0.63 Matched[4123]
YLR381W CTF3 Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p; may bind the kinetochore to spindle microtubules Verified chr12:879723-881924 879723-881924 99.1% 57.73 60.94 40.32 45.82 48.11 36.20 59.33 43.07 42.15 0.22 0.17 0.17 -0.03 -0.06 Matched[4124]
YLR382C NAM2 "Mitochondrial leucyl-tRNA synthetase, also has a direct role in splicing of several mitochondrial group I introns; indirectly required for mitochondrial genome maintenance" Verified chr12:882067-884751 882067-884751 99.1% 105.97 119.12 109.35 93.57 99.96 104.84 112.54 101.46 102.40 0.42 0.41 0.42 0.01 0.52 Matched[4125]
YLR383W SMC6 "Protein involved in structural maintenance of chromosomes; essential subunit of Mms21-Smc5-Smc6 complex; required for growth, DNA repair, interchromosomal and sister chromatid recombination; homologous to S. pombe rad18" Verified chr12:885288-888632 885288-888632 98.4% 104.77 89.89 93.23 78.04 43.73 36.74 97.33 85.63 40.24 0.36 0.35 0.17 -1.09 -0.61 Matched[4126]
YLR384C IKI3 "Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; maintains structural integrity of Elongator; homolog of human IKAP, mutations in which cause familial dysautonomia (FD)" Verified chr12:888851-892900 888851-892900 99.2% 219.06 154.34 169.02 138.41 38.09 27.38 186.70 153.72 32.73 0.69 0.62 0.14 -2.23 -1.47 Frag>80[4127,4128]
YLR385C SWC7 "Protein of unknown function, component of the Swr1p complex that incorporates Htz1p into chromatin" Verified chr12:892992-893390 892992-893390 99.1% 15.17 12.64 15.17 10.11 2.53 0.00 13.91 12.64 1.26 0.05 0.05 0.01 -3.32 -0.79
YLR386W VAC14 "Protein involved in regulated synthesis of PtdIns(3,5)P(2), in control of trafficking of some proteins to the vacuole lumen via the MVB, and in maintenance of vacuole size and acidity; interacts with Fig4p; activator of Fab1p" Verified chr12:893628-896270 893628-896270 98.9% 103.30 87.99 85.32 85.32 86.08 73.84 95.64 85.32 79.96 0.35 0.35 0.33 -0.09 0.28 Matched[4129]
YLR387C REH1 "Protein of unknown function, similar to Rei1p but not involved in bud growth; contains dispersed C2H2 zinc finger domains" Verified chr12:896374-897672 896374-897672 99.2% 176.13 155.96 185.45 178.46 277.78 164.50 166.05 181.95 221.14 0.61 0.74 0.92 0.28 0.45 Matched[4130]
YLR388W RPS29A Protein component of the small (40S) ribosomal subunit; nearly identical to Rps29Bp and has similarity to rat S29 and E. coli S14 ribosomal proteins Verified chr12:898157-898821 898157-898158,898646-898821 82.0% 5123.29 4034.25 4671.23 3643.84 1383.56 938.36 4578.77 4157.53 1160.96 16.90 16.88 4.81 -1.84 -3.08 Matched[4131]
YLR389C STE23 "Metalloprotease involved, with homolog Axl1p, in N-terminal processing of pro-a-factor to the mature form; member of the insulin-degrading enzyme family" Verified chr12:899577-902660 899577-902660 99.0% 181.50 185.10 141.53 151.36 82.23 66.83 183.30 146.45 74.53 0.68 0.59 0.31 -0.97 -0.39 Frag>80[4132,4133]
YLR390W ECM19 "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr12:903066-903404 903066-903404 98.8% 203.01 220.92 220.92 194.05 232.86 101.51 211.97 207.49 167.18 0.78 0.84 0.69 -0.31 0.06 Matched[4134]
YLR390W-A CCW14 "Covalently linked cell wall glycoprotein, present in the inner layer of the cell wall" Verified chr12:903724-904440 903724-904440 95.4% 2749.66 3011.33 2711.66 2505.54 2618.10 2096.24 2880.50 2608.60 2357.17 10.63 10.59 9.77 -0.15 0.14 Matched[4135]
YLR392C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLR392C is not an essential gene Uncharacterized chr12:904749-906305 904749-906305 99.3% 65.31 67.90 74.37 74.37 166.20 93.77 66.61 74.37 129.98 0.25 0.30 0.54 0.81 1.04 Matched[4136]
YLR393W ATP10 "Mitochondrial inner membrane protein required for assembly of the F0 sector of mitochondrial F1F0 ATP synthase, interacts genetically with ATP6" Verified chr12:907079-907918 907079-907918 98.5% 58.01 61.63 60.43 47.13 68.89 79.76 59.82 53.78 74.32 0.22 0.22 0.31 0.47 1.00 Covered/w/another[4137]
YLR394W CST9 SUMO E3 ligase; required for synaptonemal complex formation; localizes to synapsis initiation sites on meiotic chromosomes; potential Cdc28p substrate Verified chr12:907950-909398 907950-909398 99.1% 110.78 105.90 98.24 116.35 128.19 132.37 108.34 107.29 130.28 0.40 0.44 0.54 0.28 0.53 Covered/w/another[4137]
YLR395C COX8 "Subunit VIII of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain" Verified chr12:909729-909965 909729-909965 98.7% 658.35 842.18 795.15 923.41 1320.98 803.71 750.27 859.28 1062.34 2.77 3.49 4.40 0.31 0.01 Matched[4138]
YLR396C VPS33 ATP-binding protein that is a subunit of the HOPS complex and the CORVET tethering complex; essential for membrane docking and fusion at both the Golgi-to-endosome and endosome-to-vacuole stages of protein transport Verified chr12:910235-912310 910235-912310 99.2% 74.78 75.75 55.36 55.36 81.58 55.84 75.26 55.36 68.71 0.28 0.22 0.28 0.31 0.56 Matched[4139]
YLR397C AFG2 "ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex; may be involved in degradation of aberrant mRNAs" Verified chr12:912550-914892 912550-914892 98.9% 128.55 82.39 73.76 57.80 28.47 18.55 105.47 65.78 23.51 0.39 0.27 0.10 -1.48 -1.16 Matched[4140]
YLR398C SKI2 "Putative RNA helicase, involved in exosome mediated 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs; forms complex with Ski3p and Ski8p; required for repressing propagation of dsRNA viruses" Verified chr12:915156-919019 915156-919019 99.3% 125.64 117.56 110.78 104.26 76.37 100.09 121.60 107.52 88.23 0.45 0.44 0.37 -0.29 0.29 Matched[4141]
YLR399W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the characterized ORF BDF1/YLR399C" Dubious chr12:920869-920973 920869-920973 99.4% 373.65 297.01 229.94 364.07 364.07 565.27 335.33 297.01 464.67 1.24 1.21 1.93 0.65 NaN Covered/w/another[4143]
YLR399C BDF1 Protein involved in transcription initiation at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf2p Verified chr12:919536-921596 919536-921596 99.1% 426.40 434.24 431.79 364.23 731.89 621.25 430.32 398.01 676.57 1.59 1.62 2.80 0.77 0.85 Matched[4143]
YLR400W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr12:922063-922536 922063-922536 99.4% 59.41 50.92 46.68 23.34 6.36 6.36 55.16 35.01 6.36 0.20 0.14 0.03 -2.46 0.59 Overlap[4144]
YLR401C DUS3 "Dihydrouridine synthase, member of a widespread family of conserved proteins including Smm1p, Dus1p, and Dus4p; contains a consensus oleate response element (ORE) in its promoter region" Verified chr12:922442-924448 922442-924448 99.1% 166.46 129.75 118.68 103.60 14.58 4.53 148.10 111.14 9.56 0.55 0.45 0.04 -3.54 -3.39 Matched[4144]
YLR402W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr12:924564-925079 924564-925079 98.9% 31.35 15.68 19.60 15.68 11.76 21.56 23.52 17.64 16.66 0.09 0.07 0.07 -0.08 -0.30 Overlap[4145]
YLR403W SFP1 "Transcription factor that controls expression of many ribosome biogenesis genes in response to nutrients and stress, regulates G2/M transitions during mitotic cell cycle and DNA-damage response, involved in cell size modulation" Verified chr12:925567-927618 925567-927618 98.8% 174.09 165.71 145.98 114.91 130.69 124.28 169.90 130.45 127.49 0.63 0.53 0.53 -0.03 0.89 Matched[4145]
YLR404W Putative protein of unknown function; may be an integral membrane protein; YLR404W is not an essential gene Uncharacterized chr12:928742-929599 928742-929599 99.0% 98.86 94.15 80.03 81.21 82.39 44.72 96.51 80.62 63.55 0.36 0.33 0.26 -0.34 -0.33 Matched[4147]
YLR405W DUS4 "Dihydrouridine synthase, member of a widespread family of conserved proteins including Smm1p, Dus1p, and Dus3p" Verified chr12:929788-930891 929788-930891 98.6% 160.80 124.97 91.89 91.89 38.59 17.46 142.88 91.89 28.03 0.53 0.37 0.12 -1.71 -1.84 Matched[4148]
YLR406C RPL31B "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Ap and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p" Verified chr12:931064-931754 931064-931348,931698-931754 81.7% 4397.49 3595.34 3455.69 2746.64 637.42 386.75 3996.42 3101.16 512.09 14.75 12.59 2.12 -2.60 -3.45 Frag>80[4149,4150]
YLR406C-A Putative protein of unknown function Uncharacterized chr12:932205-932354 932205-932354 98.1% 0.00 6.80 6.80 6.80 0.00 0.00 3.40 6.80 0.00 0.01 0.03 0.00 -Inf NaN
YLR407W Putative protein of unknown function; YLR407W is not an essential gene Uncharacterized chr12:932966-933655 932966-933655 98.2% 159.31 163.74 109.16 94.41 54.58 36.88 161.52 101.78 45.73 0.60 0.41 0.19 -1.15 -0.31 Matched[4151]
YLR408C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endosome; YLR408C is not an essential gene Uncharacterized chr12:933883-934251 933883-934251 99.3% 84.60 114.62 120.08 120.08 324.77 131.00 99.61 120.08 227.88 0.37 0.49 0.94 0.92 0.48 Matched[4152]
YLR409C UTP21 "Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data" Verified chr12:934412-937231 934412-937231 99.1% 167.44 117.35 108.41 72.27 12.52 3.22 142.40 90.34 7.87 0.53 0.37 0.03 -3.52 -4.17 Matched[4153]
YLR410W VIP1 "Inositol hexakisphosphate (IP6) and inositol heptakisphosphate (IP7) kinase; generation of IP7 by Vip1p is important for phosphate signaling; likely involved in cortical actin cytoskeleton function, by analogy with S. pombe ortholog asp1" Verified chr12:937539-940979 937539-940979 98.7% 243.47 241.70 222.57 205.20 134.54 156.03 242.58 213.88 145.29 0.90 0.87 0.60 -0.56 0.04 Matched[4154]
YLR411W CTR3 "High-affinity copper transporter of the plasma membrane, acts as a trimer; gene is disrupted by a Ty2 transposon insertion in many laboratory strains of S. cerevisiae" Verified chr12:947251-947976 947251-947976 98.7% 30.70 32.09 39.07 26.51 32.09 30.70 31.40 32.79 31.40 0.12 0.13 0.13 -0.06 0.04 Matched[4155]
YLR412W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; YLR412W is not an essential gene Uncharacterized chr12:948366-949190 948366-949190 98.9% 264.64 267.09 254.84 219.31 147.02 134.77 265.86 237.07 140.90 0.98 0.96 0.58 -0.75 -0.21 Matched[4156]
YLR412C-A Putative protein of unknown function Uncharacterized chr12:950264-950470 950264-950470 99.2% 29.22 19.48 9.74 4.87 14.61 48.70 24.35 7.31 31.66 0.09 0.03 0.13 2.12 NaN Covered[4157]
YLR413W Putative protein of unknown function; YLR413W is not an essential gene Uncharacterized chr12:951153-953180 951153-953180 99.2% 577.69 1715.17 654.25 552.34 56.68 21.87 1146.43 603.29 39.27 4.23 2.45 0.16 -3.94 -2.20 Matched[4158]
YLR414C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the bud and cytoplasm; Hog1p is required for transcriptional induction in response to cell wall damage; YLR414C is not an essential gene Uncharacterized chr12:953350-954141 953350-954141 98.7% 230.19 260.88 249.37 232.75 645.81 387.49 245.54 241.06 516.65 0.91 0.98 2.14 1.10 0.50 Matched[4159]
YLR415C Putative protein of unknown function; YLR415C is not an essential gene Uncharacterized chr12:954256-954594 954256-954594 97.8% 6.03 9.05 18.09 3.02 21.11 6.03 7.54 10.55 13.57 0.03 0.04 0.06 0.36 0.25 Matched[4160]
YLR416C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr12:954488-954886 954488-954886 98.0% 7.67 5.12 2.56 5.12 10.23 2.56 6.39 3.84 6.39 0.02 0.02 0.03 0.74 0.49 Matched[4160]
YLR417W VPS36 Component of the ESCRT-II complex; contains the GLUE (GRAM Like Ubiquitin binding in EAP45) domain which is involved in interactions with ESCRT-I and ubiquitin-dependent sorting of proteins into the endosome Verified chr12:955007-956707 955007-956707 98.7% 72.06 85.16 82.18 66.10 105.41 60.74 78.61 74.14 83.08 0.29 0.30 0.34 0.16 0.20 Matched[4161]
YLR418C CDC73 "Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p, distinct from Srb-containing Pol II complexes; required for expression of certain genes, modification of some histones, and telomere maintenance" Verified chr12:956911-958092 956911-958092 99.2% 175.75 144.18 180.01 155.27 166.36 106.64 159.97 167.64 136.50 0.59 0.68 0.57 -0.30 0.11 Matched[4162]
YLR419W "Putative helicase with limited sequence similarity to human Rb protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YLR419W is not an essential gene" Uncharacterized chr12:958425-962732 958425-962732 98.8% 63.90 44.17 44.40 45.81 10.57 11.04 54.04 45.11 10.81 0.20 0.18 0.04 -2.06 -1.00 Matched[4163]
YLR420W URA4 "Dihydroorotase, catalyzes the third enzymatic step in the de novo biosynthesis of pyrimidines, converting carbamoyl-L-aspartate into dihydroorotate" Verified chr12:963782-964876 963782-964876 98.7% 883.24 540.12 746.36 776.88 328.32 320.92 711.68 761.62 324.62 2.63 3.09 1.35 -1.23 -0.64 Matched[4165]
YLR421C RPN13 Subunit of the 19S regulatory particle of the 26S proteasome lid Verified chr12:965087-965557 965087-965557 99.4% 709.46 591.93 628.26 540.65 1096.25 638.95 650.70 584.45 867.60 2.40 2.37 3.59 0.57 -0.13 Matched[4166]
YLR422W "Protein of unknown function with similarity to human DOCK proteins (guanine nucleotide exchange factors); interacts with Ino4p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm, YLR422W is not an essential protein" Uncharacterized chr12:965894-971692 965894-971692 98.9% 55.61 61.37 55.96 42.71 60.67 73.75 58.49 49.34 67.21 0.22 0.20 0.28 0.45 0.92 Frag>80[4167,4168]
YLR423C ATG17 Scaffold potein responsible for pre-autophagosomal structure organization; interacts with and is required for activation of Apg1p protein kinase; involved in autophagy but not in the Cvt (cytoplasm to vacuole targeting) pathway Verified chr12:971914-973167 971914-973167 99.6% 61.68 87.31 66.48 76.10 140.18 83.31 74.49 71.29 111.74 0.27 0.29 0.46 0.65 0.47 Matched[4169]
YLR424W SPP382 "Essential protein that forms a dimer with Ntr2p; also forms a trimer, with Ntr2p and Prp43p, that is involved in spliceosome disassembly; found also in a multisubunit complex with the splicing factor Clf1p; suppressor of prp38-1 mutation" Verified chr12:973392-975518 973392-975518 98.7% 43.84 43.36 38.60 34.79 53.85 38.12 43.60 36.69 45.98 0.16 0.15 0.19 0.33 0.45 Matched[4170]
YLR425W TUS1 Guanine nucleotide exchange factor (GEF) that functions to modulate Rho1p activity as part of the cell integrity signaling pathway; multicopy suppressor of tor2 mutation and ypk1 ypk2 double mutation; potential Cdc28p substrate Verified chr12:982891-986814 982891-986814 98.8% 52.86 64.72 46.41 44.35 64.20 63.69 58.79 45.38 63.94 0.22 0.18 0.26 0.49 0.88 Matched[4172]
YLR426W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; proposed to be involved in resistance to mechlorethamine and streptozotocin" Uncharacterized chr12:987059-988110 987059-987138,987210-988110 98.7% 140.53 139.49 111.59 76.46 136.39 76.46 140.01 94.03 106.43 0.52 0.38 0.44 0.18 0.41 Matched[4173]
YLR427W MAG2 Cytoplasmic protein of unknown function predicted to encode a DNA-3-methyladenine glycosidase II that catalyzes the hydrolysis of alkylated DNA Verified chr12:988425-990437 988425-990437 98.6% 181.81 180.30 165.19 143.53 117.34 118.35 181.05 154.36 117.85 0.67 0.63 0.49 -0.39 0.08 Matched[4174]
YLR429W CRN1 "Coronin, cortical actin cytoskeletal component that associates with the Arp2p/Arp3p complex to regulate its activity" Verified chr12:990774-992729 990774-992729 98.5% 519.42 493.99 509.04 538.10 377.76 363.75 506.70 523.57 370.75 1.87 2.13 1.54 -0.50 -0.13 Matched[4175]
YLR428C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF CRN1" Dubious chr12:990614-990958 990614-990958 98.3% 165.17 188.77 200.57 182.87 132.73 106.18 176.97 191.72 119.45 0.65 0.78 0.49 -0.68 -0.00 Overlap[4174,4175]
YLR430W SEN1 Presumed helicase required for RNA polymerase II transcription termination and processing of RNAs; homolog of Senataxin which causes Ataxia-Oculomotor Apraxia 2 and a dominant form of amyotrophic lateral sclerosis Verified chr12:993431-1000126 993431-1000126 98.8% 138.07 106.61 102.38 77.73 33.57 37.96 122.34 90.05 35.76 0.45 0.37 0.15 -1.33 -0.69 Frag<80[4176]
YLR431C ATG23 "Peripheral membrane protein, required for autophagy and for the cytoplasm-to-vacuole targeting (Cvt) pathway" Verified chr12:1000339-1001700 1000339-1001700 99.3% 61.39 74.70 74.70 64.35 83.58 63.61 68.05 69.52 73.59 0.25 0.28 0.30 0.08 0.34 Covered[4177]
YLR432W IMD3 "Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, member of a four-gene family in S. cerevisiae, constitutively expressed" Verified chr12:1002554-1004125 1002554-1004125 55.5% 1737.70 1232.21 1486.67 1182.92 240.71 179.96 1484.96 1334.80 210.34 5.48 5.42 0.87 -2.67 -2.24 Frag>80[4178,4179]
YLR433C CNA1 "Calcineurin A; one isoform (the other is CMP2) of the catalytic subunit of calcineurin, a Ca++/calmodulin-regulated protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is CNB1" Verified chr12:1004344-1006005 1004344-1006005 99.1% 168.81 156.67 158.49 137.84 69.83 74.69 162.74 148.17 72.26 0.60 0.60 0.30 -1.04 -0.66 Matched[4180]
YLR435W TSR2 Protein with a potential role in pre-rRNA processing Verified chr12:1006375-1006992 1006375-1006992 98.3% 266.59 133.30 169.50 164.56 19.75 4.94 199.95 167.03 12.34 0.74 0.68 0.05 -3.76 -3.57 Matched[4181]
YLR434C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF TSR2/YLR435W" Dubious chr12:1006022-1006405 1006022-1006405 99.0% 63.14 26.31 60.51 49.98 13.15 18.41 44.72 55.24 15.78 0.17 0.22 0.07 -1.81 -3.03 Overlap[4180,4181]
YLR436C ECM30 Non-essential protein of unknown function Verified chr12:1007418-1011242 1007418-1011242 98.8% 159.75 181.18 145.21 143.36 166.90 206.04 170.47 144.28 186.47 0.63 0.59 0.77 0.37 1.03 Matched[4182]
YLR437C Putative protein of unknown function; epitope tagged protein localizes to the cytoplasm Uncharacterized chr12:1011619-1012020 1011619-1012020 95.5% 229.19 270.86 276.07 200.54 463.59 273.47 250.03 238.31 368.53 0.92 0.97 1.53 0.63 0.63 Frag>80[4183,4184]
YLR438W CAR2 "L-ornithine transaminase (OTAse), catalyzes the second step of arginine degradation, expression is dually-regulated by allophanate induction and a specific arginine induction process; not nitrogen catabolite repression sensitive" Verified chr12:1012498-1013772 1012498-1013772 98.6% 367.51 544.10 509.10 437.51 1672.07 1558.32 455.80 473.30 1615.19 1.68 1.92 6.69 1.77 1.86 Matched[4185]
YLR437C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF CAR2/YLR438W" Dubious chr12:1012456-1012683 1012456-1012683 98.7% 217.78 355.56 302.22 297.78 1062.22 1195.56 286.67 300.00 1128.89 1.06 1.22 4.68 1.91 NaN Covered/w/another[4185]
YLR438C-A LSM3 "Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA" Verified chr12:1013906-1014175 1013906-1014175 98.9% 625.27 527.93 640.25 531.67 572.85 340.72 576.60 585.96 456.79 2.13 2.38 1.89 -0.36 -0.27 Matched[4186]
YLR439W MRPL4 Mitochondrial ribosomal protein of the large subunit Verified chr12:1014488-1015447 1014488-1015447 98.7% 188.90 179.40 186.79 176.24 224.78 181.51 184.15 181.51 203.15 0.68 0.74 0.84 0.16 0.47 Matched[4187]
YLR440C SEC39 Protein of unknown function proposed to be involved in protein secretion Verified chr12:1015565-1017694 1015565-1017694 99.3% 112.01 106.34 98.78 73.73 67.58 59.55 109.17 86.25 63.57 0.40 0.35 0.26 -0.44 -0.02 Matched[4188]
YLR441C RPS1A Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Bp and has similarity to rat S3a ribosomal protein Verified chr12:1018138-1018905 1018138-1018905 74.5% 10407.98 7602.94 8773.16 7919.07 2048.76 1316.93 9005.46 8346.12 1682.85 33.24 33.88 6.97 -2.31 -2.19 Matched[4189]
YLR442C SIR3 "Silencing protein that interacts with Sir2p and Sir4p, and histone H3 and H4 tails, to establish a transcriptionally silent chromatin state; required for spreading of silenced chromatin; recruited to chromatin through interaction with Rap1p" Verified chr12:1019312-1022248 1019312-1022248 99.4% 76.08 77.11 70.25 68.20 53.80 59.63 76.59 69.23 56.72 0.28 0.28 0.23 -0.29 0.34 Matched[4190]
YLR443W ECM7 Non-essential protein of unknown function Verified chr12:1022622-1023968 1022622-1023968 98.7% 124.10 110.56 97.02 81.98 105.30 69.19 117.33 89.50 87.25 0.43 0.36 0.36 -0.04 -0.26 Matched[4191]
YLR444C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr12:1023683-1023985 1023683-1023985 98.6% 140.59 150.63 117.15 137.24 107.11 56.90 145.61 127.20 82.01 0.54 0.52 0.34 -0.63 0.04 Covered/w/another[4191]
YLR445W Hypothetical protein Uncharacterized chr12:1024186-1024834 1024186-1024569,1024652-1024834 98.5% 5.37 8.95 1.79 3.58 8.95 14.32 7.16 2.69 11.64 0.03 0.01 0.05 2.12 -0.40 Frag<80[4192]
YLR446W Putative protein of unknown function with similarity to hexokinases; transcript is upregulated during sporulation and the unfolded protein response; YLR446W is not an essential gene Uncharacterized chr12:1025211-1026512 1025211-1026512 99.1% 69.01 67.46 48.85 39.54 107.00 96.15 68.23 44.20 101.57 0.25 0.18 0.42 1.20 1.04 Matched[4193]
YLR447C VMA6 "Subunit d of the five-subunit V0 integral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found in the endomembrane system; stabilizes VO subunits; required for V1 domain assembly on the vacuolar membrane" Verified chr12:1026853-1027890 1026853-1027890 99.3% 1914.99 2190.64 1746.11 1734.46 1127.84 780.36 2052.82 1740.28 954.10 7.58 7.06 3.95 -0.87 -0.96 Frag>80[4194,4195]
YLR448W RPL6B "Protein component of the large (60S) ribosomal subunit, has similarity to Rpl6Ap and to rat L6 ribosomal protein; binds to 5.8S rRNA" Verified chr12:1028850-1029764 1028850-1028864,1029249-1029764 82.6% 4126.85 3301.94 3429.55 2600.08 742.88 366.88 3714.39 3014.81 554.88 13.71 12.24 2.30 -2.44 -2.40 Frag>80[4196,4197]
YLR449W FPR4 "Peptidyl-prolyl cis-trans isomerase (PPIase) (proline isomerase) localized to the nucleus; catalyzes isomerization of proline residues in histones H3 and H4, which affects lysine methylation of those histones" Verified chr12:1030830-1032008 1030830-1032008 97.6% 713.27 391.82 607.28 523.00 90.35 59.95 552.54 565.14 75.15 2.04 2.29 0.31 -2.91 -1.24 Matched[4198]
YLR450W HMG2 "One of two isozymes of HMG-CoA reductase that convert HMG-CoA to mevalonate, a rate-limiting step in sterol biosynthesis; overproduction induces assembly of peripheral ER membrane arrays and short nuclear-associated membrane stacks" Verified chr12:1032624-1035761 1032624-1035761 98.7% 151.49 281.02 149.55 162.80 92.06 123.39 216.25 156.17 107.72 0.80 0.63 0.45 -0.54 0.15 Matched[4199]
YLR451W LEU3 "Zinc-finger transcription factor that regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation; positively regulated by alpha-isopropylmalate, an intermediate in leucine biosynthesis" Verified chr12:1036090-1038750 1036090-1038750 98.7% 94.78 88.69 64.33 48.34 39.21 31.59 91.73 56.33 35.40 0.34 0.23 0.15 -0.67 -0.50 Matched[4200]
YLR452C SST2 "GTPase-activating protein for Gpa1p, regulates desensitization to alpha factor pheromone; also required to prevent receptor-independent signaling of the mating pathway; member of the RGS (regulator of G-protein signaling) family" Verified chr12:1039268-1041364 1039268-1041364 99.1% 399.06 439.02 369.70 309.04 139.12 91.46 419.04 339.37 115.29 1.55 1.38 0.48 -1.56 -1.02 Matched[4201]
YLR453C RIF2 Protein that binds to the Rap1p C-terminus and acts synergistically with Rif1p to help control telomere length and establish telomeric silencing; deletion results in telomere elongation Verified chr12:1041797-1042984 1041797-1042984 99.2% 37.33 39.88 29.70 30.55 30.55 26.30 38.61 30.12 28.42 0.14 0.12 0.12 -0.08 0.51 Matched[4202]
YLR454W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr12:1043996-1051882 1043996-1051882 99.0% 94.17 110.18 89.68 89.43 110.31 155.92 102.17 89.55 133.11 0.38 0.36 0.55 0.57 0.71 Frag>80[4203,4204]
YLR455W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) Uncharacterized chr12:1053627-1054541 1053627-1054541 98.6% 283.62 248.17 254.81 218.25 570.56 415.45 265.89 236.53 493.01 0.98 0.96 2.04 1.06 1.14 Covered[4205]
YLR456W Putative protein of unknown function Uncharacterized chr12:1055068-1055682 1055068-1055682 99.2% 85.25 80.33 80.33 77.05 80.33 49.18 82.79 78.69 64.76 0.31 0.32 0.27 -0.28 -0.64 Covered/w/another[4206]
YLR458W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps 5' end of essential NBP1 gene required for mitosis" Dubious chr12:1056453-1056833 1056453-1056833 99.6% 21.09 65.91 34.27 31.64 52.73 47.46 43.50 32.96 50.09 0.16 0.13 0.21 0.60 0.01 Covered/w/another[4206]
YLR457C NBP1 "Spindle pole body (SPB) component, required for the insertion of the duplication plaque into the nuclear membrane during SPB duplication; essential for bipolar spindle formation; component of the Mps2p-Bbp1p complex" Verified chr12:1055810-1056769 1055810-1056769 99.3% 61.89 82.87 61.89 44.06 75.52 58.74 72.38 52.97 67.13 0.27 0.22 0.28 0.34 0.54 Matched[4206]
YLR459W GAB1 "GPI transamidase subunit, involved in attachment of glycosylphosphatidylinositol (GPI) anchors to proteins; may have a role in recognition of the attachment signal or of the lipid portion of GPI" Verified chr12:1057332-1058516 1057332-1058516 99.3% 266.08 272.03 221.88 201.47 192.12 150.47 269.06 211.67 171.29 0.99 0.86 0.71 -0.31 -0.20 Matched[4207]
YLR460C "Putative protein of unknown function, possibly up-regulated by iodine" Uncharacterized chr12:1059755-1060885 1059755-1060885 44.3% 41.92 37.92 47.90 31.94 35.93 35.93 39.92 39.92 35.93 0.15 0.16 0.15 -0.15 -0.23 Frag<80[4209]
YLR461W PAU4 "Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme" Verified chr12:1062917-1063279 1062917-1063279 8.4% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.57
YLR462W Putative protein of unknown function with similarity to helicases; YLR462W is within the telomere on the right arm of chromosome XII Uncharacterized chr12:1065954-1066562 1065954-1066562 0.9% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN -0.23
YLR464W Putative protein of unknown function with similarity to helicases; YLR464W contains an intron and overlaps the verified gene YRF1-4/YLR466W and two dubious ORFs YLR463C and YLR465C Uncharacterized chr12:1066570-1067499 1066570-1067082,1067362-1067499 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.40
YLR463C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the uncharacterized ORFs YLR462W and YLR464W" Dubious chr12:1066263-1066814 1066263-1066814 0.5% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN -0.33
YLR466W YRF1-4 "Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p" Verified chr12:1067085-1071233 1067085-1071233 0.1% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.30
YLR465C BSC3 "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 100% of YLR465C overlaps the uncharacterized ORF YLR464W and 86% of YLR465C overlaps the verified gene YRF1-4" Dubious chr12:1067043-1067351 1067043-1067351 1.4% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN -0.33
YLR466C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YRF1-4/YLR466W" Dubious chr12:1070385-1070867 1070385-1070867 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YLR466C-B "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Uncharacterized chr12:1071592-1071708 1071592-1071708 15.0% 171.43 114.29 228.57 57.14 171.43 285.71 142.86 142.86 228.57 0.53 0.58 0.95 0.68 NaN Matched[4210]
YLR467W YRF1-5 "Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p" Verified chr12:1072506-1077896 1072506-1077896 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.30
YLR467C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YRF1-4/YLR466W" Dubious chr12:1077048-1077530 1077048-1077530 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YML133W-B "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the uncharacterized ORF YML133C" Dubious chr13:827-1309 827-1309 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YML133W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the uncharacterized ORF YML133C" Dubious chr13:1610-2185 1610-2185 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YML133C "Putative protein of unknown function with similarity to helicases; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YML133C contains an intron" Uncharacterized chr13:461-4684 461-3791,3891-4684 0.1% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.30
YML132W COS3 "Protein involved in salt resistance; interacts with sodium:hydrogen antiporter Nha1p; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" Verified chr13:7244-8383 7244-8383 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.13
YML131W Putative protein of unknown function with similarity to oxidoreductases; HOG1 and SKO1-dependent mRNA expression is induced after osmotic shock; GFP-fusion protein localizes to the cytoplasm and is induced by the DNA-damaging agent MMS Uncharacterized chr13:10199-11296 10199-11296 98.8% 183.51 91.29 239.76 193.65 489.66 367.02 137.40 216.71 428.34 0.51 0.88 1.77 0.98 1.19 Matched[4213]
YML130C ERO1 Thiol oxidase required for oxidative protein folding in the endoplasmic reticulum Verified chr13:11484-13175 11484-13175 99.2% 266.86 211.46 279.37 235.29 1611.87 1210.99 239.16 257.33 1411.43 0.88 1.04 5.85 2.46 2.54 Matched[4214]
YML129C COX14 "Mitochondrial membrane protein, required for assembly of cytochrome c oxidase" Verified chr13:14542-14754 14542-14754 99.4% 538.37 538.37 760.33 580.87 1119.24 713.11 538.37 670.60 916.17 1.99 2.72 3.80 0.45 0.61 Matched[4216]
YML128C MSC1 "Protein of unknown function; mutant is defective in directing meiotic recombination events to homologous chromatids; the authentic, non-tagged protein is detected in highly purified mitochondria and is phosphorylated" Verified chr13:15136-16677 15136-16677 99.1% 176.03 600.74 301.02 397.87 4858.90 4514.68 388.38 349.45 4686.79 1.43 1.42 19.42 3.75 3.28 Frag>80[4216,4217,4218]
YML127W RSC9 Component of the RSC chromatin remodeling complex; DNA-binding protein involved in the synthesis of rRNA and in transcriptional repression and activation of genes regulated by the Target of Rapamycin (TOR) pathway Verified chr13:17065-18810 17065-18810 98.8% 189.62 187.30 209.92 161.79 374.02 332.85 188.46 185.85 353.44 0.70 0.75 1.46 0.93 0.88 Matched[4219]
YML126C ERG13 "3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase, catalyzes the formation of HMG-CoA from acetyl-CoA and acetoacetyl-CoA; involved in the second step in mevalonate biosynthesis" Verified chr13:19061-20536 19061-20536 99.0% 802.60 770.44 734.86 693.81 343.48 338.01 786.52 714.33 340.75 2.90 2.90 1.41 -1.07 -0.41 Matched[4220]
YML125C PGA3 "Essential protein required for maturation of Gas1p and Pho8p, protein trafficking; GFP-fusion protein localizes to the endoplasmic reticulum; null mutants have a cell separation defect" Uncharacterized chr13:20762-21700 20762-21700 98.8% 522.72 329.80 409.56 331.96 170.29 112.09 426.26 370.76 141.19 1.57 1.50 0.58 -1.39 -1.14 Matched[4221]
YML124C TUB3 "Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; expressed at lower level than Tub1p" Verified chr13:22049-23684 22049-23361,23660-23684 95.7% 556.30 514.89 541.46 548.49 501.61 463.33 535.60 544.98 482.47 1.98 2.21 2.00 -0.18 0.41 Frag>80[4222,4223,4224]
YML123C PHO84 High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter; regulated by Pho4p and Spt7p; mutation confers resistance to arsenate; exit from the ER during maturation requires Pho86p Verified chr13:24038-25801 24038-25801 98.7% 5122.96 5723.64 4859.38 3709.71 828.08 368.67 5423.30 4284.55 598.38 20.02 17.39 2.48 -2.84 -3.69 Matched[4225]
YML122C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr13:26039-26419 26039-26419 98.5% 18.65 18.65 10.66 10.66 13.32 26.64 18.65 10.66 19.98 0.07 0.04 0.08 0.91 0.21 Matched[4226]
YML121W GTR1 "Cytoplasmic GTP binding protein and negative regulator, with homolog Gtr2p, of the Ran/Tc4 GTPase cycle; component of GSE complex, which is required for sorting of Gap1p; involved in phosphate transport; has homology to human RagA and RagB" Verified chr13:26930-27862 26930-27862 98.8% 271.27 356.99 208.34 215.93 204.00 145.40 314.13 212.13 174.70 1.16 0.86 0.72 -0.28 -0.12 Matched[4227]
YML120C NDI1 "NADH:ubiquinone oxidoreductase, transfers electrons from NADH to ubiquinone in the respiratory chain but does not pump protons, in contrast to the higher eukaryotic multisubunit respiratory complex I; phosphorylated; homolog of human AMID" Verified chr13:28266-29807 28266-29807 98.8% 184.38 238.84 316.26 432.40 519.67 547.89 211.61 374.33 533.78 0.78 1.52 2.21 0.51 0.76 Matched[4228]
YML119W Putative protein of unknown funtion; YML119W is not an essential gene; potential Cdc28p substrate Uncharacterized chr13:30611-31684 30611-31684 98.7% 150.97 181.17 115.12 116.06 160.41 111.34 166.07 115.59 135.88 0.61 0.47 0.56 0.23 0.35 Matched[4230]
YML118W NGL3 "Putative endonuclease, has a domain similar to a magnesium-dependent endonuclease motif in mRNA deadenylase Ccr4p; similar to Ngl1p and Ngl2p" Verified chr13:32334-33851 32334-33851 98.6% 15.37 35.42 16.71 12.70 38.76 86.20 25.39 14.70 62.48 0.09 0.06 0.26 2.09 2.67 Matched[4231]
YML117W NAB6 "Putative RNA-binding protein, based on computational analysis of large-scale protein-protein interaction data" Verified chr13:34243-37647 34243-37647 98.7% 207.30 257.86 210.28 217.12 303.96 355.71 232.58 213.70 329.84 0.86 0.87 1.37 0.63 1.23 Matched[4232]
YML116W-A Putative protein of unknown function Dubious chr13:37472-37774 37472-37774 98.6% 421.58 585.53 394.81 361.36 953.58 669.18 503.55 378.08 811.38 1.86 1.53 3.36 1.10 1.22 Covered/w/another[4232]
YML116W ATR1 "Multidrug efflux pump of the major facilitator superfamily, required for resistance to aminotriazole and 4-nitroquinoline-N-oxide" Verified chr13:38196-39824 38196-39824 98.7% 110.06 96.38 95.14 54.72 44.15 14.30 103.22 74.93 29.23 0.38 0.30 0.12 -1.36 -1.33 Matched[4233]
YML115C VAN1 "Component of the mannan polymerase I, which contains Van1p and Mnn9p and is involved in the first steps of mannan synthesis; mutants are vanadate-resistant" Verified chr13:40187-41794 40187-41794 99.1% 283.55 277.28 289.82 268.49 176.90 183.18 280.41 279.16 180.04 1.04 1.13 0.75 -0.63 0.01 Matched[4234]
YML114C TAF8 "TFIID subunit (65 kDa), involved in RNA polymerase II transcription initiation" Verified chr13:42043-43575 42043-43575 98.9% 118.02 145.71 98.24 78.46 80.44 80.44 131.87 88.35 80.44 0.49 0.36 0.33 -0.14 0.55 Matched[4235]
YML113W DAT1 DNA binding protein that recognizes oligo(dA).oligo(dT) tracts; Arg side chain in its N-terminal pentad Gly-Arg-Lys-Pro-Gly repeat is required for DNA-binding; not essential for viability Verified chr13:44045-44791 44045-44791 96.7% 124.53 121.76 103.78 76.10 22.14 37.36 123.15 89.94 29.75 0.45 0.37 0.12 -1.60 -1.30 Covered/w/another[4236]
YML112W CTK3 "Gamma subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates the C-terminal repeated domain of the RNA polymerase II large subunit (Rpo21p) to affect both transcription and pre-mRNA 3' end processing" Verified chr13:45063-45953 45063-45953 98.7% 92.06 69.33 86.38 77.29 71.60 63.65 80.70 81.83 67.63 0.30 0.33 0.28 -0.28 0.39 Covered/w/another[4236]
YML111W BUL2 "Component of the Rsp5p E3-ubiquitin ligase complex, involved in intracellular amino acid permease sorting, functions in heat shock element mediated gene expression, essential for growth in stress conditions, functional homolog of BUL1" Verified chr13:46942-49704 46942-49704 99.0% 149.58 153.97 136.05 122.52 88.87 89.24 151.78 129.28 89.05 0.56 0.52 0.37 -0.54 -0.33 Matched[4237]
YML110C COQ5 "2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase, involved in ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes" Verified chr13:50031-50954 50031-50954 99.2% 1097.60 1565.67 1136.88 1149.97 1655.13 1604.95 1331.64 1143.43 1630.04 4.92 4.64 6.75 0.51 0.62 Frag>80[4238,4239,4240]
YML109W ZDS2 "Protein that interacts with silencing proteins at the telomere, involved in transcriptional silencing; paralog of Zds1p" Verified chr13:51640-54468 51640-54468 98.6% 68.09 50.89 50.89 46.23 26.16 21.50 59.49 48.56 23.83 0.22 0.20 0.10 -1.03 -0.17
YML108W Putative protein of unknown function whose structure defines a new subfamily of the split beta-alpha-beta sandwiches; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YML108W is not an essential gene Uncharacterized chr13:54793-55110 54793-55110 98.7% 127.49 130.68 114.74 114.74 57.37 19.12 129.08 114.74 38.25 0.48 0.47 0.16 -1.58 -1.48 Covered/w/another[4241]
YML107C PML39 Protein required for nuclear retention of unspliced pre-mRNAs along with Mlp1p and Pml1p; anchored to nuclear pore complex via Mlp1p and Mlp2p; found with the subset of nuclear pores farthest from the nucleolus; may interact with ribosomes Verified chr13:55265-56269 55265-56269 99.1% 102.38 74.27 73.27 75.28 72.26 48.18 88.32 74.27 60.22 0.33 0.30 0.25 -0.30 -0.04 Covered/w/another[4241]
YML106W URA5 "One of two orotate phosphoribosyltransferase isozymes (see also URA10) that catalyze the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate" Verified chr13:56773-57453 56773-57453 98.8% 1814.26 1326.89 1583.95 1457.65 508.17 393.76 1570.58 1520.80 450.97 5.80 6.17 1.87 -1.75 -1.90 Matched[4242]
YML105C SEC65 "Subunit of the signal recognition particle (SRP), involved in protein targeting to the ER; interacts with Srp54p; homolog of mammalian SRP19" Verified chr13:57866-58687 57866-58687 99.2% 392.52 356.95 316.47 359.40 236.74 210.98 374.73 337.93 223.86 1.38 1.37 0.93 -0.59 -0.51 Matched[4243]
YML104C MDM1 "Intermediate filament protein, required for nuclear and mitochondrial transmission to daughter buds; contains a Phox homology (PX) domain and specifically binds phosphatidylinositol 3-phosphate (PtdIns-3-P)" Verified chr13:58939-62322 58939-62322 99.2% 110.48 125.37 95.00 69.39 60.75 48.24 117.93 82.19 54.50 0.44 0.33 0.23 -0.59 -0.10 Matched[4244]
YML103C NUP188 "Subunit of the nuclear pore complex (NPC), involved in the structural organization of the complex and of the nuclear envelope, also involved in nuclear envelope permeability, interacts with Pom152p and Nic96p" Verified chr13:62582-67549 62582-67549 99.1% 162.10 132.24 121.88 124.72 83.89 82.67 147.17 123.30 83.28 0.54 0.50 0.35 -0.57 -0.34 Matched[4245]
YML102W CAC2 "Component of the chromatin assembly complex (with Rlf2p and Msi1p) that assembles newly synthesized histones onto recently replicated DNA, required for building functional kinetochores, conserved from yeast to humans" Verified chr13:68294-69700 68294-69700 98.1% 97.06 106.48 100.69 85.47 105.03 73.88 101.77 93.08 89.46 0.38 0.38 0.37 -0.06 0.09 Matched[4246]
YML101C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr13:69409-69726 69409-69726 98.2% 150.54 128.12 140.93 121.71 153.74 60.86 139.33 131.32 107.30 0.51 0.53 0.44 -0.29 0.82 Covered/w/another[4246]
YML101C CUE4 "Protein of unknown function; has a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination" Verified chr13:69735-70088 69735-70088 98.6% 177.59 137.49 220.55 171.86 501.25 295.02 157.54 196.20 398.14 0.58 0.80 1.65 1.02 0.86 Matched[4247]
YML100W-A "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr13:70138-70311 70138-70311 98.4% 5.84 5.84 11.68 0.00 110.98 40.89 5.84 5.84 75.93 0.02 0.02 0.31 3.70 NaN Matched[4248]
YML100W TSL1 "Large subunit of trehalose 6-phosphate synthase (Tps1p)/phosphatase (Tps2p) complex, which converts uridine-5'-diphosphoglucose and glucose 6-phosphate to trehalose, homologous to Tps3p and may share function" Verified chr13:70624-73920 70624-73920 98.8% 155.32 427.89 493.57 609.91 3810.15 4641.06 291.60 551.74 4225.61 1.08 2.24 17.51 2.94 2.89 Frag>80[4248,4249,4250,4251,4252]
YML099W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF ARG81/YML099C" Dubious chr13:74229-74558 74229-74558 99.7% 91.22 121.63 115.55 69.94 82.10 60.81 106.42 92.74 71.46 0.39 0.38 0.30 -0.38 0.15 Covered/w/another[4253]
YML099C ARG81 "Zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type, involved in the regulation of arginine-responsive genes; acts with Arg80p and Arg82p" Verified chr13:74398-77040 74398-77040 99.1% 73.68 78.27 64.14 53.07 51.16 64.52 75.97 58.60 57.84 0.28 0.24 0.24 -0.02 0.31 Matched[4253]
YML098W TAF13 "TFIID subunit (19 kDa), involved in RNA polymerase II transcription initiation, similar to histone H4 with atypical histone fold motif of Spt3-like transcription factors" Verified chr13:77267-77770 77267-77770 98.2% 230.42 272.87 226.38 220.31 192.02 117.23 251.64 223.35 154.62 0.93 0.91 0.64 -0.53 -0.49 Matched[4254]
YML097C VPS9 A guanine nucleotide exchange factor involved in vesicle-mediated vacuolar protein transport; specifically stimulates the intrinsic guanine nucleotide exchange activity of Vps21p/Rab5: similar to mammalian ras inhibitors; binds ubiquitin Verified chr13:78335-79690 78335-79690 99.2% 121.87 138.22 133.02 91.40 87.69 62.42 130.05 112.21 75.06 0.48 0.46 0.31 -0.58 -0.31 Matched[4256]
YML096W Putative protein of unknown function with similarity to asparagine synthetases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YML096W is not an essential gene and partially overlaps the verified gene RAD10 Uncharacterized chr13:79909-81486 79909-81486 98.8% 112.20 90.40 76.29 64.11 34.62 34.62 101.30 70.20 34.62 0.37 0.28 0.14 -1.02 -1.72 Frag>80[4257,4258]
YML095C RAD10 "Single-stranded DNA endonuclease (with Rad1p), cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human ERCC1 protein" Verified chr13:81481-82113 81481-82113 99.3% 66.82 52.50 42.95 66.82 103.41 60.45 59.66 54.89 81.93 0.22 0.22 0.34 0.58 0.75 Covered[4258]
YML094W GIM5 Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it Verified chr13:82275-82849 82275-82290,82374-82849 98.7% 325.52 222.51 220.45 255.47 162.76 84.47 274.01 237.96 123.62 1.01 0.97 0.51 -0.94 -0.98 Matched[4259]
YML094C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene GIM5/YML094W; deletion confers sensitivity to GSAO" Dubious chr13:82219-82620 82219-82620 98.9% 216.22 120.68 130.74 125.71 105.59 57.83 168.45 128.22 81.71 0.62 0.52 0.34 -0.65 -0.65 Matched[4259]
YML093W UTP14 "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" Verified chr13:83090-85789 83090-85789 98.2% 251.26 130.91 149.78 111.67 11.32 3.77 191.09 130.72 7.55 0.71 0.53 0.03 -4.11 -3.62 Matched[4260]
YML092C PRE8 20S proteasome beta-type subunit Verified chr13:85987-86739 85987-86739 98.9% 608.26 487.41 601.54 550.52 839.21 578.72 547.83 576.03 708.96 2.02 2.34 2.94 0.30 0.43 Matched[4261]
YML091C RPM2 "Protein subunit of mitochondrial RNase P, has roles in nuclear transcription, cytoplasmic and mitochondrial RNA processing, and mitochondrial translation; distributed to mitochondria, cytoplasmic processing bodies, and the nucleus" Verified chr13:87123-90731 87123-90731 99.1% 117.66 137.78 221.62 304.63 244.54 258.52 127.72 263.13 251.53 0.47 1.07 1.04 -0.07 0.41 Matched[4262]
YML090W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YML089C; exhibits growth defect on a non-fermentable (respiratory) carbon source" Dubious chr13:90744-91130 90744-91130 98.8% 60.14 83.68 138.59 203.97 109.83 133.36 71.91 171.28 121.60 0.27 0.70 0.50 -0.49 0.11 Covered/w/another[4262]
YML089C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; expression induced by calcium shortage" Dubious chr13:91041-91409 91041-91409 94.8% 8.58 8.58 5.72 2.86 2.86 8.58 8.58 4.29 5.72 0.03 0.02 0.02 0.42 -1.08 Overlap[4262]
YML088W UFO1 "F-box receptor protein, subunit of the Skp1-Cdc53-F-box receptor (SCF) E3 ubiquitin ligase complex; binds to phosphorylated Ho endonuclease, allowing its ubiquitylation by SCF and subsequent degradation" Verified chr13:92235-94241 92235-94241 98.5% 123.88 103.66 102.65 67.76 85.45 74.84 113.77 85.20 80.14 0.42 0.35 0.33 -0.09 0.08 Covered/w/another[4263]
YML087C Putative protein of unknown function Uncharacterized chr13:94431-95369 94431-95369 99.1% 40.82 63.38 50.49 54.79 42.97 35.45 52.10 52.64 39.21 0.19 0.21 0.16 -0.42 -0.19 Covered/w/another[4263]
YML086C ALO1 "D-Arabinono-1,4-lactone oxidase, catalyzes the final step in biosynthesis of D-erythroascorbic acid, which is protective against oxidative stress" Verified chr13:95791-97371 95791-97371 99.0% 366.64 305.96 395.38 394.10 279.13 245.28 336.30 394.74 262.20 1.24 1.60 1.09 -0.59 0.01 Matched[4264]
YML085C TUB1 "Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules" Verified chr13:97941-99400 97941-99259,99376-99400 95.4% 1069.28 1275.97 1052.91 1068.50 1024.05 937.48 1172.62 1060.70 980.76 4.33 4.31 4.06 -0.11 0.36 Frag>80[4265,4266]
YML084W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr13:99489-99797 99489-99797 99.2% 0.00 3.26 0.00 0.00 9.79 3.26 1.63 0.00 6.52 0.01 0.00 0.03 Inf 0.19 Overlap[4267]
YML083C Putative protein of unknown function; strong increase in transcript abundance during anaerobic growth compared to aerobic growth; cells deleted for YML083C do not exhibit growth defects in anerobic or anaerobic conditions Uncharacterized chr13:99794-101050 99794-101050 98.6% 6.45 24.20 8.87 12.91 29.85 37.92 15.33 10.89 33.88 0.06 0.04 0.14 1.64 2.13 Frag<80[4267]
YML082W Putative protein predicted to have carbon-sulfur lyase activity; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and the cytoplasm; YNML082W is not an essential gene Uncharacterized chr13:101862-103811 101862-103811 98.4% 105.28 91.21 77.14 58.89 14.07 16.16 98.24 68.01 15.11 0.36 0.28 0.06 -2.17 -1.29 Matched[4268]
YML081C-A ATP18 "Subunit of the mitochondrial F1F0 ATP synthase, which is a large enzyme complex required for ATP synthesis; termed subunit I or subunit j; does not correspond to known ATP synthase subunits in other organisms" Verified chr13:103983-104162 103983-104162 98.6% 1093.21 1121.39 1093.21 1160.84 1893.40 1143.93 1107.30 1127.03 1518.67 4.09 4.57 6.29 0.43 -0.41 Matched[4269]
YML081W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YML081w is not an essential gene Uncharacterized chr13:104777-108532 104777-108532 99.0% 130.39 135.76 95.71 83.88 51.35 52.15 133.07 89.79 51.75 0.49 0.36 0.21 -0.79 -0.61 Matched[4270]
YML080W DUS1 "Dihydrouridine synthase, member of a widespread family of conserved proteins including Smm1p, Dus3p, and Dus4p; modifies pre-tRNA(Phe) at U17" Verified chr13:108806-110077 108806-110077 98.5% 73.41 55.06 56.65 38.30 12.77 3.19 64.23 47.48 7.98 0.24 0.19 0.03 -2.57 -1.63 Matched[4271]
YML079W "Non-essential protein of unknown function with structural resemblance to plant storage and ligand binding proteins (canavalin, glycinin, auxin binding protein) and to some enzymes (epimerase, germin); localizes to the nucleus and cytoplasm" Uncharacterized chr13:110247-110852 110247-110852 98.6% 527.38 505.62 467.11 411.86 691.45 485.52 516.50 439.48 588.49 1.91 1.78 2.44 0.42 1.30 Covered/w/another[4272]
YML078W CPR3 "Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; involved in protein refolding after import into mitochondria" Verified chr13:111002-111550 111002-111550 98.6% 923.50 1073.11 873.63 886.56 1102.66 788.67 998.31 880.10 945.67 3.69 3.57 3.92 0.10 0.20 Matched[4272]
YML077W BET5 "Component of the TRAPP (transport protein particle) complex, which plays an essential role in the vesicular transport from endoplasmic reticulum to Golgi" Verified chr13:111865-112344 111865-112344 98.7% 253.32 192.10 189.99 206.88 236.43 168.88 222.71 198.43 202.66 0.82 0.81 0.84 0.03 0.08 Matched[4273]
YML076C WAR1 "Homodimeric Zn2Cys6 zinc finger transcription factor; binds to a weak acid response element to induce transcription of PDR12 and FUN34, encoding an acid transporter and a putative ammonia transporter, respectively" Verified chr13:112513-115347 112513-115347 99.1% 65.16 63.02 46.29 35.25 46.29 63.38 64.09 40.77 54.83 0.24 0.17 0.23 0.43 0.93 Matched[4274]
YML075C HMG1 "One of two isozymes of HMG-CoA reductase that catalyzes the conversion of HMG-CoA to mevalonate, which is a rate-limiting step in sterol biosynthesis; localizes to the nuclear envelope; overproduction induces the formation of karmellae" Verified chr13:115734-118898 115734-118898 98.5% 149.46 150.11 129.58 83.39 62.22 50.04 149.79 106.49 56.13 0.55 0.43 0.23 -0.92 -0.23 Covered[4275]
YML074C FPR3 Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; phosphorylated by casein kinase II (Cka1p-Cka2p-Ckb1p-Ckb2p) and dephosphorylated by Ptp1p Verified chr13:120089-121324 120089-121324 98.6% 1968.33 1399.50 1604.71 1548.07 1598.14 1700.74 1683.92 1576.39 1649.44 6.22 6.40 6.83 0.07 0.22 Frag>80[4276,4277]
YML073C RPL6A "N-terminally acetylated protein component of the large (60S) ribosomal subunit, has similarity to Rpl6Bp and to rat L6 ribosomal protein; binds to 5.8S rRNA" Verified chr13:123227-124172 123227-123742,124158-124172 85.5% 7186.79 6099.08 6063.85 5209.54 1226.42 673.76 6642.94 5636.70 950.09 24.52 22.88 3.94 -2.57 -3.14 Matched[4280]
YML072C TCB3 "Lipid-binding protein, localized to the bud via specific mRNA transport; non-tagged protein detected in a phosphorylated state in mitochondria; GFP-fusion protein localizes to the cell periphery; C-termini of Tcb1p, Tcb2p and Tcb3p interact" Verified chr13:124730-129367 124730-129367 99.1% 347.74 509.87 407.15 395.62 261.13 423.91 428.80 401.39 342.52 1.58 1.63 1.42 -0.23 0.52 Frag>80[4281,4282,4283]
YML071C COG8 "Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" Verified chr13:129749-131572 129749-131572 97.3% 166.84 144.30 149.37 125.70 175.86 148.81 155.57 137.53 162.33 0.57 0.56 0.67 0.24 0.58 Matched[4284]
YML070W DAK1 "Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress adaptation" Verified chr13:133475-135229 133475-135229 98.7% 334.42 515.79 382.36 373.70 1092.22 933.38 425.11 378.03 1012.80 1.57 1.53 4.20 1.42 1.87 Matched[4285]
YML069W POB3 "Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), which facilitates RNA Pol II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure; interacts with DNA polymerase alpha (Pol1p)" Verified chr13:135500-137158 135500-137158 98.5% 417.27 417.27 472.95 428.29 284.51 218.43 417.27 450.62 251.47 1.54 1.83 1.04 -0.84 -0.65 Matched[4286]
YML068W ITT1 "Protein that modulates the efficiency of translation termination, interacts with translation release factors eRF1 (Sup45p) and eRF3 (Sup35p) in vitro, contains a zinc finger domain characteristic of the TRIAD class of proteins" Verified chr13:137550-138944 137550-138944 98.6% 80.70 88.70 80.70 71.98 123.60 76.34 84.70 76.34 99.97 0.31 0.31 0.41 0.39 0.20 Matched[4287]
YML067C ERV41 "Protein localized to COPII-coated vesicles, forms a complex with Erv46p; involved in the membrane fusion stage of transport; has homology to human ERGIC2 (PTX1) protein" Verified chr13:139063-140214 139063-140090,140184-140214 99.1% 361.18 338.31 363.09 303.05 386.91 219.19 349.75 333.07 303.05 1.29 1.35 1.26 -0.14 -0.41 Matched[4288]
YML066C SMA2 Protein of unknown function involved in the assembly of the prospore membrane during sporulation Verified chr13:140424-141533 140424-141533 99.1% 14.55 20.01 14.55 10.00 30.01 17.28 17.28 12.28 23.64 0.06 0.05 0.10 0.95 0.81
YML065W ORC1 "Largest subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; exhibits ATPase activity" Verified chr13:142210-144954 142210-144954 98.5% 107.28 84.34 86.19 72.14 91.37 85.82 95.81 79.16 88.60 0.35 0.32 0.37 0.16 0.32 Covered/w/another[4289]
YML064C TEM1 GTP-binding protein of the ras superfamily involved in termination of M-phase; controls actomyosin and septin dynamics during cytokinesis Verified chr13:145139-145876 145139-145876 99.1% 116.18 120.28 139.42 98.41 158.55 88.84 118.23 118.91 123.70 0.44 0.48 0.51 0.06 0.23 Covered/w/another[4289]
YML063W RPS1B Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Ap and has similarity to rat S3a ribosomal protein Verified chr13:146482-147249 146482-147249 73.6% 10429.17 7800.22 8707.18 7234.48 1729.06 1440.88 9114.70 7970.83 1584.97 33.65 32.36 6.57 -2.33 -2.16 Matched[4290]
YML062C MFT1 "Subunit of the THO complex, which is a nuclear complex comprised of Hpr1p, Mft1p, Rlr1p, and Thp2p, that is involved in transcription elongation and mitotic recombination; involved in telomere maintenance" Verified chr13:147505-148683 147505-148683 99.5% 142.39 168.82 155.18 131.31 196.11 123.63 155.61 143.24 159.87 0.57 0.58 0.66 0.16 -0.13 Covered/w/another[4291]
YML061C PIF1 DNA helicase involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; also plays a role in repair and recombination of mitochondrial DNA Verified chr13:148953-151532 148953-151532 99.2% 105.51 83.24 98.09 75.03 60.96 38.30 94.37 86.56 49.63 0.35 0.35 0.21 -0.80 -0.37 Covered/w/another[4291]
YML060W OGG1 "Mitochondrial glycosylase/lyase that specifically excises 7,8-dihydro-8-oxoguanine residues located opposite cytosine or thymine residues in DNA, repairs oxidative damage to mitochondrial DNA" Verified chr13:151871-153001 151871-153001 98.6% 76.24 54.71 74.45 53.82 23.32 7.18 65.48 64.13 15.25 0.24 0.26 0.06 -2.07 -2.05 Matched[4292]
YML059C NTE1 "Serine esterase that deacylates exogenous lysophospholipids, homolog of human neuropathy target esterase (NTE); mammalian NTE1 deacylates phosphatidylcholine to glycerophosphocholine" Verified chr13:153219-158258 153219-158258 98.8% 105.99 138.51 119.64 89.13 71.26 114.02 122.25 104.38 92.64 0.45 0.42 0.38 -0.17 0.52 Matched[4293]
YML058W-A HUG1 "Protein involved in the Mec1p-mediated checkpoint pathway that responds to DNA damage or replication arrest, transcription is induced by DNA damage" Verified chr13:158760-158966 158760-158966 99.0% 9.76 58.57 4.88 9.76 34.17 29.29 34.17 7.32 31.73 0.13 0.03 0.13 2.12 0.83
YML058W SML1 Ribonucleotide reductase inhibitor involved in regulating dNTP production; regulated by Mec1p and Rad53p during DNA damage and S phase Verified chr13:159383-159697 159383-159697 98.9% 1891.36 1955.58 2042.28 1666.58 3924.00 2511.10 1923.47 1854.43 3217.55 7.10 7.53 13.33 0.79 0.67 Matched[4294]
YML057W CMP2 "Calcineurin A; one isoform (the other is CNA1) of the catalytic subunit of calcineurin, a Ca++/calmodulin-regulated protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is CNB1" Verified chr13:160180-161994 160180-161994 98.7% 203.16 242.79 263.44 237.77 360.00 305.86 222.98 250.60 332.93 0.82 1.02 1.38 0.41 0.76 Matched[4295]
YML057C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene CMP2/YML057W" Dubious chr13:160023-160412 160023-160412 98.9% 103.74 111.52 137.45 150.42 160.80 173.76 107.63 143.94 167.28 0.40 0.58 0.69 0.22 -0.06 Covered/w/another[4295]
YML056C IMD4 "Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, member of a four-gene family in S. cerevisiae, constitutively expressed" Verified chr13:162194-164176 162194-163308,163717-164176 80.9% 1141.03 873.43 844.39 700.00 94.95 43.16 1007.23 772.19 69.06 3.72 3.13 0.29 -3.48 -3.12 Frag>80[4296,4297]
YML055W SPC2 "Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway; homologous to mammalian SPC25" Verified chr13:164790-165326 164790-165326 98.7% 460.34 450.91 339.60 356.58 320.73 209.42 455.62 348.09 265.07 1.68 1.41 1.10 -0.39 -0.90 Matched[4298]
YML054C CYB2 "Cytochrome b2 (L-lactate cytochrome-c oxidoreductase), component of the mitochondrial intermembrane space, required for lactate utilization; expression is repressed by glucose and anaerobic conditions" Verified chr13:165533-167308 165533-167308 99.0% 25.02 40.38 43.79 38.67 329.30 266.17 32.70 41.23 297.74 0.12 0.17 1.23 2.85 3.11 Covered/w/another[4299]
YML054C-A Putative protein of unknown function Uncharacterized chr13:167623-167781 167623-167781 98.0% 6.42 38.50 32.09 12.83 25.67 25.67 22.46 22.46 25.67 0.08 0.09 0.11 0.19 NaN Covered/w/another[4299]
YML053C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus; YML053C is not an essential gene Uncharacterized chr13:169116-169754 169116-169754 97.3% 320.13 273.48 307.26 299.22 278.30 267.04 296.80 303.24 272.67 1.10 1.23 1.13 -0.15 0.26 Frag>80[4300,4301,4302,4303]
YML052W SUR7 "Putative integral membrane protein; component of eisosomes; associated with endocytosis, along with Pil1p and Lsp1p; sporulation and plasma membrane sphingolipid content are altered in mutants" Verified chr13:170402-171310 170402-171310 98.7% 665.18 700.84 711.98 655.15 674.09 545.96 683.01 683.57 610.03 2.52 2.77 2.53 -0.16 0.03 Matched[4304]
YML051W GAL80 Transcriptional regulator involved in the repression of GAL genes in the absence of galactose; inhibits transcriptional activation by Gal4p; inhibition relieved by Gal3p or Gal1p binding Verified chr13:171594-172901 171594-172901 99.0% 251.83 244.87 281.95 242.56 179.21 149.86 248.35 262.25 164.54 0.92 1.06 0.68 -0.67 -0.16 Covered/w/another[4305]
YML050W Putative protein of unknown function; non-essential gene Uncharacterized chr13:173139-174074 173139-174074 98.8% 41.09 42.17 60.55 51.90 97.31 43.25 41.63 56.23 70.28 0.15 0.23 0.29 0.32 0.24 Covered/w/another[4305]
YML049C RSE1 Protein involved in pre-mRNA splicing; component of the pre-spliceosome; associates with U2 snRNA; involved in ER to Golgi transport Verified chr13:174220-178305 174220-178305 98.8% 100.54 82.47 79.49 83.46 95.34 100.79 91.50 81.48 98.07 0.34 0.33 0.41 0.27 0.60
YML048W GSF2 "ER localized integral membrane protein that may promote secretion of certain hexose transporters, including Gal2p; involved in glucose-dependent repression" Verified chr13:178426-179637 178426-179637 98.7% 770.07 602.01 930.60 881.27 744.15 618.73 686.04 905.94 681.44 2.53 3.68 2.82 -0.41 0.05 Matched[4306]
YML047W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr13:179893-180258 179893-180258 99.5% 35.71 16.48 19.23 13.74 19.23 8.24 26.10 16.48 13.74 0.10 0.07 0.06 -0.26 0.11 Matched[4307]
YML047C PRM6 "Pheromone-regulated protein, predicted to have 2 transmembrane segments; regulated by Ste12p during mating" Verified chr13:180017-181075 180017-181075 99.4% 11.40 10.45 7.60 9.50 3.80 4.75 10.93 8.55 4.28 0.04 0.03 0.02 -1.00 -1.20 Frag<80[4307]
YML046W PRP39 "U1 snRNP protein involved in splicing, contains multiple tetriatricopeptide repeats" Verified chr13:181474-183363 181474-183363 99.1% 132.97 124.96 125.50 113.21 51.80 44.32 128.97 119.35 48.06 0.48 0.48 0.20 -1.31 -0.82 Matched[4308]
YML043C RRN11 "Protein required for rDNA transcription by RNA polymerase I, component of the core factor (CF) of rDNA transcription factor, which also contains Rrn6p and Rrn7p" Verified chr13:190244-191767 190244-191767 99.3% 125.49 110.30 52.18 67.37 12.55 15.85 117.90 59.77 14.20 0.44 0.24 0.06 -2.07 -2.10 Matched[4309]
YML042W CAT2 "Carnitine acetyl-CoA transferase present in both mitochondria and peroxisomes, transfers activated acetyl groups to carnitine to form acetylcarnitine which can be shuttled across membranes" Verified chr13:192788-194800 192788-194800 98.9% 20.59 36.66 21.09 26.62 178.79 149.16 28.63 23.85 163.97 0.11 0.10 0.68 2.78 2.20 Matched[4311]
YML041C VPS71 "Nucleosome-binding component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required for vacuolar protein sorting" Verified chr13:194913-195755 194913-195755 99.2% 76.53 76.53 90.88 68.16 110.01 66.96 76.53 79.52 88.49 0.28 0.32 0.37 0.15 0.50 Matched[4312]
YML038C YMD8 "Putative nucleotide sugar transporter, has similarity to Vrg4p" Verified chr13:202775-204103 202775-204103 98.9% 253.99 219.77 245.63 165.78 153.61 137.64 236.88 205.70 145.63 0.87 0.83 0.60 -0.50 -0.13 Matched[4314]
YML037C Putative protein of unknown function with some characteristics of a transcriptional activator; may be a target of Dbf2p-Mob1p kinase; GFP-fusion protein co-localizes with clathrin-coated vesicles; YML037C is not an essential gene Uncharacterized chr13:204386-205408 204386-205408 99.1% 17.75 31.55 23.66 20.70 4.93 6.90 24.65 22.18 5.92 0.09 0.09 0.02 -1.91 -0.08 Frag<80[4315]
YML036W CGI121 "Protein involved in telomere uncapping and elongation as component of the KEOPS protein complex with Bud32p, Kae1p, Pcc1p, and Gon7p; also shown to be a component of the EKC protein complex; homolog of human CGI-121" Verified chr13:205642-206293 205642-206097,206204-206293 98.8% 198.42 159.48 157.63 114.97 191.01 70.47 178.95 136.30 130.74 0.66 0.55 0.54 -0.06 -0.31 Matched[4316]
YML035C AMD1 "AMP deaminase, tetrameric enzyme that catalyzes the deamination of AMP to form IMP and ammonia; may be involved in regulation of intracellular adenine nucleotide pools" Verified chr13:206428-208860 206428-208860 99.0% 268.62 240.81 259.90 233.33 240.39 291.46 254.71 246.62 265.92 0.94 1.00 1.10 0.11 0.70 Matched[4317]
YML034W SRC1 "Inner nuclear membrane (INM) protein with a putative role in sister chromatid segregation, potentially phosphorylated by Cdc28p; contains helix-extension-helix (HEH) motif, nuclear localization signal sequence" Verified chr13:209525-212155 209525-211444,211571-212155 97.9% 128.89 151.33 113.39 108.91 164.79 131.75 140.11 111.15 148.27 0.52 0.45 0.61 0.42 0.66 Covered/w/another[4318]
YML034C-A "Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr13:209428-209826 209428-209826 98.1% 76.64 107.29 48.54 38.32 58.75 56.20 91.96 43.43 57.48 0.34 0.18 0.24 0.40 0.24 Covered/w/another[4318]
YML032C RAD52 Protein that stimulates strand exchange by facilitating Rad51p binding to single-stranded DNA; anneals complementary single-stranded DNA; involved in the repair of double-strand breaks in DNA during vegetative growth and meiosis Verified chr13:212515-213930 212515-213930 99.1% 121.83 104.02 136.08 107.58 210.89 176.69 112.93 121.83 193.79 0.42 0.49 0.80 0.67 0.97 Covered/w/another[4318]
YML031W NDC1 "Nuclear envelope protein with multiple putative transmembrane domains, required for nuclear pore complex assembly and spindle pole body duplication; required for meiosis II" Verified chr13:214189-216156 214189-216156 98.8% 237.13 210.90 194.95 166.15 103.39 80.76 224.02 180.55 92.08 0.83 0.73 0.38 -0.97 -0.35 Matched[4319]
YML031C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF NDC1/YML031W; questionable ORF from MIPS" Dubious chr13:214086-214421 214086-214421 98.5% 84.56 114.76 69.46 81.54 36.24 42.28 99.66 75.50 39.26 0.37 0.31 0.16 -0.94 NaN Covered/w/another[4319]
YML030W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YML030W is not an essential gene Uncharacterized chr13:216435-216914 216435-216914 97.9% 451.18 393.72 415.00 385.21 563.98 204.31 422.45 400.11 384.14 1.56 1.62 1.59 -0.06 -0.30 Frag>80[4320,4321]
YML029W USA1 "Protein involved in ER-associated protein degradation (ERAD); component of the Hrd1p complex; interacts with the U1 snRNP-specific protein, Snp1p" Verified chr13:217362-219878 217362-219878 98.8% 82.07 83.28 75.23 76.04 94.14 113.45 82.68 75.64 103.80 0.31 0.31 0.43 0.46 1.33 Matched[4322]
YML028W TSA1 "Ubiquitous housekeeping thioredoxin peroxidase, reduces reactive oxygen, nitrogen and sulfur species using thioredoxin as hydrogen donor; mediates redox regulation of the nuclear localization of Yap1p; deletion results in mutator phenotype" Verified chr13:220138-220728 220138-220728 98.7% 9447.74 4005.43 8724.16 6136.74 11997.43 7055.80 6726.58 7430.45 9526.61 24.83 30.16 39.47 0.36 -0.36 Frag>80[4323,4324]
YML027W YOX1 "Homeodomain-containing transcriptional repressor, binds to Mcm1p and to early cell cycle boxes (ECBs) in the promoters of cell cycle-regulated genes expressed in M/G1 phase; expression is cell cycle-regulated; potential Cdc28p substrate" Verified chr13:221406-222563 221406-222563 98.7% 171.43 166.19 127.70 93.59 44.61 24.49 168.81 110.65 34.55 0.62 0.45 0.14 -1.68 -1.51 Matched[4325]
YML026C RPS18B Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Ap and has similarity to E. coli S13 and rat S18 ribosomal proteins Verified chr13:222987-223828 222987-223380,223782-223828 54.2% 8602.83 6199.90 7434.85 6392.46 1255.89 766.09 7401.36 6913.66 1010.99 27.32 28.06 4.19 -2.77 -3.94 Frag>80[4326,4327]
YML025C YML6 "Mitochondrial ribosomal protein of the large subunit, has similarity to E. coli L4 ribosomal protein and human mitoribosomal MRP-L4 protein; essential for viability, unlike most other mitoribosomal proteins" Verified chr13:224406-225365 224406-225239,225339-225365 98.8% 199.75 215.02 217.37 232.64 278.47 191.52 207.38 225.01 234.99 0.77 0.91 0.97 0.06 0.61 Matched[4328]
YML024W RPS17A Ribosomal protein 51 (rp51) of the small (40s) subunit; nearly identical to Rps17Bp and has similarity to rat S17 ribosomal protein Verified chr13:225889-226697 225889-225891,226290-226697 46.8% 11068.92 8296.49 9726.92 7901.17 2814.04 2299.09 9682.71 8814.04 2556.57 35.74 35.78 10.59 -1.79 -3.00 Matched[4329]
YML023C NSE5 Essential subunit of the Mms21-Smc5-Smc6 complex; required for cell viability and DNA repair Verified chr13:226994-228664 226994-228664 99.2% 108.60 124.89 71.80 68.18 50.68 37.41 116.75 69.99 44.04 0.43 0.28 0.18 -0.67 -0.53 Matched[4330]
YML022W APT1 "Adenine phosphoribosyltransferase, catalyzes the formation of AMP from adenine and 5-phosphoribosylpyrophosphate; involved in the salvage pathway of purine nucleotide biosynthesis" Verified chr13:228937-229500 228937-229500 98.8% 794.92 489.87 583.18 565.23 156.11 96.90 642.39 574.21 126.50 2.37 2.33 0.52 -2.18 -1.89 Matched[4331]
YML021C UNG1 "Uracil-DNA glycosylase, required for repair of uracil in DNA formed by spontaneous cytosine deamination, not required for strand-specific mismatch repair, cell-cycle regulated, expressed in late G1, localizes to mitochondria and nucleus" Verified chr13:229734-230813 229734-230813 99.1% 185.03 192.51 184.10 156.06 173.82 165.41 188.77 170.08 169.61 0.70 0.69 0.70 -0.00 -0.09 Matched[4332]
YML020W Putative protein of unknown function Uncharacterized chr13:231149-233143 231149-233143 98.7% 71.12 87.37 74.16 79.75 73.66 82.29 79.24 76.96 77.97 0.29 0.31 0.32 0.02 0.56 Covered/w/another[4333]
YML019W OST6 "Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; similar to and partially functionally redundant with Ost3p" Verified chr13:233457-234455 233457-234455 99.1% 270.81 229.38 279.90 204.12 143.49 91.95 250.09 242.01 117.72 0.92 0.98 0.49 -1.04 -0.98
YML018C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the membrane of the vacuole; YML018C is not an essential gene Uncharacterized chr13:234771-235952 234771-235952 98.7% 301.74 321.45 233.16 176.58 66.00 58.29 311.59 204.87 62.15 1.15 0.83 0.26 -1.72 -1.47 Matched[4334]
YML017W PSP2 Asn rich cytoplasmic protein that contains RGG motifs; high-copy suppressor of group II intron-splicing defects of a mutation in MRS2 and of a conditional mutation in POL1 (DNA polymerase alpha); possible role in mitochondrial mRNA splicing Verified chr13:236588-238731 236588-236591,236954-238731 97.6% 193.70 223.01 168.98 154.61 78.74 97.14 208.35 161.80 87.94 0.77 0.66 0.36 -0.88 -0.45 Covered/w/another[4335]
YML016C PPZ1 "Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance" Verified chr13:239458-241536 239458-241536 98.9% 161.45 152.70 128.87 95.80 102.61 75.38 157.08 112.34 88.99 0.58 0.46 0.37 -0.34 -0.20 Covered/w/another[4335]
YML015C TAF11 "TFIID subunit (40 kDa), involved in RNA polymerase II transcription initiation, similar to histone H3 with atypical histone fold motif of Spt3-like transcription factors" Verified chr13:241989-243029 241989-243029 99.1% 165.79 148.34 129.92 127.01 123.13 92.11 157.07 128.46 107.62 0.58 0.52 0.45 -0.26 0.18 Matched[4336]
YML014W TRM9 "tRNA methyltransferase, catalyzes the esterification of modified uridine nucleotides in tRNAs, creating 5-methylcarbonylmethyluridine in tRNA(Arg3) and 5-methylcarbonylmethyl-2-thiouridine in tRNA(Glu); may have a role in stress response" Verified chr13:243225-244064 243225-244064 98.2% 146.75 104.30 93.39 72.77 42.45 27.89 125.52 83.08 35.17 0.46 0.34 0.15 -1.24 -0.88 Covered/w/another[4337]
YML013W UBX2 Protein involved in ER-associated protein degradation; proposed to coordinate the assembly of proteins involved in ERAD; contains a UBX (ubiquitin regulatory X) domain and a ubiquitin-associated (UBA) domain Verified chr13:244149-245903 244149-245903 98.6% 132.90 175.66 122.50 139.26 152.55 202.82 154.28 130.88 177.68 0.57 0.53 0.74 0.44 1.05 Covered/w/another[4337]
YML012C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene SEL1" Dubious chr13:245537-245914 245537-245914 98.4% 177.42 223.12 155.91 177.42 268.82 231.18 200.27 166.67 250.00 0.74 0.68 1.04 0.58 0.29 Covered/w/another[4337]
YML012W ERV25 "Protein that forms a heterotrimeric complex with Erp1, Erp2p, and Emp24, member of the p24 family involved in endoplasmic reticulum to Golgi transport" Verified chr13:246116-246751 246116-246751 98.4% 1602.88 1633.24 1582.10 1537.36 2433.88 1483.02 1618.06 1559.73 1958.45 5.97 6.33 8.11 0.33 -0.66 Matched[4338]
YML011C RAD33 Protein involved in nucleotide excision repair; green fluorescent protein (GFP)-fusion protein localizes to the nucleus Verified chr13:246895-247428 246895-247428 99.3% 132.03 98.08 109.40 98.08 122.60 56.59 115.06 103.74 89.59 0.42 0.42 0.37 -0.21 -0.53 Matched[4339]
YML010W SPT5 Protein that forms a complex with Spt4p and mediates both activation and inhibition of transcription elongation; Spt4p-Spt5p complex also plays a role in pre-mRNA processing Verified chr13:247677-250868 247677-250868 98.0% 373.26 326.28 351.85 340.98 110.25 186.63 349.77 346.41 148.44 1.29 1.41 0.62 -1.22 -0.21 Matched[4340]
YML009W-B "Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr13:250435-250911 250435-250911 97.9% 629.72 541.90 708.97 561.18 299.87 321.29 585.81 635.07 310.58 2.16 2.58 1.29 -1.03 -0.35 Covered/w/another[4340]
YML009C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr13:250675-251001 250675-251001 98.7% 734.41 632.15 715.82 647.64 331.57 356.36 683.28 681.73 343.96 2.52 2.77 1.43 -0.99 -0.55 Covered/w/another[4340]
YML009C MRPL39 Mitochondrial ribosomal protein of the large subunit Verified chr13:251304-251516 251304-251516 99.1% 781.37 672.45 719.81 653.51 857.14 530.39 726.91 686.66 693.76 2.68 2.79 2.87 0.01 -0.30 Matched[4341]
YML008C ERG6 "Delta(24)-sterol C-methyltransferase, converts zymosterol to fecosterol in the ergosterol biosynthetic pathway by methylating position C-24; localized to both lipid particles and mitochondrial outer membrane" Verified chr13:251839-252990 251839-252990 99.2% 1035.49 1124.77 998.72 891.06 506.80 383.38 1080.13 944.89 445.09 3.99 3.84 1.84 -1.09 -0.36 Frag>80[4342,4343]
YML007C-A Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria Uncharacterized chr13:253162-253272 253162-253272 98.2% 36.71 27.53 27.53 27.53 64.24 18.36 32.12 27.53 41.30 0.12 0.11 0.17 0.58 1.09 Covered/w/another[4344]
YML007W YAP1 Basic leucine zipper (bZIP) transcription factor required for oxidative stress tolerance; activated by H2O2 through the multistep formation of disulfide bonds and transit from the cytoplasm to the nucleus; mediates resistance to cadmium Verified chr13:253848-255800 253848-255800 98.7% 232.95 194.04 212.72 176.40 315.96 213.75 213.49 194.56 264.86 0.79 0.79 1.10 0.45 0.48 Covered/w/another[4344]
YML006C GIS4 "CAAX box containing protein of unknown function, proposed to be involved in the RAS/cAMP signaling pathway" Verified chr13:256092-258416 256092-258416 99.2% 84.55 79.78 69.81 56.37 45.09 29.48 82.17 63.09 37.29 0.30 0.26 0.15 -0.76 -0.12 Matched[4345]
YML005W TRM12 S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; required for wybutosine formation in phenylalanine-accepting tRNA Verified chr13:260221-261609 260221-261609 99.0% 64.73 64.00 45.82 36.37 43.64 27.64 64.37 41.09 35.64 0.24 0.17 0.15 -0.21 0.11 Frag>80[4346,4347]
YML004C GLO1 "Monomeric glyoxalase I, catalyzes the detoxification of methylglyoxal (a by-product of glycolysis) via condensation with glutathione to produce S-D-lactoylglutathione; expression regulated by methylglyoxal levels and osmotic stress" Verified chr13:261705-262685 261705-262685 99.0% 598.97 760.55 613.38 658.66 2671.70 2021.27 679.76 636.02 2346.48 2.51 2.58 9.72 1.88 1.73 Frag>80[4347,4348]
YML003W Putative protein of unknown function Uncharacterized chr13:263483-264355 263483-264355 99.2% 34.66 41.59 21.95 33.50 53.14 71.62 38.12 27.73 62.38 0.14 0.11 0.26 1.17 1.72 Covered/w/another[4349]
YML002W Putative protein of unknown function; expression induced by heat and by calcium shortage Uncharacterized chr13:264541-266754 264541-266754 98.9% 84.92 87.66 57.98 57.53 115.51 77.62 86.29 57.76 96.56 0.32 0.23 0.40 0.74 0.96 Covered/w/another[4349]
YML001W YPT7 "GTPase; GTP-binding protein of the rab family; required for homotypic fusion event in vacuole inheritance, for endosome-endosome fusion, similar to mammalian Rab7" Verified chr13:267174-267800 267174-267800 98.9% 921.28 864.81 872.87 855.13 1063.26 622.79 893.04 864.00 843.03 3.30 3.51 3.49 -0.04 -0.61 Frag>80[4350,4351]
YMR001C CDC5 "Polo-like kinase with similarity to Xenopus Plx1 and S. pombe Plo1p; found at bud neck, nucleus and SPBs; has multiple functions in mitosis and cytokinesis through phosphorylation of substrates; may be a Cdc28p substrate" Verified chr13:269019-271136 269019-271136 99.2% 251.77 226.07 187.52 168.01 146.59 60.92 238.92 177.76 103.75 0.88 0.72 0.43 -0.78 -0.91 Matched[4352]
YMR001C-A Putative protein of unknown function Uncharacterized chr13:271347-271577 271347-271577 98.9% 65.68 87.58 70.06 87.58 65.68 52.55 76.63 78.82 59.11 0.28 0.32 0.24 -0.42 NaN Covered/w/another[4352]
YMR002W MIC17 Mitochondrial intermembrane space cysteine motif protein; MIC17 is not an essential gene Verified chr13:272193-272663 272193-272663 98.7% 1040.77 832.18 1010.66 974.11 1614.91 1004.21 936.48 992.38 1309.56 3.46 4.03 5.43 0.40 0.34 Matched[4353]
YMR003W Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondria; YMR003W is not an essential gene Uncharacterized chr13:273118-273714 273118-273714 99.0% 133.62 111.63 123.47 101.48 86.26 38.90 122.62 112.47 62.58 0.45 0.46 0.26 -0.85 -1.16 Matched[4354]
YMR004W MVP1 Protein required for sorting proteins to the vacuole; overproduction of Mvp1p suppresses several dominant VPS1 mutations; Mvp1p and Vps1p act in concert to promote membrane traffic to the vacuole Verified chr13:274017-275552 274017-275552 98.7% 158.95 149.06 131.91 146.42 212.38 171.49 154.01 139.17 191.93 0.57 0.56 0.80 0.46 0.81 Matched[4355]
YMR005W TAF4 "TFIID subunit (48 kDa), involved in RNA polymerase II transcription initiation; potential Cdc28p substrate" Verified chr13:276045-277211 276045-277211 98.5% 243.64 274.96 247.12 218.40 214.05 216.66 259.30 232.76 215.36 0.96 0.94 0.89 -0.11 0.18 Matched[4356]
YMR006C PLB2 Phospholipase B (lysophospholipase) involved in phospholipid metabolism; displays transacylase activity in vitro; overproduction confers resistance to lysophosphatidylcholine Verified chr13:277561-279681 277561-279681 96.6% 177.69 503.28 194.28 203.56 53.70 45.89 340.49 198.92 49.79 1.26 0.81 0.21 -2.00 -1.75 Matched[4357]
YMR007W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr13:279960-280340 279960-280340 98.7% 74.47 117.02 58.51 29.26 47.87 15.96 95.74 43.88 31.91 0.35 0.18 0.13 -0.46 -0.22 Covered/w/another[4357]
YMR008C PLB1 "Phospholipase B (lysophospholipase) involved in lipid metabolism, required for deacylation of phosphatidylcholine and phosphatidylethanolamine but not phosphatidylinositol" Verified chr13:280590-282584 280590-282584 96.6% 273.86 398.34 276.45 284.75 216.29 255.71 336.10 280.60 236.00 1.24 1.14 0.98 -0.25 0.26 Matched[4358]
YMR009W ADI1 Acireductone dioxygenease involved in the methionine salvage pathway; ortholog of human MTCBP-1; transcribed with YMR010W and regulated post-transcriptionally by RNase III (Rnt1p) cleavage; ADI1 mRNA is induced in heat shock conditions Verified chr13:284101-284640 284101-284640 98.7% 99.47 140.76 125.74 121.99 320.93 208.32 120.11 123.87 264.62 0.44 0.50 1.10 1.10 0.96 Covered/w/another[4360]
YMR010W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YMR010W is not an essential gene; YMR010W mRNA is transcribed with ADI1 Uncharacterized chr13:285099-286316 285099-286316 99.1% 255.17 265.94 270.91 236.11 186.41 136.70 260.55 253.51 161.55 0.96 1.03 0.67 -0.65 -0.43 Covered/w/another[4360]
YMR011W HXT2 "High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose" Verified chr13:288078-289703 288078-289703 97.6% 214.92 115.97 1021.01 833.19 165.76 43.49 165.44 927.10 104.62 0.61 3.76 0.43 -3.15 -3.30 Matched[4361]
YMR012W CLU1 "eIF3 component of unknown function; deletion causes defects in mitochondrial organization but not in growth or translation initiation, can rescue cytokinesis and mitochondrial organization defects of the Dictyostelium cluA- mutant" Verified chr13:291133-294966 291133-294966 99.0% 673.83 519.14 621.66 610.85 284.08 299.36 596.49 616.25 291.72 2.20 2.50 1.21 -1.08 -0.57 Matched[4362]
YMR013C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified ORF SEC59/YML013C" Dubious chr13:296470-296619 296470-296619 99.2% 53.77 60.49 47.05 33.60 26.88 40.32 57.13 40.32 33.60 0.21 0.16 0.14 -0.26 NaN Covered/w/another[4363]
YMR013C SEC59 "Dolichol kinase, catalyzes the terminal step in dolichyl monophosphate (Dol-P) biosynthesis; required for viability and for normal rates of lipid intermediate synthesis and protein N-glycosylation" Verified chr13:295178-296737 295178-296737 99.0% 114.56 123.62 86.08 62.13 97.73 49.84 119.09 74.11 73.78 0.44 0.30 0.31 -0.01 0.47 Matched[4363]
YMR013W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the characterized snoRNA gene snR73" Dubious chr13:298310-298390 298310-298390 99.0% 62.34 24.94 12.47 0.00 37.40 24.94 43.64 6.23 31.17 0.16 0.03 0.13 2.32 -0.18 Covered/w/another[4364]
YMR014W BUD22 Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern Verified chr13:298867-300426 298867-300426 98.3% 225.74 129.18 138.31 103.74 19.57 11.74 177.46 121.02 15.66 0.66 0.49 0.06 -2.95 -2.94 Covered/w/another[4364]
YMR015C ERG5 "C-22 sterol desaturase, a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugs" Verified chr13:300868-302484 300868-302484 98.9% 332.61 572.07 341.37 340.12 135.05 100.03 452.34 340.74 117.54 1.67 1.38 0.49 -1.54 -1.12 Frag>80[4365,4366]
YMR016C SOK2 Nuclear protein that plays a regulatory role in the cyclic AMP (cAMP)-dependent protein kinase (PKA) signal transduction pathway; negatively regulates pseudohyphal differentiation; homologous to several transcription factors Verified chr13:303235-305592 303235-305592 98.6% 124.24 109.63 102.32 79.53 40.41 33.96 116.93 90.93 37.19 0.43 0.37 0.15 -1.29 -0.53 Matched[4367]
YMR017W SPO20 "Meiosis-specific subunit of the t-SNARE complex, required for prospore membrane formation during sporulation; similar to but not functionally redundant with Sec9p; SNAP-25 homolog" Verified chr13:307488-308681 307488-308681 98.4% 4.25 3.40 3.40 1.70 11.91 7.66 3.83 2.55 9.78 0.01 0.01 0.04 1.94 1.56
YMR018W Putative protein of unknown function with similarity to human PEX5Rp (peroxin protein 5 related protein); transcription increases during colony development similar to genes involved in peroxisome biogenesis; YMR018W is not an essential gene Uncharacterized chr13:310207-311751 310207-311751 98.9% 17.67 9.81 11.12 9.81 15.70 11.78 13.74 10.47 13.74 0.05 0.04 0.06 0.39 0.73 Frag<80[4368,4369]
YMR019W STB4 Protein that binds Sin3p in a two-hybrid assay; contains a Zn(II)2Cys6 zinc finger domain characteristic of DNA-binding proteins Verified chr13:312155-315004 312155-315004 98.8% 86.98 96.92 58.22 61.06 51.48 49.70 91.95 59.64 50.59 0.34 0.24 0.21 -0.24 -0.27 Covered/w/another[4370]
YMR020W FMS1 "Polyamine oxidase, converts spermine to spermidine, which is required for the essential hypusination modification of translation factor eIF-5A; also involved in pantothenic acid biosynthesis" Verified chr13:315376-316902 315376-316902 98.7% 107.51 205.72 88.93 88.93 247.53 177.85 156.62 88.93 212.69 0.58 0.36 0.88 1.26 1.03 Covered/w/another[4370]
YMR021C MAC1 Copper-sensing transcription factor involved in regulation of genes required for high affinity copper transport Verified chr13:317164-318417 317164-318417 99.0% 91.82 101.49 87.79 74.91 99.07 72.49 96.65 81.35 85.78 0.36 0.33 0.36 0.08 0.58 Covered/w/another[4370]
YMR022W UBC7 "Ubiquitin conjugating enzyme, involved in the ER-associated protein degradation pathway; requires Cue1p for recruitment to the ER membrane; proposed to be involved in chromatin assembly" Verified chr13:318679-319176 318679-319176 98.7% 427.23 482.16 443.50 435.36 1116.89 677.46 454.69 439.43 897.18 1.68 1.78 3.72 1.03 0.83 Matched[4371]
YMR023C MSS1 "Mitochondrial protein, forms a heterodimer complex with Mto1p that performs the 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs; similar to human GTPBP3" Verified chr13:319436-321016 319436-321016 99.2% 44.64 51.02 44.00 33.80 72.06 39.54 47.83 38.90 55.80 0.18 0.16 0.23 0.52 0.64 Matched[4372]
YMR024W MRPL3 Mitochondrial ribosomal protein of the large subunit Verified chr13:321874-323046 321874-323046 98.8% 239.80 281.21 280.34 259.64 221.69 179.42 260.50 269.99 200.55 0.96 1.10 0.83 -0.43 0.06 Matched[4373]
YMR025W CSI1 "Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in adaptation to pheromone signaling" Verified chr13:323299-324186 323299-324186 99.1% 36.36 55.67 53.40 51.13 104.53 72.72 46.02 52.27 88.62 0.17 0.21 0.37 0.76 0.54 Covered/w/another[4374]
YMR026C PEX12 C3HC4-type RING-finger peroxisomal membrane peroxin required for peroxisome biogenesis and peroxisomal matrix protein import; forms translocation subcomplex with Pex2p and Pex10p; mutations in human homolog cause peroxisomal disorders Verified chr13:324235-325434 324235-325434 99.1% 119.39 109.30 118.55 97.53 86.60 71.47 114.35 108.04 79.04 0.42 0.44 0.33 -0.45 0.04 Covered/w/another[4374]
YMR027W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR027W is not an essential gene Uncharacterized chr13:325876-327288 325876-327288 98.6% 440.62 437.75 460.71 452.10 609.97 457.84 439.18 456.40 533.91 1.62 1.85 2.21 0.23 0.57 Matched[4375]
YMR028W TAP42 Essential protein involved in the TOR signaling pathway; physically associates with the protein phosphatase 2A and the SIT4 protein phosphatase catalytic subunits Verified chr13:327481-328581 327481-328581 98.6% 92.99 111.41 113.25 103.12 164.81 96.68 102.20 108.19 130.75 0.38 0.44 0.54 0.27 0.44 Matched[4376]
YMR029C FAR8 "Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway different from the Far1p-dependent pathway; interacts with Far3p, Far7p, Far9p, Far10p, and Far11p" Verified chr13:328659-330230 328659-330230 99.2% 184.06 243.70 193.04 202.01 393.13 295.65 213.88 197.53 344.39 0.79 0.80 1.43 0.80 0.60 Matched[4377]
YMR030W RSF1 Protein required for respiratory growth; localized to both the nucleus and mitochondrion; mutant displays decreased transcription of specific nuclear and mitochondrial genes whose products are involved in respiratory growth Verified chr13:330792-331922 330792-331922 98.9% 61.68 94.76 66.15 62.57 185.04 164.48 78.22 64.36 174.76 0.29 0.26 0.72 1.44 1.47 Frag>80[4378,4379]
YMR031W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; null mutant displays shortened telomeres; partially overlaps the uncharacterized ORF YMR031C" Dubious chr13:334708-335034 334708-335034 98.6% 21.70 46.50 58.90 49.60 62.00 102.30 34.10 54.25 82.15 0.13 0.22 0.34 0.60 2.17 Overlap[4380]
YMR031C "Protein of unknown function with similarity to Ykl050cp and Uso1p; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies; YMR031C is not an essential gene" Uncharacterized chr13:332211-334742 332211-334742 99.3% 185.76 272.48 305.10 330.55 581.95 513.93 229.12 317.83 547.94 0.85 1.29 2.27 0.79 1.18 Matched[4380]
YMR032W HOF1 "Bud neck-localized, SH3 domain-containing protein required for cytokinesis; regulates actomyosin ring dynamics and septin localization; interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p" Verified chr13:335297-337306 335297-337306 98.5% 97.47 102.53 84.34 81.31 86.36 72.73 100.00 82.83 79.55 0.37 0.34 0.33 -0.06 0.79 Matched[4381]
YMR030W-A Putative protein of unknown function Uncharacterized chr13:337312-337602 337312-337602 99.1% 76.29 93.63 48.55 34.68 58.95 34.68 84.96 41.61 46.81 0.31 0.17 0.19 0.17 NaN Covered/w/another[4381]
YMR033W ARP9 Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation Verified chr13:337787-339276 337787-337816,337903-339276 98.9% 279.49 268.68 272.29 223.30 172.88 106.61 274.09 247.79 139.74 1.01 1.01 0.58 -0.83 -0.90 Matched[4382]
YMR034C "Putative transporter, member of the SLC10 carrier family; identified in a transposon mutagenesis screen as a gene involved in azole resistance; YMR034C is not an essential gene" Uncharacterized chr13:339417-340721 339417-340721 97.6% 11.77 14.13 21.19 10.99 47.88 21.19 12.95 16.09 34.54 0.05 0.07 0.14 1.10 0.45 Matched[4383]
YMR035W IMP2 "Catalytic subunit of the mitochondrial inner membrane peptidase complex, required for maturation of mitochondrial proteins of the intermembrane space; complex contains Imp1p and Imp2p (both catalytic subunits), and Som1p" Verified chr13:341141-341674 341141-341674 98.8% 157.38 157.38 146.01 151.69 269.26 163.07 157.38 148.85 216.16 0.58 0.60 0.90 0.54 0.56 Covered/w/another[4384]
YMR036C MIH1 Protein tyrosine phosphatase involved in cell cycle control; regulates the phosphorylation state of Cdc28p; homolog of S. pombe cdc25 Verified chr13:341855-343519 341855-343519 99.0% 66.10 53.37 53.37 47.91 106.12 60.64 59.73 50.64 83.38 0.22 0.21 0.35 0.72 1.02 Matched[4384]
YMR037C MSN2 "Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression" Verified chr13:344402-346516 344402-346516 98.9% 156.88 153.06 172.67 153.54 116.23 132.49 154.97 163.10 124.36 0.57 0.66 0.52 -0.39 0.56 Matched[4386]
YMR038C CCS1 "Copper chaperone for superoxide dismutase Sod1p, involved in oxidative stress protection; Met-X-Cys-X2-Cys motif within the N-terminal portion is involved in insertion of copper into Sod1p under conditions of copper deprivation" Verified chr13:347510-348259 347510-348259 98.7% 642.77 599.56 637.37 645.47 530.69 418.61 621.17 641.42 474.65 2.29 2.60 1.97 -0.43 0.01 Matched[4388]
YMR039C SUB1 "Transcriptional coactivator, facilitates elongation by influencing enzymes that modify RNAP II, acts in a peroxide resistance pathway involving Rad2p; suppressor of TFIIB mutations" Verified chr13:348643-349521 348643-349521 99.4% 546.11 509.47 486.57 555.26 515.19 411.01 527.79 520.92 463.10 1.95 2.11 1.92 -0.17 -0.05 Matched[4390]
YMR040W YET2 "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; homolog of human BAP31 protein" Verified chr13:350380-350862 350380-350862 98.4% 42.08 73.65 54.71 50.50 130.46 44.19 57.86 52.60 87.32 0.21 0.21 0.36 0.73 0.38 Matched[4392]
YMR041C ARA2 "NAD-dependent arabinose dehydrogenase, involved in biosynthesis of erythroascorbic acid; similar to plant L-galactose dehydrogenase" Verified chr13:350965-351972 350965-351972 99.1% 103.10 84.08 88.08 72.07 373.36 207.20 93.59 80.08 290.28 0.35 0.33 1.20 1.86 1.50 Matched[4393]
YMR042W ARG80 Transcription factor involved in regulation of arginine-responsive genes; acts with Arg81p and Arg82p Verified chr13:352602-353135 352602-353135 98.1% 108.78 99.24 82.06 78.24 106.87 40.08 104.01 80.15 73.47 0.38 0.33 0.30 -0.13 -0.15 Covered/w/another[4394]
YMR043W MCM1 Transcription factor involved in cell-type-specific transcription and pheromone response; plays a central role in the formation of both repressor and activator complexes Verified chr13:353870-354730 353870-354730 94.9% 521.18 446.55 505.28 433.09 533.41 391.50 483.87 469.18 462.46 1.79 1.90 1.92 -0.02 0.29 Covered/w/another[4394]
YMR044W IOC4 "Member of a complex (Isw1b) with Isw1p and Ioc2p that exhibits nucleosome-stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing, contains a PWWP motif" Verified chr13:355383-356810 355383-356810 98.0% 198.55 189.27 187.13 201.41 239.26 160.70 193.91 194.27 199.98 0.72 0.79 0.83 0.04 0.08 Matched[4395]
YMR046W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr13:362701-362829 362701-362829 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.09
YMR047C NUP116 Subunit of the nuclear pore complex (NPC) that is localized to both sides of the pore; contains a repetitive GLFG motif that interacts with mRNA export factor Mex67p and with karyopherin Kap95p; homologous to Nup100p Verified chr13:363363-366704 363363-366704 99.0% 211.88 203.12 197.07 173.50 136.92 166.24 207.50 185.29 151.58 0.77 0.75 0.63 -0.29 0.44 Matched[4397]
YMR048W CSM3 Protein required for accurate chromosome segregation during meiosis Verified chr13:366980-367933 366980-367933 98.4% 80.97 87.36 79.90 77.77 72.44 37.29 84.16 78.84 54.87 0.31 0.32 0.23 -0.52 -0.41 Matched[4398]
YMR049C ERB1 Protein required for maturation of the 25S and 5.8S ribosomal RNAs; constituent of 66S pre-ribosomal particles; homologous to mammalian Bop1 Verified chr13:368093-370516 368093-370516 99.1% 231.85 111.55 161.50 116.97 12.07 6.24 171.70 139.23 9.16 0.63 0.57 0.04 -3.93 -3.24 Matched[4399]
YMR052W FAR3 "Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway different from the Far1p-dependent pathway; interacts with Far7p, Far8p, Far9p, Far10p, and Far11p" Verified chr13:379585-380199 379585-380199 98.6% 117.05 89.02 67.59 89.02 138.48 72.54 103.04 78.31 105.51 0.38 0.32 0.44 0.43 0.58 Covered/w/another[4401]
YMR052C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr13:380068-380433 380068-380433 98.9% 99.47 88.42 74.60 121.57 185.13 129.86 93.94 98.09 157.49 0.35 0.40 0.65 0.68 1.05 Covered/w/another[4401]
YMR053C STB2 Protein that interacts with Sin3p in a two-hybrid assay and is part of a large protein complex with Sin3p and Stb1p Verified chr13:380345-382897 380345-382897 99.3% 33.94 49.73 42.62 50.91 117.21 134.18 41.83 46.77 125.70 0.15 0.19 0.52 1.43 1.31 Matched[4401]
YMR054W STV1 "Subunit a of the vacuolar-ATPase V0 domain, one of two isoforms (Stv1p and Vph1p); Stv1p is located in V-ATPase complexes of the Golgi and endosomes while Vph1p is located in V-ATPase complexes of the vacuole" Verified chr13:383302-385974 383302-385974 98.8% 243.21 187.52 227.68 205.33 236.39 200.02 215.36 216.50 218.21 0.80 0.88 0.90 0.01 0.42 Matched[4402]
YMR055C BUB2 "Mitotic exit network regulator, forms GTPase-activating Bfa1p-Bub2p complex that binds Tem1p and spindle pole bodies, blocks cell cycle progression before anaphase in response to spindle and kinetochore damage" Verified chr13:386100-387020 386100-387020 98.5% 73.89 86.02 52.93 47.42 48.52 56.24 79.95 50.18 52.38 0.30 0.20 0.22 0.06 0.01 Matched[4403]
YMR056C AAC1 "Mitochondrial inner membrane ADP/ATP translocator, exchanges cytosolic ADP for mitochondrially synthesized ATP; phosphorylated; Aac1p is a minor isoform while Pet9p is the major ADP/ATP translocator" Verified chr13:387314-388243 387314-388243 98.6% 66.50 103.56 61.05 55.60 176.60 104.65 85.03 58.32 140.63 0.31 0.24 0.58 1.27 1.09 Frag>80[4404,4405]
YMR057C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF AAC1" Dubious chr13:388358-388729 388358-388729 94.9% 5.67 2.83 2.83 5.67 22.66 14.16 4.25 4.25 18.41 0.02 0.02 0.08 2.12 -0.42 Matched[4405]
YMR058W FET3 "Ferro-O2-oxidoreductase required for high-affinity iron uptake and involved in mediating resistance to copper ion toxicity, belongs to class of integral membrane multicopper oxidases" Verified chr13:388821-390731 388821-390731 98.7% 1118.20 334.40 966.64 593.55 322.21 253.32 726.30 780.09 287.76 2.68 3.17 1.19 -1.44 -0.60 Frag>80[4405,4406,4407]
YMR059W SEN15 "Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p" Verified chr13:391098-391484 391098-391484 98.7% 94.23 78.53 83.76 83.76 60.20 18.32 86.38 83.76 39.26 0.32 0.34 0.16 -1.09 -0.69 Covered/w/another[4408]
YMR060C SAM37 Component of the mitochondrial outer membrane sorting and assembly machinery (SAM) complex; required for the sorting of some proteins to the outer membrane after import by the TOM complex Verified chr13:391531-392514 391531-392514 99.3% 160.68 170.92 154.54 102.35 163.75 73.69 165.80 128.44 118.72 0.61 0.52 0.49 -0.11 -0.43 Matched[4408]
YMR061W RNA14 Cleavage and polyadenylation factor I (CF I) component involved in cleavage and polyadenylation of mRNA 3' ends; bridges interaction between Rna15p and Hrp1p in the CF I complex Verified chr13:392754-394787 392754-394787 98.9% 189.49 178.05 134.78 122.34 129.31 62.66 183.77 128.56 95.99 0.68 0.52 0.40 -0.42 -1.16 Covered/w/another[4409]
YMR062C ECM40 "Mitochondrial ornithine acetyltransferase, catalyzes the fifth step in arginine biosynthesis; also possesses acetylglutamate synthase activity, regenerates acetylglutamate while forming ornithine" Verified chr13:395053-396378 395053-396378 99.1% 174.18 479.19 123.22 172.66 111.05 81.39 326.69 147.94 96.22 1.21 0.60 0.40 -0.62 -0.43 Covered/w/another[4409]
YMR063W RIM9 "Protein of unknown function, involved in the proteolytic activation of Rim101p in response to alkaline pH; has similarity to A. nidulans PalI; putative membrane protein" Verified chr13:397076-397795 397076-397795 99.0% 36.48 44.90 23.85 37.89 16.84 22.45 40.69 30.87 19.64 0.15 0.13 0.08 -0.65 0.45 Matched[4410]
YMR064W AEP1 Protein required for expression of the mitochondrial OLI1 gene encoding subunit 9 of F1-F0 ATP synthase Verified chr13:397902-399458 397902-399458 99.0% 140.17 151.20 138.23 110.32 125.90 115.51 145.69 124.27 120.70 0.54 0.50 0.50 -0.04 0.40 Matched[4411]
YMR065W KAR5 "Protein required for nuclear membrane fusion during karyogamy, localizes to the membrane with a soluble portion in the endoplasmic reticulum lumen, may form a complex with Jem1p and Kar2p; expression of the gene is regulated by pheromone" Verified chr13:399701-401215 399701-401215 98.9% 63.39 103.42 58.72 43.37 55.38 37.37 83.41 51.04 46.37 0.31 0.21 0.19 -0.14 -0.76 Matched[4412]
YMR066W SOV1 Mitochondrial protein of unknown function Verified chr13:401540-404236 401540-404236 98.9% 53.62 66.37 46.12 50.62 62.24 41.99 59.99 48.37 52.12 0.22 0.20 0.22 0.11 0.19 Matched[4413]
YMR067C UBX4 UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p Verified chr13:404322-405572 404322-405572 99.0% 151.80 151.80 137.27 130.00 235.78 171.99 151.80 133.63 203.88 0.56 0.54 0.84 0.61 0.98 Matched[4414]
YMR068W AVO2 "Component of a complex containing the Tor2p kinase and other proteins, which may have a role in regulation of cell growth" Verified chr13:406303-407583 406303-407583 98.4% 34.92 54.76 42.06 43.65 95.24 72.22 44.84 42.86 83.73 0.17 0.17 0.35 0.97 1.27 Covered/w/another[4415]
YMR069W NAT4 "N alpha-acetyl-transferase, involved in acetylation of the N-terminal residues of histones H4 and H2A" Verified chr13:407708-408565 407708-408565 98.1% 23.77 21.39 10.69 5.94 24.95 32.08 22.58 8.32 28.52 0.08 0.03 0.12 1.78 0.80 Covered/w/another[4415]
YMR070W MOT3 "Nuclear transcription factor with two Cys2-His2 zinc fingers; involved in repression of a subset of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth, and repression of ergosterol biosynthetic genes" Verified chr13:409153-410625 409153-410625 97.5% 286.06 240.13 299.29 202.54 333.39 261.01 263.09 250.91 297.20 0.97 1.02 1.23 0.24 0.65 Matched[4416]
YMR071C TVP18 "Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; may interact with ribosomes, based on co-purification experiments" Verified chr13:410761-411264 410761-411264 99.4% 517.18 684.92 581.08 517.18 806.72 533.16 601.05 549.13 669.94 2.22 2.23 2.78 0.29 0.13 Matched[4417]
YMR072W ABF2 "Mitochondrial DNA-binding protein involved in mitochondrial DNA replication and recombination, member of HMG1 DNA-binding protein family; activity may be regulated by protein kinase A phosphorylation" Verified chr13:411568-412119 411568-412119 98.8% 1325.19 1283.03 1325.19 1195.05 1755.92 1024.59 1304.11 1260.12 1390.26 4.81 5.12 5.76 0.14 0.14 Matched[4418]
YMR073C Putative protein of unknown function; proposed to be involved in resistance to carboplatin and cisplatin; shares similarity to a human cytochrome oxidoreductase; null mutant displays increased levels of spontaneous Rad52 foci Uncharacterized chr13:412267-412872 412267-412872 98.9% 193.53 221.90 156.83 175.18 231.91 158.50 207.72 166.01 195.20 0.77 0.67 0.81 0.23 -0.16 Matched[4419]
YMR074C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR074C is not an essential gene Uncharacterized chr13:413035-413472 413035-413472 99.4% 820.14 953.38 787.98 762.71 1203.79 778.79 886.76 775.34 991.29 3.27 3.15 4.11 0.35 0.00 Matched[4420]
YMR075W RCO1 Essential subunit of the histone deacetylase Rpd3S complex; interacts with Eaf3p Verified chr13:413981-416035 413981-416035 99.0% 123.82 112.51 100.23 105.64 113.01 91.88 118.16 102.93 102.44 0.44 0.42 0.42 -0.01 0.28 Covered/w/another[4421]
YMR075C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified ORF RCO1/YMR075W" Dubious chr13:415687-416052 415687-416052 98.7% 215.84 185.40 163.27 143.89 213.08 124.52 200.62 153.58 168.80 0.74 0.62 0.70 0.14 -0.28 Covered/w/another[4421]
YMR076C PDS5 "Protein required for establishment and maintenance of sister chromatid condensation and cohesion, colocalizes with cohesin on chromosomes in an interdependent manner, may function as a protein-protein interaction scaffold" Verified chr13:416195-420028 416195-420028 99.2% 158.31 120.70 129.12 113.87 51.28 49.70 139.51 121.49 50.49 0.51 0.49 0.21 -1.27 -0.47 Frag<80[4422]
YMR077C VPS20 "Myristoylated subunit of ESCRTIII, the endosomal sorting complex required for transport of transmembrane proteins into the multivesicular body pathway to the lysosomal/vacuolar lumen; cytoplasmic protein recruited to endosomal membranes" Verified chr13:421483-422148 421483-422148 99.7% 108.47 100.94 84.36 84.36 191.33 128.05 104.70 84.36 159.69 0.39 0.34 0.66 0.92 0.32 Matched[4424]
YMR078C CTF18 Subunit of a complex with Ctf8p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion; may have overlapping functions with Rad24p in the DNA damage replication checkpoint Verified chr13:422502-424727 422502-424727 99.3% 137.12 110.87 100.47 94.58 55.21 45.71 124.00 97.52 50.46 0.46 0.40 0.21 -0.95 -0.57 Covered/w/another[4425]
YMR079W SEC14 "Phosphatidylinositol/phosphatidylcholine transfer protein involved in coordinate regulation of PtdIns and PtdCho metabolism, products of which are regulators in Golgi to plasma membrane transport; functionally homologous to mammalian PITPs" Verified chr13:424988-426058 424988-424996,425153-426058 98.9% 783.32 701.56 723.66 681.67 365.70 320.40 742.44 702.67 343.05 2.74 2.85 1.42 -1.03 -0.47 Covered/w/another[4425]
YMR080C NAM7 "ATP-dependent RNA helicase of the SFI superfamily, required for nonsense mediated mRNA decay and for efficient translation termination at nonsense codons; involved in telomere maintenance" Verified chr13:426711-429626 426711-429626 99.1% 218.01 214.55 183.06 165.76 103.12 105.55 216.28 174.41 104.33 0.80 0.71 0.43 -0.74 -0.24 Matched[4426]
YMR081C ISF1 "Serine-rich, hydrophilic protein with similarity to Mbr1p; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants; expression is under glucose control; cotranscribed with NAM7 in a cyp1 mutant" Verified chr13:430078-431094 430078-431094 98.6% 37.90 91.76 69.81 76.80 139.63 101.73 64.83 73.30 120.68 0.24 0.30 0.50 0.72 0.92 Matched[4427]
YMR082C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr13:431768-432124 431768-432124 98.7% 11.35 2.84 2.84 0.00 2.84 14.19 7.10 1.42 8.51 0.03 0.01 0.04 2.58 0.58 Frag<80[4428]
YMR083W ADH3 Mitochondrial alcohol dehydrogenase isozyme III; involved in the shuttling of mitochondrial NADH to the cytosol under anaerobic conditions and ethanol production Verified chr13:434787-435914 434787-435914 98.3% 2103.89 2065.13 2016.45 1883.94 1662.20 1418.82 2084.51 1950.20 1540.51 7.69 7.92 6.38 -0.34 -0.06 Matched[4430]
YMR084W Putative protein of unknown function; YMR084W and adjacent ORF YMR085W are merged in related strains Uncharacterized chr13:436627-437415 436627-437415 98.8% 12.83 20.53 10.27 19.25 43.64 50.05 16.68 14.76 46.84 0.06 0.06 0.19 1.67 2.58 Covered/w/another[4432]
YMR085W Putative protein of unknown function; YMR085W and adjacent ORF YMR084W are merged in related strains Uncharacterized chr13:437490-438788 437490-438788 98.7% 27.30 27.30 23.40 20.28 91.26 85.80 27.30 21.84 88.53 0.10 0.09 0.37 2.02 2.01 Covered/w/another[4432]
YMR086W "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; cAMP represses YMR086W expression" Verified chr13:439207-442089 439207-442089 98.6% 142.87 174.89 140.40 149.91 158.35 178.06 158.88 145.15 168.20 0.59 0.59 0.70 0.21 0.63 Matched[4433]
YMR086C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr13:442025-442363 442025-442363 99.2% 127.93 190.41 172.55 113.05 187.43 142.80 159.17 142.80 165.12 0.59 0.58 0.68 0.21 0.48
YMR087W Putative ADP-ribose-1''-monophosphatase that converts ADP-ribose-1''-monophosphate to ADP-ribose; may have a role in tRNA splicing; contains an A1pp domain Verified chr13:442526-443380 442526-443380 98.8% 103.00 99.45 78.14 58.01 113.65 58.01 101.22 68.07 85.83 0.37 0.28 0.36 0.33 0.63 Matched[4434]
YMR088C VBA1 Permease of basic amino acids in the vacuolar membrane Verified chr13:443413-445101 443413-445101 99.0% 193.83 199.81 185.45 145.37 121.44 92.13 196.82 165.41 106.78 0.73 0.67 0.44 -0.63 -0.25 Matched[4435]
YMR089C YTA12 "Component, with Afg3p, of the mitochondrial inner membrane m-AAA protease that mediates degradation of misfolded or unassembled proteins and is also required for correct assembly of mitochondrial enzyme complexes" Verified chr13:445608-448085 445608-448085 99.2% 308.78 271.76 299.83 288.44 255.89 262.40 290.27 294.14 259.15 1.07 1.19 1.07 -0.18 0.07 Matched[4436]
YMR090W "Putative protein of unknown function with similarity to DTDP-glucose 4,6-dehydratases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YMR090W is not an essential gene" Uncharacterized chr13:449244-449927 449244-449927 98.5% 234.46 690.04 293.82 316.08 1621.96 1074.38 462.25 304.95 1348.17 1.71 1.24 5.59 2.14 1.67 Matched[4438]
YMR091C NPL6 "Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Ldb7p, and Htl1p to form a module important for a broad range of RSC functions; involved in nuclear protein import and maintenance of proper telomere length" Verified chr13:450057-451364 450057-451364 99.3% 320.42 301.16 305.79 273.44 274.21 157.90 310.79 289.61 216.05 1.15 1.18 0.90 -0.42 -0.40 Matched[4439]
YMR092C AIP1 "Actin cortical patch component, interacts with the actin depolymerizing factor cofilin; required to restrict cofilin localization to cortical patches; contains WD repeats" Verified chr13:451631-453478 451631-453478 99.0% 377.58 369.93 403.26 388.51 757.89 678.11 373.75 395.88 718.00 1.38 1.61 2.97 0.86 1.21 Frag>80[4440,4441]
YMR093W UTP15 "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" Verified chr13:454014-455555 454014-455555 98.9% 232.76 148.18 160.63 114.74 22.29 5.90 190.47 137.69 14.10 0.70 0.56 0.06 -3.29 -1.67 Matched[4442]
YMR094W CTF13 "Subunit of the CBF3 complex, which binds to the CDE III element of centromeres, bending the DNA upon binding, and may be involved in sister chromatid cohesion during mitosis" Verified chr13:455824-457260 455824-457260 98.8% 34.50 31.69 23.24 15.49 20.42 18.31 33.09 19.36 19.36 0.12 0.08 0.08 0.00 -0.40 Overlap[4442,4443]
YMR095C SNO1 "Protein of unconfirmed function, involved in pyridoxine metabolism; expression is induced during stationary phase; forms a putative glutamine amidotransferase complex with Snz1p, with Sno1p serving as the glutaminase" Verified chr13:457284-457958 457284-457958 99.0% 94.25 97.24 40.39 40.39 40.39 37.40 95.75 40.39 38.90 0.35 0.16 0.16 -0.05 -0.21 Covered/w/another[4443]
YMR096W SNZ1 "Protein involved in vitamin B6 biosynthesis; member of a stationary phase-induced gene family; coregulated with SNO1; interacts with Sno1p and with Yhr198p, perhaps as a multiprotein complex containing other Snz and Sno proteins" Verified chr13:458407-459300 458407-459300 98.4% 156.92 255.85 130.77 90.97 63.68 39.80 206.39 110.87 51.74 0.76 0.45 0.21 -1.10 -0.53 Covered/w/another[4443]
YMR097C MTG1 "Peripheral GTPase of the mitochondrial inner membrane, essential for respiratory competence, likely functions in assembly of the large ribosomal subunit, has homologs in plants and animals" Verified chr13:459423-460526 459423-460526 99.4% 102.08 124.87 113.93 104.82 167.70 97.52 113.47 109.37 132.61 0.42 0.44 0.55 0.28 0.44 Covered/w/another[4443]
YMR098C "Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YMR098C is not an essential gene" Uncharacterized chr13:460770-462608 460770-462608 99.3% 98.04 110.64 106.26 105.71 152.82 108.45 104.34 105.99 130.63 0.39 0.43 0.54 0.30 0.56 Matched[4444]
YMR099C "Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase), likely involved in carbohydrate metabolism; GFP-fusion protein localizes to both the nucleus and cytoplasm and is induced in response to the DNA-damaging agent MMS" Verified chr13:463933-464826 463933-464826 99.1% 775.54 829.73 754.09 742.80 1183.07 941.49 802.63 748.45 1062.28 2.96 3.04 4.40 0.51 0.65 Frag>80[4445,4446,4447]
YMR100W MUB1 "Protein of unknown function, deletion causes multi-budding phenotype; has similarity to Aspergillus nidulans samB gene" Verified chr13:466299-468161 466299-468161 98.8% 114.08 115.71 114.08 82.57 129.29 93.98 114.90 98.33 111.64 0.42 0.40 0.46 0.18 0.12 Matched[4448]
YMR101C SRT1 Cis-prenyltransferase involved in synthesis of long-chain dolichols (19-22 isoprene units; as opposed to Rer2p which synthesizes shorter-chain dolichols); localizes to lipid bodies; transcription is induced during stationary phase Verified chr13:468444-469475 468444-469475 99.2% 11.72 19.53 5.86 4.88 22.46 25.39 15.62 5.37 23.92 0.06 0.02 0.10 2.16 1.03 Frag<80[4449]
YMR102C Protein of unknown function; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; mutant shows increased resistance to azoles; YMR102C is not an essential gene Uncharacterized chr13:469847-472351 469847-472351 99.1% 113.22 108.38 102.34 80.18 143.84 154.32 110.80 91.26 149.08 0.41 0.37 0.62 0.71 1.28 Covered/w/another[4450]
YMR103C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr13:472901-473263 472901-473263 98.3% 128.87 123.26 162.48 154.08 619.12 341.78 126.07 158.28 480.45 0.47 0.64 1.99 1.60 1.28 Covered/w/another[4450]
YMR104C YPK2 Protein kinase with similarityto serine/threonine protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; homolog of mammalian kinase SGK Verified chr13:473419-475452 473419-475452 99.0% 51.16 61.09 75.99 82.45 170.36 153.47 56.12 79.22 161.91 0.21 0.32 0.67 1.03 1.50 Covered/w/another[4450]
YMR105C PGM2 "Phosphoglucomutase, catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism; functions as the acceptor for a Glc-phosphotransferase" Verified chr13:475896-477605 475896-477605 98.5% 306.95 1268.16 991.49 1157.73 8849.20 6213.14 787.55 1074.61 7531.17 2.91 4.36 31.20 2.81 2.34 Frag>80[4451,4452]
YMR105W-A Putative protein of unknown function Uncharacterized chr13:478063-478257 478063-478257 98.7% 36.37 46.76 57.16 41.57 31.18 5.20 41.57 49.36 18.19 0.15 0.20 0.08 -1.44 NaN Covered/w/another[4453]
YMR106C YKU80 "Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair" Verified chr13:478300-480189 478300-480189 99.1% 53.93 43.79 48.59 43.25 42.72 37.38 48.86 45.92 40.05 0.18 0.19 0.17 -0.20 0.07 Matched[4453]
YMR107W SPG4 Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources Verified chr13:483013-483360 483013-483360 98.2% 0.00 11.71 8.78 5.86 313.25 143.45 5.86 7.32 228.35 0.02 0.03 0.95 4.96 4.17 Matched[4457]
YMR108W ILV2 "Acetolactate synthase, catalyses the first common step in isoleucine and valine biosynthesis and is the target of several classes of inhibitors, localizes to the mitochondria; expression of the gene is under general amino acid control" Verified chr13:484083-486146 484083-486146 98.7% 629.95 647.14 533.72 437.97 203.76 145.34 638.54 485.84 174.55 2.36 1.97 0.72 -1.48 -0.99 Matched[4458]
YMR109W MYO5 "One of two type I myosins; contains proline-rich tail homology 2 (TH2) and SH3 domains; MYO5 deletion has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization" Verified chr13:486586-490245 486586-490245 98.4% 224.80 241.73 224.25 237.29 189.00 214.53 233.27 230.77 201.77 0.86 0.94 0.84 -0.19 0.42 Matched[4459]
YMR110C HFD1 "Putative fatty aldehyde dehydrogenase, located in the mitochondrial outer membrane and also in lipid particles; has similarity to human fatty aldehyde dehydrogenase (FALDH) which is implicated in Sjogren-Larsson syndrome" Verified chr13:490393-491991 490393-491991 99.1% 209.45 276.96 315.44 331.21 959.57 683.88 243.20 323.33 821.72 0.90 1.31 3.40 1.35 1.29 Frag>80[4460,4461,4462]
YMR111C Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YMR111C is not an essential gene Uncharacterized chr13:492403-493791 492403-493791 99.1% 47.23 61.03 45.78 45.78 105.36 66.12 54.13 45.78 85.74 0.20 0.19 0.36 0.91 1.24 Frag>80[4462,4463,4464]
YMR112C MED11 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential protein Verified chr13:494099-494494 494099-494494 99.2% 190.86 129.78 152.69 157.78 236.67 173.05 160.32 155.23 204.86 0.59 0.63 0.85 0.40 0.36 Matched[4464]
YMR113W FOL3 "Dihydrofolate synthetase, involved in folic acid biosynthesis; catalyzes the conversion of dihydropteroate to dihydrofolate in folate coenzyme biosynthesis" Verified chr13:494998-496281 494998-496281 98.7% 128.59 113.60 106.50 89.93 112.81 85.99 121.10 98.22 99.40 0.45 0.40 0.41 0.02 0.16 Matched[4465]
YMR114C "Protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR114C is not an essential gene" Verified chr13:496342-497448 496342-497448 99.2% 99.25 100.16 88.32 80.13 249.49 158.43 99.70 84.22 203.96 0.37 0.34 0.85 1.28 0.82 Matched[4466]
YMR115W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr13:497703-499208 497703-499208 98.6% 115.20 100.38 114.53 107.12 206.82 148.21 107.79 110.82 177.52 0.40 0.45 0.74 0.68 -0.04 Matched[4467]
YMR116C ASC1 G-beta protein for Gpa2p; involved in translation regulation; required for repression of Gcn4p activity in the absence of amino-acid starvation; core component of the ribosome; ortholog of mammalian RACK1 Verified chr13:499455-500687 499455-499877,500151-500687 98.6% 12581.09 9254.09 10582.14 9029.05 3273.11 3325.94 10917.59 9805.60 3299.52 40.30 39.80 13.67 -1.57 -1.96 Frag>80[4468,4469,4470]
YMR117C SPC24 "Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering" Verified chr13:501249-501890 501249-501890 99.5% 53.21 51.65 43.82 57.91 43.82 39.13 52.43 50.86 41.47 0.19 0.21 0.17 -0.29 0.09 Matched[4471]
YMR118C Protein of unknown function with similarity to succinate dehydrogenase cytochrome b subunit; YMR118C is not an essential gene Uncharacterized chr13:502143-502733 502143-502733 98.8% 61.64 49.65 32.53 25.68 106.15 46.23 55.64 29.11 76.19 0.21 0.12 0.32 1.39 2.09 Matched[4472]
YMR119W ASI1 Putative integral membrane E3 ubiquitin ligase; acts with Asi2p and Asi3p to ensure the fidelity of SPS-sensor signalling by maintaining the dormant repressed state of gene expression in the absence of inducing signals Verified chr13:505332-507206 505332-507206 99.1% 154.43 193.71 171.11 163.58 235.15 196.40 174.07 167.35 215.78 0.64 0.68 0.89 0.37 0.69 Matched[4473]
YMR119W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr13:506995-507369 506995-507369 99.3% 389.57 376.13 343.89 284.79 354.64 228.37 382.85 314.34 291.50 1.41 1.28 1.21 -0.11 0.41 Covered/w/another[4473]
YMR120C ADE17 "Enzyme of 'de novo' purine biosynthesis containing both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities, isozyme of Ade16p; ade16 ade17 mutants require adenine and histidine" Verified chr13:507501-509279 507501-509279 98.9% 4086.92 2784.26 4086.35 3210.91 405.06 121.57 3435.59 3648.63 263.31 12.68 14.81 1.09 -3.79 -3.93 Frag>80[4474,4475,4476]
YMR121C RPL15B "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl15Ap and has similarity to rat L15 ribosomal protein; binds to 5.8 S rRNA" Verified chr13:509733-510347 509733-510347 60.8% 307.73 339.84 412.09 283.64 449.55 238.15 323.78 347.86 343.85 1.20 1.41 1.42 -0.02 -0.19 Frag>80[4476,4477]
YMR122C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr13:510700-511074 510700-511074 98.5% 32.47 35.18 32.47 32.47 27.06 32.47 33.83 32.47 29.77 0.12 0.13 0.12 -0.13 -0.66 Matched[4478]
YMR122W-A Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and endoplasmic reticulum Uncharacterized chr13:511314-511568 511314-511568 99.2% 3594.66 4286.70 3780.52 2807.71 5587.74 3725.16 3940.68 3294.12 4656.45 14.55 13.37 19.29 0.50 -0.35 Matched[4479]
YMR123W PKR1 "V-ATPase assembly factor, functions with other V-ATPase assembly factors in the ER to efficiently assemble the V-ATPase membrane sector (V0); overproduction confers resistance to Pichia farinosa killer toxin" Verified chr13:513592-513960 513592-513960 98.6% 390.38 324.40 357.39 299.66 203.44 148.45 357.39 328.52 175.95 1.32 1.33 0.73 -0.90 -0.75 Matched[4481]
YMR124W "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; interacts with Crm1p in two-hybrid assay; YMR124W is not an essential gene" Uncharacterized chr13:514455-517286 514455-517286 98.7% 145.20 133.04 127.67 129.82 153.42 182.75 139.12 128.75 168.08 0.51 0.52 0.70 0.38 0.74 Covered/w/another[4482]
YMR125W STO1 "Large subunit of the nuclear mRNA cap-binding protein complex, interacts with Npl3p to carry nuclear poly(A)+ mRNA to cytoplasm; also involved in nuclear mRNA degradation and telomere maintenance; orthologous to mammalian CBP80" Verified chr13:517538-520445 517538-517562,517885-520445 99.0% 335.78 242.85 295.17 277.99 161.64 146.02 289.32 286.58 153.83 1.07 1.16 0.64 -0.90 -0.36 Covered/w/another[4482]
YMR126C DLT1 "Protein of unknown function, mutant sensitive to 6-azauracil (6AU) and mycophenolic acid (MPA)" Uncharacterized chr13:520760-521788 520760-521788 99.1% 108.81 130.38 82.35 90.19 94.11 64.70 119.60 86.27 79.41 0.44 0.35 0.33 -0.12 -0.35 Matched[4483]
YMR127C SAS2 "Histone acetyltransferase (HAT) catalytic subunit of the SAS complex (Sas2p-Sas4p-Sas5p), which acetylates free histones and nucleosomes and regulates transcriptional silencing; member of the MYSTacetyltransferase family" Verified chr13:522328-523344 522328-523344 99.0% 114.19 104.26 80.43 73.48 46.67 18.87 109.23 76.95 32.77 0.40 0.31 0.14 -1.23 -2.39 Matched[4484]
YMR128W ECM16 "Essential DEAH-box ATP-dependent RNA helicase specific to the U3 snoRNP, predominantly nucleolar in distribution, required for 18S rRNA synthesis" Verified chr13:523695-527498 523695-527498 98.5% 179.14 83.83 107.33 81.43 11.75 10.68 131.49 94.38 11.21 0.49 0.38 0.05 -3.07 -1.53 Matched[4485]
YMR129W POM152 Nuclear pore membrane glycoprotein; may be involved in duplication of nuclear pores and nuclear pore complexes during S-phase; Verified chr13:527803-531816 527803-531816 99.0% 139.41 116.26 107.70 96.88 50.08 39.00 127.83 102.29 44.54 0.47 0.42 0.18 -1.20 -0.45 Covered/w/another[4486]
YMR130W Putative protein of unknown function; YMR130W is not an essential gene Uncharacterized chr13:532118-533026 532118-533026 99.0% 221.22 200.10 205.66 184.54 211.22 105.61 210.66 195.10 158.41 0.78 0.79 0.66 -0.30 -0.44 Covered/w/another[4486]
YMR131C RRB1 Essential nuclear protein involved in early steps of ribosome biogenesis; physically interacts with the ribosomal protein Rpl3p Verified chr13:533162-534697 533162-534697 99.1% 480.99 260.86 330.51 243.12 28.91 6.57 370.92 286.82 17.74 1.37 1.16 0.07 -4.01 -3.33 Covered/w/another[4486]
YMR132C JLP2 "Protein of unknown function, contains sequence that closely resembles a J domain (typified by the E. coli DnaJ protein)" Uncharacterized chr13:534943-535569 534943-535569 99.6% 65.67 43.24 43.24 49.65 56.06 24.02 54.45 46.45 40.04 0.20 0.19 0.17 -0.21 -0.25 Covered/w/another[4486]
YMR133W REC114 Protein involved in early stages of meiotic recombination; possibly involved in the coordination of recombination and meiotic division; mutations lead to premature initiation of the first meiotic division Verified chr13:536206-537608 536206-537447,537564-537608 98.8% 29.87 38.52 38.52 35.37 182.37 138.35 34.19 36.94 160.36 0.13 0.15 0.66 2.12 2.29 Covered/w/another[4487]
YMR134W Protein that binds to and regulates Erg25p; localized to the ER; null mutant is viable in a respiratory defective background; synthetic lethal with mmt1 and mmt2 mutations; highly conserved in ascomycetes Uncharacterized chr13:537837-538550 537837-538550 98.6% 168.95 177.47 157.60 122.10 235.68 166.11 173.21 139.85 200.90 0.64 0.57 0.83 0.52 0.28 Covered/w/another[4487]
YMR135W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr13:539910-540443 539910-540443 98.5% 24.71 55.13 34.22 38.02 87.45 39.92 39.92 36.12 63.68 0.15 0.15 0.26 0.82 0.62 Overlap[4487]
YMR135C GID8 "Protein of unknown function, involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains LisH and CTLH domains, like Vid30p; dosage-dependent regulator of START" Verified chr13:538688-540055 538688-540055 99.0% 179.40 211.15 210.41 172.76 364.71 249.54 195.28 191.58 307.12 0.72 0.78 1.27 0.68 0.67 Covered/w/another[4487]
YMR136W GAT2 Protein containing GATA family zinc finger motifs; similar to Gln3p and Dal80p; expression repressed by leucine Verified chr13:541198-542880 541198-542880 99.2% 121.63 210.31 122.23 136.01 289.40 284.01 165.97 129.12 286.71 0.61 0.52 1.19 1.15 1.33 Matched[4488]
YMR137C PSO2 Required for a post-incision step in the repair of DNA single and double-strand breaks that result from interstrand crosslinks produced by a variety of mono- and bi-functional psoralen derivatives; induced by UV-irradiation Verified chr13:542977-544962 542977-544962 99.3% 50.19 57.28 41.06 39.54 81.11 59.82 53.73 40.30 70.46 0.20 0.16 0.29 0.81 1.12 Matched[4489]
YMR138W CIN4 GTP-binding protein involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl Verified chr13:545154-545729 545154-545729 98.4% 47.65 61.77 67.06 56.47 30.00 22.94 54.71 61.77 26.47 0.20 0.25 0.11 -1.22 -1.59 Matched[4490]
YMR139W RIM11 Protein kinase required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta Verified chr13:546124-547236 546124-547236 99.0% 171.56 245.09 254.17 271.42 624.53 474.75 208.33 262.79 549.64 0.77 1.07 2.28 1.06 1.36 Matched[4491]
YMR140W SIP5 Protein of unknown function; interacts with both the Reg1p/Glc7p phosphatase and the Snf1p kinase Verified chr13:547713-549182 547713-549182 98.6% 111.80 105.59 93.17 109.73 203.59 207.05 108.70 101.45 205.32 0.40 0.41 0.85 1.02 1.62 Matched[4492]
YMR141C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr13:549735-550043 549735-550043 99.1% 124.12 130.65 143.71 117.58 336.42 182.91 127.38 130.65 259.66 0.47 0.53 1.08 0.99 0.01 Covered/w/another[4492]
YMR141W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene RPL13B/YMR142C" Dubious chr13:550910-551134 550910-551134 99.5% 40.21 22.34 40.21 8.94 0.00 0.00 31.27 24.57 0.00 0.12 0.10 0.00 -Inf NaN Covered/w/another[4493]
YMR142C RPL13B "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl13Ap; not essential for viability; has similarity to rat L13 ribosomal protein" Verified chr13:550205-551206 550205-550800,551203-551206 66.3% 9485.92 7736.99 8134.02 6960.53 1862.00 1625.80 8611.45 7547.27 1743.90 31.79 30.64 7.23 -2.11 -2.47 Matched[4493]
YMR143W RPS16A Protein component of the small (40S) ribosomal subunit; identical to Rps16Bp and has similarity to E. coli S9 and rat S16 ribosomal proteins Verified chr13:551927-552902 551927-551950,552495-552902 74.0% 7112.39 5597.91 5929.60 5091.00 2027.64 1395.57 6355.15 5510.30 1711.60 23.46 22.37 7.09 -1.69 -2.84 Matched[4494]
YMR144W Putative protein of unknown function; localized to the nucleus; YMR144W is not an essential gene Uncharacterized chr13:553361-554389 553361-554389 98.7% 68.95 72.89 71.91 80.77 71.91 37.43 70.92 76.34 54.67 0.26 0.31 0.23 -0.48 -0.54 Matched[4495]
YMR145C NDE1 "Mitochondrial external NADH dehydrogenase, a type II NAD(P)H:quinone oxidoreductase that catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p provide cytosolic NADH to the mitochondrial respiratory chain" Verified chr13:554792-556474 554792-556474 99.0% 449.64 152.48 505.47 554.09 610.52 368.59 301.06 529.78 489.56 1.11 2.15 2.03 -0.11 0.07 Matched[4496]
YMR146C TIF34 "Subunit of the core complex of translation initiation factor 3(eIF3), which is essential for translation" Verified chr13:557480-558523 557480-558523 98.9% 1318.81 860.81 1146.45 918.91 305.98 291.45 1089.81 1032.68 298.72 4.02 4.19 1.24 -1.79 -1.35 Matched[4498]
YMR147W Putative protein of unknown function Uncharacterized chr13:559198-559869 559198-559869 98.8% 63.27 81.35 43.69 49.71 40.68 43.69 72.31 46.70 42.18 0.27 0.19 0.17 -0.15 0.18 Matched[4499]
YMR148W Putative protein of unknown function; predicted to contain a transmembrane domain; YMR148W is not an essential gene Uncharacterized chr13:560365-560811 560365-560811 99.1% 212.17 248.28 259.57 239.26 374.68 277.63 230.23 249.41 326.15 0.85 1.01 1.35 0.39 0.39 Frag<80[4500]
YMR149W SWP1 "Delta subunit of the oligosaccharyl transferase glycoprotein complex, which is required for N-linked glycosylation of proteins in the endoplasmic reticulum" Verified chr13:560995-561855 560995-561855 99.0% 784.60 825.65 816.26 767.01 659.11 548.87 805.12 791.63 603.99 2.97 3.21 2.50 -0.39 -0.34 Matched[4501]
YMR151W YIM2 "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 5% of ORF overlaps the verified gene IMP1" Dubious chr13:562505-562942 562505-562942 99.1% 43.75 46.06 36.85 29.94 71.39 36.85 44.91 33.39 54.12 0.17 0.14 0.22 0.70 -0.43 Matched[4503]
YMR150C IMP1 "Catalytic subunit of the mitochondrial inner membrane peptidase complex, required for maturation of mitochondrial proteins of the intermembrane space; complex contains Imp1p and Imp2p (both catalytic subunits), and Som1p" Verified chr13:561955-562527 561955-562527 99.2% 219.88 270.89 265.61 255.06 420.40 293.76 245.38 260.33 357.08 0.91 1.06 1.48 0.46 -0.22 Matched[4502]
YMR152W YIM1 "Protein of unknown function; null mutant displays sensitivity to DNA damaging agents; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr13:563095-564192 563095-564192 98.9% 231.17 284.58 303.00 310.37 717.45 596.80 257.88 306.69 657.12 0.95 1.24 2.72 1.10 1.27 Matched[4504]
YMR153W NUP53 "Subunit of the nuclear pore complex (NPC), interacts with karyopherin Kap121p or with Nup170p via overlapping regions of Nup53p, involved in activation of the spindle checkpoint mediated by the Mad1p-Mad2p complex" Verified chr13:564434-565861 564434-565861 98.7% 145.51 168.22 127.76 119.24 142.67 109.31 156.86 123.50 125.99 0.58 0.50 0.52 0.03 -0.18 Matched[4505]
YMR153C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene NUP53" Dubious chr13:565573-565908 565573-565908 98.4% 190.48 241.87 178.38 139.08 229.78 151.17 216.18 158.73 190.48 0.80 0.64 0.79 0.26 1.50 Covered/w/another[4505]
YMR154C RIM13 Calpain-like cysteine protease involved in proteolytic activation of Rim101p in response to alkaline pH; has similarity to A. nidulans palB Verified chr13:565998-568181 565998-568181 99.1% 33.27 39.74 23.57 25.42 43.90 50.83 36.51 24.49 47.37 0.13 0.10 0.20 0.95 0.82 Matched[4506]
YMR155W Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen Uncharacterized chr13:568550-570193 568550-570193 98.9% 76.85 109.43 97.75 89.15 107.59 68.86 93.14 93.45 88.22 0.34 0.38 0.37 -0.08 0.09 Matched[4507]
YMR156C TPP1 "DNA 3'-phosphatase that functions in repair of endogenous damage of double-stranded DNA, activity is specific for removal of 3' phosphates at strand breaks; has similarity to the l-2-haloacid dehalogenase superfamily" Verified chr13:570299-571015 570299-571015 99.2% 57.67 53.45 67.51 54.86 118.15 53.45 55.56 61.19 85.80 0.21 0.25 0.36 0.49 0.65 Matched[4508]
YMR157C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr13:571276-572043 571276-572043 99.2% 185.14 177.26 182.51 151.00 246.85 143.12 181.20 166.76 194.99 0.67 0.68 0.81 0.23 0.07 Matched[4509]
YMR158W MRPS8 Mitochondrial ribosomal protein of the small subunit Verified chr13:572247-572714 572247-572714 98.9% 315.45 272.24 267.92 300.32 516.38 300.32 293.84 284.12 408.35 1.08 1.15 1.69 0.52 -0.01 Matched[4510]
YMR158C-A "Putative protein of unknown function, may contain a lipid attachment site; YMR158C-A is not an essential gene" Uncharacterized chr13:573193-573330 573193-573330 60.8% 119.23 71.54 35.77 47.69 309.99 83.46 95.38 41.73 196.72 0.35 0.17 0.82 2.24 NaN Covered/w/another[4511]
YMR158W-B "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene ATG16/YMR159C" Dubious chr13:574470-574790 574470-574790 99.5% 37.56 65.73 50.08 25.04 115.81 65.73 51.64 37.56 90.77 0.19 0.15 0.38 1.27 NaN Covered/w/another[4511]
YMR159C ATG16 Protein that interacts with the Atg12p-Atg5p conjugate during formation of the pre-autophagosomal structure; essential for autophagy Verified chr13:574475-574927 574475-574927 99.5% 28.83 46.58 44.36 17.74 106.46 59.88 37.70 31.05 83.17 0.14 0.13 0.34 1.42 1.07 Covered/w/another[4511]
YMR160W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the membrane of the vacuole; mutant has enhanced sensitivity to overexpression of mutant huntingtin; YMR160W is not an essential gene Uncharacterized chr13:575065-577515 575065-577515 99.0% 54.83 77.10 64.32 66.79 122.04 98.95 65.97 65.55 110.49 0.24 0.27 0.46 0.75 1.11 Matched[4512]
YMR161W HLJ1 "Co-chaperone for Hsp40p, anchored in the ER membrane; with its homolog Hdj1p promotes ER-associated protein degradation (ERAD) of integral membrane substrates; similar to E. coli DnaJ" Verified chr13:577717-578391 577717-578391 98.5% 240.62 233.10 257.16 213.55 551.91 391.00 236.86 235.35 471.46 0.87 0.96 1.95 1.00 0.73 Matched[4513]
YMR162C DNF3 Aminophospholipid translocase (flippase) that maintains membrane lipid asymmetry in post-Golgi secretory vessicles; localizes to the trans-Golgi network; likely involved in protein transport; type 4 P-type ATPase Verified chr13:578950-583920 578950-583920 99.2% 71.79 80.11 73.01 64.90 53.95 58.00 75.95 68.95 55.97 0.28 0.28 0.23 -0.30 0.22 Matched[4514]
YMR163C INP2 Peroxisome-specific receptor important for peroxisome inheritance; co-fractionates with peroxisome membranes and co-localizes with peroxisomes in vivo; physically interacts with the myosin V motor Myo2p; INP2 is not an essential gene Verified chr13:584270-586387 584270-586387 99.2% 71.90 63.81 70.47 63.81 65.24 47.14 67.85 67.14 56.19 0.25 0.27 0.23 -0.26 0.09 Matched[4515]
YMR164C MSS11 Transcription factor involved in regulation of invasive growth and starch degradation; controls the activation of MUC1 and STA2 in response to nutritional signals Verified chr13:587273-589549 587273-589549 92.5% 93.03 86.86 104.42 92.08 102.52 93.03 89.94 98.25 97.77 0.33 0.40 0.41 -0.01 0.64 Frag>80[4516,4517]
YMR165C PAH1 "Mg2+-dependent phosphatidate (PA) phosphatase, catalyzes the dephosphorylation of PA to yield diacylglycerol and Pi, responsible for de novo lipid synthesis; homologous to mammalian lipin 1" Verified chr13:590039-592627 590039-592627 99.1% 61.57 91.57 62.74 60.40 151.58 136.38 76.57 61.57 143.98 0.28 0.25 0.60 1.23 1.62 Matched[4518]
YMR166C Predicted transporter of the mitochondrial inner membrane; has similarity to human mitochondrial ATP-Mg/Pi carriers; YMR166C is not an essential gene Uncharacterized chr13:593366-594472 593366-594472 98.8% 68.58 64.01 68.58 63.10 109.74 105.16 66.30 65.84 107.45 0.24 0.27 0.45 0.71 1.14 Matched[4519]
YMR167W MLH1 Protein required for mismatch repair in mitosis and meiosis as well as crossing over during meiosis; forms a complex with Pms1p and Msh2p-Msh3p during mismatch repair; human homolog is associated with hereditary non-polyposis colon cancer Verified chr13:594885-597194 594885-597194 98.7% 56.15 53.95 45.62 35.09 59.66 42.55 55.05 40.36 51.10 0.20 0.16 0.21 0.34 0.30 Frag>80[4520]
YMR168C CEP3 "Essential kinetochore protein, component of the CBF3 complex that binds the CDEIII region of the centromere; contains an N-terminal Zn2Cys6 type zinc finger domain, a C-terminal acidic domain, and a putative coiled coil dimerization domain" Verified chr13:597331-599157 597331-599157 99.2% 86.65 86.65 56.30 51.88 52.98 45.81 86.65 54.09 49.40 0.32 0.22 0.20 -0.13 0.40 Matched[4521]
YMR169C ALD3 "Cytoplasmic aldehyde dehydrogenase, involved in beta-alanine synthesis; uses NAD+ as the preferred coenzyme; very similar to Ald2p; expression is induced by stress and repressed by glucose" Verified chr13:599351-600871 599351-600871 38.7% 25.45 57.69 39.03 35.63 4649.32 4031.67 41.57 37.33 4340.50 0.15 0.15 17.98 6.86 4.29 Frag<80[4522,4523,4524]
YMR170C ALD2 "Cytoplasmic aldehyde dehydrogenase, involved in ethanol oxidation and beta-alanine biosynthesis; uses NAD+ as the preferred coenzyme; expression is stress induced and glucose repressed; very similar to Ald3p" Verified chr13:601561-603081 601561-603081 38.9% 81.10 77.72 81.10 74.34 386.91 277.09 79.41 77.72 332.00 0.29 0.32 1.38 2.09 2.02 Frag<80[4524,4525,4526,4527]
YMR171C Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to endosomes; mRNA is targeted to the bud via the mRNA transport system involving She2p: YMR171C is not an essential gene Uncharacterized chr13:603867-605519 603867-605519 99.1% 150.83 171.59 164.27 134.34 192.36 131.90 161.21 149.31 162.13 0.60 0.61 0.67 0.12 0.49 Matched[4528]
YMR172W HOT1 Transcription factor required for the transient induction of glycerol biosynthetic genes GPD1 and GPP2 in response to high osmolarity; targets Hog1p to osmostress responsive promoters; has similarity to Msn1p and Gcr1p Verified chr13:605980-608139 605980-608139 98.6% 92.97 92.50 79.82 74.19 51.65 41.32 92.74 77.01 46.49 0.34 0.31 0.19 -0.73 -0.24 Frag>80[4529]
YMR172C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr13:607827-608210 607827-608210 98.0% 116.92 114.26 106.29 98.32 111.60 77.06 115.59 102.30 94.33 0.43 0.42 0.39 -0.12 0.05 Covered/w/another[4529]
YMR173W DDR48 "DNA damage-responsive protein, expression is increased in response to heat-shock stress or treatments that produce DNA lesions; contains multiple repeats of the amino acid sequence NNNDSYGS" Verified chr13:608688-609980 608688-609980 45.4% 1380.58 1716.36 1588.52 1375.47 4157.09 3828.14 1548.47 1482.00 3992.61 5.72 6.02 16.54 1.43 1.33 Frag>80[4530,4531,4532,4533]
YMR173W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene DDR48/YML173W" Dubious chr13:608896-610080 608896-610080 40.5% 1486.08 1810.77 1715.03 1498.57 4901.57 4021.16 1648.43 1606.80 4461.37 6.09 6.52 18.48 1.47 1.57 Frag>80[4530,4531,4532,4533]
YMR174C PAI3 "Cytoplasmic proteinase A (Pep4p) inhibitor, dependent on Pbs2p and Hog1p protein kinases for osmotic induction; intrinsically unstructured, N-terminal half becomes ordered in the active site of proteinase A upon contact" Verified chr13:610158-610364 610158-610364 99.7% 53.30 169.59 58.15 48.46 1274.38 1109.63 111.45 53.30 1192.00 0.41 0.22 4.94 4.48 2.20 Matched[4533]
YMR175W SIP18 Protein of unknown function whose expression is induced by osmotic stress Verified chr13:611015-611254 611015-611254 98.0% 17.01 29.77 12.76 17.01 569.81 318.92 23.39 14.88 444.37 0.09 0.06 1.84 4.90 3.26 Matched[4535]
YMR175W-A Putative protein of unknown function Uncharacterized chr13:611313-611507 611313-611507 99.4% 0.00 10.31 5.16 10.31 51.57 25.78 5.16 7.74 38.68 0.02 0.03 0.16 2.32 NaN Matched[4535]
YMR176W ECM5 "Non-essential protein of unknown function, contains ATP/GTP-binding site motif A; null mutant exhibits cellular volume up to four times greater than wild-type, also large drooping buds with elongated necks" Verified chr13:611739-615974 611739-615974 98.9% 74.97 73.77 53.24 42.26 46.56 41.06 74.37 47.75 43.81 0.27 0.19 0.18 -0.12 0.33 Covered/w/another[4536]
YMR177W MMT1 Putative metal transporter involved in mitochondrial iron accumulation; closely related to Mmt2p Verified chr13:616565-618097 616565-618097 98.8% 122.18 110.96 84.54 68.03 50.85 30.38 116.57 76.28 40.62 0.43 0.31 0.17 -0.91 -0.89 Covered/w/another[4536]
YMR178W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus and is induced in response to the DNA-damaging agent MMS; YMR178W is not an essential gene Uncharacterized chr13:618478-619302 618478-619302 98.8% 333.83 501.97 370.65 348.56 472.51 282.28 417.90 359.60 377.40 1.54 1.46 1.56 0.07 -0.64 Matched[4537]
YMR179W SPT21 "Protein required for normal transcription at several loci including HTA2-HTB2 and HHF2-HHT2, but not required at the other histone loci; functionally related to Spt10p; involved in telomere maintenance" Verified chr13:619857-622133 619857-622133 98.8% 94.72 86.72 70.71 68.04 52.92 31.13 90.72 69.37 42.02 0.33 0.28 0.17 -0.72 -0.14 Covered/w/another[4538]
YMR180C CTL1 "RNA 5'-triphosphatase, localizes to both the nucleus and cytoplasm" Verified chr13:622250-623212 622250-623212 99.0% 114.35 125.89 101.76 77.63 178.35 87.07 120.12 89.70 132.71 0.44 0.36 0.55 0.57 1.01 Covered/w/another[4538]
YMR181C Protein of unknown function; mRNA transcribed as part of a bicistronic transcript with a predicted transcriptional repressor RGM1/YMR182C; mRNA is destroyed by nonsense-mediated decay (NMD); YMR181C is not an essential gene Uncharacterized chr13:623615-624079 623615-624079 98.6% 337.97 436.09 270.37 250.75 843.83 595.26 387.03 260.56 719.54 1.43 1.06 2.98 1.47 1.66 Matched[4540]
YMR182C RGM1 Putative transcriptional repressor with proline-rich zinc fingers; overproduction impairs cell growth Verified chr13:624531-625166 624531-625166 98.4% 179.02 218.98 126.27 103.90 437.96 393.21 199.00 115.08 415.58 0.73 0.47 1.72 1.85 0.13 Matched[4541]
YMR182W-A Putative protein of unknown function Uncharacterized chr13:625810-625896 625810-625896 99.3% 11.58 23.15 34.73 34.73 370.48 173.66 17.37 34.73 272.07 0.06 0.14 1.13 2.97 NaN Matched[4542]
YMR183C SSO2 Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane; syntaxin homolog that is functionally redundant with Sso1p Verified chr13:626920-627807 626920-627807 99.2% 639.23 653.99 646.04 619.93 518.88 449.62 646.61 632.98 484.25 2.39 2.57 2.01 -0.39 0.32 Matched[4544]
YMR184W ADD37 Protein of unknown function involved in ER-associated protein degradation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; YMR184W is not an essential gene Verified chr13:628188-628784 628188-628784 98.7% 198.47 178.12 232.40 174.72 610.69 329.09 188.30 203.56 469.89 0.70 0.83 1.95 1.21 1.10 Frag>80[4545,4546]
YMR185W Putative protein of unknown function; essential gene required for viability Uncharacterized chr13:629024-631969 629024-631969 99.0% 81.94 52.11 31.20 31.54 9.60 6.51 67.03 31.37 8.06 0.25 0.13 0.03 -1.96 -2.54 Matched[4547]
YMR186W HSC82 "Cytoplasmic chaperone of the Hsp90 family, redundant in function and nearly identical with Hsp82p, and together they are essential; expressed constitutively at 10-fold higher basal levels that HSP82 and induced 2-3 fold by heat shock" Verified chr13:632354-634471 632354-634471 60.5% 4763.01 2995.32 4194.85 4745.84 23523.93 20292.92 3879.16 4470.34 21908.43 14.32 18.15 90.77 2.29 1.53 Matched[4548]
YMR187C Putative protein of unknown function; YMR187C is not an essential gene Uncharacterized chr13:634688-635983 634688-635983 99.1% 50.59 63.05 38.14 31.91 21.02 21.79 56.82 35.03 21.40 0.21 0.14 0.09 -0.71 -0.38 Matched[4549]
YMR188C MRPS17 Mitochondrial ribosomal protein of the small subunit Verified chr13:636290-637003 636290-637003 99.5% 408.35 408.35 477.35 442.15 450.60 267.54 408.35 459.75 359.07 1.51 1.87 1.49 -0.36 -0.62 Frag>80[4550,4551]
YMR189W GCV2 "P subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of 5,10-methylene-THF in the cytoplasm" Verified chr13:637499-640603 637499-640603 98.9% 628.53 529.58 686.79 558.55 173.49 125.32 579.05 622.67 149.40 2.14 2.53 0.62 -2.06 -1.52 Matched[4552]
YMR190C SGS1 "Nucleolar DNA helicase of the RecQ family involved in maintenance of genome integrity, regulates chromosome synapsis and meiotic crossing over; has similarity to human BLM and WRN helicases implicated in Bloom and Werner syndromes" Verified chr13:640914-645257 640914-645257 99.2% 56.17 54.54 50.36 45.95 41.54 65.68 55.35 48.16 53.61 0.20 0.20 0.22 0.15 1.06 Matched[4553]
YMR191W SPG5 Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources Verified chr13:645655-646776 645655-646776 98.9% 145.97 144.17 163.09 167.59 267.61 167.59 145.07 165.34 217.60 0.54 0.67 0.90 0.40 0.55 Frag>80[4554,4555]
YMR192W GYL1 "Putative GTPase activating protein (GAP) that may have a role in polarized exocytosis; stimulates Gyp5p GAP activity on Ypt1p, colocalizes with Gyp5p at sites of polarized growth; interacts with Gyp5p, Rvs161p, and Rvs167p" Verified chr13:647117-649279 647117-649279 98.8% 108.05 98.69 88.40 70.63 84.19 81.86 103.37 79.52 83.02 0.38 0.32 0.34 0.06 -0.40 Matched[4556]
YMR193W MRPL24 Mitochondrial ribosomal protein of the large subunit Verified chr13:650035-650811 650035-650811 98.5% 240.44 232.60 308.40 233.91 297.94 193.40 236.52 271.15 245.67 0.87 1.10 1.02 -0.14 -0.03 Matched[4557]
YMR194W RPL36A "N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl36Bp and has similarity to rat L36 ribosomal protein; binds to 5.8 S rRNA" Verified chr13:651144-651909 651144-651159,651623-651909 71.6% 3621.42 2870.42 2962.56 2142.45 612.79 354.77 3245.92 2552.51 483.78 11.98 10.36 2.00 -2.40 -3.14 Matched[4558]
YMR193C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr13:651071-651457 651071-651457 98.7% 144.03 120.46 133.55 75.94 20.95 5.24 132.24 104.75 13.09 0.49 0.43 0.05 -3.00 -0.15 Matched[4558]
YMR194C-B Putative protein of unknown function Uncharacterized chr13:652593-652886 652593-652774,652847-652886 98.8% 91.20 182.41 232.57 155.04 975.87 433.21 136.80 193.81 704.54 0.51 0.79 2.92 1.86 NaN Matched[4560]
YMR194C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr13:652911-653135 652911-653135 98.6% 27.04 40.56 76.61 40.56 135.19 63.09 33.80 58.58 99.14 0.12 0.24 0.41 0.76 1.11 Matched[4560]
YMR195W ICY1 "Protein of unknown function, required for viability in rich media of cells lacking mitochondrial DNA; mutants have an invasive growth defect with elongated morphology; induced by amino acid starvation" Verified chr13:654033-654416 654033-654416 98.8% 416.38 1025.15 811.68 838.04 2105.63 961.90 720.76 824.86 1533.77 2.66 3.35 6.35 0.89 0.70 Matched[4562]
YMR196W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YMR196W is not an essential gene Uncharacterized chr13:655075-658341 655075-658341 98.6% 84.44 279.10 212.35 222.59 1599.44 1454.15 181.77 217.47 1526.80 0.67 0.88 6.33 2.81 2.60 Frag>80[4563,4564,4565]
YMR197C VTI1 "Protein involved in cis-Golgi membrane traffic; v-SNARE that interacts with two t-SNARES, Sed5p and Pep12p; required for multiple vacuolar sorting pathways" Verified chr13:658544-659197 658544-659197 99.3% 204.84 204.84 218.70 243.34 554.45 318.81 204.84 231.02 436.63 0.76 0.94 1.81 0.92 1.31 Matched[4566]
YMR198W CIK1 "Kinesin-associated protein required for both karyogamy and mitotic spindle organization, interacts stably and specifically with Kar3p and may function to target this kinesin to a specific cellular role; has similarity to Vik1p" Verified chr13:659744-661528 659744-661528 98.5% 90.48 96.17 97.30 96.17 88.20 85.35 93.32 96.74 86.78 0.34 0.39 0.36 -0.16 0.19 Covered/w/another[4567]
YMR199W CLN1 "G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)" Verified chr13:662643-664283 662643-664283 99.1% 312.47 286.64 329.69 226.97 91.03 46.75 299.55 278.33 68.89 1.11 1.13 0.29 -2.01 -1.59 Covered/w/another[4567]
YMR200W ROT1 "Essential ER membrane protein; may be involved in protein folding; mutation causes defects in cell wall synthesis and in lysis of autophagic bodies, suppresses tor2 mutations, and is synthetically lethal with kar2-1 and with rot2 mutations" Verified chr13:664751-665521 664751-665521 98.9% 393.44 533.77 489.18 392.13 641.31 480.00 463.61 440.66 560.66 1.71 1.79 2.32 0.35 0.80 Matched[4568]
YMR201C RAD14 Protein that recognizes and binds damaged DNA during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); contains zinc finger motif; homolog of human XPA protein Verified chr13:665844-667043 665844-666932,667017-667043 99.4% 89.28 74.85 58.62 50.50 157.82 100.10 82.07 54.56 128.96 0.30 0.22 0.53 1.24 0.87 Matched[4569]
YMR202W ERG2 "C-8 sterol isomerase, catalyzes the isomerization of the delta-8 double bond to the delta-7 position at an intermediate step in ergosterol biosynthesis" Verified chr13:667536-668204 667536-668204 98.8% 1033.22 1116.42 939.43 927.32 593.00 352.47 1074.82 933.38 472.74 3.97 3.79 1.96 -0.98 -0.78 Matched[4570]
YMR203W TOM40 Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; constitutes the core element of the protein conducting pore Verified chr13:668491-669654 668491-669654 99.0% 906.92 818.40 933.83 867.00 772.40 696.90 862.66 900.41 734.65 3.18 3.65 3.04 -0.29 0.17 Matched[4571]
YMR204C INP1 Peripheral membrane protein of peroxisomes involved in peroxisomal inheritance Verified chr13:670062-671324 670062-671324 99.2% 81.44 83.04 64.67 74.25 83.04 66.27 82.24 69.46 74.65 0.30 0.28 0.31 0.10 -0.12 Matched[4572]
YMR205C PFK2 "Beta subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes" Verified chr13:671886-674765 671886-674765 98.6% 1275.39 1221.86 1160.57 1031.30 535.02 704.79 1248.62 1095.94 619.91 4.61 4.45 2.57 -0.82 -0.19 Frag>80[4573,4574]
YMR206W Putative protein of unknown function; YMR206W is not an essential gene Uncharacterized chr13:675895-676836 675895-676836 98.9% 19.33 37.59 23.63 31.14 80.54 45.10 28.46 27.38 62.82 0.11 0.11 0.26 1.20 0.54 Covered[4575]
YMR207C HFA1 "Mitochondrial acetyl-coenzyme A carboxylase, catalyzes the production of malonyl-CoA in mitochondrial fatty acid biosynthesis" Verified chr13:677192-683563 677192-683563 99.1% 65.42 74.45 52.27 50.05 27.40 34.69 69.93 51.16 31.05 0.26 0.21 0.13 -0.72 -0.59 Frag<80[4576]
YMR208W ERG12 "Mevalonate kinase, acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate" Verified chr13:684466-685797 684466-685797 99.0% 301.96 275.41 270.86 241.27 234.44 164.64 288.69 256.06 199.54 1.07 1.04 0.83 -0.36 -0.02 Matched[4577]
YMR209C Putative protein of unknown function; YMR209C is not an essential gene Uncharacterized chr13:685910-687283 685910-687283 99.1% 147.62 164.51 144.68 135.14 104.29 77.12 156.07 139.91 90.70 0.58 0.57 0.38 -0.63 -0.55 Matched[4578]
YMR210W "Putative acyltransferase with similarity to Eeb1p and Eht1p, has a minor role in medium-chain fatty acid ethyl ester biosynthesis; may be involved in lipid metabolism and detoxification" Verified chr13:687515-688864 687515-688864 98.8% 170.87 219.58 204.59 210.59 344.73 229.32 195.22 207.59 287.03 0.72 0.84 1.19 0.47 0.51 Matched[4579]
YMR211W DML1 "Essential protein involved in mtDNA inheritance, may also function in the partitioning of the mitochondrial organelle or in the segregation of chromosomes, exhibits regions similar to members of a GTPase family" Verified chr13:689082-690509 689082-690509 98.8% 63.06 74.39 47.47 43.22 65.18 37.55 68.72 45.34 51.37 0.25 0.18 0.21 0.18 -0.00 Matched[4580]
YMR212C EFR3 "Non-essential protein of unknown function; exhibits synthetic lethal genetic interactions with PHO85; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies and is phosphorylated" Verified chr13:690694-693042 690694-693042 99.3% 153.94 150.08 130.36 118.78 99.91 81.90 152.01 124.57 90.91 0.56 0.51 0.38 -0.45 -0.50 Matched[4581]
YMR213W CEF1 "Essential splicing factor; associated with Prp19p and the spliceosome, contains an N-terminal c-Myb DNA binding motif necessary for cell viability but not for Prp19p association, evolutionarily conserved and homologous to S. pombe Cdc5p" Verified chr13:693380-695152 693380-695152 98.3% 90.05 92.35 63.67 50.48 82.60 72.85 91.20 57.07 77.72 0.34 0.23 0.32 0.45 0.81 Matched[4582]
YMR214W SCJ1 "One of several homologs of bacterial chaperone DnaJ, located in the ER lumen where it cooperates with Kar2p to mediate maturation of proteins" Verified chr13:695349-696482 695349-696482 98.1% 243.50 203.96 212.05 168.92 339.64 268.65 223.73 190.48 304.14 0.83 0.77 1.26 0.68 1.01 Matched[4583]
YMR215W GAS3 "Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall" Verified chr13:696795-698369 696795-698369 99.1% 617.06 695.23 605.53 647.18 351.78 316.54 656.15 626.35 334.16 2.42 2.54 1.38 -0.91 -0.33 Matched[4584]
YMR216C SKY1 SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabolism and cation homeostasis; similar to human SRPK1 Verified chr13:698810-701038 698810-701038 99.1% 211.39 189.21 179.71 157.98 149.38 185.59 200.30 168.84 167.48 0.74 0.69 0.69 -0.01 0.57 Frag>80[4585,4586]
YMR217W GUA1 "GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation" Verified chr13:701789-703366 701789-703366 98.9% 1209.97 553.07 968.36 825.44 143.56 112.15 881.52 896.90 127.85 3.25 3.64 0.53 -2.81 -1.86 Matched[4587]
YMR218C TRS130 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in ER to Golgi membrane traffic; mutation activates transcription of OCH1 Verified chr13:703578-706886 703578-706886 99.3% 76.39 70.61 69.39 71.83 70.00 60.26 73.50 70.61 65.13 0.27 0.29 0.27 -0.12 -0.43 Matched[4588]
YMR219W ESC1 "Protein localized to the nuclear periphery, involved in telomeric silencing; interacts with PAD4-domain of Sir4p" Verified chr13:707132-712108 707132-712108 98.4% 122.74 143.78 120.90 129.48 114.57 166.45 133.26 125.19 140.51 0.49 0.51 0.58 0.17 0.83 Matched[4589]
YMR220W ERG8 "Phosphomevalonate kinase, an essential cytosolic enzyme that acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate" Verified chr13:712315-713670 712315-713670 98.7% 260.85 228.71 277.30 202.55 266.09 198.82 244.78 239.93 232.45 0.90 0.97 0.96 -0.05 0.31 Matched[4590]
YMR221C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr13:713930-715444 713930-715444 98.8% 205.75 173.02 228.46 172.35 86.17 60.79 189.38 200.41 73.48 0.70 0.81 0.30 -1.45 -1.04 Matched[4591]
YMR222C FSH2 Serine hydrolase that localizes to the cytoplasm; sequence is similar to Fsh1p and Fsh3p Verified chr13:715637-716308 715637-716308 98.8% 182.23 152.11 156.63 180.72 191.27 150.60 167.17 168.67 170.93 0.62 0.68 0.71 0.02 0.15 Matched[4592]
YMR223W UBP8 Ubiquitin-specific protease that is a component of the SAGA (Spt-Ada-Gcn5-Acetyltransferase) acetylation complex; required for SAGA-mediated deubiquitination of histone H2B Verified chr13:716714-718129 716714-718129 98.9% 93.51 81.38 92.80 78.52 54.25 54.97 87.45 85.66 54.61 0.32 0.35 0.23 -0.65 -0.32 Covered/w/another[4593]
YMR224C MRE11 "Subunit of a complex with Rad50p and Xrs2p (RMX complex) that functions in repair of DNA double-strand breaks and in telomere stability, exhibits nuclease activity that appears to be required for RMX function; widely conserved" Verified chr13:718574-720652 718574-720652 99.2% 53.36 55.30 58.70 42.69 44.63 39.78 54.33 50.69 42.20 0.20 0.21 0.17 -0.26 0.22 Covered/w/another[4593]
YMR225C MRPL44 Mitochondrial ribosomal protein of the large subunit Verified chr13:720959-721402 720959-721197,721345-721402 99.1% 424.63 424.63 349.89 380.47 407.64 227.60 424.63 365.18 317.62 1.57 1.48 1.32 -0.20 -0.26 Frag>80[4594,4595]
YMR226C "NADP(+)-dependent dehydrogenase; acts on serine, L-allo-threonine, and other 3-hydroxy acids; green fluorescent protein fusion protein localizes to the cytoplasm and nucleus; may interact with ribosomes, based on co-purification experiments" Verified chr13:721592-722395 721592-722395 99.0% 1010.88 870.24 930.51 897.87 1284.64 989.54 940.56 914.19 1137.09 3.47 3.71 4.71 0.31 0.53 Matched[4596]
YMR227C TAF7 "TFIID subunit (67 kDa), involved in RNA polymerase II transcription initiation" Verified chr13:722612-724384 722612-724384 99.1% 111.59 100.20 83.12 76.86 58.07 57.50 105.89 79.99 57.79 0.39 0.32 0.24 -0.47 0.41 Matched[4597]
YMR228W MTF1 "Mitochondrial RNA polymerase specificity factor with structural similarity to S-adenosylmethionine-dependent methyltransferases and functional similarity to bacterial sigma-factors, interacts with mitochondrial core polymerase Rpo41p" Verified chr13:724625-725650 724625-725650 99.0% 106.29 90.54 89.56 68.89 80.70 50.19 98.41 79.22 65.44 0.36 0.32 0.27 -0.28 -0.12 Matched[4598]
YMR229C RRP5 Protein required for the synthesis of both 18S and 5.8S rRNA; C-terminal region is crucial for the formation of 18S rRNA and N-terminal region is required for the 5.8S rRNA; component of small ribosomal subunit (SSU) processosome Verified chr13:725933-731122 725933-731122 99.2% 277.54 148.77 182.37 147.02 17.09 9.13 213.15 164.70 13.11 0.79 0.67 0.05 -3.65 -2.82 Frag>80[4599,4600,4601]
YMR230W RPS10B Protein component of the small (40S) ribosomal subunit; nearly identical to Rps10Ap and has similarity to rat ribosomal protein S10 Verified chr13:732413-733140 732413-732464,732875-733140 68.2% 6008.07 4836.89 4509.51 4315.85 1922.77 1480.12 5422.48 4412.68 1701.44 20.02 17.91 7.05 -1.37 -1.83 Matched[4603]
YMR230W-A Putative protein of unknown function Uncharacterized chr13:733267-733455 733267-733455 99.5% 10.63 5.32 10.63 10.63 10.63 5.32 7.97 10.63 7.97 0.03 0.04 0.03 -0.42 NaN Overlap[4603]
YMR231W PEP5 Component of CORVET tethering complex; peripheral vacuolar membrane protein required for protein trafficking and vacuole biogenesis; interacts with Pep7p Verified chr13:733544-736633 733544-736633 98.9% 70.06 102.14 71.04 70.06 60.56 51.72 86.10 70.55 56.14 0.32 0.29 0.23 -0.33 0.18 Frag>80[4604,4605]
YMR232W FUS2 Cytoplasmic protein localized to the shmoo tip; required for the alignment of parental nuclei before nuclear fusion during mating Verified chr13:736925-738958 736925-738958 98.9% 25.84 22.36 18.89 16.40 55.17 32.30 24.10 17.64 43.73 0.09 0.07 0.18 1.31 0.92 Frag>80[4605,4606]
YMR233W TRI1 "Non-essential sumoylated protein of unknown function with similarity to components of human SWI/SNF complex including SMRD3; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm, nucleus and nucleolus" Verified chr13:739184-739864 739184-739864 98.4% 201.37 167.06 162.59 114.85 161.09 82.04 184.21 138.72 121.57 0.68 0.56 0.50 -0.19 -0.36 Matched[4607]
YMR234W RNH1 "Ribonuclease H1, removes RNA primers during Okazaki fragment synthesis; degrades RNA attached to the 5'-end of a DNA strand" Verified chr13:740265-741311 740265-741311 98.7% 189.61 131.57 151.88 120.92 117.05 68.68 160.59 136.40 92.87 0.59 0.55 0.38 -0.55 -0.66 Matched[4608]
YMR235C RNA1 "GTPase activating protein (GAP) for Gsp1p, involved in nuclear transport" Verified chr13:741511-742734 741511-742734 99.2% 831.31 640.99 685.48 654.99 455.61 284.24 736.15 670.24 369.93 2.72 2.72 1.53 -0.86 -0.59 Matched[4609]
YMR236W TAF9 "Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H3" Verified chr13:742970-743443 742970-743443 98.4% 381.70 407.43 456.75 338.81 435.31 332.38 394.57 397.78 383.85 1.46 1.61 1.59 -0.05 0.07 Matched[4610]
YMR237W BCH1 "Member of the Chs5p-Arf1p-binding proteins (ChAPs), a group of 4 related, interacting proteins (Bch1p, Fmp50p, Bud7p, Chs6p) that mediate export of specific cargo proteins, including chitin synthase Chs3p; may interact with ribosomes" Verified chr13:743748-745922 743748-745922 98.8% 246.71 266.26 242.52 228.56 381.71 393.81 256.49 235.54 387.76 0.95 0.96 1.61 0.72 0.97 Matched[4611]
YMR238W DFG5 "Putative mannosidase, essential glycosylphosphatidylinositol (GPI)-anchored membrane protein required for cell wall biogenesis in bud formation, involved in filamentous growth, homologous to Dcw1p" Verified chr13:746352-747728 746352-747728 98.6% 240.84 240.84 223.90 240.84 178.97 94.27 240.84 232.37 136.62 0.89 0.94 0.57 -0.77 -0.72 Matched[4612]
YMR239C RNT1 RNAase III; involved in rDNA transcription and rRNA processing; also cleaves a stem-loop structure at the 3' end of U2 snRNA to ensure formation of the correct U2 3' end Verified chr13:748261-749676 748261-749676 99.4% 105.11 66.76 68.89 50.42 10.65 1.42 85.93 59.66 6.04 0.32 0.24 0.03 -3.30 -3.17 Matched[4613]
YMR240C CUS1 "Protein required for assembly of U2 snRNP into the spliceosome, forms a complex with Hsh49p and Hsh155p" Verified chr13:749929-751239 749929-751239 99.3% 86.04 100.64 76.82 77.59 53.01 47.63 93.34 77.21 50.32 0.34 0.31 0.21 -0.62 -0.20 Matched[4614]
YMR241W YHM2 "Mitochondrial DNA-binding protein, component of the mitochondrial nucleoid structure, involved in mtDNA replication and segregation of mitochondrial genomes; member of the mitochondrial carrier protein family" Verified chr13:751960-752904 751960-752904 98.6% 803.50 719.83 844.27 666.19 230.65 143.75 761.67 755.23 187.20 2.81 3.07 0.78 -2.01 -2.09 Matched[4615]
YMR242C RPL20A "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl20Bp and has similarity to rat L18a ribosomal protein" Verified chr13:753224-754219 753224-753741,754219-754219 51.5% 5867.25 4618.26 5074.48 3825.49 785.29 437.52 5242.75 4449.98 611.41 19.35 18.06 2.53 -2.86 -2.75 Frag>80[4616,4617]
YMR242W-A Putative protein of unknown function Uncharacterized chr13:754296-754385 754296-754385 97.8% 45.43 0.00 22.72 11.36 22.72 34.07 22.72 17.04 28.40 0.08 0.07 0.12 0.74 NaN Covered/w/another[4617]
YMR243C ZRC1 "Vacuolar membrane zinc transporter, transports zinc from the cytosol into the vacuole for storage; also has a role in resistance to zinc shock resulting from a sudden influx of zinc into the cytoplasm" Verified chr13:754837-756165 754837-756165 98.8% 668.68 584.90 606.99 530.83 329.77 284.07 626.79 568.91 306.92 2.31 2.31 1.27 -0.89 -0.50 Frag>80[4618,4619]
YMR244W Putative protein of unknown function Uncharacterized chr13:757249-758316 757249-758316 98.3% 11.43 20.01 5.72 6.67 6.67 27.63 15.72 6.19 17.15 0.06 0.03 0.07 1.47 -0.58 Frag<80[4620,4621]
YMR245W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr13:758562-759182 758562-759182 99.0% 113.81 175.60 112.19 136.58 190.23 160.96 144.71 124.38 175.60 0.53 0.50 0.73 0.50 -0.16 Frag>80[4621,4622]
YMR244C-A Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus and is induced in response to the DNA-damaging agent MMS; YMR244C-A is not an essential gene Uncharacterized chr13:758516-758830 758516-758830 99.1% 224.18 291.43 198.56 224.18 381.10 281.83 257.81 211.37 331.47 0.95 0.86 1.37 0.65 0.24 Matched[4621]
YMR246W FAA4 "Long chain fatty acyl-CoA synthetase, regulates protein modification during growth in the presence of ethanol, functions to incorporate palmitic acid into phospholipids and neutral lipids" Verified chr13:759806-761890 759806-761890 97.3% 511.52 1492.67 453.86 416.41 62.58 33.02 1002.09 435.14 47.80 3.70 1.77 0.20 -3.19 -2.54 Matched[4623]
YMR247C RKR1 "Nuclear RING domain protein with functional connections to chromatin modification; may interact with ribosomes, based on co-purification experiments; YMR247C is not an essential gene" Verified chr13:763350-768038 763350-768038 99.2% 78.27 68.16 62.57 60.21 42.15 50.75 73.22 61.39 46.45 0.27 0.25 0.19 -0.40 -0.14 Frag>80[4625]
YMR247W-A Putative protein of unknown function Uncharacterized chr13:769282-769425 769282-769425 99.1% 28.04 21.03 14.02 49.07 126.17 154.21 24.53 31.54 140.19 0.09 0.13 0.58 2.15 NaN Covered[4626]
YMR250W GAD1 "Glutamate decarboxylase, converts glutamate into gamma-aminobutyric acid (GABA) during glutamate catabolism; involved in response to oxidative stress" Verified chr13:770800-772557 770800-772557 98.7% 172.38 686.65 363.79 432.40 3858.75 3503.03 429.52 398.10 3680.89 1.59 1.62 15.25 3.21 3.26 Matched[4627]
YMR251W GTO3 Omega class glutathione transferase; putative cytosolic localization Verified chr13:772914-774014 772914-774014 98.4% 16.62 34.17 13.85 20.31 84.95 50.79 25.39 17.08 67.87 0.09 0.07 0.28 1.99 1.18 Matched[4628]
YMR251W-A HOR7 Protein of unknown function; overexpression suppresses Ca2+ sensitivity of mutants lacking inositol phosphorylceramide mannosyltransferases Csg1p and Csh1p; transcription is induced under hyperosmotic stress and repressed by alpha factor Verified chr13:774751-774930 774751-774930 98.9% 8969.81 22129.65 10143.69 10840.16 99212.73 50982.45 15549.73 10491.93 75097.59 57.40 42.59 311.15 2.84 0.37 Matched[4630]
YMR252C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YMR252C is not an essential gene Uncharacterized chr13:775314-775718 775314-775718 99.1% 196.88 284.11 241.74 186.92 229.28 166.98 240.50 214.33 198.13 0.89 0.87 0.82 -0.11 0.35 Covered/w/another[4631]
YMR253C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; YMR253C is not an essential gene Uncharacterized chr13:775945-777189 775945-777189 99.1% 70.54 128.10 90.81 84.32 131.35 99.73 99.32 87.56 115.54 0.37 0.36 0.48 0.40 0.73 Matched[4631]
YMR254C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr13:777614-777922 777614-777922 98.9% 19.64 29.46 16.37 22.91 26.19 22.91 24.55 19.64 24.55 0.09 0.08 0.10 0.32 0.43 Matched[4632]
YMR255W GFD1 "Coiled-coiled protein of unknown function, identified as a high-copy suppressor of a dbp5 mutation" Verified chr13:778000-778566 778000-778566 98.6% 336.36 402.56 361.41 309.53 409.72 311.32 369.46 335.47 360.52 1.36 1.36 1.49 0.10 0.24 Matched[4633]
YMR256C COX7 "Subunit VII of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain" Verified chr13:778944-779126 778944-779126 98.7% 653.29 420.76 669.90 780.62 1832.53 1074.05 537.02 725.26 1453.29 1.98 2.94 6.02 1.00 -0.05 Matched[4634]
YMR257C PET111 Mitochondrial translational activator specific for the COX2 mRNA; located in the mitochondrial inner membrane Verified chr13:779628-782030 779628-782030 99.3% 62.43 65.78 59.92 56.14 61.17 39.80 64.11 58.03 50.49 0.24 0.24 0.21 -0.20 0.10 Frag>80[4635,4636]
YMR258C Protein of unknown function with similarity to F-box proteins; physically interacts with Skp1p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YMR258C is not an essential gene Uncharacterized chr13:782619-784280 782619-784280 99.2% 126.12 138.24 129.76 107.32 345.01 298.92 132.18 118.54 321.96 0.49 0.48 1.33 1.44 1.76 Matched[4637]
YMR259C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YMR259C is not an essential gene Uncharacterized chr13:784620-788882 784620-788882 99.1% 88.27 67.45 53.25 39.05 14.44 14.20 77.86 46.15 14.32 0.29 0.19 0.06 -1.69 -1.06 Frag>80[4638]
YMR260C TIF11 "Translation initiation factor eIF1A, essential protein that forms a complex with Sui1p (eIF1) and the 40S ribosomal subunit and scans for the start codon; C-terminus associates with Fun12p (eIF5B); N terminus interacts with eIF2 and eIF3" Verified chr13:789377-789838 789377-789838 99.5% 2709.19 1819.90 2133.00 2011.23 1174.13 828.41 2264.54 2072.11 1001.27 8.36 8.41 4.15 -1.05 -1.40 Matched[4639]
YMR261C TPS3 "Regulatory subunit of trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway" Verified chr13:790204-793368 790204-793368 98.9% 175.67 247.22 240.19 259.68 542.67 621.24 211.45 249.93 581.95 0.78 1.01 2.41 1.22 1.62 Frag>80[4640,4641]
YMR262W Protein of unknown function; interacts weakly with Knr4p; YMR262W is not an essential gene Uncharacterized chr13:793725-794666 793725-794666 98.5% 100.21 144.38 133.61 110.98 411.60 221.96 122.30 122.30 316.78 0.45 0.50 1.31 1.37 1.46 Matched[4642]
YMR263W SAP30 "Subunit of a histone deacetylase complex, along with Rpd3p and Sin3p, that is involved in silencing at telomeres, rDNA, and silent mating-type loci; involved in telomere maintenance" Verified chr13:794918-795523 794918-795523 95.4% 179.98 188.64 200.75 150.56 134.99 69.22 184.31 175.66 102.11 0.68 0.71 0.42 -0.78 -0.80 Frag>80[4643,4644]
YMR264W CUE1 Endoplasmic reticulum membrane protein that recruits the ubiquitin-conjugating enzyme Ubc7p to the ER where it functions in protein degradation; contains a CUE domain that binds ubiquitin to facilitate intramolecular monoubiquitination Verified chr13:795804-796415 795804-796415 98.3% 395.49 508.48 363.91 345.63 731.15 480.23 451.98 354.77 605.69 1.67 1.44 2.51 0.77 0.25 Matched[4645]
YMR265C Putative protein of unknown function Uncharacterized chr13:796539-797924 796539-797924 98.9% 61.99 59.80 52.51 41.57 74.39 54.70 60.90 47.04 64.54 0.22 0.19 0.27 0.46 0.60 Matched[4646]
YMR266W RSN1 Membrane protein of unknown function; overexpression suppresses NaCl sensitivity of sro7 mutant Verified chr13:798517-801378 798517-801378 99.0% 254.95 209.04 221.75 204.45 79.80 93.57 231.99 213.10 86.69 0.86 0.87 0.36 -1.30 -0.60 Matched[4647]
YMR267W PPA2 "Mitochondrial inorganic pyrophosphatase, required for mitochondrial function and possibly involved in energy generation from inorganic pyrophosphate" Verified chr13:801771-802703 801771-802703 98.7% 229.08 217.14 267.08 260.56 365.87 226.91 223.11 263.82 296.39 0.82 1.07 1.23 0.17 0.11 Matched[4648]
YMR268C PRP24 Splicing factor that reanneals U4 and U6 snRNPs during spliceosome recycling Verified chr13:802887-804221 802887-804221 99.3% 52.08 46.04 45.28 31.70 27.92 23.40 49.06 38.49 25.66 0.18 0.16 0.11 -0.58 -0.40 Matched[4649]
YMR269W TMA23 Nucleolar protein of unknown function implicated in ribosome biogenesis; TMA23 may be a fungal-specific gene as no homologs have been yet identified in higher eukaryotes Verified chr13:804455-805090 804455-805090 97.8% 279.78 202.60 130.24 122.20 64.32 32.16 241.19 126.22 48.24 0.89 0.51 0.20 -1.39 -0.10 Frag>80[4650,4651]
YMR270C RRN9 "Protein involved in promoting high level transcription of rDNA, subunit of UAF (upstream activation factor) for RNA polymerase I" Verified chr13:805325-806422 805325-806422 99.3% 194.41 164.14 162.31 168.73 138.47 83.45 179.28 165.52 110.96 0.66 0.67 0.46 -0.58 -0.41 Matched[4652]
YMR271C URA10 "One of two orotate phosphoribosyltransferase isozymes (see also URA5) that catalyze the fifth enzymatic step in the de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate" Verified chr13:806864-807547 806864-807547 99.3% 72.12 163.38 67.71 92.73 322.34 197.23 117.75 80.22 259.78 0.43 0.33 1.08 1.70 1.49 Matched[4653]
YMR272W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene SCS7/YMR272C" Dubious chr13:810465-810578 810465-810578 99.5% 679.16 1129.00 723.26 926.13 511.58 529.22 904.08 824.70 520.40 3.34 3.35 2.16 -0.66 NaN Covered/w/another[4655]
YMR272C SCS7 "Sphingolipid alpha-hydroxylase, functions in the alpha-hydroxylation of sphingolipid-associated very long chain fatty acids, has both cytochrome b5-like and hydroxylase/desaturase domains, not essential for growth" Verified chr13:809622-810776 809622-810776 98.7% 695.56 1166.58 797.31 861.34 528.91 515.75 931.07 829.33 522.33 3.44 3.37 2.16 -0.67 -0.21 Matched[4655]
YMR272W-B "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr13:811088-811195 811088-811195 98.6% 28.18 28.18 37.57 9.39 18.79 18.79 28.18 23.48 18.79 0.10 0.10 0.08 -0.32 NaN Matched[4656]
YMR273C ZDS1 "Protein that interacts with silencing proteins at the telomere, involved in transcriptional silencing; has a role in localization of Bcy1p, a regulatory subunit of protein kinase A; implicated in mRNA nuclear export" Verified chr13:811232-813979 811232-813979 98.9% 94.17 104.47 80.93 91.60 93.07 99.69 99.32 86.26 96.38 0.37 0.35 0.40 0.16 0.69 Frag>80[4656,4657]
YMR274C RCE1 Type II CAAX prenyl protease involved in the proteolysis and maturation of Ras and the a-factor mating pheromone Verified chr13:814363-815310 814363-815310 98.8% 88.58 102.45 90.72 77.91 74.71 41.62 95.52 84.31 58.16 0.35 0.34 0.24 -0.54 -0.22 Matched[4658]
YMR275C BUL1 "Ubiquitin-binding component of the Rsp5p E3-ubiquitin ligase complex, functional homolog of Bul2p, disruption causes temperature-sensitive growth, overexpression causes missorting of amino acid permeases" Verified chr13:815650-818580 815650-818580 99.0% 112.38 101.35 111.35 90.66 128.93 118.93 106.87 101.01 123.93 0.39 0.41 0.51 0.30 0.32 Matched[4659]
YMR276W DSK2 "Nuclear-enriched ubiquitin-like polyubiquitin-binding protein, required for spindle pole body (SPB) duplication and for transit through the G2/M phase of the cell cycle, involved in proteolysis, interacts with the proteasome" Verified chr13:818826-819947 818826-819947 98.4% 627.84 518.21 674.95 607.90 1099.85 901.44 573.02 641.43 1000.64 2.12 2.60 4.15 0.64 0.84 Matched[4660]
YMR277W FCP1 "Carboxy-terminal domain (CTD) phosphatase, essential for dephosphorylation of the repeated C-terminal domain of the RNA polymerase II large subunit (Rpo21p)" Verified chr13:820255-822453 820255-822453 98.4% 210.67 191.26 182.95 131.67 149.69 132.59 200.97 157.31 141.14 0.74 0.64 0.58 -0.16 0.44 Matched[4661]
YMR278W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YMR278W is not an essential gene Uncharacterized chr13:822762-824630 822762-824630 98.8% 141.28 195.40 160.76 207.31 400.55 446.02 168.34 184.04 423.28 0.62 0.75 1.75 1.20 1.45 Matched[4662]
YMR279C Putative protein of unknown function; identified as a heat-induced gene in a high-throughout screen; YMR279C is not an essential gene Uncharacterized chr13:824728-826350 824728-826350 98.9% 70.99 128.91 59.78 62.90 134.51 164.40 99.95 61.34 149.46 0.37 0.25 0.62 1.28 0.71 Covered/w/another[4663]
YMR280C CAT8 "Zinc cluster transcriptional activator necessary for derepression of a variety of genes under non-fermentative growth conditions, active after diauxic shift, binds carbon source responsive elements" Verified chr13:827027-831328 827027-831328 99.1% 32.38 49.27 26.98 30.50 34.02 40.82 40.82 28.74 37.42 0.15 0.12 0.16 0.38 1.05
YMR281W GPI12 "ER membrane protein involved in the second step of glycosylphosphatidylinositol (GPI) anchor assembly, the de-N-acetylation of the N-acetylglucosaminylphosphatidylinositol intermediate; functional homolog of human PIG-Lp" Verified chr13:832338-833252 832338-833252 99.1% 84.93 82.73 108.10 82.73 175.38 124.64 83.83 95.41 150.01 0.31 0.39 0.62 0.65 0.56 Covered/w/another[4664]
YMR282C AEP2 "Mitochondrial protein, likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader" Verified chr13:833355-835097 833355-835097 99.2% 116.24 112.77 88.48 98.31 98.89 66.51 114.51 93.40 82.70 0.42 0.38 0.34 -0.18 -0.42 Covered/w/another[4664]
YMR283C RIT1 "2'-O-ribosyl phosphate transferase, modifies the initiator methionine tRNA at position 64 to distinguish it from elongator methionine tRNA" Verified chr13:835325-836866 835325-836866 99.2% 56.85 56.20 61.42 60.12 50.97 37.25 56.52 60.77 44.11 0.21 0.25 0.18 -0.46 -0.19 Matched[4665]
YMR284W YKU70 "Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair" Verified chr13:838186-839994 838186-839994 98.9% 77.16 98.41 94.49 91.70 246.58 178.36 87.78 93.09 212.47 0.32 0.38 0.88 1.19 0.91 Matched[4666]
YMR285C NGL2 Protein involved in 5.8S rRNA processing; Ccr4p-like RNase required for correct 3'-end formation of 5.8S rRNA at site E; similar to Ngl1p and Ngl3p Verified chr13:840143-841690 840143-841690 99.2% 154.94 167.31 153.64 97.00 85.93 60.54 161.12 125.32 73.24 0.59 0.51 0.30 -0.77 -0.33 Matched[4667]
YMR286W MRPL33 Mitochondrial ribosomal protein of the large subunit Verified chr13:841941-842201 841941-842201 98.1% 609.57 386.84 476.72 390.75 441.55 277.43 498.21 433.73 359.49 1.84 1.76 1.49 -0.27 -0.30 Matched[4668]
YMR287C DSS1 "3'-5' exoribonuclease, component of the mitochondrial degradosome along with the ATP-dependent RNA helicase Suv3p; the degradosome associates with the ribosome and mediates turnover of aberrant or unprocessed RNAs" Verified chr13:842435-845344 842435-845344 99.2% 55.09 57.86 50.24 52.67 48.85 41.23 56.48 51.45 45.04 0.21 0.21 0.19 -0.19 0.26 Frag>80[4668,4669,4670]
YMR288W HSH155 U2-snRNP associated splicing factor that forms extensive associations with the branch site-3' splice site-3' exon region upon prespliceosome formation; similarity to the mammalian U2 snRNP-associated splicing factor SAP155 Verified chr13:845570-848485 845570-848485 98.8% 70.14 51.73 38.19 44.79 33.68 31.94 60.94 41.49 32.81 0.22 0.17 0.14 -0.34 0.37 Frag>80[4671]
YMR289W ABZ2 "Aminodeoxychorismate lyase (4-amino-4-deoxychorismate lyase), catalyzes the third step in para-aminobenzoic acid biosynthesis; involved in folic acid biosynthesis" Verified chr13:848684-849808 848684-849808 98.8% 178.21 226.81 184.51 161.11 177.31 150.31 202.51 172.81 163.81 0.75 0.70 0.68 -0.08 -0.12 Matched[4672]
YMR290W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps 5' end of essential HAS1 gene which encodes an ATP-dependent RNA helicase" Dubious chr13:851421-851768 851421-851768 98.7% 148.51 87.36 116.48 93.18 52.41 29.12 117.93 104.83 40.77 0.44 0.43 0.17 -1.36 -0.35 Frag<80[4674,4675]
YMR290C HAS1 ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles Verified chr13:850073-851590 850073-851590 99.1% 435.23 217.95 299.01 257.81 41.86 20.60 326.59 278.41 31.23 1.21 1.13 0.13 -3.16 -2.19 Matched[4673]
YMR291W Putative kinase of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YMR291W is not an essential gene Uncharacterized chr13:852629-854389 852629-854389 98.8% 259.20 294.83 330.47 256.33 475.87 372.42 277.02 293.40 424.15 1.02 1.19 1.76 0.53 0.74 Matched[4676]
YMR292W GOT1 "Evolutionarily conserved non-essential protein present in early Golgi cisternae that may be involved in ER-Golgi transport at a step after vesicle tethering to Golgi membranes, exhibits membrane topology similar to that of Sft2p" Verified chr13:854794-855292 854794-854815,854898-855292 99.5% 460.56 344.82 412.34 318.30 303.83 147.09 402.69 365.32 225.46 1.49 1.48 0.93 -0.70 -1.18 Frag>80[4677,4678]
YMR293C "Putative protein similar to bacterial glutamyl-tRNA amidotransferases; may be involved in aerobic respiration; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr13:855398-856792 855398-856792 99.0% 65.15 74.57 73.12 65.15 128.86 88.32 69.86 69.14 108.59 0.26 0.28 0.45 0.65 0.10 Matched[4679]
YMR294W JNM1 "Component of the yeast dynactin complex, consisting of Nip100p, Jnm1p, and Arp1p; required for proper nuclear migration and spindle partitioning during mitotic anaphase B" Verified chr13:856965-858086 856965-858086 98.2% 79.85 80.76 76.22 58.98 116.14 67.15 80.30 67.60 91.64 0.30 0.27 0.38 0.44 -0.07 Matched[4680]
YMR294W-A "Dubious open reading frame unlikely to encode a functional protein, substantially overlaps YMR295C; deletion causes sensitivity to unfolded protein response-inducing agents" Dubious chr13:858208-858567 858208-858567 98.9% 980.45 969.21 977.64 887.74 1320.38 806.27 974.83 932.69 1063.33 3.60 3.79 4.41 0.19 0.03 Matched[4681]
YMR295C Protein of unknown function that associates with ribosomes; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and bud; YMR295C is not an essential gene Verified chr13:858296-858889 858296-858889 98.8% 972.47 1015.04 962.25 877.09 1209.20 807.27 993.76 919.67 1008.23 3.67 3.73 4.18 0.13 -0.01 Frag>80[4681,4682]
YMR296C LCB1 "Component of serine palmitoyltransferase, responsible along with Lcb2p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine" Verified chr13:859214-860890 859214-860890 98.4% 492.67 404.80 442.37 398.74 273.30 220.58 448.73 420.55 246.94 1.66 1.71 1.02 -0.77 -0.09 Matched[4683]
YMR297W PRC1 "Vacuolar carboxypeptidase Y (proteinase C), broad-specificity C-terminal exopeptidase involved in non-specific protein degradation in the vacuole; member of the serine carboxypeptidase family" Verified chr13:861921-863519 861921-863519 98.7% 1382.87 2154.80 1550.82 1475.40 2388.66 2508.44 1768.83 1513.11 2448.55 6.53 6.14 10.15 0.69 0.79 Matched[4684]
YMR298W LIP1 "Ceramide synthase subunit; single-span ER membrane protein associated with Lag1p and Lac1p and required for ceramide synthase activity, null mutant grows extremely slowly and is defective in ceramide synthesis" Verified chr13:863818-864270 863818-864270 98.9% 696.30 874.84 620.42 716.38 758.79 540.08 785.57 668.40 649.43 2.90 2.71 2.69 -0.04 -0.29 Matched[4685]
YMR299C DYN3 "Dynein light intermediate chain (LIC); localizes with dynein, null mutant is defective in nuclear migration" Verified chr13:864411-865349 864411-865349 99.4% 156.43 161.79 135.00 102.86 117.86 79.29 159.11 118.93 98.57 0.59 0.48 0.41 -0.27 -0.71 Matched[4686]
YMR300C ADE4 "Phosphoribosylpyrophosphate amidotransferase (PRPPAT; amidophosphoribosyltransferase), catalyzes first step of the 'de novo' purine nucleotide biosynthetic pathway" Verified chr13:865558-867090 865558-867090 99.3% 1306.94 989.57 1287.23 921.23 188.58 87.39 1148.25 1104.23 137.99 4.24 4.48 0.57 -3.00 -3.09 Matched[4687]
YMR301C ATM1 "Mitochondrial inner membrane ATP-binding cassette (ABC) transporter, exports mitochondrially synthesized precursors of iron-sulfur (Fe/S) clusters to the cytosol" Verified chr13:867554-869626 867554-869626 99.0% 150.09 134.49 120.36 112.08 36.55 20.47 142.29 116.22 28.51 0.53 0.47 0.12 -2.03 -0.95 Matched[4688]
YMR302C YME2 Integral inner mitochondrial membrane protein with a role in maintaining mitochondrial nucleoid structure and number; mutants exhibit an increased rate of mitochondrial DNA escape; shows some sequence similarity to exonucleases Verified chr13:870072-872624 870072-872624 99.1% 147.07 166.44 170.40 170.00 254.61 241.56 156.76 170.20 248.09 0.58 0.69 1.03 0.54 0.81 Matched[4689]
YMR303C ADH2 "Glucose-repressible alcohol dehydrogenase II, catalyzes the conversion of ethanol to acetaldehyde; involved in the production of certain carboxylate esters; regulated by ADR1" Verified chr13:873290-874336 873290-874336 73.1% 24.84 20.92 16.99 19.61 15.69 14.38 22.88 18.30 15.03 0.08 0.07 0.06 -0.28 0.13
YMR304W UBP15 Ubiquitin-specific protease that may play a role in ubiquitin precursor processing Verified chr13:874986-878678 874986-878678 98.8% 114.01 137.58 135.11 135.93 201.98 240.62 125.79 135.52 221.30 0.46 0.55 0.92 0.71 1.22 Matched[4690]
YMR304C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene SCW10" Dubious chr13:878779-879129 878779-879129 97.2% 1143.42 677.25 900.07 759.35 225.75 85.02 910.33 829.71 155.39 3.36 3.37 0.64 -2.42 -2.35 Covered/w/another[4691]
YMR305C SCW10 Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on mutant phenotype and its regulation by Ste12p Verified chr13:879062-880231 879062-880231 98.0% 1314.48 871.38 1216.79 1078.10 122.99 29.66 1092.93 1147.45 76.32 4.03 4.66 0.32 -3.91 -3.49 Matched[4691]
YMR306W FKS3 "Protein involved in spore wall assembly, has similarity to 1,3-beta-D-glucan synthase catalytic subunits Fks1p and Gsc2p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr13:881158-886515 881158-886515 98.9% 13.59 16.99 10.76 7.17 13.02 9.44 15.29 8.97 11.23 0.06 0.04 0.05 0.32 1.27
YMR306C-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr13:886182-886571 886182-886571 98.9% 12.96 20.73 18.14 12.96 59.61 20.73 16.85 15.55 40.17 0.06 0.06 0.17 1.37 0.41
YMR307W GAS1 "Beta-1,3-glucanosyltransferase, required for cell wall assembly; localizes to the cell surface via a glycosylphosphatidylinositol (GPI) anchor" Verified chr13:887002-888681 887002-888681 99.0% 3665.58 3071.68 3211.74 3005.56 727.35 530.18 3368.63 3108.65 628.76 12.44 12.62 2.61 -2.31 -1.82 Matched[4692]
YMR307C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene GAS1/YMR307W" Dubious chr13:887730-887924 887730-887924 99.0% 3501.08 3200.69 3314.63 3128.18 678.46 637.03 3350.88 3221.41 657.75 12.37 13.08 2.73 -2.29 NaN Covered/w/another[4692]
YMR308C PSE1 "Karyopherin/importin that interacts with the nuclear pore complex; acts as the nuclear import receptor for specific proteins, including Pdr1p, Yap1p, Ste12p, and Aft1p" Verified chr13:888951-892220 888951-892220 99.1% 373.58 289.91 283.42 243.29 109.29 121.64 331.74 263.36 115.47 1.22 1.07 0.48 -1.19 -0.59 Matched[4693]
YMR309C NIP1 "Subunit of the eukaryotic translation initiation factor 3 (eIF3), involved in the assembly of preinitiation complex and start codon selection" Verified chr13:892987-895425 892987-895425 99.1% 540.93 402.39 415.63 366.41 86.85 88.09 471.66 391.02 87.47 1.74 1.59 0.36 -2.16 -1.66 Matched[4694]
YMR310C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YMR310C is not an essential gene Uncharacterized chr13:895715-896668 895715-896668 98.6% 166.87 88.22 88.22 98.85 17.01 5.31 127.55 93.53 11.16 0.47 0.38 0.05 -3.07 -3.08 Matched[4695]
YMR311C GLC8 "Regulatory subunit of protein phosphatase 1 (Glc7p), involved in glycogen metabolism and chromosome segregation; proposed to regulate Glc7p activity via conformational alteration; ortholog of the mammalian protein phosphatase inhibitor 2" Verified chr13:896913-897602 896913-897602 99.3% 553.42 624.97 589.92 587.00 1279.14 794.35 589.19 588.46 1036.75 2.17 2.39 4.30 0.82 0.52 Matched[4696]
YMR312W ELP6 "Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity" Verified chr13:898404-899225 898404-899225 99.3% 175.19 122.51 131.09 110.26 47.78 22.05 148.85 120.67 34.92 0.55 0.49 0.14 -1.79 -1.09 Matched[4697]
YMR313C TGL3 "Triacylglycerol lipase of the lipid particle, responsible for all the TAG lipase activity of the lipid particle; contains the consensus sequence motif GXSXG, which is found in lipolytic enzymes" Verified chr13:899378-901306 899378-901306 99.2% 123.91 134.89 123.39 111.89 137.51 127.57 129.40 117.64 132.54 0.48 0.48 0.55 0.17 0.07 Matched[4698]
YMR314W PRE5 20S proteasome alpha-type subunit Verified chr13:901708-902412 901708-902412 98.5% 865.42 820.78 861.10 871.18 1399.65 858.22 843.10 866.14 1128.94 3.11 3.52 4.68 0.38 0.56 Matched[4699]
YMR315W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YMR315W is not an essential gene Uncharacterized chr13:902799-903848 902799-903848 98.8% 555.00 824.80 590.65 593.54 1731.49 1275.73 689.90 592.10 1503.61 2.55 2.40 6.23 1.34 1.61 Frag>80[4700,4701]
YMR315W-A Putative protein of unknown function Uncharacterized chr13:904285-904392 904285-904392 98.4% 0.00 28.24 0.00 9.41 37.65 18.82 14.12 4.71 28.24 0.05 0.02 0.12 2.58 NaN Matched[4702]
YMR316W DIA1 "Protein of unknown function, involved in invasive and pseudohyphal growth; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" Verified chr13:904823-905833 904823-905833 98.6% 43.12 45.13 55.15 36.10 113.32 77.22 44.12 45.63 95.27 0.16 0.19 0.39 1.06 1.30 Matched[4703]
YMR316C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene DIA1/YMR316W" Dubious chr13:905660-905971 905660-905971 98.6% 35.74 51.99 71.49 13.00 90.98 45.49 43.87 42.24 68.24 0.16 0.17 0.28 0.69 -0.18 Covered/w/another[4703]
YMR317W Putative protein of unknown function with some similarity to sialidase from Trypanosoma; YMR317W is not an essential gene Uncharacterized chr13:907362-910784 907362-910784 87.7% 40.99 50.99 30.66 32.32 45.65 53.32 45.99 31.49 49.49 0.17 0.13 0.21 0.65 0.38 Frag>80[4704,4705,4706]
YMR316C-B "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr13:907319-907627 907319-907627 99.3% 74.94 117.30 81.46 55.39 91.23 84.71 96.12 68.42 87.97 0.35 0.28 0.36 0.36 1.06 Matched[4704]
YMR318C ADH6 NADPH-dependent medium chain alcohol dehydrogenase with broad substrate specificity; member of the cinnamyl family of alcohol dehydrogenases; may be involved in fusel alcohol synthesis or in aldehyde tolerance Verified chr13:911059-912141 911059-912141 98.9% 795.18 614.12 802.64 758.78 500.25 404.12 704.65 780.71 452.19 2.60 3.17 1.87 -0.79 -0.44 Frag>80[4706,4707,4708]
YMR319C FET4 Low-affinity Fe(II) transporter of the plasma membrane Verified chr13:912878-914536 912878-914536 99.2% 402.66 675.35 335.25 309.13 171.27 138.47 539.01 322.19 154.87 1.99 1.31 0.64 -1.06 -0.81 Matched[4709]
YMR320W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr13:916744-917049 916744-917049 99.1% 79.14 158.29 52.76 32.98 19.79 13.19 118.71 42.87 16.49 0.44 0.17 0.07 -1.38 -0.86 Covered[4710]
YMR321C Putative protein of unknown function Uncharacterized chr13:917577-917894 917577-917894 11.7% 26.88 53.75 0.00 26.88 53.75 0.00 40.31 13.44 26.88 0.15 0.05 0.11 1.00 -1.88 Overlap[4710]
YMR322C SNO4 "Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S. cerevisiae Hsp31p, Hsp32p, and Hsp33p; member of the DJ-1/ThiJ/PfpI superfamily; may have a role in pyridoxine metabolism" Uncharacterized chr13:918364-919077 918364-919077 3.7% 0.00 0.00 0.00 0.00 0.00 37.85 0.00 0.00 18.93 0.00 0.00 0.08 Inf 2.04
YMR323W ERR3 "Protein of unknown function, has similarity to enolases" Verified chr13:920086-921399 920086-921399 7.0% 0.00 0.00 0.00 0.00 21.61 10.81 0.00 0.00 16.21 0.00 0.00 0.07 Inf 3.62
YMR324C "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; transcription is AZF1 dependent in glycerol-lactate medium and SLT2 dependent in response to the lipid hydroperoxides" Dubious chr13:922200-922442 922200-922442 19.6% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN -0.03
YMR325W Hypothetical protein Uncharacterized chr13:922639-923013 922639-923013 5.7% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.58
YMR326C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the telomere on the right arm of chromosome 13" Dubious chr13:923492-923800 923492-923800 47.5% 0.00 6.81 0.00 0.00 0.00 6.81 3.41 0.00 3.41 0.01 0.00 0.01 Inf -0.02
YNL339W-B "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr14:734-1216 734-1216 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YNL339W-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr14:1517-2092 1517-2092 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YNL339C YRF1-6 "Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p" Verified chr14:371-6098 371-5931,6080-6098 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.20
YNL338W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps TEL14L-XC, which is Telomeric X element Core sequence on the left arm of Chromosome XIV" Dubious chr14:6561-6719 6561-6719 43.7% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN NaN
YNL337W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr14:7165-7419 7165-7419 2.1% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN -0.61
YNL336W COS1 "Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" Verified chr14:8330-9475 8330-9475 4.6% 438.44 209.69 209.69 266.88 476.57 362.19 324.07 238.28 419.38 1.20 0.97 1.74 0.82 0.17 Frag<80[4711,4712]
YNL335W Hypothetical protein Uncharacterized chr14:11452-12129 11452-12129 0.6% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.38
YNL334C SNO2 "Protein of unknown function, nearly identical to Sno3p; expression is induced before the diauxic shift and also in the absence of thiamin" Verified chr14:12208-12876 12208-12876 0.7% 206.90 0.00 0.00 0.00 0.00 0.00 103.45 0.00 0.00 0.38 0.00 0.00 NaN 0.56
YNL333W SNZ2 "Member of a stationary phase-induced gene family; transcription of SNZ2 is induced prior to diauxic shift, and also in the absence of thiamin in a Thi2p-dependent manner; forms a coregulated gene pair with SNO2; interacts with Thi11p" Verified chr14:13267-14163 13267-14163 5.2% 42.82 21.41 107.05 0.00 64.23 42.82 32.11 53.52 53.52 0.12 0.22 0.22 0.00 -0.19
YNL332W THI12 "Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP); member of a subtelomeric gene family including THI5, THI11, THI12, and THI13" Verified chr14:14832-15854 14832-15854 3.4% 0.00 0.00 0.00 28.99 28.99 0.00 0.00 14.49 14.49 0.00 0.06 0.06 0.00 0.86
YNL331C AAD14 Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role Verified chr14:16118-17248 16118-17248 46.8% 43.43 45.32 47.21 41.55 54.76 39.66 44.38 44.38 47.21 0.16 0.18 0.20 0.09 0.70 Frag<80[4713,4714,4715]
YNL330C RPD3 Histone deacetylase; regulates transcription and silencing Verified chr14:18001-19302 18001-19302 99.2% 296.52 318.97 307.35 283.35 404.13 287.23 307.74 295.35 345.68 1.14 1.20 1.43 0.23 0.43 Matched[4716]
YNL329C PEX6 AAA-peroxin that heterodimerizes with AAA-peroxin Pex6p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol Verified chr14:19541-22633 19541-22633 99.0% 78.70 93.72 69.88 59.76 69.88 45.72 86.21 64.82 57.80 0.32 0.26 0.24 -0.17 0.27 Covered/w/another[4717]
YNL328C MDJ2 Constituent of the mitochondrial import motor associated with the presequence translocase; function overlaps with that of Pam18p; stimulates the ATPase activity of Ssc1p to drive mitochondrial import; contains a J domain Verified chr14:22834-23274 22834-23274 98.9% 25.23 48.17 36.70 27.53 50.46 57.34 36.70 32.11 53.90 0.14 0.13 0.22 0.75 1.46 Covered/w/another[4717]
YNL327W EGT2 "Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase required for proper cell separation after cytokinesis, expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner" Verified chr14:24047-27172 24047-27172 94.6% 534.74 522.23 474.91 377.90 306.24 209.23 528.48 426.40 257.74 1.95 1.73 1.07 -0.73 -0.57 Matched[4718]
YNL326C PFA3 "Palmitoyltransferase for Vac8p, required for vacuolar membrane fusion; contains an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; autoacylates; required for vacuolar integrity under stress conditions" Verified chr14:27336-28346 27336-28346 99.1% 95.86 115.84 99.86 94.87 134.81 76.89 105.85 97.36 105.85 0.39 0.40 0.44 0.12 -0.09 Matched[4719]
YNL324W "Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr14:31049-31444 31049-31444 99.6% 10.14 25.36 17.75 20.29 12.68 25.36 17.75 19.02 19.02 0.07 0.08 0.08 0.00 0.09 Covered/w/another[4720]
YNL325C FIG4 "Protein that forms a complex with Vac14p and is involved in turnover of PI3,5P2 (phosphatidylinositol 3,5-bisphosphate) after hyperosmotic shock; required for efficient mating; member of a protein family with a domain homologous to Sac1p" Verified chr14:28738-31377 28738-31377 99.3% 30.14 41.96 33.57 31.66 47.30 27.85 36.05 32.62 37.58 0.13 0.13 0.16 0.20 0.02 Matched[4720]
YNL323W LEM3 "Membrane protein of the plasma membrane and ER, involved in translocation of phospholipids and alkylphosphocholine drugs across the plasma membrane" Verified chr14:31943-33187 31943-33187 98.6% 289.18 255.78 241.12 241.12 225.64 175.95 272.48 241.12 200.79 1.01 0.98 0.83 -0.26 -0.14 Matched[4721]
YNL322C KRE1 Cell wall glycoprotein involved in beta-glucan assembly; serves as a K1 killer toxin membrane receptor Verified chr14:33293-34234 33293-34234 98.1% 741.11 872.02 812.51 687.01 1402.15 1297.21 806.56 749.76 1349.68 2.98 3.04 5.59 0.85 0.82 Matched[4722]
YNL321W VNX1 Low affinity vacuolar membrane localized monovalent cation/H+ antiporter; member of the calcium exchanger (CAX) family; potential Cdc28p substrate Verified chr14:34695-37421 34695-37421 98.9% 130.83 162.70 138.61 131.94 163.81 206.43 146.76 135.27 185.12 0.54 0.55 0.77 0.45 0.97 Matched[4723]
YNL320W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr14:37699-38553 37699-38553 98.9% 153.74 191.58 147.83 149.01 273.18 163.20 172.66 148.42 218.19 0.64 0.60 0.90 0.56 0.46 Frag>80[4724,4725]
YNL319W Dubious open reading frame unlikely to encode a protein; partially overlaps the verified gene HXT14 Dubious chr14:38641-39081 38641-39081 99.4% 25.10 13.69 20.54 9.13 22.82 9.13 19.40 14.83 15.97 0.07 0.06 0.07 0.11 0.03 Frag<80[4725]
YNL318C HXT14 "Protein with similarity to hexose transporter family members, expression is induced in low glucose and repressed in high glucose; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr14:38706-40328 38706-40328 99.3% 4.34 3.72 1.24 0.00 3.10 4.96 4.03 0.62 4.03 0.01 0.00 0.02 2.70 0.97 Frag<80[4725]
YNL317W PFS2 Integral subunit of the pre-mRNA cleavage and polyadenylation factor (CPF) complex; plays an essential role in mRNA 3'-end formation by bridging different processing factors and thereby promoting the assembly of the processing complex Verified chr14:40618-42015 40618-42015 98.7% 89.12 102.16 103.61 94.92 106.51 93.47 95.64 99.27 99.99 0.35 0.40 0.41 0.01 0.41 Covered/w/another[4726]
YNL316C PHA2 "Prephenate dehydratase, catalyzes the conversion of prephanate to phenylpyruvate, which is a step in the phenylalanine biosynthesis pathway" Verified chr14:42070-43074 42070-43074 98.9% 85.53 75.47 92.58 66.42 94.59 60.38 80.50 79.50 77.48 0.30 0.32 0.32 -0.04 0.23 Covered/w/another[4726]
YNL315C ATP11 "Molecular chaperone, required for the assembly of alpha and beta subunits into the F1 sector of mitochondrial F1F0 ATP synthase" Verified chr14:43323-44279 43323-44279 99.0% 458.92 407.23 417.78 416.72 309.11 239.48 433.07 417.25 274.30 1.60 1.69 1.14 -0.61 -0.25 Matched[4727]
YNL314W DAL82 "Positive regulator of allophanate inducible genes; binds a dodecanucleotide sequence upstream of all genes that are induced by allophanate; contains an UISALL DNA-binding, a transcriptional activation, and a coiled-coil domain" Verified chr14:44446-45213 44446-45213 98.7% 72.59 84.47 65.99 68.63 125.38 69.95 78.53 67.31 97.66 0.29 0.27 0.40 0.54 1.07 Matched[4728]
YNL313C "Putative protein of unknown function; identified as interacting with Kar2p, Grs1p, and Tub3p in high-throughput TAP-tagging experiments; YNL313C is an essential gene" Uncharacterized chr14:45307-48021 45307-48021 99.0% 113.07 75.88 85.17 72.16 10.79 7.07 94.47 78.67 8.93 0.35 0.32 0.04 -3.14 -2.23 Matched[4729]
YNL312W RFA2 "Subunit of heterotrimeric Replication Protein A (RPA), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination" Verified chr14:48286-49215 48286-48292,48401-49215 98.7% 346.34 258.83 341.41 274.86 271.16 134.35 302.59 308.13 202.75 1.12 1.25 0.84 -0.60 -0.72 Matched[4730]
YNL311C "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; putative F-box protein; analysis of integrated high-throughput datasets predicts involvement in ubiquitin-dependent protein catabolism" Verified chr14:49396-51687 49396-51687 99.1% 79.22 89.78 69.10 58.98 35.65 26.85 84.50 64.04 31.25 0.31 0.26 0.13 -1.04 -0.76 Matched[4731]
YNL310C ZIM17 Heat shock protein with a zinc finger motif; essential for protein import into mitochondria; may act with Pam18p to facilitate recognition and folding of imported proteins by Ssc1p (mtHSP70) in the mitochondrial matrix Verified chr14:51906-52430 51906-52430 98.9% 215.80 240.85 198.46 163.78 337.19 227.36 228.32 181.12 282.27 0.84 0.74 1.17 0.64 0.72 Matched[4732]
YNL309W STB1 "Protein with a role in regulation of MBF-specific transcription at Start, phosphorylated by Cln-Cdc28p kinases in vitro; unphosphorylated form binds Swi6p and binding is required for Stb1p function; expression is cell-cycle regulated" Verified chr14:52661-53923 52661-53923 98.7% 78.64 81.85 95.49 53.76 52.16 38.52 80.25 74.63 45.34 0.30 0.30 0.19 -0.72 -0.20 Matched[4733]
YNL308C KRI1 Essential nucleolar protein required for 40S ribosome biogenesis; physically and functionally interacts with Krr1p Verified chr14:54121-55896 54121-55896 99.4% 542.17 292.90 367.11 273.07 49.85 34.56 417.53 320.09 42.21 1.54 1.30 0.17 -2.92 -1.84 Matched[4734]
YNL307C MCK1 Protein serine/threonine/tyrosine (dual-specificity) kinase involved in control of chromosome segregation and in regulating entry into meiosis; related to mammalian glycogen synthase kinases of the GSK-3 family Verified chr14:56446-57573 56446-57573 98.9% 790.68 724.34 745.85 735.10 603.32 520.84 757.51 740.48 562.08 2.80 3.01 2.33 -0.40 -0.04 Matched[4736]
YNL306W MRPS18 "Mitochondrial ribosomal protein of the small subunit; essential for viability, unlike most other mitoribosomal proteins" Verified chr14:58155-58808 58155-58808 98.4% 663.39 618.33 716.21 598.14 776.80 518.90 640.86 657.17 647.85 2.37 2.67 2.68 -0.02 0.22 Matched[4737]
YNL305C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YNL305C is not an essential gene Uncharacterized chr14:58898-59791 58898-59791 98.1% 232.54 370.48 299.80 330.58 1046.45 755.77 301.51 315.19 901.11 1.11 1.28 3.73 1.52 1.25 Matched[4738]
YNL304W YPT11 Rab-type small GTPase that interacts with the C-terminal tail domain of Myo2p to mediate distribution of mitochondria to daughter cells Verified chr14:60297-61550 60297-61550 98.5% 50.21 72.08 44.54 52.64 68.84 49.40 61.15 48.59 59.12 0.23 0.20 0.24 0.28 0.51 Matched[4739]
YNL303W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr14:61510-61857 61510-61857 99.5% 196.30 178.98 127.01 124.13 49.07 25.98 187.64 125.57 37.53 0.69 0.51 0.16 -1.74 0.59 Overlap[4739,4740]
YNL302C RPS19B "Protein component of the small (40S) ribosomal subunit, required for assembly and maturation of pre-40 S particles; mutations in human RPS19 are associated with Diamond Blackfan anemia; nearly identical to Rps19Ap" Verified chr14:61958-62943 61958-62372,62924-62943 61.3% 8028.75 7042.50 7477.50 6401.25 1890.00 1863.75 7535.62 6939.38 1876.88 27.82 28.17 7.78 -1.89 -2.62 Matched[4740]
YNL301C RPL18B "Protein component of the large (60S) ribosomal subunit, identical to Rpl18Ap and has similarity to rat L18 ribosomal protein" Verified chr14:63570-64562 63570-64018,64451-64562 45.5% 1268.93 908.62 963.45 618.80 477.81 238.90 1088.77 791.12 358.36 4.02 3.21 1.48 -1.14 -1.41 Matched[4741]
YNL300W "Glycosylphosphatidylinositol-dependent cell wall protein, expression is periodic and decreases in respone to ergosterol perturbation or upon entry into stationary phase; depletion increases resistance to lactic acid" Uncharacterized chr14:65744-66052 65744-66052 99.0% 1418.11 1094.62 1444.25 1094.62 169.91 65.35 1256.36 1269.43 117.63 4.64 5.15 0.49 -3.43 -3.44 Matched[4743]
YNL299W TRF5 "Poly (A) polymerase involved in nuclear RNA quality control based on: homology with Trf4p, genetic interactions with TRF4 mutants, physical interaction with Mtr4p (TRAMP subunit), and by direct assay; disputed role as a sigma DNA polymerase" Verified chr14:66517-68445 66517-68445 98.5% 81.58 56.31 31.05 33.16 10.53 6.32 68.94 32.10 8.42 0.25 0.13 0.03 -1.93 -1.13 Matched[4744]
YNL298W CLA4 "Cdc42p activated signal transducing kinase of the PAK (p21-activated kinase) family, involved in septin ring assembly and cytokinesis; directly phosphorylates septins Cdc3p and Cdc10p; other yeast PAK family members are Ste20p and Skm1p" Verified chr14:68915-71443 68915-71443 98.5% 112.75 114.36 109.54 92.29 54.97 60.19 113.55 100.91 57.58 0.42 0.41 0.24 -0.81 -0.30 Matched[4745]
YNL296W "Dubious open reading frame unlikely to encode a functional protein; deletion adversely affects sporulation; deletion mutant exhibits synthetic phenotype under expression of mutant huntingtin fragment, but gene does not have human ortholog" Dubious chr14:76273-76587 76273-76587 98.5% 12.89 22.56 22.56 32.23 35.46 41.90 17.73 27.40 38.68 0.07 0.11 0.16 0.50 NaN Covered/w/another[4746]
YNL297C MON2 "Peripheral membrane protein with a role in endocytosis and vacuole integrity, interacts with Arl1p and localizes to the endosome; member of the Sec7p family of proteins" Verified chr14:71673-76583 71673-76583 99.1% 109.50 123.67 99.02 104.36 92.04 102.31 116.58 101.69 97.17 0.43 0.41 0.40 -0.07 0.12 Matched[4746]
YNL295W Putative protein of unknown function Uncharacterized chr14:76946-78520 76946-78520 98.6% 59.86 66.29 48.27 53.42 72.73 64.36 63.07 50.85 68.55 0.23 0.21 0.28 0.43 0.43 Matched[4747]
YNL294C RIM21 "Component of the RIM101 pathway, has a role in cell wall construction and alkaline pH response; has similarity to A. nidulans PalH" Verified chr14:78659-80260 78659-80260 99.1% 153.04 172.56 145.48 131.00 231.13 141.07 162.80 138.24 186.10 0.60 0.56 0.77 0.43 0.64 Matched[4748]
YNL293W MSB3 "GTPase-activating protein for Sec4p and several other Rab GTPases, regulates exocytosis via its action on Sec4p, also required for proper actin organization; similar to Msb4p; both Msb3p and Msb4p localize to sites of polarized growth" Verified chr14:80640-82541 80640-82541 98.5% 72.04 70.44 70.97 61.36 193.70 130.20 71.24 66.17 161.95 0.26 0.27 0.67 1.29 1.01 Matched[4749]
YNL292W PUS4 "Pseudouridine synthase, catalyzes only the formation of pseudouridine-55 (Psi55), a highly conserved tRNA modification, in mitochondrial and cytoplasmic tRNAs; PUS4 overexpression leads to translational derepression of GCN4 (Gcd- phenotype)" Verified chr14:82806-84017 82806-84017 98.3% 193.83 155.23 164.46 141.80 52.02 36.92 174.53 153.13 44.47 0.64 0.62 0.18 -1.78 -1.33 Matched[4750]
YNL291C MID1 "N-glycosylated integral membrane protein of the ER membrane and plasma membrane, functions as a stretch-activated Ca2+-permeable cation channel required for Ca2+ influx stimulated by pheromone; interacts with Cch1p; forms an oligomer" Verified chr14:84169-85815 84169-85815 98.9% 187.21 190.90 177.39 138.72 108.64 92.07 189.05 158.06 100.36 0.70 0.64 0.42 -0.66 -0.61 Matched[4751]
YNL290W RFC3 "Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon" Verified chr14:86218-87240 86218-87240 98.2% 271.71 221.95 221.95 206.02 211.00 140.33 246.83 213.98 175.67 0.91 0.87 0.73 -0.28 0.03 Frag>80[4752,4753]
YNL289W PCL1 "Pho85 cyclin of the Pcl1,2-like subfamily, involved in entry into the mitotic cell cycle and regulation of morphogenesis, localizes to sites of polarized cell growth" Verified chr14:87897-88736 87897-88736 98.7% 342.62 353.47 285.92 196.64 65.15 16.89 348.04 241.28 41.02 1.28 0.98 0.17 -2.56 -2.47 Matched[4754]
YNL288W CAF40 "Evolutionarily conserved subunit of the CCR4-NOT complex involved in controlling mRNA initiation, elongation and degradation; binds Cdc39p" Verified chr14:90303-91424 90303-91424 98.8% 177.66 183.08 202.01 175.86 230.87 176.76 180.37 188.94 203.82 0.67 0.77 0.84 0.11 0.73 Matched[4756]
YNL287W SEC21 "Gamma subunit of coatomer, a heptameric protein complex that together with Arf1p forms the COPI coat; involved in ER to Golgi transport of selective cargo" Verified chr14:91994-94801 91994-94801 99.1% 591.78 554.39 576.68 578.83 460.55 511.60 573.08 577.75 486.08 2.12 2.35 2.01 -0.25 0.43 Frag>80[4757,4758]
YNL286W CUS2 "Protein that binds to U2 snRNA and Prp11p, may be involved in U2 snRNA folding; contains two RNA recognition motifs (RRMs)" Verified chr14:95223-96080 95223-96080 98.4% 139.77 136.22 112.53 127.92 226.24 86.47 137.99 120.23 156.35 0.51 0.49 0.65 0.38 -0.06 Matched[4759]
YNL285W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr14:96173-96544 96173-96544 60.0% 0.00 13.44 0.00 0.00 0.00 4.48 6.72 0.00 2.24 0.02 0.00 0.01 Inf 0.43
YNL284C MRPL10 Mitochondrial ribosomal protein of the large subunit; appears as two protein spots (YmL10 and YmL18) on two-dimensional SDS gels Verified chr14:103134-104102 103134-104102 99.2% 302.85 291.40 350.72 274.75 351.76 215.43 297.13 312.74 283.60 1.10 1.27 1.18 -0.14 -0.06 Frag>80[4760,4761]
YNL283C WSC2 Partially redundant sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway involved in maintenance of cell wall integrity and recovery from heat shock; secretory pathway Wsc2p is required for the arrest of secretion response Verified chr14:105184-106695 105184-106695 98.2% 291.07 294.44 330.15 264.12 201.46 146.21 292.76 297.14 173.83 1.08 1.21 0.72 -0.77 -0.31 Frag>80[4762,4763]
YNL282W POP3 "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends" Verified chr14:107687-108274 107687-108274 98.6% 77.63 87.98 55.20 72.45 24.15 39.68 82.80 63.83 31.91 0.31 0.26 0.13 -1.00 -1.14 Matched[4764]
YNL281W HCH1 Heat shock protein regulator that binds to Hsp90p and may stimulate ATPase activity; originally identified as a high-copy number suppressor of a HSP90 loss-of-function mutation; GFP-fusion protein localizes to the cytoplasm and nucleus Verified chr14:108467-108928 108467-108928 98.4% 521.31 490.51 464.12 354.14 5734.40 3673.36 505.91 409.13 4703.88 1.87 1.66 19.49 3.52 2.54 Matched[4765]
YNL280C ERG24 "C-14 sterol reductase, acts in ergosterol biosynthesis; mutants accumulate the abnormal sterol ignosterol (ergosta-8,14 dienol), and are viable under anaerobic growth conditions but inviable on rich medium under aerobic conditions" Verified chr14:109095-110411 109095-110411 99.0% 427.05 499.12 360.35 318.95 180.17 128.04 463.09 339.65 154.11 1.71 1.38 0.64 -1.14 -0.36 Matched[4766]
YNL279W PRM1 Pheromone-regulated multispanning membrane protein involved in membrane fusion during mating; predicted to have 5 transmembrane segments and a coiled coil domain; localizes to the shmoo tip; regulated by Ste12p Verified chr14:110917-112902 110917-112902 98.7% 33.65 36.71 45.89 26.01 32.12 14.28 35.18 35.95 23.20 0.13 0.15 0.10 -0.63 -2.34 Matched[4767]
YNL278W CAF120 "Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation" Verified chr14:113271-116453 113271-116453 98.7% 58.26 36.61 45.20 34.38 30.56 29.92 47.43 39.79 30.24 0.18 0.16 0.13 -0.40 0.43 Matched[4768]
YNL277W-A Putative protein of unknown function Uncharacterized chr14:116679-116867 116679-116867 98.9% 5.35 0.00 5.35 5.35 21.40 5.35 2.67 5.35 13.37 0.01 0.02 0.06 1.32 NaN Covered/w/another[4768]
YNL277W MET2 "L-homoserine-O-acetyltransferase, catalyzes the conversion of homoserine to O-acetyl homoserine which is the first step of the methionine biosynthetic pathway" Verified chr14:117349-118809 117349-118809 98.5% 57.67 111.17 68.09 50.03 68.09 51.42 84.42 59.06 59.76 0.31 0.24 0.25 0.02 0.20 Covered/w/another[4769]
YNL276C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene MET2/YNL277W" Dubious chr14:118431-118826 118431-118826 98.6% 28.18 71.72 56.35 28.18 84.53 56.35 49.95 42.26 70.44 0.18 0.17 0.29 0.74 0.19 Covered/w/another[4769]
YNL275W BOR1 "Boron efflux transporter of the plasma membrane; binds HCO3-, I-, Br-, NO3- and Cl-; has similarity to the characterized boron efflux transporter A. thaliana BOR1" Verified chr14:119268-120998 119268-120998 98.9% 51.39 48.47 63.65 46.13 40.29 25.69 49.93 54.89 32.99 0.18 0.22 0.14 -0.73 0.12 Covered/w/another[4769]
YNL274C GOR1 "Glyoxylate reductase; null mutation results in increased biomass after diauxic shift; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr14:121118-122170 121118-122170 99.1% 83.38 135.13 145.67 144.71 1834.29 1403.99 109.25 145.19 1619.14 0.40 0.59 6.71 3.48 3.08 Matched[4770]
YNL273W TOF1 "Subunit of a replication-pausing checkpoint complex (Tof1p-Mrc1p-Csm3p) that acts at the stalled replication fork to promote sister chromatid cohesion after DNA damage, facilitating gap repair of damaged DNA; interacts with the MCM helicase" Verified chr14:122883-126599 122883-126599 98.8% 75.16 64.54 64.81 51.47 23.69 23.42 69.85 58.14 23.55 0.26 0.24 0.10 -1.30 -0.78 Frag<80[4771]
YNL272C SEC2 "Guanyl-nucleotide exchange factor for the small G-protein Sec4p, located on cytoplasmic vesicles; essential for post-Golgi vesicle transport" Verified chr14:126805-129084 126805-129084 99.2% 148.07 144.54 148.96 135.25 127.74 85.31 146.30 142.10 106.52 0.54 0.58 0.44 -0.42 -0.55 Matched[4772]
YNL271C BNI1 "Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables, functionally redundant with BNR1" Verified chr14:129523-135384 129523-135384 99.1% 204.53 220.37 173.37 170.27 108.46 201.77 212.45 171.82 155.12 0.78 0.70 0.64 -0.15 0.58 Matched[4773]
YNL270C ALP1 Arginine transporter; expression is normally very low and it is unclear what conditions would induce significant expression Verified chr14:135941-137662 135941-137662 94.6% 7.37 4.91 8.59 3.68 13.51 12.89 6.14 6.14 13.20 0.02 0.02 0.05 1.10 -0.18 Overlap[4774]
YNL269W BSC4 "Protein of unknown function, ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression; readthrough is increased upon depletion of Sup35p" Verified chr14:137700-138095 137700-138095 99.1% 2.55 2.55 12.74 7.65 22.94 15.29 2.55 10.20 19.12 0.01 0.04 0.08 0.91 1.74 Matched[4774]
YNL268W LYP1 "Lysine permease; one of three amino acid permeases (Alp1p, Can1p, Lyp1p) responsible for uptake of cationic amino acids" Verified chr14:138551-140386 138551-140386 95.3% 601.60 582.75 505.05 439.34 318.80 269.09 592.17 472.20 293.94 2.19 1.92 1.22 -0.68 -0.34 Matched[4775]
YNL267W PIK1 "Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosphatidylinositol-4,5-biphosphate; may control cytokineses through the actin cytoskeleton" Verified chr14:140879-144079 140879-144079 98.7% 161.69 177.51 155.68 158.84 125.93 125.93 169.60 157.26 125.93 0.63 0.64 0.52 -0.32 0.08 Frag<80[4776]
YNL266W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF IST1/YNL265C" Dubious chr14:144246-144665 144246-144665 99.3% 261.29 294.85 316.42 345.19 491.41 337.99 278.07 330.80 414.70 1.03 1.34 1.72 0.33 -0.04 Covered/w/another[4777]
YNL265C IST1 "Putative translation initiation factor, as suggested by computational analysis of large-scale protein-protein interaction data" Verified chr14:144281-145282 144281-145150,145256-145282 99.4% 203.02 229.94 235.55 268.07 367.90 277.05 216.48 251.81 322.48 0.80 1.02 1.34 0.36 0.56 Covered/w/another[4777]
YNL264C PDR17 "Phosphatidylinositol transfer protein (PITP), downregulates Plb1p-mediated turnover of phosphatidylcholine, found in the cytosol and microsomes, homologous to Pdr16p, deletion affects phospholipid composition" Verified chr14:145564-146616 145564-146616 99.1% 242.44 288.44 202.20 194.53 264.48 210.82 265.44 198.36 237.65 0.98 0.81 0.98 0.26 0.81 Covered/w/another[4777]
YNL263C YIF1 "Integral membrane protein required for the fusion of ER-derived COPII transport vesicles with the Golgi; interacts with Yip1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles" Verified chr14:146897-147841 146897-147841 98.7% 276.49 336.50 323.64 275.42 317.21 251.84 306.50 299.53 284.53 1.13 1.22 1.18 -0.07 0.19 Frag>80[4778,4779]
YNL262W POL2 "Catalytic subunit of DNA polymerase (II) epsilon, one of the major chromosomal DNA replication polymerases characterized by processivity and proofreading exonuclease activity; also involved in DNA synthesis during DNA repair" Verified chr14:148213-154881 148213-154881 98.8% 126.61 109.00 102.17 101.11 35.68 46.91 117.81 101.64 41.29 0.43 0.41 0.17 -1.30 -0.66 Frag<80[4780]
YNL261W ORC5 "Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing" Verified chr14:155101-156540 155101-156540 99.0% 175.99 133.92 140.93 106.58 89.05 58.90 154.96 123.75 73.97 0.57 0.50 0.31 -0.74 -0.30 Covered/w/another[4781]
YNL260C Putative protein of unknown function with similarity to a human protein overexpressed in oral cancers; localizes to the nucleus and cytoplasm; YNL260C is an essential gene Uncharacterized chr14:156860-157456 156860-157456 99.5% 79.10 92.57 100.98 67.32 149.79 106.03 85.83 84.15 127.91 0.32 0.34 0.53 0.60 0.50 Covered/w/another[4781]
YNL259C ATX1 "Cytosolic copper metallochaperone that transports copper to the secretory vesicle copper transporter Ccc2p for eventual insertion into Fet3p, which is a multicopper oxidase required for high-affinity iron uptake" Verified chr14:157645-157866 157645-157866 99.3% 512.47 462.59 503.40 380.95 721.09 349.21 487.53 442.18 535.15 1.80 1.79 2.22 0.28 -1.01 Matched[4782]
YNL258C DSL1 "Endoplasmic reticulum (ER)-localized peripheral membrane protein required for Golgi-to-ER retrograde traffic; component of the ER target site that interacts with coatomer, the major component of the COPI vesicle protein coat" Verified chr14:158110-160374 158110-160374 99.3% 193.44 200.55 167.20 168.53 144.08 97.39 196.99 167.87 120.73 0.73 0.68 0.50 -0.48 -0.29 Matched[4783]
YNL257C SIP3 "Protein that activates transcription through interaction with DNA-bound Snf1p, C-terminal region has a putative leucine zipper motif; potential Cdc28p substrate" Verified chr14:160632-164321 160632-164321 99.2% 131.35 127.80 116.06 113.33 104.86 108.69 129.58 114.69 106.77 0.48 0.47 0.44 -0.10 0.09 Matched[4784]
YNL256W FOL1 "Multifunctional enzyme of the folic acid biosynthesis pathway, has dihydropteroate synthetase, dihydro-6-hydroxymethylpterin pyrophosphokinase, and dihydroneopterin aldolase activities" Verified chr14:164624-167098 164624-167098 98.8% 143.15 83.03 102.25 79.35 26.99 20.04 113.09 90.80 23.52 0.42 0.37 0.10 -1.95 -1.63 Matched[4785]
YNL255C GIS2 "Protein with seven cysteine-rich CCHC zinc-finger motifs, similar to human CNBP, proposed to be involved in the RAS/cAMP signaling pathway" Verified chr14:167330-167791 167330-167791 99.3% 2448.85 1650.74 2019.26 1757.59 586.59 488.46 2049.79 1888.42 537.53 7.57 7.67 2.23 -1.81 -1.97 Matched[4786]
YNL254C Hypothetical protein Uncharacterized chr14:168044-169249 168044-169249 99.0% 58.60 62.79 41.86 30.97 8.37 9.21 60.69 36.42 8.79 0.22 0.15 0.04 -2.05 -1.47 Frag<80[4787]
YNL253W TEX1 "Protein involved in mRNA export, component of the transcription export (TREX) complex" Verified chr14:170019-171287 170019-171287 98.9% 102.78 69.31 83.65 68.52 55.77 31.87 86.04 76.09 43.82 0.32 0.31 0.18 -0.80 -0.49 Matched[4788]
YNL252C MRPL17 Mitochondrial ribosomal protein of the large subunit Verified chr14:171442-172287 171442-172287 99.2% 264.54 266.92 320.54 289.56 358.67 253.81 265.73 305.05 306.24 0.98 1.24 1.27 0.01 0.09 Matched[4789]
YNL251C NRD1 "RNA-binding protein that interacts with the C-terminal domain of the RNA polymerase II large subunit (Rpo21p), required for transcription termination and 3' end maturation of nonpolyadenylated RNAs" Verified chr14:172589-174316 172589-174316 98.8% 246.65 198.02 259.54 113.66 60.34 65.62 222.34 186.60 62.98 0.82 0.76 0.26 -1.57 -0.54 Matched[4790]
YNL250W RAD50 "Subunit of MRX complex, with Mre11p and Xrs2p, involved in processing double-strand DNA breaks in vegetative cells, initiation of meiotic DSBs, telomere maintenance, and nonhomologous end joining" Verified chr14:175411-179349 175411-179349 98.7% 48.33 42.93 40.11 38.56 50.90 44.48 45.63 39.33 47.69 0.17 0.16 0.20 0.28 0.65 Covered/w/another[4791]
YNL249C MPA43 "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr14:179395-181023 179395-181023 99.3% 72.35 71.11 53.18 40.81 54.42 26.59 71.73 47.00 40.50 0.26 0.19 0.17 -0.21 -0.96 Covered/w/another[4791]
YNL248C RPA49 RNA polymerase I subunit A49 Verified chr14:181362-182609 181362-182609 99.0% 502.82 280.96 302.01 259.10 28.34 4.05 391.89 280.56 16.19 1.45 1.14 0.07 -4.11 -4.59 Covered/w/another[4791]
YNL247W "Essential protein of unknown function; may interact with ribosomes, based on co-purification experiments" Verified chr14:182876-185179 182876-185179 98.8% 587.21 471.26 550.75 552.95 141.86 157.67 529.23 551.85 149.77 1.95 2.24 0.62 -1.88 -0.57 Matched[4792]
YNL246W VPS75 NAP family histone chaperone; binds to histone H3-H4 tetramers and to histone acetyltransferase RTT109; possesses nucleosome assembly activity in vitro; proposed role in vacuolar protein sorting Verified chr14:185461-186350 185461-185492,185588-186350 98.0% 359.30 332.35 356.73 293.86 341.34 237.40 345.83 325.30 289.37 1.28 1.32 1.20 -0.17 -0.05 Matched[4793]
YNL245C CWC25 "Component of a complex containing Cef1p, involved in pre-mRNA splicing; has similarity to S. pombe Cwf25p" Verified chr14:186347-186886 186347-186886 99.3% 227.51 238.69 195.80 160.37 208.86 130.54 233.10 178.09 169.70 0.86 0.72 0.70 -0.07 -0.04 Frag<80[4794]
YNL244C SUI1 Translation initiation factor eIF1; component of a complex involved in recognition of the initiator codon; modulates translation accuracy at the initiation phase Verified chr14:187171-187497 187171-187497 99.3% 3132.44 2704.31 2849.08 3000.00 2189.94 1549.28 2918.38 2924.54 1869.61 10.77 11.87 7.75 -0.65 -1.01 Matched[4795]
YNL243W SLA2 Transmembrane actin-binding protein involved in membrane cytoskeleton assembly and cell polarization; adaptor protein that links actin to clathrin and endocytosis; present in the actin cortical patch of the emerging bud tip; dimer in vivo Verified chr14:188052-190958 188052-190958 98.5% 301.09 323.79 350.69 315.76 332.52 342.30 312.44 333.22 337.41 1.15 1.35 1.40 0.02 0.62 Frag>80[4796,4797]
YNL242W ATG2 Peripheral membrane protein required for the formation of cytosolic sequestering vesicles involved in vacuolar import through both the Cvt pathway and autophagy; interacts with Atg9p and is necessary for its trafficking Verified chr14:191325-196103 191325-196103 98.9% 31.11 45.08 41.69 45.93 58.63 90.59 38.10 43.81 74.61 0.14 0.18 0.31 0.77 1.01 Matched[4798]
YNL241C ZWF1 "Glucose-6-phosphate dehydrogenase (G6PD), catalyzes the first step of the pentose phosphate pathway; involved in adapting to oxidatve stress; homolog of the human G6PD which is deficient in patients with hemolytic anemia" Verified chr14:196427-197944 196427-197944 98.7% 433.17 403.80 537.96 501.92 1079.93 770.23 418.49 519.94 925.08 1.54 2.11 3.83 0.83 1.05 Matched[4799]
YNL240C NAR1 "Nuclear architecture related protein; component of the cytosolic iron-sulfur (FeS) protein assembly machinery, required for maturation of cytosolic and nuclear FeS proteins; homologous to human Narf" Verified chr14:198503-199978 198503-199978 98.6% 89.34 91.40 74.91 52.23 61.85 41.92 90.37 63.57 51.88 0.33 0.26 0.21 -0.29 -0.11 Matched[4800]
YNL239W LAP3 Cysteine aminopeptidase with homocysteine-thiolactonase activity; protects cells against homocysteine toxicity; has bleomycin hydrolase activity in vitro; transcription is regulated by galactose via Gal4p; orthologous to human BLMH Verified chr14:200570-201934 200570-201934 98.9% 427.43 568.18 465.21 445.95 585.96 628.19 497.81 455.58 607.07 1.84 1.85 2.52 0.41 1.05 Matched[4802]
YNL238W KEX2 "Subtilisin-like protease (proprotein convertase), a calcium-dependent serine protease involved in the activation of proproteins of the secretory pathway" Verified chr14:202429-204873 202429-204873 98.7% 213.50 213.92 204.80 165.83 162.93 157.95 213.71 185.31 160.44 0.79 0.75 0.66 -0.21 0.42 Matched[4803]
YNL237W YTP1 "Probable type-III integral membrane protein of unknown function, has regions of similarity to mitochondrial electron transport proteins" Verified chr14:205189-206568 205189-206568 98.6% 76.44 85.26 81.59 64.68 149.21 124.22 80.85 73.13 136.71 0.30 0.30 0.57 0.90 1.55 Matched[4804]
YNL236W SIN4 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; contributes to both postive and negative transcriptional regulation; dispensible for basal transcription Verified chr14:206931-209855 206931-209855 99.0% 104.59 100.45 104.25 84.23 74.91 79.05 102.52 94.24 76.98 0.38 0.38 0.32 -0.29 -0.01 Matched[4805]
YNL235C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF SIN4/YNL236W, a subunit of the mediator complex" Dubious chr14:209549-209980 209549-209980 98.9% 126.41 140.46 119.39 95.98 105.35 60.87 133.44 107.69 83.11 0.49 0.44 0.34 -0.37 -0.21 Covered/w/another[4805]
YNL234W Similar to globins and has a functional heme-binding domain; involved in glucose signaling or metabolism; regulated by Rgt1p Uncharacterized chr14:210234-211514 210234-211514 98.9% 46.55 32.35 28.40 27.61 40.24 14.20 39.45 28.01 27.22 0.15 0.11 0.11 -0.04 0.67
YNL233W BNI4 "Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, required for localization of chitin synthase III to the bud neck via interaction with the chitin synthase III regulatory subunit Skt5p" Verified chr14:211923-214601 211923-214601 98.7% 117.61 99.08 97.95 94.92 67.31 61.26 108.35 96.43 64.29 0.40 0.39 0.27 -0.58 0.18 Covered/w/another[4806]
YNL232W CSL4 "Subunit of the exosome, which is an essential complex present in both nucleus and cytoplasm that mediates RNA processing and degradation" Verified chr14:214924-215802 214924-215802 98.2% 182.99 159.83 141.30 118.14 52.12 41.69 171.41 129.72 46.91 0.63 0.53 0.19 -1.47 -0.60 Covered/w/another[4806]
YNL231C PDR16 "Phosphatidylinositol transfer protein (PITP) controlled by the multiple drug resistance regulator Pdr1p, localizes to lipid particles and microsomes, controls levels of various lipids, may regulate lipid synthesis, homologous to Pdr17p" Verified chr14:215988-217043 215988-217043 99.2% 640.42 523.98 582.20 498.21 490.58 252.92 582.20 540.21 371.75 2.15 2.19 1.54 -0.54 -0.59 Matched[4807]
YNL230C ELA1 "Elongin A, F-box protein that forms a heterodimer with Elc1p and is required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21; subunit of the Elongin-Cullin-Socs (ECS) ligase complex" Verified chr14:217524-218663 217524-218663 99.0% 81.54 86.86 61.15 51.41 85.97 49.63 84.20 56.28 67.80 0.31 0.23 0.28 0.27 0.68 Matched[4808]
YNL229C URE2 Nitrogen catabolite repression transcriptional regulator that acts by inhibition of GLN3 transcription in good nitrogen source; altered form of Ure2p creates [URE3] prion Verified chr14:219138-220202 219138-220202 99.2% 309.38 300.86 262.07 245.99 236.53 168.41 305.12 254.03 202.47 1.13 1.03 0.84 -0.33 -0.20 Frag>80[4809,4810,4811]
YNL228W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; almost completely overlaps ORF YNL227C/JJJ1" Dubious chr14:220646-221422 220646-221422 99.4% 179.97 130.77 117.82 89.34 37.55 53.09 155.37 103.58 45.32 0.57 0.42 0.19 -1.19 -0.45 Frag<80[4811]
YNL226W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene JJJ1/YNL227C" Dubious chr14:222240-222650 222240-222650 99.2% 39.22 29.42 22.06 36.77 2.45 9.81 34.32 29.42 6.13 0.13 0.12 0.03 -2.26 -0.32 Overlap[4812,4813]
YNL227C JJJ1 "Co-chaperone that stimulates the ATPase activity of Ssa1p, required for a late step of ribosome biogenesis; associated with the cytosolic large ribosomal subunit; contains a J-domain; mutation causes defects in fluid-phase endocytosis" Verified chr14:220660-222432 220660-222432 99.4% 136.71 107.78 93.03 72.04 23.26 31.77 122.24 82.54 27.51 0.45 0.34 0.11 -1.58 -1.85 Frag>80[4811,4812]
YNL225C CNM67 Component of the spindle pole body outer plaque; required for spindle orientation and mitotic nuclear migration Verified chr14:222725-224470 222725-224470 99.3% 109.58 96.89 92.28 78.44 107.27 66.32 103.23 85.36 86.80 0.38 0.35 0.36 0.02 0.16 Matched[4813]
YNL224C SQS1 Protein of unknown function; overexpression antagonizes the suppression of splicing defects by spp382 mutants; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus Verified chr14:224797-227100 224797-227100 99.3% 114.98 108.42 100.99 108.86 112.80 98.81 111.70 104.93 105.80 0.41 0.43 0.44 0.01 0.18 Matched[4814]
YNL223W ATG4 Cysteine protease required for autophagy; cleaves Atg8p to a form required for autophagosome and Cvt vesicle generation; mediates attachment of autophagosomes to microtubules through interactions with Tub1p and Tub2p Verified chr14:227371-228855 227371-228855 98.5% 60.84 82.03 49.22 54.00 99.80 71.09 71.43 51.61 85.45 0.26 0.21 0.35 0.73 0.33 Covered/w/another[4815]
YNL222W SSU72 Transcription/RNA-processing factor that associates with TFIIB and cleavage/polyadenylation factor Pta1p; exhibits phosphatase activity on serine-5 of the RNA polymerase II C-terminal domain; affects start site selection in vivo Verified chr14:229095-229715 229095-229715 98.9% 118.84 105.81 128.60 97.67 149.77 78.14 112.32 113.14 113.95 0.41 0.46 0.47 0.01 -0.32 Covered/w/another[4815]
YNL221C POP1 "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; binds to the RPR1 RNA subunit in RNase P" Verified chr14:231069-233696 231069-233696 99.2% 159.65 161.95 117.82 89.04 40.68 31.09 160.80 103.43 35.88 0.59 0.42 0.15 -1.53 -0.74 Matched[4817]
YNL220W ADE12 "Adenylosuccinate synthase, catalyzes the first step in synthesis of adenosine monophosphate from inosine 5'monophosphate during purine nucleotide biosynthesis; exhibits binding to single-stranded autonomously replicating (ARS) core sequence" Verified chr14:234414-235715 234414-235715 98.7% 1945.92 1899.24 2024.51 1770.86 553.20 334.57 1922.58 1897.69 443.88 7.10 7.70 1.84 -2.10 -1.63 Matched[4818]
YNL219C ALG9 "Mannosyltransferase, involved in N-linked glycosylation; catalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides; mutation of the human ortholog causes type 1 congenital disorders of glycosylation" Verified chr14:235997-237664 235997-237664 99.0% 293.01 306.33 271.82 274.85 197.36 180.41 299.67 273.33 188.88 1.11 1.11 0.78 -0.53 0.13 Frag>80[4819,4820]
YNL218W MGS1 Protein with DNA-dependent ATPase and ssDNA annealing activities involved in maintenance of genome; interacts functionally with DNA polymerase delta; homolog of human Werner helicase interacting protein (WHIP) Verified chr14:238239-240002 238239-240002 98.5% 74.24 54.10 56.98 37.98 36.83 22.45 64.17 47.48 29.64 0.24 0.19 0.12 -0.68 -0.02 Matched[4821]
YNL217W Hypothetical protein Uncharacterized chr14:240332-241312 240332-241312 98.7% 585.44 549.30 478.06 395.46 169.33 71.24 567.37 436.76 120.29 2.09 1.77 0.50 -1.86 -2.32 Matched[4822]
YNL216W RAP1 "DNA-binding protein involved in either activation or repression of transcription, depending on binding site context; also binds telomere sequences and plays a role in telomeric position effect (silencing) and telomere structure" Verified chr14:241690-244173 241690-244173 98.7% 160.78 176.28 159.55 135.07 79.57 95.49 168.53 147.31 87.53 0.62 0.60 0.36 -0.75 0.15 Matched[4823]
YNL215W IES2 Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions Verified chr14:244469-245431 244469-245431 97.8% 190.02 190.02 203.82 161.36 323.78 195.33 190.02 182.59 259.55 0.70 0.74 1.08 0.51 0.40 Frag>80[4824,4825]
YNL214W PEX17 Peroxisomal membrane peroxin and subunit of the docking complex that facilitates the import of peroxisomal matrix proteins; required for peroxisome biogenesis Verified chr14:245618-246217 245618-246217 98.8% 75.93 75.93 84.36 67.49 182.23 87.74 75.93 75.93 134.98 0.28 0.31 0.56 0.83 0.60 Covered/w/another[4826]
YNL213C "Protein of unknown function; null mutant lacks mitochondrial DNA and cannot grow on glycerol; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr14:246461-247105 246461-247105 99.2% 186.02 161.01 154.76 143.82 165.70 96.92 173.52 149.29 131.31 0.64 0.61 0.54 -0.19 -0.12 Covered/w/another[4826]
YNL212W VID27 "Cytoplasmic protein of unknown function; possibly involved in vacuolar protein degradation; not essential for proteasome-dependent degradation of fructose-1,6-bisphosphatase (FBPase); null mutants exhibit normal growth" Verified chr14:247462-249810 247462-249810 98.7% 159.64 125.56 154.46 126.85 169.13 103.12 142.60 140.66 136.13 0.53 0.57 0.56 -0.05 0.15 Frag>80[4827,4828]
YNL211C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YNL211C is not an essential gene Uncharacterized chr14:250056-250316 250056-250316 99.2% 104.26 177.63 73.37 127.43 193.08 73.37 140.95 100.40 133.23 0.52 0.41 0.55 0.41 -0.07 Matched[4828]
YNL210W MER1 Protein with RNA-binding motifs required for meiosis-specific mRNA splicing; required for chromosome pairing and meiotic recombination Verified chr14:250932-251744 250932-251744 98.9% 26.12 39.81 21.15 6.22 11.20 7.46 32.97 13.68 9.33 0.12 0.06 0.04 -0.55 -0.15
YNL209W SSB2 "Cytoplasmic ATPase that is a ribosome-associated molecular chaperone, functions with J-protein partner Zuo1p; may be involved in the folding of newly-synthesized polypeptide chains; member of the HSP70 family; homolog of SSB1" Verified chr14:252060-253901 252060-253901 23.2% 5389.95 3728.09 4700.43 4485.39 558.63 628.75 4559.02 4592.91 593.69 16.83 18.64 2.46 -2.95 -3.32 Frag<80[4829,4830,4831]
YNL208W "Protein of unknown function; may interact with ribosomes, based on co-purification experiments; authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies; potential orthologs found in other fungi" Verified chr14:254419-255018 254419-255018 95.2% 2172.27 2487.35 2667.64 2266.79 5358.03 3553.35 2329.81 2467.22 4455.69 8.60 10.01 18.46 0.85 0.48 Frag>80[4832,4833]
YNL207W RIO2 Essential serine kinase involved in the processing of the 20S pre-rRNA into mature 18S rRNA; has similarity to Rio1p Verified chr14:255354-256631 255354-256631 98.6% 179.34 123.79 100.78 97.61 27.77 15.08 151.57 99.19 21.43 0.56 0.40 0.09 -2.21 -2.19 Matched[4834]
YNL206C RTT106 Protein with a role in regulation of Ty1 transposition Verified chr14:256789-258156 256789-258156 99.3% 240.83 225.37 201.80 198.12 134.04 85.43 233.10 199.96 109.74 0.86 0.81 0.45 -0.87 -0.83 Matched[4835]
YNL205C "Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr14:258156-258578 258156-258578 99.0% 26.27 28.66 4.78 7.16 21.49 4.78 27.47 5.97 13.14 0.10 0.02 0.05 1.14 0.12 Overlap[4835]
YNL204C SPS18 "Protein of unknown function, contains a putative zinc-binding domain; expressed during sporulation" Verified chr14:258376-259278 258376-259278 99.3% 26.76 31.22 25.64 12.26 24.53 8.92 28.99 18.95 16.72 0.11 0.08 0.07 -0.18 0.34 Overlap[4836]
YNL202W SPS19 "Peroxisomal 2,4-dienoyl-CoA reductase, auxiliary enzyme of fatty acid beta-oxidation; homodimeric enzyme required for growth and sporulation on petroselineate medium; expression induced during late sporulation and in the presence of oleate" Verified chr14:259579-260457 259579-260457 98.4% 43.95 27.76 40.48 40.48 87.91 38.17 35.86 40.48 63.04 0.13 0.16 0.26 0.64 1.10 Matched[4836]
YNL203C Dubious open reading frame unlikely to encode a functional protein; based on available experimental and comparative sequence data Dubious chr14:259440-260051 259440-260051 98.4% 41.50 14.94 43.16 38.18 79.67 29.88 28.22 40.67 54.78 0.10 0.17 0.23 0.43 0.58 Matched[4836]
YNL201C PSY2 Putative subunit of an evolutionarily conserved protein phosphatase complex containing the catalytic subunit Pph3p and the regulatory subunit Psy4p; required for cisplatin and oxaliplatin resistance; localizes to nucleus Verified chr14:260628-263204 260628-263204 99.3% 121.14 113.32 96.13 85.58 67.21 52.75 117.23 90.85 59.98 0.43 0.37 0.25 -0.60 -0.34 Matched[4837]
YNL200C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr14:263714-264454 263714-264454 98.8% 241.82 535.55 356.58 347.01 1482.32 1185.86 388.68 351.80 1334.09 1.43 1.43 5.53 1.92 1.95 Frag>80[4838,4839,4840]
YNL199C GCR2 Transcriptional activator of genes involved in glycolysis; interacts and functions with the DNA-binding protein Gcr1p Verified chr14:264927-266531 264927-266531 99.2% 158.83 160.72 137.49 133.09 147.53 130.58 159.77 135.29 139.06 0.59 0.55 0.58 0.04 0.23 Frag>80[4840,4841]
YNL198C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr14:266515-266817 266515-266817 98.8% 53.42 13.36 53.42 46.74 36.73 23.37 33.39 50.08 30.05 0.12 0.20 0.12 -0.74 1.00 Overlap[4841]
YNL197C WHI3 RNA binding protein that sequesters CLN3 mRNA in cytoplasmic foci; cytoplasmic retention factor for Cdc28p and associated cyclins; regulates cell fate and dose-dependently regulates the critical cell size required for passage through Start Verified chr14:267609-269594 267609-269594 98.7% 319.76 269.78 294.26 263.66 177.48 221.33 294.77 278.96 199.41 1.09 1.13 0.83 -0.48 0.22 Frag>80[4842,4843]
YNL196C SLZ1 Sporulation-specific protein with a leucine zipper motif Uncharacterized chr14:270276-271172 270276-271172 99.3% 23.58 30.31 33.68 23.58 69.61 42.66 26.94 28.63 56.14 0.10 0.12 0.23 0.97 2.00 Frag>80[4844,4845]
YNL195C "Putative protein of unknown function; shares a promoter with YNL194C; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr14:271524-272309 271524-272309 98.6% 19.36 33.55 15.49 18.07 664.62 363.93 26.46 16.78 514.28 0.10 0.07 2.13 4.94 3.65 Covered/w/another[4846]
YNL194C Integral membrane protein localized to eisosomes; sporulation and plasma membrane sphingolipid content are altered in mutants; has homologs SUR7 and FMP45; GFP-fusion protein is induced in response to the DNA-damaging agent MMS Verified chr14:272711-273616 272711-273616 98.5% 23.52 24.64 21.28 16.80 1525.62 1196.30 24.08 19.04 1360.96 0.09 0.08 5.64 6.16 5.02 Covered/w/another[4846]
YNL193W Putative protein of unknown function; exhibits a two-hybrid interaction with Yhr151cp in a large-scale analysis Uncharacterized chr14:274369-276045 274369-276045 98.9% 91.02 75.34 73.54 72.93 162.74 93.43 83.18 73.24 128.09 0.31 0.30 0.53 0.81 1.00 Matched[4847]
YNL192W CHS1 "Chitin synthase I, requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for repairing the chitin septum during cytokinesis; transcription activated by mating factor" Verified chr14:276503-279898 276503-279898 98.9% 229.19 207.16 194.66 169.36 223.53 177.40 218.18 182.01 200.47 0.81 0.74 0.83 0.14 0.24 Matched[4848]
YNL191W DUG3 "Probable glutamine amidotransferase, forms a complex with Dug1p and Dug2p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)" Verified chr14:280433-281506 280433-281506 98.6% 89.71 151.09 69.88 64.21 81.21 71.77 120.40 67.04 76.49 0.44 0.27 0.32 0.19 0.59 Matched[4849]
YNL190W Cell wall protein of unknown function; proposed role as a hydrophilin induced by osmotic stress; contains a putative GPI-attachment site Uncharacterized chr14:282396-283010 282396-283010 61.9% 4459.92 4436.27 3802.89 3461.24 2260.18 1968.46 4448.09 3632.06 2114.32 16.42 14.74 8.76 -0.78 -1.81 Matched[4850]
YNL189W SRP1 "Karyopherin alpha homolog, forms a dimer with karyopherin beta Kap95p to mediate import of nuclear proteins, binds the nuclear localization signal of the substrate during import; may also play a role in regulation of protein degradation" Verified chr14:284261-285889 284261-285889 98.8% 547.36 410.68 522.51 469.70 397.01 321.83 479.02 496.10 359.42 1.77 2.01 1.49 -0.46 0.10 Matched[4852]
YNL188W KAR1 "Essential protein involved in karyogamy during mating and in spindle pole body duplication during mitosis, localizes to the half-bridge of the spindle pole body, interacts with Spc72p during karyogamy, also interacts with Cdc31p" Verified chr14:286309-287610 286309-287610 98.8% 188.93 140.72 140.72 119.73 87.08 45.09 164.83 130.23 66.09 0.61 0.53 0.27 -0.98 -0.72 Frag>80[4853,4854]
YNL187W Putative protein of unknown function; contains a consensus nuclear export signal (NES) sequence similar to the consensus sequence recognized by Crm1p; may interact with or be fuctionally redundant with Prp40p Uncharacterized chr14:287996-289069 287996-289069 98.5% 52.95 86.99 42.55 55.79 72.81 52.01 69.97 49.17 62.41 0.26 0.20 0.26 0.34 0.78 Covered/w/another[4855]
YNL186W UBP10 Ubiquitin-specific protease that deubiquitinates ubiquitin-protein moieties; may regulate silencing by acting on Sir4p; involved in posttranscriptionally regulating Gap1p and possibly other transporters; primarily located in the nucleus Verified chr14:289500-291878 289500-291878 96.9% 320.92 224.64 208.16 135.31 63.32 49.01 272.78 171.74 56.16 1.01 0.70 0.23 -1.61 -1.31 Covered/w/another[4855]
YNL185C MRPL19 Mitochondrial ribosomal protein of the large subunit Verified chr14:292195-292671 292195-292671 99.1% 325.72 289.77 340.53 296.11 365.91 266.50 307.75 318.32 316.21 1.14 1.29 1.31 -0.01 -0.07 Matched[4856]
YNL184C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr14:292559-292885 292559-292885 98.9% 151.51 126.77 157.69 170.06 151.51 129.86 139.14 163.88 140.69 0.51 0.67 0.58 -0.22 -1.14 Frag<80[4856]
YNL183C NPR1 Protein kinase that stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation Verified chr14:293139-295511 293139-295511 98.8% 119.84 123.68 110.04 109.18 145.43 103.64 121.76 109.61 124.54 0.45 0.44 0.52 0.18 0.63 Matched[4857]
YNL182C IPI3 "Essential component of the Rix1 complex (Rix1p, Ipi1p, Ipi3p) that is required for processing of ITS2 sequences from 35S pre-rRNA; highly conserved and contains WD40 motifs; Rix1 complex associates with Mdn1p in pre-60S ribosomal particles" Verified chr14:295962-297629 295962-297629 99.2% 160.18 84.02 98.53 63.47 12.09 4.84 122.10 81.00 8.46 0.45 0.33 0.04 -3.26 -3.07 Matched[4858]
YNL181W Putative oxidoreductase; required for cell viability Uncharacterized chr14:298337-299560 298337-299560 98.5% 293.65 220.66 224.80 192.45 165.08 112.82 257.15 208.63 138.95 0.95 0.85 0.58 -0.59 -0.41 Matched[4859]
YNL180C RHO5 "Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely involved in protein kinase C (Pkc1p)-dependent signal transduction pathway that controls cell integrity" Verified chr14:299656-300651 299656-300651 99.2% 363.51 388.83 387.82 349.34 446.54 378.70 376.17 368.58 412.62 1.39 1.50 1.71 0.16 0.46 Matched[4860]
YNL179C "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; deletion in cyr1 mutant results in loss of stress resistance" Dubious chr14:300668-301105 300668-301105 96.1% 144.99 144.99 118.85 111.72 114.09 128.35 144.99 115.28 121.22 0.54 0.47 0.50 0.07 -0.55 Frag<80[4861]
YNL178W RPS3 "Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins" Verified chr14:302682-303404 302682-303404 98.5% 13687.82 9905.14 12062.46 9512.13 2749.63 1611.32 11796.48 10787.30 2180.48 43.55 43.79 9.03 -2.31 -2.99 Matched[4863]
YNL177C MRPL22 Mitochondrial ribosomal protein of the large subunit Verified chr14:303688-304617 303688-304617 99.3% 296.74 318.40 310.82 347.64 406.12 239.34 307.57 329.23 322.73 1.14 1.34 1.34 -0.03 -0.51 Frag>80[4864,4865]
YNL176C "Cell cycle-regulated gene of unknown function, promoter bound by Fkh2p" Uncharacterized chr14:305072-306982 305072-306982 98.5% 223.67 216.77 211.99 173.73 174.26 181.17 220.22 192.86 177.72 0.81 0.78 0.74 -0.12 0.36 Matched[4866]
YNL174W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene NOP13/YNL175C" Dubious chr14:308076-308648 308076-308648 99.2% 346.42 154.75 209.26 218.05 28.14 10.55 250.59 213.66 19.34 0.93 0.87 0.08 -3.47 -0.44 Matched[4867]
YNL175C NOP13 "Protein of unknown function, localizes to the nucleolus and nucleoplasm; contains an RNA recognition motif (RRM) and has similarity to Nop12p, which is required for processing of pre-18S rRNA" Verified chr14:307403-308614 307403-308614 99.2% 398.31 178.78 257.78 202.07 24.11 10.81 288.55 229.92 17.46 1.07 0.93 0.07 -3.72 -3.55 Matched[4867]
YNL173C MDG1 Plasma membrane protein involved in G-protein mediated pheromone signaling pathway; overproduction suppresses bem1 mutations Verified chr14:308959-310059 308959-310059 99.3% 288.21 337.62 512.37 525.18 815.22 654.19 312.91 518.78 734.70 1.16 2.11 3.04 0.50 0.45 Frag>80[4868,4869]
YNL172W APC1 "Largest subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" Verified chr14:310638-315884 310638-315884 98.9% 38.55 35.47 34.70 32.00 38.75 44.53 37.01 33.35 41.64 0.14 0.14 0.17 0.32 0.49 Frag<80[4870]
YNL170W Dubious open reading frame unlikely to encode a functional protein; based on available experimental and comparative sequence data Dubious chr14:315980-316375 315980-316375 99.4% 210.77 266.64 253.94 266.64 246.32 185.38 238.70 260.29 215.85 0.88 1.06 0.89 -0.27 -0.01
YNL171C Dubious open reading frame unlikely to encode a functional protein; based on available experimental and comparative sequence data Dubious chr14:315631-315999 315631-315999 98.9% 128.72 112.29 106.81 95.86 134.20 112.29 120.51 101.34 123.25 0.44 0.41 0.51 0.28 0.04 Covered[4870]
YNL169C PSD1 "Phosphatidylserine decarboxylase of the mitochondrial inner membrane, converts phosphatidylserine to phosphatidylethanolamine" Verified chr14:316171-317673 316171-317673 98.9% 219.94 231.37 260.96 275.09 236.08 219.94 225.65 268.03 228.01 0.83 1.09 0.94 -0.23 0.32 Covered/w/another[4871]
YNL168C "Putative protein of unknown function; GFP-fusion protein is induced in response to the DNA-damaging agent MMS; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr14:318032-318811 318032-318811 98.9% 263.11 247.56 247.56 269.59 336.99 255.33 255.33 258.57 296.16 0.94 1.05 1.23 0.20 0.53 Covered/w/another[4871]
YNL167C SKO1 "Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, forms a complex with Tup1p and Ssn6p to both activate and repress transcription; cytosolic and nuclear protein involved in osmotic and oxidative stress responses" Verified chr14:319418-321361 319418-321361 98.9% 184.14 178.94 188.82 176.34 231.47 255.40 181.54 182.58 243.44 0.67 0.74 1.01 0.42 0.89 Covered/w/another[4871]
YNL166C BNI5 "Protein involved in organization of septins at the mother-bud neck, may interact directly with the Cdc11p septin, localizes to bud neck in a septin-dependent manner" Verified chr14:322221-323567 322221-323567 99.2% 255.18 211.03 219.26 188.58 136.20 107.76 233.11 203.92 121.98 0.86 0.83 0.51 -0.74 -0.48 Frag>80[4872,4873]
YNL165W Putative protein of unknown function; YNL165W is not an essential gene Uncharacterized chr14:323834-325054 323834-325054 98.8% 82.06 64.65 54.71 41.45 67.97 56.37 73.36 48.08 62.17 0.27 0.20 0.26 0.37 0.82 Covered/w/another[4874]
YNL164C IBD2 "Component of the BUB2-dependent spindle checkpoint pathway, interacts with Bfa1p and functions upstream of Bub2p and Bfa1p" Verified chr14:325267-326322 325267-326322 99.3% 76.32 81.09 51.52 37.21 25.76 13.36 78.71 44.36 19.56 0.29 0.18 0.08 -1.18 -1.88 Covered/w/another[4874]
YNL163C RIA1 Cytoplasmic GTPase involved in biogenesis of the 60S ribosome; has similarity to translation elongation factor 2 (Eft1p and Eft2p) Verified chr14:326743-330075 326743-330075 99.2% 137.02 111.31 105.87 85.60 47.19 43.25 124.17 95.73 45.22 0.46 0.39 0.19 -1.08 -0.47 Matched[4875]
YNL162W-A "Putative protein of unknown function, identified by homology" Uncharacterized chr14:330331-330549 330331-330549 99.3% 55.17 59.77 45.98 9.20 13.79 0.00 57.47 27.59 6.90 0.21 0.11 0.03 -2.00 -3.50 Matched[4876]
YNL162W RPL42A "Protein component of the large (60S) ribosomal subunit, identical to Rpl42Bp and has similarity to rat L44 ribosomal protein" Verified chr14:331324-332156 331324-331327,331840-332156 29.1% 6513.37 4524.06 5411.76 4449.20 1133.69 951.87 5518.72 4930.48 1042.78 20.37 20.01 4.32 -2.24 -3.20 Frag>80[4877,4878]
YNL161W CBK1 "Serine/threonine protein kinase that regulates cell morphogenesis pathways; involved in cell wall biosynthesis, apical growth, proper mating projection morphology, bipolar bud site selection in diploid cells, and cell separation" Verified chr14:332599-334869 332599-334869 98.3% 153.58 132.99 145.53 120.90 99.40 66.72 143.29 133.21 83.06 0.53 0.54 0.34 -0.68 -0.34 Matched[4879]
YNL160W YGP1 Cell wall-related secretory glycoprotein; induced by nutrient deprivation-associated growth arrest and upon entry into stationary phase; may be involved in adaptation prior to stationary phase entry; has similarity to Sps100p Verified chr14:336547-337611 336547-337611 99.2% 412.67 2360.53 576.41 552.75 4640.61 4368.97 1386.60 564.58 4504.79 5.12 2.29 18.66 3.00 2.82 Matched[4881]
YNL159C ASI2 Integral inner nuclear membrane protein that acts with Asi1p and Asi3p to ensure the fidelity of SPS-sensor signalling by maintaining the dormant repressed state of gene expression in the absence of inducing signals Verified chr14:338480-339349 338480-339349 99.1% 121.76 219.17 111.33 125.24 316.58 200.62 170.47 118.28 258.60 0.63 0.48 1.07 1.13 1.07 Matched[4883]
YNL158W PGA1 Essential protein required for maturation of Gas1p and Pho8p; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery; has synthetic genetic interations with secretory pathway genes Verified chr14:339614-340210 339614-340210 99.0% 126.89 147.20 121.82 113.36 145.51 116.74 137.05 117.59 131.12 0.51 0.48 0.54 0.16 0.71 Matched[4884]
YNL157W Hypothetical protein Uncharacterized chr14:340354-340860 340354-340860 98.7% 401.80 409.80 379.81 327.84 805.60 443.78 405.80 353.82 624.69 1.50 1.44 2.59 0.82 0.66 Matched[4885]
YNL156C NSG2 "Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; homolog of mammalian INSIG proteins" Verified chr14:341071-341970 341071-341970 98.9% 338.04 327.94 417.78 377.35 1007.39 624.43 332.99 397.57 815.91 1.23 1.61 3.38 1.04 1.10 Matched[4886]
YNL155W "Putative protein of unknown function, contains DHHC domain, also predicted to have thiol-disulfide oxidoreductase active site" Uncharacterized chr14:342518-343342 342518-343342 98.7% 433.51 327.89 405.26 361.05 1402.45 768.77 380.70 383.16 1085.61 1.41 1.56 4.50 1.50 0.94 Frag>80[4887,4888]
YNL154C YCK2 "Palmitoylated, plasma membrane-bound casein kinase I isoform; shares redundant functions with Yck1p in morphogenesis, proper septin assembly, endocytic trafficking; provides an essential function overlapping with that of Yck1p" Verified chr14:343638-345278 343638-345278 99.1% 547.34 546.73 539.35 473.54 432.34 332.09 547.03 506.44 382.22 2.02 2.06 1.58 -0.41 -0.09 Covered/w/another[4889]
YNL153C GIM3 Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it Verified chr14:345671-346060 345671-346060 99.2% 511.74 496.23 444.54 467.80 346.33 196.42 503.98 456.17 271.38 1.86 1.85 1.12 -0.75 -1.13 Covered/w/another[4889]
YNL152W Putative protein of unknown function; cytoplasmically localized protein proposed to function in phospholipid binding; YBL107C is an essential gene Uncharacterized chr14:346315-347544 346315-347544 98.8% 108.58 94.60 104.47 85.55 101.18 61.69 101.59 95.01 81.44 0.38 0.39 0.34 -0.22 0.31 Covered/w/another[4890]
YNL151C RPC31 RNA polymerase III subunit C31; contains HMG-like C-terminal domain Verified chr14:347768-348523 347768-348523 99.4% 356.52 234.13 255.42 198.22 37.25 21.28 295.33 226.82 29.27 1.09 0.92 0.12 -2.95 -2.84 Covered/w/another[4890]
YNL150W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; extensive overlap with PGA2/YNL149C, an uncharacterized gene with a proposed role in protein trafficking" Dubious chr14:349253-349660 349253-349660 99.4% 589.21 505.39 443.76 387.06 352.54 197.23 547.30 415.41 274.88 2.02 1.69 1.14 -0.60 -0.60 Matched[4891]
YNL149C PGA2 Essential protein required for maturation of Gas1p and Pho8p; involved in protein trafficking; GFP-fusion protein localizes to the ER and YFP-fusion protein to the nuclear envelope-ER network; null mutants have a cell separation defect Uncharacterized chr14:349369-349758 349369-349758 99.5% 659.79 520.62 484.54 402.06 432.99 201.03 590.21 443.30 317.01 2.18 1.80 1.31 -0.48 -1.41 Matched[4891]
YNL148C ALF1 "Alpha-tubulin folding protein, similar to mammalian cofactor B; Alf1p-GFP localizes to cytoplasmic microtubules; required for the folding of alpha-tubulin and may play an additional role in microtubule maintenance" Verified chr14:349909-350673 349909-350673 99.0% 124.12 153.17 117.52 105.63 62.06 30.37 138.64 111.58 46.21 0.51 0.45 0.19 -1.27 -1.14 Matched[4892]
YNL147W LSM7 "Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA" Verified chr14:350942-351385 350942-350959,351056-351385 99.0% 609.28 548.36 562.86 551.26 661.51 310.44 578.82 557.06 485.98 2.14 2.26 2.01 -0.20 -0.52 Matched[4893]
YNL146C-A Putative protein of unknown function Uncharacterized chr14:351388-351582 351388-351582 98.7% 109.07 166.20 83.10 72.71 129.84 72.71 137.63 77.91 101.28 0.51 0.32 0.42 0.38 NaN Matched[4894]
YNL146W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YNL146W is not an essential gene Uncharacterized chr14:351717-352019 351717-352019 99.4% 63.11 59.78 39.86 46.50 139.50 43.18 61.44 43.18 91.34 0.23 0.18 0.38 1.08 0.54 Matched[4894]
YNL145W MFA2 "Mating pheromone a-factor, made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA1" Verified chr14:352416-352532 352416-352532 98.8% 7841.33 8923.19 7685.54 6750.81 4465.92 1644.43 8382.26 7218.18 3055.18 30.94 29.30 12.66 -1.24 -1.77 Matched[4895]
YNL144W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YNL144C" Dubious chr14:353063-353146 353063-353146 99.6% 107.62 95.67 155.46 119.58 155.46 155.46 101.64 137.52 155.46 0.38 0.56 0.64 0.18 NaN Covered/w/another[4896]
YNL144C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YNL144C is not an essential gene" Uncharacterized chr14:352822-355044 352822-355044 99.0% 62.71 91.34 94.97 80.43 84.52 69.07 77.03 87.70 76.80 0.28 0.36 0.32 -0.19 0.12 Matched[4896]
YNL143C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr14:356796-357188 356796-357188 95.4% 39.99 42.66 45.32 31.99 74.65 31.99 41.32 38.66 53.32 0.15 0.16 0.22 0.46 0.62 Frag<80[4898]
YNL142W MEP2 Ammonium permease involved in regulation of pseudohyphal growth; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation Verified chr14:357455-358954 357455-358954 98.7% 66.18 83.74 71.59 66.86 39.84 31.74 74.96 69.22 35.79 0.28 0.28 0.15 -0.95 -0.84 Matched[4899]
YNL141W AAH1 "Adenine deaminase (adenine aminohydrolase), involved in purine salvage and nitrogen catabolism" Verified chr14:359598-360641 359598-360641 98.9% 500.52 316.58 305.93 182.98 47.44 20.33 408.55 244.45 33.88 1.51 0.99 0.14 -2.85 -2.99 Matched[4900]
YNL140C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene RLR1/YNL139C" Dubious chr14:360919-361488 360919-361488 99.2% 253.00 224.70 180.46 201.70 139.77 99.08 238.85 191.08 119.43 0.88 0.78 0.49 -0.68 -0.26 Covered/w/another[4901]
YNL139C RLR1 "Subunit of the THO complex, which is required for efficient transcription elongation and involved in transcriptional elongation-associated recombination; required for LacZ RNA expression from certain plasmids" Verified chr14:360926-365719 360926-365719 99.2% 96.76 96.34 78.25 78.67 45.64 63.73 96.55 78.46 54.69 0.36 0.32 0.23 -0.52 -0.01 Matched[4901]
YNL138W-A YSF3 "Component of the U2 snRNP, associated with the SF3b complex; conserved in Ashbya gossypii" Verified chr14:366035-366414 366035-366037,366160-366414 98.4% 157.51 137.82 149.63 114.19 208.70 141.76 147.66 131.91 175.23 0.55 0.54 0.73 0.41 NaN Covered/w/another[4902]
YNL138W SRV2 "CAP (cyclase-associated protein) subunit of adenylyl cyclase complex; N-terminus binds adenylyl cyclase and facilitates activation by RAS; C-terminus binds ADP-actin monomers, facilitating regulation of actin dynamics and cell morphogenesis" Verified chr14:366743-368323 366743-368323 98.8% 812.53 833.66 790.12 822.77 976.44 879.76 823.09 806.45 928.10 3.04 3.27 3.85 0.20 0.37 Matched[4902]
YNL137C NAM9 Mitochondrial ribosomal component of the small subunit Verified chr14:368597-370057 368597-370057 99.2% 288.98 271.74 291.05 292.43 242.08 168.29 280.36 291.74 205.18 1.03 1.18 0.85 -0.51 -0.23 Matched[4903]
YNL136W EAF7 "Subunit of the NuA4 histone acetyltransferase complex, which acetylates the N-terminal tails of histones H4 and H2A" Verified chr14:370370-371647 370370-371647 98.0% 206.09 259.61 200.50 192.51 216.48 177.33 232.85 196.51 196.90 0.86 0.80 0.82 0.00 0.13 Matched[4904]
YNL135C FPR1 "Peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin; also binds to the nonhistone chromatin binding protein Hmo1p and may regulate its assembly or function" Verified chr14:371884-372228 371884-372228 98.6% 4436.60 4424.84 4492.47 4160.24 6224.18 4436.60 4430.72 4326.35 5330.39 16.36 17.56 22.09 0.30 -0.46 Matched[4905]
YNL134C Putative protein of unknown function with similarity to dehydrogenases from other model organisms; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus and is induced by the DNA-damaging agent MMS Uncharacterized chr14:372453-373583 372453-373583 98.8% 713.23 414.33 840.30 587.94 1787.99 1659.12 563.78 714.12 1723.55 2.08 2.90 7.14 1.27 1.63 Matched[4906]
YNL133C FYV6 "Protein of unknown function, required for survival upon exposure to K1 killer toxin; proposed to regulate double-strand break repair via non-homologous end-joining" Verified chr14:374173-374694 374173-374694 99.5% 111.68 107.83 103.98 98.20 173.30 78.95 109.76 101.09 126.12 0.41 0.41 0.52 0.32 0.34 Matched[4908]
YNL132W KRE33 Essential protein of unknown function; heterozygous mutant shows haploinsufficiency in K1 killer toxin resistance Verified chr14:375323-378493 375323-378493 98.8% 227.84 125.09 148.70 130.51 15.32 6.06 176.46 139.61 10.69 0.65 0.57 0.04 -3.71 -3.21 Matched[4909]
YNL131W TOM22 Component of the TOM (translocase of outer membrane) complex responsible for initial import of mitochondrially directed proteins; acts as a receptor for precursor proteins and mediates interaction between the TOM and TIM complexes Verified chr14:378769-379227 378769-379227 98.7% 1246.90 1065.93 1266.76 1085.79 1129.93 924.69 1156.41 1176.28 1027.31 4.27 4.77 4.26 -0.20 -0.10 Matched[4910]
YNL130C CPT1 "Cholinephosphotransferase, required for phosphatidylcholine biosynthesis and for inositol-dependent regulation of EPT1 transcription" Verified chr14:379560-380833 379560-380691,380784-380833 98.8% 333.81 317.55 336.38 300.43 640.23 501.57 325.68 318.40 570.90 1.20 1.29 2.37 0.84 0.35 Matched[4911]
YNL130C-A Putative protein of unknown function Uncharacterized chr14:381247-381393 381247-381393 98.8% 27.55 27.55 20.67 0.00 55.11 41.33 27.55 10.33 48.22 0.10 0.04 0.20 2.22 NaN Covered/w/another[4912]
YNL129W NRK1 "Nicotinamide riboside kinase, catalyzes the synthesis of nicotinamide nucleotide (NMN) from nicotinamide riboside; involved in a salvage pathway for NAD+ biosynthesis" Verified chr14:381482-382204 381482-382204 98.8% 229.62 250.63 176.42 184.82 267.43 200.22 240.13 180.62 233.83 0.89 0.73 0.97 0.37 -0.12 Matched[4912]
YNL128W TEP1 Homolog of human tumor suppressor gene PTEN/MMAC1/TEP1 that has lipid phosphatase activity and is linked to the phosphatidylinositol signaling pathway; plays a role in normal sporulation Verified chr14:382361-383665 382361-383665 98.7% 10.87 13.20 10.87 10.09 16.30 19.40 12.03 10.48 17.85 0.04 0.04 0.07 0.77 0.54 Frag<80[4913]
YNL127W FAR11 "Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway different from the Far1p-dependent pathway; interacts with Far3p, Far7p, Far8p, Far9p, and Far10p" Verified chr14:383989-386850 383989-386850 98.8% 65.76 69.65 69.65 58.34 112.43 110.67 67.71 64.00 111.55 0.25 0.26 0.46 0.80 0.95 Covered/w/another[4914]
YNL126W SPC98 Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque Verified chr14:387229-389769 387229-389769 99.1% 90.93 77.83 81.00 63.14 46.06 25.81 84.38 72.07 35.94 0.31 0.29 0.15 -1.00 -0.99 Covered/w/another[4914]
YNL125C ESBP6 "Protein with similarity to monocarboxylate permeases, appears not to be involved in transport of monocarboxylates such as lactate, pyruvate or acetate across the plasma membrane" Verified chr14:390148-392169 390148-392169 98.5% 119.47 164.15 152.10 145.58 407.61 424.68 141.81 148.84 416.15 0.52 0.60 1.72 1.48 1.82 Covered/w/another[4914]
YNL124W NAF1 "Protein required for the assembly of box H/ACA snoRNPs and for pre-rRNA processing, forms a complex with Shq1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; has similarity to Gar1p and other RNA-binding proteins" Verified chr14:392894-394372 392894-394372 98.6% 140.63 110.44 102.90 58.31 89.18 76.83 125.54 80.60 83.00 0.46 0.33 0.34 0.04 0.45 Covered/w/another[4914]
YNL123W NMA111 Protein of unknown function which may contribute to lipid homeostasis and/or apoptosis; sequence similarity to the mammalian Omi/HtrA2 family of serine proteases Verified chr14:394687-397680 394687-397680 98.9% 218.21 145.92 168.21 159.43 78.37 60.12 182.06 163.82 69.25 0.67 0.66 0.29 -1.24 -0.67 Covered/w/another[4914]
YNL122C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YNL122C is not an essential gene Uncharacterized chr14:398025-398372 398025-398372 99.4% 237.08 202.39 306.47 254.43 410.55 251.54 219.73 280.45 331.04 0.81 1.14 1.37 0.24 0.15 Covered/w/another[4914]
YNL121C TOM70 Component (70 kDa) of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; acts as a receptor for incoming precursor proteins Verified chr14:398686-400539 398686-400539 99.2% 739.98 728.01 736.17 754.66 458.88 408.32 733.99 745.41 433.60 2.71 3.03 1.80 -0.78 -0.31 Frag>80[4915,4916]
YNL119W NCS2 "Protein with a role in urmylation and in invasive and pseudohyphal growth; inhibits replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts" Uncharacterized chr14:401042-402523 401042-402523 99.1% 109.61 85.78 66.04 46.98 14.30 6.13 97.70 56.51 10.21 0.36 0.23 0.04 -2.47 -1.82 Matched[4917]
YNL120C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; deletion enhances replication of Brome mosaic virus in S. cerevisiae, but likely due to effects on the overlapping gene" Dubious chr14:401035-401520 401035-401520 99.1% 66.44 64.36 45.67 22.84 4.15 6.23 65.40 34.26 5.19 0.24 0.14 0.02 -2.72 0.01 Covered/w/another[4917]
YNL118C DCP2 "Catalytic subunit of the Dcp1p-Dcp2p decapping enzyme complex, which removes the 5' cap structure from mRNAs prior to their degradation; member of the Nudix hydrolase family" Verified chr14:402654-405566 402654-405566 99.2% 264.50 285.97 251.69 227.46 307.09 277.31 275.24 239.58 292.20 1.02 0.97 1.21 0.29 0.69 Matched[4918]
YNL117W MLS1 "Malate synthase, enzyme of the glyoxylate cycle, involved in utilization of non-fermentable carbon sources; expression is subject to carbon catabolite repression; localizes in peroxisomes during growth in oleic acid medium" Verified chr14:406360-408024 406360-408024 98.6% 6.09 12.79 10.35 9.74 18.27 10.35 9.44 10.05 14.31 0.03 0.04 0.06 0.51 0.73
YNL116W DMA2 "Protein involved in regulating spindle position and orientation, functionally redundant with Dma1p; homolog of S. pombe Dma1 and H. sapiens Chfr" Verified chr14:408343-409911 408343-409911 98.7% 94.28 120.76 77.49 63.29 61.99 59.41 107.52 70.39 60.70 0.40 0.29 0.25 -0.21 0.29 Matched[4919]
YNL115C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YNL115C is not an essential gene Uncharacterized chr14:410121-412055 410121-412055 99.2% 132.89 206.89 154.26 157.38 354.37 332.49 169.89 155.82 343.43 0.63 0.63 1.42 1.14 1.23 Matched[4920]
YNL113W RPC19 "RNA polymerase subunit, common to RNA polymerases I and III" Verified chr14:412773-413201 412773-413201 98.3% 523.85 315.26 384.00 272.59 75.85 49.78 419.56 328.30 62.81 1.55 1.33 0.26 -2.39 -2.85 Matched[4921]
YNL114C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified ORF RPC19/YNL113W, an RNA polymerase subunit" Dubious chr14:412686-413057 412686-413057 98.3% 443.18 251.68 320.07 259.89 49.24 41.03 347.43 289.98 45.14 1.28 1.18 0.19 -2.68 -0.91 Matched[4921]
YNL112W DBP2 "Essential ATP-dependent RNA helicase of the DEAD-box protein family, involved in nonsense-mediated mRNA decay and rRNA processing" Verified chr14:413641-416283 413641-414913,415916-416283 98.4% 663.07 266.84 305.22 241.45 40.86 34.05 464.96 273.34 37.46 1.72 1.11 0.16 -2.87 -1.79 Covered/w/another[4922]
YNL111C CYB5 "Cytochrome b5, involved in the sterol and lipid biosynthesis pathways; required for sterol C5-6 and fatty acid desaturation" Verified chr14:416942-417304 416942-417304 99.4% 291.03 446.24 254.99 199.56 58.21 41.58 368.63 227.28 49.89 1.36 0.92 0.21 -2.19 -1.76 Covered/w/another[4922]
YNL110C NOP15 "Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis; localizes to both nucleolus and cytoplasm" Verified chr14:417828-418490 417828-418490 99.5% 571.32 342.49 386.44 306.12 33.34 4.55 456.90 346.28 18.94 1.69 1.41 0.08 -4.19 -4.46 Covered/w/another[4922]
YNL109W Hypothetical protein Dubious chr14:418966-419511 418966-419511 99.1% 282.68 225.40 253.12 212.47 177.37 134.87 254.04 232.79 156.12 0.94 0.94 0.65 -0.58 1.21 Matched[4923]
YNL108C Putative protein of unknown function with similarity to Tfc7p and prokaryotic phosphotransfer enzymes; null mutant shows alterations in glucose metabolism; GFP-fusion protein localizes to the cytoplasm and nucleus Uncharacterized chr14:419016-419828 419016-419828 99.1% 245.85 207.36 234.67 173.83 161.42 120.44 226.60 204.25 140.93 0.84 0.83 0.58 -0.54 -0.29 Matched[4923]
YNL107W YAF9 "Subunit of both the NuA4 histone H4 acetyltransferase complex and the SWR1 complex, may function to antagonize silencing near telomeres; interacts directly with Swc4p, has homology to human leukemogenic protein AF9, contains a YEATS domain" Verified chr14:420100-420780 420100-420780 98.7% 105.65 83.33 102.68 96.73 101.19 66.96 94.49 99.70 84.08 0.35 0.40 0.35 -0.25 -0.12 Covered/w/another[4924]
YNL105W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene INP52" Dubious chr14:424157-424585 424157-424585 99.4% 25.81 44.57 37.54 25.81 35.19 28.15 35.19 31.67 31.67 0.13 0.13 0.13 0.00 -0.02 Covered/w/another[4924]
YNL106C INP52 "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in endocytosis; hyperosmotic stress causes translocation to actin patches" Verified chr14:420946-424497 420946-424497 99.0% 46.90 67.65 55.71 49.46 46.05 38.94 57.27 52.58 42.49 0.21 0.21 0.18 -0.31 0.16 Covered/w/another[4924]
YNL103W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene MET4/YNL104C" Dubious chr14:426721-426810 426721-426810 99.3% 257.46 671.64 436.57 391.79 223.88 279.85 464.55 414.18 251.87 1.71 1.68 1.04 -0.72 NaN Covered/w/another[4925]
YNL104C LEU4 Alpha-isopropylmalate synthase (2-isopropylmalate synthase); the main isozyme responsible for the first step in the leucine biosynthesis pathway Verified chr14:424897-426756 424897-426756 89.9% 684.45 1098.47 778.38 744.88 507.95 485.22 891.46 761.63 496.58 3.29 3.09 2.06 -0.62 -0.06 Matched[4925]
YNL103W MET4 "Lecine-zipper transcriptional activator, responsible for the regulation of the sulfur amino acid pathway, requires different combinations of the auxiliary factors Cbf1p, Met28p, Met31p and Met32p" Verified chr14:427737-429755 427737-429755 98.8% 186.98 210.04 163.92 148.88 138.36 125.32 198.51 156.40 131.84 0.73 0.63 0.55 -0.25 0.19 Matched[4926]
YNL102W POL1 "Catalytic subunit of the DNA polymerase I alpha-primase complex, required for the initiation of DNA replication during mitotic DNA synthesis and premeiotic DNA synthesis" Verified chr14:430089-434495 430089-434495 98.7% 137.72 108.52 109.44 98.40 25.75 18.62 123.12 103.92 22.19 0.45 0.42 0.09 -2.23 -1.68 Matched[4927]
YNL101W AVT4 "Vacuolar transporter, exports large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters" Verified chr14:435001-437142 435001-437142 99.0% 119.73 130.57 98.05 107.00 107.00 99.46 125.15 102.52 103.23 0.46 0.42 0.43 0.01 0.30 Matched[4928]
YNL100W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YNL100W is not an essential gene" Uncharacterized chr14:437615-438319 437615-438319 98.8% 195.34 248.49 271.47 270.03 555.87 334.67 221.92 270.75 445.27 0.82 1.10 1.84 0.72 0.57 Covered/w/another[4929]
YNL099C OCA1 "Putative protein tyrosine phosphatase, required for cell cycle arrest in response to oxidative damage of DNA" Verified chr14:438569-439285 438569-439285 99.0% 314.20 318.42 356.46 286.02 333.92 252.20 316.31 321.24 293.06 1.17 1.30 1.21 -0.13 -0.05 Covered/w/another[4929]
YNL098C RAS2 "GTP-binding protein that regulates the nitrogen starvation response, sporulation, and filamentous growth; farnesylation and palmitoylation required for activity and localization to plasma membrane; homolog of mammalian Ras proto-oncogenes" Verified chr14:439604-440572 439604-440572 99.1% 844.46 881.95 1061.04 898.61 1929.45 1282.83 863.20 979.83 1606.14 3.19 3.98 6.65 0.71 0.77 Matched[4930]
YNL097C-B Putative protein of unknown function Uncharacterized chr14:440799-440921 440799-440921 99.5% 73.57 49.05 98.09 40.87 57.22 24.52 61.31 69.48 40.87 0.23 0.28 0.17 -0.77 NaN Matched[4931]
YNL097W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene PHO23/YNL097C" Dubious chr14:441433-441588 441433-441588 99.0% 116.50 122.98 84.14 84.14 155.34 135.92 119.74 84.14 145.63 0.44 0.34 0.60 0.79 NaN Covered/w/another[4932]
YNL097C PHO23 "Probable component of the Rpd3 histone deacetylase complex, involved in transcriptional regulation of PHO5; C-terminus has similarity to human candidate tumor suppressor p33(ING1)" Verified chr14:441368-442360 441368-442360 98.9% 105.85 77.35 94.66 79.39 154.71 101.78 91.60 87.02 128.24 0.34 0.35 0.53 0.56 0.38 Matched[4932]
YNL096C RPS7B "Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Ap; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins" Verified chr14:443400-444317 443400-443828,444174-444317 80.9% 3956.11 3319.42 3164.03 2348.20 1102.88 638.85 3637.77 2756.12 870.86 13.43 11.19 3.61 -1.66 -1.68 Matched[4933]
YNL095C Putative protein of unknown function predicted to contain a transmembrane domain; YNL095C is not an essential gene Uncharacterized chr14:444914-446842 444914-446842 98.9% 76.52 95.91 53.98 35.64 53.46 36.69 86.22 44.81 45.07 0.32 0.18 0.19 0.01 0.41 Matched[4934]
YNL094W APP1 "Protein of unknown function, interacts with Rvs161p and Rvs167p; computational analysis of protein-protein interactions in large-scale studies suggests a possible role in actin filament organization" Verified chr14:447613-449376 447613-449376 98.8% 157.18 218.56 139.97 134.81 158.32 124.48 187.87 137.39 141.40 0.69 0.56 0.59 0.04 0.36 Matched[4935]
YNL093W YPT53 "GTPase, similar to Ypt51p and Ypt52p and to mammalian rab5; required for vacuolar protein sorting and endocytosis" Verified chr14:449870-450532 449870-450532 98.5% 12.25 33.68 10.71 12.25 111.74 88.78 22.96 11.48 100.26 0.08 0.05 0.42 3.13 3.40 Covered/w/another[4937]
YNL092W Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; YNL092W is not an essential gene Uncharacterized chr14:450873-452075 450873-452075 98.8% 20.20 37.87 36.19 34.51 134.66 111.10 29.04 35.35 122.88 0.11 0.14 0.51 1.80 2.02 Covered/w/another[4937]
YNL091W NST1 "Protein of unknown function, mediates sensitivity to salt stress; interacts physically with the splicing factor Msl1p and also displays genetic interaction with MSL1" Verified chr14:452410-456132 452410-456132 98.5% 373.73 354.92 324.11 330.66 325.75 397.71 364.32 327.39 361.73 1.34 1.33 1.50 0.14 0.78 Frag>80[4938,4939]
YNL090W RHO2 "Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, involved in the establishment of cell polarity and in microtubule assembly" Verified chr14:456567-457145 456567-457145 98.6% 306.61 243.54 317.13 224.27 350.42 210.25 275.08 270.70 280.33 1.02 1.10 1.16 0.05 -0.21 Matched[4940]
YNL089C Dubious open reading frame unlikely to encode a functional protein; almost completely overlaps YNL090W/RHO2 which encodes a small GTPase of the Rho/Rac subfamily of Ras-like proteins Dubious chr14:456695-457171 456695-457171 98.4% 319.49 259.85 330.14 236.42 366.35 215.12 289.67 283.28 290.73 1.07 1.15 1.20 0.04 0.13 Matched[4940]
YNL088W TOP2 "Essential type II topoisomerase, relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone of both positively and negatively supercoiled DNA; cleaves complementary strands; localizes to axial cores in meiosis" Verified chr14:457706-461992 457706-461992 98.6% 236.27 185.66 197.96 206.24 123.22 158.22 210.97 202.10 140.72 0.78 0.82 0.58 -0.52 0.14 Matched[4941]
YNL087W TCB2 Bud-specific protein with a potential role in membrane trafficking; GFP-fusion protein migrates from the cell surface to intracellular vesicles near vacuole; contains 3 calcium and lipid binding domains; mRNA is targeted to the bud Verified chr14:462413-465949 462413-465949 98.8% 218.38 197.20 200.63 190.33 55.81 54.38 207.79 195.48 55.10 0.77 0.79 0.23 -1.83 -1.06 Matched[4942]
YNL086W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to endosomes Uncharacterized chr14:466336-466644 466336-466644 98.9% 98.21 98.21 68.75 58.93 124.40 94.94 98.21 63.84 109.67 0.36 0.26 0.45 0.78 0.53 Covered/w/another[4943]
YNL085W MKT1 Protein that forms a complex with Pbp1p that may mediate posttranscriptional regulation of HO endonuclease; involved in propagation of M2 dsRNA satellite of L-A virus; contains a DTG signature typical of retroviral proteases Verified chr14:467133-469625 467133-469625 99.1% 496.46 417.90 454.34 433.69 257.14 242.15 457.18 444.02 249.65 1.69 1.80 1.03 -0.83 -0.32 Covered/w/another[4943]
YNL084C END3 "EH domain-containing protein involved in endocytosis, actin cytoskeletal organization and cell wall morphogenesis; forms a complex with Sla1p and Pan1p" Verified chr14:470055-471104 470055-471104 99.4% 541.32 557.60 512.57 539.40 806.71 491.50 549.46 525.99 649.10 2.03 2.14 2.69 0.30 0.20 Covered/w/another[4943]
YNL083W SAL1 "Probable transporter, member of the Ca2+-binding subfamily of the mitochondrial carrier family, with two EF-hand motifs; Pet9p and Sal1p have an overlapping function critical for viability; polymorphic in different S. cerevisiae strains" Verified chr14:471379-473016 471379-473016 98.8% 90.85 93.32 88.38 82.82 103.83 80.96 92.09 85.60 92.40 0.34 0.35 0.38 0.11 0.68 Matched[4944]
YNL082W PMS1 "ATP-binding protein required for mismatch repair in mitosis and meiosis; functions as a heterodimer with Mlh1p, binds double- and single-stranded DNA via its N-terminal domain, similar to E. coli MutL" Verified chr14:473392-476013 473392-476013 98.8% 83.38 88.01 66.40 53.27 41.30 21.62 85.70 59.83 31.46 0.32 0.24 0.13 -0.93 -0.84 Frag>80[4945,4946,4947]
YNL081C SWS2 "Putative mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S13 ribosomal protein; participates in controlling sporulation efficiency" Verified chr14:476189-476620 476189-476620 99.2% 410.85 443.54 499.56 415.52 672.31 350.16 427.20 457.54 511.23 1.58 1.86 2.12 0.16 0.04 Frag>80[4947,4948]
YNL080C EOS1 Protein involved in N-glycosylation; deletion mutation confers sensitivity to exidative stress and shows synthetic lethality with mutations in the spindle checkpoint genes BUB3 and MAD1; YNL080C is not an essential gene Verified chr14:476933-478033 476933-478033 98.7% 230.97 237.41 249.38 180.36 253.98 184.96 234.19 214.87 219.47 0.86 0.87 0.91 0.03 0.41 Matched[4949]
YNL079C TPM1 "Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; acetylated by the NatB complex and acetylated form binds actin most efficiently" Verified chr14:478567-479166 478567-479166 99.4% 2538.85 2496.93 2208.50 2288.99 3613.75 2426.50 2517.89 2248.74 3020.12 9.29 9.13 12.51 0.43 -0.67 Frag>80[4950,4951]
YNL078W NIS1 Protein localized in the bud neck at G2/M phase; physically interacts with septins; possibly involved in a mitotic signaling network Verified chr14:479769-480992 479769-480992 98.6% 212.85 266.69 249.29 222.79 228.59 120.09 239.77 236.04 174.34 0.89 0.96 0.72 -0.44 -0.40 Matched[4952]
YNL077W APJ1 "Putative chaperone of the HSP40 (DNAJ) family; overexpression interferes with propagation of the [Psi+] prion; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr14:481392-482978 481392-482978 98.6% 31.31 44.09 38.34 46.00 600.59 657.46 37.70 42.17 629.02 0.14 0.17 2.61 3.90 3.44 Matched[4953]
YNL076W MKS1 Pleiotropic negative transcriptional regulator involved in Ras-CAMP and lysine biosynthetic pathways and nitrogen regulation; involved in retrograde (RTG) mitochondria-to-nucleus signaling Verified chr14:483557-485311 483557-485311 98.8% 117.68 128.64 129.79 117.10 162.67 158.63 123.16 123.45 160.65 0.45 0.50 0.67 0.38 0.72 Matched[4954]
YNL075W IMP4 "Component of the SSU processome, which is required for pre-18S rRNA processing; interacts with Mpp10p; member of a superfamily of proteins that contain a sigma(70)-like motif and associate with RNAs" Verified chr14:485608-486480 485608-486480 98.6% 243.88 142.84 180.01 121.94 19.74 8.13 193.36 150.97 13.94 0.71 0.61 0.06 -3.44 -2.97 Matched[4955]
YNL074C MLF3 Serine-rich protein of unknown function; overproduction suppresses the growth inhibition caused by exposure to the immunosuppressant leflunomide Verified chr14:486767-488125 486767-488125 98.5% 277.21 298.88 277.21 286.18 741.97 721.05 288.04 281.69 731.51 1.06 1.14 3.03 1.38 1.58 Matched[4956]
YNL073W MSK1 "Mitochondrial lysine-tRNA synthetase, required for import of both aminoacylated and deacylated forms of tRNA(Lys) into mitochondria" Verified chr14:488387-490117 488387-490117 98.6% 168.69 172.79 185.09 152.29 241.32 199.74 170.74 168.69 220.53 0.63 0.68 0.91 0.39 0.58 Matched[4957]
YNL072W RNH201 "Ribonuclease H2 catalytic subunit, removes RNA primers during Okazaki fragment synthesis; cooperates with Rad27p nuclease" Verified chr14:490318-491241 490318-491241 98.3% 89.19 84.79 94.70 81.48 88.09 40.74 86.99 88.09 64.42 0.32 0.36 0.27 -0.45 -0.99 Matched[4958]
YNL071W LAT1 "Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex, which catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA" Verified chr14:491524-492972 491524-492972 98.6% 1709.24 2469.06 1813.49 1878.55 2095.44 2408.89 2089.15 1846.02 2252.16 7.71 7.49 9.33 0.29 0.71 Matched[4959]
YNL070W TOM7 Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; promotes assembly and stability of the TOM complex Verified chr14:493367-493549 493367-493549 99.1% 1196.14 1008.73 1080.39 942.58 1570.97 953.61 1102.43 1011.48 1262.29 4.07 4.11 5.23 0.32 -0.22 Matched[4960]
YNL069C RPL16B "N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5.8 S rRNA; has similarity to Rpl16Ap, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p" Verified chr14:493957-495002 493957-494525,494975-495002 90.5% 8197.47 7251.47 7194.08 6277.69 1843.88 1364.39 7724.47 6735.88 1604.13 28.51 27.34 6.65 -2.07 -2.44 Frag>80[4961,4962]
YNL068C FKH2 Forkhead family transcription factor with a major role in the expression of G2/M phase genes; positively regulates transcriptional elongation; negative role in chromatin silencing at HML and HMR; substrate of the Cdc28p/Clb5p kinase Verified chr14:495702-498290 495702-498290 99.0% 106.15 108.88 96.78 75.32 65.95 85.47 107.52 86.05 75.71 0.40 0.35 0.31 -0.18 0.65 Matched[4963]
YNL067W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr14:498539-498685 498539-498685 98.2% 6.92 13.85 0.00 0.00 6.92 48.47 10.39 0.00 27.70 0.04 0.00 0.11 Inf 0.49 Covered/w/another[4963]
YNL067W-B Putative protein of unknown function Uncharacterized chr14:499418-499558 499418-499558 98.7% 0.00 7.18 0.00 0.00 7.18 14.37 3.59 0.00 10.78 0.01 0.00 0.04 Inf NaN
YNL067W RPL9B "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Ap and has similarity to E. coli L6 and rat L9 ribosomal proteins" Verified chr14:499682-500257 499682-500257 51.6% 3226.24 2987.38 2593.78 1894.03 1160.64 534.90 3106.81 2243.90 847.77 11.47 9.11 3.51 -1.40 -2.08 Frag>80[4964,4965]
YNL066W SUN4 "Cell wall protein related to glucanases, possibly involved in cell wall septation; member of the SUN family" Verified chr14:501157-502778 501157-501158,501504-502778 98.6% 866.95 793.91 714.52 577.97 278.66 193.71 830.43 646.25 236.19 3.07 2.62 0.98 -1.45 -1.05 Matched[4966]
YNL065W AQR1 "Plasma membrane multidrug transporter of the major facilitator superfamily, confers resistance to short-chain monocarboxylic acids and quinidine" Verified chr14:503725-505485 503725-505485 98.8% 206.33 202.30 102.30 81.04 14.37 6.90 204.32 91.67 10.63 0.75 0.37 0.04 -3.11 -3.27 Matched[4967]
YNL064C YDJ1 Protein chaperone involved in regulation of the HSP90 and HSP70 functions; involved in protein translocation across membranes; member of the DnaJ family Verified chr14:505869-507098 505869-507098 99.2% 1133.49 642.56 876.14 850.73 4596.25 4104.50 888.02 863.44 4350.37 3.28 3.50 18.03 2.33 1.64 Frag>80[4968,4969]
YNL063W MTQ1 S-adenosylmethionine-dependent Methyltransferase; methylates translational release factor Mrf1p; similar to E.coli PrmC; is not an essential gene Verified chr14:507759-508703 507759-508703 98.7% 99.72 72.91 97.57 76.13 258.41 167.27 86.32 86.85 212.84 0.32 0.35 0.88 1.29 1.69 Matched[4970]
YNL062C GCD10 "Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p, required for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression" Verified chr14:508777-510213 508777-510213 99.2% 159.23 89.09 111.53 99.61 11.22 5.61 124.16 105.57 8.42 0.46 0.43 0.03 -3.65 -2.90 Matched[4971]
YNL061W NOP2 "Probable RNA m(5)C methyltransferase, essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis; localized to the nucleolus; constituent of 66S pre-ribosomal particles" Verified chr14:510541-512397 510541-512397 98.5% 404.09 243.33 279.97 244.42 27.34 10.94 323.71 262.20 19.14 1.19 1.06 0.08 -3.78 -3.28 Frag>80[4972,4973]
YNL059C ARP5 "Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes" Verified chr14:512669-514936 512669-514936 99.3% 285.46 251.28 244.62 242.84 201.55 160.27 268.37 243.73 180.91 0.99 0.99 0.75 -0.43 0.01 Matched[4974]
YNL057W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr14:516404-516736 516404-516736 98.5% 234.76 265.24 207.32 259.15 454.27 384.15 250.00 233.23 419.21 0.92 0.95 1.74 0.85 -0.04 Matched[4976]
YNL058C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YNL058C is not an essential gene Uncharacterized chr14:515764-516714 515764-516714 98.6% 310.33 365.79 261.28 289.00 547.08 452.17 338.06 275.14 499.62 1.25 1.12 2.07 0.86 1.08 Matched[4976]
YNL056W OCA2 Putative protein with similarity to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene Verified chr14:517250-517843 517250-517843 98.4% 430.92 335.16 314.64 324.90 347.13 160.74 383.04 319.77 253.94 1.41 1.30 1.05 -0.33 -0.18 Matched[4977]
YNL055C POR1 "Mitochondrial porin (voltage-dependent anion channel), outer membrane protein required for the maintenance of mitochondrial osmotic stability and mitochondrial membrane permeability; phosphorylated" Verified chr14:517995-518846 517995-518846 98.5% 1956.09 3441.34 2384.03 2895.40 5551.21 5256.78 2698.72 2639.71 5403.99 9.96 10.72 22.39 1.03 0.71 Frag>80[4978,4979,4980]
YNL054W VAC7 Integral vacuolar membrane protein involved in vacuole inheritance and morphology; activates Fab1p kinase activity under basal conditions and also after hyperosmotic shock Verified chr14:526087-529584 526087-529584 98.8% 76.36 69.13 70.00 67.11 66.82 84.17 72.75 68.55 75.49 0.27 0.28 0.31 0.14 0.61 Covered/w/another[4984]
YNL053W MSG5 Dual-specificity protein phosphatase required for maintenance of a low level of signaling through the cell integrity pathway; regulates and is regulated by Slt2p; also required for adaptive response to pheromone Verified chr14:529943-531412 529943-531412 98.8% 88.13 97.77 89.51 84.69 36.49 18.59 92.95 87.10 27.54 0.34 0.35 0.11 -1.66 -0.60 Covered/w/another[4984]
YNL052W COX5A "Subunit Va of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; predominantly expressed during aerobic growth while its isoform Vb (Cox5Bp) is expressed during anaerobic growth" Verified chr14:531726-532187 531726-532187 98.4% 420.24 470.85 583.06 666.67 695.27 523.65 445.54 624.86 609.46 1.64 2.54 2.53 -0.04 -0.25 Matched[4985]
YNL051W COG5 "Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" Verified chr14:532660-533871 532660-533871 99.1% 120.67 142.31 118.18 122.34 190.58 134.82 131.49 120.26 162.70 0.49 0.49 0.67 0.44 0.61 Covered/w/another[4986]
YNL050C Putative protein of unknown function; YNL050c is not an essential gene Uncharacterized chr14:534080-534983 534080-534875,534967-534983 99.4% 169.50 132.38 134.86 121.25 120.01 55.68 150.94 128.05 87.84 0.56 0.52 0.36 -0.54 -0.50 Covered/w/another[4986]
YNL049C SFB2 "Probable component of COPII coated vesicles that binds to Sec23p; similar to and functionally redundant with Sec24p, but expressed at low levels; involved in ER to Golgi transport and in autophagy" Verified chr14:535282-537912 535282-537912 99.0% 177.45 146.34 120.99 124.45 89.88 99.48 161.89 122.72 94.68 0.60 0.50 0.39 -0.37 0.10 Covered/w/another[4986]
YNL048W ALG11 "Alpha-1,2-mannosyltransferase, catalyzes sequential addition of the two terminal alpha 1,2-mannose residues to the Man5GlcNAc2-PP-dolichol intermediate during asparagine-linked glycosylation in the ER" Verified chr14:538174-539820 538174-539820 98.9% 184.17 168.21 175.58 170.05 112.34 84.72 176.19 172.81 98.53 0.65 0.70 0.41 -0.81 -0.56 Matched[4987]
YNL047C SLM2 "Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; subunit of and phosphorylated by the TORC2 complex" Verified chr14:539912-541882 539912-541882 98.9% 69.79 75.94 70.81 52.85 65.17 32.84 72.87 61.83 49.00 0.27 0.25 0.20 -0.34 -0.04 Matched[4988]
YNL046W Putative protein of unknown function; expression depends on Swi5p; GFP-fusion protein localizes to the endoplasmic reticulum; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) Uncharacterized chr14:542305-542823 542305-542823 98.7% 212.80 273.33 208.90 160.09 339.71 148.38 243.07 184.50 244.04 0.90 0.75 1.01 0.40 0.04 Covered/w/another[4989]
YNL045W "Leucyl aminopeptidase (leukotriene A4 hydrolase) with epoxide hydrolase activity, metalloenzyme containing one zinc atom; role in vivo is not defined; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus" Verified chr14:542964-544979 542964-544979 99.0% 226.38 327.05 273.96 267.45 463.27 436.73 276.71 270.70 450.00 1.02 1.10 1.86 0.73 1.05 Covered/w/another[4989]
YNL044W YIP3 "Protein localized to COPII vesicles, proposed to be involved in ER to Golgi transport; interacts with members of the Rab GTPase family and Yip1p; also interacts with Rtn1p" Verified chr14:545269-545878 545269-545292,545372-545878 99.2% 609.59 522.23 560.22 537.43 634.28 332.33 565.91 548.82 483.30 2.09 2.23 2.00 -0.18 -0.17 Matched[4990]
YNL043C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YIP3/YNL044W" Dubious chr14:545590-545910 545590-545910 99.1% 704.31 572.25 666.58 628.85 720.03 327.00 638.28 647.71 523.52 2.36 2.63 2.17 -0.31 -0.80 Matched[4990]
YNL042W-B Putative protein of unknown function Uncharacterized chr14:547114-547371 547114-547371 72.0% 5.38 10.77 5.38 0.00 5.38 10.77 8.08 2.69 8.08 0.03 0.01 0.03 1.58 NaN
YNL042W BOP3 "Protein of unknown function, potential Cdc28p substrate; overproduction suppresses a pam1 slv3 double null mutation and confers resistance to methylmercury" Verified chr14:548101-549291 548101-549291 98.8% 67.97 77.32 67.97 45.88 124.90 77.32 72.64 56.93 101.11 0.27 0.23 0.42 0.83 0.99 Matched[4992]
YNL041C COG6 "Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" Verified chr14:549469-551988 549469-551988 99.3% 178.23 172.64 150.26 145.86 119.89 90.31 175.43 148.06 105.10 0.65 0.60 0.44 -0.49 -0.20 Matched[4993]
YNL040W Putative protein of unknown function with strong similarity to alanyl-tRNA synthases from Eubacteria; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL040W is not an essential gene Uncharacterized chr14:553381-554751 553381-554751 98.7% 108.68 104.98 104.98 105.72 136.04 116.07 106.83 105.35 126.06 0.39 0.43 0.52 0.26 0.22 Covered/w/another[4995]
YNL039W BDP1 "Essential subunit of RNA polymerase III transcription factor (TFIIIB), which is involved in transcription of genes encoding tRNAs, 5S rRNA, U6 snRNA, and other small RNAs" Verified chr14:555049-556833 555049-556833 98.4% 177.70 193.08 158.90 150.36 203.33 163.46 185.39 154.63 183.39 0.68 0.63 0.76 0.25 0.51 Covered/w/another[4995]
YNL038W GPI15 "Protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-H protein" Verified chr14:557021-557784 557021-557611,557686-557784 99.0% 273.66 241.46 213.66 204.88 182.93 42.44 257.56 209.27 112.68 0.95 0.85 0.47 -0.89 -0.73 Covered/w/another[4995]
YNL037C IDH1 "Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle" Verified chr14:557921-559003 557921-559003 98.9% 631.33 1087.09 543.54 630.40 1276.68 940.46 859.21 586.97 1108.57 3.17 2.38 4.59 0.92 0.86 Matched[4996]
YNL036W NCE103 Carbonic anhydrase; poorly transcribed under aerobic conditions and at an undetectable level under anaerobic conditions; involved in non-classical protein export pathway Verified chr14:559815-560480 559815-560480 99.1% 124.21 143.90 180.26 124.21 493.81 177.23 134.06 152.23 335.52 0.49 0.62 1.39 1.14 0.57 Frag>80[4997,4998]
YNL035C Putative protein of unknown function with similarity to proteins containing WD-40 domains; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YNL035C is not an essential gene Uncharacterized chr14:568523-569692 568523-569692 99.1% 145.71 100.88 112.95 96.57 97.43 96.57 123.29 104.76 97.00 0.46 0.43 0.40 -0.11 0.19 Matched[5000]
YNL034W Putative protein of unknown function; YNL034W is not an essential gene Uncharacterized chr14:570478-572316 570478-572316 19.3% 8.47 2.82 5.64 0.00 14.11 11.29 5.64 2.82 12.70 0.02 0.01 0.05 2.17 0.54
YNL033W Putative protein of unknown function Uncharacterized chr14:573000-573854 573000-573854 0.5% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 1.13
YNL032W SIW14 Tyrosine phosphatase that plays a role in actin filament organization and endocytosis; localized to the cytoplasm Verified chr14:574507-575352 574507-575352 98.5% 178.74 142.75 164.34 128.36 170.34 76.77 160.74 146.35 123.56 0.59 0.59 0.51 -0.24 -0.61 Matched[5001]
YNL031C HHT2 "One of two identical histone H3 proteins (see also HHT1); core histone required for chromatin assembly, involved in heterochromatin-mediated telomeric and HM silencing; regulated by acetylation, methylation, and mitotic phosphorylation" Verified chr14:575641-576051 575641-576051 62.7% 6678.73 5875.89 6477.05 5449.26 9928.89 6380.09 6277.31 5963.15 8154.49 23.17 24.21 33.79 0.45 -0.77 Matched[5002]
YNL030W HHF2 One of two identical histone H4 proteins (see also HHF1); core histone required for chromatin assembly and chromosome function; contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity Verified chr14:576728-577039 576728-577039 31.7% 6581.30 5034.54 6156.70 4599.83 6803.71 3598.99 5807.92 5378.26 5201.35 21.44 21.83 21.55 -0.05 -0.69 Matched[5004]
YNL028W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr14:578680-578997 578680-578997 99.3% 12.67 9.50 25.35 15.84 19.01 9.50 11.09 20.59 14.26 0.04 0.08 0.06 -0.53 0.05 Overlap[5005]
YNL029C KTR5 Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family Verified chr14:577206-578774 577206-578774 99.2% 85.49 74.56 75.85 57.21 77.78 58.49 80.03 66.53 68.14 0.30 0.27 0.28 0.03 0.22 Matched[5005]
YNL027W CRZ1 Transcription factor that activates transcription of genes involved in stress response; nuclear localization is positively regulated by calcineurin-mediated dephosphorylation Verified chr14:579581-581617 579581-581617 98.2% 100.50 96.50 90.50 98.00 99.00 95.50 98.50 94.25 97.25 0.36 0.38 0.40 0.05 0.42 Covered/w/another[5006]
YNL026W SAM50 "Essential component of the Sorting and Assembly Machinery (SAM or Tob complex) of the mitochondrial outer membrane, which binds precursors of beta-barrel proteins and facilitates their outer membrane insertion; homologous to bacterial Omp85" Verified chr14:581921-583375 581921-583375 98.9% 155.74 155.74 152.26 146.70 254.47 207.19 155.74 149.48 230.83 0.57 0.61 0.96 0.63 0.91 Covered/w/another[5006]
YNL025C SSN8 "Cyclin-like component of the RNA polymerase II holoenzyme, involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression and telomere maintenance" Verified chr14:584321-585292 584321-585292 99.1% 73.74 98.67 98.67 82.05 187.99 111.14 86.21 90.36 149.57 0.32 0.37 0.62 0.73 1.08 Covered/w/another[5006]
YNL024C-A Putative protein of unknown function; YNL024C-A is an essential gene Uncharacterized chr14:586603-586821 586603-586821 98.8% 517.42 526.66 563.62 531.28 549.76 448.12 522.04 547.45 498.94 1.93 2.22 2.07 -0.13 NaN Matched[5008]
YNL024C Putative protein of unknown function with seven beta-strand methyltransferase motif; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL024C is not an essential gene Uncharacterized chr14:587108-587848 587108-587848 99.3% 93.74 124.99 52.99 38.04 20.38 8.15 109.37 45.51 14.27 0.40 0.18 0.06 -1.67 -2.15 Matched[5009]
YNL023C FAP1 "Protein that binds to Fpr1p (FKBP12), conferring rapamycin resistance by competing with rapamycin for Fpr1p binding; has similarity to putative transcription factors, including D. melanogaster shuttle craft and human NFX1" Verified chr14:588264-591161 588264-591161 99.0% 92.69 60.63 49.83 38.33 13.94 6.97 76.66 44.08 10.45 0.28 0.18 0.04 -2.08 -1.43 Frag>80[5010,5011,5012]
YNL022C Putative protein of unknown function with seven beta-strand methyltransferase motif similar to NOP2/YNL061W; green fluorescent protein (GFP)-fusion protein localizes to a single spot in the nucleus; YNL022C is not an essential gene Uncharacterized chr14:591428-592900 591428-592900 99.1% 137.68 96.58 93.84 82.19 33.56 18.49 117.13 88.02 26.03 0.43 0.36 0.11 -1.76 -1.22 Matched[5013]
YNL021W HDA1 "Putative catalytic subunit of a class II histone deacetylase complex that also contains Hda2p and Hda3p; Hda1p interacts with the Hda2p-Hda3p subcomplex to form an active tetramer; deletion increases histone H2B, H3 and H4 acetylation" Verified chr14:593228-595348 593228-595348 98.6% 94.65 93.22 92.26 72.66 80.79 98.00 93.93 82.46 89.39 0.35 0.33 0.37 0.12 0.12 Covered[5014]
YNL020C ARK1 Serine/threonine protein kinase involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis Verified chr14:595624-597540 595624-597540 99.0% 135.94 147.00 132.77 89.57 108.54 75.87 141.47 111.17 92.20 0.52 0.45 0.38 -0.27 0.36 Frag<80[5015,5016]
YNL019C Putative protein of unknown function Uncharacterized chr14:598377-599231 598377-599231 1.3% 0.00 0.00 89.55 0.00 89.55 0.00 0.00 44.78 44.78 0.00 0.18 0.19 0.00 1.20
YNL018C Putative protein of unknown function Uncharacterized chr14:599937-601775 599937-601775 18.1% 12.01 9.00 18.01 9.00 6.00 6.00 10.51 13.51 6.00 0.04 0.05 0.02 -1.17 0.17
YNL017C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the tRNA ORF tI(AAU)N2" Dubious chr14:602139-602477 602139-602477 58.2% 40.57 5.07 5.07 0.00 0.00 40.57 22.82 2.54 20.29 0.08 0.01 0.08 3.00 0.15 Matched[5018]
YNL016W PUB1 "Poly(A)+ RNA-binding protein, abundant mRNP-component protein that binds mRNA and is required for stability of a number of mRNAs; not reported to associate with polyribosomes" Verified chr14:602908-604269 602908-604269 98.1% 1283.60 1142.89 1146.64 1173.58 622.72 657.89 1213.25 1160.11 640.30 4.48 4.71 2.65 -0.86 -0.52 Matched[5019]
YNL015W PBI2 "Cytosolic inhibitor of vacuolar proteinase B, required for efficient vacuole inheritance; with thioredoxin forms protein complex LMA1, which assists in priming SNARE molecules and promotes vacuole fusion" Verified chr14:605385-605612 605385-605612 98.5% 739.01 1166.39 801.34 885.92 7283.25 4126.88 952.70 843.63 5705.06 3.52 3.42 23.64 2.76 2.03 Matched[5021]
YNL014W HEF3 Translational elongation factor EF-3; paralog of YEF3 and member of the ABC superfamily; stimulates EF-1 alpha-dependent binding of aminoacyl-tRNA by the ribosome; normally expressed in zinc deficient cells Verified chr14:606320-609454 606320-609454 97.2% 18.06 32.17 16.09 12.15 46.95 33.82 25.12 14.12 40.38 0.09 0.06 0.17 1.52 1.38 Covered/w/another[5022]
YNL013C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF HEF3/YNL014W" Dubious chr14:609134-609511 609134-609511 98.3% 59.23 64.62 51.16 24.23 107.70 40.39 61.93 37.69 74.04 0.23 0.15 0.31 0.97 0.14 Covered/w/another[5022]
YNL012W SPO1 "Meiosis-specific protein with similarity to phospholipase B, required for meiotic spindle pole body duplication and separation; required for spore formation" Verified chr14:609687-611666 609687-609791,609876-611666 98.9% 27.73 37.33 33.06 27.19 74.12 57.59 32.53 30.13 65.85 0.12 0.12 0.27 1.13 1.08 Covered/w/another[5022]
YNL011C Putative protein of unknown function; YNL011C is not an essential gene Uncharacterized chr14:611837-613171 611837-613171 99.1% 107.28 148.83 111.06 87.64 285.58 118.61 128.06 99.35 202.10 0.47 0.40 0.84 1.02 -0.22 Frag>80[5023,5024]
YNL010W Putative protein of unknown function with similarity to phosphoserine phosphatases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; homozygous diploid mutant shows an increase in glycogen accumulation Uncharacterized chr14:613636-614361 613636-614361 98.7% 1758.96 1839.93 1805.03 1705.91 992.55 893.44 1799.44 1755.47 943.00 6.64 7.13 3.91 -0.90 -0.91 Matched[5025]
YNL009W IDP3 "Peroxisomal NADP-dependent isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate with the formation of NADP(H+), required for growth on unsaturated fatty acids" Verified chr14:614822-616084 614822-616084 98.7% 29.67 32.88 34.49 36.89 69.77 66.56 31.28 35.69 68.17 0.12 0.14 0.28 0.93 1.09 Matched[5026]
YNL008C ASI3 Putative integral membrane E3 ubiquitin ligase; acts with Asi1p and Asi2p to ensure the fidelity of SPS-sensor signalling by maintaining the dormant repressed state of gene expression in the absence of inducing signals Verified chr14:616212-618221 616212-618221 99.2% 115.91 145.01 111.39 93.83 130.96 89.82 130.46 102.61 110.39 0.48 0.42 0.46 0.11 0.23 Matched[5027]
YNL007C SIS1 Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p; not functionally redundant with Ydj1p due to due to substrate specificity; shares similarity with bacterial DnaJ proteins Verified chr14:618509-619567 618509-619567 99.0% 1069.44 1150.53 1141.95 1376.63 13234.01 11524.43 1109.99 1259.29 12379.22 4.10 5.11 51.29 3.30 2.23 Frag>80[5028,5029,5030]
YNL006W LST8 Protein required for the transport of amino acid permease Gap1p from the Golgi to the cell surface; component of the TOR signaling pathway; associates with both Tor1p and Tor2p; contains a WD-repeat Verified chr14:620069-620980 620069-620980 98.7% 184.32 200.98 169.89 172.11 3259.00 1708.89 192.65 171.00 2483.95 0.71 0.69 10.29 3.86 2.57 Frag>80[5030,5031,5032,5033]
YNL005C MRP7 Mitochondrial ribosomal protein of the large subunit Verified chr14:621315-622430 621315-622430 99.3% 338.41 338.41 340.21 311.34 397.97 259.90 338.41 325.78 328.93 1.25 1.32 1.36 0.01 0.06 Matched[5034]
YNL004W HRB1 "Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Gbp2p and Npl3p" Verified chr14:622917-624623 622917-622946,623289-624623 98.3% 305.62 309.35 267.60 240.77 165.48 121.50 307.48 254.19 143.49 1.14 1.03 0.59 -0.82 -0.52 Covered/w/another[5035]
YNL003C PET8 "S-adenosylmethionine transporter of the mitochondrial inner membrane, member of the mitochondrial carrier family; required for biotin biosynthesis and respiratory growth" Verified chr14:624977-625831 624977-625831 98.8% 161.00 217.83 200.07 174.02 280.57 189.41 189.41 187.05 234.99 0.70 0.76 0.97 0.33 -0.27 Covered/w/another[5035]
YNL002C RLP7 Nucleolar protein with similarity to large ribosomal subunit L7 proteins; constituent of 66S pre-ribosomal particles; plays an essential role in processing of precursors to the large ribosomal subunit RNAs Verified chr14:626176-627144 626176-627144 99.3% 580.88 301.35 365.78 313.82 45.72 10.39 441.12 339.80 28.06 1.63 1.38 0.12 -3.60 -3.94 Frag>80[5036,5037]
YNL001W DOM34 "Endoribonuclease; functions in no-go mRNA decay, protein translation to promote G1 progression and differentiation, required for meiotic cell division; similar to the eukaryotic Pelota" Verified chr14:627458-628618 627458-628618 98.8% 238.90 172.64 204.90 166.53 81.96 61.03 205.77 185.72 71.50 0.76 0.75 0.30 -1.38 -1.27 Matched[5038]
YNR001C CIT1 "Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate; the rate-limiting enzyme of the TCA cycle; nuclear encoded mitochondrial protein" Verified chr14:629624-631063 629624-631063 99.0% 567.39 855.64 990.30 1192.99 2738.75 2626.53 711.51 1091.64 2682.64 2.63 4.43 11.12 1.30 1.68 Frag>80[5039,5040,5041]
YNR001W-A Dubious open reading frame unlikely to encode a functional protein; identified by homology Dubious chr14:631265-631483 631265-631483 98.3% 0.00 4.64 0.00 0.00 4.64 18.58 2.32 0.00 11.61 0.01 0.00 0.05 Inf 0.81 Frag<80[5041]
YNR002C ATO2 "Putative transmembrane protein involved in export of ammonia, a starvation signal that promotes cell death in aging colonies; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family; homolog of Ady2p and Y. lipolytica Gpr1p" Verified chr14:633010-633858 633010-633858 98.4% 41.91 69.45 43.11 68.25 238.29 142.49 55.68 55.68 190.39 0.21 0.23 0.79 1.77 1.63 Frag>80[5042,5043]
YNR003W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene RPC34/YNR003C" Dubious chr14:634422-634520 634422-634520 99.5% 264.07 203.13 213.29 182.82 50.78 40.63 233.60 198.05 45.70 0.86 0.80 0.19 -2.12 NaN Covered/w/another[5044]
YNR003C RPC34 RNA polymerase III subunit C34; interacts with TFIIIB70 and is a key determinant in pol III recruitment by the preinitiation complex Verified chr14:634346-635299 634346-635299 99.3% 219.49 155.12 135.07 110.80 47.49 30.60 187.30 122.93 39.04 0.69 0.50 0.16 -1.65 -1.44 Matched[5044]
YNR004W Putative protein of unknown function; haploid disruptant exhibits slow growth rate on glucose-minimal medium at 15 C Uncharacterized chr14:635945-636385 635945-636385 98.7% 105.65 87.27 75.79 59.71 101.05 82.68 96.46 67.75 91.87 0.36 0.28 0.38 0.44 0.56 Matched[5046]
YNR006W VPS27 "Endosomal protein that forms a complex with Hse1p; required for recycling Golgi proteins, forming lumenal membranes and sorting ubiquitinated proteins destined for degradation; has Ubiquitin Interaction Motifs which bind ubiquitin (Ubi4p)" Verified chr14:636988-638856 636988-638856 98.7% 125.72 123.01 167.45 124.64 167.99 139.81 124.36 146.04 153.90 0.46 0.59 0.64 0.08 0.86 Matched[5047]
YNR005C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr14:636933-637337 636933-637337 98.7% 62.53 62.53 77.54 77.54 57.53 77.54 62.53 77.54 67.54 0.23 0.31 0.28 -0.20 0.15 Covered/w/another[5047]
YNR007C ATG3 "Protein involved in autophagy; E2-like enzyme that plays a role in formation of Atg8p-phosphatidylethanolamine conjugates, which are involved in membrane dynamics during autophagy" Verified chr14:639184-640116 639184-640116 99.4% 69.02 92.75 93.83 105.69 143.43 130.49 80.88 99.76 136.96 0.30 0.40 0.57 0.46 0.87 Matched[5048]
YNR008W LRO1 Acyltransferase that catalyzes diacylglycerol esterification; one of several acyltransferases that contribute to triglyceride synthesis; putative homolog of human lecithin cholesterol acyltransferase Verified chr14:640398-642383 640398-642383 98.5% 161.09 213.26 167.74 149.84 145.75 144.22 187.18 158.79 144.98 0.69 0.64 0.60 -0.13 0.29 Covered/w/another[5049]
YNR009W NRM1 Transcriptional co-repressor of MBF (MCB binding factor)-regulated gene expression; Nrm1p associates stably with promoters via MBF to repress transcription upon exit from G1 phase Verified chr14:642692-643441 642692-643441 98.9% 225.21 215.77 176.66 165.87 111.93 98.44 220.49 171.26 105.19 0.81 0.70 0.44 -0.70 -0.34 Covered/w/another[5049]
YNR010W CSE2 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; component of the Med9/10 module; required for regulation of RNA polymerase II activity Verified chr14:643746-644195 643746-644195 99.0% 74.09 69.60 76.33 76.33 181.85 112.25 71.84 76.33 147.05 0.27 0.31 0.61 0.95 1.06 Covered/w/another[5049]
YNR011C PRP2 "RNA-dependent ATPase in the DEAH-box family, required for activation of the spliceosome before the first transesterification step in RNA splicing" Verified chr14:644322-646952 644322-646952 99.3% 70.05 70.81 55.12 49.38 51.29 56.27 70.43 52.25 53.78 0.26 0.21 0.22 0.04 0.47 Covered/w/another[5049]
YNR012W URK1 "Uridine/cytidine kinase, component of the pyrimidine ribonucleotide salvage pathway that converts uridine into UMP and cytidine into CMP; involved in the pyrimidine deoxyribonucleotide salvage pathway, converting deoxycytidine into dCMP" Verified chr14:647434-648939 647434-648939 98.9% 110.10 84.59 61.09 49.68 6.71 6.04 97.34 55.38 6.38 0.36 0.22 0.03 -3.12 -1.10 Matched[5050]
YNR013C PHO91 "Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth" Verified chr14:649030-651714 649030-651714 98.6% 258.06 284.13 263.73 262.97 131.49 181.74 271.10 263.35 156.61 1.00 1.07 0.65 -0.75 0.20 Matched[5051]
YNR014W "Putative protein of unknown function; expression is cell-cycle regulated, Azf1p-dependent, and heat-inducible" Uncharacterized chr14:652467-653105 652467-653105 98.8% 34.86 66.56 142.62 120.44 610.10 540.38 50.71 131.53 575.24 0.19 0.53 2.38 2.13 2.28 Frag>80[5052,5053]
YNR015W SMM1 "Dihydrouridine synthase, member of a family of dihydrouridine synthases including Dus1p, Smm1p, Dus3p, and Dus4p; modifies uridine residues at position 20 of cytoplasmic tRNAs" Verified chr14:653389-654543 653389-654543 98.5% 134.50 83.51 125.71 70.33 39.56 25.49 109.01 98.02 32.53 0.40 0.40 0.13 -1.59 -1.23 Frag>80[5053,5054,5055,5056]
YNR016C ACC1 "Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA; required for de novo biosynthesis of long-chain fatty acids" Verified chr14:654675-661376 654675-661376 98.9% 596.86 806.33 519.59 481.11 189.24 216.86 701.59 500.35 203.05 2.59 2.03 0.84 -1.30 -0.67 Frag<80[5055,5056,5057,5058]
YNR017W TIM23 "Essential protein of the mitochondrial inner membrane, component of the mitochondrial import system" Verified chr14:662915-663583 662915-663583 98.4% 1063.09 1137.51 1037.27 946.15 583.18 441.94 1100.30 991.71 512.56 4.06 4.03 2.12 -0.95 -0.76 Covered/w/another[5060]
YNR018W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr14:664272-664946 664272-664946 98.3% 559.16 765.64 494.35 470.23 426.53 348.15 662.40 482.29 387.34 2.45 1.96 1.60 -0.32 -0.28 Covered/w/another[5060]
YNR019W ARE2 "Acyl-CoA:sterol acyltransferase, isozyme of Are1p; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the presence of oxygen" Verified chr14:665341-667269 665341-667269 98.8% 96.06 146.45 99.21 109.18 184.24 297.10 121.25 104.19 240.67 0.45 0.42 1.00 1.21 1.92 Covered/w/another[5061]
YNR020C ATP23 "Putative metalloprotease of the mitochondrial inner membrane, required for processing of Atp6p; has an additional role in assembly of the F0 sector of the F1F0 ATP synthase complex" Verified chr14:667412-668224 667412-668224 99.3% 158.58 121.41 147.43 131.32 121.41 91.68 140.00 139.38 106.55 0.52 0.57 0.44 -0.39 -0.60 Covered/w/another[5061]
YNR021W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YNR021W is not an essential gene Uncharacterized chr14:668379-669593 668379-669593 99.0% 1087.88 1107.01 1058.77 1086.22 630.44 437.48 1097.45 1072.50 533.96 4.05 4.35 2.21 -1.01 -0.89 Matched[5062]
YNR022C MRPL50 "Mitochondrial ribosomal protein of the large subunit, not essential for mitochondrial translation" Verified chr14:669776-670195 669776-670195 99.3% 515.38 534.56 551.34 443.47 699.96 441.07 524.97 497.40 570.52 1.94 2.02 2.36 0.20 -0.53 Matched[5063]
YNR023W SNF12 73 kDa subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; homolog of Rsc6p subunit of the RSC chromatin remodeling complex; deletion mutants are temperature-sensitive Verified chr14:670420-672120 670420-672120 98.8% 77.38 72.02 89.88 71.43 79.16 75.00 74.70 80.65 77.08 0.28 0.33 0.32 -0.07 0.33 Matched[5064]
YNR024W "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the nucleus" Verified chr14:672411-672971 672411-672971 98.1% 208.89 172.56 150.76 90.82 87.19 21.80 190.72 120.79 54.49 0.70 0.49 0.23 -1.15 -1.54 Matched[5065]
YNR025C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; deletion reduces expression of PIS1 gene encoding phosphatidylinositol synthase" Dubious chr14:672704-673063 672704-673063 98.2% 245.99 220.55 147.03 104.62 115.93 48.07 233.27 125.82 82.00 0.86 0.51 0.34 -0.62 -0.36 Matched[5065]
YNR026C SEC12 "Guanine nucleotide exchange factor (GEF); glycosylated integral membrane protein of the endoplasmic reticulum, important for the initiation of transport vesicle budding from the endoplasmic reticulum through activation of the GTPase Sar1p" Verified chr14:673276-674691 673276-674691 99.1% 137.56 145.40 128.30 110.48 108.34 99.79 141.48 119.39 104.06 0.52 0.48 0.43 -0.20 0.18 Matched[5066]
YNR027W BUD17 Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern Verified chr14:674925-675878 674925-675878 98.5% 172.34 201.06 111.70 108.51 93.62 87.23 186.70 110.11 90.43 0.69 0.45 0.37 -0.28 -0.11 Covered/w/another[5067]
YNR028W CPR8 "Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; similarity to Cpr4p suggests a potential role in the secretory pathway" Verified chr14:676179-677105 676179-677105 98.7% 197.84 227.35 259.05 264.52 212.05 178.17 212.60 261.78 195.11 0.78 1.06 0.81 -0.42 0.00 Covered/w/another[5067]
YNR029C "Putative protein of unknown function, deletion confers reduced fitness in saline" Uncharacterized chr14:677201-678490 677201-678490 99.2% 155.47 145.31 151.56 136.72 73.44 57.81 150.39 144.14 65.62 0.56 0.59 0.27 -1.14 -0.70 Covered/w/another[5067]
YNR030W ALG12 "Alpha-1,6-mannosyltransferase localized to the ER; responsible for the addition of the alpha-1,6 mannose to dolichol-linked Man7GlcNAc2, acts in the dolichol pathway for N-glycosylation" Verified chr14:678801-680456 678801-680456 99.1% 277.29 275.46 283.39 301.06 243.77 257.79 276.38 292.22 250.78 1.02 1.19 1.04 -0.22 0.26 Covered/w/another[5067]
YNR031C SSK2 "MAP kinase kinase kinase of the HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress" Verified chr14:680696-685435 680696-685435 99.2% 96.99 94.86 89.33 84.86 65.93 69.34 95.92 87.10 67.64 0.35 0.35 0.28 -0.36 0.15 Frag>80[5068]
YNR032W PPG1 "Putative serine/threonine protein phosphatase, required for glycogen accumulation; interacts with Tap42p, which binds to and regulates other protein phosphatases" Verified chr14:686012-687118 686012-687118 98.6% 149.28 163.93 143.78 130.05 185.91 97.99 156.61 136.92 141.95 0.58 0.56 0.59 0.05 0.08 Matched[5069]
YNR032C-A HUB1 "Ubiquitin-like protein modifier, may function in modification of Sph1p and Hbt1p, functionally complemented by the human or S. pombe ortholog; mechanism of Hub1p adduct formation not yet clear" Verified chr14:687245-687466 687245-687466 99.5% 393.96 276.23 285.28 212.83 624.91 362.26 335.09 249.06 493.58 1.24 1.01 2.05 0.99 -0.10 Matched[5070]
YNR033W ABZ1 "Para-aminobenzoate (PABA) synthase, has similarity to Escherichia coli PABA synthase components PabA and PabB" Verified chr14:687637-690000 687637-690000 98.7% 113.61 89.17 99.03 93.03 188.21 192.07 101.39 96.03 190.14 0.37 0.39 0.79 0.99 1.39 Matched[5071]
YNR034W SOL1 "Protein with a possible role in tRNA export; shows similarity to 6-phosphogluconolactonase non-catalytic domains but does not exhibit this enzymatic activity; homologous to Sol2p, Sol3p, and Sol4p" Verified chr14:690323-691288 690323-691288 98.5% 107.25 98.84 134.59 104.10 432.16 340.68 103.04 119.34 386.42 0.38 0.48 1.60 1.70 1.93 Matched[5072]
YNR034W-A Putative protein of unknown function; expression is regulated by Msn2p/Msn4p Uncharacterized chr14:692563-692859 692563-692859 98.6% 180.99 1591.35 310.76 416.62 16091.07 8725.10 886.17 363.69 12408.08 3.27 1.48 51.41 5.09 2.66 Matched[5075]
YNR035C ARC35 "Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches; required for cortical localization of calmodulin" Verified chr14:693021-694049 693021-694049 98.8% 677.57 802.46 726.74 684.45 1659.00 1244.99 740.01 705.59 1452.00 2.73 2.86 6.02 1.04 1.03 Matched[5076]
YNR036C Mitochondrial protein; may interact with ribosomes based on co-purification experiments; similar to E. coli and human mitochondrial S12 ribosomal proteins Verified chr14:694363-694824 694363-694824 99.0% 806.78 843.95 1014.48 841.76 1394.92 892.05 825.36 928.12 1143.48 3.05 3.77 4.74 0.30 0.10 Matched[5077]
YNR037C RSM19 "Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S19 ribosomal protein" Verified chr14:695054-695329 695054-695329 98.7% 440.70 514.15 521.50 440.70 716.14 433.36 477.43 481.10 574.75 1.76 1.95 2.38 0.26 0.06 Matched[5078]
YNR038W DBP6 Essential protein involved in ribosome biogenesis; putative ATP-dependent RNA helicase of the DEAD-box protein family Verified chr14:695597-697486 695597-697486 99.0% 134.18 97.29 111.19 91.95 15.50 8.02 115.74 101.57 11.76 0.43 0.41 0.05 -3.11 -2.43 Covered/w/another[5079]
YNR039C ZRG17 "Endoplasmic reticulum protein of unknown function, transcription is induced under conditions of zinc deficiency; mutant phenotype suggests a role in uptake of zinc" Verified chr14:697616-699433 697616-699433 98.8% 79.04 90.73 72.92 49.54 51.76 39.52 84.88 61.23 45.64 0.31 0.25 0.19 -0.42 0.20 Covered/w/another[5079]
YNR040W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr14:699692-700462 699692-700462 98.4% 89.62 105.43 134.42 101.48 127.83 68.53 97.52 117.95 98.18 0.36 0.48 0.41 -0.26 -0.05 Covered/w/another[5080]
YNR042W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps verified gene COQ2" Dubious chr14:701240-701668 701240-701668 98.9% 96.66 120.24 141.45 110.81 117.88 70.73 108.45 126.13 94.30 0.40 0.51 0.39 -0.42 -0.53 Covered/w/another[5080]
YNR041C COQ2 "Para hydroxybenzoate: polyprenyl transferase, catalyzes the second step in ubiquinone (coenzyme Q) biosynthesis" Verified chr14:700543-701661 700543-701661 98.7% 162.93 162.93 182.84 153.88 152.06 80.56 162.93 168.36 116.31 0.60 0.68 0.48 -0.53 -0.48 Covered/w/another[5080]
YNR043W MVD1 "Mevalonate pyrophosphate decarboxylase, essential enzyme involved in the biosynthesis of isoprenoids and sterols, including ergosterol; acts as a homodimer" Verified chr14:701897-703087 701897-703087 98.8% 463.07 402.75 429.09 414.64 181.83 172.48 432.91 421.87 177.16 1.60 1.71 0.73 -1.25 -0.65 Covered/w/another[5081]
YNR044W AGA1 "Anchorage subunit of a-agglutinin of a-cells, highly O-glycosylated protein with N-terminal secretion signal and C-terminal signal for addition of GPI anchor to cell wall, linked to adhesion subunit Aga2p via two disulfide bonds" Verified chr14:703701-705878 703701-705878 92.9% 446.18 507.45 539.57 410.61 79.06 38.05 476.82 475.09 58.55 1.76 1.93 0.24 -3.02 -2.47 Covered/w/another[5081]
YNR045W PET494 "Mitochondrial translational activator specific for the COX3 mRNA, acts together with Pet54p and Pet122p; located in the mitochondrial inner membrane" Verified chr14:706141-707610 706141-707610 98.6% 88.29 109.67 100.01 81.39 143.47 95.19 98.98 90.70 119.33 0.37 0.37 0.49 0.40 0.55 Covered/w/another[5081]
YNR046W TRM112 "Subunit of an adoMet-dependent tRNA methyltransferase (MTase) complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; putative zinc binding subunit of other MTase-related proteins" Verified chr14:707790-708197 707790-708197 98.5% 325.87 308.46 340.80 248.76 156.72 79.60 317.16 294.78 118.16 1.17 1.20 0.49 -1.32 -0.90 Covered/w/another[5081]
YNR047W "Putative protein kinase that, when overexpressed, interferes with pheromone-induced growth arrest; localizes to the cytoplasm; potential Cdc28p substrate" Uncharacterized chr14:708525-711206 708525-711206 98.3% 71.28 105.78 98.95 97.06 117.53 203.97 88.53 98.00 160.75 0.33 0.40 0.67 0.71 1.44 Matched[5082]
YNR048W "Protein proposed to interact with phospholipid translocases, shares similarity to Cdc50p" Verified chr14:711632-712813 711632-712813 98.9% 55.63 65.05 47.07 32.52 35.95 38.51 60.34 39.80 37.23 0.22 0.16 0.15 -0.10 -0.17 Matched[5084]
YNR049C MSO1 "Probable component of the secretory vesicle docking complex, acts at a late step in secretion; shows genetic and physical interactions with Sec1p and is enriched in microsomal membrane fractions; required for sporulation" Verified chr14:713025-713657 713025-713657 98.8% 155.12 140.72 139.13 126.33 217.48 103.94 147.92 132.73 160.71 0.55 0.54 0.67 0.28 0.32 Matched[5085]
YNR050C LYS9 "Saccharopine dehydrogenase (NADP+, L-glutamate-forming); catalyzes the formation of saccharopine from alpha-aminoadipate 6-semialdehyde, which is the seventh step in lysine biosynthesis pathway" Verified chr14:714050-715390 714050-715390 98.9% 603.66 548.64 576.52 510.21 266.03 222.32 576.15 543.36 244.18 2.13 2.21 1.01 -1.15 -0.44 Matched[5086]
YNR051C BRE5 "Ubiquitin protease cofactor, forms deubiquitination complex with Ubp3p that coregulates anterograde and retrograde transport between the endoplasmic reticulum and Golgi compartments; null is sensitive to brefeldin A" Verified chr14:716782-718329 716782-718329 99.1% 1098.02 927.29 815.21 745.48 518.06 400.11 1012.65 780.34 459.08 3.74 3.17 1.90 -0.77 -0.45 Frag<80[5088]
YNR052C POP2 "RNase of the DEDD superfamily, subunit of the Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation" Verified chr14:719348-720649 719348-720649 97.6% 258.15 253.43 267.59 280.97 214.07 154.26 255.79 274.28 184.17 0.94 1.11 0.76 -0.57 -0.47 Matched[5090]
YNR053C NOG2 Putative GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation Verified chr14:721122-723113 721122-721772,722304-723113 99.2% 494.95 303.74 214.69 158.77 23.47 26.92 399.34 186.73 25.20 1.47 0.76 0.10 -2.89 -3.43 Matched[5091]
YNR054C ESF2 "Essential nucleolar protein involved in pre-18S rRNA processing; component of the small subunit (SSU) processome; has sequence similarity to mABT1, a mouse transcription activator" Verified chr14:723357-724307 723357-724307 99.4% 190.51 150.29 161.93 125.95 13.76 14.82 170.40 143.94 14.29 0.63 0.58 0.06 -3.33 -2.81 Matched[5092]
YNR055C HOL1 Putative ion transporter similar to the major facilitator superfamily of transporters; mutations in membrane-spanning domains permit nonselective cation uptake Verified chr14:728427-730187 728427-730187 98.8% 236.79 256.33 204.03 190.81 230.47 155.18 246.56 197.42 192.83 0.91 0.80 0.80 -0.03 0.14 Matched[5096]
YNR056C BIO5 "Putative transmembrane protein involved in the biotin biosynthesis pathway; responsible for uptake of 7-keto 8-aminopelargonic acid; BIO5 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis" Verified chr14:731618-733303 731618-733303 98.8% 28.83 28.23 27.63 15.62 42.04 26.43 28.53 21.62 34.23 0.11 0.09 0.14 0.66 0.17 Covered/w/another[5097]
YNR057C BIO4 "Dethiobiotin synthetase, catalyzes the third step in the biotin biosynthesis pathway; BIO4 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis; expression appears to be repressed at low iron levels" Verified chr14:733356-734069 733356-734069 99.0% 31.13 53.76 19.81 16.98 42.45 26.88 42.45 18.39 34.66 0.16 0.07 0.14 0.91 0.26 Covered/w/another[5097]
YNR058W BIO3 "7,8-diamino-pelargonic acid aminotransferase (DAPA), catalyzes the second step in the biotin biosynthesis pathway; BIO3 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis" Verified chr14:734291-735733 734291-735733 98.7% 18.25 28.08 11.93 23.17 23.17 11.93 23.17 17.55 17.55 0.09 0.07 0.07 0.00 0.37
YNR059W MNT4 "Putative alpha-1,3-mannosyltransferase, not required for protein O-glycosylation" Verified chr14:736803-738545 736803-738545 98.8% 80.73 110.35 63.89 60.40 38.91 21.49 95.54 62.14 30.20 0.35 0.25 0.13 -1.04 -1.37 Matched[5099]
YNR060W FRE4 "Ferric reductase, reduces a specific subset of siderophore-bound iron prior to uptake by transporters; expression induced by low iron levels" Verified chr14:739951-742110 739951-742110 98.9% 21.07 22.47 24.81 11.70 34.64 26.69 21.77 18.26 30.67 0.08 0.07 0.13 0.75 0.59 Frag>80[5100,5101]
YNR061C Putative protein of unknown function Uncharacterized chr14:742881-743540 742881-743540 99.0% 373.28 302.91 310.56 273.84 234.06 113.21 338.09 292.20 173.64 1.25 1.19 0.72 -0.75 -0.84 Matched[5102]
YNR062C Putative membrane protein of unknown function Uncharacterized chr14:744360-745343 744360-745343 98.8% 51.41 37.02 47.30 35.99 32.90 35.99 44.22 41.65 34.45 0.16 0.17 0.14 -0.27 -0.61 Covered[5103]
YNR063W Putative zinc-cluster protein of unknown function Uncharacterized chr14:746943-748766 746943-748766 98.9% 19.40 19.95 9.42 6.10 6.10 0.55 19.67 7.76 3.32 0.07 0.03 0.01 -1.22 -0.79
YNR064C "Epoxide hydrolase, member of the alpha/beta hydrolase fold family; may have a role in detoxification of epoxides" Verified chr14:749136-750008 749136-750008 98.9% 30.11 20.84 33.58 16.21 25.48 13.90 25.48 24.90 19.69 0.09 0.10 0.08 -0.34 1.37
YNR065C Protein of unknown function; YNR065C is not an essential gene Uncharacterized chr14:750350-753700 750350-753700 51.8% 67.43 108.92 48.99 49.56 35.73 36.31 88.18 49.27 36.02 0.33 0.20 0.15 -0.45 -0.07 Frag<80[5104]
YNR066C Putative membrane-localized protein of unknown function Uncharacterized chr14:753725-755035 753725-755035 95.5% 23.16 37.54 17.57 20.77 7.99 19.17 30.35 19.17 13.58 0.11 0.08 0.06 -0.50 -0.14
YNR067C DSE4 "Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother" Verified chr14:755746-759099 755746-759099 98.9% 203.52 279.50 158.89 114.57 232.16 168.84 241.51 136.73 200.50 0.89 0.56 0.83 0.55 1.13 Covered/w/another[5105]
YNR068C Putative protein of unknown function Uncharacterized chr14:760067-760885 760067-760885 99.2% 38.15 61.53 66.45 39.38 238.74 211.67 49.84 52.92 225.21 0.18 0.21 0.93 2.09 2.74 Covered/w/another[5105]
YNR069C BSC5 "Protein of unknown function, ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression" Verified chr14:761123-762592 761123-762592 99.0% 14.43 37.11 19.24 21.30 90.02 134.00 25.77 20.27 112.01 0.10 0.08 0.46 2.47 3.07 Covered/w/another[5105]
YNR070W "Putative transporter of the ATP-binding cassette (ABC) family, implicated in pleiotropic drug resistance; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr14:765375-769376 765375-769376 98.9% 14.40 20.47 13.65 10.61 22.74 35.63 17.44 12.13 29.19 0.06 0.05 0.12 1.27 0.25 Frag>80[5106,5107]
YNR071C Putative protein of unknown function Uncharacterized chr14:770440-771468 770440-771468 99.0% 16.69 17.67 12.76 9.82 16.69 7.85 17.18 11.29 12.27 0.06 0.05 0.05 0.12 -0.01
YNR072W HXT17 "Hexose transporter, up-regulated in media containing raffinose and galactose at pH 7.7 versus pH 4.7, repressed by high levels of glucose" Verified chr14:772657-774351 772657-774351 19.6% 27.04 27.04 24.04 21.03 30.05 21.03 27.04 22.53 25.54 0.10 0.09 0.11 0.18 0.04
YNR073C Putative mannitol dehydrogenase Uncharacterized chr14:774792-776300 774792-776300 8.5% 15.59 31.18 7.79 7.79 0.00 23.38 23.38 7.79 11.69 0.09 0.03 0.05 0.58 0.55
YNR074C AIF1 "Mitochondrial cell death effector that translocates to the nucleus in response to apoptotic stimuli, homolog of mammalian Apoptosis-Inducing Factor, putative reductase" Verified chr14:777602-778738 777602-778738 99.1% 112.66 114.43 120.64 109.11 103.78 72.74 113.54 114.87 88.26 0.42 0.47 0.37 -0.38 -0.54 Matched[5108]
YNR075W COS10 "Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" Verified chr14:779916-781040 779916-781040 96.4% 46.11 113.44 30.43 27.67 16.60 18.45 79.78 29.05 17.52 0.29 0.12 0.07 -0.73 -0.32
YNR075C-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr14:781511-781603 781511-781603 22.9% 375.73 469.67 93.93 93.93 46.97 93.93 422.70 93.93 70.45 1.56 0.38 0.29 -0.42 NaN Matched[5109]
YNR076W PAU6 "Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme" Verified chr14:781918-782280 781918-782280 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.04
YNR077C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr14:783287-783541 783287-783541 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.67
YOL166W-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr15:585-740 585-740 48.5% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN NaN
YOL166C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr15:1000-1338 1000-1338 39.6% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN -0.21
YOL165C AAD15 Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role Verified chr15:1647-2078 1647-2078 16.9% 0.00 0.00 0.00 27.44 0.00 0.00 0.00 13.72 0.00 0.00 0.06 0.00 -Inf -1.33
YOL164W-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr15:4130-4312 4130-4312 99.7% 32.90 21.93 49.35 16.45 71.28 21.93 27.42 32.90 46.61 0.10 0.13 0.19 0.50 NaN Covered[5110]
YOL164W BDS1 Bacterially-derived sulfatase required for use of alkyl- and aryl-sulfates as sulfur sources Verified chr15:6175-8115 6175-8115 98.5% 60.16 72.19 63.30 48.13 52.84 30.87 66.18 55.72 41.85 0.24 0.23 0.17 -0.41 -0.18 Matched[5111]
YOL163W Putative protein of unknown function; member of the Dal5p subfamily of the major facilitator family Uncharacterized chr15:9596-10105 9596-10105 98.6% 7.96 9.95 21.88 9.95 19.89 19.89 8.95 15.91 19.89 0.03 0.06 0.08 0.32 1.07
YOL162W Putative protein of unknown function; member of the Dal5p subfamily of the major facilitator family Uncharacterized chr15:10118-10765 10118-10765 99.1% 6.23 6.23 10.90 7.79 29.60 14.02 6.23 9.35 21.81 0.02 0.04 0.09 1.22 0.98
YOL161C Hypothetical protein Uncharacterized chr15:11548-11910 11548-11910 11.6% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 0.11
YOL160W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr15:14312-14653 14312-14653 98.8% 2.96 8.88 2.96 11.84 14.79 11.84 5.92 7.40 13.32 0.02 0.03 0.06 0.85 -0.03 Matched[5112]
YOL159C-A Putative protein of unknown function; identified by sequence comparison with hemiascomycetous yeast species Uncharacterized chr15:15232-15504 15232-15504 99.4% 77.38 73.70 58.96 40.53 202.67 73.70 75.54 49.75 138.19 0.28 0.20 0.57 1.47 1.04 Covered[5113]
YOL159C Soluble protein of unknown function; deletion mutants are viable and have elevated levels of Ty1 retrotransposition and Ty1 cDNA Verified chr15:17280-17795 17280-17795 99.1% 86.01 111.43 93.83 72.33 191.58 140.75 98.72 83.08 166.16 0.36 0.34 0.69 1.00 0.93 Frag>80[5114,5115]
YOL158C ENB1 "Endosomal ferric enterobactin transporter, expressed under conditions of iron deprivation; member of the major facilitator superfamily; expression is regulated by Rcs1p and affected by chloroquine treatment" Verified chr15:19490-21310 19490-21310 98.7% 250.28 137.37 240.27 159.07 276.97 231.37 193.83 199.67 254.17 0.72 0.81 1.05 0.35 1.00 Frag>80[5116,5117]
YOL157C Putative protein of unknown function Uncharacterized chr15:22524-24293 22524-24293 6.6% 17.10 8.55 34.20 8.55 17.10 17.10 12.83 21.38 17.10 0.05 0.09 0.07 -0.32 0.04
YOL156W HXT11 "Putative hexose transporter that is nearly identical to Hxt9p, has similarity to major facilitator superfamily (MFS) transporters and is involved in pleiotropic drug resistance" Verified chr15:25272-26975 25272-26975 11.7% 35.10 25.07 15.04 5.01 30.08 20.05 30.08 10.03 25.07 0.11 0.04 0.10 1.32 0.07
YOL155W-A Identified by expression profiling and mass spectrometry Uncharacterized chr15:27083-27217 27083-27217 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YOL155C HPF1 Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines Verified chr15:28702-31605 28702-31605 70.9% 386.49 711.79 327.74 364.64 331.13 625.37 549.14 346.19 478.25 2.03 1.41 1.98 0.47 0.14 Frag<80[5119,5120]
YOL154W ZPS1 "Putative GPI-anchored protein; transcription is induced under low-zinc conditions, as mediated by the Zap1p transcription factor, and at alkaline pH" Verified chr15:34657-35406 34657-35406 99.0% 40.41 44.45 35.02 25.59 33.68 16.17 42.43 30.31 24.92 0.16 0.12 0.10 -0.28 0.17
YOL152W FRE7 Putative ferric reductase with similarity to Fre2p; expression induced by low copper levels Verified chr15:40747-42609 40747-42609 98.9% 31.48 12.49 34.74 16.83 24.97 13.03 21.98 25.78 19.00 0.08 0.10 0.08 -0.44 -0.32
YOL151W GRE2 "NADPH-dependent methylglyoxal reductase (D-lactaldehyde dehydrogenase); stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway" Verified chr15:43693-44721 43693-44721 98.7% 204.75 48.23 186.05 116.16 730.40 676.26 126.49 151.10 703.33 0.47 0.61 2.91 2.22 2.68 Matched[5124]
YOL150C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr15:44472-44783 44472-44783 99.0% 223.30 32.36 174.76 93.85 834.95 576.05 127.83 134.30 705.50 0.47 0.55 2.92 2.39 -0.37 Covered/w/another[5124]
YOL149W DCP1 "Subunit of the Dcp1p-Dcp2p decapping enzyme complex, which removes the 5' cap structure from mRNAs prior to their degradation; enhances the activity of catalytic subunit Dcp2p; regulated by DEAD box protein Dhh1p" Verified chr15:44937-45632 44937-45632 98.8% 334.38 311.12 273.32 261.69 184.64 106.13 322.75 267.51 145.38 1.19 1.09 0.60 -0.88 -1.12 Covered/w/another[5125]
YOL148C SPT20 "Subunit of the SAGA transcriptional regulatory complex, involved in maintaining the integrity of the complex" Verified chr15:45759-47573 45759-47573 99.2% 130.48 147.70 124.38 117.71 200.44 146.59 139.09 121.04 173.51 0.51 0.49 0.72 0.52 0.70 Covered/w/another[5125]
YOL147C PEX11 "Peroxisomal membrane protein required for peroxisome proliferation and medium-chain fatty acid oxidation, most abundant protein in the peroxisomal membrane, regulated by Adr1p and Pip2p-Oaf1p, promoter contains ORE and UAS1-like elements" Verified chr15:47932-48642 47932-48642 98.8% 182.17 145.17 148.02 129.51 116.71 56.93 163.67 138.77 86.82 0.60 0.56 0.36 -0.68 -0.90 Frag>80[5126,5127]
YOL146W PSF3 "Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery" Verified chr15:48863-49447 48863-49447 98.9% 162.51 153.87 152.14 105.46 160.78 77.80 158.19 128.80 119.29 0.58 0.52 0.49 -0.11 -0.44 Covered/w/another[5128]
YOL145C CTR9 "Component of the Paf1p complex, which is a large complex that binds to and modulates the activity of RNA polymerase II and is required for expression of a subset of genes, including cyclin genes; contains TPR repeats" Verified chr15:49554-52787 49554-52787 99.3% 236.64 211.42 220.13 212.04 122.37 114.58 224.03 216.09 118.47 0.83 0.88 0.49 -0.87 -0.42 Covered/w/another[5128]
YOL144W NOP8 Nucleolar protein required for 60S ribosomal subunit biogenesis Verified chr15:53097-54551 53097-54551 97.7% 151.32 95.01 91.50 58.42 35.19 19.71 123.17 74.96 27.45 0.45 0.30 0.11 -1.45 -2.16 Matched[5129]
YOL143C RIB4 "Lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, also known as DMRL synthase); catalyzes synthesis of immediate precursor to riboflavin" Verified chr15:54594-55103 54594-55103 98.6% 2431.21 2472.96 2488.86 2697.59 2709.52 2765.18 2452.08 2593.22 2737.35 9.05 10.53 11.34 0.08 0.19 Matched[5130]
YOL142W RRP40 Protein involved in rRNA processing; component of the exosome 3->5 exonuclease complex Verified chr15:55557-56279 55557-56279 98.7% 179.32 152.71 162.51 119.08 88.26 49.03 166.01 140.80 68.65 0.61 0.57 0.28 -1.04 -1.20 Matched[5131]
YOL141W PPM2 "Putative carboxymethyltransferase, similar to Ppm1p but biochemical activity not yet demonstrated; required for the synthesis of wybutosine, a modified guanosine found at the 3'-position adjacent to the anticodon of phe-tRNA" Verified chr15:56451-58538 56451-58538 98.9% 22.28 12.11 7.26 7.26 1.45 1.45 17.19 7.26 1.45 0.06 0.03 0.01 -2.32 -1.96
YOL140W ARG8 "Acetylornithine aminotransferase, catalyzes the fourth step in the biosynthesis of the arginine precursor ornithine" Verified chr15:58759-60030 58759-60030 98.7% 101.19 95.61 70.91 57.36 49.40 31.07 98.40 64.14 40.24 0.36 0.26 0.17 -0.67 -0.51 Matched[5132]
YOL139C CDC33 Cytoplasmic mRNA cap binding protein; the eIF4E-cap complex is responsible for mediating cap-dependent mRNA translation via interactions with the translation initiation factor eIF4G (Tif4631p or Tif4632p) Verified chr15:60383-61024 60383-61024 99.1% 2308.24 1712.71 2107.11 1992.41 917.64 521.67 2010.48 2049.76 719.65 7.42 8.32 2.98 -1.51 -2.08 Frag>80[5133,5134]
YOL138C "Putative protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the vacuole" Verified chr15:61325-65350 61325-65350 98.5% 69.83 77.64 58.48 48.15 47.39 36.80 73.73 53.32 42.10 0.27 0.22 0.17 -0.34 -0.15 Matched[5135]
YOL137W BSC6 Protein of unknown function containing 8 putative transmembrane seqments; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression Verified chr15:65621-67114 65621-67114 98.9% 94.78 108.32 64.32 55.52 60.26 37.91 101.55 59.92 49.08 0.37 0.24 0.20 -0.29 -0.58 Matched[5136]
YOL136C PFK27 "6-phosphofructo-2-kinase, catalyzes synthesis of fructose-2,6-bisphosphate; inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate, expression induced by glucose and sucrose, transcriptional regulation involves protein kinase A" Verified chr15:67561-68754 67561-68754 99.0% 166.69 209.84 137.08 136.23 68.54 53.31 188.27 136.65 60.92 0.69 0.55 0.25 -1.17 -0.33 Matched[5137]
YOL135C MED7 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation Verified chr15:69376-70044 69376-70044 98.9% 126.91 120.87 125.40 113.31 104.25 71.01 123.89 119.36 87.63 0.46 0.48 0.36 -0.45 0.22 Matched[5138]
YOL133W HRT1 "RING finger containing subunit of Skp1-Cullin-F-box ubiquitin protein ligases (SCF); required for Gic2p, Far1p, Sic1p and Cln2p degradation; may tether Cdc34p (a ubiquitin conjugating enzyme or E2) and Cdc53p (a cullin) subunits of SCF" Verified chr15:70325-70690 70325-70690 98.4% 386.07 372.18 366.62 377.73 744.36 516.61 379.12 372.18 630.48 1.40 1.51 2.61 0.76 0.71 Matched[5139]
YOL134C "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps HRT1, a verified gene that encodes an SCF ubiquitin ligase subunit" Dubious chr15:70156-70545 70156-70545 98.3% 247.77 279.07 229.52 252.99 539.88 310.37 263.42 241.25 425.12 0.97 0.98 1.76 0.82 0.01 Frag<80[5139]
YOL132W GAS4 "1,3-beta-glucanosyltransferase, involved with Gas2p in spore wall assembly; has similarity to Gas1p; localizes to the cell wall" Verified chr15:71300-72715 71300-72715 98.7% 9.30 4.29 6.44 6.44 12.16 11.44 6.80 6.44 11.80 0.03 0.03 0.05 0.87 0.91 Frag<80[5140]
YOL131W Putative protein of unknown function Uncharacterized chr15:73031-73357 73031-73357 98.5% 6.21 0.00 3.11 9.32 18.63 18.63 3.11 6.21 18.63 0.01 0.03 0.08 1.58 1.55 Overlap[5141]
YOL130W ALR1 "Plasma membrane Mg(2+) transporter, expression and turnover are regulated by Mg(2+) concentration; overexpression confers increased tolerance to Al(3+) and Ga(3+) ions" Verified chr15:74400-76979 74400-76979 95.6% 190.10 156.86 169.83 135.38 98.09 114.30 173.48 152.60 106.19 0.64 0.62 0.44 -0.52 0.26 Covered[5141]
YOL129W VPS68 Vacuolar membrane protein of unknown function involved in vacuolar protein sorting; also detected in the mitochondria Verified chr15:77560-78114 77560-78114 98.9% 887.27 1105.90 952.86 869.05 1741.74 1268.05 996.58 910.95 1504.90 3.68 3.70 6.24 0.72 0.53 Matched[5142]
YOL128C YGK3 "Protein kinase related to mammalian glycogen synthase kinases of the GSK-3 family; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation" Verified chr15:78352-79479 78352-79479 99.1% 33.09 28.62 32.20 17.89 17.89 13.42 30.86 25.04 15.65 0.11 0.10 0.06 -0.68 -0.81 Frag<80[5143]
YOL127W RPL25 "Primary rRNA-binding ribosomal protein component of the large (60S) ribosomal subunit, has similarity to E. coli L23 and rat L23a ribosomal proteins; binds to 26S rRNA via a conserved C-terminal motif" Verified chr15:80348-81190 80348-80360,80775-81190 98.9% 12094.28 9173.84 10387.74 8855.63 3045.37 2109.61 10634.06 9621.69 2577.49 39.26 39.06 10.68 -1.90 -2.84 Matched[5144]
YOL126C MDH2 "Cytoplasmic malate dehydrogenase, one of the three isozymes that catalyze interconversion of malate and oxaloacetate; involved in gluconeogenesis during growth on ethanol or acetate as carbon source; interacts with Pck1p and Fbp1p" Verified chr15:81787-82920 81787-82920 98.6% 590.10 624.97 641.06 683.98 473.87 484.60 607.53 662.52 479.23 2.24 2.69 1.99 -0.47 -0.17 Frag>80[5145,5146]
YOL125W TRM13 2'-O-methyltransferase responsible for modification of tRNA at position 4; exhibits no obvious similarity to other known methyltransferases Verified chr15:83834-85264 83834-85264 98.6% 145.24 124.70 92.81 92.11 21.96 25.51 134.97 92.46 23.74 0.50 0.38 0.10 -1.96 -2.63 Covered/w/another[5147]
YOL124C TRM11 "Catalytic subunit of an adoMet-dependent tRNA methyltransferase complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; contains a THUMP domain and a methyltransferase domain" Verified chr15:85456-86757 85456-86757 99.3% 160.15 87.42 92.84 58.03 9.28 22.44 123.79 75.43 15.86 0.46 0.31 0.07 -2.25 -3.55 Covered/w/another[5147]
YOL123W HRP1 "Subunit of cleavage factor I, a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences" Verified chr15:87844-89448 87844-89448 98.6% 838.37 623.57 617.25 502.26 165.53 212.91 730.97 559.76 189.22 2.70 2.27 0.78 -1.56 -0.47 Covered/w/another[5149]
YOL122C SMF1 Divalent metal ion transporter with a broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal transport proteins Verified chr15:89692-91419 89692-91419 99.0% 221.56 287.03 206.36 180.05 232.08 154.33 254.29 193.20 193.20 0.94 0.78 0.80 0.00 0.24 Covered/w/another[5149]
YOL121C RPS19A "Protein component of the small (40S) ribosomal subunit, required for assembly and maturation of pre-40 S particles; mutations in human RPS19 are associated with Diamond Blackfan anemia; nearly identical to Rps19Bp" Verified chr15:92026-92850 92026-92440,92831-92850 60.7% 5249.17 3931.20 4646.99 3578.98 1071.80 840.78 4590.18 4112.99 956.29 16.94 16.70 3.96 -2.10 -2.31 Matched[5150]
YOL120C RPL18A "Protein component of the large (60S) ribosomal subunit, identical to Rpl18Bp and has similarity to rat L18 ribosomal protein; intron of RPL18A pre-mRNA forms stem-loop structures that are a target for Rnt1p cleavage leading to degradation" Verified chr15:93395-94402 93395-93843,94291-94402 45.9% 9235.85 7640.25 8106.11 6417.34 2212.88 1712.07 8438.05 7261.73 1962.47 31.15 29.48 8.13 -1.89 -2.96 Matched[5151]
YOL119C MCH4 "Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport" Verified chr15:94856-96361 94856-96361 99.0% 102.62 185.12 85.18 83.84 137.50 107.98 143.87 84.51 122.74 0.53 0.34 0.51 0.54 0.92 Covered/w/another[5153]
YOL118C "Dubious open reading frame, unlikely to encode a functional protein; based on available experimental and comparative sequence data" Dubious chr15:96608-96916 96608-96916 98.8% 16.37 65.48 22.92 26.19 62.21 78.58 40.93 24.56 70.40 0.15 0.10 0.29 1.52 1.16 Covered/w/another[5153]
YOL117W RRI2 Subunit of the COP9 signalosome (CSN) complex that cleaves the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; plays a role in the mating pheromone response Verified chr15:97551-99488 97551-99488 98.7% 37.64 48.62 50.72 61.17 172.54 160.51 43.13 55.94 166.53 0.16 0.23 0.69 1.57 1.83 Covered/w/another[5154]
YOL116W MSN1 "Transcriptional activator involved in regulation of invertase and glucoamylase expression, invasive growth and pseudohyphal differentiation, iron uptake, chromium accumulation, and response to osmotic stress; localizes to the nucleus" Verified chr15:99809-100957 99809-100957 98.7% 103.12 136.61 103.12 90.78 178.92 135.73 119.87 96.95 157.33 0.44 0.39 0.65 0.70 0.92 Covered/w/another[5154]
YOL115W PAP2 "Catalytic subunit of TRAMP (Trf4/Pap2p-Mtr4p-Air1p/2p), a nuclear poly (A) polymerase complex involved in RNA quality control; catalyzes polyadenylation of unmodified tRNAs, and snoRNA and rRNA precursors; disputed role as a DNA polymerase" Verified chr15:101475-103229 101475-103229 98.6% 160.62 176.22 131.15 114.40 68.75 76.27 168.42 122.78 72.51 0.62 0.50 0.30 -0.76 -0.45 Covered/w/another[5154]
YOL114C Putative protein of unknown function with similarity to human ICT1 and prokaryotic factors that may function in translation termination; YOL114C is not an essential gene Uncharacterized chr15:103317-103925 103317-103925 99.2% 38.08 43.05 39.74 34.77 105.97 36.43 40.57 37.26 71.20 0.15 0.15 0.30 0.93 0.74 Covered/w/another[5154]
YOL113W SKM1 Member of the PAK family of serine/threonine protein kinases with similarity to Ste20p and Cla4p; proposed to be a downstream effector of Cdc42p during polarized growth Verified chr15:104326-106293 104326-106293 98.7% 93.69 84.43 89.06 80.82 204.89 126.12 89.06 84.94 165.50 0.33 0.34 0.69 0.96 1.14 Covered/w/another[5154]
YOL112W MSB4 "GTPase-activating protein of the Ras superfamily that acts primarily on Sec4p, localizes to the bud site and bud tip, has similarity to Msb3p; msb3 msb4 double mutation causes defects in secretion and actin organization" Verified chr15:106710-108188 106710-108188 98.2% 217.52 198.94 173.47 170.03 114.96 70.90 208.23 171.75 92.93 0.77 0.70 0.39 -0.89 -0.51 Matched[5155]
YOL111C MDY2 Protein required for efficient mating; involved in shmoo formation and nuclear migration in the pre-zygote; associates with ribosomes and interacts with YOR164C; contains a ubiquitin-like (UBL) domain Verified chr15:108258-108896 108258-108896 98.8% 358.14 397.76 393.00 297.92 446.88 350.21 377.95 345.46 398.55 1.40 1.40 1.65 0.21 0.52 Matched[5156]
YOL110W SHR5 "Subunit of a palmitoyltransferase, composed of Shr5p and Erf2p, that adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; palmitoylation is required for Ras2p membrane localization" Verified chr15:109176-109889 109176-109889 98.1% 62.85 84.27 68.56 62.85 145.69 91.41 73.56 65.70 118.55 0.27 0.27 0.49 0.85 0.47 Matched[5157]
YOL109W ZEO1 Peripheral membrane protein of the plasma membrane that interacts with Mid2p; regulates the cell integrity pathway mediated by Pkc1p and Slt2p; the authentic protein is detected in a phosphorylated state in highly purified mitochondria Verified chr15:110297-110638 110297-110638 98.2% 6681.40 5090.73 5653.72 4646.89 7995.04 4548.59 5886.06 5150.30 6271.81 21.73 20.91 25.99 0.28 -1.63 Matched[5158]
YOL108C INO4 "Transcription factor required for derepression of inositol-choline-regulated genes involved in phospholipid synthesis; forms a complex, with Ino2p, that binds the inositol-choline-responsive element through a basic helix-loop-helix domain" Verified chr15:111431-111886 111431-111886 99.5% 132.19 163.04 132.19 138.80 180.67 134.40 147.62 135.50 157.53 0.54 0.55 0.65 0.22 0.05 Covered/w/another[5159]
YOL107W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and colocalizes in a punctate pattern with the early golgi/COPI vesicles; YOL107W is not an essential protein Uncharacterized chr15:112102-113130 112102-113130 99.3% 74.42 92.04 85.19 90.08 111.62 82.25 83.23 87.63 96.94 0.31 0.36 0.40 0.15 0.38 Covered/w/another[5159]
YOL106W "Dubious open reading frame, unlikely to encode a functional protein; based on available experimental and comparative sequence data" Dubious chr15:113226-113579 113226-113579 48.9% 28.88 40.43 11.55 11.55 28.88 5.78 34.66 11.55 17.33 0.13 0.05 0.07 0.58 -0.56 Overlap[5159]
YOL105C WSC3 "Partially redundant sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway involved in maintenance of cell wall integrity; involved in the response to heat shock and other stressors; regulates 1,3-beta-glucan synthesis" Verified chr15:114138-115808 114138-115808 90.3% 139.90 237.36 135.92 107.41 143.21 86.86 188.63 121.66 115.03 0.70 0.49 0.48 -0.08 0.34 Covered/w/another[5160]
YOL104C NDJ1 "Meiosis-specific telomere protein, required for bouquet formation, effective homolog pairing, ordered cross-over distribution (interference), sister chromatid cohesion at meiotic telomeres, and segregation of small chromosomes" Verified chr15:116396-117454 116396-117454 99.1% 68.61 176.29 52.41 39.07 72.42 53.36 122.45 45.74 62.89 0.45 0.19 0.26 0.46 0.93 Covered/w/another[5160]
YOL103W ITR2 "Myo-inositol transporter with strong similarity to the major myo-inositol transporter Itr1p, member of the sugar transporter superfamily; expressed constitutively" Verified chr15:124001-125830 124001-125830 98.4% 389.11 355.81 329.72 308.07 193.72 167.08 372.46 318.89 180.40 1.37 1.29 0.75 -0.82 -0.58 Matched[5163]
YOL102C TPT1 "tRNA 2'-phosphotransferase, catalyzes the final step in yeast tRNA splicing: the transfer of the 2'-PO(4) from the splice junction to NAD(+) to form ADP-ribose 1''-2''cyclic phosphate and nicotinamide" Verified chr15:125997-126689 125997-126689 99.2% 155.70 138.24 129.51 103.32 125.14 65.48 146.97 116.41 95.31 0.54 0.47 0.39 -0.29 -0.49 Matched[5164]
YOL101C IZH4 "Membrane protein involved in zinc metabolism, member of the four-protein IZH family, expression induced by fatty acids and altered zinc levels; deletion reduces sensitivity to excess zinc; possible role in sterol metabolism" Verified chr15:126982-127920 126982-127920 99.1% 16.12 441.72 26.87 23.64 22.57 11.82 228.92 25.26 17.20 0.85 0.10 0.07 -0.55 -0.90 Frag<80[5165]
YOL100W PKH2 "Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; redundant with Pkh1p" Verified chr15:129237-132482 129237-132482 98.9% 103.09 113.37 112.12 104.65 134.55 145.45 108.23 108.39 140.00 0.40 0.44 0.58 0.37 0.89 Matched[5166]
YOL099C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene PKH2/YOL100W; may interact with ribosomes" Dubious chr15:132017-132508 132017-132508 98.9% 176.70 203.41 162.31 152.04 328.74 205.46 190.05 157.18 267.10 0.70 0.64 1.11 0.76 0.34 Covered/w/another[5166]
YOL098C Putative metalloprotease Uncharacterized chr15:132725-135838 132725-135838 99.1% 242.12 194.15 204.19 209.06 115.71 141.96 218.13 206.63 128.84 0.81 0.84 0.53 -0.68 0.16 Matched[5167]
YOL097W-A Putative protein of unknown function; identified by expression profiling and mass spectrometry Uncharacterized chr15:136220-136405 136220-136405 98.6% 38.16 65.41 70.86 59.96 16.35 16.35 51.78 65.41 16.35 0.19 0.27 0.07 -2.00 NaN Matched[5168]
YOL097C WRS1 "Cytoplasmic tryptophanyl-tRNA synthetase, aminoacylates tryptophanyl-tRNA" Verified chr15:136527-137825 136527-137825 99.0% 863.75 702.82 757.24 721.48 284.55 232.46 783.28 739.36 258.50 2.89 3.00 1.07 -1.52 -0.89 Matched[5169]
YOL096C COQ3 "O-methyltransferase, catalyzes two different O-methylation steps in ubiquinone (Coenzyme Q) biosynthesis; component of a mitochondrial ubiquinone-synthesizing complex" Verified chr15:138107-139045 138107-139045 99.3% 116.92 134.08 137.30 144.81 299.28 222.04 125.50 141.06 260.66 0.46 0.57 1.08 0.89 0.96 Frag>80[5170,5171]
YOL095C HMI1 "Mitochondrial inner membrane localized ATP-dependent DNA helicase, required for the maintenance of the mitochondrial genome; not required for mitochondrial transcription; has homology to E. coli helicase uvrD" Verified chr15:139227-141347 139227-141347 99.2% 51.80 42.77 49.90 47.05 53.23 36.12 47.29 48.48 44.67 0.17 0.20 0.19 -0.12 0.06 Matched[5172]
YOL094C RFC4 "Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon" Verified chr15:141584-142555 141584-142555 99.1% 169.24 132.90 118.36 132.90 77.87 66.45 151.07 125.63 72.16 0.56 0.51 0.30 -0.80 -0.37 Matched[5173]
YOL093W TRM10 "tRNA methyltransferase, methylates the N-1 position of guanosine in tRNAs" Verified chr15:142815-143696 142815-143696 98.2% 184.79 160.54 177.86 135.13 38.11 34.65 172.67 156.50 36.38 0.64 0.64 0.15 -2.10 -1.60 Matched[5174]
YOL092W Putative protein of unknown function; predicted to contain six transmembrane domains and is 58% similar to the uncharacterized ORF YBR147W; deletion mutant has no detectable phenotype Uncharacterized chr15:144204-145130 144204-145130 99.1% 532.37 502.97 489.91 474.67 120.84 56.61 517.67 482.29 88.73 1.91 1.96 0.37 -2.44 -1.98 Matched[5175]
YOL091W SPO21 "Component of the meiotic outer plaque of the spindle pole body, involved in modifying the meiotic outer plaque that is required prior to prospore membrane formation" Verified chr15:145334-147163 145334-147163 99.0% 12.70 16.01 9.39 7.73 12.15 6.63 14.36 8.56 9.39 0.05 0.03 0.04 0.13 0.64
YOL090W MSH2 Protein that forms heterodimers with Msh3p and Msh6p that bind to DNA mismatches to initiate the mismatch repair process; contains a Walker ATP-binding motif required for repair activity; Msh2p-Msh6p binds to and hydrolyzes ATP Verified chr15:147382-150276 147382-150276 98.9% 167.72 148.51 160.04 143.61 159.34 143.96 158.12 151.83 151.65 0.58 0.62 0.63 -0.00 0.31 Matched[5176]
YOL089C HAL9 Putative transcription factor containing a zinc finger; overexpression increases salt tolerance through increased expression of the ENA1 (Na+/Li+ extrusion pump) gene while gene disruption decreases both salt tolerance and ENA1 expression Verified chr15:150398-153490 150398-153490 99.1% 53.19 62.98 49.93 50.58 58.74 46.01 58.09 50.26 52.38 0.21 0.20 0.22 0.06 0.05 Matched[5177]
YOL088C MPD2 "Member of the protein disulfide isomerase (PDI) family, exhibits chaperone activity; overexpression suppresses the lethality of a pdi1 deletion but does not complement all Pdi1p functions; undergoes oxidation by Ero1p" Verified chr15:153912-154745 153912-154745 99.1% 189.98 204.50 215.39 186.35 302.51 223.86 197.24 200.87 263.18 0.73 0.82 1.09 0.39 0.84 Frag>80[5178,5179]
YOL087C "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; deletion mutant is sensitive to various chemicals including phenanthroline, sanguinarine, and nordihydroguaiaretic acid" Uncharacterized chr15:155287-158637 155287-158637 99.1% 155.38 191.52 184.59 177.06 199.95 224.34 173.45 180.83 212.15 0.64 0.73 0.88 0.23 0.67 Frag>80[5180,5181]
YOL086W-A Putative protein of unknown function; identified by homology Uncharacterized chr15:159173-159445 159173-159445 98.2% 175.37 175.37 220.15 190.30 395.52 272.39 175.37 205.22 333.96 0.65 0.83 1.38 0.70 -0.07 Covered[5182]
YOL086C ADH1 "Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway" Verified chr15:159548-160594 159548-160594 73.9% 48105.91 52157.57 48777.53 44488.21 45307.07 33516.31 50131.74 46632.87 39411.69 185.06 189.29 163.30 -0.24 -1.91 Frag>80[5182,5183]
YOL085W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YOL085C" Dubious chr15:161579-161791 161579-161791 98.9% 0.00 9.49 9.49 18.98 161.36 71.19 4.75 14.24 116.27 0.02 0.06 0.48 3.03 NaN Covered/w/another[5184]
YOL085C "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the dubious gene YOL085W-A" Dubious chr15:161673-162014 161673-162014 98.8% 2.96 17.76 8.88 11.84 97.66 44.39 10.36 10.36 71.02 0.04 0.04 0.29 2.78 4.13 Covered/w/another[5184]
YOL084W PHM7 "Protein of unknown function, expression is regulated by phosphate levels; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole" Verified chr15:162356-165331 162356-165331 98.7% 5.45 9.87 7.83 6.47 325.50 256.38 7.66 7.15 290.94 0.03 0.03 1.21 5.35 4.32 Frag>80[5185,5186,5187]
YOL083W Hypothetical protein Uncharacterized chr15:165714-166952 165714-166952 98.8% 57.98 82.48 86.56 76.76 312.76 239.27 70.23 81.66 276.01 0.26 0.33 1.14 1.76 1.67 Frag>80[5188,5189]
YOL083C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; identified by expression profiling and mass spectrometry" Dubious chr15:166461-166601 166461-166601 98.6% 79.09 122.23 71.90 129.42 345.12 237.27 100.66 100.66 291.19 0.37 0.41 1.21 1.53 NaN Covered/w/another[5188]
YOL082W ATG19 "Protein involved in the cytoplasm-to-vacuole targeting pathway and in autophagy, recognizes cargo proteins and delivers them to the preautophagosomal structure for eventual engulfment by the autophagosome and degradation" Verified chr15:168727-169974 168727-169974 98.7% 245.94 351.46 288.15 315.75 605.52 594.97 298.70 301.95 600.24 1.10 1.23 2.49 0.99 1.39 Matched[5191]
YOL081W IRA2 "GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, has similarity to Ira1p and human neurofibromin" Verified chr15:171070-180309 171070-180309 99.0% 82.61 95.07 82.40 79.01 247.30 468.37 88.84 80.70 357.83 0.33 0.33 1.48 2.15 1.96 Frag>80[5193,5194]
YOL079W "Dubious open reading frame, unlikely to encode a functional protein; based on available experimental and comparative sequence data" Dubious chr15:181057-181455 181057-181455 99.4% 75.63 42.86 60.50 50.42 20.17 2.52 59.24 55.46 11.34 0.22 0.23 0.05 -2.29 0.01 Matched[5195]
YOL080C REX4 Putative RNA exonuclease possibly involved in pre-rRNA processing and ribosome assembly Verified chr15:180558-181427 180558-181427 99.3% 111.12 63.66 68.29 54.40 11.58 1.16 87.39 61.35 6.37 0.32 0.25 0.03 -3.27 -2.32 Matched[5195]
YOL078W AVO1 "Component of a membrane-bound complex containing the Tor2p kinase and other proteins, which may have a role in regulation of cell growth" Verified chr15:181682-185212 181682-185212 98.6% 57.42 57.42 38.47 44.50 31.29 34.16 57.42 41.49 32.73 0.21 0.17 0.14 -0.34 0.02 Frag>80[5196,5197]
YOL077W-A ATP19 "Subunit k of the mitochondrial F1F0 ATP synthase, which is a large enzyme complex required for ATP synthesis; associated only with the dimeric form of ATP synthase" Verified chr15:185438-185644 185438-185644 98.5% 607.97 612.87 598.16 813.89 1328.70 632.48 610.42 706.03 980.59 2.25 2.87 4.06 0.47 -0.57 Matched[5197]
YOL077C BRX1 "Nucleolar protein, constituent of 66S pre-ribosomal particles; depletion leads to defects in rRNA processing and a block in the assembly of large ribosomal subunits; possesses a sigma(70)-like RNA-binding motif" Verified chr15:185848-186723 185848-186723 99.2% 610.90 292.22 411.87 292.22 33.36 4.60 451.56 352.04 18.98 1.67 1.43 0.08 -4.21 -4.19 Matched[5198]
YOL076W MDM20 "Non-catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes N-acetylation of proteins with specific N-terminal sequences; involved in mitochondrial inheritance and actin assembly" Verified chr15:187024-189414 187024-189414 99.0% 193.00 156.68 148.66 130.92 92.49 63.35 174.84 139.79 77.92 0.65 0.57 0.32 -0.84 -0.74 Matched[5199]
YOL075C Putative ABC transporter Uncharacterized chr15:189658-193542 189658-193542 99.1% 42.84 63.61 35.31 30.38 36.87 52.19 53.23 32.84 44.53 0.20 0.13 0.18 0.44 0.30 Matched[5200]
YOL073C Putative protein of unknown function Uncharacterized chr15:193832-194800 193832-194800 98.7% 112.90 171.44 174.57 172.48 280.15 209.07 142.17 173.53 244.61 0.52 0.70 1.01 0.50 0.81 Matched[5201]
YOL072W THP1 "Nuclear pore-associated protein, forms a complex with Sac3p that is involved in transcription and in mRNA export from the nucleus; contains a PAM domain implicated in protein-protein binding" Verified chr15:194970-196337 194970-196337 98.9% 70.94 70.94 60.60 59.86 94.59 79.81 70.94 60.23 87.20 0.26 0.24 0.36 0.53 0.99 Matched[5202]
YOL071W EMI5 "Non-essential protein of unknown function required for transcriptional induction of the early meiotic-specific transcription factor IME1, also required for sporulation" Verified chr15:196507-196995 196507-196995 98.4% 218.18 251.43 284.68 245.19 702.34 444.68 234.81 264.94 573.51 0.87 1.08 2.38 1.11 1.06 Matched[5203]
YOL070C "Protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, and bud neck; potential Cdc28p substrate" Verified chr15:197220-198725 197220-198725 99.0% 257.60 246.86 219.36 189.84 207.95 150.93 252.23 204.60 179.44 0.93 0.83 0.74 -0.19 0.07 Matched[5204]
YOL069W NUF2 "Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering" Verified chr15:198942-200297 198942-200297 98.8% 126.94 120.97 123.21 115.74 102.30 81.39 123.96 119.48 91.85 0.46 0.48 0.38 -0.38 -0.02 Matched[5205]
YOL068C HST1 NAD(+)-dependent histone deacetylase; essential subunit of the Sum1p/Rfm1p/Hst1p complex required for ORC-dependent silencing and mitotic repression; non-essential subunit of the Set3C deacetylase complex; involved in telomere maintenance Verified chr15:200368-201879 200368-201879 99.1% 468.31 462.98 388.26 382.25 408.27 251.50 465.64 385.26 329.89 1.72 1.56 1.37 -0.22 -0.01 Matched[5206]
YOL067C RTG1 "Transcription factor (bHLH) involved in interorganelle communication between mitochondria, peroxisomes, and nucleus" Verified chr15:201985-202518 201985-202518 98.9% 138.19 153.34 115.48 92.76 123.05 106.01 145.76 104.12 114.53 0.54 0.42 0.47 0.14 0.68 Covered/w/another[5206]
YOL066C RIB2 "DRAP deaminase, catalyzes the third step of the riboflavin biosynthesis pathway; cytoplasmic tRNA pseudouridine synthase involved in pseudouridylation of cytoplasmic tRNAs at position 32" Verified chr15:202696-204471 202696-204471 99.1% 146.64 127.88 102.87 85.82 119.92 120.49 137.26 94.35 120.21 0.51 0.38 0.50 0.35 0.83 Covered/w/another[5207]
YOL065C INP54 "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase with a role in secretion, localizes to the endoplasmic reticulum via the C-terminal tail; lacks the Sac1 domain and proline-rich region found in the other 3 INP proteins" Verified chr15:204731-205885 204731-205885 99.2% 107.36 140.52 108.23 93.39 184.17 166.71 123.94 100.81 175.44 0.46 0.41 0.73 0.80 1.05 Covered/w/another[5207]
YOL064C MET22 "Bisphosphate-3'-nucleotidase, involved in salt tolerance and methionine biogenesis; dephosphorylates 3'-phosphoadenosine-5'-phosphate and 3'-phosphoadenosine-5'-phosphosulfate, intermediates of the sulfate assimilation pathway" Verified chr15:206103-207176 206103-207176 99.1% 339.10 461.21 357.89 304.34 259.26 154.05 400.16 331.12 206.65 1.48 1.34 0.86 -0.68 -0.50 Matched[5208]
YOL063C CRT10 Protein involved in transcriptional regulation of RNR2 and RNR3; expression of the gene is induced by DNA damage and null mutations confer increased resistance to hydroxyurea; N-terminal region has a leucine repeat and a WD40 repeat Verified chr15:207392-210265 207392-210265 99.1% 73.05 74.81 72.35 68.84 91.67 84.99 73.93 70.59 88.33 0.27 0.29 0.37 0.32 0.88 Frag>80[5209]
YOL062C APM4 Mu2-like subunit of the clathrin associated protein complex (AP-2); involved in vesicle transport Verified chr15:210520-211995 210520-211995 99.1% 230.41 242.72 234.52 194.18 216.06 149.05 236.57 214.35 182.55 0.87 0.87 0.76 -0.23 -0.07 Matched[5210]
YOL061W PRS5 "5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes" Verified chr15:212244-213734 212244-213734 98.7% 521.89 394.13 441.02 370.35 135.91 113.48 458.01 405.69 124.70 1.69 1.65 0.52 -1.70 -1.20 Covered/w/another[5211]
YOL060C MAM3 "Protein required for normal mitochondrial morphology, has similarity to hemolysins" Verified chr15:214017-216137 214017-216137 98.7% 189.25 226.52 261.89 204.54 288.17 302.99 207.89 233.21 295.58 0.77 0.95 1.22 0.34 1.63 Covered/w/another[5211]
YOL059W GPD2 "NAD-dependent glycerol 3-phosphate dehydrogenase, homolog of Gpd1p, expression is controlled by an oxygen-independent signaling pathway required to regulate metabolism under anoxic conditions; located in cytosol and mitochondria" Verified chr15:217126-218448 217126-218448 98.6% 347.28 431.61 354.95 348.05 394.05 430.84 389.45 351.50 412.44 1.44 1.43 1.71 0.23 0.92 Covered/w/another[5211]
YOL058W ARG1 "Arginosuccinate synthetase, catalyzes the formation of L-argininosuccinate from citrulline and L-aspartate in the arginine biosynthesis pathway; potential Cdc28p substrate" Verified chr15:219210-220472 219210-220472 98.7% 87.44 557.51 80.22 99.47 70.59 49.73 322.47 89.84 60.16 1.19 0.36 0.25 -0.58 -1.31 Matched[5212]
YOL057W Putative metalloprotease Uncharacterized chr15:220766-222901 220766-222901 98.8% 262.86 259.55 266.18 231.13 236.81 224.97 261.20 248.65 230.89 0.96 1.01 0.96 -0.11 0.40 Matched[5213]
YOL056W GPM3 "Homolog of Gpm1p phosphoglycerate mutase, which converts 3-phosphoglycerate to 2-phosphoglycerate in glycolysis; may be non-functional derivative of a gene duplication event" Verified chr15:223267-224178 223267-224178 98.5% 160.22 196.94 179.14 180.25 120.17 72.32 178.58 179.69 96.24 0.66 0.73 0.40 -0.90 -0.77 Matched[5214]
YOL055C THI20 Multifunctional protein with both hydroxymethylpyrimidine kinase and thiaminase activities; involved in thiamine biosynthesis and also in thiamine degradation; member of a gene family with THI21 and THI22; functionally redundant with Thi21p Verified chr15:224419-226074 224419-226074 96.7% 58.06 61.18 55.57 50.57 136.73 66.80 59.62 53.07 101.77 0.22 0.22 0.42 0.94 1.15 Matched[5215]
YOL054W PSH1 "Nuclear protein, putative RNA polymerase II elongation factor; isolated as Pob3p/Spt16p-binding protein" Uncharacterized chr15:228613-229833 228613-229833 98.1% 81.83 64.30 59.29 47.60 26.72 33.40 73.06 53.44 30.06 0.27 0.22 0.12 -0.83 -0.60 Matched[5217]
YOL053W Putative protein of unknown function; YOL053W is not an essential gene Uncharacterized chr15:230084-231271 230084-231271 98.5% 99.16 92.32 134.21 147.03 237.65 134.21 95.74 140.62 185.93 0.35 0.57 0.77 0.40 0.41 Matched[5218]
YOL052C-A DDR2 "Multistress response protein, expression is activated by a variety of xenobiotic agents and environmental or physiological stresses" Verified chr15:231569-231754 231569-231754 98.2% 54.74 273.72 202.55 251.82 12925.18 7500.00 164.23 227.19 10212.59 0.61 0.92 42.31 5.49 3.61 Matched[5219]
YOL052C SPE2 "S-adenosylmethionine decarboxylase, required for the biosynthesis of spermidine and spermine; cells lacking Spe2p require spermine or spermidine for growth in the presence of oxygen but not when grown anaerobically" Verified chr15:232445-233635 232445-233635 98.7% 177.83 149.75 159.11 134.43 65.52 57.01 163.79 146.77 61.26 0.60 0.60 0.25 -1.26 -0.61 Matched[5220]
YOL051W GAL11 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors Verified chr15:234939-238184 234939-238184 96.3% 192.68 180.84 186.28 158.43 114.58 132.19 186.76 172.36 123.39 0.69 0.70 0.51 -0.48 0.14 Matched[5221]
YOL050C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps verified gene GAL11; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)" Dubious chr15:237881-238201 237881-238201 98.8% 290.22 302.84 302.84 170.35 246.06 126.18 296.53 236.59 186.12 1.09 0.96 0.77 -0.35 0.25 Covered/w/another[5221]
YOL049W GSH2 "Glutathione synthetase, catalyzes the ATP-dependent synthesis of glutathione (GSH) from gamma-glutamylcysteine and glycine; induced by oxidative stress and heat shock" Verified chr15:238618-240093 238618-240093 98.8% 426.02 407.50 400.64 407.50 404.76 334.78 416.76 404.07 369.77 1.54 1.64 1.53 -0.13 0.31 Matched[5222]
YOL048C Putative protein of unknown function Uncharacterized chr15:240203-241309 240203-240946,241025-241309 99.1% 161.82 228.52 224.59 244.21 711.05 360.92 195.17 234.40 535.98 0.72 0.95 2.22 1.19 0.94 Matched[5223]
YOL047C Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern Uncharacterized chr15:241613-242746 241613-242440,242504-242746 98.5% 15.17 16.12 20.86 26.55 391.61 231.36 15.65 23.71 311.49 0.06 0.10 1.29 3.72 1.10 Frag>80[5224,5225]
YOL045W PSK2 "One of two (see also PSK1) PAS domain containing S/T protein kinases; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation)" Verified chr15:243496-246801 243496-246801 98.7% 114.96 78.79 87.68 78.48 67.44 80.62 96.87 83.08 74.03 0.36 0.34 0.31 -0.17 0.28 Matched[5226]
YOL046C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data;almost completely overlaps the verified gene PSK2/YOL045W" Dubious chr15:243465-244139 243465-244139 99.0% 80.77 38.89 65.81 62.82 20.94 50.85 59.83 64.32 35.90 0.22 0.26 0.15 -0.84 0.08 Covered/w/another[5226]
YOL044W PEX15 "Phosphorylated tail-anchored type II integral peroxisomal membrane protein required for peroxisome biogenesis, cells lacking Pex15p mislocalize peroxisomal matrix proteins to cytosol, overexpression results in impaired peroxisome assembly" Verified chr15:247149-248300 247149-248300 99.0% 67.54 69.30 56.14 48.25 60.53 36.84 68.42 52.19 48.68 0.25 0.21 0.20 -0.10 0.33 Covered/w/another[5227]
YOL043C NTG2 "DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision repair, localizes to the nucleus" Verified chr15:248391-249533 248391-249533 99.3% 60.82 87.26 74.92 65.22 104.89 57.29 74.04 70.07 81.09 0.27 0.28 0.34 0.21 0.47 Covered/w/another[5227]
YOL042W NGL1 "Putative endonuclease, has a domain similar to a magnesium-dependent endonuclease motif in mRNA deadenylase Ccr4p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr15:249824-250915 249824-250915 98.8% 91.73 113.96 102.85 79.68 145.47 104.70 102.85 91.26 125.08 0.38 0.37 0.52 0.45 0.09 Matched[5228]
YOL041C NOP12 "Nucleolar protein, required for pre-25S rRNA processing; contains an RNA recognition motif (RRM) and has similarity to Nop13p, Nsr1p, and putative orthologs in Drosophila and S. pombe" Verified chr15:251266-252645 251266-252645 99.3% 375.67 215.92 253.85 193.31 26.99 9.48 295.80 223.58 18.24 1.09 0.91 0.08 -3.62 -3.72 Matched[5229]
YOL040C RPS15 Protein component of the small (40S) ribosomal subunit; has similarity to E. coli S19 and rat S15 ribosomal proteins Verified chr15:253148-253576 253148-253576 98.8% 11061.85 9749.63 10257.06 8557.77 2832.14 2258.63 10405.74 9407.41 2545.38 38.41 38.19 10.55 -1.89 -3.21 Matched[5230]
YOL039W RPP2A "Ribosomal protein P2 alpha, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm" Verified chr15:254296-254616 254296-254616 89.9% 7305.70 6172.42 6622.96 5437.69 2190.32 1822.96 6739.06 6030.33 2006.64 24.88 24.48 8.31 -1.59 -2.06 Matched[5231]
YOL038C-A Putative protein of unknown function; identified by SAGE analysis Uncharacterized chr15:254925-255020 254925-255020 99.3% 41.94 31.45 94.36 83.88 346.00 262.12 36.70 89.12 304.06 0.14 0.36 1.26 1.77 NaN Matched[5232]
YOL038W PRE6 20S proteasome alpha-type subunit; green fluorescent protein (GFP)-fusion protein relocates from the cytosol to the mitochondrial outer surface upon oxidative stress Verified chr15:255336-256100 255336-256100 98.2% 956.81 823.73 884.95 855.67 1706.02 1113.83 890.27 870.31 1409.93 3.29 3.53 5.84 0.70 0.53 Matched[5233]
YOL036W Protein of unknown function; potential Cdc28p substrate Uncharacterized chr15:256744-259029 256744-259029 98.7% 179.97 185.29 156.92 143.18 213.66 223.86 182.63 150.05 218.76 0.67 0.61 0.91 0.54 0.93 Matched[5234]
YOL037C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YOL036W" Dubious chr15:256665-257018 256665-257018 98.7% 120.23 120.23 91.60 88.74 131.68 151.72 120.23 90.17 141.70 0.44 0.37 0.59 0.65 0.12 Covered/w/another[5234]
YOL035C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr15:258802-259104 258802-259104 98.6% 254.43 261.12 190.82 227.65 448.60 237.69 257.78 209.23 343.14 0.95 0.85 1.42 0.71 0.52 Covered/w/another[5234]
YOL034W SMC5 Structural maintenance of chromosomes (SMC) protein; essential subunit of the Mms21-Smc5-Smc6 complex; required for growth and DNA repair; S. pombe homolog forms a heterodimer with S. pombe Rad18p that is involved in DNA repair Verified chr15:259924-263205 259924-263205 98.6% 57.48 50.99 39.87 30.91 30.60 24.42 54.24 35.39 27.51 0.20 0.14 0.11 -0.36 0.49 Matched[5236]
YOL033W MSE1 "Mitochondrial glutamyl-tRNA synthetase, encoded by a nuclear gene" Verified chr15:263476-265086 263476-265086 98.6% 89.38 88.12 69.87 78.05 107.01 67.35 88.75 73.96 87.18 0.33 0.30 0.36 0.24 0.11 Matched[5237]
YOL032W OPI10 "Protein with a possible role in phospholipid biosynthesis, based on inositol-excreting phenotype of the null mutant and its suppression by exogenous choline" Verified chr15:265430-266170 265430-266170 98.6% 68.45 78.04 98.57 86.25 1192.47 848.83 73.25 92.41 1020.65 0.27 0.38 4.23 3.47 3.13 Matched[5238]
YOL031C SIL1 "Nucleotide exchange factor for the endoplasmic reticulum (ER) lumenal Hsp70 chaperone Kar2p, required for protein translocation into the ER; homolog of Yarrowia lipolytica SLS1; GrpE-like protein" Verified chr15:266265-267530 266265-267530 99.1% 210.41 180.92 187.29 155.41 321.19 197.66 195.66 171.35 259.42 0.72 0.70 1.07 0.60 0.86 Matched[5239]
YOL030W GAS5 "1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall" Verified chr15:268188-269642 268188-269642 99.0% 1033.39 1397.30 1084.09 1097.98 659.76 573.64 1215.35 1091.04 616.70 4.49 4.43 2.56 -0.82 -0.21 Matched[5240]
YOL029C Putative protein of unknown function; identified as interacting with Hsc82p and Hsp82p in high-throughput two-hybrid screens Uncharacterized chr15:269816-270421 269816-270421 99.2% 231.31 194.70 169.74 128.14 148.11 64.90 213.01 148.94 106.50 0.79 0.60 0.44 -0.48 -0.31 Covered/w/another[5241]
YOL028C YAP7 Putative basic leucine zipper (bZIP) transcription factor Verified chr15:270634-271371 270634-271371 99.2% 147.54 139.34 103.83 102.46 56.01 60.11 143.44 103.14 58.06 0.53 0.42 0.24 -0.83 -0.21 Covered/w/another[5241]
YOL027C MDM38 "Mitochondrial inner membrane protein, involved in membrane integration of a subset of mitochondrial proteins; required for K+/H+ exchange; associates with mitochondrial ribosomes; human ortholog Letm1 implicated in Wolf-Hirschhorn syndrome" Verified chr15:272004-273725 272004-273725 99.0% 441.14 475.17 352.56 370.75 251.66 252.25 458.15 361.65 251.96 1.69 1.47 1.04 -0.52 -0.12 Frag>80[5242,5243]
YOL026C MIM1 "Mitochondrial outer membrane protein, required for assembly of the translocase of the outer membrane (TOM) complex and thereby for mitochondrial protein import; N terminus is exposed to the cytosol: transmembrane segment is highly conserved" Verified chr15:274013-274354 274013-274354 98.7% 429.74 533.47 346.75 403.06 817.98 654.98 481.60 374.91 736.48 1.78 1.52 3.05 0.97 0.65 Matched[5244]
YOL025W LAG2 Protein involved in determination of longevity; LAG2 gene is preferentially expressed in young cells; overexpression extends the mean and maximum life span of cells Verified chr15:274958-276940 274958-276940 99.0% 42.77 53.47 45.32 39.72 89.11 77.91 48.12 42.52 83.51 0.18 0.17 0.35 0.97 1.27 Matched[5245]
YOL024W "Putative protein of unknown function, predicted to have thiol-disulfide oxidoreductase active site" Uncharacterized chr15:277087-277605 277087-277605 98.9% 3.89 11.68 3.89 3.89 1.95 1.95 7.79 3.89 1.95 0.03 0.02 0.01 -1.00 -0.41 Overlap[5245]
YOL023W IFM1 Mitochondrial translation initiation factor 2 Verified chr15:278057-280087 278057-280087 98.8% 84.75 79.77 75.28 78.27 100.21 96.72 82.26 76.78 98.46 0.30 0.31 0.41 0.36 0.63 Matched[5246]
YOL022C "Cytoplasmic protein of unknown function; essential gene in S288C, and non-essential with reduced growth rate in CEN.PK2" Uncharacterized chr15:280273-281499 280273-281499 99.2% 225.96 151.19 160.22 119.96 40.26 8.22 188.57 140.09 24.24 0.70 0.57 0.10 -2.53 -2.10 Matched[5247]
YOL021C DIS3 "Catalytic component of the exosome, involved in RNA processing and degradation; binds Gsp1p/Ran and enhances the GEF activity of Srm1p; implicated in mitotic control; homologous to the E. coli RNase R of the RNase II family" Verified chr15:282422-285427 282422-285427 99.0% 174.36 137.07 134.71 129.00 45.69 48.38 155.71 131.86 47.03 0.57 0.54 0.19 -1.49 -0.71 Matched[5248]
YOL020W TAT2 "High affinity tryptophan and tyrosine permease, overexpression confers FK506 resistance" Verified chr15:286173-287951 286173-287951 98.7% 218.66 214.68 229.48 174.25 154.32 100.79 216.67 201.86 127.55 0.80 0.82 0.53 -0.66 -0.57 Frag>80[5249,5250]
YOL019W-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr15:288421-288573 288421-288573 98.1% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN NaN
YOL019W Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole Uncharacterized chr15:288899-290554 288899-290554 98.8% 156.46 124.68 161.96 121.62 44.00 24.45 140.57 141.79 34.22 0.52 0.58 0.14 -2.05 -1.02 Covered/w/another[5251]
YOL018C TLG2 "Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds Vps45p, which prevents Tlg2p degradation and also facilitates t-SNARE complex formation" Verified chr15:290882-292075 290882-292075 99.4% 134.78 160.89 143.20 143.20 139.83 92.66 147.84 143.20 116.25 0.55 0.58 0.48 -0.30 -0.09 Covered/w/another[5251]
YOL017W ESC8 "Protein involved in telomeric and mating-type locus silencing, interacts with Sir2p and also interacts with the Gal11p, which is a component of the RNA pol II mediator complex" Verified chr15:292530-294674 292530-294674 98.6% 64.30 55.32 46.81 35.93 28.37 15.13 59.81 41.37 21.75 0.22 0.17 0.09 -0.93 -0.44 Matched[5252]
YOL016C CMK2 "Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to Cmk1p and mammalian Cam Kinase II" Verified chr15:294778-296121 294778-296121 99.3% 186.63 233.10 203.12 218.86 652.84 527.67 209.87 210.99 590.26 0.77 0.86 2.45 1.48 1.84 Frag>80[5253,5254]
YOL015W Hypothetical protein; null mutant displays increased levels of spontaneous Rad52 foci Uncharacterized chr15:297079-298839 297079-298839 98.9% 33.86 30.99 17.79 14.92 32.71 16.07 32.43 16.36 24.39 0.12 0.07 0.10 0.58 0.58 Frag<80[5255,5256]
YOL014W Putative protein of unknown function Uncharacterized chr15:299694-300068 299694-300068 98.7% 137.78 97.25 116.16 72.94 307.97 197.21 117.51 94.55 252.59 0.43 0.38 1.05 1.42 1.83 Frag>80[5257,5258]
YOL013W-B "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the long terminal repeat (LTR) of a Ty1 element" Dubious chr15:300691-300981 300691-300981 97.0% 0.00 0.00 3.54 3.54 24.80 7.09 0.00 3.54 15.95 0.00 0.01 0.07 2.17 NaN
YOL013W-A Putative protein of unknown function; identified by SAGE Uncharacterized chr15:301048-301239 301048-301239 71.7% 29.05 21.79 7.26 14.52 29.05 43.57 25.42 10.89 36.31 0.09 0.04 0.15 1.74 0.07 Matched[5259]
YOL013C HRD1 Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger Verified chr15:301381-303036 301381-303036 99.0% 111.58 159.75 145.73 142.68 262.80 188.41 135.67 144.20 225.60 0.50 0.59 0.93 0.65 1.13 Frag>80[5259,5260]
YOL012C HTZ1 "Histone variant H2AZ, exchanged for histone H2A in nucleosomes by the SWR1 complex; involved in transcriptional regulation through prevention of the spread of silent heterochromatin" Verified chr15:303580-303984 303580-303984 99.1% 782.55 795.02 827.41 757.63 670.40 476.01 788.79 792.52 573.21 2.91 3.22 2.37 -0.47 -0.40 Matched[5261]
YOL011W PLB3 Phospholipase B (lysophospholipase) involved in phospholipid metabolism; hydrolyzes phosphatidylinositol and phosphatidylserine and displays transacylase activity in vitro Verified chr15:305350-307410 305350-307410 98.8% 166.90 165.91 116.83 80.99 62.83 52.52 166.40 98.91 57.68 0.61 0.40 0.24 -0.78 0.27 Frag>80[5263,5264,5265]
YOL010W RCL1 "RNA terminal phosphate cyclase-like protein involved in rRNA processing at sites A0, A1, and A2; does not possess detectable RNA cyclase activity" Verified chr15:307939-309042 307939-309042 98.6% 130.44 105.64 101.05 106.56 10.10 7.35 118.04 103.80 8.73 0.44 0.42 0.04 -3.57 -3.15 Matched[5266]
YOL009C MDM12 "Mitochondrial outer membrane protein, required for transmission of mitochondria to daughter cells; component of the Mdm10-Mdm12-Mmm1 complex involved in import and assembly of outer membrane beta-barrel proteins" Verified chr15:309325-310140 309325-310140 99.3% 78.98 92.55 71.57 82.68 177.70 114.76 85.76 77.12 146.23 0.32 0.31 0.61 0.92 0.96 Covered/w/another[5267]
YOL008W COQ10 "Coenzyme Q binding protein, required for function of coenzyme Q in respiration by functioning in the delivery of Q6 to its proper location for electron transport, START domain protein with homologs in bacteria and eukaryotes" Verified chr15:310313-310936 310313-310936 99.0% 119.80 93.90 119.80 111.70 169.98 132.75 106.85 115.75 151.37 0.39 0.47 0.63 0.39 0.25 Covered/w/another[5267]
YOL007C CSI2 Protein of unknown function; green fluorescent protein (GFP)- fusion protein localizes to the mother side of the bud neck and the vacuole; YOL007C is not an essential gene Verified chr15:311343-312368 311343-312368 98.7% 299.06 200.36 245.76 190.49 49.35 34.55 249.71 218.13 41.95 0.92 0.89 0.17 -2.38 -1.99 Matched[5268]
YOL006C TOP1 "Topoisomerase I, nuclear enzyme that relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone; relaxes both positively and negatively supercoiled DNA; functions in replication, transcription, and recombination" Verified chr15:313079-315388 313079-315388 99.3% 248.58 206.72 174.44 123.42 130.83 85.48 227.65 148.93 108.16 0.84 0.60 0.45 -0.46 -0.14 Matched[5269]
YOL005C RPB11 RNA polymerase II subunit B12.5; part of central core; similar to Rpc19p and bacterial alpha subunit Verified chr15:315814-316176 315814-316176 98.7% 586.18 496.86 544.31 480.11 611.30 407.54 541.52 512.21 509.42 2.00 2.08 2.11 -0.01 -0.10 Matched[5270]
YOL004W SIN3 "Component of the Sin3p-Rpd3p histone deacetylase complex, involved in transcriptional repression and activation of diverse processes, including mating-type switching and meiosis; involved in the maintenance of chromosomal integrity" Verified chr15:316939-321549 316939-321549 98.7% 194.60 217.45 199.21 183.40 153.97 232.82 206.02 191.31 193.39 0.76 0.78 0.80 0.02 0.77 Frag>80[5271,5272]
YOL003C PFA4 "Palmitoyltransferase with autoacylation activity, required for palmitoylation of amino acid permeases containing a C-terminal Phe-Trp-Cys site; required for modification of Chs3p; member of the DHHC family of putative palmitoyltransferases" Verified chr15:321859-322995 321859-322995 99.0% 165.28 143.07 127.96 116.41 120.85 85.31 154.18 122.19 103.08 0.57 0.50 0.43 -0.25 -0.01 Matched[5273]
YOL002C IZH2 "Plasma membrane protein involved in zinc metabolism and osmotin-induced apoptosis; transcription regulated by Zap1p, zinc and fatty acid levels; similar to mammalian adiponectins; deletion increases sensitivity to elevated zinc" Verified chr15:323412-324365 323412-324365 99.1% 312.95 743.26 271.72 277.00 182.91 119.47 528.11 274.36 151.19 1.95 1.11 0.63 -0.86 -1.12 Frag>80[5274,5275]
YOL001W PHO80 "Cyclin, negatively regulates phosphate metabolism; Pho80p-Pho85p (cyclin-CDK complex) phosphorylates Pho4p and Swi5p; deletion of PHO80 leads to aminoglycoside supersensitivity; truncated form of PHO80 affects vacuole inheritance" Verified chr15:325250-326131 325250-326131 99.1% 109.87 94.99 86.98 67.53 88.13 58.37 102.43 77.25 73.25 0.38 0.31 0.30 -0.08 0.11 Matched[5276]
YOR001W RRP6 Exonuclease component of the nuclear exosome; contributes to the quality-control system that retains and degrades aberrant mRNAs in the nucleus Verified chr15:326833-329034 326833-329034 98.7% 174.30 122.79 115.89 103.47 26.21 25.29 148.54 109.68 25.75 0.55 0.45 0.11 -2.09 -1.51 Matched[5277]
YOR002W ALG6 "Alpha 1,3 glucosyltransferase, involved in transfer of oligosaccharides from dolichyl pyrophosphate to asparagine residues of proteins during N-linked protein glycosylation; mutations in human ortholog are associated with disease" Verified chr15:329418-331052 329418-331052 99.2% 415.12 464.47 357.76 366.39 291.76 238.09 439.80 362.08 264.93 1.62 1.47 1.10 -0.45 -0.13 Matched[5278]
YOR003W YSP3 Putative precursor to the subtilisin-like protease III Verified chr15:331456-332892 331456-332892 98.6% 43.07 49.43 33.19 43.07 156.05 105.91 46.25 38.13 130.98 0.17 0.15 0.54 1.78 1.33 Matched[5279]
YOR004W UTP23 "Essential nucleolar protein that is a component of the SSU (small subunit) processome involved in 40S ribosomal subunit biogenesis; has homology to PINc domain protein Fcf1p, although the PINc domain of Utp23p is not required for function" Verified chr15:333593-334357 333593-334357 98.4% 367.84 176.62 207.16 146.07 13.28 9.30 272.23 176.62 11.29 1.00 0.72 0.05 -3.97 -2.92 Matched[5280]
YOR005C DNL4 "DNA ligase required for nonhomologous end-joining (NHEJ), forms stable heterodimer with required cofactor Lif1p, interacts with Nej1p; involved in meiosis, not essential for vegetative growth" Verified chr15:334510-337344 334510-337344 99.2% 35.56 48.01 47.65 33.07 102.42 78.95 41.79 40.36 90.68 0.15 0.16 0.38 1.17 1.08 Matched[5281]
YOR006C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus Uncharacterized chr15:337681-338622 337681-338622 99.3% 192.44 153.95 177.47 129.36 131.50 87.67 173.19 153.41 109.58 0.64 0.62 0.45 -0.49 -1.24 Matched[5282]
YOR007C SGT2 "Glutamine-rich cytoplasmic protein of unknown function; contains tetratricopeptide (TPR) repeats, which often mediate protein-protein interactions; has similarity to human SGT, which is a cochaperone that negatively regulates Hsp70" Verified chr15:338939-339979 338939-339979 99.3% 1401.75 1103.79 1376.60 1292.43 4879.52 3609.34 1252.77 1334.52 4244.43 4.62 5.42 17.59 1.67 1.17 Frag>80[5283,5284,5285]
YOR008C SLG1 Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway involved in maintenance of cell wall integrity; involved in organization of the actin cytoskeleton; secretory pathway Wsc1p is required for the arrest of secretion response Verified chr15:341279-342415 341279-342415 98.8% 346.37 346.37 395.34 377.53 519.11 440.75 346.37 386.44 479.93 1.28 1.57 1.99 0.31 0.57 Matched[5286]
YOR008C-A "Putative protein of unknown function, includes a potential transmembrane domain; deletion results in slightly lengthened telomeres" Uncharacterized chr15:342858-343082 342858-343082 98.7% 4.50 4.50 4.50 4.50 0.00 9.01 4.50 4.50 4.50 0.02 0.02 0.02 0.00 -0.05
YOR008W-B "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr15:343929-344030 343929-344030 98.7% 29.79 29.79 49.65 9.93 9.93 0.00 29.79 29.79 4.96 0.11 0.12 0.02 -2.58 0.63
YOR009W TIR4 Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth; transcription is also induced by cold shock Verified chr15:344335-345798 344335-345798 74.7% 53.00 49.35 44.78 23.76 36.55 29.24 51.18 34.27 32.90 0.19 0.14 0.14 -0.06 0.43 Frag<80[5287]
YOR010C TIR2 Putative cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; transcription is induced by cold shock and anaerobiosis Verified chr15:346195-346950 346195-346950 85.7% 67.91 98.77 67.91 43.21 46.30 26.24 83.34 55.56 36.27 0.31 0.23 0.15 -0.62 1.07 Matched[5288]
YOR011W AUS1 "Transporter of the ATP-binding cassette family, involved in uptake of sterols and anaerobic growth" Verified chr15:349679-353863 349679-353863 99.0% 52.15 44.90 40.08 40.56 16.66 13.04 48.53 40.32 14.85 0.18 0.16 0.06 -1.44 -0.76 Frag>80[5290,5291]
YOR011W-A Putative protein of unknown function Uncharacterized chr15:355652-355858 355652-355858 99.0% 0.00 0.00 0.00 0.00 14.64 0.00 0.00 0.00 7.32 0.00 0.00 0.03 Inf NaN
YOR012W Putative protein of unknown function Uncharacterized chr15:356543-356956 356543-356956 98.6% 102.88 90.63 68.59 56.34 166.56 105.33 96.75 62.46 135.95 0.36 0.25 0.56 1.12 1.35 Matched[5292]
YOR013W Hypothetical protein; null mutant displays increased levels of spontaneous Rad52 foci Dubious chr15:356751-357221 356751-357221 98.6% 88.26 75.34 75.34 66.73 204.50 127.01 81.80 71.04 165.75 0.30 0.29 0.69 1.22 1.34 Matched[5292]
YOR014W RTS1 B-type regulatory subunit of protein phosphatase 2A (PP2A); homolog of the mammalian B' subunit of PP2A Verified chr15:357674-359947 357674-359947 98.9% 334.35 351.69 318.79 324.13 335.69 289.00 343.02 321.46 312.34 1.27 1.30 1.29 -0.04 0.50 Matched[5293]
YOR015W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr15:359993-360352 359993-360352 99.2% 532.09 473.28 445.27 417.27 663.71 369.66 502.68 431.27 516.69 1.86 1.75 2.14 0.26 0.42
YOR016C ERP4 "Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport" Verified chr15:360461-361084 360461-361084 99.0% 299.33 260.50 279.92 249.17 241.08 145.62 279.92 264.55 193.35 1.03 1.07 0.80 -0.45 -0.43 Matched[5294]
YOR017W PET127 "Protein with a role in mitochondrial RNA stability and/or processing, located in the mitochondrial membrane" Verified chr15:361412-363814 361412-363814 98.7% 78.43 74.63 75.47 68.31 69.57 59.03 76.53 71.89 64.30 0.28 0.29 0.27 -0.16 0.54 Frag>80[5295,5296]
YOR018W ROD1 "Membrane protein; overexpression confers resistance to the GST substrate o-dinitrobenzene as well as to zinc and calcium; contains 2 PY motifs, which are required for Rod1p interaction with Rsp5p, a hect-type ubiquitin ligase" Verified chr15:364369-366882 364369-366882 98.9% 69.16 78.01 79.21 67.95 164.05 145.56 73.58 73.58 154.80 0.27 0.30 0.64 1.07 0.99 Matched[5297]
YOR019W "Protein of unknown function that may interact with ribosomes, based on co-purification experiments" Verified chr15:368127-370319 368127-370319 98.6% 28.20 40.22 27.28 17.57 98.47 51.78 34.21 22.42 75.12 0.13 0.09 0.31 1.74 1.13 Matched[5298]
YOR020C HSP10 "Mitochondrial matrix co-chaperonin that inhibits the ATPase activity of Hsp60p, a mitochondrial chaperonin; involved in protein folding and sorting in the mitochondria; 10 kD heat shock protein with similarity to E. coli groES" Verified chr15:370524-370844 370524-370844 99.0% 2256.20 1655.17 2105.15 1828.24 21067.26 12206.11 1955.68 1966.70 16636.69 7.22 7.98 68.93 3.08 1.26 Matched[5299]
YOR020W-A "Putative protein of unknown function, conserved in A. gossypii; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr15:371685-371957 371685-371957 98.6% 393.99 602.14 464.61 438.59 1397.55 739.66 498.06 451.60 1068.61 1.84 1.83 4.43 1.24 NaN Matched[5301]
YOR021C Putative protein of unknown function; YOR021C is not an essential gene Uncharacterized chr15:372798-373439 372798-373439 99.4% 559.41 314.96 385.48 357.27 172.37 73.65 437.19 371.38 123.01 1.61 1.51 0.51 -1.59 -2.00 Matched[5303]
YOR022C "Protein with similarity to bovine phospholipase A1; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr15:373710-375857 373710-375857 99.1% 50.72 63.87 63.40 46.96 92.05 62.93 57.30 55.18 77.49 0.21 0.22 0.32 0.49 0.32 Matched[5304]
YOR023C AHC1 "Subunit of the Ada histone acetyltransferase complex, required for structural integrity of the complex" Verified chr15:376012-377712 376012-377712 98.8% 119.65 144.66 146.44 134.54 254.19 197.04 132.16 140.49 225.62 0.49 0.57 0.93 0.68 1.14 Matched[5305]
YOR024W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr15:377847-378170 377847-378170 98.8% 3.12 0.00 0.00 3.12 3.12 3.12 1.56 1.56 3.12 0.01 0.01 0.01 1.00 2.43 Overlap[5305,5306]
YOR025W HST3 "Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism" Verified chr15:378219-379562 378219-379562 98.6% 227.06 245.92 184.06 150.87 206.69 102.59 236.49 167.47 154.64 0.87 0.68 0.64 -0.11 0.55 Matched[5306]
YOR026W BUB3 "Kinetochore checkpoint WD40 repeat protein that localizes to kinetochores during prophase and metaphase, delays anaphase in the presence of unattached kinetochores; forms complexes with Mad1p-Bub1p and with Cdc20p, binds Mad2p and Mad3p" Verified chr15:379781-380806 379781-380806 98.9% 186.21 204.93 151.72 97.54 112.32 77.83 195.57 124.63 95.07 0.72 0.51 0.39 -0.39 -0.12 Matched[5307]
YOR027W STI1 "Hsp90 cochaperone, interacts with the Ssa group of the cytosolic Hsp70 chaperones; activates the ATPase activity of Ssa1p; homolog of mammalian Hop protein" Verified chr15:381053-382822 381053-382822 98.5% 628.08 417.00 699.20 741.65 9254.82 9870.85 522.54 720.42 9562.83 1.93 2.92 39.62 3.73 3.51 Matched[5308]
YOR028C CIN5 Basic leucine zipper transcriptional factor of the yAP-1 family that mediates pleiotropic drug resistance and salt tolerance; localizes constitutively to the nucleus Verified chr15:383533-384420 383533-384420 98.8% 63.84 39.90 117.42 128.82 739.85 745.55 51.87 123.12 742.70 0.19 0.50 3.08 2.59 3.17 Matched[5310]
YOR029W Dubious open reading frame unlikely to encode a functional protein; based on available experimental and comparative sequence data Dubious chr15:384600-384935 384600-384935 99.2% 6.00 9.00 6.00 6.00 9.00 12.01 7.50 6.00 10.51 0.03 0.02 0.04 0.81 2.61 Overlap[5310]
YOR030W DFG16 "Probable multiple transmembrane protein, involved in diploid invasive and pseudohyphal growth upon nitrogen starvation; required for accumulation of processed Rim101p" Verified chr15:386825-388684 386825-388684 99.0% 97.26 93.45 70.63 82.59 66.83 99.43 95.35 76.61 83.13 0.35 0.31 0.34 0.12 0.75 Matched[5313]
YOR031W CRS5 "Copper-binding metallothionein, required for wild-type copper resistance" Verified chr15:389213-389422 389213-389422 98.2% 126.06 421.82 135.76 189.09 785.45 324.85 273.94 162.42 555.15 1.01 0.66 2.30 1.77 1.59 Matched[5314]
YOR032C HMS1 Basic helix-loop-helix (bHLH) protein with similarity to myc-family transcription factors; overexpression confers hyperfilamentous growth and suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant Verified chr15:389771-391075 389771-391075 99.0% 41.81 73.56 59.62 45.68 89.04 82.85 57.68 52.65 85.95 0.21 0.21 0.36 0.71 0.94 Matched[5315]
YOR032W-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr15:392176-392376 392176-392376 99.3% 15.03 10.02 0.00 10.02 10.02 20.03 12.52 5.01 15.03 0.05 0.02 0.06 1.58 NaN Overlap[5316]
YOR033C EXO1 "5'-3' exonuclease and flap-endonuclease involved in recombination, double-strand break repair and DNA mismatch repair; member of the Rad2p nuclease family, with conserved N and I nuclease domains" Verified chr15:392416-394524 392416-394524 99.2% 108.48 119.95 93.66 71.68 111.35 69.77 114.21 82.67 90.56 0.42 0.34 0.38 0.13 0.45 Covered/w/another[5316]
YOR034C AKR2 Ankyrin repeat-containing protein similar to Akr1p; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; possibly involved in constitutive endocytosis of Ste3p Verified chr15:394837-397086 394837-397086 98.9% 79.51 81.76 56.60 47.17 53.46 41.33 80.63 51.88 47.39 0.30 0.21 0.20 -0.13 0.19 Covered/w/another[5316]
YOR034C-A Putative protein of unknown function; identified by expression profiling and mass spectrometry Uncharacterized chr15:397426-397668 397426-397668 98.8% 124.91 62.46 62.46 54.13 154.06 62.46 93.68 58.29 108.26 0.35 0.24 0.45 0.89 NaN Covered/w/another[5316]
YOR035C SHE4 "Protein containing a UCS (UNC-45/CRO1/SHE4) domain, binds to myosin motor domains to regulate myosin function; involved in endocytosis, polarization of the actin cytoskeleton, and asymmetric mRNA localization" Verified chr15:397735-400104 397735-400104 99.2% 74.41 91.00 81.22 85.47 125.87 151.38 82.71 83.34 138.62 0.31 0.34 0.57 0.73 1.48 Matched[5317]
YOR036W PEP12 "Target membrane receptor (t-SNARE) for vesicular intermediates traveling between the Golgi apparatus and the vacuole; controls entry of biosynthetic, endocytic, and retrograde traffic into the prevacuolar compartment; syntaxin" Verified chr15:400348-401214 400348-401214 98.3% 171.29 222.92 198.28 184.20 306.22 186.55 197.11 191.24 246.38 0.73 0.78 1.02 0.37 0.35 Frag>80[5318,5319]
YOR037W CYC2 "Mitochondrial peripheral inner membrane protein, contains a FAD cofactor in a domain exposed in the intermembrane space; exhibits redox activity in vitro; likely participates in ligation of heme to acytochromes c and c1 (Cyc1p and Cyt1p)" Verified chr15:401555-402655 401555-402655 98.8% 130.52 88.24 119.49 97.43 140.63 89.16 109.38 108.46 114.89 0.40 0.44 0.48 0.08 0.37 Covered/w/another[5320]
YOR038C HIR2 "Non-essential transcriptional corepressor involved in the cell cycle-regulated transcription of histone H2A, H2B, H3, and H4 genes; recruits Swi-Snf complexes to histone gene promoters; promotes heterochromatic gene silencing with Asf1p" Verified chr15:402761-405388 402761-405388 99.2% 82.11 75.20 75.20 59.47 61.77 45.66 78.66 67.34 53.72 0.29 0.27 0.22 -0.33 0.26 Covered/w/another[5320]
YOR039W CKB2 "Beta' regulatory subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKA2 and CKB1, the many substrates include transcription factors and all RNA polymerases" Verified chr15:405768-406544 405768-406544 98.9% 519.22 422.92 422.92 426.83 543.95 441.14 471.07 424.88 492.54 1.74 1.72 2.04 0.21 0.12 Matched[5321]
YOR040W GLO4 "Mitochondrial glyoxalase II, catalyzes the hydrolysis of S-D-lactoylglutathione into glutathione and D-lactate" Verified chr15:407064-407921 407064-407921 98.5% 87.58 102.97 89.95 92.32 195.29 165.70 95.28 91.13 180.49 0.35 0.37 0.75 0.99 0.88 Matched[5322]
YOR042W CUE5 "Protein containing a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" Verified chr15:408425-409660 408425-409660 98.1% 310.16 371.20 367.07 374.50 594.74 610.41 340.68 370.79 602.58 1.26 1.51 2.50 0.70 1.11 Matched[5324]
YOR041C "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 85% of ORF overlaps the uncharacterized gene CUE5; deletion in cyr1 mutant results in loss of stress resistance" Dubious chr15:408358-408789 408358-408789 98.0% 266.82 255.02 245.57 262.10 363.64 467.53 260.92 253.84 415.58 0.96 1.03 1.72 0.71 -0.02 Covered/w/another[5324]
YOR043W WHI2 "Protein required, with binding partner Psr1p, for full activation of the general stress response, possibly through Msn2p dephosphorylation; regulates growth during the diauxic shift; negative regulator of G1 cyclin expression" Verified chr15:410870-412330 410870-412330 98.7% 328.00 348.80 331.46 283.62 291.94 237.85 338.40 307.54 264.89 1.25 1.25 1.10 -0.22 0.06 Matched[5325]
YOR044W Putative protein of unknown function; green fluorescent protein (GFP)-fusion localizes to the ER; null mutant displays increased levels of spontaneous Rad52 foci Uncharacterized chr15:413007-413480 413007-413480 99.1% 153.34 240.66 134.17 108.62 195.94 112.88 197.00 121.39 154.41 0.73 0.49 0.64 0.35 0.04 Frag>80[5326,5327]
YOR045W TOM6 Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; promotes assembly and stability of the TOM complex Verified chr15:413852-414037 413852-414037 98.9% 1407.29 1227.98 1418.16 1363.82 1630.07 825.90 1317.64 1390.99 1227.98 4.86 5.65 5.09 -0.18 -0.81 Matched[5328]
YOR046C DBP5 Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family involved in mRNA export from the nucleus; involved in translation termination Verified chr15:414460-415908 414460-415908 99.2% 534.56 437.11 467.04 475.39 231.08 187.23 485.83 471.22 209.16 1.79 1.91 0.87 -1.17 -0.51 Matched[5329]
YOR047C STD1 "Protein involved in control of glucose-regulated gene expression; interacts with protein kinase Snf1p, glucose sensors Snf3p and Rgt2p, and TATA-binding protein Spt15p; acts as a regulator of the transcription factor Rgt1p" Verified chr15:416348-417682 416348-417682 99.1% 192.07 156.53 141.41 127.04 55.96 46.88 174.30 134.22 51.42 0.64 0.54 0.21 -1.38 -0.63 Matched[5330]
YOR048C RAT1 "Nuclear 5' to 3' single-stranded RNA exonuclease, involved in RNA metabolism, including rRNA and snRNA processing as well as mRNA transcription termination" Verified chr15:418631-421651 418631-421651 99.1% 197.79 139.66 158.04 136.99 37.42 32.41 168.73 147.51 34.91 0.62 0.60 0.14 -2.08 -1.48 Matched[5332]
YOR049C RSB1 Suppressor of sphingoid long chain base (LCB) sensitivity of an LCB-lyase mutation; putative integral membrane transporter or flippase that may transport LCBs from the cytoplasmic side toward the extracytoplasmic side of the membrane Verified chr15:422669-423733 422669-423733 98.9% 86.42 121.56 104.46 87.37 180.44 117.76 103.99 95.92 149.10 0.38 0.39 0.62 0.64 1.03 Covered/w/another[5333]
YOR050C Hypothetical protein Dubious chr15:424272-424619 424272-424619 98.3% 102.35 93.58 99.43 70.18 35.09 23.39 97.97 84.81 29.24 0.36 0.34 0.12 -1.54 -0.37 Covered/w/another[5333]
YOR051C "Nuclear protein that inhibits replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts" Uncharacterized chr15:424848-426086 424848-426086 99.3% 598.01 477.76 451.76 455.82 167.38 125.94 537.88 453.79 146.66 1.99 1.84 0.61 -1.63 -1.46 Matched[5334]
YOR052C "Nuclear protein of unknown function; expression induced by nitrogen limitation in a GLN3, GAT1-independent manner and by weak acid" Verified chr15:426774-427226 426774-427226 99.2% 246.94 286.99 398.22 329.25 4082.31 2275.86 266.96 363.74 3179.09 0.99 1.48 13.17 3.13 2.68 Matched[5336]
YOR053W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene VHS3/YOR054C" Dubious chr15:427819-428160 427819-428160 79.8% 238.13 223.48 205.16 205.16 564.19 413.98 230.80 205.16 489.09 0.85 0.83 2.03 1.25 0.69 Matched[5337]
YOR055W Dubious open reading frame unlikely to encode a functional protein; based on available experimental and comparative sequence data Dubious chr15:429480-429914 429480-429914 98.9% 60.42 90.63 74.36 90.63 181.25 197.52 75.52 82.49 189.39 0.28 0.33 0.78 1.20 0.30 Covered/w/another[5338]
YOR054C VHS3 "Functionally redundant (see also SIS2) inhibitory subunit of Ppz1p, a PP1c-related ser/thr protein phosphatase Z isoform; synthetically lethal with sis2; putative phosphopantothenoylcysteine decarboxylase involved in coenzyme A biosynthesis" Verified chr15:427835-429859 427835-429859 95.6% 123.42 152.86 128.59 136.33 330.51 255.11 138.14 132.46 292.81 0.51 0.54 1.21 1.14 0.89 Frag>80[5337,5338]
YOR056C NOB1 Essential nuclear protein involved in proteasome maturation and synthesis of 40S ribosomal subunits; required for cleavage of the 20S pre-rRNA to generate the mature 18S rRNA Verified chr15:430249-431628 430249-431628 99.2% 240.37 144.66 207.49 126.39 28.49 10.96 192.51 166.94 19.73 0.71 0.68 0.08 -3.08 -2.07 Matched[5339]
YOR057W SGT1 "Probable cochaperone, regulates activity of Cyr1p (adenylyl cyclase); involved in assembly of the kinetochore complex, associates with the SCF (Skp1p/Cdc53p/F box protein) ubiquitin ligase complex" Verified chr15:432188-433375 432188-433375 98.8% 247.14 240.32 202.83 173.85 181.52 187.49 243.73 188.34 184.50 0.90 0.76 0.76 -0.03 0.11 Covered/w/another[5340]
YOR058C ASE1 Mitotic spindle midzone localized microtubule-associated protein (MAP) family member; required for spindle elongation and stabilization; undergoes cell cycle-regulated degradation by anaphase promoting complex; potential Cdc28p substrate Verified chr15:433690-436347 433690-436347 99.3% 97.02 114.07 94.36 90.95 104.22 100.05 105.54 92.66 102.13 0.39 0.38 0.42 0.14 0.64 Covered/w/another[5340]
YOR059C Hypothetical protein Uncharacterized chr15:438908-440260 438908-440260 99.3% 156.99 194.94 143.60 139.14 231.40 161.46 175.97 141.37 196.43 0.65 0.57 0.81 0.47 0.72 Frag<80[5342]
YOR060C Protein of unknown function required for cell viability; deletion mutant harbors aberrant mitochondria Uncharacterized chr15:440392-441165 440392-441165 99.3% 78.10 89.81 65.08 63.78 70.29 83.31 83.96 64.43 76.80 0.31 0.26 0.32 0.25 1.05 Covered/w/another[5343]
YOR061W CKA2 "Alpha' catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKB1 and CKB2, the many substrates include transcription factors and all RNA polymerases" Verified chr15:441536-442555 441536-442555 98.8% 491.29 442.66 429.76 437.70 312.64 265.99 466.98 433.73 289.32 1.72 1.76 1.20 -0.58 -0.19 Matched[5344]
YOR062C Protein of unknown function; similar to YKR075Cp and Reg1p; expression regulated by glucose and Rgt1p; GFP-fusion protein is induced in response to the DNA-damaging agent MMS Uncharacterized chr15:442727-443533 442727-443533 98.9% 71.42 132.81 62.65 57.64 121.53 60.14 102.11 60.14 90.84 0.38 0.24 0.38 0.59 0.13 Matched[5345]
YOR063W RPL3 "Protein component of the large (60S) ribosomal subunit, has similarity to E. coli L3 and rat L3 ribosomal proteins; involved in the replication and maintenance of killer double stranded RNA virus" Verified chr15:444688-445851 444688-445851 98.5% 16167.81 13673.40 13839.17 10214.92 4078.81 2483.93 14920.60 12027.05 3281.37 55.08 48.82 13.60 -1.87 -1.76 Frag>80[5346,5347,5348,5349]
YOR064C YNG1 "Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3, has similarity to the human tumor suppressor ING1" Verified chr15:446081-446740 446081-446740 99.2% 119.08 151.14 129.76 91.60 170.98 116.02 135.11 110.68 143.50 0.50 0.45 0.59 0.37 0.05 Frag>80[5349,5350]
YOR065W CYT1 "Cytochrome c1, component of the mitochondrial respiratory chain; expression is regulated by the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex" Verified chr15:447441-448370 447441-448370 98.6% 742.74 921.61 965.24 1276.07 1497.48 1440.76 832.17 1120.65 1469.12 3.07 4.55 6.09 0.39 0.54 Matched[5351]
YOR066W Protein of unknown function; potential Cdc28p substrate; YOR066W is not an essential gene Uncharacterized chr15:449438-451327 449438-451327 98.9% 140.67 220.36 155.11 156.71 147.62 183.99 180.51 155.91 165.80 0.67 0.63 0.69 0.09 0.97 Matched[5352]
YOR067C ALG8 "Glucosyl transferase, involved in N-linked glycosylation; adds glucose to the dolichol-linked oligosaccharide precursor prior to transfer to protein during lipid-linked oligosaccharide biosynthesis; similar to Alg6p" Verified chr15:451731-453464 451731-453464 98.9% 304.93 269.94 272.28 248.96 136.43 88.62 287.44 260.62 112.53 1.06 1.06 0.47 -1.21 -0.89 Matched[5353]
YOR069W VPS5 Nexin-1 homolog required for localizing membrane proteins from a prevacuolar/late endosomal compartment back to the late Golgi apparatus; structural component of the retromer membrane coat complex; forms a retromer subcomplex with Vps17p Verified chr15:453770-455797 453770-455797 98.5% 130.67 130.67 139.18 132.17 156.70 135.17 130.67 135.67 145.94 0.48 0.55 0.60 0.11 0.43 Frag<80[5354]
YOR068C VAM10 Protein involved in vacuole morphogenesis; acts at an early step of homotypic vacuole fusion that is required for vacuole tethering Verified chr15:453871-454215 453871-454215 98.5% 97.12 82.40 91.23 88.29 103.00 88.29 89.76 89.76 95.65 0.33 0.36 0.40 0.09 0.14 Covered[5354]
YOR070C GYP1 "Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in vivo) and for Ypt1p, Sec4p, Ypt7p, and Ypt51p (in vitro); involved in vesicle docking and fusion" Verified chr15:455909-457822 455909-457822 98.9% 98.76 97.18 116.19 107.21 127.81 104.57 97.97 111.70 116.19 0.36 0.45 0.48 0.06 0.67 Matched[5355]
YOR071C THI71 Transporter of thiamine or related compound; shares sequence similarity to Thi7p; proposed to be involved in 5-fluorocytosine sensitivity Verified chr15:459482-461278 459482-461278 85.0% 94.26 115.21 84.44 84.44 58.26 47.78 104.73 84.44 53.02 0.39 0.34 0.22 -0.67 -0.19 Matched[5356]
YOR072W "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the dubious gene YOR072W-A; diploid deletion strains are methotrexate, paraquat and wortmannin sensitive" Dubious chr15:461504-461818 461504-461818 99.0% 35.28 28.87 25.66 12.83 16.04 12.83 32.08 19.25 14.43 0.12 0.08 0.06 -0.42 -0.17 Covered/w/another[5356]
YOR072W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YOR072W; originally identified by fungal homology and RT-PCR" Dubious chr15:461793-462041 461793-462041 98.1% 12.28 28.65 32.74 8.19 8.19 4.09 20.46 20.46 6.14 0.08 0.08 0.03 -1.74 NaN
YOR072W-B Putative protein of unknown function; identified by expression profiling and mass spectrometry Uncharacterized chr15:464471-464632 464471-464632 76.3% 16.19 8.09 8.09 16.19 0.00 16.19 12.14 12.14 8.09 0.04 0.05 0.03 -0.58 NaN Covered/w/another[5358]
YOR073W SGO1 "Component of the spindle checkpoint, involved in sensing lack of tension on mitotic chromosomes; protects centromeric Rec8p at meiosis I; required for accurate chromosomal segregation at meiosis II and for mitotic chromosome stability" Verified chr15:464773-466545 464773-466545 98.8% 135.88 143.31 137.03 132.46 92.49 61.66 139.59 134.74 77.08 0.52 0.55 0.32 -0.81 -0.50 Covered/w/another[5358]
YOR073W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially/completely overlaps the verified ORF CDC21/YOR074C; identified by RT-PCR" Dubious chr15:467392-467625 467392-467625 99.3% 202.37 137.78 202.37 150.70 94.73 94.73 170.08 176.53 94.73 0.63 0.72 0.39 -0.90 NaN Covered/w/another[5358]
YOR074C CDC21 "Thymidylate synthase, required for de novo biosynthesis of pyrimidine deoxyribonucleotides; expression is induced at G1/S" Verified chr15:466677-467591 466677-467591 99.2% 257.90 246.88 243.57 231.45 115.72 109.11 252.39 237.51 112.42 0.93 0.96 0.47 -1.08 -0.78 Covered/w/another[5358]
YOR075W UFE1 "t-SNARE required for ER membrane fusion and vesicular traffic, integral membrane protein that constitutes with Sec20p and Use1p the trimeric acceptor for R/v-SNAREs on Golgi-derived vesicles at the ER; part of Dsl1p complex" Verified chr15:468214-469254 468214-469254 98.8% 103.04 111.79 114.71 78.74 209.97 98.18 107.42 96.72 154.08 0.40 0.39 0.64 0.67 0.43 Covered/w/another[5360]
YOR076C SKI7 "Putative GTPase that mediates interactions via its N-terminus between the exosome and Ski complex (Ski2p, Ski3p, Ski8p) which operate in the 3'-to-5' mRNA-decay pathway; cytoplasmic protein required for degrading nonstop mRNAs" Verified chr15:469379-471622 469379-471622 99.2% 87.64 79.55 80.45 81.35 89.44 79.55 83.59 80.90 84.49 0.31 0.33 0.35 0.06 0.78 Covered/w/another[5360]
YOR077W RTS2 "Basic zinc-finger protein, similar to human and mouse Kin17 proteins which are chromatin-associated proteins involved in UV response and DNA replication" Verified chr15:471901-472599 471901-472599 98.3% 50.92 68.38 80.02 55.29 34.92 29.10 59.65 67.66 32.01 0.22 0.27 0.13 -1.08 -0.31 Matched[5361]
YOR078W BUD21 Component of small ribosomal subunit (SSU) processosome that contains U3 snoRNA; originally isolated as bud-site selection mutant that displays a random budding pattern Verified chr15:472727-473371 472727-473371 98.1% 330.26 279.69 278.11 232.29 94.81 39.50 304.98 255.20 67.16 1.13 1.04 0.28 -1.93 -1.75 Covered/w/another[5362]
YOR079C ATX2 "Golgi membrane protein involved in manganese homeostasis; overproduction suppresses the sod1 (copper, zinc superoxide dismutase) null mutation" Verified chr15:473477-474418 473477-474418 99.1% 126.39 109.26 152.10 89.98 68.55 59.98 117.83 121.04 64.27 0.43 0.49 0.27 -0.91 -0.76 Matched[5362]
YOR080W DIA2 "Origin-binding F-box protein that forms an SCF ubiquitin ligase complex with Skp1p and Cdc53p; plays a role in DNA replication, involved in invasive and pseudohyphal growth" Verified chr15:474554-476794 474554-476794 98.8% 91.65 92.10 87.13 69.52 59.14 40.63 91.87 78.33 49.89 0.34 0.32 0.21 -0.65 -0.51 Covered/w/another[5363]
YOR081C TGL5 Triacylglycerol lipase involved in TAG mobilization; localizes to lipid particles; potential Cdc28p substrate Verified chr15:476941-479190 476941-479190 98.1% 141.85 172.22 141.85 134.60 118.29 153.64 157.04 138.23 135.96 0.58 0.56 0.56 -0.02 0.66 Covered/w/another[5363]
YOR083W WHI5 "Repressor of G1 transcription that binds to SCB binding factor (SBF) at SCB target promoters in early G1; phosphorylation of Whi5p by the CDK, Cln3p/Cdc28p relieves repression and promoter binding by Whi5; periodically expressed in G1" Verified chr15:479535-480422 479535-480422 97.9% 81.64 66.69 72.44 90.84 65.54 90.84 74.17 81.64 78.19 0.27 0.33 0.32 -0.06 0.81 Covered/w/another[5363]
YOR082C "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the verified gene YOR083W" Dubious chr15:479298-479639 479298-479639 98.0% 47.75 38.80 47.75 32.83 50.73 74.61 43.27 40.29 62.67 0.16 0.16 0.26 0.64 0.49 Covered/w/another[5363]
YOR084W Putative lipase of the peroxisomal matrix; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance Verified chr15:480589-481752 480589-481752 98.4% 159.74 180.69 189.42 137.92 197.27 150.14 170.21 163.67 173.70 0.63 0.66 0.72 0.09 0.47 Covered/w/another[5363]
YOR085W OST3 "Gamma subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; Ost3p is important for N-glycosylation of a subset of proteins" Verified chr15:482035-483087 482035-483087 99.2% 719.85 691.13 681.56 611.68 517.87 529.36 705.49 646.62 523.61 2.60 2.62 2.17 -0.30 0.01 Matched[5364]
YOR086C TCB1 "Lipid-binding protein containing three calcium and lipid binding domains; non-tagged protein localizes to mitochondria and GFP-fusion protein localizes to the cell periphery; C-termini of Tcb1p, Tcb2p and Tcb3p interact" Verified chr15:483221-486781 483221-486781 99.2% 334.69 445.69 401.52 399.82 293.35 341.77 390.19 400.67 317.56 1.44 1.63 1.32 -0.34 0.09 Frag>80[5365]
YOR087W YVC1 "Vacuolar cation channel, mediates release of Ca(2+) from the vacuole in response to hyperosmotic shock" Verified chr15:487709-489736 487709-489736 98.8% 157.20 178.15 185.64 161.69 161.19 140.73 167.68 173.66 150.96 0.62 0.70 0.63 -0.20 0.31 Frag>80[5366,5367,5368]
YOR089C VPS21 GTPase required for transport during endocytosis and for correct sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog Verified chr15:490198-490830 490198-490830 99.3% 561.51 531.28 528.10 469.25 1256.63 941.68 546.39 498.67 1099.15 2.02 2.02 4.55 1.14 0.50 Frag>80[5368,5369]
YOR090C PTC5 Mitochondrially localized type 2C protein phosphatase involved in regulation of pyruvate dehydrogenase activity; contains Mg2+/Mn2+-dependent casein phosphatase activity in vitro Verified chr15:491125-492843 491125-492843 99.1% 216.69 223.74 219.04 198.49 253.69 233.14 220.22 208.76 243.41 0.81 0.85 1.01 0.22 0.65 Matched[5370]
YOR091W TMA46 Protein of unknown function that associates with ribosomes; interacts with GTPase Rbg1p Verified chr15:493434-494471 493434-494471 98.0% 324.27 188.67 244.68 194.56 56.01 35.38 256.47 219.62 45.69 0.95 0.89 0.19 -2.26 -2.03 Covered/w/another[5371]
YOR092W ECM3 Non-essential protein of unknown function Verified chr15:495128-496969 495128-496969 99.0% 181.49 203.98 194.11 125.02 134.34 103.08 192.73 159.56 118.71 0.71 0.65 0.49 -0.43 0.29 Covered/w/another[5371]
YOR093C Putative protein of unknown function; deletion causes sensitivity to unfolded protein response-inducing agents Uncharacterized chr15:497507-502453 497507-502453 99.3% 60.89 56.00 42.77 36.25 31.57 34.62 58.45 39.51 33.09 0.22 0.16 0.14 -0.26 -0.23 Frag>80[5372,5373]
YOR094W ARF3 "Glucose-repressible ADP-ribosylation factor, GTPase of the Ras superfamily involved in development of polarity" Verified chr15:502796-503347 502796-503347 98.6% 181.92 205.80 170.89 163.54 203.97 145.16 193.86 167.22 174.57 0.72 0.68 0.72 0.06 -0.17 Matched[5374]
YOR095C RKI1 "Ribose-5-phosphate ketol-isomerase, catalyzes the interconversion of ribose 5-phosphate and ribulose 5-phosphate in the pentose phosphate pathway; participates in pyridoxine biosynthesis" Verified chr15:503553-504329 503553-504329 99.3% 397.93 208.68 243.68 156.84 29.81 5.18 303.31 200.26 17.50 1.12 0.81 0.07 -3.52 -3.10 Matched[5375]
YOR096W RPS7A "Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Bp; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins" Verified chr15:505795-506768 505795-505938,506340-506768 80.8% 8435.00 6550.95 7622.61 6512.06 1525.39 1212.10 7492.98 7067.34 1368.74 27.66 28.69 5.67 -2.37 -2.36 Covered/w/another[5376]
YOR097C Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen; YOR097C is not an essential gene Uncharacterized chr15:506979-507506 506979-507506 99.4% 127.61 255.22 177.13 201.89 424.73 241.89 191.41 189.51 333.31 0.71 0.77 1.38 0.81 0.59 Covered/w/another[5376]
YOR098C NUP1 "Nuclear pore complex (NPC) subunit, involved in protein import/export and in export of RNAs, possible karyopherin release factor that accelerates release of karyopherin-cargo complexes after transport across NPC; potential Cdc28p substrate" Verified chr15:507949-511179 507949-511179 98.8% 173.31 134.45 131.63 126.92 55.78 66.75 153.88 129.27 61.27 0.57 0.52 0.25 -1.08 -0.22 Matched[5377]
YOR099W KTR1 "Alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; type II membrane protein; member of the KRE2/MNT1 mannosyltransferase family" Verified chr15:511826-513007 511826-513007 98.4% 1099.11 1079.35 1060.44 902.32 637.64 461.47 1089.23 981.38 549.56 4.02 3.98 2.28 -0.84 -0.74 Matched[5378]
YOR100C CRC1 "Mitochondrial inner membrane carnitine transporter, required for carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria during fatty acid beta-oxidation" Verified chr15:513296-514279 513296-514279 98.8% 11.32 9.26 9.26 12.35 134.79 50.42 10.29 10.80 92.60 0.04 0.04 0.38 3.10 0.76 Matched[5379]
YOR101W RAS1 "GTPase involved in G-protein signaling in the adenylate cyclase activating pathway, plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes" Verified chr15:515245-516174 515245-516174 98.6% 281.30 232.24 226.79 254.04 64.33 49.06 256.77 240.41 56.70 0.95 0.98 0.23 -2.08 -2.13 Matched[5380]
YOR102W "Dubious open reading frame, unlikely to encode a functional protein; extensively overlaps essential OST2 gene encoding a subunit of the ER lumen oligosaccharyltransferase complex" Dubious chr15:516424-516774 516424-516774 99.2% 562.95 565.82 505.51 562.95 588.80 465.29 564.38 534.23 527.05 2.08 2.17 2.18 -0.02 -0.62 Matched[5381]
YOR103C OST2 "Epsilon subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins" Verified chr15:516450-516842 516450-516842 99.3% 538.06 540.62 471.44 509.88 584.18 425.32 539.34 490.66 504.75 1.99 1.99 2.09 0.04 -0.67 Matched[5381]
YOR104W PIN2 Protein that induces appearance of [PIN+] prion when overproduced Verified chr15:517643-518491 517643-518491 98.7% 146.80 133.67 145.61 112.19 134.86 122.93 140.24 128.90 128.90 0.52 0.52 0.53 0.00 0.10 Matched[5382]
YOR105W "Dubious open reading frame, unlikely to encode a functional protein; based on available experimental and comparative sequence data" Dubious chr15:518196-518522 518196-518522 99.2% 151.08 132.58 157.25 117.16 138.75 132.58 141.83 137.20 135.66 0.52 0.56 0.56 -0.02 0.46 Covered/w/another[5382]
YOR106W VAM3 Syntaxin-related protein required for vacuolar assembly; functions with Vam7p in vacuolar protein trafficking; member of the syntaxin family of proteins Verified chr15:519122-519973 519122-519973 98.5% 108.42 113.19 104.85 86.98 92.94 56.00 110.81 95.91 74.47 0.41 0.39 0.31 -0.37 0.15 Matched[5383]
YOR107W RGS2 Negative regulator of glucose-induced cAMP signaling; directly activates the GTPase activity of the heterotrimeric G protein alpha subunit Gpa2p Verified chr15:521354-522283 521354-522283 98.7% 30.49 71.87 20.69 14.16 7.62 11.98 51.18 17.42 9.80 0.19 0.07 0.04 -0.83 0.51
YOR108W LEU9 "Alpha-isopropylmalate synthase II (2-isopropylmalate synthase), catalyzes the first step in the leucine biosynthesis pathway; the minor isozyme, responsible for the residual alpha-IPMS activity detected in a leu4 null mutant" Verified chr15:523028-524842 523028-524842 89.4% 447.65 426.69 326.18 271.92 38.23 17.88 437.17 299.05 28.06 1.61 1.21 0.12 -3.41 -2.95 Covered/w/another[5384]
YOR108C-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr15:524606-524815 524606-524815 98.8% 626.25 659.98 520.27 375.75 91.53 28.90 643.12 448.01 60.22 2.37 1.82 0.25 -2.90 NaN Covered/w/another[5384]
YOR109W INP53 "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in a TGN (trans Golgi network)-to-early endosome pathway; hyperosmotic stress causes translocation to actin patches" Verified chr15:525279-528602 525279-528602 98.9% 165.83 181.65 171.00 135.70 151.22 159.74 173.74 153.35 155.48 0.64 0.62 0.64 0.02 0.66 Covered/w/another[5384]
YOR110W TFC7 One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes Verified chr15:528942-530249 528942-530249 98.5% 117.25 112.60 145.99 139.00 187.92 111.04 114.93 142.49 149.48 0.42 0.58 0.62 0.07 0.46 Covered/w/another[5384]
YOR111W Putative protein of unknown function Uncharacterized chr15:530430-531128 530430-531128 98.8% 99.93 118.75 104.27 131.79 127.44 84.00 109.34 118.03 105.72 0.40 0.48 0.44 -0.16 0.06 Covered/w/another[5384]
YOR112W CEX1 "Cytoplasmic component of the nuclear aminoacylation-dependent tRNA export pathway; interacts with nuclear pore component Nup116p; copurifies with tRNA export receptors Los1p and Msn5p, as well as eIF-1a and the RAN GTPase Gsp1p" Verified chr15:531509-533794 531509-533794 98.8% 104.44 93.37 113.29 101.34 79.21 80.54 98.91 107.31 79.88 0.37 0.44 0.33 -0.43 0.39 Covered/w/another[5384]
YOR113W AZF1 "Zinc-finger transcription factor, involved in induction of CLN3 transcription in response to glucose; genetic and physical interactions indicate a possible role in mitochondrial transcription or genome maintenance" Verified chr15:534076-536820 534076-536820 98.4% 75.91 82.57 80.72 77.02 99.24 135.15 79.24 78.87 117.20 0.29 0.32 0.49 0.57 1.25 Covered/w/another[5385]
YOR114W Hypothetical protein Uncharacterized chr15:537571-538455 537571-538455 98.8% 61.74 58.31 46.88 41.16 105.18 68.60 60.02 44.02 86.89 0.22 0.18 0.36 0.98 0.61 Covered/w/another[5385]
YOR115C TRS33 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic Verified chr15:538660-539466 538660-539466 99.2% 237.23 247.22 225.99 202.27 252.21 161.07 242.22 214.13 206.64 0.89 0.87 0.86 -0.05 -0.68 Covered/w/another[5385]
YOR116C RPO31 "RNA polymerase III subunit C160, part of core enzyme; similar to bacterial beta-prime subunit" Verified chr15:539764-544146 539764-544146 99.1% 136.06 95.54 92.78 73.44 21.87 24.63 115.80 83.11 23.25 0.43 0.34 0.10 -1.84 -1.20 Covered/w/another[5385]
YOR117W RPT5 One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; recruited to the GAL1-10 promoter region upon induction of transcription Verified chr15:545030-546334 545030-546334 98.5% 499.34 450.34 525.00 495.45 661.11 615.23 474.84 510.22 638.17 1.75 2.07 2.64 0.32 0.71 Matched[5386]
YOR118W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YOR118W is not an essential gene Uncharacterized chr15:546858-548561 546858-548561 98.8% 194.85 184.75 169.90 146.73 182.37 154.45 189.80 158.31 168.41 0.70 0.64 0.70 0.09 0.08 Frag<80[5387]
YOR119C RIO1 Essential serine kinase involved in cell cycle progression and processing of the 20S pre-rRNA into mature 18S rRNA Verified chr15:548793-550247 548793-550247 99.4% 166.01 130.04 121.74 109.29 121.74 110.68 148.03 115.52 116.21 0.55 0.47 0.48 0.01 0.15 Covered[5388]
YOR120W GCY1 "Putative NADP(+) coupled glycerol dehydrogenase, proposed to be involved in an alternative pathway for glycerol catabolism; member of the aldo-keto reductase (AKR) family" Verified chr15:551115-552053 551115-552053 98.8% 106.70 295.31 142.27 156.28 2507.99 1871.03 201.01 149.27 2189.51 0.74 0.61 9.07 3.87 2.49 Matched[5389]
YOR121C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; open reading frame overlaps the verified gene GCY1/YOR120W" Dubious chr15:551799-552104 551799-552104 99.0% 194.67 402.53 237.56 224.36 3513.89 2118.23 298.60 230.96 2816.06 1.10 0.94 11.67 3.61 -0.06 Matched[5389]
YOR122C PFY1 "Profilin, actin- and phosphatidylinositol 4,5-bisphosphate-binding protein, involved in cytoskeleton organization, required for normal timing of actin polymerization in response to thermal stress; localizes to plasma membrane and cytosol" Verified chr15:552299-552888 552299-552666,552876-552888 99.0% 3107.04 3266.10 2971.83 2855.19 3647.85 2428.37 3186.57 2913.51 3038.11 11.76 11.83 12.59 0.06 -0.67 Frag>80[5390,5391,5392]
YOR123C LEO1 "Component of the Paf1 complex, which associates with RNA polymerase II and is involved in histone methylation" Verified chr15:553177-554571 553177-554571 99.4% 404.59 357.71 389.45 363.48 304.35 244.49 381.15 376.46 274.42 1.41 1.53 1.14 -0.46 -0.26 Frag>80[5391,5392,5393]
YOR124C UBP2 "Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins, cleaves at the C terminus of ubiquitin fusions; capable of cleaving polyubiquitin and possesses isopeptidase activity" Verified chr15:554825-558643 554825-558643 99.2% 207.52 236.04 207.00 217.03 299.93 339.27 221.78 212.01 319.60 0.82 0.86 1.32 0.59 0.87 Matched[5394]
YOR125C CAT5 Protein required for ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with ubiquinone biosynthetic enzymes; required for gluconeogenic gene activation Verified chr15:559031-559732 559031-559732 99.0% 263.23 345.22 342.34 306.38 453.10 339.47 304.23 324.36 396.28 1.12 1.32 1.64 0.29 0.07 Frag>80[5395,5396]
YOR126C IAH1 "Isoamyl acetate-hydrolyzing esterase, required in balance with alcohol acetyltransferase to maintain optimal amounts of isoamyl acetate, which is particularly important in sake brewing" Verified chr15:559962-560678 559962-560678 99.0% 123.93 157.73 129.56 121.11 116.89 57.74 140.83 125.34 87.31 0.52 0.51 0.36 -0.52 -0.27 Covered/w/another[5397]
YOR127W RGA1 "GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth" Verified chr15:561171-564194 561171-564194 98.8% 152.28 155.29 132.87 104.08 67.60 61.92 153.78 118.48 64.76 0.57 0.48 0.27 -0.87 -0.28 Covered/w/another[5397]
YOR128C ADE2 "Phosphoribosylaminoimidazole carboxylase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway; red pigment accumulates in mutant cells deprived of adenine" Verified chr15:564477-566192 564477-566192 99.0% 1192.14 864.98 1269.82 1014.44 374.83 258.32 1028.56 1142.13 316.57 3.80 4.64 1.31 -1.85 -1.42 Matched[5398]
YOR129C Putative component of the outer plaque of the spindle pole body; may be involved in cation homeostasis or multidrug resistance Verified chr15:566878-569559 566878-569559 99.0% 41.03 47.06 32.00 28.99 21.08 19.95 44.05 30.49 20.52 0.16 0.12 0.09 -0.57 -0.62 Frag>80[5399,5400]
YOR130C ORT1 "Ornithine transporter of the mitochondrial inner membrane, exports ornithine from mitochondria as part of arginine biosynthesis; human ortholog is associated with hyperammonaemia-hyperornithinaemia-homocitrullinuria (HHH) syndrome" Verified chr15:569930-570808 569930-570808 99.2% 110.06 169.68 100.89 76.81 129.55 74.52 139.87 88.85 102.03 0.52 0.36 0.42 0.20 -0.16 Matched[5401]
YOR131C Putative protein of unknown function; non-essential gene Uncharacterized chr15:572183-572839 572183-572839 99.1% 293.24 268.68 317.81 277.89 420.68 280.96 280.96 297.85 350.82 1.04 1.21 1.45 0.24 0.09 Frag>80[5403,5404]
YOR132W VPS17 Subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde protein transport; peripheral membrane protein that assembles onto the membrane with Vps5p to promote vesicle formation Verified chr15:573176-574831 573176-574831 98.6% 157.38 197.18 162.89 170.23 342.92 255.35 177.28 166.56 299.14 0.65 0.68 1.24 0.84 1.05 Frag>80[5405,5406,5407]
YOR133W EFT1 "Elongation factor 2 (EF-2), also encoded by EFT2; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin" Verified chr15:575099-577627 575099-577627 1.7% 3020.17 1890.49 2466.86 1844.38 899.14 530.26 2455.33 2155.62 714.70 9.06 8.75 2.96 -1.59 -1.74 Frag<80[5406,5407,5408,5409,5410]
YOR134W BAG7 "Rho GTPase activating protein (RhoGAP), stimulates the intrinsic GTPase activity of Rho1p, which plays a role in actin cytoskeleton organization and control of cell wall synthesis; structurally and functionally related to Sac7p" Verified chr15:578565-579794 578565-579794 98.8% 13.16 20.56 8.23 13.98 115.98 54.29 16.86 11.10 85.14 0.06 0.05 0.35 2.94 2.59 Matched[5411]
YOR136W IDH2 "Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle; phosphorylated" Verified chr15:580251-581360 580251-581360 99.1% 1174.95 2135.27 1207.68 1459.59 3071.05 2370.81 1655.11 1333.64 2720.93 6.11 5.41 11.27 1.03 0.85 Matched[5412]
YOR135C Hypothetical protein; null mutant displays increased levels of spontaneous Rad52 foci Dubious chr15:580160-580501 580160-580501 98.9% 928.54 1570.23 810.25 1111.88 1960.57 1904.39 1249.38 961.06 1932.48 4.61 3.90 8.01 1.01 0.09 Covered/w/another[5412]
YOR137C SIA1 Protein of unassigned function involved in activation of the Pma1p plasma membrane H+-ATPase by glucose Verified chr15:581814-583682 581814-583682 99.2% 73.89 103.02 84.68 107.33 216.28 158.57 88.46 96.01 187.43 0.33 0.39 0.78 0.97 1.16 Matched[5413]
YOR138C RUP1 "Protein involved in regulation of Rsp5p, which is an essential HECT ubiquitin ligase; required for binding of Rsp5p to Ubp2p; contains an UBA domain" Verified chr15:584310-586325 584310-586325 98.9% 109.80 133.87 126.85 93.26 138.88 90.75 121.84 110.05 114.82 0.45 0.45 0.48 0.06 0.39 Matched[5414]
YOR140W SFL1 "Transcriptional repressor and activator; involved in repression of flocculation-related genes, and activation of stress responsive genes; negatively regulated by cAMP-dependent protein kinase A subunit Tpk2p" Verified chr15:586982-589282 586982-589282 98.8% 123.19 104.27 112.63 101.19 49.27 58.07 113.73 106.91 53.67 0.42 0.43 0.22 -0.99 0.18 Covered/w/another[5415]
YOR139C Hypothetical protein Dubious chr15:586951-587343 586951-587343 98.1% 67.41 72.59 70.00 59.63 33.70 28.52 70.00 64.82 31.11 0.26 0.26 0.13 -1.06 0.72 Covered/w/another[5415]
YOR141C ARP8 "Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes" Verified chr15:589943-592588 589943-592588 99.2% 97.16 102.50 89.16 99.07 87.64 104.79 99.83 94.12 96.21 0.37 0.38 0.40 0.03 0.56 Covered/w/another[5415]
YOR142W LSC1 "Alpha subunit of succinyl-CoA ligase, which is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate; phosphorylated" Verified chr15:593058-594047 593058-594047 98.7% 719.52 770.69 788.09 792.19 664.25 331.61 745.11 790.14 497.93 2.75 3.21 2.06 -0.67 -0.74 Matched[5416]
YOR143C THI80 "Thiamine pyrophosphokinase, phosphorylates thiamine to produce the coenzyme thiamine pyrophosphate (thiamine diphosphate)" Verified chr15:601384-602343 601384-602343 99.4% 127.90 104.84 115.32 89.11 74.44 35.65 116.37 102.22 55.04 0.43 0.41 0.23 -0.89 -1.20 Matched[5418]
YOR144C ELG1 "Protein required for S phase progression and telomere homeostasis, forms an alternative replication factor C complex important for DNA replication and genome integrity; involved in homologous recombination-mediated DNA repair" Verified chr15:602718-605093 602718-605093 99.1% 52.21 53.49 34.81 29.29 31.41 19.95 52.85 32.05 25.68 0.20 0.13 0.11 -0.32 -0.23 Matched[5419]
YOR146W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; open reading frame overlaps the verified gene PNO1/YOR145C" Dubious chr15:605874-606179 605874-606179 99.3% 368.77 184.39 204.14 158.05 32.93 9.88 276.58 181.09 21.40 1.02 0.74 0.09 -3.08 -0.14 Matched[5420]
YOR145C PNO1 "Essential nucleolar protein required for pre-18S rRNA processing, interacts with Dim1p, an 18S rRNA dimethyltransferase, and also with Nob1p, which is involved in proteasome biogenesis; contains a KH domain" Verified chr15:605348-606172 605348-606172 99.1% 413.52 241.02 254.47 173.73 44.04 22.02 327.27 214.10 33.03 1.21 0.87 0.14 -2.70 -3.09 Matched[5420]
YOR147W MDM32 "Mitochondrial inner membrane protein with similarity to Mdm31p, required for normal mitochondrial morphology and inheritance; interacts genetically with MMM1, MDM10, MDM12, and MDM34" Verified chr15:606608-608476 606608-608476 99.1% 137.73 143.13 131.79 137.19 156.09 158.79 140.43 134.49 157.44 0.52 0.55 0.65 0.23 0.43 Frag<80[5421]
YOR148C SPP2 "Essential protein that promotes the first step of splicing and is required for the final stages of spliceosome maturation; interacts with Prp2p, which may release Spp2p from the spliceosome following the first cleavage reaction" Verified chr15:608641-609198 608641-609198 99.4% 315.50 254.21 239.78 171.27 257.81 138.82 284.86 205.53 198.32 1.05 0.83 0.82 -0.05 -0.73 Matched[5422]
YOR149C SMP3 "Alpha 1,2-mannosyltransferase involved in glycosyl phosphatidyl inositol (GPI) biosynthesis; required for addition of the fourth, side branching mannose to the GPI core structure" Verified chr15:609839-611389 609839-611389 98.8% 104.36 126.54 90.01 69.14 67.84 45.01 115.45 79.58 56.42 0.43 0.32 0.23 -0.50 -0.48 Matched[5423]
YOR150W MRPL23 Mitochondrial ribosomal protein of the large subunit Verified chr15:612000-612491 612000-612491 98.8% 397.22 388.99 362.23 380.76 520.71 349.88 393.11 371.49 435.30 1.45 1.51 1.80 0.23 0.37 Matched[5424]
YOR151C RPB2 "RNA polymerase II second largest subunit B150, part of central core; similar to bacterial beta subunit" Verified chr15:612998-616672 612998-616672 99.2% 478.85 406.40 413.54 381.71 265.36 249.71 442.63 397.62 257.53 1.63 1.61 1.07 -0.63 -0.56 Frag>80[5425,5426,5427]
YOR152C Putative protein of unknown function; has no similarity to any known protein; YOR152C is not an essential gene Uncharacterized chr15:617519-618289 617519-618289 98.7% 120.88 119.57 101.17 39.42 248.33 118.25 120.22 70.29 183.29 0.44 0.29 0.76 1.38 1.69 Matched[5428]
YOR153W PDR5 "Plasma membrane ATP-binding cassette (ABC) transporter, short-lived multidrug transporter actively regulated by Pdr1p; also involved in steroid transport, cation resistance, and cellular detoxification during exponential growth" Verified chr15:619841-624376 619841-624376 98.4% 1079.49 743.56 880.27 595.66 465.46 539.63 911.53 737.96 502.54 3.36 3.00 2.08 -0.55 0.28 Frag>80[5430,5431,5432]
YOR154W SLP1 Integral membrane protein of unknown function; member of the SUN-like family of proteins Uncharacterized chr15:624730-626493 624730-626493 98.6% 64.37 59.77 51.73 40.23 21.84 21.84 62.07 45.98 21.84 0.23 0.19 0.09 -1.07 -0.75 Matched[5433]
YOR155C ISN1 "Inosine 5'-monophosphate (IMP)-specific 5'-nucleotidase, catalyzes the breakdown of IMP to inosine, does not show similarity to known 5'-nucleotidases from other organisms" Verified chr15:626629-627981 626629-627981 99.0% 221.63 291.03 244.01 225.36 368.63 270.13 256.33 234.69 319.38 0.95 0.95 1.32 0.44 0.51 Matched[5434]
YOR156C NFI1 "SUMO ligase, catalyzes the covalent attachment of SUMO (Smt3p) to proteins; involved in maintenance of proper telomere length" Verified chr15:628361-630541 628361-630541 98.5% 49.83 60.07 54.95 50.76 46.10 36.32 54.95 52.86 41.21 0.20 0.21 0.17 -0.36 0.49 Matched[5435]
YOR157C PUP1 Endopeptidase with trypsin-like activity that cleaves after basic residues; beta-type subunit of 20S proteasome synthesized as a proprotein before being proteolytically processed for assembly into 20S particle; human homolog is subunit Z Verified chr15:630967-631752 630967-631752 99.0% 673.27 570.48 702.82 614.17 1042.03 758.07 621.87 658.49 900.05 2.30 2.67 3.73 0.45 0.58 Frag>80[5436,5437]
YOR158W PET123 "Mitochondrial ribosomal protein of the small subunit; PET123 exhibits genetic interactions with PET122, which encodes a COX3 mRNA-specific translational activator" Verified chr15:632165-633121 632165-633121 98.9% 323.45 366.79 381.59 365.73 554.94 358.34 345.12 373.66 456.64 1.27 1.52 1.89 0.29 0.24 Matched[5438]
YOR159C SME1 "Core Sm protein Sm E; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm E" Verified chr15:633283-633567 633283-633567 99.5% 285.76 229.31 254.01 208.14 229.31 257.53 257.53 231.07 243.42 0.95 0.94 1.01 0.08 -0.27 Matched[5439]
YOR160W MTR10 "Nuclear import receptor, mediates the nuclear localization of proteins involved in mRNA-nucleus export; promotes dissociation of mRNAs from the nucleus-cytoplasm mRNA shuttling protein Npl3p" Verified chr15:633840-636758 633840-636758 99.1% 102.71 118.28 81.62 98.91 111.02 125.89 110.50 90.26 118.45 0.41 0.37 0.49 0.39 0.84 Matched[5440]
YOR161W-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr15:637575-637655 637575-637655 99.2% 111.98 111.98 149.30 111.98 1393.47 1231.73 111.98 130.64 1312.60 0.41 0.53 5.44 3.33 NaN Covered/w/another[5441]
YOR161W-B "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr15:637976-638236 637976-638236 98.5% 70.00 58.34 116.67 120.56 933.40 859.50 64.17 118.62 896.45 0.24 0.48 3.71 2.92 NaN Covered/w/another[5441]
YOR161C PNS1 "Protein of unknown function; has similarity to Torpedo californica tCTL1p, which is postulated to be a choline transporter, neither null mutation nor overexpression affects choline transport" Verified chr15:636940-638559 636940-638559 98.5% 98.97 109.62 157.85 148.46 1457.64 1081.17 104.30 153.16 1269.41 0.39 0.62 5.26 3.05 3.21 Matched[5441]
YOR161C-C "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr15:639122-639268 639122-639268 98.4% 27.66 20.74 6.91 0.00 13.83 13.83 24.20 3.46 13.83 0.09 0.01 0.06 2.00 NaN Matched[5442]
YOR162C YRR1 "Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrm1p, acting on an overlapping set of target genes" Verified chr15:639561-641993 639561-641993 99.1% 63.88 66.78 58.48 55.58 108.67 93.74 65.33 57.03 101.20 0.24 0.23 0.42 0.83 1.40 Matched[5443]
YOR163W DDP1 "Diadenosine polyphosphate hydrolase, member of the MutT family of nucleotide hydrolases with high specificity for diadenosine hexa- and pentaphosphates, required for efficient hydrolysis of diphosphorylated inositol polyphosphates" Verified chr15:642742-643308 642742-643308 98.3% 518.35 559.60 559.60 577.54 760.48 523.73 538.97 568.57 642.10 1.99 2.31 2.66 0.18 0.42 Matched[5444]
YOR164C Protein of unknown function; interacts with Mdy2p Verified chr15:643395-644333 643395-644333 99.5% 476.42 449.66 437.88 396.13 463.58 351.16 463.04 417.00 407.37 1.71 1.69 1.69 -0.03 0.24 Matched[5445]
YOR165W SEY1 "Protein of unknown function, contains two predicted GTP-binding motifs GXXXXGKS and DXXG near the N-terminus, homolog of the Arabidopsis gene RHD3 (Root Hair Defective)" Verified chr15:644567-646897 644567-646897 98.7% 308.04 289.36 292.40 287.62 169.44 126.00 298.70 290.01 147.72 1.10 1.18 0.61 -0.97 -0.74 Matched[5446]
YOR166C SWT1 Protein of unknown function; involved in transcription associated process; interacts genetically and physically with the TREX complex and RNA polymerase II; contains a PINc domain (PilT N terminus); localizes in the nucleus Verified chr15:647127-648503 647127-648503 99.2% 100.99 97.33 87.09 79.04 49.03 33.66 99.16 83.06 41.35 0.37 0.34 0.17 -1.01 -1.03 Matched[5447]
YOR167C RPS28A Protein component of the small (40S) ribosomal subunit; nearly identical to Rps28Bp and has similarity to rat S28 ribosomal protein Verified chr15:648805-649008 648805-649008 94.3% 10300.56 9152.01 9604.16 9094.85 4131.66 4168.04 9726.29 9349.50 4149.85 35.90 37.95 17.19 -1.17 -2.49 Matched[5448]
YOR168W GLN4 "Glutamine tRNA synthetase, monomeric class I tRNA synthetase that catalyzes the specific glutaminylation of tRNA(Glu); N-terminal domain proposed to be involved in enzyme-tRNA interactions" Verified chr15:649304-651733 649304-651733 98.8% 636.25 450.42 532.92 482.08 220.42 217.08 543.33 507.50 218.75 2.01 2.06 0.91 -1.21 -0.80 Matched[5449]
YOR169C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; open reading frame overlaps the verified gene GLN4/YOR168W" Dubious chr15:651377-651841 651377-651841 99.0% 956.18 656.28 671.50 691.05 352.05 282.51 806.23 681.27 317.28 2.98 2.77 1.31 -1.10 0.00 Covered/w/another[5449]
YOR170W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene LCB4" Dubious chr15:651859-652164 651859-652164 99.6% 242.82 246.10 262.51 193.60 239.54 196.88 244.46 228.06 218.21 0.90 0.93 0.90 -0.06 0.04 Covered/w/another[5450]
YOR171C LCB4 "Sphingoid long-chain base kinase, responsible for synthesis of long-chain base phosphates, which function as signaling molecules, regulates synthesis of ceramide from exogenous long-chain bases, localizes to the Golgi and late endosomes" Verified chr15:652011-653885 652011-653885 99.2% 184.50 169.44 167.82 177.51 159.76 169.98 176.97 172.67 164.87 0.65 0.70 0.68 -0.07 0.38 Matched[5450]
YOR172W YRM1 "Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrr1p, acting on an overlapping set of target genes" Verified chr15:654211-656571 654211-656571 98.8% 97.34 101.20 95.62 78.90 106.34 77.18 99.27 87.26 91.76 0.37 0.35 0.38 0.07 0.77 Matched[5451]
YOR173W DCS2 "Non-essential, stress induced regulatory protein containing a HIT (histidine triad) motif; modulates m7G-oligoribonucleotide metabolism; inhibits Dcs1p; regulated by Msn2p, Msn4p, and the Ras-cAMP-cAPK signaling pathway, similar to Dcs1p." Verified chr15:657265-658326 657265-658326 98.5% 105.15 359.44 224.65 227.52 2812.40 1791.44 232.30 226.08 2301.92 0.86 0.92 9.54 3.35 3.15 Matched[5453]
YOR174W MED4 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation Verified chr15:658748-659602 658748-659602 98.5% 157.88 146.01 148.38 156.69 138.89 65.29 151.94 152.54 102.09 0.56 0.62 0.42 -0.58 -1.07 Matched[5454]
YOR175C ALE1 "Lysophospholipid acyltransferase, partially redundant with Slc1p; member of MBOAT family of membrane-bound O-acyltransferases; may be involved in fatty acid exchange at the sn-2 position of mature glycerophospholipids" Verified chr15:659816-661675 659816-661675 99.1% 330.51 541.08 321.82 334.31 257.24 161.18 435.79 328.06 209.21 1.61 1.33 0.87 -0.65 -0.55 Matched[5455]
YOR176W HEM15 "Ferrochelatase, a mitochondrial inner membrane protein, catalyzes the insertion of ferrous iron into protoporphyrin IX, the eighth and final step in the heme biosynthetic pathway" Verified chr15:662402-663583 662402-663583 98.8% 470.00 751.66 509.38 568.45 737.10 574.45 610.83 538.92 655.78 2.25 2.19 2.72 0.28 0.27 Matched[5456]
YOR177C MPC54 "Component of the meiotic outer plaque, a membrane-organizing center which is assembled on the cytoplasmic face of the spindle pole body during meiosis II and triggers the formation of the prospore membrane; potential Cdc28p substrate" Verified chr15:665786-667180 665786-667180 99.3% 10.82 16.60 14.43 13.71 44.74 36.80 13.71 14.07 40.77 0.05 0.06 0.17 1.53 1.58 Frag>80[5458]
YOR178C GAC1 "Regulatory subunit for Glc7p type-1 protein phosphatase (PP1), tethers Glc7p to Gsy2p glycogen synthase, binds Hsf1p heat shock transcription factor, required for induction of some HSF-regulated genes under heat shock" Verified chr15:667861-670242 667861-670242 98.8% 66.31 108.39 104.14 110.09 267.37 426.34 87.35 107.12 346.85 0.32 0.43 1.44 1.70 1.94 Covered[5459]
YOR179C SYC1 "Subunit of the APT subcomplex of cleavage and polyadenylation factor, may have a role in 3' end formation of both polyadenylated and non-polyadenylated RNAs" Verified chr15:671846-672412 671846-672412 99.4% 122.43 124.21 110.01 62.10 170.34 90.49 123.32 86.06 130.42 0.46 0.35 0.54 0.60 0.10 Matched[5461]
YOR180C DCI1 "Peroxisomal delta(3,5)-delta(2,4)-dienoyl-CoA isomerase, involved in fatty acid metabolism, contains peroxisome targeting signals at amino and carboxy termini" Verified chr15:674353-675168 674353-675168 99.2% 74.10 87.69 59.28 50.64 58.05 35.82 80.90 54.96 46.93 0.30 0.22 0.19 -0.23 -0.42 Covered/w/another[5462]
YOR181W LAS17 "Actin assembly factor, activates the Arp2/3 protein complex that nucleates branched actin filaments; localizes with the Arp2/3 complex to actin patches; homolog of the human Wiskott-Aldrich syndrome protein (WASP)" Verified chr15:675940-677841 675940-677841 98.8% 171.91 171.38 179.89 172.97 201.71 221.40 171.64 176.43 211.56 0.63 0.72 0.88 0.26 0.82 Covered/w/another[5462]
YOR182C RPS30B Protein component of the small (40S) ribosomal subunit; nearly identical to Rps30Ap and has similarity to rat S30 ribosomal protein Verified chr15:678192-678794 678192-678380,678792-678794 55.5% 9845.91 7189.68 7837.31 6251.08 2797.03 2243.25 8517.79 7044.19 2520.14 31.44 28.59 10.44 -1.48 -2.38 Matched[5463]
YOR183W FYV12 "Protein of unknown function, required for survival upon exposure to K1 killer toxin" Uncharacterized chr15:678873-679262 678873-679262 98.6% 23.41 5.20 2.60 7.80 13.01 10.40 14.31 5.20 11.70 0.05 0.02 0.05 1.17 -0.38 Overlap[5464]
YOR184W SER1 "3-phosphoserine aminotransferase, catalyzes the formation of phosphoserine from 3-phosphohydroxypyruvate, required for serine and glycine biosynthesis; regulated by the general control of amino acid biosynthesis mediated by Gcn4p" Verified chr15:679358-680545 679358-680545 98.7% 1425.66 1180.94 1326.75 1120.40 382.85 248.13 1303.30 1223.58 315.49 4.81 4.97 1.31 -1.96 -1.48 Matched[5464]
YOR185C GSP2 "GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RNA processing and transport; interacts with Kap121p, Kap123p and Pdr6p (karyophilin betas); Gsp1p homolog that is not required for viability" Verified chr15:681445-682107 681445-682107 95.6% 411.62 826.39 548.82 462.08 2062.82 1367.33 619.00 505.45 1715.07 2.29 2.05 7.11 1.76 0.87 Matched[5467]
YOR186W Putative protein of unknown function; proper regulation of expression during heat stress is sphingolipid-dependent Uncharacterized chr15:683112-683546 683112-683546 98.6% 9.33 11.66 11.66 7.00 93.27 55.96 10.49 9.33 74.61 0.04 0.04 0.31 3.00 4.01 Matched[5468]
YOR186C-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr15:683330-683539 683330-683539 98.7% 9.65 14.48 19.30 9.65 96.50 57.90 12.06 14.48 77.20 0.04 0.06 0.32 2.42 NaN Covered/w/another[5468]
YOR187W TUF1 "Mitochondrial translation elongation factor Tu; comprises both GTPase and guanine nucleotide exchange factor activities, while these activities are found in separate proteins in S. pombe and humans" Verified chr15:684031-685344 684031-685344 98.6% 1106.94 1051.37 1248.21 1289.89 1502.94 1124.70 1079.15 1269.05 1313.82 3.98 5.15 5.44 0.05 0.22 Matched[5469]
YOR188W MSB1 "Protein involved in positive regulation of both 1,3-beta-glucan synthesis and the Pkc1p-MAPK pathway, potential Cdc28p substrate; multicopy suppressor of temperature-sensitive mutations in CDC24 and CDC42, and of mutations in BEM4" Verified chr15:685768-689181 685768-689181 98.8% 120.95 102.57 90.12 78.26 32.31 32.61 111.76 84.19 32.46 0.41 0.34 0.13 -1.37 -0.50 Matched[5470]
YOR189W IES4 Component of the INO80 chromatiin remodeling complex and target of the Mec1p/Tel1p DNA damage signaling pathway; proposed to link chromatin remodeling to replication checkpoint responses Verified chr15:689625-689975 689625-689975 98.3% 298.66 287.06 263.86 321.86 426.24 269.66 292.86 292.86 347.95 1.08 1.19 1.44 0.25 0.14 Matched[5471]
YOR190W SPR1 "Sporulation-specific exo-1,3-beta-glucanase; contributes to ascospore thermoresistance" Verified chr15:690696-692033 690696-692033 98.7% 34.83 40.13 23.47 15.14 23.47 15.14 37.48 19.31 19.31 0.14 0.08 0.08 0.00 0.22
YOR191W RIS1 "Member of the SWI/SNF family of DNA-dependent ATPases, plays a role in antagonizing silencing during mating-type switching, contains an N-terminal domain that interacts with Sir4p and a C-terminal SNF2 domain" Verified chr15:692476-697335 692476-697335 98.7% 96.98 119.51 85.30 97.61 55.27 90.10 108.25 91.46 72.69 0.40 0.37 0.30 -0.33 0.34 Matched[5473]
YOR192C THI72 Transporter of thiamine or related compound; shares sequence similarity with Thi7p Verified chr15:698769-700568 698769-700568 82.6% 19.50 32.27 14.79 9.41 8.74 12.10 25.88 12.10 10.42 0.10 0.05 0.04 -0.22 0.41 Overlap[5474]
YOR192C-C Putative protein of unknown function; identified by expression profiling and mass spectrometry Uncharacterized chr15:703989-704225 703989-704225 10.4% 122.24 122.24 122.24 122.24 0.00 81.49 122.24 122.24 40.75 0.45 0.50 0.17 -1.58 NaN Frag<80[5476]
YOR193W PEX27 "Peripheral peroxisomal membrane protein involved in controlling peroxisome size and number, interacts with homologous protein Pex25p" Verified chr15:710447-711577 710447-711577 98.9% 76.85 82.21 68.81 64.34 127.79 79.53 79.53 66.57 103.66 0.29 0.27 0.43 0.64 0.46 Matched[5477]
YOR194C TOA1 "TFIIA large subunit; involved in transcriptional activation, acts as antirepressor or as coactivator; homologous to largest and second largest subunits of human and Drosophila TFIIA" Verified chr15:711684-712544 711684-712544 99.5% 394.65 375.97 375.97 340.94 465.87 360.79 385.31 358.45 413.33 1.42 1.46 1.71 0.21 0.35 Matched[5478]
YOR195W SLK19 "Kinetochore-associated protein required for normal segregation of chromosomes in meiosis and mitosis; component of the FEAR regulatory network, which promotes Cdc14p release from the nucleolus during anaphase; potential Cdc28p substrate" Verified chr15:712867-715332 712867-715332 98.7% 146.62 128.55 128.55 121.98 98.16 58.32 137.59 125.27 78.24 0.51 0.51 0.32 -0.68 -0.54 Covered/w/another[5479]
YOR196C LIP5 "Protein involved in biosynthesis of the coenzyme lipoic acid, has similarity to E. coli lipoic acid synthase" Verified chr15:715594-716838 715594-716838 99.3% 197.32 167.40 152.04 153.65 110.79 90.58 182.36 152.85 100.68 0.67 0.62 0.42 -0.60 -0.50 Covered/w/another[5479]
YOR197W MCA1 "Putative cysteine protease similar to mammalian caspases, involved in regulation of apoptosis upon hydrogen peroxide treatment" Verified chr15:717087-718385 717087-718385 98.7% 461.12 381.53 396.36 355.79 329.26 267.62 421.33 376.07 298.44 1.56 1.53 1.24 -0.33 -0.19 Matched[5480]
YOR198C BFR1 Component of mRNP complexes associated with polyribosomes; implicated in secretion and nuclear segregation; multicopy suppressor of BFA (Brefeldin A) sensitivity Verified chr15:718654-720066 718654-720066 99.2% 1517.04 1113.87 1325.80 1335.08 954.75 869.83 1315.45 1330.44 912.29 4.86 5.40 3.78 -0.54 -0.39 Matched[5481]
YOR199W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr15:720182-720511 720182-720511 99.3% 112.91 155.63 122.06 85.44 73.24 106.80 134.27 103.75 90.02 0.50 0.42 0.37 -0.20 -0.23 Covered/w/another[5481]
YOR200W Hypothetical protein Dubious chr15:720418-720816 720418-720816 99.1% 225.03 303.41 242.73 169.41 103.67 101.14 264.22 206.07 102.40 0.98 0.84 0.42 -1.01 -0.44
YOR201C MRM1 "Ribose methyltransferase that modifies a functionally critical, conserved nucleotide in mitochondrial 21S rRNA" Verified chr15:720471-721709 720471-721709 99.0% 211.26 239.80 212.07 172.92 83.20 77.49 225.53 192.50 80.34 0.83 0.78 0.33 -1.26 -0.87 Frag>80[5482]
YOR202W HIS3 "Imidazoleglycerol-phosphate dehydratase, catalyzes the sixth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control via Gcn4p" Verified chr15:721947-722609 721947-722609 98.4% 340.21 580.81 352.47 266.65 139.45 110.34 460.51 309.56 124.90 1.70 1.26 0.52 -1.31 0.04 Covered/w/another[5483]
YOR203W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps 5' end of essential DED1 gene required for translation initiation" Dubious chr15:722566-722919 722566-722919 98.6% 246.45 343.88 212.06 180.54 83.10 94.57 295.16 196.30 88.84 1.09 0.80 0.37 -1.14 -1.27 Covered/w/another[5483]
YOR204W DED1 "ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase, required for translation initiation of all yeast mRNAs; mutations in human DEAD-box DBY are a frequent cause of male infertility" Verified chr15:722912-724726 722912-724726 98.5% 574.93 560.95 453.57 373.03 234.89 303.68 567.94 413.30 269.29 2.10 1.68 1.12 -0.62 0.19 Covered/w/another[5483]
YOR205C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr15:725565-727235 725565-727235 99.2% 112.85 127.34 79.66 67.59 44.66 58.54 120.09 73.63 51.60 0.44 0.30 0.21 -0.51 -0.52 Matched[5484]
YOR206W NOC2 "Protein that forms a nucleolar complex with Mak21p that binds to 90S and 66S pre-ribosomes, as well as a nuclear complex with Noc3p that binds to 66S pre-ribosomes; both complexes mediate intranuclear transport of ribosomal precursors" Verified chr15:727513-729645 727513-729645 98.7% 402.17 183.75 236.93 197.05 23.27 5.22 292.96 216.99 14.24 1.08 0.88 0.06 -3.93 -4.93 Covered/w/another[5485]
YOR207C RET1 "Second-largest subunit of RNA polymerase III, which is responsible for the transcription of tRNA and 5S RNA genes, and other low molecular weight RNAs" Verified chr15:730009-733458 730009-733458 99.2% 191.19 112.26 124.83 116.93 22.80 27.48 151.72 120.88 25.14 0.56 0.49 0.10 -2.27 -1.50 Covered/w/another[5485]
YOR208W PTP2 Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the nucleus Verified chr15:733926-736178 733926-736178 99.2% 84.13 116.79 101.13 91.29 197.79 182.57 100.46 96.21 190.18 0.37 0.39 0.79 0.98 1.31 Matched[5486]
YOR209C NPT1 "Nicotinate phosphoribosyltransferase, acts in the salvage pathway of NAD+ biosynthesis; required for silencing at rDNA and telomeres and has a role in silencing at mating-type loci; localized to the nucleus" Verified chr15:736438-737727 736438-737727 99.2% 662.72 584.57 572.84 560.34 283.69 264.93 623.64 566.59 274.31 2.30 2.30 1.14 -1.05 -0.40 Matched[5487]
YOR210W RPB10 "RNA polymerase subunit ABC10-beta, common to RNA polymerases I, II, and III" Verified chr15:738321-738533 738321-738533 98.8% 1088.32 1021.78 950.50 831.68 489.50 465.74 1055.05 891.09 477.62 3.89 3.62 1.98 -0.90 -0.78 Matched[5488]
YOR211C MGM1 "Mitochondrial GTPase related to dynamin, present in a complex containing Ugo1p and Fzo1p; required for normal morphology of cristae and for stability of Tim11p; homolog of human OPA1 involved in autosomal dominant optic atrophy" Verified chr15:738925-741570 738925-741570 99.2% 125.73 140.58 130.68 124.20 111.63 89.53 133.16 127.44 100.58 0.49 0.52 0.42 -0.34 -0.00 Matched[5489]
YOR212W STE4 "G protein beta subunit, forms a dimer with Ste18p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste18p to dampen signaling; may recruit Rho1p to the polarized growth site during mating; contains WD40 repeats" Verified chr15:742911-744182 742911-744182 98.7% 472.90 448.22 476.88 456.98 244.41 103.50 460.56 466.93 173.95 1.70 1.90 0.72 -1.42 -1.50 Matched[5490]
YOR213C SAS5 "Subunit of the SAS complex (Sas2p, Sas4p, Sas5p), which acetylates free histones and nucleosomes and regulates transcriptional silencing; stimulates Sas2p HAT activity" Verified chr15:744536-745282 744536-745282 99.1% 174.22 143.15 101.29 78.33 59.42 28.36 158.69 89.81 43.89 0.59 0.36 0.18 -1.03 -1.33 Matched[5491]
YOR214C Putative protein of unknown function; YOR214C is not an essential gene Uncharacterized chr15:745594-746304 745594-746304 98.9% 2.84 4.26 2.84 2.84 1.42 7.11 3.55 2.84 4.26 0.01 0.01 0.02 0.58 -0.73 Frag<80[5492]
YOR215C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr15:746726-747283 746726-747283 99.2% 625.21 724.59 856.50 740.85 1534.11 981.18 674.90 798.67 1257.64 2.49 3.24 5.21 0.66 0.16 Matched[5493]
YOR216C RUD3 Golgi matrix protein involved in the structural organization of the cis-Golgi; interacts genetically with COG3 and USO1 Verified chr15:747526-748980 747526-748980 99.4% 188.12 168.06 181.89 168.75 189.50 146.62 178.09 175.32 168.06 0.66 0.71 0.70 -0.06 0.42 Matched[5494]
YOR217W RFC1 "Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon" Verified chr15:749302-751887 749302-751887 98.6% 224.65 182.70 203.48 184.27 115.27 106.25 203.68 193.88 110.76 0.75 0.79 0.46 -0.81 -0.05 Matched[5495]
YOR218C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; open reading frame overlaps the verified gene RFC1/YOR217W" Dubious chr15:751477-751896 751477-751896 98.4% 411.17 338.61 365.21 331.35 217.68 174.14 374.89 348.28 195.91 1.38 1.41 0.81 -0.83 -0.07 Covered/w/another[5495]
YOR219C STE13 "Dipeptidyl aminopeptidase, Golgi integral membrane protein that cleaves on the carboxyl side of repeating -X-Ala- sequences, required for maturation of alpha factor, transcription is induced by a-factor" Verified chr15:752215-755010 752215-755010 99.1% 127.04 143.28 124.88 119.46 142.20 157.00 135.16 122.17 149.60 0.50 0.50 0.62 0.29 0.71 Matched[5496]
YOR220W Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS Uncharacterized chr15:755329-756126 755329-756126 99.0% 148.07 259.44 227.80 234.13 977.01 873.23 203.75 230.96 925.12 0.75 0.94 3.83 2.00 2.13 Matched[5497]
YOR221C MCT1 "Predicted malonyl-CoA:ACP transferase, putative component of a type-II mitochondrial fatty acid synthase that produces intermediates for phospholipid remodeling" Verified chr15:756477-757559 756477-757559 98.9% 161.52 263.30 177.40 182.07 262.36 222.21 212.41 179.73 242.29 0.78 0.73 1.00 0.43 0.65 Matched[5498]
YOR222W ODC2 "Mitochondrial inner membrane transporter, exports 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol for use in lysine and glutamate biosynthesis and in lysine catabolism" Verified chr15:758331-759254 758331-759254 98.5% 286.76 248.31 224.13 181.29 88.99 29.66 267.53 202.71 59.33 0.99 0.82 0.25 -1.77 -1.55 Frag>80[5499,5500,5501]
YOR223W Putative protein of unknown function Uncharacterized chr15:759783-760661 759783-760661 98.2% 118.17 140.18 118.17 111.22 220.12 149.45 129.18 114.69 184.78 0.48 0.47 0.77 0.69 0.52 Matched[5502]
YOR224C RPB8 "RNA polymerase subunit ABC14.5, common to RNA polymerases I, II, and III" Verified chr15:760826-761266 760826-761266 98.5% 1003.93 757.56 923.34 794.40 363.81 324.67 880.74 858.87 344.24 3.25 3.49 1.43 -1.32 -1.03 Matched[5503]
YOR225W "Dubious open reading frame, unlikely to encode a functional protein; based on available experimental and comparative sequence data" Dubious chr15:761393-761722 761393-761722 99.1% 330.23 314.94 330.23 284.37 235.44 113.14 322.59 307.30 174.29 1.19 1.25 0.72 -0.82 0.01 Matched[5504]
YOR226C ISU2 "Conserved protein of the mitochondrial matrix, required for synthesis of mitochondrial and cytosolic iron-sulfur proteins, performs a scaffolding function in mitochondria during Fe/S cluster assembly; isu1 isu2 double mutant is inviable" Verified chr15:761615-762085 761615-762085 98.6% 406.96 314.37 437.11 402.66 279.92 193.79 360.67 419.88 236.86 1.33 1.70 0.98 -0.83 -0.62 Matched[5505]
YOR227W "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr15:762826-766566 762826-766566 98.9% 166.72 257.25 208.88 187.26 214.28 251.03 211.99 198.07 232.66 0.78 0.80 0.96 0.23 0.69 Matched[5506]
YOR228C "Protein of unknown function, localized to the mitochondrial outer membrane" Verified chr15:766870-767778 766870-767778 98.7% 59.10 98.13 98.13 94.78 238.63 217.44 78.61 96.45 228.04 0.29 0.39 0.94 1.24 1.40 Covered/w/another[5507]
YOR229W WTM2 Transcriptional repressor involved in regulation of meiosis and silencing; contains WD repeats Verified chr15:768410-769813 768410-769813 97.9% 120.08 182.66 97.52 82.96 53.12 41.48 151.37 90.24 47.30 0.56 0.37 0.20 -0.93 -1.18 Covered/w/another[5507]
YOR230W WTM1 "Transcriptional repressor involved in regulation of meiosis and silencing, required for nuclear localization of the ribonucleotide reductase small subunit Rnr2p and Rnr4p; contains WD repeats" Verified chr15:770801-772114 770801-772114 98.8% 1686.06 3115.63 1964.89 1868.61 2889.18 2957.73 2400.85 1916.75 2923.46 8.86 7.78 12.11 0.61 1.03 Matched[5508]
YOR231W MKK1 "Mitogen-activated kinase kinase involved in protein kinase C signaling pathway that controls cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p" Verified chr15:772602-774128 772602-774128 98.8% 139.23 142.55 135.25 101.44 105.42 78.23 140.89 118.35 91.83 0.52 0.48 0.38 -0.37 -0.02 Matched[5509]
YOR231C-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr15:773164-773364 773164-773364 98.4% 111.23 131.45 146.62 101.12 65.73 45.50 121.34 123.87 55.61 0.45 0.50 0.23 -1.16 NaN Covered/w/another[5509]
YOR232W MGE1 Protein of the mitochondrial matrix involved in protein import into mitochondria; acts as a cochaperone and a nucleotide release factor for Ssc1p; homolog of E. coli GrpE Verified chr15:774574-775260 774574-775260 98.5% 1285.40 1032.75 1210.05 1047.53 706.23 465.40 1159.07 1128.79 585.82 4.28 4.58 2.43 -0.95 -1.36 Matched[5510]
YOR233W KIN4 "Serine/threonine protein kinase that inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck" Verified chr15:775847-778249 775847-778249 98.7% 110.51 121.06 89.84 57.79 37.54 23.20 115.78 73.82 30.37 0.43 0.30 0.13 -1.28 -0.96 Matched[5511]
YOR234C RPL33B "Ribosomal protein L37 of the large (60S) ribosomal subunit, nearly identical to Rpl33Ap and has similarity to rat L35a; rpl33b null mutant exhibits normal growth while rpl33a rpl33b double null mutant is inviable" Verified chr15:778556-779406 778556-778860,779388-779406 91.0% 4185.42 3313.74 3449.41 2615.04 773.32 430.75 3749.58 3032.22 602.04 13.84 12.31 2.49 -2.33 -2.76 Matched[5512]
YOR235W Hypothetical protein; null mutant displays increased levels of spontaneous Rad52 foci Dubious chr15:779871-780185 779871-780185 99.5% 0.00 6.38 0.00 3.19 6.38 0.00 3.19 1.60 3.19 0.01 0.01 0.01 1.00 -0.60 Frag<80[5513]
YOR236W DFR1 "Dihydrofolate reductase, part of the dTTP biosynthetic pathway, involved in folate metabolism, possibly required for mitochondrial function" Verified chr15:780907-781542 780907-781542 98.5% 201.12 183.56 204.31 166.00 75.02 38.31 192.34 185.16 56.66 0.71 0.75 0.23 -1.71 -1.55 Matched[5514]
YOR237W HES1 Protein implicated in the regulation of ergosterol biosynthesis; one of a seven member gene family with a common essential function and non-essential unique functions; similar to human oxysterol binding protein (OSBP) Verified chr15:781995-783299 781995-783299 98.4% 7.01 16.35 5.45 3.11 4.67 5.45 11.68 4.28 5.06 0.04 0.02 0.02 0.24 0.53
YOR238W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr15:783678-784589 783678-784589 99.0% 119.63 120.74 90.83 81.97 122.95 77.54 120.18 86.40 100.24 0.44 0.35 0.42 0.21 0.16 Matched[5515]
YOR239W ABP140 "Nonessential protein that binds actin filaments and localizes to actin patches and cables, has similarity to S-adenosylmethionine (AdoMet)-dependent methyltransferases" Verified chr15:784858-786745 784858-786745 98.4% 699.01 600.00 526.28 514.44 355.70 384.75 649.51 520.36 370.22 2.40 2.11 1.53 -0.49 1.10 Covered/w/another[5516]
YOR241W MET7 "Folylpolyglutamate synthetase, catalyzes extension of the glutamate chains of the folate coenzymes, required for methionine synthesis and for maintenance of mitochondrial DNA" Verified chr15:786996-788642 786996-788642 98.8% 226.71 232.85 195.38 160.97 149.30 140.08 229.78 178.17 144.69 0.85 0.72 0.60 -0.30 -0.22 Covered/w/another[5516]
YOR242C SSP2 Sporulation specific protein that localizes to the spore wall; required for sporulation at a point after meiosis II and during spore wall formation; SSP2 expression is induced midway in meiosis Verified chr15:788743-789858 788743-789858 99.4% 28.85 25.24 17.13 7.21 18.03 9.02 27.05 12.17 13.52 0.10 0.05 0.06 0.15 0.67 Frag<80[5517]
YOR243C PUS7 "Pseudouridine synthase, catalyzes pseudouridylation at position 35 in U2 snRNA, position 13 in cytoplasmic tRNAs, and position 35 in pre-tRNA(Tyr); Asp(256) mutation abolishes activity; conserved in archaea, some bacteria, and vertebrates" Verified chr15:790212-792242 790212-792242 99.2% 373.20 202.48 265.01 255.09 37.72 9.43 287.84 260.05 23.57 1.06 1.06 0.10 -3.46 -3.33 Matched[5518]
YOR244W ESA1 Histone acetyltransferase catalytic subunit of the native multisubunit complex (NuA4) that acetylates four conserved internal lysines of histone H4 N-terminal tail; required for cell cycle progression Verified chr15:792532-793869 792532-793869 98.7% 126.42 121.88 121.12 107.50 131.72 96.90 124.15 114.31 114.31 0.46 0.46 0.47 0.00 0.28 Matched[5519]
YOR245C DGA1 "Diacylglycerol acyltransferase, catalyzes the terminal step of triacylglycerol (TAG) formation, acylates diacylglycerol using acyl-CoA as an acyl donor, localized to lipid particles" Verified chr15:794077-795333 794077-795333 99.0% 138.19 154.26 155.87 115.69 351.10 195.23 146.22 135.78 273.17 0.54 0.55 1.13 1.01 1.03 Matched[5520]
YOR246C "Protein with similarity to oxidoreductases, found in lipid particles; required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts" Uncharacterized chr15:795802-796794 795802-796794 98.8% 455.62 404.65 411.79 317.00 236.47 142.70 430.14 364.39 189.59 1.59 1.48 0.79 -0.94 -0.95 Frag>80[5521,5522]
YOR247W SRL1 "Mannoprotein that exhibits a tight association with the cell wall, required for cell wall stability in the absence of GPI-anchored mannoproteins; has a high serine-threonine content; expression is induced in cell wall mutants" Verified chr15:797677-798309 797677-798309 99.3% 3779.68 3587.19 3711.27 3192.68 1282.16 917.88 3683.44 3451.98 1100.02 13.60 14.01 4.56 -1.65 -1.57 Frag>80[5523,5524]
YOR248W "Dubious open reading frame, unlikely to encode a functional protein; based on available experimental and comparative sequence data" Dubious chr15:798014-798316 798014-798316 99.1% 3886.22 3729.71 3909.53 3260.16 1342.03 939.09 3807.96 3584.85 1140.56 14.06 14.55 4.73 -1.65 -1.43 Matched[5524]
YOR249C APC5 "Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" Verified chr15:798675-800732 798675-800732 99.3% 72.89 77.78 65.55 64.57 83.16 63.60 75.34 65.06 73.38 0.28 0.26 0.30 0.17 0.04 Matched[5525]
YOR250C CLP1 "Subunit of cleavage factor I (CFI), involved in both the endonucleolyitc cleavage and polyadenylation steps of mRNA 3'-end maturation" Verified chr15:800971-802308 800971-802308 99.0% 92.84 87.55 79.25 71.70 119.25 98.12 90.19 75.48 108.69 0.33 0.31 0.45 0.53 0.43 Matched[5526]
YOR251C "Putative protein of unknown function with similarity to human thiosulfate sulfurtransferase, an enzyme that catalyzes the transfer of sulfur from thiosulfate to cyanide, forming sulfite and thiocyanate; YOR251C is a non-essential gene" Uncharacterized chr15:802551-803465 802551-803465 98.9% 298.27 266.24 287.23 276.18 223.15 177.86 282.26 281.70 200.51 1.04 1.14 0.83 -0.49 -0.40 Frag>80[5527,5528]
YOR252W TMA16 Protein of unknown function that associates with ribosomes Verified chr15:803668-804204 803668-804204 98.2% 275.01 121.38 166.90 117.59 43.62 18.97 198.20 142.25 31.29 0.73 0.58 0.13 -2.18 -2.03 Matched[5529]
YOR253W NAT5 "Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing" Verified chr15:804378-804908 804378-804908 98.9% 498.65 443.46 492.94 411.10 439.65 359.71 471.05 452.02 399.68 1.74 1.83 1.66 -0.18 -0.66 Matched[5530]
YOR254C SEC63 "Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER" Verified chr15:805033-807024 805033-807024 99.3% 667.65 538.67 605.94 582.17 327.76 225.58 603.16 594.06 276.67 2.23 2.41 1.15 -1.10 -0.73 Frag>80[5530,5531]
YOR255W OSW1 Protein involved in sporulation; required for the construction of the outer spore wall layers; required for proper localization of Spo14p Verified chr15:807272-808108 807272-808108 98.7% 0.00 1.21 1.21 0.00 3.63 6.05 0.61 0.61 4.84 0.00 0.00 0.02 3.00 1.66 Frag<80[5532]
YOR256C TRE2 Protein that functions with Tre1p to regulate ubiquitylation and vacuolar degradation of the metal transporter Smf1p; has similarity to transferrin receptors; inviability of null mutant in systematic studies is due to proximity to CDC31 Verified chr15:808254-810683 808254-810683 99.3% 104.03 120.19 107.34 97.81 142.99 114.39 112.11 102.58 128.69 0.41 0.42 0.53 0.33 0.62 Matched[5533]
YOR257W CDC31 "Calcium-binding component of the spindle pole body (SPB) half-bridge, required for SPB duplication in mitosis and meiosis II; homolog of mammalian centrin; interacts with Kar1p" Verified chr15:811008-811493 811008-811493 98.4% 223.79 263.53 175.69 165.23 328.37 232.16 243.66 170.46 280.26 0.90 0.69 1.16 0.72 0.52 Matched[5534]
YOR258W HNT3 "Member of the third branch of the histidine triad (HIT) superfamily of nucleotide-binding proteins; similar to Aprataxin, a Hint related protein that is mutated in individuals with ataxia with oculomotor apraxia" Verified chr15:811671-812324 811671-812324 98.9% 55.66 51.02 52.57 29.38 94.32 58.76 53.34 40.97 76.54 0.20 0.17 0.32 0.90 0.37 Matched[5535]
YOR259C RPT4 One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for spindle pole body duplication; localized mainly to the nucleus throughout the cell cycle Verified chr15:812395-813708 812395-813708 99.3% 584.08 510.49 583.31 594.81 933.60 624.70 547.28 589.06 779.15 2.02 2.39 3.23 0.40 0.50 Matched[5536]
YOR260W GCD1 "Gamma subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression" Verified chr15:813984-815720 813984-815720 98.9% 348.02 246.17 263.63 207.76 94.86 81.48 297.10 235.70 88.17 1.10 0.96 0.37 -1.42 -0.96 Matched[5537]
YOR261C RPN8 "Essential, non-ATPase regulatory subunit of the 26S proteasome; has similarity to the human p40 proteasomal subunit and to another S. cerevisiae regulatory subunit, Rpn11p" Verified chr15:815915-816931 815915-816931 99.3% 1032.42 878.00 1044.30 924.52 1900.52 1058.15 955.21 984.41 1479.34 3.53 4.00 6.13 0.59 -0.14 Matched[5538]
YOR262W Cytoplasmic protein of unknown function; essential gene with similarity to YLR243W; contains an ATP/GTP binding site motif Uncharacterized chr15:817291-818334 817291-818334 98.5% 159.44 129.30 134.16 77.77 84.58 25.28 144.37 105.97 54.93 0.53 0.43 0.23 -0.95 -1.02 Matched[5539]
YOR264W DSE3 "Daughter cell-specific protein, may help establish daughter fate" Verified chr15:818865-820157 818865-820157 98.8% 212.04 194.82 176.83 136.92 204.99 153.35 203.43 156.88 179.17 0.75 0.64 0.74 0.19 0.58 Frag>80[5540,5541,5542,5543]
YOR263C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF DES3/YOR264W" Dubious chr15:818756-819163 818756-819163 98.6% 149.16 134.24 104.41 77.07 121.81 84.52 141.70 90.74 103.17 0.52 0.37 0.43 0.19 -0.41 Matched[5541]
YOR265W RBL2 "Protein involved in microtubule morphogenesis, required for protection from excess free beta-tubulin; proposed to be involved the folding of beta-tubulin; similar to mouse beta-tubulin cofactor A" Verified chr15:820453-820773 820453-820773 98.5% 360.62 328.98 332.15 278.37 411.23 259.39 344.80 305.26 335.31 1.27 1.24 1.39 0.14 0.01 Matched[5543]
YOR266W PNT1 "Mitochondrial inner membrane protein involved in export of proteins from the mitochondrial matrix; overexpression of PNT1 confers resistance to the anti-Pneumocystis carinii drug pentamidine, and deletion confers increased sensitivity" Verified chr15:821022-822293 821022-822293 98.9% 99.40 96.22 85.88 77.93 65.21 52.49 97.81 81.91 58.85 0.36 0.33 0.24 -0.48 -0.41 Matched[5544]
YOR267C HRK1 Protein kinase implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis Verified chr15:822587-824866 822587-824866 97.1% 188.80 167.57 216.81 224.03 466.59 543.82 178.19 220.42 505.20 0.66 0.89 2.09 1.20 1.81 Matched[5545]
YOR268C Putative protein of unknown function; sporulation is abnormal in homozygous diploid; YOR268C is not an essential gene Uncharacterized chr15:825533-825931 825533-825931 98.4% 0.00 0.00 2.55 0.00 94.26 50.95 0.00 1.27 72.60 0.00 0.01 0.30 5.83 0.12 Matched[5546]
YOR269W PAC1 "Protein involved in nuclear migration, part of the dynein/dynactin pathway; targets dynein to microtubule tips, which is necessary for sliding of microtubules along bud cortex; synthetic lethal with bni1; homolog of human LIS1" Verified chr15:826384-827868 826384-827868 98.9% 57.88 58.56 59.24 40.86 23.15 18.39 58.22 50.05 20.77 0.21 0.20 0.09 -1.27 -0.78 Matched[5547]
YOR270C VPH1 "Subunit a of vacuolar-ATPase V0 domain, one of two isoforms (Vph1p and Stv1p); Vph1p is located in V-ATPase complexes of the vacuole while Stv1p is located in V-ATPase complexes of the Golgi and endosomes" Verified chr15:828051-830573 828051-830573 99.0% 1112.58 1213.47 915.61 853.95 632.56 640.97 1163.03 884.78 636.76 4.29 3.59 2.64 -0.47 -0.04 Covered/w/another[5548]
YOR271C "Putative protein, predicted by computational methods to be an alpha-isopropylmalate carrier; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr15:831058-832041 831058-832041 98.5% 538.51 411.62 426.07 365.20 169.19 140.30 475.07 395.63 154.75 1.75 1.61 0.64 -1.35 -1.29 Covered/w/another[5548]
YOR272W YTM1 "Constituent of 66S pre-ribosomal particles, required for maturation of the large ribosomal subunit" Verified chr15:832812-834194 832812-834194 98.7% 238.79 112.80 139.91 98.89 13.18 5.13 175.80 119.40 9.16 0.65 0.48 0.04 -3.70 0.19 Matched[5550]
YOR273C TPO4 "Polyamine transport protein, recognizes spermine, putrescine, and spermidine; localizes to the plasma membrane; member of the major facilitator superfamily" Verified chr15:834451-836430 834451-836430 98.8% 273.62 149.34 274.13 270.04 763.59 794.78 211.48 272.09 779.18 0.78 1.10 3.23 1.52 1.70 Frag>80[5551,5552]
YOR274W MOD5 "Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase, required for biosynthesis of the modified base isopentenyladenosine in mitochondrial and cytoplasmic tRNAs; gene is nuclear and encodes two isozymic forms" Verified chr15:837673-838959 837673-838959 98.5% 70.18 52.05 57.57 57.57 52.05 37.06 61.11 57.57 44.55 0.23 0.23 0.18 -0.37 -0.01 Covered[5553]
YOR275C RIM20 Protein involved in proteolytic activation of Rim101p in response to alkaline pH; PalA/AIP1/Alix family member; interaction with the ESCRT-III subunit Snf7p suggests a relationship between pH response and multivesicular body formation Verified chr15:839083-841068 839083-841068 99.1% 134.61 153.91 136.14 128.52 201.16 173.22 144.26 132.33 187.19 0.53 0.54 0.78 0.50 0.88 Matched[5554]
YOR276W CAF20 "Phosphoprotein of the mRNA cap-binding complex involved in translational control, repressor of cap-dependent translation initiation, competes with eIF4G for binding to eIF4E" Verified chr15:841332-841817 841332-841817 98.6% 1314.44 1051.55 1368.69 1191.34 477.79 396.42 1183.00 1280.01 437.10 4.37 5.20 1.81 -1.55 -1.65 Matched[5555]
YOR277C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; almost completely overlaps the verified gene CAF20" Dubious chr15:841514-841822 841514-841822 98.5% 1458.73 1186.04 1448.87 1195.89 489.53 410.68 1322.38 1322.38 450.10 4.88 5.37 1.86 -1.55 -0.35 Matched[5555]
YOR278W HEM4 "Uroporphyrinogen III synthase, catalyzes the conversion of hydroxymethylbilane to uroporphyrinogen III, the fourth step in the heme biosynthetic pathway" Verified chr15:842816-843643 842816-843643 98.8% 138.08 150.30 135.63 131.97 182.07 94.09 144.19 133.80 138.08 0.53 0.54 0.57 0.05 -0.08 Covered/w/another[5557]
YOR279C RFM1 DNA-binding protein required for vegetative repression of middle sporulation genes; specificity factor that directs the Hst1p histone deacetylase to some of the promoters regulated by Sum1p; involved in telomere maintenance Verified chr15:843697-844629 843697-844629 99.3% 79.86 70.14 70.14 83.09 99.28 65.83 75.00 76.62 82.55 0.28 0.31 0.34 0.11 -0.08 Covered/w/another[5557]
YOR280C FSH3 Serine hydrolase; sequence is similar to Fsh1p and Fsh2p Verified chr15:844991-845791 844991-845791 99.2% 153.59 152.33 169.95 151.07 195.13 120.86 152.96 160.51 157.99 0.56 0.65 0.65 -0.02 0.25 Covered/w/another[5557]
YOR282W Hypothetical protein; open reading frame overlaps 5' end of essential PLP2 gene Dubious chr15:846999-847319 846999-847319 99.3% 131.71 109.76 125.44 134.85 97.22 53.31 120.74 130.15 75.26 0.45 0.53 0.31 -0.79 -0.41 Frag<80[5559]
YOR281C PLP2 "Essential protein with similarity to phosducins, which are G-protein regulators; lethality of null mutation is functionally complemented by expression of mouse phosducin-like protein MgcPhLP" Verified chr15:846268-847128 846268-847128 99.4% 331.97 278.20 319.11 291.06 220.92 122.74 305.08 305.08 171.83 1.13 1.24 0.71 -0.83 -0.73 Frag>80[5558,5559]
YOR283W "Putative protein of unknown function with some similarity to GPM1/YKL152C, a phosphoglycerate mutase; YOR283W is not an essential gene" Uncharacterized chr15:847452-848144 847452-848144 98.7% 311.52 362.71 261.79 229.62 204.75 96.53 337.11 245.70 150.64 1.24 1.00 0.62 -0.71 -0.75 Matched[5560]
YOR284W HUA2 Cytoplasmic protein of unknown function; computational analysis of large-scale protein-protein interaction data suggests a possible role in actin patch assembly Verified chr15:848477-849208 848477-849208 98.9% 71.85 81.52 93.96 49.74 49.74 27.64 76.69 71.85 38.69 0.28 0.29 0.16 -0.89 -0.21 Matched[5561]
YOR285W "Protein of unknown function, localized to the mitochondrial outer membrane" Verified chr15:849634-850053 849634-850053 98.7% 1526.37 2071.34 1974.88 1753.04 6578.12 3954.59 1798.85 1863.96 5266.35 6.64 7.57 21.82 1.50 0.69 Matched[5562]
YOR286W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr15:850279-850728 850279-850728 98.5% 615.67 541.25 534.49 615.67 753.24 419.47 578.46 575.08 586.36 2.14 2.33 2.43 0.03 -0.21 Matched[5563]
YOR287C Putative protein of unknown function; may play a role in the ribosome and rRNA biosynthesis based on expression profiles and mutant phenotype Uncharacterized chr15:850936-851838 850936-851838 99.5% 102.37 82.34 68.99 77.89 5.56 5.56 92.35 73.44 5.56 0.34 0.30 0.02 -3.72 -3.63 Matched[5564]
YOR288C MPD1 Member of the protein disulfide isomerase (PDI) family; interacts with and inhibits the chaperone activity of Cne1p; MPD1 overexpression in a pdi1 null mutant suppresses defects in Pdi1p functions such as carboxypeptidase Y maturation Verified chr15:852120-853076 852120-853076 99.1% 174.04 164.54 181.42 175.09 745.72 497.85 169.29 178.25 621.78 0.62 0.72 2.58 1.80 1.98 Matched[5565]
YOR289W Hypothetical protein Uncharacterized chr15:853356-854111 853356-854111 98.7% 109.88 155.44 129.98 113.90 929.98 345.73 132.66 121.94 637.86 0.49 0.49 2.64 2.39 1.40 Matched[5566]
YOR290C SNF2 Catalytic subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; contains DNA-stimulated ATPase activity; functions interdependently in transcriptional activation with Snf5p and Snf6p Verified chr15:855146-860257 855146-860257 99.1% 150.59 160.06 138.16 135.59 107.76 170.52 155.33 136.87 139.14 0.57 0.56 0.58 0.02 0.49 Matched[5568]
YOR291W Putative protein of unknown function; shares sequence similarity with the type V P-type ATPase Spf1p; YOR291W is not an essential protein Uncharacterized chr15:861174-865592 861174-865592 98.9% 116.45 154.20 119.19 110.96 99.06 101.35 135.32 115.07 100.20 0.50 0.47 0.42 -0.20 -0.07 Frag>80[5569,5570]
YOR292C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YOR292C is not an essential gene Uncharacterized chr15:865652-866581 865652-866581 99.0% 71.72 106.49 92.36 78.24 334.68 195.59 89.10 85.30 265.13 0.33 0.35 1.10 1.64 1.47 Matched[5571]
YOR293W RPS10A Protein component of the small (40S) ribosomal subunit; nearly identical to Rps10Bp and has similarity to rat ribosomal protein S10 Verified chr15:867097-867851 867097-867148,867586-867851 73.6% 9817.79 8015.66 8643.42 7716.73 1883.27 1516.01 8916.73 8180.07 1699.64 32.92 33.20 7.04 -2.27 -3.00 Matched[5572]
YOR293C-A Identified by expression profiling and mass spectrometry Uncharacterized chr15:867997-868146 867997-868146 99.3% 33.56 0.00 6.71 6.71 13.42 6.71 16.78 6.71 10.07 0.06 0.03 0.04 0.58 NaN Covered/w/another[5572]
YOR294W RRS1 Essential protein that binds ribosomal protein L11 and is required for nuclear export of the 60S pre-ribosomal subunit during ribosome biogenesis; mouse homolog shows altered expression in Huntington's disease model mice Verified chr15:868339-868950 868339-868950 98.3% 347.42 149.61 182.85 109.71 18.29 1.66 248.51 146.28 9.97 0.92 0.59 0.04 -3.87 -3.08 Covered/w/another[5573]
YOR295W UAF30 "Subunit of UAF (upstream activation factor), which is an RNA polymerase I specific transcription stimulatory factor composed of Uaf30p, Rrn5p, Rrn9p, Rrn10p, histones H3 and H4; deletion decreases cellular growth rate" Verified chr15:869207-869893 869207-869893 98.5% 91.65 76.87 73.91 53.22 32.52 11.83 84.26 63.57 22.17 0.31 0.26 0.09 -1.52 -1.74 Covered/w/another[5573]
YOR296W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; expressed during copper starvation; YOR296W is not an essential gene Uncharacterized chr15:870201-874070 870201-874070 98.8% 53.62 59.11 47.34 43.94 38.45 45.25 56.36 45.64 41.85 0.21 0.19 0.17 -0.13 0.27 Covered/w/another[5573]
YOR297C TIM18 Component of the mitochondrial Tim54p-Tim22p complex involved in insertion of polytopic proteins into the inner membrane; may function to stabilize the complex Verified chr15:874742-875320 874742-875320 98.9% 165.84 155.37 158.86 157.11 162.35 75.07 160.61 157.99 118.71 0.59 0.64 0.49 -0.41 -0.25 Frag>80[5574,5575,5576]
YOR298W MUM3 Protein of unknown function involved in the organization of the outer spore wall layers; has similarity to the tafazzins superfamily of acyltransferases Verified chr15:875598-877037 875598-877037 99.0% 57.55 56.14 45.62 37.19 121.41 72.28 56.84 41.40 96.84 0.21 0.17 0.40 1.23 -1.19 Frag>80[5575,5576,5577,5578]
YOR298C-A MBF1 Transcriptional coactivator that bridges the DNA-binding region of Gcn4p and TATA-binding protein Spt15p; suppressor of frameshift mutations Verified chr15:877229-877684 877229-877684 99.2% 2229.63 2269.40 2435.14 2576.56 15165.45 9234.51 2249.52 2505.85 12199.98 8.30 10.17 50.55 2.28 1.19 Frag>80[5578,5579]
YOR299W BUD7 "Member of the Chs5p-Arf1p-binding proteins (ChAPs), a group of 4 related, interacting proteins (Bch1p, Fmp50p, Bud7p, Chs6p) that mediate export of specific cargo proteins, including chitin synthase Chs3p, from the Golgi to plasma membrane" Verified chr15:878433-880673 878433-880673 98.6% 132.56 110.39 125.78 102.70 204.95 171.93 121.48 114.24 188.44 0.45 0.46 0.78 0.72 1.02 Matched[5580]
YOR300W "Dubious open reading frame, unlikely to encode a protein; overlaps with verified gene BUD7/YOR299W; mutation affects bipolar budding and bud site selection, though phenotype could be due to the mutation's effects on BUD7" Dubious chr15:880573-880881 880573-880881 99.0% 88.28 52.32 81.74 32.70 160.22 85.01 70.30 57.22 122.62 0.26 0.23 0.51 1.10 -0.19 Covered/w/another[5581]
YOR301W RAX1 Protein involved in bud site selection during bipolar budding; localization requires Rax2p; has similarity to members of the insulin-related peptide superfamily Verified chr15:880963-882270 880963-882270 98.6% 122.53 122.53 117.88 95.39 104.69 59.71 122.53 106.63 82.20 0.45 0.43 0.34 -0.38 -0.19 Covered/w/another[5581]
YOR302W "CPA1 uORF , Arginine attenuator peptide, regulates translation of the CPA1 mRNA" Verified chr15:882763-882840 882763-882840 99.4% 180.55 490.06 51.59 90.27 25.79 51.59 335.30 70.93 38.69 1.24 0.29 0.16 -0.87 -0.31 Covered/w/another[5581]
YOR303W CPA1 "Small subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor; translationally regulated by an attenuator peptide encoded by YOR302W within the CPA1 mRNA 5'-leader" Verified chr15:882897-884132 882897-884132 99.0% 252.61 483.97 138.16 111.18 93.20 53.14 368.29 124.67 73.17 1.36 0.51 0.30 -0.77 -0.37 Covered/w/another[5581]
YOR304W ISW2 "Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes; ATPase component that, with Itc1p, forms a complex required for repression of a-specific genes, INO1, and early meiotic genes during mitotic growth" Verified chr15:884512-887874 884512-887874 98.6% 152.93 142.68 123.97 102.86 90.79 91.10 147.80 113.42 90.94 0.55 0.46 0.38 -0.32 0.13 Matched[5582]
YOR304C-A "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck" Uncharacterized chr15:888518-888748 888518-888748 99.3% 231.10 239.83 244.19 178.78 130.81 113.37 235.47 211.48 122.09 0.87 0.86 0.51 -0.79 -0.44 Matched[5584]
YOR305W Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO); YOR305W is not an essential gene Uncharacterized chr15:889020-889748 889020-889748 98.8% 306.71 321.98 263.69 251.20 263.69 137.40 314.35 257.45 200.54 1.16 1.05 0.83 -0.36 -0.60 Matched[5585]
YOR306C MCH5 "Plasma membrane riboflavin transporter; facilitates the uptake of vitamin B2; required for FAD-dependent processes; sequence similarity to mammalian monocarboxylate permeases, however mutants are not deficient in monocarboxylate transport" Verified chr15:889865-891430 889865-891430 98.9% 165.36 230.60 126.60 91.72 60.72 47.80 197.98 109.16 54.26 0.73 0.44 0.22 -1.01 -0.34 Covered[5586]
YOR307C SLY41 Protein involved in ER-to-Golgi transport Verified chr15:892728-894089 892728-894089 99.0% 221.81 234.42 192.88 216.62 210.68 221.81 228.12 204.75 216.25 0.84 0.83 0.90 0.08 0.40 Covered/w/another[5587]
YOR308C SNU66 Component of the U4/U6.U5 snRNP complex involved in pre-mRNA splicing via spliceosome; has homology to human SART-1 and to an S. pombe protein; snu66 null mutation confers cold-sensitivity but is not lethal at normal growth temperatures Verified chr15:894621-896384 894621-896384 99.3% 133.01 141.00 110.75 85.63 61.65 77.64 137.01 98.19 69.64 0.51 0.40 0.29 -0.50 -0.37 Covered/w/another[5587]
YOR309C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene NOP58" Dubious chr15:896695-897075 896695-897075 92.0% 2675.86 1606.09 1765.84 1705.93 228.22 77.02 2140.97 1735.89 152.62 7.90 7.05 0.63 -3.51 -2.75 Matched[5588]
YOR310C NOP58 "Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the small subunit processome complex, which is required for processing of pre-18S rRNA" Verified chr15:896822-898357 896822-898357 97.3% 1925.89 1168.38 1266.75 1227.27 153.91 65.58 1547.14 1247.01 109.74 5.71 5.06 0.45 -3.51 -3.49 Frag>80[5588,5589]
YOR311C HSD1 "Endoplasmic reticulum (ER)-resident membrane protein, overproduction induces enlargement of ER-like membrane structures and suppresses a temperature-sensitive sly1 mutation" Verified chr15:899053-899925 899053-899925 98.9% 318.43 347.37 287.16 250.11 223.48 171.37 332.90 268.64 197.42 1.23 1.09 0.82 -0.44 -0.05 Frag>80[5590,5591]
YOR312C RPL20B "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl20Ap and has similarity to rat L18a ribosomal protein" Verified chr15:900247-901191 900247-900764,901191-901191 51.3% 8016.26 6162.31 6526.35 5595.62 1369.82 885.69 7089.29 6060.99 1127.76 26.17 24.60 4.67 -2.43 -3.49 Matched[5592]
YOR313C SPS4 Protein whose expression is induced during sporulation; not required for sporulation; heterologous expression in E. coli induces the SOS response that senses DNA damage Verified chr15:901855-902871 901855-902871 99.4% 77.17 70.24 75.19 51.45 14.84 4.95 73.71 63.32 9.89 0.27 0.26 0.04 -2.68 -3.09 Matched[5593]
YOR314W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr15:903040-903369 903040-903369 98.8% 33.75 27.61 42.96 27.61 9.20 6.14 30.68 35.29 7.67 0.11 0.14 0.03 -2.20 0.27 Covered/w/another[5593]
YOR314W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr15:904455-904565 904455-904565 99.6% 9.05 0.00 9.05 0.00 0.00 27.14 4.52 4.52 13.57 0.02 0.02 0.06 1.58 -0.08 Matched[5594]
YOR315W SFG1 "Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (which do not invade the agar substrate) but not for invasive pseudohyphal growth; may act together with Phd1p; potential Cdc28p substrate" Verified chr15:904757-905797 904757-905797 98.9% 624.52 563.33 481.75 462.32 42.74 17.48 593.93 472.04 30.11 2.19 1.92 0.12 -3.97 -3.38 Matched[5595]
YOR316C COT1 Vacuolar transporter that mediates zinc transport into the vacuole; overexpression confers resistance to cobalt and rhodium Verified chr15:906233-907552 906233-907552 98.8% 180.24 167.20 219.35 155.69 282.24 253.87 173.72 187.52 268.06 0.64 0.76 1.11 0.52 0.67 Matched[5596]
YOR316C-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr15:907723-907932 907723-907932 98.0% 14.58 14.58 9.72 29.17 0.00 0.00 14.58 19.45 0.00 0.05 0.08 0.00 -Inf NaN Covered[5597]
YOR317W FAA1 Long chain fatty acyl-CoA synthetase with a preference for C12:0-C16:0 fatty acids; involved in the activation of imported fatty acids; localized to both lipid particles and mitochondrial outer membrane; essential for stationary phase Verified chr15:909340-911442 909340-911442 98.2% 414.56 554.52 592.30 711.44 2200.66 2477.20 484.54 651.87 2338.93 1.79 2.65 9.69 1.84 1.47 Matched[5598]
YOR318C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo" Dubious chr15:911781-912433 911781-912082,912430-912433 98.7% 26.48 19.86 29.78 16.55 36.40 26.48 23.17 23.17 31.44 0.09 0.09 0.13 0.44 0.06 Matched[5599]
YOR319W HSH49 U2-snRNP associated splicing factor with similarity to the mammalian splicing factor SAP49; proposed to function as a U2-snRNP assembly factor along with Hsh155p and binding partner Cus1p; contains two RNA recognition motifs (RRM) Verified chr15:912819-913460 912819-913460 99.0% 138.41 144.70 133.69 72.35 135.26 67.63 141.56 103.02 101.45 0.52 0.42 0.42 -0.02 -0.13 Matched[5600]
YOR320C GNT1 N-acetylglucosaminyltransferase capable of modification of N-linked glycans in the Golgi apparatus Verified chr15:913616-915091 913616-915091 99.3% 270.28 316.01 247.07 213.63 212.26 139.23 293.14 230.35 175.75 1.08 0.94 0.73 -0.39 -0.26 Matched[5601]
YOR321W PMT3 "Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt5p, can instead interact with Pmt1p in some conditions; target for new antifungals" Verified chr15:916027-918288 916027-918288 98.8% 134.29 144.13 135.18 116.38 123.54 112.80 139.21 125.78 118.17 0.51 0.51 0.49 -0.09 0.32 Frag>80[5602,5603]
YOR322C LDB19 Protein of unknown function involved in maintenance of proper telomere length; null mutant shows a reduced affinity for the alcian blue dye suggesting a decreased net negative charge of the cell surface Verified chr15:918603-921059 918603-921059 98.8% 135.51 126.04 128.51 107.92 100.91 93.09 130.78 118.21 97.00 0.48 0.48 0.40 -0.29 0.26 Matched[5604]
YOR323C PRO2 "Gamma-glutamyl phosphate reductase, catalyzes the second step in proline biosynthesis" Verified chr15:921532-922902 921532-922902 99.1% 469.38 457.61 430.38 386.98 289.87 267.06 463.49 408.68 278.46 1.71 1.66 1.15 -0.55 0.03 Matched[5605]
YOR325W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified ORF FRT1" Dubious chr15:924574-925047 924574-925047 98.9% 76.81 93.88 61.88 70.41 44.81 32.01 85.35 66.15 38.41 0.32 0.27 0.16 -0.78 -0.18 Covered/w/another[5606]
YOR324C FRT1 "Tail-anchored endoplasmic reticulum membrane protein that is a substrate of the phosphatase calcineurin, interacts with homolog Frt2p, promotes cell growth in conditions of high Na+, alkaline pH, and cell wall stress" Verified chr15:923229-925037 923229-925037 98.9% 116.81 148.67 84.95 92.78 60.92 59.24 132.74 88.86 60.08 0.49 0.36 0.25 -0.56 -0.19 Matched[5606]
YOR326W MYO2 "One of two type V myosin motors (along with MYO4) involved in actin-based transport of cargos; required for the polarized delivery of secretory vesicles, the vacuole, late Golgi elements, peroxisomes, and the mitotic spindle" Verified chr15:925718-930442 925718-930442 98.8% 455.50 433.65 382.87 370.02 233.32 350.52 444.58 376.44 291.92 1.64 1.53 1.21 -0.37 0.27 Frag>80[5607,5608,5609]
YOR327C SNC2 Vesicle membrane receptor protein (v-SNARE) involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane; member of the synaptobrevin/VAMP family of R-type v-SNARE proteins Verified chr15:930731-931078 930731-931078 99.2% 738.86 634.55 680.91 704.09 1121.33 837.38 686.71 692.50 979.36 2.53 2.81 4.06 0.50 0.71 Matched[5610]
YOR328W PDR10 "ATP-binding cassette (ABC) transporter, multidrug transporter involved in the pleiotropic drug resistance network; regulated by Pdr1p and Pdr3p" Verified chr15:931800-936494 931800-936494 98.6% 18.80 24.85 15.78 11.24 25.72 24.64 21.83 13.51 25.18 0.08 0.05 0.10 0.90 1.21 Frag<80[5611]
YOR329W-A "Dubious open reading frame, unlikely to encode a functional protein; identified by fungal homology and RT-PCR" Dubious chr15:939345-939554 939345-939554 99.1% 48.07 48.07 38.45 33.65 72.10 52.87 48.07 36.05 62.49 0.18 0.15 0.26 0.79 NaN Covered/w/another[5612]
YOR329C SCD5 Protein required for normal cortical actin organization and endocytosis; multicopy suppressor of clathrin deficiency; acts as a targeting subunit for protein phosphatase type 1 Verified chr15:936728-939346 936728-939346 98.8% 168.88 195.16 189.36 157.29 192.07 127.14 182.02 173.32 159.61 0.67 0.70 0.66 -0.12 0.18 Matched[5612]
YOR330C MIP1 Catalytic subunit of the mitochondrial DNA polymerase; conserved C-terminal segment is required for the maintenance of mitochondrial genome. Verified chr15:939618-943382 939618-943382 99.1% 106.40 121.14 95.95 84.96 75.58 74.51 113.77 90.45 75.04 0.42 0.37 0.31 -0.27 0.17 Matched[5613]
YOR332W VMA4 "Subunit E of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane" Verified chr15:943653-944354 943653-944354 98.2% 2514.87 3393.76 2558.38 2435.10 2757.07 2226.25 2954.31 2496.74 2491.66 10.91 10.13 10.32 -0.00 -0.29 Matched[5614]
YOR331C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; open reading frame overlaps the verified gene VMA4/YOR332W" Dubious chr15:943562-944119 943562-944119 98.1% 2164.71 2824.17 2161.06 2106.26 2241.44 1945.50 2494.44 2133.66 2093.47 9.21 8.66 8.67 -0.03 0.01 Matched[5614]
YOR334W MRS2 "Mitochondrial inner membrane Mg(2+) channel, required for maintenance of intramitochondrial Mg(2+) concentrations at the correct level to support splicing of group II introns" Verified chr15:944593-946005 944593-946005 99.0% 79.38 97.97 67.22 48.63 58.64 57.92 88.67 57.92 58.28 0.33 0.24 0.24 0.01 -0.13 Matched[5615]
YOR333C "Dubious open reading frame, unlikely to encode a functional protein; overlaps 5' end of MRS2 gene required for respiratory growth" Dubious chr15:944538-944954 944538-944954 99.3% 74.87 60.38 67.63 45.89 24.15 62.80 67.63 56.76 43.47 0.25 0.23 0.18 -0.38 0.14 Covered/w/another[5615]
YOR335W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene ALA1/YOR335C" Dubious chr15:946565-946645 946565-946645 99.9% 815.23 691.71 765.83 827.59 111.17 98.82 753.47 796.71 104.99 2.78 3.23 0.44 -2.92 NaN Covered/w/another[5616]
YOR335C ALA1 "Cytoplasmic alanyl-tRNA synthetase, required for protein synthesis; point mutation (cdc64-1 allele) causes cell cycle arrest at G1; lethality of null mutation is functionally complemented by human homolog" Verified chr15:946230-949106 946230-949106 99.0% 509.55 360.75 480.42 426.03 88.08 77.20 435.15 453.22 82.64 1.61 1.84 0.34 -2.46 -2.02 Matched[5616]
YOR336W KRE5 "Protein required for beta-1,6 glucan biosynthesis; mutations result in aberrant morphology and severe growth defects" Verified chr15:949770-953867 949770-953867 98.9% 98.16 97.91 76.95 77.94 58.21 62.15 98.04 77.44 60.18 0.36 0.31 0.25 -0.36 0.32 Matched[5617]
YOR337W TEA1 Ty1 enhancer activator required for full levels of Ty enhancer-mediated transcription; C6 zinc cluster DNA-binding protein Verified chr15:954341-956620 954341-956620 98.7% 70.20 68.42 38.66 32.43 12.00 10.22 69.31 35.55 11.11 0.26 0.14 0.05 -1.68 -0.92 Matched[5618]
YOR338W Putative protein of unknown function; YOR338W transcription is regulated by Azf1p and its transcript is a specific target of the G protein effector Scp160p; identified as being required for sporulation in a high-throughput mutant screen Uncharacterized chr15:956895-957986 956895-957986 98.5% 5.58 7.43 2.79 0.00 11.15 13.01 6.50 1.39 12.08 0.02 0.01 0.05 3.12 1.15 Frag<80[5619]
YOR339C UBC11 "Ubiquitin-conjugating enzyme most similar in sequence to Xenopus ubiquitin-conjugating enzyme E2-C, but not a true functional homolog of this E2; unlike E2-C, not required for the degradation of mitotic cyclin Clb2" Verified chr15:958359-958829 958359-958829 99.2% 19.27 14.99 12.85 12.85 19.27 14.99 17.13 12.85 17.13 0.06 0.05 0.07 0.42 -0.89
YOR340C RPA43 RNA polymerase I subunit A43 Verified chr15:959199-960179 959199-960179 99.2% 371.85 236.26 251.67 221.88 28.76 6.16 304.06 236.77 17.46 1.12 0.96 0.07 -3.76 -4.60 Matched[5620]
YOR341W RPA190 RNA polymerase I subunit; largest subunit of RNA polymerase I Verified chr15:960984-965978 960984-965978 98.8% 360.95 197.49 227.06 183.92 25.52 15.80 279.22 205.49 20.66 1.03 0.83 0.09 -3.31 -2.32 Frag<80[5621]
YOR342C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus Uncharacterized chr15:966663-967622 966663-967622 98.9% 348.50 322.18 344.29 252.69 60.01 48.43 335.34 298.49 54.22 1.24 1.21 0.22 -2.46 -1.79 Covered/w/another[5622]
YOR343C "Dubious open reading frame, unlikely to encode a functional protein; based on available experimental and comparative sequence data" Dubious chr15:968145-968471 968145-968471 97.9% 24.98 81.18 31.22 15.61 15.61 12.49 53.08 23.42 14.05 0.20 0.10 0.06 -0.74 -0.37 Covered/w/another[5622]
YOR344C TYE7 Serine-rich protein that contains a basic-helix-loop-helix (bHLH) DNA binding motif; binds E-boxes of glycolytic genes and contributes to their activation; may function as a transcriptional activator in Ty1-mediated gene expression Verified chr15:977191-978066 977191-978066 99.0% 715.99 977.71 532.67 578.79 470.41 457.72 846.85 555.73 464.07 3.13 2.26 1.92 -0.26 0.27 Matched[5627]
YOR346W REV1 "Deoxycytidyl transferase, forms a complex with the subunits of DNA polymerase zeta, Rev3p and Rev7p; involved in repair of abasic sites in damaged DNA" Verified chr15:981825-984782 981825-984782 98.9% 198.69 148.08 139.19 117.64 93.36 64.29 173.39 128.41 78.83 0.64 0.52 0.33 -0.70 -1.52 Frag>80[5630,5631]
YOR345C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; open reading frame overlaps the verified gene REV1" Dubious chr15:981809-982159 981809-982159 98.8% 95.11 86.47 40.35 37.47 11.53 28.82 90.79 38.91 20.18 0.34 0.16 0.08 -0.95 -1.13 Covered/w/another[5630]
YOR347C PYK2 "Pyruvate kinase that appears to be modulated by phosphorylation; PYK2 transcription is repressed by glucose, and Pyk2p may be active under low glycolytic flux" Verified chr15:984939-986459 984939-986459 98.9% 126.35 172.91 212.81 236.08 727.53 720.88 149.63 224.45 724.21 0.55 0.91 3.00 1.69 1.49 Matched[5632]
YOR348C PUT4 "Proline permease, required for high-affinity transport of proline; also transports the toxic proline analog azetidine-2-carboxylate (AzC); PUT4 transcription is repressed in ammonia-grown cells" Verified chr15:986896-988779 986896-988779 98.3% 4.32 5.94 8.64 13.50 15.12 12.42 5.13 11.07 13.77 0.02 0.04 0.06 0.31 0.45 Frag<80[5633]
YOR349W CIN1 Tubulin folding factor D involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl Verified chr15:989786-992830 989786-992830 99.2% 35.77 28.81 20.20 12.92 16.89 15.90 32.29 16.56 16.39 0.12 0.07 0.07 -0.01 0.15 Frag<80[5634]
YOR350C MNE1 Mitochondrial protein similar to Lucilia illustris mitochondrial cytochrome oxidase Verified chr15:992861-994852 992861-994852 99.1% 54.20 66.86 48.12 60.27 77.50 49.64 60.53 54.20 63.57 0.22 0.22 0.26 0.23 0.43 Matched[5635]
YOR351C MEK1 "Meiosis-specific serine/threonine protein kinase, functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids" Verified chr15:995015-996508 995015-996508 99.2% 12.82 14.17 8.77 8.77 11.47 7.42 13.49 8.77 9.45 0.05 0.04 0.04 0.11 3.52
YOR352W "Putative protein of unknown function; expression levels regulated by Arg5,6p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus" Uncharacterized chr15:997210-998241 997210-998241 99.0% 110.56 114.47 138.93 143.82 246.56 183.94 112.52 141.38 215.25 0.42 0.57 0.89 0.61 0.87 Covered/w/another[5636]
YOR353C SOG2 "Key component of the RAM signaling network, required for proper cell morphogenesis and cell separation after mitosis" Verified chr15:998450-1000825 998450-1000825 99.2% 97.97 89.07 81.43 77.19 86.95 74.22 93.52 79.31 80.59 0.35 0.32 0.33 0.02 0.47 Covered/w/another[5636]
YOR354C MSC6 "Protein of unknown function; mutant is defective in directing meiotic recombination events to homologous chromatids; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr15:1001144-1003222 1001144-1003222 99.1% 211.53 207.65 228.51 236.75 163.98 126.62 209.59 232.63 145.30 0.77 0.94 0.60 -0.68 -0.11 Matched[5637]
YOR355W GDS1 "Protein of unknown function, required for growth on glycerol as a carbon source; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr15:1005135-1006703 1005135-1006703 99.0% 527.78 446.04 485.30 281.27 129.37 120.36 486.91 383.29 124.87 1.80 1.56 0.52 -1.62 -0.89 Covered[5638]
YOR356W Mitochondrial protein with similarity to flavoprotein-type oxidoreductases; found in a large supramolecular complex with other mitochondrial dehydrogenases Verified chr15:1007219-1009114 1007219-1009114 98.4% 185.96 224.00 216.50 221.86 224.00 232.58 204.98 219.18 228.29 0.76 0.89 0.95 0.06 0.43 Matched[5639]
YOR357C SNX3 Sorting nexin required to maintain late-Golgi resident enzymes in their proper location by recycling molecules from the prevacuolar compartment; contains a PX domain and sequence similarity to human Snx3p Verified chr15:1009222-1009710 1009222-1009710 99.1% 245.47 319.72 270.22 208.34 746.71 426.99 282.60 239.28 586.85 1.04 0.97 2.43 1.29 0.59 Covered/w/another[5639]
YOR358W HAP5 "Subunit of the heme-activated, glucose-repressed Hap2/3/4/5 CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; required for assembly and DNA binding activity of the complex" Verified chr15:1010159-1010887 1010159-1010887 97.9% 89.69 114.92 116.32 106.51 210.22 134.54 102.31 111.42 172.38 0.38 0.45 0.71 0.63 0.72 Matched[5640]
YOR359W VTS1 "Post-transcriptional gene regulator, RNA-binding protein containing a SAM domain; shows genetic interactions with Vti1p, which is a v-SNARE involved in cis-Golgi membrane traffic" Verified chr15:1011187-1012758 1011187-1012758 99.0% 138.22 135.00 95.15 66.22 14.14 5.79 136.61 80.68 9.96 0.50 0.33 0.04 -3.02 -2.67 Matched[5641]
YOR360C PDE2 "High-affinity cyclic AMP phosphodiesterase, component of the cAMP-dependent protein kinase signaling system, protects the cell from extracellular cAMP, contains readthrough motif surrounding termination codon" Verified chr15:1013239-1014819 1013239-1014819 99.2% 161.95 200.84 161.95 163.23 221.89 156.85 181.40 162.59 189.37 0.67 0.66 0.78 0.22 0.53 Matched[5642]
YOR361C PRT1 "Subunit of the core complex of translation initiation factor 3(eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes" Verified chr15:1015359-1017650 1015359-1017650 99.0% 740.08 515.28 653.25 613.58 163.97 124.74 627.68 633.41 144.36 2.32 2.57 0.60 -2.13 -1.59 Frag>80[5643,5644]
YOR362C PRE10 20S proteasome alpha-type subunit Verified chr15:1017878-1018744 1017878-1018744 99.0% 864.72 779.64 950.96 897.35 1640.87 970.77 822.18 924.15 1305.82 3.04 3.75 5.41 0.50 0.30 Matched[5645]
YOR363C PIP2 "Autoregulatory oleate-specific transcriptional activator of peroxisome proliferation, contains Zn(2)-Cys(6) cluster domain, forms heterodimer with Oaf1p, binds oleate response elements (OREs), activates beta-oxidation genes" Verified chr15:1020220-1023210 1020220-1023210 99.0% 57.06 77.32 49.29 50.31 55.37 67.19 67.19 49.80 61.28 0.25 0.20 0.25 0.30 0.87 Matched[5647]
YOR364W Hypothetical protein Dubious chr15:1023369-1023737 1023369-1023737 99.1% 19.15 5.47 21.89 19.15 38.30 21.89 12.31 20.52 30.10 0.05 0.08 0.12 0.55 0.04 Overlap[5648]
YOR366W Hypothetical protein Dubious chr15:1025254-1025607 1025254-1025607 98.5% 20.08 43.04 8.61 11.48 17.21 25.82 31.56 10.04 21.52 0.12 0.04 0.09 1.10 0.73
YOR365C Putative protein of unknown function; YOR365C is not an essential protein Uncharacterized chr15:1023459-1025570 1023459-1025570 99.0% 28.21 28.21 17.22 10.52 38.73 33.95 28.21 13.87 36.34 0.10 0.06 0.15 1.39 0.55 Frag<80[5648]
YOR367W SCP1 "Component of yeast cortical actin cytoskeleton, binds and cross links actin filaments; originally identified by its homology to calponin (contains a calponin-like repeat) but the Scp1p domain structure is more similar to transgelin" Verified chr15:1026005-1026607 1026005-1026607 98.8% 216.59 196.45 224.99 248.50 523.86 374.42 206.52 236.74 449.14 0.76 0.96 1.86 0.92 0.74 Matched[5649]
YOR368W RAD17 "Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; with Mec3p and Ddc1p, forms a clamp that is loaded onto partial duplex DNA; homolog of human and S. pombe Rad1 and U. maydis Rec1 proteins" Verified chr15:1026841-1028046 1026841-1028046 98.7% 111.69 111.69 100.77 78.94 82.30 41.15 111.69 89.86 61.72 0.41 0.36 0.26 -0.54 -0.90 Matched[5650]
YOR369C RPS12 Protein component of the small (40S) ribosomal subunit; has similarity to rat ribosomal protein S12 Verified chr15:1028192-1028623 1028192-1028623 99.5% 20331.69 16309.57 18206.58 15553.10 6836.19 5497.82 18320.63 16879.84 6167.01 67.63 68.52 25.55 -1.45 -2.81 Matched[5651]
YOR370C MRS6 "Rab escort protein, forms a complex with the Ras-like small GTPase Ypt1p that is required for the prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p)" Verified chr15:1029181-1030992 1029181-1030992 99.0% 522.82 480.46 469.87 430.29 245.24 213.47 501.64 450.08 229.36 1.85 1.83 0.95 -0.97 -0.67 Frag>80[5652,5653]
YOR371C GPB1 "Proposed beta subunit of the heterotrimeric G protein; interacts with the receptor Grp1p, affects signaling by altering the level of phosphorylation of PKS substrates; regulates pseudohyphal growth through cAMP levels; homolog of Gpb2p" Verified chr15:1031487-1034180 1031487-1034180 99.0% 86.25 91.12 81.37 74.25 50.62 91.12 88.68 77.81 70.87 0.33 0.32 0.29 -0.13 0.62 Matched[5654]
YOR372C NDD1 Transcriptional activator essential for nuclear division; localized to the nucleus; essential component of the mechanism that activates the expression of a set of late-S-phase-specific genes Verified chr15:1034805-1036469 1034805-1036469 97.7% 166.52 174.51 154.84 128.42 165.29 148.08 170.51 141.63 156.69 0.63 0.57 0.65 0.15 0.76 Matched[5656]
YOR373W NUD1 "Component of the spindle pole body outer plaque, required for exit from mitosis" Verified chr15:1036832-1039387 1036832-1039387 97.6% 98.61 95.41 80.57 58.93 65.74 42.09 97.01 69.75 53.92 0.36 0.28 0.22 -0.37 -0.12 Frag>80[5657,5658]
YOR374W ALD4 "Mitochondrial aldehyde dehydrogenase, required for growth on ethanol and conversion of acetaldehyde to acetate; phosphorylated; activity is K+ dependent; utilizes NADP+ or NAD+ equally as coenzymes; expression is glucose repressed" Verified chr15:1039838-1041397 1039838-1041397 98.5% 263.54 521.22 1153.05 1229.83 7053.01 4986.36 392.38 1191.44 6019.68 1.45 4.84 24.94 2.34 1.74 Matched[5659]
YOR375C GDH1 "NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh3p; expression regulated by nitrogen and carbon sources" Verified chr15:1041676-1043040 1041676-1043040 97.9% 3893.04 2467.46 4074.79 3889.30 1758.41 1779.36 3180.25 3982.05 1768.89 11.74 16.16 7.33 -1.17 -0.38 Frag>80[5660,5661,5662]
YOR376W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YOR376W is not an essential gene." Dubious chr15:1043189-1043557 1043189-1043557 98.6% 0.00 8.25 5.50 5.50 13.75 5.50 4.12 5.50 9.62 0.02 0.02 0.04 0.81 -0.31 Frag<80[5662]
YOR376W-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr15:1045194-1045349 1045194-1045349 98.7% 38.97 90.93 38.97 32.48 207.85 188.36 64.95 35.72 198.11 0.24 0.15 0.82 2.47 NaN Covered/w/another[5663]
YOR377W ATF1 Alcohol acetyltransferase with potential roles in lipid and sterol metabolism; responsible for the major part of volatile acetate ester production during fermentation Verified chr15:1046224-1047801 1046224-1047801 98.9% 114.10 148.71 114.10 97.43 172.43 130.76 131.40 105.76 151.59 0.49 0.43 0.63 0.52 0.95 Covered/w/another[5663]
YOR378W Putative protein of unknown function; belongs to the DHA2 family of drug:H+ antiporters; YOR378W is not an essential gene Uncharacterized chr15:1049509-1051056 1049509-1051056 98.8% 20.28 28.78 11.12 19.62 22.89 29.43 24.53 15.37 26.16 0.09 0.06 0.11 0.77 1.64 Covered/w/another[5664]
YOR379C Hypothetical protein Dubious chr15:1050724-1051062 1050724-1051062 98.6% 11.96 26.91 5.98 11.96 26.91 14.95 19.44 8.97 20.93 0.07 0.04 0.09 1.22 0.89 Covered/w/another[5664]
YOR380W RDR1 Transcriptional repressor involved in the control of multidrug resistance; negatively regulates expression of the PDR5 gene; member of the Gal4p family of zinc cluster proteins Verified chr15:1051288-1052928 1051288-1052928 98.7% 63.56 61.71 61.10 33.94 83.31 62.95 62.64 47.52 73.13 0.23 0.19 0.30 0.62 0.44 Covered/w/another[5664]
YOR381W FRE3 "Ferric reductase, reduces siderophore-bound iron prior to uptake by transporters; expression induced by low iron levels" Verified chr15:1055543-1057678 1055543-1057678 96.4% 39.33 50.01 45.64 35.44 71.37 51.95 44.67 40.54 61.66 0.16 0.16 0.26 0.60 1.02 Covered[5665]
YOR381W-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr15:1058421-1058588 1058421-1058588 98.7% 6.03 12.06 6.03 0.00 6.03 6.03 9.04 3.01 6.03 0.03 0.01 0.02 1.00 NaN Overlap[5665]
YOR382W FIT2 "Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall" Verified chr15:1059529-1059990 1059529-1059990 98.6% 116.39 278.89 147.13 105.41 1743.62 1297.83 197.64 126.27 1520.72 0.73 0.51 6.30 3.59 2.62 Matched[5666]
YOR383C FIT3 "Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall" Verified chr15:1060439-1061053 1060439-1061053 86.4% 291.54 631.97 349.84 216.30 1085.27 878.37 461.76 283.07 981.82 1.70 1.15 4.07 1.79 1.92 Frag>80[5667,5668]
YOR384W FRE5 "Putative ferric reductase with similarity to Fre2p; expression induced by low iron levels; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr15:1061562-1063646 1061562-1063646 98.5% 69.62 75.46 61.83 64.27 59.40 79.85 72.54 63.05 69.62 0.27 0.26 0.29 0.14 1.43 Covered/w/another[5669]
YOR385W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YOR385W is not an essential gene Uncharacterized chr15:1065041-1065913 1065041-1065913 98.9% 86.84 79.89 75.26 64.84 132.00 94.94 83.37 70.05 113.47 0.31 0.28 0.47 0.70 0.75 Covered/w/another[5669]
YOR386W PHR1 "DNA photolyase involved in photoreactivation, repairs pyrimidine dimers in the presence of visible light; induced by DNA damage; regulated by transcriptional repressor Rph1p" Verified chr15:1066837-1068534 1066837-1068534 98.9% 65.52 105.43 90.53 103.64 285.30 316.28 85.47 97.09 300.79 0.32 0.39 1.25 1.63 1.72 Matched[5670]
YOR387C Putative protein of unknown function; regulated by the metal-responsive Aft1p transcription factor; highly inducible in zinc-depleted conditions; localizes to the soluble fraction Uncharacterized chr15:1069619-1070239 1069619-1070239 61.9% 54.63 85.84 54.63 36.42 192.50 88.45 70.24 45.52 140.47 0.26 0.18 0.58 1.63 0.54 Covered[5671]
YOR388C FDH1 "NAD(+)-dependent formate dehydrogenase, may protect cells from exogenous formate" Verified chr15:1071791-1072921 1071791-1072921 3.6% 0.00 0.00 0.00 0.00 24.51 24.51 0.00 0.00 24.51 0.00 0.00 0.10 Inf 0.75
YOR389W Putative protein of unknown function; expression regulated by copper levels Uncharacterized chr15:1074211-1076085 1074211-1076085 23.5% 29.52 52.23 11.36 9.08 20.44 27.25 40.88 10.22 23.85 0.15 0.04 0.10 1.22 0.92 Overlap[5673]
YOR390W Putative protein of unknown function Uncharacterized chr15:1076782-1077909 1076782-1077909 6.7% 66.26 53.01 185.53 79.51 13.25 39.76 59.64 132.52 26.50 0.22 0.54 0.11 -2.32 -0.31 Frag<80[5674]
YOR391C HSP33 "Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S. cerevisiae Hsp31p, Hsp32p, and Sno4p; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease" Verified chr15:1078543-1079256 1078543-1079256 4.0% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN 2.62
YOR392W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; gene expression induced by heat" Dubious chr15:1079280-1079723 1079280-1079723 18.9% 0.00 0.00 0.00 0.00 0.00 11.92 0.00 0.00 5.96 0.00 0.00 0.02 Inf 1.66
YOR393W ERR1 "Protein of unknown function, has similarity to enolases" Verified chr15:1080274-1081587 1080274-1081587 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 2.00
YOR394W Hypothetical protein Uncharacterized chr15:1082716-1083210 1082716-1083210 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.84
YOR394C-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr15:1084200-1084367 1084200-1084367 2.0% 0.00 0.00 0.00 0.00 0.00 300.00 0.00 0.00 150.00 0.00 0.00 0.62 Inf NaN
YOR396W YRF1-8 "One of several telomeric Y' element-encoded DNA helicases, known as Y'-Help1 (Y'-HELicase Protein 1)" Uncharacterized chr15:1085471-1090861 1085471-1090861 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.30
YOR396C-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr15:1090013-1090495 1090013-1090495 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YPL283W-B "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr16:643-1125 643-1125 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YPL283W-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr16:1426-2001 1426-2001 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
YPL283C YRF1-7 "Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p" Verified chr16:280-6007 280-5840,5989-6007 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.18
YPL282C Hypothetical protein Uncharacterized chr16:7933-8427 7933-8427 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 0.85
YPL281C ERR2 "Protein of unknown function, has similarity to enolases" Verified chr16:9557-10870 9557-10870 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 1.87
YPL280W HSP32 "Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S. cerevisiae Hsp31p, Hsp33p, and Sno4p; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease" Uncharacterized chr16:11887-12600 11887-12600 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN 2.47
YPL279C Putative protein of unknown function Uncharacterized chr16:13228-14355 13228-14355 5.5% 31.96 79.89 143.81 15.98 15.98 47.94 55.93 79.89 31.96 0.21 0.32 0.13 -1.32 -0.32 Frag<80[5675,5676,5677]
YPL278C Putative protein of unknown function; gene expression regulated by copper levels Uncharacterized chr16:15053-15355 15053-15355 1.4% 0.00 233.01 0.00 233.01 466.02 466.02 116.50 116.50 466.02 0.43 0.47 1.93 2.00 1.33 Frag<80[5677,5678]
YPL277C Putative protein of unknown function; localized to the membranes; gene expression regulated by copper levels Uncharacterized chr16:15405-16868 15405-16868 25.4% 45.69 29.57 26.88 24.19 48.38 59.13 37.63 25.53 53.76 0.14 0.10 0.22 1.07 1.21 Frag<80[5677,5678]
YPL274W SAM3 "High-affinity S-adenosylmethionine permease, required for utilization of S-adenosylmethionine as a sulfur source; has similarity to S-methylmethionine permease Mmp1p" Verified chr16:22938-24701 22938-24701 98.8% 142.80 258.65 147.39 108.97 69.97 55.06 200.73 128.18 62.51 0.74 0.52 0.26 -1.04 -0.36 Frag>80[5680,5681]
YPL273W SAM4 "S-adenosylmethionine-homocysteine methyltransferase, functions along with Mht1p in the conversion of S-adenosylmethionine (AdoMet) to methionine to control the methionine/AdoMet ratio" Verified chr16:25087-26064 25087-26064 69.8% 918.06 796.53 726.25 790.68 184.49 165.46 857.30 758.47 174.97 3.16 3.08 0.72 -2.12 -1.88 Frag>80[5681,5682,5683]
YPL272C Putative protein of unknown function; gene expression induced in response to ketoconazole; YPL272C is not an essential gene Uncharacterized chr16:26611-28164 26611-28164 99.1% 36.35 45.44 22.72 20.12 21.42 9.74 40.90 21.42 15.58 0.15 0.09 0.06 -0.46 -0.63
YPL271W ATP15 "Epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated" Verified chr16:30079-30267 30079-30267 99.2% 938.46 1023.77 1114.42 1098.42 1866.25 1221.06 981.12 1106.42 1543.66 3.62 4.49 6.40 0.48 -0.39 Matched[5684]
YPL270W MDL2 Mitochondrial inner membrane half-type ATP-binding cassette (ABC) transporter Verified chr16:30482-32803 30482-32803 98.8% 145.96 171.23 162.52 156.42 181.25 159.90 158.59 159.47 170.58 0.59 0.65 0.71 0.10 0.52 Matched[5685]
YPL269W KAR9 "Karyogamy protein required for correct positioning of the mitotic spindle and for orienting cytoplasmic microtubules, localizes at the shmoo tip in mating cells and at the tip of the growing bud in small-budded cells through anaphase" Verified chr16:33013-34947 33013-34947 98.8% 79.49 106.69 67.46 64.32 56.48 41.84 93.09 65.89 49.16 0.34 0.27 0.20 -0.42 0.17 Matched[5686]
YPL268W PLC1 "Phosphoinositide-specific phospholipase C, hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG); involved in kinetochore function and pseudohyphal differentiation" Verified chr16:35236-37845 35236-37845 98.7% 109.05 133.88 92.36 81.49 74.90 55.88 121.46 86.93 65.39 0.45 0.35 0.27 -0.41 0.00 Matched[5687]
YPL267W ACM1 Cell cycle regulated protein of unknown function; associated with Cdh1p and may supress the APC/C[Cdh1]-mediated proteolysis of mitotic cyclins Verified chr16:38169-38798 38169-38798 98.6% 175.49 120.75 149.73 99.82 66.01 35.42 148.12 124.77 50.71 0.55 0.51 0.21 -1.30 -1.40 Frag>80[5688,5689]
YPL266W DIM1 "Essential 18S rRNA dimethylase (dimethyladenosine transferase), responsible for conserved m6(2)Am6(2)A dimethylation in 3'-terminal loop of 18S rRNA, part of 90S and 40S pre-particles in nucleolus, involved in pre-ribosomal RNA processing" Verified chr16:39121-40077 39121-40077 98.6% 330.70 160.05 261.80 187.61 29.68 6.36 245.37 224.71 18.02 0.91 0.91 0.07 -3.64 -3.54 Matched[5690]
YPL265W DIP5 "Dicarboxylic amino acid permease, mediates high-affinity and high-capacity transport of L-glutamate and L-aspartate; also a transporter for Gln, Asn, Ser, Ala, and Gly" Verified chr16:41043-42869 41043-42869 99.0% 311.18 665.47 464.28 380.82 665.47 453.23 488.32 422.55 559.35 1.80 1.72 2.32 0.40 0.89 Matched[5692]
YPL264C Putative membrane protein of unknown function; physically interacts with Hsp82p; YPL264C is not an essential gene Uncharacterized chr16:43283-44344 43283-44344 98.8% 36.22 64.81 33.36 27.64 80.06 74.34 50.52 30.50 77.20 0.19 0.12 0.32 1.34 1.44 Matched[5693]
YPL263C KEL3 Cytoplasmic protein of unknown function Verified chr16:44551-46506 44551-46506 99.2% 285.57 214.95 217.53 214.44 76.29 76.29 250.26 215.98 76.29 0.92 0.88 0.32 -1.50 -0.83 Matched[5694]
YPL262W FUM1 "Fumarase, converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial localization determined by the N-terminal mitochondrial targeting sequence and protein conformation; phosphorylated in mitochondria" Verified chr16:47336-48802 47336-48802 98.8% 494.11 514.81 452.70 505.15 601.76 581.75 504.46 478.92 591.75 1.86 1.94 2.45 0.31 0.86 Matched[5696]
YPL260W Putative substrate of cAMP-dependent protein kinase (PKA); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YPL260W is not an essential gene Uncharacterized chr16:49303-50958 49303-50958 98.7% 346.75 339.41 361.43 345.53 625.62 522.27 343.08 353.48 573.95 1.27 1.43 2.38 0.70 0.81 Matched[5697]
YPL261C Dubious open reading frame unlikely to encode a protein; partially overlaps the uncharacterized ORF YPL260W Dubious chr16:48996-49304 48996-49304 98.8% 68.80 65.52 78.62 91.73 81.90 127.76 67.16 85.18 104.83 0.25 0.35 0.43 0.30 -0.02
YPL259C APM1 Mu1-like medium subunit of the clathrin-associated protein complex (AP-1); binds clathrin; involved in clathrin-dependent Golgi protein sorting Verified chr16:51244-52671 51244-52671 99.2% 152.45 160.22 158.10 148.22 148.22 114.34 156.33 153.16 131.28 0.58 0.62 0.54 -0.22 0.41 Matched[5698]
YPL258C THI21 "Hydroxymethylpyrimidine phosphate kinase, involved in the last steps in thiamine biosynthesis; member of a gene family with THI20 and THI22; functionally redundant with Thi20p" Verified chr16:53498-55153 53498-55153 97.2% 49.69 66.46 36.03 22.36 19.88 17.39 58.08 29.19 18.63 0.21 0.12 0.08 -0.65 -0.76 Covered[5699]
YPL257W Putative protein of unknown function;; homozygous diploid deletion strain exhibits low budding index; physically interacts with Hsp82p; YPL257W is not an essential gene Uncharacterized chr16:63279-63860 63279-63860 99.0% 29.49 50.31 34.70 26.02 76.34 34.70 39.90 30.36 55.52 0.15 0.12 0.23 0.87 0.85 Covered[5700]
YPL256C CLN2 "G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)" Verified chr16:64977-66614 64977-66614 98.9% 476.56 350.63 328.40 232.72 48.15 17.90 413.59 280.56 33.03 1.53 1.14 0.14 -3.09 -2.50 Matched[5701]
YPL255W BBP1 "Protein required for the spindle pole body (SPB) duplication, localized at the central plaque periphery; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p" Verified chr16:67725-68882 67725-68882 98.5% 112.24 94.70 125.39 92.95 57.87 26.31 103.47 109.17 42.09 0.38 0.44 0.17 -1.38 -0.48 Matched[5702]
YPL254W HFI1 "Adaptor protein required for structural integrity of the SAGA complex, a histone acetyltransferase-coactivator complex that is involved in global regulation of gene expression through acetylation and transcription functions" Verified chr16:69485-70951 69485-70951 98.7% 118.78 116.71 125.69 102.21 93.92 75.96 117.75 113.95 84.94 0.43 0.46 0.35 -0.42 -0.08 Covered/w/another[5703]
YPL253C VIK1 "Protein that forms a complex with Kar3p at the spindle pole body, possible regulator of Kar3p function in microtubule-mediated processes; required for sister chromatid cohesion; has similarity to Cik1p" Verified chr16:71063-73006 71063-73006 99.2% 86.07 77.78 79.85 54.96 60.15 44.07 81.92 67.41 52.11 0.30 0.27 0.22 -0.37 0.05 Covered/w/another[5703]
YPL251W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps 5' end of the verified, essential gene YAH1/YPL252C" Dubious chr16:73625-73927 73625-73927 98.3% 312.34 335.85 295.55 251.89 134.34 50.38 324.10 273.72 92.36 1.20 1.11 0.38 -1.57 -0.44 Matched[5704]
YPL252C YAH1 Ferredoxin of the mitochondrial matrix required for formation of cellular iron-sulfur proteins; involved in heme A biosynthesis; homologous to human adrenodoxin Verified chr16:73363-73881 73363-73881 98.2% 366.91 347.29 362.98 288.42 131.46 45.13 357.10 325.70 88.29 1.32 1.32 0.37 -1.88 -1.63 Matched[5704]
YPL250C ICY2 Protein of unknown function; mobilized into polysomes upon a shift from a fermentable to nonfermentable carbon source; potential Cdc28p substrate Verified chr16:74309-74719 74309-74719 98.4% 86.53 215.08 61.80 42.03 889.99 1075.40 150.80 51.92 982.69 0.56 0.21 4.07 4.24 3.77 Matched[5705]
YPL250W-A Identified by fungal homology and RT-PCR Dubious chr16:75702-75989 75702-75989 73.5% 10016.53 8358.91 9157.02 7631.64 2984.65 3178.28 9187.72 8394.33 3081.46 33.92 34.07 12.77 -1.45 NaN Matched[5707]
YPL249C-A RPL36B "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl36Ap and has similarity to rat L36 ribosomal protein; binds to 5.8 S rRNA" Verified chr16:75699-76239 75699-75985,76224-76239 74.8% 9481.81 7925.03 8657.11 7223.81 2835.72 2994.49 8703.42 7940.46 2915.10 32.13 32.23 12.08 -1.45 -2.53 Frag>80[5706,5707,5708]
YPL249C GYP5 "GTPase-activating protein (GAP) for yeast Rab family members, involved in ER to Golgi trafficking; exhibits GAP activity toward Ypt1p that is stimulated by Gyl1p, also acts on Sec4p; interacts with Gyl1p, Rvs161p and Rvs167p" Verified chr16:76669-79353 76669-79353 99.2% 94.57 90.44 88.94 80.68 114.46 132.47 92.50 84.81 123.46 0.34 0.34 0.51 0.54 1.15 Matched[5709]
YPL248C GAL4 DNA-binding transcription factor required for the activation of the GAL genes in response to galactose; repressed by Gal80p and activated by Gal3p Verified chr16:79711-82356 79711-82356 98.8% 43.98 45.13 36.71 30.98 39.77 21.03 44.55 33.84 30.40 0.16 0.14 0.13 -0.15 -0.62 Matched[5710]
YPL247C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; similar to the petunia WD repeat protein an11; YPL247C is not an essential gene Uncharacterized chr16:82625-84196 82625-84196 98.7% 84.40 120.48 124.99 119.19 907.14 875.57 102.44 122.09 891.36 0.38 0.50 3.69 2.87 2.79 Frag>80[5711,5712]
YPL246C RBD2 "Possible rhomboid protease, has similarity to eukaryotic rhomboid proteases including Pcp1p" Verified chr16:84509-85297 84509-85297 98.6% 604.21 641.49 663.35 556.64 290.54 210.83 622.85 610.00 250.68 2.30 2.48 1.04 -1.28 -1.01 Matched[5713]
YPL245W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the cytoplasm Uncharacterized chr16:85586-86950 85586-86950 98.6% 213.22 144.87 149.33 105.50 76.52 52.75 179.05 127.41 64.64 0.66 0.52 0.27 -0.98 -1.19 Matched[5714]
YPL244C HUT1 "Protein with a role in UDP-galactose transport to the Golgi lumen, has similarity to human UDP-galactose transporter UGTrel1, exhibits a genetic interaction with S. cerevisiae ERO1" Verified chr16:87014-88033 87014-88033 99.1% 245.28 228.47 234.40 216.60 144.40 106.82 236.87 225.50 125.61 0.87 0.92 0.52 -0.84 -0.97 Matched[5715]
YPL243W SRP68 Core component of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex that functions in targeting nascent secretory proteins to the endoplasmic reticulum (ER) membrane Verified chr16:88517-90316 88517-90316 98.8% 386.30 317.14 327.26 336.82 237.85 125.95 351.72 332.04 181.90 1.30 1.35 0.75 -0.87 -0.96 Matched[5716]
YPL242C IQG1 "Essential protein required for determination of budding pattern, promotes localization of axial markers Bud4p and Cdc12p and functionally interacts with Sec3p, localizes to the contractile ring during anaphase, member of the IQGAP family" Verified chr16:90622-95109 90622-95109 99.2% 107.80 103.99 90.96 82.65 75.69 60.41 105.89 86.80 68.05 0.39 0.35 0.28 -0.35 0.19 Matched[5717]
YPL241C CIN2 Tubulin folding factor C (putative) involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl Verified chr16:95372-96258 95372-96153,96234-96258 99.1% 127.49 157.49 136.24 122.49 43.75 28.75 142.49 129.37 36.25 0.53 0.53 0.15 -1.84 -1.37 Matched[5718]
YPL240C HSP82 "Cytoplasmic chaperone (Hsp90 family) required for pheromone signaling and negative regulation of Hsf1p; docks with the mitochondrial import receptor Tom70p for preprotein delivery; interacts with co-chaperones Cns1p, Cpr6p, Cpr7p, and Sti1p" Verified chr16:96496-98625 96496-98625 61.5% 569.45 842.72 620.59 805.32 24226.71 19661.21 706.08 712.95 21943.96 2.61 2.89 90.92 4.94 3.89 Matched[5719]
YPL239W YAR1 "Cytoplasmic ankyrin-repeat containing protein of unknown function, proposed to link the processes of 40S ribosomal subunit biogenesis and adaptation to osmotic and oxidative stress; expression repressed by heat shock" Verified chr16:99484-100086 99484-100086 98.2% 459.30 270.18 275.24 243.16 1732.50 1053.68 364.74 259.20 1393.09 1.35 1.05 5.77 2.43 1.99 Matched[5721]
YPL237W SUI3 "Beta subunit of the translation initiation factor eIF2, involved in the identification of the start codon; proposed to be involved in mRNA binding" Verified chr16:100496-101353 100496-101353 98.4% 2108.59 1614.61 1741.36 1648.96 709.58 461.99 1861.60 1695.16 585.78 6.87 6.88 2.43 -1.53 -1.54 Frag>80[5722,5723]
YPL238C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps 5' end of the verified essential gene SUI3/YPL237W" Dubious chr16:100474-100863 100474-100863 97.9% 1877.58 1542.39 1576.43 1482.16 665.14 395.42 1709.98 1529.30 530.28 6.31 6.21 2.20 -1.53 -0.04 Frag>80[5722,5723]
YPL236C Putative protein kinase that exhibits Akr1p-dependent palmitoylation Uncharacterized chr16:101608-102702 101608-102702 99.0% 81.16 92.23 81.16 75.63 126.35 90.38 86.69 78.39 108.37 0.32 0.32 0.45 0.47 0.52 Matched[5724]
YPL235W RVB2 Essential protein involved in transcription regulation; component of chromatin remodeling complexes; required for assembly and function of the INO80 complex; member of the RUVB-like protein family Verified chr16:103232-104647 103232-104647 98.6% 373.97 300.18 332.42 361.79 246.45 262.93 337.07 347.10 254.69 1.24 1.41 1.06 -0.45 -0.02 Frag>80[5725,5726]
YPL234C TFP3 "Vacuolar ATPase V0 domain subunit c', involved in proton transport activity; hydrophobic integral membrane protein (proteolipid) containing four transmembrane segments; N and C termini are in the vacuolar lumen" Verified chr16:104946-105440 104946-105440 98.8% 2683.03 2824.13 2255.62 2319.02 2128.83 1588.96 2753.58 2287.32 1858.90 10.16 9.28 7.70 -0.30 -0.34 Matched[5727]
YPL233W NSL1 Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; required for accurate chromosome segregation Verified chr16:106172-106822 106172-106822 98.3% 78.17 89.11 57.84 59.41 48.46 42.21 83.64 58.62 45.34 0.31 0.24 0.19 -0.37 -0.13 Matched[5728]
YPL232W SSO1 Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane and in vesicle fusion during sporulation; forms a complex with Sec9p that binds v-SNARE Snc2p; syntaxin homolog; functionally redundant with Sso2p Verified chr16:107275-108147 107275-108147 98.3% 409.11 413.77 452.24 338.01 486.04 392.79 411.44 395.12 439.42 1.52 1.60 1.82 0.15 0.57 Matched[5729]
YPL231W FAS2 "Alpha subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains beta-ketoacyl reductase and beta-ketoacyl synthase activities; phosphorylated" Verified chr16:108652-114315 108652-114315 98.7% 775.60 1246.22 695.47 716.22 191.93 308.20 1010.91 705.84 250.07 3.73 2.87 1.04 -1.50 -0.31 Frag>80[5730,5731]
YPL230W Putative protein of unknown function Uncharacterized chr16:115218-116487 115218-115219,115294-116487 99.0% 48.99 128.39 79.40 72.64 1049.06 576.05 88.69 76.02 812.56 0.33 0.31 3.37 3.42 2.50 Matched[5732]
YPL229W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YPL229W is not an essential gene Uncharacterized chr16:117067-117687 117067-117687 98.4% 68.75 72.03 75.30 73.66 80.21 68.75 70.39 74.48 74.48 0.26 0.30 0.31 0.00 0.09 Matched[5734]
YPL228W CET1 "Beta (RNA 5'-triphosphatase) subunit of the mRNA capping enzyme, a heterodimer (the other subunit is CEG1, a guanylyltransferase) involved in adding the 5' cap to mRNA; the mammalian enzyme is a single bifunctional polypeptide" Verified chr16:118382-120031 118382-120031 98.6% 148.68 124.10 149.29 159.12 169.57 125.95 136.39 154.21 147.76 0.50 0.63 0.61 -0.06 0.20 Matched[5735]
YPL227C ALG5 "UDP-glucose:dolichyl-phosphate glucosyltransferase, involved in asparagine-linked glycosylation in the endoplasmic reticulum" Verified chr16:120163-121167 120163-121167 99.3% 274.66 257.62 278.67 254.62 126.31 79.19 266.14 266.64 102.75 0.98 1.08 0.43 -1.38 -1.44 Matched[5736]
YPL226W NEW1 "ATP binding cassette family member; Asn/Gln-rich rich region supports [NU+] prion formation, susceptibility to [PSI+] prion induction and aggregation of a fragment of the human Machado-Joseph Disease protein" Verified chr16:121767-125357 121767-125357 98.8% 527.60 422.75 393.16 352.29 39.18 38.33 475.17 372.73 38.75 1.75 1.51 0.16 -3.27 -2.52 Matched[5737]
YPL225W "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" Verified chr16:126006-126446 126006-126446 98.7% 937.75 1038.88 1031.99 896.38 3031.60 1728.40 988.32 964.18 2380.00 3.65 3.91 9.86 1.30 0.45 Matched[5738]
YPL224C MMT2 Putative metal transporter involved in mitochondrial iron accumulation; closely related to Mmt1p Verified chr16:126738-128087 126738-128087 99.0% 117.49 134.70 120.48 145.92 246.20 213.27 126.09 133.20 229.73 0.47 0.54 0.95 0.79 0.90 Matched[5739]
YPL223C GRE1 "Hydrophilin of unknown function; stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway" Verified chr16:128631-129137 128631-129137 98.9% 23.92 31.90 25.92 29.91 151.52 89.72 27.91 27.91 120.62 0.10 0.11 0.50 2.11 1.16 Covered/w/another[5740]
YPL222W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr16:130161-132227 130161-132227 98.5% 30.46 58.47 38.33 46.19 204.41 207.35 44.47 42.26 205.88 0.16 0.17 0.85 2.28 2.51 Covered/w/another[5740]
YPL222C-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr16:131869-132114 131869-132114 98.3% 33.07 86.82 62.02 74.42 376.23 260.47 59.95 68.22 318.35 0.22 0.28 1.32 2.22 NaN Covered/w/another[5740]
YPL221W FLC1 Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance Verified chr16:133042-135423 133042-135423 98.8% 181.95 195.13 162.39 133.91 154.31 169.19 188.54 148.15 161.75 0.70 0.60 0.67 0.13 0.73 Matched[5741]
YPL220W RPL1A "N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl1Bp and has similarity to E. coli L1 and rat L10a ribosomal proteins; rpl1a rpl1b double null mutation is lethal" Verified chr16:135789-136442 135789-136442 6.6% 5114.75 3286.40 4235.29 3610.41 810.03 995.18 4200.58 3922.85 902.60 15.51 15.92 3.74 -2.12 -1.94 Frag<80[5742,5743,5744,5745]
YPL219W PCL8 "Cyclin, interacts with Pho85p cyclin-dependent kinase (Cdk) to phosphorylate and regulate glycogen synthase, also activates Pho85p for Glc8p phosphorylation" Verified chr16:136749-138227 136749-138227 98.8% 63.67 99.96 76.68 82.84 138.30 122.55 81.81 79.76 130.42 0.30 0.32 0.54 0.71 0.80 Frag>80[5744,5745,5746,5747]
YPL218W SAR1 "GTPase, GTP-binding protein of the ARF family, component of COPII coat of vesicles; required for transport vesicle formation during ER to Golgi protein transport" Verified chr16:138697-139408 138697-138724,138864-139408 99.0% 1673.60 1521.93 1504.30 1361.45 1636.56 1015.80 1597.77 1432.88 1326.18 5.90 5.82 5.49 -0.11 -0.14 Matched[5748]
YPL217C BMS1 "Essential conserved nucleolar GTP-binding protein required for synthesis of 40S ribosomal subunits and for processing of the 35S pre-rRNA at sites A0, A1, and A2; interacts with Rcl1p, has similarity to Tsr1p" Verified chr16:139619-143170 139619-143170 99.3% 259.70 147.43 159.05 131.55 22.40 17.01 203.57 145.30 19.70 0.75 0.59 0.08 -2.88 -2.17 Matched[5749]
YPL216W Putative protein of unknown function; YPL216W is not an essential gene Uncharacterized chr16:143820-147128 143820-147128 98.7% 43.77 37.95 34.59 34.28 41.01 23.57 40.86 34.43 32.29 0.15 0.14 0.13 -0.09 -0.10 Matched[5750]
YPL215W CBP3 Mitochondrial protein required for assembly of ubiquinol cytochrome-c reductase complex (cytochrome bc1 complex); interacts with Cbp4p and function is partially redundant with that of Cbp4p Verified chr16:147415-148422 147415-148422 98.7% 253.26 271.35 282.40 250.24 277.38 184.92 262.30 266.32 231.15 0.97 1.08 0.96 -0.20 -0.06 Matched[5751]
YPL214C THI6 "Bifunctional enzyme with thiamine-phosphate pyrophosphorylase and 4-methyl-5-beta-hydroxyethylthiazole kinase activities, required for thiamine biosynthesis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern" Verified chr16:148568-150190 148568-150190 98.9% 120.19 148.84 118.95 96.53 137.63 98.40 134.52 107.74 118.01 0.50 0.44 0.49 0.13 0.08 Matched[5752]
YPL213W LEA1 Component of U2 snRNP; disruption causes reduced U2 snRNP levels; physically interacts with Msl1p; invovled in telomere maintenance; putative homolog of human U2A' snRNP protein Verified chr16:150613-151329 150613-151329 98.6% 89.15 108.96 79.25 75.00 96.23 76.42 99.06 77.12 86.32 0.37 0.31 0.36 0.16 -0.13 Matched[5753]
YPL212C PUS1 "tRNA:pseudouridine synthase, introduces pseudouridines at positions 26-28, 34-36, 65, and 67 of tRNA; nuclear protein that appears to be involved in tRNA export; also acts on U2 snRNA" Verified chr16:151514-153148 151514-153148 99.2% 333.53 303.94 224.41 225.64 19.11 9.86 318.73 225.03 14.49 1.18 0.91 0.06 -3.96 -3.16 Matched[5754]
YPL211W NIP7 "Nucleolar protein required for 60S ribosome subunit biogenesis, constituent of 66S pre-ribosomal particles; physically interacts with Nop8p and the exosome subunit Rrp43p" Verified chr16:153494-154039 153494-154039 98.7% 602.88 272.69 430.36 341.32 29.68 5.57 437.78 385.84 17.62 1.62 1.57 0.07 -4.45 -4.24 Matched[5755]
YPL210C SRP72 Core component of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex that functions in targeting nascent secretory proteins to the endoplasmic reticulum (ER) membrane Verified chr16:154289-156211 154289-156211 99.3% 385.91 338.78 342.45 325.69 242.43 176.46 362.34 334.07 209.45 1.34 1.36 0.87 -0.67 -0.49 Matched[5756]
YPL209C IPL1 "Aurora kinase involved in regulating kinetochore-microtubule attachments; helps maintain condensed chromosomes during anaphase and early telophase; associates with Sli15p, which promotes Ipl1p association with mitotic spindle" Verified chr16:156489-157592 156489-157592 99.3% 41.97 31.93 41.97 31.02 38.32 20.07 36.95 36.49 29.20 0.14 0.15 0.12 -0.32 0.48 Matched[5757]
YPL208W RKM1 "SET-domain lysine-N-methyltransferase, catalyzes the formation of dimethyllysine residues on the large ribsomal subunit protein L23a (RPL23A and RPL23B)" Verified chr16:157841-159592 157841-159592 98.9% 155.20 182.89 139.62 140.20 166.16 113.08 169.04 139.91 139.62 0.62 0.57 0.58 -0.00 -0.06 Matched[5758]
YPL207W TYW1 "Protein required for the synthesis of wybutosine, a modified guanosine found at the 3'-position adjacent to the anticodon of phenylalanine tRNA which supports reading frame maintenance by stabilizing codon-anticodon interactions" Verified chr16:159908-162340 159908-162340 98.5% 208.30 166.56 170.73 144.85 27.13 16.70 187.43 157.79 21.92 0.69 0.64 0.09 -2.85 -2.15 Matched[5759]
YPL206C Protein that plays a role in metabolism of glycerophosphocholine to phosphatidylcholine; contains glycerophosphodiester phosphodiesterase motifs Uncharacterized chr16:162631-163596 162631-163596 99.2% 306.76 364.14 343.27 339.10 622.90 405.88 335.45 341.19 514.39 1.24 1.38 2.13 0.59 0.75 Matched[5760]
YPL205C Hypothetical protein; deletion of locus affects telomere length Dubious chr16:163921-164265 163921-164265 98.2% 185.89 185.89 159.33 165.23 138.68 168.18 185.89 162.28 153.43 0.69 0.66 0.64 -0.08 -0.05 Covered/w/another[5761]
YPL204W HRR25 "Protein kinase involved in regulating diverse events including vesicular trafficking, DNA repair, and chromosome segregation; binds the CTD of RNA pol II; homolog of mammalian casein kinase 1delta (CK1delta)" Verified chr16:164275-165759 164275-165759 98.7% 530.33 614.96 557.63 520.77 494.16 387.00 572.65 539.20 440.58 2.11 2.19 1.83 -0.29 -0.17 Matched[5761]
YPL203W TPK2 cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk1p and Tpk3p Verified chr16:166255-167397 166255-167397 98.8% 177.10 200.12 243.51 266.53 620.72 495.87 188.61 255.02 558.29 0.70 1.04 2.31 1.13 1.59 Matched[5762]
YPL202C AFT2 Iron-regulated transcriptional activator; activates genes involved in intracellular iron use and required for iron homeostasis and resistance to oxidative stress; similar to Aft1p Verified chr16:168087-169337 168087-169337 99.1% 143.53 158.05 115.31 89.51 104.02 91.93 150.79 102.41 97.97 0.56 0.42 0.41 -0.06 0.62 Matched[5763]
YPL201C YIG1 Protein that interacts with glycerol 3-phosphatase and plays a role in anaerobic glycerol production; localizes to the nucleus and cytosol Verified chr16:169769-171154 169769-171154 99.2% 19.64 19.64 7.28 5.82 4.37 21.10 19.64 6.55 12.73 0.07 0.03 0.05 0.96 -0.35 Frag<80[5764]
YPL200W CSM4 Protein required for accurate chromosome segregation during meiosis Verified chr16:171483-171953 171483-171953 98.8% 12.89 8.59 8.59 4.30 2.15 4.30 10.74 6.44 3.22 0.04 0.03 0.01 -1.00 -0.19
YPL199C Hypothetical protein Uncharacterized chr16:172032-172754 172032-172754 99.4% 384.04 417.44 361.78 269.94 198.98 119.67 400.74 315.86 159.32 1.48 1.28 0.66 -0.99 -0.81 Frag>80[5765,5766]
YPL198W RPL7B "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl7Ap and has similarity to E. coli L30 and rat L7 ribosomal proteins; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2)" Verified chr16:173151-174701 173151-173161,173571-173664,174072-174701 26.8% 1120.64 1014.16 856.96 431.02 187.62 35.50 1067.40 643.99 111.56 3.94 2.61 0.46 -2.53 -2.06 Frag<80[5766,5767,5768]
YPL197C "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the ribosomal gene RPB7B" Dubious chr16:174342-174755 174342-174755 30.6% 1546.35 1317.55 1049.31 568.05 205.13 15.78 1431.95 808.68 110.45 5.29 3.28 0.46 -2.87 -0.09 Frag<80[5768]
YPL196W OXR1 "Protein of unknown function required for normal levels of resistance to oxidative damage, null mutants are sensitive to hydrogen peroxide; member of a conserved family of proteins found in eukaryotes but not in prokaryotes" Verified chr16:175042-175863 175042-175863 98.6% 143.12 177.67 151.76 156.69 563.85 303.52 160.39 154.23 433.68 0.59 0.63 1.80 1.49 1.39 Matched[5769]
YPL195W APL5 "Delta adaptin-like subunit of the clathrin associated protein complex (AP-3); functions in transport of alkaline phosphatase to the vacuole via the alternate pathway, suppressor of loss of casein kinase 1 function" Verified chr16:176222-179020 176222-179020 98.8% 289.92 288.48 263.53 262.81 301.13 258.11 289.20 263.17 279.62 1.07 1.07 1.16 0.09 0.43 Matched[5770]
YPL194W DDC1 "DNA damage checkpoint protein, part of a PCNA-like complex required for DNA damage response, required for pachytene checkpoint to inhibit cell cycle in response to unrepaired recombination intermediates; potential Cdc28p substrate" Verified chr16:179276-181114 179276-181114 98.6% 39.70 46.31 39.15 35.84 41.90 35.29 43.00 37.49 38.59 0.16 0.15 0.16 0.04 0.45 Covered/w/another[5771]
YPL193W RSA1 Protein involved in the assembly of 60S ribosomal subunits; functionally interacts with Dbp6p; functions in a late nucleoplasmic step of the assembly Verified chr16:181402-182547 181402-182547 98.7% 141.47 102.57 102.57 106.99 121.14 85.77 122.02 104.78 103.45 0.45 0.43 0.43 -0.02 -0.07 Covered/w/another[5771]
YPL192C PRM3 Pheromone-regulated protein required for karyogamy; localizes to the inner membrane of the nuclear envelope Verified chr16:182654-183055 182654-183055 99.2% 115.34 50.15 65.19 35.10 47.64 27.58 82.74 50.15 37.61 0.31 0.20 0.16 -0.42 -1.39 Covered/w/another[5771]
YPL191C Putative protein of unknown function; diploid deletion strain exhibits high budding index; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr16:183596-184678 183596-184678 99.3% 55.81 74.42 45.58 40.93 126.51 63.25 65.11 43.25 94.88 0.24 0.18 0.39 1.13 0.85 Covered/w/another[5771]
YPL190C NAB3 Single stranded RNA binding protein; acidic ribonucleoprotein; required for termination of non-poly(A) transcripts and efficient splicing; interacts with Nrd1p Verified chr16:185316-187724 185316-187724 97.2% 290.48 264.43 256.74 209.32 242.64 291.77 277.46 233.03 267.20 1.02 0.95 1.11 0.20 0.70 Frag>80[5772,5773]
YPL189C-A Putative protein of unknown function; identified by homology to Ashbya gossypii Uncharacterized chr16:188306-188512 188306-188512 98.4% 225.77 265.03 319.02 260.12 603.68 441.72 245.40 289.57 522.70 0.91 1.18 2.17 0.85 NaN Matched[5774]
YPL189W GUP2 Probable membrane protein with a possible role in proton symport of glycerol; member of the MBOAT family of putative membrane-bound O-acyltransferases; Gup1p homolog Verified chr16:189153-190982 189153-190982 98.9% 17.12 19.88 14.36 13.81 7.73 21.54 18.50 14.08 14.64 0.07 0.06 0.06 0.06 -0.18
YPL188W POS5 "Mitochondrial NADH kinase, phosphorylates NADH; also phosphorylates NAD(+) with lower specificity; required for the response to oxidative stress" Verified chr16:191405-192649 191405-192649 98.8% 81.26 115.38 104.01 88.57 159.26 135.70 98.32 96.29 147.48 0.36 0.39 0.61 0.62 1.09 Matched[5775]
YPL187W MF(ALPHA)1 "Mating pheromone alpha-factor, made by alpha cells; interacts with mating type a cells to induce cell cycle arrest and other responses leading to mating; also encoded by MF(ALPHA)2, although MF(ALPHA)1 produces most alpha-factor" Verified chr16:193647-194144 193647-194144 72.7% 5.52 11.05 2.76 2.76 0.00 8.29 8.29 2.76 4.14 0.03 0.01 0.02 0.58 -0.05
YPL185W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene UIP4/YPL186C" Dubious chr16:195252-195647 195252-195647 99.0% 25.50 50.99 40.79 43.34 446.19 334.01 38.24 42.07 390.10 0.14 0.17 1.62 3.21 0.12 Frag>80[5777,5778]
YPL186C UIP4 "Protein that interacts with Ulp1p, a Ubl (ubiquitin-like protein)-specific protease for Smt3p protein conjugates; detected in a phosphorylated state in the mitochondrial outer membrane; also detected in ER and nuclear envelope" Verified chr16:194511-195425 194511-195425 99.3% 38.53 117.78 72.65 86.96 1375.96 887.22 78.15 79.81 1131.59 0.29 0.32 4.69 3.83 3.56 Matched[5777]
YPL184C Putative RNA binding protein Uncharacterized chr16:195949-197787 195949-197787 98.6% 424.29 433.11 370.77 387.87 200.28 236.70 428.70 379.32 218.49 1.58 1.54 0.91 -0.80 0.14 Covered[5779]
YPL183W-A "Homolog of the prokaryotic ribosomal protein L36, likely to be a mitochondrial ribosomal protein coded in the nuclear genome" Uncharacterized chr16:199094-199375 199094-199375 98.8% 305.16 362.60 369.78 305.16 502.62 326.70 333.88 337.47 414.66 1.23 1.37 1.72 0.30 -0.07 Matched[5780]
YPL183C Cytoplasmic protein of unknown function Uncharacterized chr16:199494-202535 199494-202535 99.2% 140.89 97.79 81.55 65.30 15.25 8.29 119.34 73.43 11.77 0.44 0.30 0.05 -2.64 -2.31 Matched[5781]
YPL181W CTI6 Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p corepressor and recruiting the SAGA complex to the repressed promoter; contains a PHD finger domain Verified chr16:203420-204940 203420-204940 98.1% 155.48 172.91 143.42 125.32 141.41 107.90 164.20 134.37 124.65 0.61 0.55 0.52 -0.11 0.05 Matched[5782]
YPL182C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene CTI6/YPL181W" Dubious chr16:203305-203688 203305-203688 97.9% 101.03 79.76 95.71 58.49 47.86 58.49 90.40 77.10 53.17 0.33 0.31 0.22 -0.54 -0.08 Covered/w/another[5782]
YPL180W TCO89 "Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p), a complex that regulates growth in response to nutrient availability; cooperates with Ssd1p in the maintenance of cellular integrity; deletion strains are hypersensitive to rapamycin" Verified chr16:205247-207646 205247-207646 98.6% 89.54 108.13 88.70 79.41 92.08 87.85 98.83 84.05 89.97 0.36 0.34 0.37 0.10 0.64 Covered/w/another[5783]
YPL179W PPQ1 Putative protein serine/threonine phosphatase; null mutation enhances efficiency of translational suppressors Verified chr16:208156-209805 208156-209805 99.0% 314.68 312.84 310.39 225.91 222.23 174.48 313.76 268.15 198.36 1.16 1.09 0.82 -0.43 -0.02 Covered/w/another[5783]
YPL178W CBC2 "Small subunit of the heterodimeric cap binding complex that also contains Sto1p, component of the spliceosomal commitment complex; interacts with Npl3p, possibly to package mRNA for export from the nucleus; contains an RNA-binding motif" Verified chr16:212157-212783 212157-212783 98.7% 534.88 452.46 555.88 442.77 424.99 323.19 493.67 499.33 374.09 1.82 2.03 1.55 -0.42 -0.09 Matched[5785]
YPL177C CUP9 "Homeodomain-containing transcriptional repressor of PTR2, which encodes a major peptide transporter; imported peptides activate ubiquitin-dependent proteolysis, resulting in degradation of Cup9p and de-repression of PTR2 transcription" Verified chr16:213041-213961 213041-213961 98.9% 328.32 325.02 311.85 224.00 341.49 264.63 326.67 267.92 303.06 1.21 1.09 1.26 0.18 0.55 Matched[5786]
YPL176C TRE1 Plasma membrane protein that binds to Bsd2p and regulates ubiquitylation and vacuolar degradation of the metal transporter Smf1p; function is redundant with that of Tre2p; has similarity to transferrin receptors Verified chr16:216011-218362 216011-218362 99.0% 122.80 113.78 114.64 123.23 147.27 155.86 118.29 118.94 151.57 0.44 0.48 0.63 0.35 1.07 Matched[5790]
YPL175W SPT14 "UDP-GlcNAc-binding and catalytic subunit of the enzyme that mediates the first step in glycosylphosphatidylinositol (GPI) biosynthesis, mutations cause defects in transcription and in biogenesis of cell wall proteins" Verified chr16:218629-220087 218629-218645,218746-220087 98.8% 110.28 87.18 72.28 53.65 49.92 34.28 98.73 62.96 42.10 0.36 0.26 0.17 -0.58 -0.59 Covered/w/another[5791]
YPL174C NIP100 "Large subunit of the dynactin complex, which is involved in partitioning the mitotic spindle between mother and daughter cells; putative ortholog of mammalian p150(glued)" Verified chr16:220166-222772 220166-222772 99.4% 73.35 81.07 52.12 52.89 45.17 28.57 77.21 52.51 36.87 0.29 0.21 0.15 -0.51 -0.04 Covered/w/another[5791]
YPL173W MRPL40 Mitochondrial ribosomal protein of the large subunit Verified chr16:223142-224035 223142-224035 98.4% 184.11 187.52 219.34 218.20 222.75 159.11 185.81 218.77 190.93 0.69 0.89 0.79 -0.20 0.20 Covered/w/another[5792]
YPL172C COX10 "Heme A:farnesyltransferase, catalyzes the first step in the conversion of protoheme to the heme A prosthetic group required for cytochrome c oxidase activity; human ortholog is associated with mitochondrial disorders" Verified chr16:224352-225740 224352-225740 98.8% 106.35 91.06 109.27 87.41 135.49 82.31 98.70 98.34 108.90 0.36 0.40 0.45 0.15 0.20 Covered/w/another[5792]
YPL171C OYE3 "Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye2p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism" Verified chr16:226168-227370 226168-227370 98.8% 9.26 5.05 3.37 7.58 18.52 15.99 7.15 5.47 17.26 0.03 0.02 0.07 1.66 1.20
YPL170W DAP1 "Heme-binding protein involved in regulation of cytochrome P450 protein Erg11p; damage response protein, related to mammalian membrane progesterone receptors; mutations lead to defects in telomeres, mitochondria, and sterol synthesis" Verified chr16:228313-228771 228313-228771 98.2% 206.23 441.28 272.75 226.18 731.77 476.76 323.75 249.47 604.27 1.20 1.01 2.50 1.28 0.82 Frag>80[5793,5794]
YPL169C MEX67 "Poly(A)RNA binding protein involved in nuclear mRNA export, component of the nuclear pore; ortholog of human TAP" Verified chr16:229038-230837 229038-230837 99.0% 226.70 212.67 191.91 187.42 193.03 212.11 219.69 189.67 202.57 0.81 0.77 0.84 0.09 0.62 Matched[5795]
YPL168W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; expression may be cell cycle-regulated Uncharacterized chr16:231216-232508 231216-232508 98.7% 79.91 112.81 92.44 72.07 223.27 105.76 96.36 82.26 164.51 0.36 0.33 0.68 1.00 0.74 Matched[5796]
YPL167C REV3 "Catalytic subunit of DNA polymerase zeta, which is involved in DNA repair and translesion synthesis; required for mutagenesis induced by DNA damage" Verified chr16:232592-237106 232592-237106 99.2% 33.49 38.85 27.02 23.22 32.82 30.59 36.17 25.12 31.71 0.13 0.10 0.13 0.34 0.24 Frag<80[5797,5798]
YPL166W ATG29 Protein specifically required for autophagy; may function in autophagosome formation at the pre-autophagosomal structure in collaboration with other autophagy proteins Verified chr16:237337-237978 237337-237978 98.6% 56.86 86.86 77.39 58.44 208.48 165.83 71.86 67.91 187.15 0.27 0.28 0.78 1.46 1.68 Covered/w/another[5799]
YPL165C SET6 "Protein of unknown function; deletion heterozygote is sensitive to compounds that target ergosterol biosynthesis, may be involved in compound availability" Verified chr16:237955-239076 237955-239076 99.1% 107.88 140.24 142.04 97.99 411.73 234.63 124.06 120.01 323.18 0.46 0.49 1.34 1.43 0.09 Matched[5799]
YPL164C MLH3 Protein involved in DNA mismatch repair and crossing-over during meiotic recombination; forms a complex with Mlh1p; mammalian homolog is implicated mammalian microsatellite instability Verified chr16:239349-241496 239349-241496 99.1% 47.91 43.68 48.38 38.51 96.76 71.39 45.80 43.45 84.08 0.17 0.18 0.35 0.95 1.35 Matched[5800]
YPL163C SVS1 "Cell wall and vacuolar protein, required for wild-type resistance to vanadate" Verified chr16:241917-242699 241917-242699 98.5% 987.58 808.73 977.21 767.25 125.72 49.25 898.15 872.23 87.48 3.32 3.54 0.36 -3.32 -2.86 Matched[5801]
YPL162C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the membrane of vacuole with cell cycle-correlated morphology Uncharacterized chr16:243205-244026 243205-244026 98.9% 108.22 120.52 92.24 91.01 111.91 89.78 114.37 91.62 100.85 0.42 0.37 0.42 0.14 0.95 Covered/w/another[5802]
YPL161C BEM4 Protein involved in establishment of cell polarity and bud emergence; interacts with the Rho1p small GTP-binding protein and with the Rho-type GTPase Cdc42p; involved in maintenance of proper telomere length Verified chr16:244318-246219 244318-246219 99.3% 66.19 78.89 66.19 50.83 70.95 60.36 72.54 58.51 65.66 0.27 0.24 0.27 0.17 0.11 Covered/w/another[5802]
YPL160W CDC60 "Cytosolic leucyl tRNA synthetase, ligates leucine to the appropriate tRNA" Verified chr16:246989-250261 246989-250261 98.7% 836.93 790.21 752.47 719.36 156.25 172.03 813.57 735.91 164.14 3.00 2.99 0.68 -2.16 -1.49 Matched[5803]
YPL159C PET20 "Mitochondrial protein, required for respiratory growth under some conditions and for stability of the mitochondrial genome" Verified chr16:250906-251667 250906-251667 99.0% 169.63 176.26 144.45 143.13 250.47 206.74 172.94 143.79 228.60 0.64 0.58 0.95 0.67 0.89 Matched[5804]
YPL158C Hypothetical protein Uncharacterized chr16:252033-254309 252033-254309 97.6% 197.06 173.22 153.87 125.07 298.74 224.51 185.14 139.47 261.62 0.68 0.57 1.08 0.91 0.61 Matched[5805]
YPL157W TGS1 "Trimethyl guanosine synthase, conserved nucleolar methyl transferase responsible for conversion of the m(7)G cap structure of snRNAs and snoRNAs to m(2,2,7)G; also required for ribosome synthesis and nucleolar morphology" Verified chr16:254813-255760 254813-255760 98.5% 129.59 112.45 112.45 96.39 76.04 38.55 121.02 104.42 57.30 0.45 0.42 0.24 -0.87 -0.62 Covered/w/another[5806]
YPL156C PRM4 "Pheromone-regulated protein, predicted to have 1 transmembrane segment; transcriptionally regulated by Ste12p during mating and by Cat8p during the diauxic shift" Verified chr16:255912-256766 255912-256766 99.0% 141.72 115.74 126.37 102.75 138.18 94.48 128.73 114.56 116.33 0.48 0.47 0.48 0.02 0.22 Covered/w/another[5806]
YPL155C KIP2 "Kinesin-related motor protein involved in mitotic spindle positioning, stabilizes microtubules by targeting Bik1p to the plus end; Kip2p levels are controlled during the cell cycle" Verified chr16:257215-259335 257215-259335 99.1% 88.52 83.29 71.87 48.55 63.78 59.02 85.91 60.21 61.40 0.32 0.24 0.25 0.03 0.62 Covered/w/another[5806]
YPL154C PEP4 "Vacuolar aspartyl protease (proteinase A), required for the posttranslational precursor maturation of vacuolar proteinases; important for protein turnover after oxidative damage; synthesized as a zymogen, self-activates" Verified chr16:259713-260930 259713-260930 98.9% 2570.18 3285.78 2930.47 2747.01 5142.86 4574.20 2927.98 2838.74 4858.53 10.81 11.52 20.13 0.78 0.61 Frag>80[5807,5808]
YPL153C RAD53 "Protein kinase, required for cell-cycle arrest in response to DNA damage; activated by trans autophosphorylation when interacting with hyperphosphorylated Rad9p; also interacts with ARS1 and plays a role in initiation of DNA replication" Verified chr16:261726-264191 261726-264191 99.3% 51.47 49.84 50.66 37.18 29.41 25.74 50.66 43.92 27.57 0.19 0.18 0.11 -0.67 -0.46 Matched[5809]
YPL152W-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr16:264601-264699 264601-264699 99.0% 20.40 10.20 10.20 0.00 0.00 0.00 15.30 5.10 0.00 0.06 0.02 0.00 -Inf NaN
YPL152W RRD2 "Activator of the phosphotyrosyl phosphatase activity of PP2A,peptidyl-prolyl cis/trans-isomerase; regulates G1 phase progression, the osmoresponse, microtubule dynamics; subunit of the Tap42p-Pph21p-Rrd2p complex" Verified chr16:265027-266103 265027-266103 98.8% 95.82 90.19 83.61 51.67 207.62 140.92 93.01 67.64 174.27 0.34 0.27 0.72 1.37 1.54 Matched[5810]
YPL151C PRP46 Splicing factor that is found in the Cef1p subcomplex of the spliceosome Verified chr16:266179-267534 266179-267534 99.2% 94.46 103.38 90.74 81.81 197.84 160.65 98.92 86.27 179.24 0.37 0.35 0.74 1.05 1.25 Matched[5811]
YPL150W Putative protein kinase of unknown cellular role Uncharacterized chr16:268187-270892 268187-270892 98.7% 68.87 67.74 58.76 53.15 122.76 100.31 68.31 55.95 111.53 0.25 0.23 0.46 1.00 1.06 Matched[5812]
YPL149W ATG5 Conserved autophagy-related protein that undergoes conjugation with Atg12p and then associates with Atg16p to form a cytosolic complex essential for autophagosome formation Verified chr16:271309-272193 271309-272193 98.9% 99.42 92.57 66.28 41.14 65.14 27.43 96.00 53.71 46.28 0.35 0.22 0.19 -0.21 -0.45 Matched[5813]
YPL148C PPT2 "Phosphopantetheine:protein transferase (PPTase), activates mitochondrial acyl carrier protein (Acp1p) by phosphopantetheinylation" Verified chr16:272293-272814 272293-272814 98.9% 71.64 89.06 48.40 60.02 104.55 40.66 80.35 54.21 72.60 0.30 0.22 0.30 0.42 0.05 Covered/w/another[5813]
YPL147W PXA1 "Subunit of a heterodimeric peroxisomal ATP-binding cassette transporter complex (Pxa1p-Pxa2p), required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter and ALD-related proteins" Verified chr16:273254-275866 273254-275866 98.8% 13.94 18.20 22.46 17.82 61.97 36.02 16.07 20.14 49.00 0.06 0.08 0.20 1.28 1.22 Frag<80[5814]
YPL146C NOP53 Nucleolar protein; involved in biogenesis of the 60S subunit of the ribosome; interacts with rRNA processing factors Cbf5p and Nop2p; null mutant is viable but growth is severely impaired Verified chr16:276161-277528 276161-277528 99.0% 360.16 192.63 227.31 188.94 67.16 28.78 276.39 208.12 47.97 1.02 0.84 0.20 -2.12 -2.15 Matched[5815]
YPL145C KES1 "Member of the oxysterol binding protein family, which includes seven yeast homologs; involved in negative regulation of Sec14p-dependent Golgi complex secretory functions, peripheral membrane protein that localizes to the Golgi complex" Verified chr16:278394-279698 278394-279698 98.8% 773.69 704.70 721.75 700.05 425.61 364.36 739.20 710.90 394.99 2.73 2.89 1.64 -0.85 -0.23 Matched[5817]
YPL144W POC4 "Chaperone component involved in 20S proteasome assembly; forms a heterodimer with Irc25p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; null mutant is viable, exhibits shortened telomeres" Verified chr16:280479-280925 280479-280925 98.9% 153.86 162.91 158.39 156.12 74.67 36.20 158.39 157.25 55.44 0.58 0.64 0.23 -1.50 -1.35 Matched[5818]
YPL143W RPL33A "N-terminally acetylated ribosomal protein L37 of the large (60S) ribosomal subunit, nearly identical to Rpl33Bp and has similarity to rat L35a; rpl33a null mutant exhibits slow growth while rpl33a rpl33b double null mutant is inviable" Verified chr16:282121-282969 282121-282139,282665-282969 91.6% 10171.09 8579.86 9021.49 7983.14 2235.15 2029.50 9375.47 8502.32 2132.32 34.61 34.51 8.83 -2.00 -2.77 Frag>80[5820,5821]
YPL142C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified ORF RPL33A/YPL143W, a component of the large (60S) ribosomal subunit" Dubious chr16:282685-283002 282685-283002 94.9% 10354.37 8846.29 9313.63 8203.29 2313.49 2045.02 9600.33 8758.46 2179.26 35.44 35.55 9.03 -2.01 -1.62 Matched[5821]
YPL141C Putative protein kinase; similar to Kin4p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YPL141C is not an essential gene Uncharacterized chr16:283463-286060 283463-286060 98.9% 99.98 107.76 96.48 91.81 79.75 98.81 103.87 94.15 89.28 0.38 0.38 0.37 -0.08 0.73 Matched[5822]
YPL140C MKK2 "Mitogen-activated kinase kinase involved in protein kinase C signaling pathway that controls cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p" Verified chr16:287513-289033 287513-289033 99.1% 100.86 104.84 74.32 62.37 81.62 42.47 102.85 68.35 62.04 0.38 0.28 0.26 -0.14 0.43 Matched[5825]
YPL139C UME1 "Negative regulator of meiosis, required for repression of a subset of meiotic genes during vegetative growth, binding of histone deacetylase Rpd3p required for activity, contains a NEE box and a WD repeat motif; homologous with Wtm1p, Wtm2p" Verified chr16:289668-291050 289668-291050 99.2% 121.72 124.64 123.91 123.18 100.58 80.90 123.18 123.54 90.74 0.45 0.50 0.38 -0.45 0.03 Frag>80[5826,5827]
YPL138C SPP1 "Subunit of COMPASS (Set1C), a complex which methylates histone H3 on lysine 4 and is required in telomeric transcriptional silencing; PHD finger domain protein similar to human CGBP, an unmethylated CpG binding protein" Verified chr16:291365-292426 291365-292426 99.4% 103.23 114.60 89.97 76.71 101.34 48.30 108.91 83.34 74.82 0.40 0.34 0.31 -0.16 -0.17 Matched[5828]
YPL136W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene GIP3/YPL137C" Dubious chr16:296285-296653 296285-296653 98.8% 101.51 126.20 82.30 76.82 38.41 131.69 113.85 79.56 85.05 0.42 0.32 0.35 0.10 1.00 Covered/w/another[5829]
YPL137C GIP3 "Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; may interact with ribosomes, based on co-purification experiments" Verified chr16:292816-296646 292816-296646 98.9% 137.27 171.06 140.96 139.12 119.32 185.58 154.16 140.04 152.45 0.57 0.57 0.63 0.12 0.99 Covered/w/another[5829]
YPL135W ISU1 "Conserved protein of the mitochondrial matrix, performs a scaffolding function during assembly of iron-sulfur clusters, interacts physically and functionally with yeast frataxin (Yfh1p); isu1 isu2 double mutant is inviable" Verified chr16:297552-298049 297552-298049 98.3% 330.78 412.46 367.53 316.49 818.79 494.13 371.62 342.01 656.46 1.37 1.39 2.72 0.94 1.36 Matched[5830]
YPL135C-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr16:297677-297850 297677-297850 98.5% 279.95 431.59 361.60 309.11 734.87 408.26 355.77 335.36 571.57 1.31 1.36 2.37 0.77 NaN Matched[5830]
YPL134C ODC1 "Mitochondrial inner membrane transporter, exports 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol for lysine and glutamate biosynthesis and lysine catabolism; suppresses, in multicopy, an fmc1 null mutation" Verified chr16:298570-299502 298570-299502 98.9% 127.87 143.04 193.98 215.65 213.48 115.95 135.46 204.81 164.72 0.50 0.83 0.68 -0.31 -0.15 Covered/w/another[5831]
YPL133C RDS2 Zinc cluster transcriptional activator involved in conferring resistance to ketoconazole Verified chr16:299887-301227 299887-301227 99.1% 89.54 100.08 77.50 55.68 106.85 71.48 94.81 66.59 89.16 0.35 0.27 0.37 0.42 0.91 Covered/w/another[5831]
YPL132W COX11 Mitochondrial inner membrane protein required for delivery of copper to the Cox1p subunit of cytochrome c oxidase; association with mitochondrial ribosomes suggests that copper delivery may occur during translation of Cox1p Verified chr16:301715-302617 301715-302617 98.7% 201.90 210.87 188.44 170.49 281.53 154.79 206.38 179.46 218.16 0.76 0.73 0.90 0.28 0.14 Covered/w/another[5831]
YPL131W RPL5 Protein component of the large (60S) ribosomal subunit with similarity to E. coli L18 and rat L5 ribosomal proteins; binds 5S rRNA and is required for 60S subunit assembly Verified chr16:303120-304013 303120-304013 98.8% 9047.71 7472.18 7917.32 6451.65 1491.72 961.63 8259.95 7184.48 1226.67 30.49 29.16 5.08 -2.55 -2.83 Matched[5832]
YPL130W SPO19 "Meiosis-specific protein of unknown function, involved in completion of nuclear divisions; identified as a weak high-copy suppressor of the spo1-1 ts mutation; putative GPI-dependent cell-wall protein" Verified chr16:304386-305057 304386-305057 98.8% 3.01 3.01 0.00 1.51 0.00 6.02 3.01 0.75 3.01 0.01 0.00 0.01 2.00 -0.05
YPL129W TAF14 "Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes, involved in RNA polymerase II transcription initiation and in chromatin modification; contains a YEATS domain" Verified chr16:305297-306136 305297-305305,305411-306136 98.4% 519.70 469.94 454.73 398.06 328.96 219.77 494.82 426.40 274.36 1.83 1.73 1.14 -0.64 -0.64 Matched[5833]
YPL128C TBF1 Telobox-containing general regulatory factor; binds to TTAGGG repeats within subtelomeric anti-silencing regions (STARs) and possibly throughout the genome and mediates their insulating capacity by blocking silent chromatin propagation Verified chr16:306532-308220 306532-308220 98.7% 142.11 128.92 127.12 102.53 81.55 83.35 135.51 114.83 82.45 0.50 0.47 0.34 -0.48 -0.15 Matched[5834]
YPL127C HHO1 "Histone H1, a linker histone required for nucleosome packaging at restricted sites; suppresses DNA repair involving homologous recombination; not required for telomeric silencing, basal transcriptional repression, or efficient sporulation" Verified chr16:308827-309603 308827-309603 98.9% 726.33 670.35 712.01 718.52 636.51 471.20 698.34 715.26 553.86 2.58 2.90 2.29 -0.37 -0.19 Matched[5836]
YPL126W 1 "U3 snoRNP protein, component of the small (ribosomal) subunit (SSU) processosome containing U3 snoRNA; required for the biogenesis of18S rRNA" Verified chr16:310209-312899 310209-312899 99.0% 252.55 123.84 136.59 105.07 14.26 3.75 188.19 120.83 9.01 0.69 0.49 0.04 -3.75 -3.01 Matched[5837]
YPL125W KAP120 Karyopherin with a role in the assembly or export of 60S ribosomal subunits Verified chr16:313387-316485 313387-316485 99.0% 101.34 94.49 103.94 63.87 64.19 35.84 97.92 83.90 50.02 0.36 0.34 0.21 -0.75 -0.31 Matched[5838]
YPL124W SPC29 "Inner plaque spindle pole body (SPB) component, links the central plaque component Spc42p to the inner plaque component Spc110p; required for SPB duplication" Verified chr16:316754-317515 316754-317515 98.5% 65.30 49.31 50.64 61.30 89.28 58.63 57.30 55.97 73.96 0.21 0.23 0.31 0.40 0.66 Matched[5839]
YPL123C RNY1 RNAse; member of the T(2) family of endoribonucleases Verified chr16:317640-318944 317640-318944 99.3% 66.35 191.35 124.22 158.94 629.59 443.64 128.85 141.58 536.62 0.48 0.57 2.22 1.92 1.81 Matched[5840]
YPL122C TFB2 "Subunit of TFIIH and nucleotide excision repair factor 3 complexes, involved in transcription initiation, required for nucleotide excision repair, similar to 52 kDa subunit of human TFIIH" Verified chr16:319225-320766 319225-320766 99.2% 147.12 146.47 126.85 115.08 64.08 54.27 146.79 120.96 59.17 0.54 0.49 0.25 -1.03 -0.50 Matched[5841]
YPL121C MEI5 "Meiosis specific protein involved in DMC1-dependent meiotic recombination, forms heterodimer with Sae3p; proposed to be an assembly factor for Dmc1p" Verified chr16:320961-321629 320961-321629 99.6% 6.00 1.50 3.00 4.50 1.50 1.50 3.75 3.75 1.50 0.01 0.02 0.01 -1.32 0.92
YPL120W VPS30 "Protein that forms a membrane-associated complex with Apg14p that is essential for autophagy; involved in a retrieval step of the carboxypeptidase Y receptor, Vps10p, to the late Golgi from the endosome; involved in vacuolar protein sorting" Verified chr16:322070-323743 322070-323743 98.8% 64.09 76.18 66.51 69.53 129.99 101.57 70.13 68.02 115.78 0.26 0.28 0.48 0.77 1.04 Covered/w/another[5842]
YPL119C-A Putative protein of unknown function; identified by expression profiling and mass spectrometry Uncharacterized chr16:324023-324286 324023-324286 98.4% 65.44 69.29 65.44 38.49 196.31 96.23 67.36 51.96 146.27 0.25 0.21 0.61 1.49 NaN Covered/w/another[5842]
YPL119C DBP1 Putative ATP-dependent RNA helicase of the DEAD-box protein family; mutants show reduced stability of the 40S ribosomal subunit scanning through 5' untranslated regions of mRNAs Verified chr16:324410-326263 324410-326263 99.1% 36.47 39.19 40.28 38.64 80.55 66.95 37.83 39.46 73.75 0.14 0.16 0.31 0.90 1.21 Covered/w/another[5842]
YPL118W MRP51 Mitochondrial ribosomal protein of the small subunit; MRP51 exhibits genetic interactions with mutations in the COX2 and COX3 mRNA 5'-untranslated leader sequences Verified chr16:326627-327661 326627-327661 98.6% 452.72 454.68 476.24 449.78 692.80 480.16 453.70 463.01 586.48 1.67 1.88 2.43 0.34 0.01 Matched[5843]
YPL117C IDI1 "Isopentenyl diphosphate:dimethylallyl diphosphate isomerase (IPP isomerase), catalyzes an essential activation step in the isoprenoid biosynthetic pathway; required for viability" Verified chr16:327863-328729 327863-328729 99.2% 611.42 505.64 507.97 446.36 226.67 172.03 558.53 477.16 199.35 2.06 1.94 0.83 -1.26 -1.10 Matched[5844]
YPL116W HOS3 "Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) with specificity in vitro for histones H3, H4, H2A, and H2B; similar to Hda1p, Rpd3p, Hos1p, and Hos2p; deletion results in increased histone acetylation at rDNA repeats" Verified chr16:329605-331698 329605-331698 98.7% 135.45 132.55 150.45 139.32 205.12 191.09 134.00 144.89 198.10 0.49 0.59 0.82 0.45 0.71 Covered/w/another[5845]
YPL115C BEM3 "Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton organization; targets the essential Rho-GTPase Cdc42p, which controls establishment and maintenance of cell polarity, including bud-site assembly" Verified chr16:332099-335485 332099-335485 99.0% 131.22 120.79 104.08 96.63 82.61 93.94 126.00 100.36 88.28 0.47 0.41 0.37 -0.19 0.42 Covered/w/another[5845]
YPL114W "Dubious open reading frame, unlikely to encode a functional protein; largely overlaps ORF YPL113C; diploid deletion in BY4743 strain background exhibits high budding index" Dubious chr16:335947-336366 335947-336366 99.0% 45.69 50.50 67.33 50.50 158.70 43.28 48.09 58.91 100.99 0.18 0.24 0.42 0.78 0.76 Covered/w/another[5845]
YPL113C Glyoxylate reductase; acts on glyoxylate and hydroxypyruvate substrates; YPL113C is not an essential gene Uncharacterized chr16:335952-337142 335952-337142 99.2% 43.16 55.86 58.40 55.01 111.72 43.16 49.51 56.71 77.44 0.18 0.23 0.32 0.45 0.49 Covered/w/another[5845]
YPL112C PEX25 "Peripheral peroxisomal membrane peroxin required for the regulation of peroxisome size and maintenance, recruits GTPase Rho1p to peroxisomes, induced by oleate, interacts with homologous protein Pex27p" Verified chr16:337435-338619 337435-338619 99.2% 206.78 156.57 183.80 125.94 138.70 105.52 181.68 154.87 122.11 0.67 0.63 0.51 -0.34 -0.13 Covered/w/another[5845]
YPL111W CAR1 "Arginase, responsible for arginine degradation, expression responds to both induction by arginine and nitrogen catabolite repression; disruption enhances freeze tolerance" Verified chr16:339943-340944 339943-340944 98.4% 515.02 218.98 708.66 598.15 1171.97 1015.84 367.00 653.40 1093.90 1.35 2.65 4.53 0.74 0.93 Matched[5846]
YPL110C GDE1 "Glycerophosphocholine (GroPCho) phosphodiesterase; hydrolyzes GroPCho to choline and glycerolphosphate, for use as a phosphate source and as a precursor for phosphocholine synthesis; may interact with ribosomes" Verified chr16:341067-344738 341067-344738 99.2% 74.94 63.96 79.61 60.39 53.53 51.61 69.45 70.00 52.57 0.26 0.28 0.22 -0.41 0.28 Matched[5847]
YPL109C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr16:345263-347388 345263-345443,345596-347388 99.2% 41.38 47.00 39.34 42.40 77.65 55.17 44.19 40.87 66.41 0.16 0.17 0.28 0.70 0.97 Matched[5848]
YPL108W Cytoplasmic protein of unknown function; non-essential gene that is induced in a GDH1 deleted strain with altered redox metabolism; GFP-fusion protein is induced in response to the DNA-damaging agent MMS Uncharacterized chr16:348443-348949 348443-348949 98.2% 86.39 44.20 80.36 68.31 32.14 14.06 65.29 74.33 23.10 0.24 0.30 0.10 -1.69 -1.33 Covered/w/another[5850]
YPL107W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YPL107W is not an essential gene Uncharacterized chr16:349116-349862 349116-349862 98.2% 95.40 114.48 113.12 103.58 119.93 81.77 104.94 108.35 100.85 0.39 0.44 0.42 -0.10 -0.21 Matched[5850]
YPL106C SSE1 ATPase that is a component of the heat shock protein Hsp90 chaperone complex; binds unfolded proteins; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm Verified chr16:350191-352272 350191-352272 98.7% 1950.43 1349.74 1728.63 1789.43 7677.69 7949.58 1650.08 1759.03 7813.63 6.09 7.14 32.37 2.15 1.74 Frag>80[5851,5852,5853]
YPL105C "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr16:352860-355409 352860-355409 98.9% 396.95 352.14 346.98 308.12 230.00 246.65 374.54 327.55 238.33 1.38 1.33 0.99 -0.46 0.28 Matched[5854]
YPL104W MSD1 "Mitochondrial aspartyl-tRNA synthetase, required for acylation of aspartyl-tRNA; yeast and bacterial aspartyl-, asparaginyl-, and lysyl-tRNA synthetases contain regions with high sequence similarity, suggesting a common ancestral gene" Verified chr16:355697-357673 355697-357673 98.6% 91.83 105.68 110.81 112.35 140.05 133.38 98.75 111.58 136.71 0.36 0.45 0.57 0.29 0.82 Covered/w/another[5855]
YPL103C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr16:357997-359403 357997-359403 98.9% 77.60 91.25 98.43 74.01 89.81 76.16 84.42 86.22 82.99 0.31 0.35 0.34 -0.06 0.15 Covered/w/another[5855]
YPL101W ELP4 "Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity" Verified chr16:360206-361576 360206-361576 98.6% 150.96 127.28 139.86 102.86 56.24 31.08 139.12 121.36 43.66 0.51 0.49 0.18 -1.47 -0.86 Matched[5856]
YPL102C "Dubious open reading frame, not conserved in closely related Saccharomyces species; deletion mutation enhances replication of Brome mosaic virus in S. cerevisiae, but this is likely due to effects on the overlapping gene ELP4" Dubious chr16:360000-360302 360000-360302 98.2% 36.99 33.62 47.07 43.71 26.90 13.45 35.30 45.39 20.17 0.13 0.18 0.08 -1.17 0.32 Overlap[5856]
YPL100W ATG21 "Phosphatidylinositol 3,5-bisphosphate-binding protein required for maturation of pro-aminopeptidase I, predicted to fold as a seven-bladed beta-propeller; displays punctate cytoplasmic localization" Verified chr16:361869-363359 361869-363359 98.8% 127.56 107.21 109.24 109.24 210.34 139.78 117.38 109.24 175.06 0.43 0.44 0.73 0.68 0.73 Matched[5857]
YPL099C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr16:363517-364065 363517-364065 99.2% 152.40 128.53 168.92 167.09 293.78 167.09 140.46 168.01 230.43 0.52 0.68 0.95 0.46 -0.11 Frag<80[5858,5859]
YPL098C MGR2 Protein required for growth of cells lacking the mitochondrial genome Verified chr16:364383-364724 364383-364724 98.6% 361.75 391.40 406.23 426.98 539.66 426.98 376.58 416.60 483.32 1.39 1.69 2.00 0.21 0.29 Matched[5859]
YPL097W MSY1 Mitochondrial tyrosyl-tRNA synthetase Verified chr16:364949-366427 364949-366427 98.6% 75.39 71.97 84.30 55.52 140.51 98.01 73.68 69.91 119.26 0.27 0.28 0.49 0.77 0.77 Covered/w/another[5860]
YPL096C-A ERI1 Endoplasmic reticulum membrane protein that binds to and inhibits GTP-bound Ras2p at the ER; component of the GPI-GnT complex which catalyzes the first step in GPI-anchor biosynthesis; probable homolog of mammalian PIG-Y protein Verified chr16:366526-366732 366526-366732 98.4% 216.04 181.67 191.49 157.12 211.13 122.75 198.85 174.30 166.94 0.73 0.71 0.69 -0.06 NaN Covered/w/another[5860]
YPL096W PNG1 "Conserved peptide N-glycanase required for deglycosylation of misfolded glycoproteins during proteasome-dependent degradation, localizes to the cytoplasm and nucleus, interacts with the DNA repair protein Rad23p" Verified chr16:366924-368015 366924-368015 98.6% 136.57 145.86 125.42 120.78 196.96 136.57 141.21 123.10 166.76 0.52 0.50 0.69 0.44 0.30 Covered/w/another[5860]
YPL095C EEB1 Acyl-coenzymeA:ethanol O-acyltransferase responsible for the major part of medium-chain fatty acid ethyl ester biosynthesis during fermentation; possesses short chain esterase activity; may be involved in lipid metabolism and detoxification Verified chr16:368068-369438 368068-369438 99.0% 750.05 510.59 605.64 565.11 277.77 145.88 630.32 585.37 211.83 2.33 2.38 0.88 -1.47 -1.50 Matched[5861]
YPL094C SEC62 "Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER" Verified chr16:369836-370660 369836-370660 98.9% 795.02 711.72 709.27 645.57 526.75 365.05 753.37 677.42 445.90 2.78 2.75 1.85 -0.60 -0.49 Frag>80[5862,5863]
YPL093W NOG1 Putative GTPase that associates with free 60S ribosomal subunits in the nucleolus and is required for 60S ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; member of the ODN family of nucleolar G-proteins Verified chr16:370975-372918 370975-372918 98.6% 582.02 327.00 303.53 234.69 25.03 4.17 454.51 269.11 14.60 1.68 1.09 0.06 -4.20 -3.46 Frag>80[5864,5865]
YPL092W SSU1 Plasma membrane sulfite pump involved in sulfite metabolism and required for efficient sulfite efflux; major facilitator superfamily protein Verified chr16:373790-375166 373790-375166 98.9% 176.93 321.57 176.93 153.44 86.63 57.27 249.25 165.19 71.95 0.92 0.67 0.30 -1.20 -1.10 Matched[5866]
YPL091W GLR1 "Cytosolic and mitochondrial glutathione oxidoreductase, converts oxidized glutathione to reduced glutathione" Verified chr16:375499-376950 375499-376950 98.6% 681.66 562.23 720.08 657.22 687.95 565.03 621.95 688.65 626.49 2.30 2.80 2.60 -0.14 0.39 Matched[5867]
YPL090C RPS6A Protein component of the small (40S) ribosomal subunit; identical to Rps6Bp and has similarity to rat S6 ribosomal protein Verified chr16:377288-378392 377288-377992,378387-378392 13.2% 8173.84 5470.51 7247.89 5928.16 1564.52 1085.59 6822.17 6588.03 1325.06 25.18 26.74 5.49 -2.31 -3.68 Frag<80[5868,5869,5870]
YPL089C RLM1 "MADS-box transcription factor, component of the protein kinase C-mediated MAP kinase pathway involved in the maintenance of cell integrity; phosphorylated and activated by the MAP-kinase Slt2p" Verified chr16:379117-381147 379117-381147 98.1% 137.54 143.06 128.00 119.47 132.52 124.49 140.30 123.73 128.50 0.52 0.50 0.53 0.05 0.55 Covered/w/another[5871]
YPL088W Putative aryl alcohol dehydrogenase; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance Uncharacterized chr16:381962-382990 381962-382990 98.5% 56.24 56.24 33.54 27.62 51.30 35.52 56.24 30.58 43.41 0.21 0.12 0.18 0.51 0.28 Covered/w/another[5871]
YPL087W YDC1 "Alkaline dihydroceramidase, involved in sphingolipid metabolism; preferentially hydrolyzes dihydroceramide to a free fatty acid and dihydrosphingosine; has a minor reverse activity" Verified chr16:383452-384405 383452-384405 98.9% 380.36 608.16 432.28 471.48 1371.00 1011.83 494.26 451.88 1191.42 1.82 1.83 4.94 1.40 1.39 Matched[5872]
YPL086C ELP3 "Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; exhibits histone acetyltransferase activity that is directed to histones H3 and H4; disruption confers resistance to K. lactis zymotoxin" Verified chr16:384770-386443 384770-386443 99.3% 194.85 121.48 140.13 140.13 25.26 8.42 158.17 140.13 16.84 0.58 0.57 0.07 -3.06 -2.53 Matched[5873]
YPL085W SEC16 "COPII vesicle coat protein required for ER transport vesicle budding and autophagosome formation; Sec16p is bound to the periphery of ER membranes and may act to stabilize initial COPII complexes; interacts with Sec23p, Sec24p and Sec31p" Verified chr16:387064-393651 387064-393651 98.7% 162.94 158.33 144.80 135.73 55.34 142.65 160.64 140.27 98.99 0.59 0.57 0.41 -0.50 0.38 Matched[5874]
YPL084W BRO1 Cytoplasmic class E vacuolar protein sorting (VPS) factor that coordinates deubiquitination in the multivesicular body (MVB) pathway by recruiting Doa4p to endosomes Verified chr16:394035-396569 394035-396569 98.7% 131.03 163.78 156.99 150.60 239.28 231.69 147.41 153.80 235.49 0.54 0.62 0.98 0.61 1.00 Matched[5875]
YPL083C SEN54 "Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p" Verified chr16:396699-398102 396699-398102 99.0% 106.44 107.16 100.68 101.40 81.98 64.72 106.80 101.04 73.35 0.39 0.41 0.30 -0.46 -0.23 Matched[5876]
YPL082C MOT1 "Essential abundant protein involved in regulation of transcription, removes Spt15p (TBP) from DNA via its C-terminal ATPase activity, forms a complex with TBP that binds TATA DNA with high affinity but with altered specificity" Verified chr16:398477-404080 398477-404080 99.1% 102.84 89.69 66.46 49.35 32.78 53.13 96.27 57.90 42.96 0.36 0.24 0.18 -0.43 0.17 Matched[5877]
YPL081W RPS9A Protein component of the small (40S) ribosomal subunit; nearly identical to Rps9Bp and has similarity to E. coli S4 and rat S9 ribosomal proteins Verified chr16:404947-406041 404947-404953,405455-406041 72.1% 1285.88 1211.20 982.50 431.74 165.69 51.34 1248.54 707.12 108.52 4.61 2.87 0.45 -2.70 -2.68 Matched[5878]
YPL080C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr16:406169-406495 406169-406495 98.4% 124.29 105.64 83.89 21.75 31.07 9.32 114.97 52.82 20.20 0.42 0.21 0.08 -1.39 -0.34 Overlap[5878]
YPL079W RPL21B "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl21Ap and has similarity to rat L21 ribosomal protein" Verified chr16:406633-407536 406633-406643,407065-407536 58.9% 7820.58 6300.79 6824.98 5987.69 1438.87 1488.13 7060.69 6406.33 1463.50 26.06 26.00 6.06 -2.13 -2.08 Matched[5879]
YPL078C ATP4 "Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated" Verified chr16:408007-408741 408007-408741 99.1% 1264.75 1410.31 1325.17 1632.77 1969.22 1325.17 1337.53 1478.97 1647.19 4.94 6.00 6.82 0.16 -0.10 Frag>80[5880,5881]
YPL077C Putative protein of unknown function; regulates PIS1 expression; mutant displays spore wall assembly defect in ether sensitivity screen; YPL077C is not an essential gene Uncharacterized chr16:409365-410087 409365-410087 99.2% 43.22 41.82 39.04 46.01 78.07 41.82 42.52 42.52 59.95 0.16 0.17 0.25 0.50 0.96 Matched[5882]
YPL076W GPI2 "Protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-C protein" Verified chr16:410440-411282 410440-411282 99.3% 93.22 109.95 75.30 84.86 135.05 102.78 101.59 80.08 118.92 0.38 0.33 0.49 0.57 -0.32 Frag<80[5883]
YPL075W GCR1 Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and functions with the transcriptional activator Gcr2p Verified chr16:412251-415359 412251-412258,413010-415359 98.9% 297.30 295.59 232.52 177.18 197.34 169.89 296.44 204.85 183.62 1.09 0.83 0.76 -0.16 0.43 Matched[5885]
YPL074W YTA6 "Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family, localized to the cortex of mother cells but not to daughter cells" Verified chr16:415760-418024 415760-418024 98.4% 89.26 84.33 72.67 64.14 76.70 83.43 86.80 68.40 80.07 0.32 0.28 0.33 0.23 0.51 Covered/w/another[5886]
YPL072W UBP16 "Deubiquitinating enzyme anchored to the outer mitochondrial membrane, probably not important for general mitochondrial functioning, but may perform a more specialized function at mitochondria" Verified chr16:418509-420008 418509-420008 99.0% 106.43 113.84 107.10 103.74 98.35 79.49 110.14 105.42 88.92 0.41 0.43 0.37 -0.25 -0.01 Covered/w/another[5886]
YPL073C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps with verified gene UBP16/YPL072W; may interact with ribosome based on co-purification experiments" Dubious chr16:418496-418981 418496-418981 99.0% 76.88 93.50 95.58 116.35 78.95 89.34 85.19 105.96 84.15 0.31 0.43 0.35 -0.33 0.40 Covered/w/another[5886]
YPL071C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus Uncharacterized chr16:420045-420515 420045-420515 99.4% 155.96 162.36 106.82 91.86 213.64 153.82 159.16 99.34 183.73 0.59 0.40 0.76 0.89 0.53 Covered/w/another[5886]
YPL070W MUK1 Cytoplasmic protein of unknown function; computational analysis of large-scale protein-protein interaction data suggests a possible role in transcriptional regulation Verified chr16:420945-422783 420945-422783 99.0% 90.65 112.08 84.06 82.41 156.03 110.98 101.36 83.23 133.50 0.37 0.34 0.55 0.68 0.82 Matched[5887]
YPL069C BTS1 "Geranylgeranyl diphosphate synthase, increases the intracellular pool of geranylgeranyl diphosphate, suppressor of bet2 mutation that causes defective geranylgeranylation of small GTP-binding proteins that mediate vesicular traffic" Verified chr16:422882-423889 422882-423889 98.9% 92.25 101.27 93.25 95.25 70.19 42.11 96.76 94.25 56.15 0.36 0.38 0.23 -0.75 0.06 Matched[5888]
YPL068C Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and is induced in response to the DNA-damaging agent MMS Uncharacterized chr16:424212-425093 424212-425093 98.8% 57.40 53.96 57.40 43.62 19.52 12.63 55.68 50.51 16.07 0.21 0.21 0.07 -1.65 -1.44 Covered/w/another[5889]
YPL067C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YPL067C is not an essential gene Uncharacterized chr16:425248-425844 425248-425844 98.3% 97.13 59.64 64.75 52.83 95.43 57.94 78.39 58.79 76.68 0.29 0.24 0.32 0.38 0.30 Covered/w/another[5889]
YPL066W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the bud neck and cytoplasm; null mutant is viable and exhibits growth defect on a non-fermentable (respiratory) carbon source Uncharacterized chr16:426230-427669 426230-427669 99.2% 193.23 238.03 181.32 156.12 165.92 121.12 215.63 168.72 143.52 0.80 0.68 0.59 -0.23 0.49 Covered/w/another[5889]
YPL065W VPS28 "Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; involved in transport of precursors for soluble vacuolar hydrolases from the late endosome to the vacuole" Verified chr16:427924-428652 427924-428652 99.2% 186.65 171.44 152.08 146.55 309.70 161.76 179.04 149.32 235.73 0.66 0.61 0.98 0.66 0.45 Covered/w/another[5890]
YPL064C CWC27 "Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; has similarity to S. pombe Cwf27p" Verified chr16:428708-429613 428708-429613 99.4% 197.60 235.35 212.04 203.15 188.72 137.66 216.48 207.60 163.19 0.80 0.84 0.68 -0.35 -0.08 Covered/w/another[5890]
YPL063W TIM50 Constituent of the mitochondrial inner membrane presequence translocase (TIM23 complex); may promote binding of incoming precursor proteins to the intermembrane space domain of Tom22p during translocation Verified chr16:429936-431366 429936-431366 98.5% 604.17 599.91 639.62 592.82 424.05 350.30 602.04 616.22 387.18 2.22 2.50 1.60 -0.67 -0.36 Matched[5891]
YPL062W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPL062W is not an essential gene; homozygous diploid mutant shows a decrease in glycogen accumulation" Dubious chr16:431892-432296 431892-432296 97.8% 2.53 5.05 10.10 0.00 10.10 10.10 3.79 5.05 10.10 0.01 0.02 0.04 1.00 0.71 Frag<80[5892]
YPL061W ALD6 "Cytosolic aldehyde dehydrogenase, activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; required for conversion of acetaldehyde to acetate; constitutively expressed; locates to the mitochondrial outer surface upon oxidative stress" Verified chr16:432585-434087 432585-434087 98.7% 1024.69 2716.10 4473.58 3735.40 7822.03 4423.70 1870.40 4104.49 6122.86 6.90 16.66 25.37 0.58 -0.36 Matched[5893]
YPL060W LPE10 "Mitochondrial inner membrane magnesium transporter, involved in maintenance of magnesium concentrations inside mitochondria; indirectly affects splicing of group II introns; functionally and structurally related to Mrs2p" Verified chr16:434520-435761 434520-435761 98.9% 39.09 39.91 42.35 39.91 85.51 65.97 39.50 41.13 75.74 0.15 0.17 0.31 0.88 0.77 Matched[5894]
YPL059W GRX5 Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; mitochondrial matrix protein involved in the synthesis/assembly of iron-sulfur centers; monothiol glutaredoxin subfamily member along with Grx3p and Grx4p Verified chr16:444576-445028 444576-445028 98.4% 536.02 542.75 603.31 464.26 760.30 533.78 539.39 533.78 647.04 1.99 2.17 2.68 0.28 0.02 Matched[5895]
YPL058C PDR12 "Plasma membrane ATP-binding cassette (ABC) transporter, weak-acid-inducible multidrug transporter required for weak organic acid resistance; induced by sorbate and benzoate and regulated by War1p; mutants exhibit sorbate hypersensitivity" Verified chr16:445839-450374 445839-450374 98.9% 353.45 264.70 178.18 182.41 103.69 185.09 309.08 180.29 144.39 1.14 0.73 0.60 -0.32 0.68 Frag>80[5896,5897,5898]
YPL057C SUR1 "Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synthase, forms a complex with probable regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Csh1p" Verified chr16:451906-453054 451906-453054 98.9% 176.09 251.81 218.35 174.33 270.30 192.82 213.95 196.34 231.56 0.79 0.80 0.96 0.24 0.58 Matched[5900]
YPL056C Putative protein of unknown function; deletion mutant is fluconazole resistant Uncharacterized chr16:453427-453732 453427-453732 97.3% 90.68 124.27 80.60 60.45 134.34 40.30 107.47 70.53 87.32 0.40 0.29 0.36 0.31 0.01
YPL055C LGE1 Protein of unknown function; null mutant forms abnormally large cells Verified chr16:453989-454987 453989-454987 99.0% 136.55 167.90 160.82 144.64 172.96 138.57 152.23 152.73 155.77 0.56 0.62 0.65 0.03 -0.09 Matched[5901]
YPL054W LEE1 Zinc-finger protein of unknown function Verified chr16:455756-456661 455756-456661 99.2% 37.84 52.30 71.22 57.87 90.14 53.41 45.07 64.54 71.78 0.17 0.26 0.30 0.15 0.50 Matched[5902]
YPL053C KTR6 Probable mannosylphosphate transferase involved in the synthesis of core oligosaccharides in protein glycosylation pathway; member of the KRE2/MNT1 mannosyltransferase family Verified chr16:457115-458455 457115-458455 99.4% 309.98 267.95 276.21 291.22 210.91 144.11 288.97 283.71 177.51 1.07 1.15 0.74 -0.68 -0.56 Matched[5903]
YPL052W OAZ1 "Regulator of ornithine decarboxylase (Spe1p), antizyme that binds to Spe1p to regulate ubiquitin-independent degradation; ribosomal frameshifting during synthesis of Oaz1p and its ubiquitin-mediated degradation are both polyamine-regulated" Verified chr16:458796-459675 458796-459675 99.1% 61.91 75.67 45.86 29.81 64.20 38.98 68.79 37.83 51.59 0.25 0.15 0.21 0.45 -0.53 Frag>80[5904,5905]
YPL051W ARL3 GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to ADP-ribosylation factor Verified chr16:459960-460556 459960-460556 98.3% 107.31 115.83 110.72 110.72 103.90 74.95 111.57 110.72 89.43 0.41 0.45 0.37 -0.31 -0.42 Matched[5906]
YPL050C MNN9 "Subunit of Golgi mannosyltransferase complex also containing Anp1p, Mnn10p, Mnn11p, and Hoc1p that mediates elongation of the polysaccharide mannan backbone; forms a separate complex with Van1p that is also involved in backbone elongation" Verified chr16:460776-461963 460776-461963 99.1% 674.19 501.82 561.26 521.35 298.04 206.33 588.01 541.31 252.18 2.17 2.20 1.04 -1.10 -0.61 Matched[5907]
YPL049C DIG1 "Regulatory protein of unknown function, constitutively-expressed, involved in the regulation of mating-specific genes and the invasive growth pathway, required for MAP-kinase imposed repression, inhibits pheromone-responsive transcription" Verified chr16:462478-463836 462478-463836 98.4% 421.84 560.21 458.49 388.93 341.06 279.73 491.02 423.71 310.40 1.81 1.72 1.29 -0.45 0.03 Matched[5908]
YPL048W CAM1 Nuclear protein required for transcription of MXR1; binds the MXR1 promoter in the presence of other nuclear factors; binds calcium and phospholipids; has similarity to translational cofactor EF-1 gamma Verified chr16:464398-465645 464398-465645 95.8% 1166.53 1394.14 1230.13 1092.05 1326.36 1052.72 1280.33 1161.09 1189.54 4.73 4.71 4.93 0.03 0.17 Matched[5909]
YPL047W SGF11 "Integral subunit of SAGA histone acetyltransferase complex, regulates transcription of a subset of SAGA-regulated genes, required for the Ubp8p association with SAGA and for H2B deubiquitylation" Verified chr16:465959-466258 465959-466258 98.5% 213.20 216.58 182.74 152.28 162.44 67.68 214.89 167.51 115.06 0.79 0.68 0.48 -0.54 -0.58 Covered/w/another[5910]
YPL046C ELC1 "Elongin C, forms heterodimer with Ela1p that participates in transcription elongation; required for ubiquitin-dependent degradation of the RNA Polymerase II subunit RPO21; expression dramatically upregulated during sporulation" Verified chr16:466641-466940 466641-466940 99.3% 93.99 87.27 93.99 120.84 164.48 177.90 90.63 107.41 171.19 0.33 0.44 0.71 0.67 -0.03 Covered/w/another[5910]
YPL045W VPS16 Subunit of the vacuole fusion and protein sorting HOPS complex and the CORVET tethering complex; part of the Class C Vps complex essential for membrane docking and fusion at Golgi-to-endosome and endosome-to-vacuole protein transport stages Verified chr16:467257-469653 467257-469653 98.8% 110.25 115.32 78.57 96.74 106.87 91.67 112.79 87.65 99.27 0.42 0.36 0.41 0.18 0.19 Matched[5911]
YPL043W NOP4 "Nucleolar protein, essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; contains four RNA recognition motifs (RRMs)" Verified chr16:469936-471993 469936-471993 98.1% 428.24 172.28 246.54 189.61 22.28 4.95 300.26 218.08 13.61 1.11 0.89 0.06 -4.00 -4.42 Matched[5912]
YPL044C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene NOP4/YPL043W" Dubious chr16:469923-470471 469923-470471 98.2% 257.92 102.06 139.17 120.61 11.13 3.71 179.99 129.89 7.42 0.66 0.53 0.03 -4.13 -1.19 Covered/w/another[5912]
YPL042C SSN3 "Cyclin-dependent protein kinase, component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression" Verified chr16:473037-474704 473037-474704 99.1% 94.98 96.19 85.30 68.97 118.57 83.48 95.58 77.13 101.03 0.35 0.31 0.42 0.39 0.64 Covered/w/another[5913]
YPL041C Protein of unknown function involved in maintenance of proper telomere length Uncharacterized chr16:475115-475738 475115-475738 98.7% 66.55 79.54 51.94 58.44 97.40 45.45 73.05 55.19 71.42 0.27 0.22 0.30 0.37 0.21 Covered/w/another[5913]
YPL040C ISM1 "Mitochondrial isoleucyl-tRNA synthetase, null mutant is deficient in respiratory growth" Verified chr16:475990-478998 475990-478998 99.1% 62.02 65.37 58.33 54.98 49.95 45.26 63.70 56.66 47.61 0.24 0.23 0.20 -0.25 -0.01 Covered/w/another[5913]
YPL039W Putative protein of unknown function; YPL039W is not an essential gene Uncharacterized chr16:479222-480172 479222-480172 98.7% 88.43 82.04 77.78 82.04 119.33 79.91 85.23 79.91 99.62 0.31 0.32 0.41 0.32 0.26 Covered/w/another[5914]
YPL038W-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr16:480179-480370 480179-480370 99.3% 68.20 57.70 62.95 47.21 41.97 36.72 62.95 55.08 39.34 0.23 0.22 0.16 -0.49 NaN Covered/w/another[5914]
YPL038W MET31 "Zinc-finger DNA-binding protein, involved in transcriptional regulation of the methionine biosynthetic genes, similar to Met32p" Verified chr16:480532-481065 480532-481065 98.3% 184.88 156.29 141.04 104.83 188.69 114.36 170.58 122.94 151.52 0.63 0.50 0.63 0.30 -0.25 Covered/w/another[5914]
YPL037C EGD1 "Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in protein targeting, associated with cytoplasmic ribosomes; enhances DNA binding of the Gal4p activator; homolog of human BTF3b" Verified chr16:481425-481898 481425-481898 98.7% 5233.84 4419.59 4842.74 4443.10 3579.70 2788.96 4826.71 4642.92 3184.33 17.82 18.85 13.19 -0.54 -1.36 Matched[5915]
YPL036W PMA2 "Plasma membrane H+-ATPase, isoform of Pma1p, involved in pumping protons out of the cell; regulator of cytoplasmic pH and plasma membrane potential" Verified chr16:482841-485684 482841-485684 87.9% 20.79 19.59 17.19 9.60 14.79 20.39 20.19 13.39 17.59 0.07 0.05 0.07 0.39 -0.23 Frag<80[5916,5917]
YPL034W Putative protein of unknown function; YPL034W is not essential gene Uncharacterized chr16:486710-487207 486710-487207 98.9% 166.57 178.76 121.88 91.41 201.10 105.63 172.66 106.64 153.36 0.64 0.43 0.64 0.52 0.57 Matched[5918]
YPL035C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YPL034W; YPL035C is not an essential gene" Dubious chr16:486562-486909 486562-486909 98.7% 130.96 125.14 116.41 98.95 139.69 125.14 128.05 107.68 132.41 0.47 0.44 0.55 0.30 -0.06 Matched[5918]
YPL033C Putative protein of unknown function; may be involved in DNA metabolism; expression is induced by Kar4p Uncharacterized chr16:487360-488205 487360-488205 99.3% 2.38 0.00 2.38 4.76 5.95 7.14 1.19 3.57 6.54 0.00 0.01 0.03 0.87 0.29 Frag<80[5919]
YPL032C SVL3 "Protein of unknown function, mutant phenotype suggests a potential role in vacuolar function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck" Verified chr16:488885-491362 488885-491362 98.9% 501.07 436.60 381.11 380.70 132.61 147.30 468.84 380.90 139.96 1.73 1.55 0.58 -1.44 -0.46 Frag>80[5920,5921,5922]
YPL031C PHO85 "Cyclin-dependent kinase, with ten cyclin partners; involved in environmental stress response; in phosphate-rich conditions, Pho85p-Pho80p complex phosphorylates Pho4p which in turn represses PHO5" Verified chr16:492016-493035 492016-492916,493019-493035 98.8% 286.73 317.60 281.21 233.79 436.70 328.63 302.16 257.50 382.67 1.12 1.05 1.59 0.57 0.69 Matched[5923]
YPL030W Putative tRNA U44 2'-O-methyltransferase; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; non-essential gene Verified chr16:493541-495244 493541-495244 98.8% 106.95 97.44 90.90 71.89 29.71 14.85 102.19 81.40 22.28 0.38 0.33 0.09 -1.87 -1.52 Matched[5924]
YPL029W SUV3 "ATP-dependent RNA helicase, component of the mitochondrial degradosome along with the RNase Dss1p; the degradosome associates with the ribosome and mediates turnover of aberrant or unprocessed RNAs" Verified chr16:495504-497717 495504-497717 98.8% 60.36 59.45 49.85 45.27 42.07 35.21 59.91 47.56 38.64 0.22 0.19 0.16 -0.30 0.00 Frag>80[5925]
YPL028W ERG10 "Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase), cytosolic enzyme that transfers an acetyl group from one acetyl-CoA molecule to another, forming acetoacetyl-CoA; involved in the first step in mevalonate biosynthesis" Verified chr16:498094-499290 498094-499290 98.6% 1011.58 996.33 1032.76 804.01 722.68 524.43 1003.95 918.38 623.55 3.71 3.73 2.58 -0.56 -0.19 Matched[5926]
YPL027W SMA1 Protein of unknown function involved in the assembly of the prospore membrane during sporulation Verified chr16:499663-500400 499663-500400 98.6% 5.50 2.75 6.87 5.50 5.50 8.25 4.12 6.18 6.87 0.02 0.03 0.03 0.15 0.23 Overlap[5927]
YPL026C SKS1 Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway Verified chr16:500673-502181 500673-502181 98.4% 166.98 199.30 136.68 138.03 34.34 26.26 183.14 137.36 30.30 0.68 0.56 0.13 -2.18 -1.41 Matched[5927]
YPL025C Hypothetical protein Dubious chr16:502471-503028 502471-503028 98.1% 18.27 12.79 12.79 7.31 3.65 21.92 15.53 10.05 12.79 0.06 0.04 0.05 0.35 -0.52 Overlap[5928]
YPL024W RMI1 Involved in response to DNA damage; null mutants have increased rates of recombination and delayed S phase; interacts physically and genetically with Sgs1p (RecQ family member) and Top3p (topoisomerase III) Verified chr16:503515-504240 503515-504240 98.5% 60.14 41.96 64.34 19.58 92.31 54.55 51.05 41.96 73.43 0.19 0.17 0.30 0.81 0.65 Matched[5928]
YPL023C MET12 "Isozyme of methylenetetrahydrofolate reductase, catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate in the methionine biosynthesis pathway" Verified chr16:504337-506310 504337-506310 99.0% 160.12 153.47 173.94 157.56 165.24 145.29 156.80 165.75 155.26 0.58 0.67 0.64 -0.09 0.10 Matched[5929]
YPL022W RAD1 "Single-stranded DNA endonuclease (with Rad10p), cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human XPF protein" Verified chr16:506695-509997 506695-509997 98.7% 115.97 112.60 103.39 96.03 79.16 68.11 114.29 99.71 73.63 0.42 0.40 0.31 -0.44 0.22 Matched[5930]
YPL021W ECM23 "Non-essential protein of unconfirmed function; affects pre-rRNA processing, may act as a negative regulator of the transcription of genes involved in pseudohyphal growth; homologous to Srd1p" Verified chr16:511099-511662 511099-511662 98.7% 0.00 1.80 0.00 1.80 0.00 1.80 0.90 0.90 0.90 0.00 0.00 0.00 0.00 -0.04
YPL020C ULP1 Ubl (ubiquitin-like protein)-specific protease that cleaves Smt3p protein conjugates; specifically required for cell cycle progression; associates with nucleoporins and may interact with septin rings during telophase Verified chr16:512311-514176 512311-514176 99.4% 154.71 149.32 146.62 122.91 138.00 94.87 152.01 134.76 116.44 0.56 0.55 0.48 -0.21 -0.09 Frag>80[5931,5932,5933]
YPL019C VTC3 Vacuolar membrane protein involved in vacuolar polyphosphate accumulation; functions as a regulator of vacuolar H+-ATPase activity and vacuolar transporter chaperones; involved in non-autophagic vacuolar fusion Verified chr16:514509-517016 514509-517016 99.2% 1304.73 1007.69 1367.03 1144.35 432.10 299.45 1156.21 1255.69 365.77 4.27 5.10 1.52 -1.78 -1.53 Frag>80[5933,5934]
YPL018W CTF19 "Outer kinetochore protein, required for accurate mitotic chromosome segregation; component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p) that functions as a platform for kinetochore assembly" Verified chr16:517649-518758 517649-518758 98.6% 74.92 150.75 71.27 47.51 220.19 99.59 112.84 59.39 159.89 0.42 0.24 0.66 1.43 -0.12 Frag<80[5935]
YPL017C Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; null mutant displays increased levels of spontaneous Rad52 foci Uncharacterized chr16:518732-520231 518732-520231 98.8% 99.23 143.11 95.86 83.03 179.56 132.98 121.17 89.44 156.27 0.45 0.36 0.65 0.81 2.03 Matched[5936]
YPL016W SWI1 "Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2" Verified chr16:521011-524955 521011-524955 98.3% 82.26 69.88 67.04 43.58 31.20 27.33 76.07 55.31 29.27 0.28 0.22 0.12 -0.92 -0.14 Frag>80[5937,5938]
YPL015C HST2 Cytoplasmic member of the silencing information regulator 2 (Sir2) family of NAD(+)-dependent protein deacetylases; modulates nucleolar (rDNA) and telomeric silencing; possesses NAD(+)-dependent histone deacetylase activity in vitro Verified chr16:525807-526880 525807-526880 98.8% 265.81 235.65 279.00 187.57 364.78 229.05 250.73 233.29 296.91 0.93 0.95 1.23 0.35 0.46 Matched[5939]
YPL014W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus Uncharacterized chr16:527544-528689 527544-528689 99.1% 123.30 117.14 120.66 102.17 488.81 353.17 120.22 111.41 420.99 0.44 0.45 1.74 1.92 1.41 Matched[5940]
YPL013C MRPS16 Mitochondrial ribosomal protein of the small subunit Verified chr16:528982-529347 528982-529347 99.4% 728.11 733.60 692.39 626.45 566.00 425.87 730.85 659.42 495.94 2.70 2.68 2.05 -0.41 -0.81 Matched[5941]
YPL012W RRP12 Protein required for export of the ribosomal subunits; associates with the RNA components of the pre-ribosomes; contains HEAT-repeats Verified chr16:529720-533406 529720-533406 98.9% 211.50 89.15 118.51 84.22 11.80 3.84 150.33 101.36 7.82 0.55 0.41 0.03 -3.70 -3.22 Matched[5942]
YPL011C TAF3 "TFIID subunit (47 kDa), involved in promoter binding and RNA polymerase II transcription initiation" Verified chr16:533639-534700 533639-534700 99.2% 119.64 130.09 127.24 83.56 90.21 59.82 124.87 105.40 75.01 0.46 0.43 0.31 -0.49 -0.11 Matched[5943]
YPL010W RET3 "Zeta subunit of the coatomer complex (COPI), which coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ER" Verified chr16:535015-535584 535015-535584 98.7% 992.29 1040.31 981.62 933.61 1179.02 768.23 1016.30 957.62 973.62 3.75 3.89 4.03 0.02 -0.60 Matched[5944]
YPL009C "Protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YPL009C is not an essential gene" Verified chr16:535817-538933 535817-538933 97.0% 351.00 310.64 280.54 270.95 254.40 342.07 330.82 275.74 298.24 1.22 1.12 1.24 0.11 0.55 Matched[5945]
YPL008W CHL1 "Conserved nuclear protein required to establish sister-chromatid pairing during S-phase, probable DNA helicase with similarity to human BACH1, which associates with tumor suppressor BRCA1; associates with acetyltransferase Ctf7p" Verified chr16:539382-541967 539382-541967 98.8% 96.24 104.46 84.11 82.55 52.82 41.86 100.35 83.33 47.34 0.37 0.34 0.20 -0.82 -0.53 Covered/w/another[5946]
YPL007C TFC8 One of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); part of TFIIIC TauB domain that binds BoxB promoter sites of tRNA and other genes; linker between TauB and TauA domains; human homolog is TFIIIC-90 Verified chr16:542079-543845 542079-543845 99.3% 90.07 107.75 71.26 72.97 86.08 70.69 98.91 72.12 78.39 0.37 0.29 0.32 0.12 0.28 Covered/w/another[5946]
YPL006W NCR1 "Vacuolar membrane protein that transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; glycoprotein and functional orthologue of human Niemann Pick C1 (NPC1) protein" Verified chr16:544628-548140 544628-548140 98.9% 123.74 192.81 135.25 130.94 161.73 220.43 158.27 133.09 191.08 0.58 0.54 0.79 0.52 1.01 Frag>80[5947,5948,5949]
YPL005W AEP3 "Peripheral mitochondrial inner membrane protein, located on the matrix face of the membrane; stabilizes the bicistronic AAP1-ATP6 mRNA encoding subunits 6 and 8 of the ATP synthase complex" Verified chr16:548483-550303 548483-550303 98.7% 37.26 34.48 40.60 37.82 89.54 75.08 35.87 39.21 82.31 0.13 0.16 0.34 1.07 0.87 Matched[5950]
YPL004C LSP1 "Primary component of eisosomes, which are large immobile patch structures at the cell cortex associated with endocytosis, along with Pil1p and Sur7p; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways" Verified chr16:550629-551654 550629-551654 99.0% 1757.32 2084.17 2922.96 3080.48 7300.02 5820.33 1920.75 3001.72 6560.18 7.09 12.18 27.18 1.13 0.22 Frag>80[5951,5952,5953]
YPL003W ULA1 "Protein that acts together with Uba3p to activate Rub1p before its conjugation to proteins (neddylation), which may play a role in protein degradation" Verified chr16:552017-553405 552017-553405 98.8% 78.71 95.47 104.94 56.84 274.01 113.69 87.09 80.89 193.85 0.32 0.33 0.80 1.26 0.87 Covered/w/another[5954]
YPL002C SNF8 "Component of the ESCRT-II complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; appears to be functionally related to SNF7; involved in glucose derepression" Verified chr16:553624-554325 553624-554325 99.3% 120.44 151.99 144.82 110.41 187.84 110.41 136.22 127.61 149.12 0.50 0.52 0.62 0.22 0.26 Covered/w/another[5954]
YPL001W HAT1 "Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex that uses the cofactor acetyl coenzyme A, to acetylate free nuclear and cytoplasmic histone H4; involved in telomeric silencing and DNA double-strand break repair" Verified chr16:554602-555726 554602-555726 98.8% 91.79 66.59 101.69 74.69 110.69 65.69 79.19 88.19 88.19 0.29 0.36 0.37 0.00 -0.43 Matched[5955]
YPR001W CIT3 Dual specificity mitochondrial citrate and methylcitrate synthase; catalyzes the condensation of acetyl-CoA and oxaloacetate to form citrate and that of propionyl-CoA and oxaloacetate to form 2-methylcitrate Verified chr16:556374-557834 556374-557834 98.8% 31.19 29.80 27.03 27.03 36.73 25.64 30.49 27.03 31.19 0.11 0.11 0.13 0.21 0.38 Covered/w/another[5956]
YPR002W PDH1 "Mitochondrial protein that participates in respiration, induced by diauxic shift; homologous to E. coli PrpD, may take part in the conversion of 2-methylcitrate to 2-methylisocitrate" Verified chr16:558382-559932 558382-559932 98.7% 23.51 27.43 22.20 18.94 38.53 33.96 25.47 20.57 36.24 0.09 0.08 0.15 0.82 0.54 Covered/w/another[5956]
YPR002C-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the Ty1 long terminal repeat, YPRWdelta12" Dubious chr16:560566-560763 560566-560763 2.5% 203.39 0.00 0.00 203.39 203.39 0.00 101.69 101.69 101.69 0.38 0.41 0.42 0.00 0.09
YPR003C Putative sulfate permease; physically interacts with Hsp82p; green fluorescent protein (GFP)-fusion protein localizes to the ER; YPR003C is not an essential gene Uncharacterized chr16:561501-563765 561501-563765 98.6% 60.01 79.72 69.87 62.70 106.15 63.60 69.87 66.28 84.87 0.26 0.27 0.35 0.36 0.03 Matched[5958]
YPR004C Protein with homology to mammalian electron transfer flavoprotein complex subunit ETF-alpha; has an FAD binding domain; interacts with yeast frataxin homolog Yfh1p; associates with a large complex containing several dehydrogenases Verified chr16:564004-565038 564004-565038 98.9% 552.94 527.54 568.57 549.03 439.61 322.38 540.24 558.80 381.00 1.99 2.27 1.58 -0.55 -0.31 Frag>80[5959,5960,5961]
YPR005C HAL1 "Cytoplasmic protein involved in halotolerance; decreases intracellular Na+ (via Ena1p) and increases intracellular K+ by decreasing efflux; expression repressed by Ssn6p-Tup1p and Sko1p and induced by NaCl, KCl, and sorbitol through Gcn4p" Verified chr16:565784-566668 565784-566668 99.2% 86.61 76.35 76.35 54.70 83.19 55.84 81.48 65.53 69.52 0.30 0.27 0.29 0.09 1.21 Matched[5962]
YPR006C ICL2 "2-methylisocitrate lyase of the mitochondrial matrix, functions in the methylcitrate cycle to catalyze the conversion of 2-methylisocitrate to succinate and pyruvate; ICL2 transcription is repressed by glucose and induced by ethanol" Verified chr16:567266-568993 567266-568993 99.1% 64.25 50.82 51.40 55.49 125.59 72.43 57.54 53.45 99.01 0.21 0.22 0.41 0.89 0.39 Frag<80[5963,5964]
YPR007C REC8 Meiosis-specific component of sister chromatid cohesion complex; maintains cohesion between sister chromatids during meiosis I; maintains cohesion between centromeres of sister chromatids until meiosis II; homolog of S. pombe Rec8p Verified chr16:569333-571375 569333-571375 99.2% 2.96 5.43 1.97 0.99 5.92 3.95 4.19 1.48 4.93 0.02 0.01 0.02 1.74 0.51
YPR008W HAA1 "Transcriptional activator involved in the transcription of TPO2, HSP30 and other genes encoding membrane stress proteins; despite sequence similarity with the transcription factor Ace1p, it is not subject to metalloregulation" Verified chr16:573015-575099 573015-575099 98.8% 196.57 220.84 186.38 199.48 313.54 301.89 208.70 192.93 307.72 0.77 0.78 1.27 0.67 1.18 Matched[5965]
YPR009W SUT2 Putative transcription factor; multicopy suppressor of mutations that cause low activity of the cAMP/protein kinase A pathway; highly similar to Sut1p Verified chr16:576549-577355 576549-577355 98.9% 175.37 190.40 155.32 130.27 217.95 131.52 182.88 142.80 174.74 0.68 0.58 0.72 0.29 0.24 Matched[5966]
YPR010C RPA135 RNA polymerase I subunit A135 Verified chr16:577582-581193 577582-581193 98.9% 422.36 240.71 230.63 166.26 19.87 9.24 331.53 198.44 14.55 1.22 0.81 0.06 -3.77 -3.28 Matched[5967]
YPR010C-A Putative protein of unknown function; conserved among Saccharomyces sensu stricto species Uncharacterized chr16:582370-582731 582370-582555,582699-582731 99.4% 243.44 293.97 390.43 560.38 748.71 417.99 268.71 475.41 583.35 0.99 1.93 2.42 0.30 NaN Frag>80[5968,5969]
YPR011C "Putative transporter, member of the mitochondrial carrier family; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Uncharacterized chr16:583059-584039 583059-584039 99.1% 127.57 133.74 132.72 135.80 177.98 125.51 130.66 134.26 151.75 0.48 0.54 0.63 0.18 0.27 Covered/w/another[5970]
YPR012W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPR012W is not an essential gene" Dubious chr16:584306-584560 584306-584560 99.5% 82.80 118.28 59.14 27.60 67.03 15.77 100.54 43.37 41.40 0.37 0.18 0.17 -0.07 -0.49 Covered/w/another[5970]
YPR013C Putative zinc finger protein; YPR013C is not an essential gene Uncharacterized chr16:584629-585582 584629-585582 98.8% 95.46 156.97 81.67 68.94 114.55 94.40 126.22 75.30 104.47 0.47 0.31 0.43 0.47 0.90 Covered/w/another[5970]
YPR014C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPR014C is not an essential gene" Dubious chr16:587186-587515 587186-587515 98.5% 67.71 58.48 58.48 46.17 89.25 15.39 63.09 52.32 52.32 0.23 0.21 0.22 0.00 -0.15 Matched[5971]
YPR015C Putative protein of unknown function Uncharacterized chr16:590280-591023 590280-591023 98.5% 12.28 62.78 19.11 9.55 46.40 28.66 37.53 14.33 37.53 0.14 0.06 0.16 1.39 1.80 Matched[5972]
YPR016C TIF6 "Constituent of 66S pre-ribosomal particles, has similarity to human translation initiation factor 6 (eIF6); may be involved in the biogenesis and or stability of 60S ribosomal subunits" Verified chr16:592329-593066 592329-593066 98.9% 843.74 676.64 667.05 610.89 236.96 160.26 760.19 638.97 198.61 2.81 2.59 0.82 -1.69 -1.39 Matched[5974]
YPR016W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr16:593093-593353 593093-593353 99.0% 181.85 158.63 158.63 147.03 19.35 34.82 170.24 152.83 27.08 0.63 0.62 0.11 -2.50 -0.01 Frag<80[5975]
YPR017C DSS4 "Nucleotide release factor functioning in the post-Golgi secretory pathway, required for ER-to-Golgi transport, binds zinc, found both on membranes and in the cytosol; guanine nucleotide dissociation stimulator" Verified chr16:593483-593914 593483-593914 99.2% 240.26 247.25 216.93 191.27 58.31 65.31 243.76 204.10 61.81 0.90 0.83 0.26 -1.72 -1.44 Matched[5975]
YPR018W RLF2 Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) with Cac2p and Msi1p that assembles newly synthesized histones onto recently replicated DNA; involved in the maintenance of transcriptionally silent chromatin Verified chr16:594473-596293 594473-596293 98.3% 142.99 126.79 107.24 94.95 58.65 35.75 134.89 101.10 47.20 0.50 0.41 0.20 -1.10 -0.81 Covered/w/another[5976]
YPR019W MCM4 Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexes on DNA and melt the DNA prior to replication; accumulates in the nucleus in G1; homolog of S. pombe Cdc21p Verified chr16:596747-599548 596747-599548 98.7% 124.69 116.38 114.93 93.61 95.05 112.40 120.53 104.27 103.73 0.44 0.42 0.43 -0.01 0.63 Covered/w/another[5976]
YPR020W ATP20 Subunit g of the mitochondrial F1F0 ATP synthase; reversibly phosphorylated on two residues; unphosphorylated form is required for dimerization of the ATP synthase complex Verified chr16:599867-600214 599867-600214 99.0% 507.74 458.41 522.24 617.99 667.31 513.54 483.08 570.12 590.43 1.78 2.31 2.45 0.05 -0.62 Matched[5977]
YPR021C AGC1 "Mitochondrial amino acid transporter, acts both as a glutamate uniporter and as an aspartate-glutamate exchanger; involved in nitrogen metabolism and nitrogen compound biosynthesis" Verified chr16:600646-603354 600646-603354 99.2% 121.28 158.49 113.84 105.66 108.63 83.71 139.89 109.75 96.17 0.52 0.45 0.40 -0.19 0.14 Matched[5978]
YPR022C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus and is induced in response to the DNA-damaging agent MMS Uncharacterized chr16:603908-607309 603908-607309 98.6% 100.76 93.01 82.27 69.75 32.79 42.33 96.88 76.01 37.56 0.36 0.31 0.16 -1.02 -0.44 Covered[5979]
YPR023C EAF3 "Esa1p-associated factor, nonessential component of the NuA4 acetyltransferase complex, homologous to Drosophila dosage compensation protein MSL3" Verified chr16:608823-610028 608823-610028 99.0% 275.44 293.02 293.86 254.51 325.67 257.86 284.23 274.18 291.76 1.05 1.11 1.21 0.09 0.25 Frag>80[5980,5981]
YPR024W YME1 "Subunit, with Mgr1p, of the mitochondrial inner membrane i-AAA protease complex, which is responsible for degradation of unfolded or misfolded mitochondrial gene products; mutation causes an elevated rate of mitochondrial turnover" Verified chr16:610478-612721 610478-612721 98.6% 196.17 173.57 222.83 202.04 307.36 298.77 184.87 212.44 303.06 0.68 0.86 1.26 0.51 1.50 Matched[5982]
YPR025C CCL1 "Cyclin associated with protein kinase Kin28p, which is the TFIIH-associated carboxy-terminal domain (CTD) kinase involved in transcription initiation at RNA polymerase II promoters" Verified chr16:613374-614555 613374-614555 99.2% 167.14 192.72 169.70 144.12 227.69 133.03 179.93 156.91 180.36 0.66 0.64 0.75 0.20 -0.09 Matched[5983]
YPR026W ATH1 Acid trehalase required for utilization of extracellular trehalose Verified chr16:615376-619011 615376-619011 98.9% 35.32 55.63 54.52 47.84 157.43 179.40 45.48 51.18 168.41 0.17 0.21 0.70 1.72 2.13 Matched[5985]
YPR027C Putative protein of unknown function Uncharacterized chr16:620422-621255 620422-621255 99.1% 112.57 123.47 99.26 119.84 105.31 71.42 118.02 109.55 88.36 0.44 0.44 0.37 -0.31 -0.05 Matched[5987]
YPR028W YOP1 Membrane protein that interacts with Yip1p to mediate membrane traffic; overexpression results in cell death and accumulation of internal cell membranes; regulates vesicular traffic in stressed cells Verified chr16:623524-624199 623524-623574,623708-624199 99.1% 2106.83 2495.12 2222.02 2233.16 5228.05 3195.54 2300.98 2227.59 4211.80 8.49 9.04 17.45 0.92 0.28 Matched[5990]
YPR029C APL4 "Gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in vesicle mediated transport" Verified chr16:624466-626964 624466-626964 99.2% 187.61 178.33 165.83 177.53 155.74 139.60 182.97 171.68 147.67 0.68 0.70 0.61 -0.22 0.01 Matched[5991]
YPR030W CSR2 Nuclear protein with a potential regulatory role in utilization of galactose and nonfermentable carbon sources; overproduction suppresses the lethality at high temperature of a chs5 spa2 double null mutation; potential Cdc28p substrate Verified chr16:627877-631242 627877-631242 98.9% 14.42 20.12 23.73 30.64 54.36 42.05 17.27 27.18 48.21 0.06 0.11 0.20 0.83 1.26 Frag>80[5992,5993]
YPR031W NTO1 Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3 Verified chr16:631512-633758 631512-633758 98.8% 69.84 68.04 48.66 41.90 37.85 22.08 68.94 45.28 29.96 0.25 0.18 0.12 -0.60 -0.70 Matched[5994]
YPR032W SRO7 "Putative effector of Rab GTPase Sec4p, forms a complex with Sec4p and t-SNARE Sec9p; involved in exocytosis and docking and fusion of post-Golgi vesicles with plasma membrane; homolog of Sro77p and Drosophila lgl tumor suppressor" Verified chr16:634120-637221 634120-637221 98.8% 63.63 52.54 55.48 60.37 53.19 59.07 58.09 57.92 56.13 0.21 0.24 0.23 -0.05 0.55 Matched[5995]
YPR033C HTS1 Cytoplasmic and mitochondrial histidine tRNA synthetase; encoded by a single nuclear gene that specifies two messages; efficient mitochondrial localization requires both a presequence and an amino-terminal sequence Verified chr16:637376-639016 637376-639016 99.0% 818.42 683.04 749.50 732.27 236.91 255.99 750.73 740.89 246.45 2.77 3.01 1.02 -1.59 -1.14 Matched[5996]
YPR034W ARP7 Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation Verified chr16:639522-640955 639522-640955 98.4% 209.85 203.47 218.36 169.44 144.63 135.41 206.66 193.90 140.02 0.76 0.79 0.58 -0.47 -0.04 Matched[5997]
YPR035W GLN1 "Glutamine synthetase (GS), synthesizes glutamine from glutamate and ammonia; with Glt1p, forms the secondary pathway for glutamate biosynthesis from ammonia; expression regulated by nitrogen source and by amino acid limitation" Verified chr16:642205-643317 642205-643317 98.6% 8169.48 8533.94 8511.16 7839.64 1129.84 593.17 8351.71 8175.40 861.50 30.83 33.19 3.57 -3.25 -5.00 Matched[5999]
YPR036W VMA13 "Subunit H of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; serves as an activator or a structural stabilizer of the V-ATPase" Verified chr16:643833-645269 643833-645269 98.5% 1360.80 1755.55 1293.00 1398.93 1428.59 1389.75 1558.17 1345.97 1409.17 5.75 5.46 5.84 0.07 0.59 Frag>80[6000,6001,6002]
YPR036W-A Protein of unknown function; transcription is regulated by Pdr1p Verified chr16:645947-646150 645947-646150 99.1% 2779.88 5980.21 3160.76 2285.24 11258.04 7221.76 4380.05 2723.00 9239.90 16.17 11.05 38.28 1.76 NaN Matched[6003]
YPR038W Hypothetical protein; null mutant displays increased levels of spontaneous Rad52 foci Dubious chr16:646833-647192 646833-647192 99.3% 327.20 271.27 313.21 299.23 137.03 89.49 299.23 306.22 113.26 1.10 1.24 0.47 -1.43 -0.11 Frag<80[6004]
YPR039W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified non essential genes ERV2/YPR037C and TIP41/YPR040W" Dubious chr16:647009-647344 647009-647344 99.4% 104.80 125.76 122.77 77.85 74.86 47.91 115.28 100.31 61.38 0.43 0.41 0.25 -0.71 -0.49 Covered/w/another[6005]
YPR037C ERV2 "Flavin-linked sulfhydryl oxidase localized to the endoplasmic reticulum lumen, involved in disulfide bond formation within the ER" Verified chr16:646445-647035 646445-647035 98.8% 487.87 417.69 412.55 445.08 237.95 164.34 452.78 428.82 201.14 1.67 1.74 0.83 -1.09 -0.63 Matched[6004]
YPR040W TIP41 "Protein that interacts physically and genetically with Tap42p, which regulates protein phosphatase 2A; component of the TOR (target of rapamycin) signaling pathway" Verified chr16:647302-648372 647302-648372 98.7% 127.74 128.68 109.76 100.30 101.24 94.62 128.21 105.03 97.93 0.47 0.43 0.41 -0.10 0.31 Frag>80[6005]
YPR041W TIF5 Translation initiation factor eIF-5; N-terminal domain functions as a GTPase-activating protein to mediate hydrolysis of ribosome-bound GTP; C-terminal domain is the core of ribosomal preinitiation complex formation Verified chr16:648701-649918 648701-649918 98.6% 975.89 650.31 906.78 747.74 233.98 143.22 813.10 827.26 188.60 3.00 3.36 0.78 -2.13 -1.92 Matched[6006]
YPR042C PUF2 "Member of the PUF protein family, which is defined by the presence of Pumilio homology domains that confer RNA binding activity; preferentially binds mRNAs encoding membrane-associated proteins" Verified chr16:650432-653659 650432-653659 96.6% 86.87 90.40 75.97 82.38 133.67 173.10 88.63 79.18 153.38 0.33 0.32 0.64 0.95 1.46 Frag>80[6007]
YPR043W RPL43A "Protein component of the large (60S) ribosomal subunit, identical to Rpl43Bp and has similarity to rat L37a ribosomal protein; null mutation confers a dominant lethal phenotype" Verified chr16:654163-654844 654163-654164,654568-654844 85.4% 9863.59 8163.69 9066.11 7743.97 2980.06 2102.83 9013.64 8405.04 2541.45 33.27 34.12 10.53 -1.73 -2.15 Matched[6008]
YPR044C OPI11 "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene RPL43A/YPR043W; deletion confers sensitivity to GSAO" Dubious chr16:654521-654874 654521-654874 88.2% 8180.44 6751.90 7389.30 6389.96 2405.45 1732.82 7466.17 6889.63 2069.13 27.56 27.97 8.57 -1.74 -1.21 Matched[6008]
YPR045C Deletion mutant is synthetically lethal with MEN mutants Uncharacterized chr16:655137-656549 655137-656549 99.2% 179.10 190.52 158.41 166.97 295.41 226.19 184.81 162.69 260.80 0.68 0.66 1.08 0.68 0.39 Frag>80[6009,6010]
YPR046W MCM16 Protein involved in kinetochore-microtubule mediated chromosome segregation; binds to centromere DNA Verified chr16:656796-657341 656796-657341 98.8% 85.25 48.19 64.86 53.75 85.25 59.31 66.72 59.31 72.28 0.25 0.24 0.30 0.29 -0.15 Covered/w/another[6011]
YPR047W MSF1 "Mitochondrial phenylalanyl-tRNA synthetase alpha subunit, active as a monomer, unlike the cytoplasmic subunit which is active as a dimer complexed to a beta subunit dimer; similar to the alpha subunit of E. coli phenylalanyl-tRNA synthetase" Verified chr16:657526-658935 657526-658935 98.7% 108.48 163.80 138.66 148.72 226.31 168.83 136.14 143.69 197.57 0.50 0.58 0.82 0.46 0.56 Matched[6011]
YPR048W TAH18 "Protein with a potential role in DNA replication; displays synthetic lethal genetic interaction with the pol3-13 allele of POL3, which encodes DNA polymerase delta" Verified chr16:659179-661050 659179-661050 98.7% 69.78 56.80 65.46 47.06 18.93 13.52 63.29 56.26 16.23 0.23 0.23 0.07 -1.79 -1.09 Covered/w/another[6012]
YPR049C ATG11 Peripheral membrane protein required for delivery of aminopeptidase I (Lap4p) to the vacuole in the cytoplasm-to-vacuole targeting pathway; also required for peroxisomal degradation (pexophagy) Verified chr16:661134-664670 661134-664670 99.2% 38.75 40.46 28.20 22.79 41.88 32.19 39.60 25.50 37.04 0.15 0.10 0.15 0.54 0.72 Covered/w/another[6012]
YPR051W MAK3 Catalytic subunit of N-terminal acetyltransferase of the NatC type; required for replication of dsRNA virus Verified chr16:664957-665487 664957-665487 98.4% 354.21 298.68 310.17 181.89 269.96 97.65 326.45 246.03 183.81 1.21 1.00 0.76 -0.42 -1.09 Matched[6013]
YPR050C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene MAK3/YPR051W" Dubious chr16:664950-665363 664950-665363 98.4% 368.17 260.18 314.17 171.81 267.54 78.54 314.17 242.99 173.04 1.16 0.99 0.72 -0.49 -0.21 Matched[6013]
YPR052C NHP6A "High-mobility group non-histone chromatin protein, functionally redundant with Nhp6Bp; homologous to mammalian high mobility group proteins 1 and 2; acts to recruit transcription factor Rcs1p to certain promoters" Verified chr16:665690-665971 665690-665971 99.0% 2368.82 2039.12 2221.89 2024.79 1928.03 971.18 2203.97 2123.34 1449.60 8.14 8.62 6.01 -0.55 -0.81 Matched[6014]
YPR053C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene NHP6A/YPR052C" Dubious chr16:665785-666240 665785-666240 98.5% 1182.08 957.24 1117.52 950.56 912.72 494.20 1069.66 1034.04 703.46 3.95 4.20 2.91 -0.56 0.66 Frag<80[6014]
YPR054W SMK1 Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p Verified chr16:666277-667443 666277-667443 98.8% 80.70 96.32 80.70 67.68 137.97 101.52 88.51 74.19 119.74 0.33 0.30 0.50 0.69 0.09 Matched[6015]
YPR055W SEC8 "Essential 121kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis" Verified chr16:667673-670870 667673-670870 99.1% 92.47 97.52 92.47 82.37 112.99 126.24 95.00 87.42 119.62 0.35 0.35 0.50 0.45 0.90 Matched[6016]
YPR056W TFB4 "Subunit of TFIIH complex, involved in transcription initiation, similar to 34 kDa subunit of human TFIIH; interacts with Ssl1p" Verified chr16:671123-672139 671123-672139 98.7% 183.22 181.23 168.28 132.44 146.38 53.77 182.23 150.36 100.07 0.67 0.61 0.41 -0.59 -1.41 Covered/w/another[6017]
YPR057W BRR1 "snRNP protein component of spliceosomal snRNPs, required for pre-mRNA splicing and snRNP biogenesis; in null mutant newly-synthesized snRNAs are destabilized and 3'-end processing is slowed" Verified chr16:672468-673493 672468-673493 98.6% 168.07 207.61 135.44 127.53 101.83 65.25 187.84 131.49 83.54 0.69 0.53 0.35 -0.65 -0.47 Covered/w/another[6017]
YPR058W YMC1 "Mitochondrial protein, putative inner membrane transporter with a role in oleate metabolism and glutamate biosynthesis; member of the mitochondrial carrier (MCF) family; has similarity with Ymc2p" Verified chr16:673748-674671 673748-674671 98.7% 172.11 195.13 169.92 138.13 61.39 35.08 183.62 154.02 48.23 0.68 0.63 0.20 -1.67 -1.24 Matched[6018]
YPR059C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YMC1/YPR058W" Dubious chr16:674311-674697 674311-674697 98.9% 232.43 198.48 198.48 190.64 80.96 57.45 215.45 194.56 69.21 0.80 0.79 0.29 -1.49 -0.96 Matched[6018]
YPR060C ARO7 "Chorismate mutase, catalyzes the conversion of chorismate to prephenate to initiate the tyrosine/phenylalanine-specific branch of aromatic amino acid biosynthesis" Verified chr16:674858-675628 674858-675628 99.0% 286.77 206.90 257.97 208.21 179.40 167.61 246.84 233.09 173.51 0.91 0.95 0.72 -0.43 -0.07 Matched[6019]
YPR061C JID1 "Probable Hsp40p co-chaperone, has a DnaJ-like domain and appears to be involved in ER-associated degradation of misfolded proteins containing a tightly folded cytoplasmic domain; inhibits replication of Brome mosaic virus in S. cerevisiae" Verified chr16:675974-676879 675974-676879 99.2% 37.84 34.50 32.28 31.16 70.12 60.10 36.17 31.72 65.11 0.13 0.13 0.27 1.04 0.67 Matched[6020]
YPR062W FCY1 "Cytosine deaminase, zinc metalloenzyme that catalyzes the hydrolytic deamination of cytosine to uracil; of biomedical interest because it also catalyzes the deamination of 5-fluorocytosine (5FC) to form anticancer drug 5-fluorouracil (5FU)" Verified chr16:677162-677638 677162-677638 98.3% 1433.85 1158.61 1175.68 1173.54 1147.94 940.97 1296.23 1174.61 1044.45 4.78 4.77 4.33 -0.17 -0.10 Matched[6021]
YPR063C ER-localized protein of unknown function Uncharacterized chr16:677809-678317 677809-678190,678277-678317 98.4% 689.35 747.00 742.19 617.29 720.58 542.83 718.17 679.74 631.71 2.65 2.76 2.62 -0.11 -0.13 Covered/w/another[6022]
YPR064W "Dubious open reading frame, unlikely to encode a functional protein; based on available experimental and comparative sequence data" Dubious chr16:678948-679367 678948-679367 98.5% 12.09 14.50 7.25 4.83 24.17 33.84 13.29 6.04 29.01 0.05 0.02 0.12 2.26 -0.14 Covered/w/another[6022]
YPR065W ROX1 Heme-dependent repressor of hypoxic genes; contains an HMG domain that is responsible for DNA bending activity Verified chr16:679690-680796 679690-680796 98.9% 313.40 255.83 334.41 370.96 198.27 211.06 284.62 352.69 204.67 1.05 1.43 0.85 -0.79 -0.26 Covered/w/another[6022]
YPR066W UBA3 "Protein that acts together with Ula1p to activate Rub1p before its conjugation to proteins (neddylation), which may play a role in protein degradation; GFP-fusion protein localizes to the cytoplasm in a punctate pattern" Verified chr16:681210-682109 681210-682109 98.8% 55.12 78.74 46.12 51.74 95.61 70.86 66.93 48.93 83.24 0.25 0.20 0.34 0.77 0.78 Covered/w/another[6022]
YPR067W ISA2 "Protein required for maturation of mitochondrial and cytosolic Fe/S proteins, localizes to the mitochondrial intermembrane space, overexpression of ISA2 suppresses grx5 mutations" Verified chr16:682217-682774 682217-682774 98.9% 186.65 270.01 230.14 242.83 255.51 193.90 228.33 236.48 224.71 0.84 0.96 0.93 -0.07 0.25 Covered/w/another[6022]
YPR068C HOS1 "Putative class I histone deacetylase (HDAC) with sequence similarity to Hda1p, Rpd3p, Hos2p, and Hos3p; deletion results in increased histone acetylation at rDNA repeats; interacts with the Tup1p-Ssn6p corepressor complex" Verified chr16:682938-684350 682938-684350 99.2% 62.79 59.22 55.65 47.80 46.38 29.25 61.00 51.73 37.82 0.23 0.21 0.16 -0.45 -0.77 Covered/w/another[6022]
YPR069C SPE3 "Spermidine synthase, involved in biosynthesis of spermidine and also in biosynthesis of pantothenic acid; spermidine is required for growth of wild-type cells" Verified chr16:684553-685434 684553-685434 99.0% 830.11 607.99 776.30 704.16 782.02 659.51 719.05 740.23 720.77 2.65 3.00 2.99 -0.04 0.33 Matched[6023]
YPR070W MED1 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation Verified chr16:685895-687595 685895-687595 99.0% 127.70 132.45 103.94 98.59 84.34 73.65 130.07 101.27 78.99 0.48 0.41 0.33 -0.36 -0.21 Matched[6024]
YPR071W Putative membrane protein; YPR071W is not an essential gene Uncharacterized chr16:688169-688804 688169-688804 98.6% 122.74 146.65 132.31 97.24 119.55 102.02 134.70 114.77 110.79 0.50 0.47 0.46 -0.05 0.18 Matched[6025]
YPR072W NOT5 "Subunit of the CCR4-NOT complex, which is a global transcriptional regulator with roles in transcription initiation and elongation and in mRNA degradation" Verified chr16:690104-691786 690104-691786 98.7% 355.06 318.35 332.79 321.36 391.16 293.67 336.70 327.07 342.42 1.24 1.33 1.42 0.07 0.62 Covered/w/another[6026]
YPR073C LTP1 Protein phosphotyrosine phosphatase of unknown cellular role; activated by adenine Verified chr16:691930-692415 691930-692415 99.4% 480.25 459.55 471.97 397.45 894.26 494.74 469.90 434.71 694.50 1.73 1.76 2.88 0.68 0.09 Covered/w/another[6026]
YPR074C TKL1 "Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids" Verified chr16:692793-694835 692793-694835 98.7% 1976.68 1495.41 2016.87 1847.18 745.22 1002.73 1736.05 1932.03 873.98 6.41 7.84 3.62 -1.14 -0.79 Covered/w/another[6026]
YPR074W-A Hypothetical protein identified by homology Dubious chr16:695015-695185 695015-695185 98.1% 0.00 5.96 0.00 0.00 0.00 0.00 2.98 0.00 0.00 0.01 0.00 0.00 NaN 0.09
YPR076W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr16:696473-696847 696473-696847 98.7% 175.68 197.30 213.51 156.76 216.22 235.14 186.49 185.14 225.68 0.69 0.75 0.94 0.29 0.36 Matched[6028]
YPR075C OPY2 Integral membrane protein that functions in the signaling branch of the high-osmolarity glycerol (HOG) pathway; interacts with Ste50p; overproduction blocks cell cycle arrest in the presence of mating pheromone Verified chr16:695734-696816 695734-696816 99.0% 256.56 262.16 269.62 239.77 300.41 304.14 259.36 254.69 302.27 0.96 1.03 1.25 0.25 0.61 Matched[6028]
YPR077C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; expression increased by deletion of NAP1" Dubious chr16:697128-697499 697128-697499 99.0% 8.15 10.87 5.43 2.72 21.73 40.75 9.51 4.07 31.24 0.04 0.02 0.13 2.94 1.40 Covered/w/another[6029]
YPR078C Putative protein of unknown function; possible role in DNA metabolism and/or in genome stability; expression is heat-inducible Uncharacterized chr16:697144-698262 697144-698262 99.2% 14.42 21.63 11.72 7.21 21.63 41.46 18.02 9.46 31.54 0.07 0.04 0.13 1.74 1.06 Matched[6029]
YPR079W MRL1 "Membrane protein with similarity to mammalian mannose-6-phosphate receptors, possibly functions as a sorting receptor in the delivery of vacuolar hydrolases" Verified chr16:698867-700012 698867-700012 98.7% 104.36 107.02 117.63 93.75 304.25 220.22 105.69 105.69 262.23 0.39 0.43 1.09 1.31 1.55 Matched[6030]
YPR080W TEF1 Translational elongation factor EF-1 alpha; also encoded by TEF2; functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes Verified chr16:700592-701968 700592-701968 2.6% 13674.74 9605.54 11128.03 9162.63 4346.02 2740.48 11640.14 10145.33 3543.25 42.97 41.18 14.68 -1.52 -1.90 Frag<80[6031,6032,6033]
YPR081C GRS2 "Protein with sequence similarity to Grs1p, which is a glycyl-tRNA synthetase; cannot substitute for Grs1p; possible pseudogene that is expressed at very low levels" Verified chr16:702112-703968 702112-703968 99.2% 73.26 112.34 79.23 80.86 137.30 129.70 92.80 80.05 133.50 0.34 0.32 0.55 0.74 0.29 Frag>80[6032,6033,6034,6035]
YPR082C DIB1 "17-kDa component of the U4/U6aU5 tri-snRNP, plays an essential role in pre-mRNA splicing, orthologue of hDIM1, the human U5-specific 15-kDa protein" Verified chr16:704223-704654 704223-704654 99.3% 249.34 261.00 202.74 230.70 167.78 153.80 255.17 216.72 160.79 0.94 0.88 0.67 -0.43 -0.53 Matched[6035]
YPR083W MDM36 Protein required for normal mitochondrial morphology and inheritance Verified chr16:704852-706591 704852-706591 98.9% 42.44 43.60 43.60 42.44 36.63 30.81 43.02 43.02 33.72 0.16 0.17 0.14 -0.35 0.17 Matched[6036]
YPR084W Putative protein of unknown function Uncharacterized chr16:706970-708340 706970-708340 98.8% 93.72 108.48 91.51 81.92 92.99 67.16 101.10 86.71 80.07 0.37 0.35 0.33 -0.11 0.34 Covered/w/another[6037]
YPR085C Putative protein of unknown function; YPR085C is an essential gene Uncharacterized chr16:708495-709826 708495-709826 99.3% 95.23 92.96 55.17 49.88 95.23 47.62 94.10 52.53 71.42 0.35 0.21 0.30 0.44 0.30 Covered/w/another[6037]
YPR086W SUA7 "Transcription factor TFIIB, a general transcription factor required for transcription initiation and start site selection by RNA polymerase II" Verified chr16:710099-711136 710099-711136 98.5% 355.87 358.81 335.34 293.30 256.15 237.58 357.34 314.32 246.86 1.32 1.28 1.02 -0.35 -0.06 Matched[6038]
YPR087W VPS69 "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 85% of ORF overlaps the verified gene SRP54; deletion causes a vacuolar protein sorting defect" Dubious chr16:711352-711672 711352-711672 99.3% 768.93 552.37 649.67 621.42 477.05 395.45 660.65 635.54 436.25 2.44 2.58 1.81 -0.54 -0.61 Covered/w/another[6039]
YPR088C SRP54 "Signal recognition particle (SRP) subunit (homolog of mammalian SRP54); contains the signal sequence-binding activity of SRP, interacts with the SRP RNA, and mediates binding of SRP to signal receptor; contains GTPase domain" Verified chr16:711401-713026 711401-713026 99.3% 515.37 457.14 472.63 459.62 306.62 292.99 486.26 466.12 299.81 1.79 1.89 1.24 -0.64 -0.18 Matched[6039]
YPR089W Protein of unknown function; exhibits genetic interaction with ERG11 and protein-protein interaction with Hsp82p Uncharacterized chr16:713273-715939 713273-715939 98.9% 172.46 133.80 155.79 131.91 95.52 91.73 153.13 143.85 93.62 0.57 0.58 0.39 -0.62 0.24 Matched[6040]
YPR092W "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr16:718377-718682 718377-718682 98.6% 56.35 53.03 36.46 39.77 33.14 59.66 54.69 38.12 46.40 0.20 0.15 0.19 0.28 0.75 Covered/w/another[6041]
YPR091C "Putative protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YPR091C is not an essential gene" Verified chr16:716154-718466 716154-718466 99.1% 136.56 175.39 175.39 170.15 255.67 236.47 155.97 172.77 246.07 0.58 0.70 1.02 0.51 0.92 Matched[6041]
YPR093C ASR1 Protein involved in a putative alcohol-responsive signaling pathway; accumulates in the nucleus under alcohol stress; contains a Ring/PHD finger domain Verified chr16:719556-720422 719556-720422 99.1% 46.57 57.04 46.57 51.22 146.68 101.28 51.80 48.89 123.98 0.19 0.20 0.51 1.34 1.47 Covered/w/another[6043]
YPR094W RDS3 Zinc cluster protein involved in pre-mRNA splicing and cycloheximide resistance Verified chr16:720635-720958 720635-720958 98.5% 103.45 122.26 128.53 84.64 313.48 150.47 112.85 106.58 231.97 0.42 0.43 0.96 1.12 0.39 Covered/w/another[6043]
YPR095C SYT1 Guanine nucleotide exchange factor (GEF) for Arf proteins; involved in vesicular transport; suppressor of ypt3 mutations; member of the Sec7-domain family Verified chr16:721035-724715 721035-724715 99.1% 71.00 83.89 66.62 61.13 52.09 60.31 77.44 63.87 56.20 0.29 0.26 0.23 -0.18 -0.28 Covered/w/another[6043]
YPR096C "Protein of unknown function that may interact with ribosomes, based on co-purification experiments" Verified chr16:724840-725142 724840-725142 98.9% 16.69 10.01 23.36 16.69 6.67 0.00 13.35 20.02 3.34 0.05 0.08 0.01 -2.58 0.07
YPR097W "Protein that contains a Phox homology (PX) domain and binds phosphoinositides; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" Verified chr16:725392-728613 725392-728613 98.8% 133.81 106.49 118.42 103.03 121.88 95.18 120.15 110.73 108.53 0.44 0.45 0.45 -0.03 0.21 Matched[6044]
YPR098C "Protein of unknown function, localized to the mitochondrial outer membrane" Verified chr16:728945-729526 728945-729383,729480-729526 98.9% 395.28 461.86 445.21 453.54 971.57 634.54 428.57 449.38 803.05 1.58 1.82 3.33 0.84 0.21 Matched[6045]
YPR100W MRPL51 Mitochondrial ribosomal protein of the large subunit Verified chr16:729789-730211 729789-730211 98.3% 716.56 656.45 591.52 598.74 868.05 625.19 686.50 595.13 746.62 2.53 2.42 3.09 0.33 -0.17 Matched[6046]
YPR099C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene MRPL51/YPR100W" Dubious chr16:729755-730111 729755-730111 98.3% 740.92 606.98 587.03 646.88 812.16 618.38 673.95 616.96 715.27 2.49 2.50 2.96 0.21 -0.04 Matched[6046]
YPR101W SNT309 "Component of NineTeen complex (NTC) containing Prp19p involved in mRNA splicing, interacts physically and genetically with Prp19p" Verified chr16:730490-731017 730490-731017 98.6% 140.18 203.55 176.67 147.86 186.27 151.70 171.87 162.27 168.99 0.63 0.66 0.70 0.06 -0.35 Matched[6047]
YPR102C RPL11A "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl11Bp; involved in ribosomal assembly; depletion causes degradation of proteins and RNA of the 60S subunit; has similarity to E. coli L5 and rat L11" Verified chr16:731222-731746 731222-731746 23.9% 7020.90 5460.70 6256.72 5357.21 1321.39 1209.95 6240.80 5806.97 1265.67 23.04 23.57 5.24 -2.20 -3.59 Frag<80[6048,6049]
YPR103W PRE2 "20S proteasome beta-type subunit, responsible for the chymotryptic activity of the proteasome" Verified chr16:732347-733210 732347-733210 98.8% 919.92 754.69 922.27 880.08 1451.95 991.41 837.30 901.17 1221.68 3.09 3.66 5.06 0.44 0.40 Matched[6050]
YPR104C FHL1 Transcriptional activator with similarity to DNA-binding domain of Drosophila forkhead but unable to bind DNA in vitro; required for rRNA processing; isolated as a suppressor of splicing factor prp4 Verified chr16:733621-736431 733621-736431 99.2% 138.39 108.64 86.05 81.03 49.12 43.74 123.52 83.54 46.43 0.46 0.34 0.19 -0.85 -0.45 Matched[6051]
YPR105C COG4 "Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" Verified chr16:736982-739567 736982-739567 99.3% 125.03 130.48 127.37 118.80 108.28 100.88 127.76 123.08 104.58 0.47 0.50 0.43 -0.24 0.30 Matched[6052]
YPR106W ISR1 "Predicted protein kinase, overexpression causes sensitivity to staurosporine, which is a potent inhibitor of protein kinase C" Verified chr16:740059-741390 740059-741390 99.1% 134.04 163.57 109.81 96.93 124.95 84.06 148.81 103.37 104.51 0.55 0.42 0.43 0.02 0.81 Matched[6053]
YPR107C YTH1 "Essential RNA-binding component of cleavage and polyadenylation factor, contains five zinc fingers; required for pre-mRNA 3'-end processing and polyadenylation" Verified chr16:741436-742062 741436-742062 99.1% 141.56 114.22 115.83 99.74 262.22 133.52 127.89 107.78 197.87 0.47 0.44 0.82 0.88 0.27 Covered/w/another[6053]
YPR108W RPN7 "Essential, non-ATPase regulatory subunit of the 26S proteasome, similar to another S. cerevisiae regulatory subunit, Rpn5p, as well as to mammalian proteasome subunits" Verified chr16:742452-743741 742452-743741 98.7% 542.47 427.07 579.37 508.72 1035.49 700.27 484.77 544.05 867.88 1.79 2.21 3.60 0.67 0.67 Matched[6054]
YPR108W-A Putative protein of unknown function; identified by fungal homology and RT-PCR Uncharacterized chr16:744173-744385 744173-744385 75.6% 0.00 6.21 0.00 0.00 31.06 6.21 3.11 0.00 18.63 0.01 0.00 0.08 Inf NaN Overlap[6055]
YPR109W Predicted membrane protein; dipoid deletion strain has high budding index Uncharacterized chr16:744687-745571 744687-745571 98.8% 177.33 162.46 168.18 116.69 265.42 148.73 169.89 142.43 207.07 0.63 0.58 0.86 0.54 0.18 Matched[6055]
YPR110C RPC40 "RNA polymerase subunit, common to RNA polymerase I and III" Verified chr16:745826-746833 745826-746833 99.1% 766.57 537.40 591.44 462.35 78.06 39.03 651.99 526.90 58.54 2.41 2.14 0.24 -3.17 -2.77 Frag>80[6056,6057]
YPR111W DBF20 "Ser/Thr kinase involved in late nuclear division, one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis" Verified chr16:747304-748998 747304-748998 98.7% 59.76 79.48 53.19 50.20 48.41 44.22 69.62 51.69 46.31 0.26 0.21 0.19 -0.16 0.23 Covered/w/another[6058]
YPR112C MRD1 "Essential conserved protein that associates with 35S precursor rRNA and is required for its initial processing at the A(0)-A(2) cleavage sites, shows partial nucleolar localization, contains five consensus RNA-binding domains" Verified chr16:749254-751917 749254-751917 99.3% 187.80 107.69 95.22 68.77 12.47 4.91 147.75 82.00 8.69 0.55 0.33 0.04 -3.24 -2.92 Covered/w/another[6058]
YPR113W PIS1 "Phosphatidylinositol synthase, required for biosynthesis of phosphatidylinositol, which is a precursor for polyphosphoinositides, sphingolipids, and glycolipid anchors for some of the plasma membrane proteins" Verified chr16:752255-752917 752255-752917 98.8% 1609.06 2076.20 1525.09 1506.77 1212.14 960.24 1842.63 1515.93 1086.19 6.80 6.15 4.50 -0.48 -0.37 Matched[6059]
YPR114W Putative protein of unknown function Uncharacterized chr16:753299-754246 753299-754246 99.1% 508.87 613.20 495.03 472.68 390.70 380.06 561.04 483.85 385.38 2.07 1.96 1.60 -0.33 -0.05 Matched[6060]
YPR115W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm Uncharacterized chr16:754875-758126 754875-758126 98.7% 182.86 246.72 211.83 198.75 165.41 168.53 214.79 205.29 166.97 0.79 0.83 0.69 -0.30 0.38 Matched[6061]
YPR116W Putative protein of unknown function Uncharacterized chr16:758646-759479 758646-759479 98.9% 4.85 7.28 8.49 4.85 8.49 18.19 6.06 6.67 13.34 0.02 0.03 0.06 1.00 1.16 Overlap[6062]
YPR117W Putative protein of unknown function Uncharacterized chr16:760023-767492 760023-767492 98.9% 57.37 67.24 42.21 37.21 31.52 55.20 62.31 39.71 43.36 0.23 0.16 0.18 0.13 0.17 Matched[6062]
YPR118W "Methylthioribose-1-phosphate isomerase, catalyzes the isomerization of 5-methylthioribose-1-phosphate to 5-methylthioribulose-1-phosphate in the methionine salvage pathway" Verified chr16:767750-768985 767750-768985 98.8% 375.73 220.20 326.61 318.43 148.98 75.31 297.96 322.52 112.15 1.10 1.31 0.46 -1.52 -1.87 Matched[6063]
YPR119W CLB2 "B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome" Verified chr16:771651-773126 771651-773126 98.7% 220.40 231.38 223.14 187.44 120.15 78.27 225.89 205.29 99.21 0.83 0.83 0.41 -1.05 -0.67 Matched[6065]
YPR120C CLB5 B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1 phase Verified chr16:773873-775180 773873-775180 98.6% 117.11 94.62 91.52 59.72 45.76 27.92 105.87 75.62 36.84 0.39 0.31 0.15 -1.04 -0.45 Frag>80[6066,6067]
YPR121W THI22 Protein with similarity to hydroxymethylpyrimidine phosphate kinases; member of a gene family with THI20 and THI21; not required for thiamine biosynthesis Verified chr16:778579-780297 778579-780297 98.4% 83.93 124.12 61.47 56.15 47.28 39.01 104.03 58.81 43.15 0.38 0.24 0.18 -0.45 0.39 Covered[6068]
YPR122W AXL1 Haploid specific endoprotease that performs one of two N-terminal cleavages during maturation of a-factor mating pheromone; required for axial budding pattern of haploid cells Verified chr16:782041-785667 782041-785667 99.0% 140.68 165.76 123.69 94.72 84.41 72.71 153.22 109.20 78.56 0.57 0.44 0.33 -0.48 -0.24 Matched[6069]
YPR124W CTR1 "High-affinity copper transporter of the plasma membrane, mediates nearly all copper uptake under low copper conditions; transcriptionally induced at low copper levels and degraded at high copper levels" Verified chr16:786204-787424 786204-787424 98.7% 486.37 120.35 464.79 294.65 673.12 353.58 303.36 379.72 513.35 1.12 1.54 2.13 0.44 1.01 Matched[6070]
YPR123C Hypothetical protein Dubious chr16:786137-786571 786137-786571 98.2% 299.74 74.93 346.57 248.22 426.19 222.46 187.34 297.39 324.32 0.69 1.21 1.34 0.13 -0.09 Covered/w/another[6070]
YPR125W YLH47 "Mitochondrial inner membrane protein exposed to the mitochondrial matrix, associates with mitochondrial ribosomes, NOT required for respiratory growth; homolog of human Letm1, a protein implicated in Wolf-Hirschhorn syndrome" Verified chr16:787957-789321 787957-789321 98.6% 164.23 147.14 139.71 133.02 101.07 83.97 155.68 136.36 92.52 0.57 0.55 0.38 -0.56 0.21 Frag>80[6071,6072]
YPR126C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr16:789073-789381 789073-789381 98.2% 237.33 220.85 194.48 151.63 145.04 141.74 229.09 173.05 143.39 0.85 0.70 0.59 -0.27 0.22 Matched[6072]
YPR127W Putative protein of unknown function; expression is activated by transcription factor YRM1/YOR172W; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus Uncharacterized chr16:790079-791116 790079-791116 98.6% 194.45 289.23 202.26 165.13 472.93 463.15 241.84 183.70 468.04 0.89 0.75 1.94 1.35 1.66 Matched[6073]
YPR128C ANT1 Peroxisomal adenine nucleotide transporter; involved in beta-oxidation of medium-chain fatty acid; required for peroxisome proliferation Verified chr16:791214-792200 791214-792200 98.9% 136.25 141.38 171.08 151.62 116.79 96.30 138.81 161.35 106.54 0.51 0.65 0.44 -0.60 0.15 Matched[6074]
YPR129W SCD6 "Protein containing an Lsm domain, may bind RNA and have a role in RNA processing; overproduction suppresses a null mutation in CHC1, which encodes the heavy chain of clathrin" Verified chr16:792683-793732 792683-793732 98.6% 496.34 446.13 522.41 500.20 477.99 377.56 471.23 511.31 427.78 1.74 2.08 1.77 -0.26 0.06 Matched[6075]
YPR130C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr16:793370-793777 793370-793777 98.7% 501.45 464.21 600.74 533.72 575.92 369.88 482.83 567.23 472.90 1.78 2.30 1.96 -0.26 -0.19 Matched[6075]
YPR131C NAT3 "Catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes acetylation of the amino-terminal methionine residues of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met" Verified chr16:793907-794494 793907-794494 99.3% 167.88 183.30 161.03 133.62 169.59 104.50 175.59 147.32 137.04 0.65 0.60 0.57 -0.10 0.12 Matched[6076]
YPR132W RPS23B "Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit, required for translational accuracy; nearly identical to Rps23Ap and similar to E. coli S12 and rat S23 ribosomal proteins; deletion of both RPS23A and RPS23B is lethal" Verified chr16:794961-795763 794961-795025,795391-795763 42.6% 10337.80 8729.22 9608.58 8042.90 2777.48 2756.03 9533.51 8825.74 2766.76 35.19 35.83 11.46 -1.67 -3.52 Matched[6077]
YPR133C SPN1 "Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II, probable transcriptional elongation factor; metazoan homologs contain an acidic N terminus; mutations in the gene confer an Spt- phenotype" Verified chr16:795974-797206 795974-797206 99.3% 336.43 350.31 356.84 360.93 300.50 201.69 343.37 358.89 251.10 1.27 1.46 1.04 -0.52 -0.33 Matched[6078]
YPR133W-A TOM5 Small mitochondrial outer membrane protein crucial to a binding relay for the import of proteins into mitochondria; subunit on the outer mouth of the TOM channel that accepts precursors from the receptors Tom20p and Tom22p Verified chr16:797553-797705 797553-797705 98.4% 1507.89 1162.47 1468.03 1361.75 1228.90 624.41 1335.18 1414.89 926.65 4.93 5.74 3.84 -0.61 -1.03 Matched[6079]
YPR134W MSS18 Nuclear encoded protein needed for efficient splicing of mitochondrial COX1 aI5beta intron; mss18 mutations block cleavage of 5' exon - intron junction; phenotype of intronless strain suggests additional functions Verified chr16:798047-798853 798047-798853 98.6% 109.35 115.64 105.58 100.56 106.84 60.33 112.50 103.07 83.59 0.42 0.42 0.35 -0.30 -0.06 Matched[6080]
YPR135W CTF4 "Chromatin-associated protein, required for sister chromatid cohesion; interacts with DNA polymerase alpha (Pol1p) and may link DNA synthesis to sister chromatid cohesion" Verified chr16:799230-802013 799230-802013 98.8% 103.66 88.02 102.56 88.74 62.92 52.01 95.84 95.65 57.46 0.35 0.39 0.24 -0.74 -0.34 Matched[6081]
YPR137W RRP9 "Protein involved in pre-rRNA processing, associated with U3 snRNP; component of small ribosomal subunit (SSU) processosome; ortholog of the human U3-55k protein" Verified chr16:802355-804076 802355-804076 98.4% 239.57 155.78 164.04 129.82 32.45 34.22 197.67 146.93 33.34 0.73 0.60 0.14 -2.14 -2.18 Matched[6082]
YPR136C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF RRP9" Dubious chr16:802321-802833 802321-802833 98.2% 172.75 137.01 119.14 109.21 15.88 51.63 154.88 114.17 33.76 0.57 0.46 0.14 -1.76 -0.86 Covered/w/another[6082]
YPR138C MEP3 Ammonium permease of high capacity and low affinity; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation ammonia permease Verified chr16:810980-812449 810980-812449 98.9% 295.12 314.39 260.04 200.88 300.63 216.70 304.76 230.46 258.66 1.12 0.94 1.07 0.17 0.35 Covered/w/another[6084]
YPR139C VPS66 Cytoplasmic protein of unknown function involved in vacuolar protein sorting. Verified chr16:813152-814054 813152-814054 99.1% 258.04 231.23 254.69 226.76 222.29 197.72 244.64 240.73 210.01 0.90 0.98 0.87 -0.20 0.03 Covered/w/another[6084]
YPR140W TAZ1 "Lyso-phosphatidylcholine acyltransferase, required for normal phospholipid content of mitochondrial membranes; may remodel acyl groups of cardiolipin in the inner membrane; similar to human tafazzin, which is implicated in Barth syndrome" Verified chr16:814387-815532 814387-815532 98.8% 168.62 142.13 181.86 177.44 323.11 244.54 155.37 179.65 283.82 0.57 0.73 1.18 0.66 0.67 Matched[6085]
YPR141C KAR3 "Minus-end-directed microtubule motor that functions in mitosis and meiosis, localizes to the spindle pole body and localization is dependent on functional Cik1p, required for nuclear fusion during mating; potential Cdc28p substrate" Verified chr16:815730-817919 815730-817919 99.4% 80.84 79.01 63.85 59.71 57.88 43.64 79.92 61.78 50.76 0.30 0.25 0.21 -0.28 -0.01 Matched[6086]
YPR143W RRP15 "Nucleolar protein, constituent of pre-60S ribosomal particles; required for processing of the 27S pre-rRNA at the A2 site to yield 5.8S and 25S rRNA" Verified chr16:818319-819071 818319-819071 97.9% 488.36 269.95 276.74 240.11 84.11 46.12 379.15 258.42 65.11 1.40 1.05 0.27 -1.99 -2.14 Matched[6087]
YPR142C Hypothetical protein; open reading frame overlaps 5' end of essential RRP15 gene required for ribosomal RNA processing Dubious chr16:818126-818689 818126-818689 98.0% 318.43 164.64 161.03 150.17 56.09 34.38 241.54 155.60 45.23 0.89 0.63 0.19 -1.78 -0.89 Frag<80[6087]
YPR144C NOC4 "Nucleolar protein, forms a complex with Nop14p that mediates maturation and nuclear export of 40S ribosomal subunits" Verified chr16:819761-821419 819761-821419 98.9% 193.74 130.38 101.74 84.68 18.28 20.10 162.06 93.21 19.19 0.60 0.38 0.08 -2.28 -3.25 Matched[6088]
YPR145W ASN1 "Asparagine synthetase, isozyme of Asn2p; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway" Verified chr16:822616-824334 822616-824334 90.6% 2747.87 2851.26 2248.90 2079.36 655.66 518.88 2799.56 2164.13 587.27 10.33 8.78 2.43 -1.88 -1.77 Matched[6091]
YPR145C-A Putative protein of unknown function Uncharacterized chr16:824686-824922 824686-824922 99.5% 4.24 4.24 0.00 8.48 21.21 21.21 4.24 4.24 21.21 0.02 0.02 0.09 2.32 NaN Matched[6092]
YPR146C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr16:825343-825672 825343-825672 99.2% 161.87 232.12 155.76 161.87 192.42 106.90 197.00 158.82 149.66 0.73 0.64 0.62 -0.09 -0.18 Frag<80[6093]
YPR147C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS Uncharacterized chr16:825641-826555 825641-826555 99.1% 208.48 238.27 195.25 188.63 207.38 129.06 223.38 191.94 168.22 0.82 0.78 0.70 -0.19 -0.08 Matched[6094]
YPR148C "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" Verified chr16:826829-828136 826829-828136 98.8% 454.26 444.97 406.28 440.33 578.08 441.11 449.62 423.31 509.59 1.66 1.72 2.11 0.27 0.27 Frag>80[6095,6096,6097]
YPR149W NCE102 Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycolipid-enriched complexes (DIGs) Verified chr16:829914-830435 829914-830435 99.1% 3906.57 5257.73 4992.91 4855.67 20128.22 15233.89 4582.15 4924.29 17681.06 16.91 19.99 73.26 1.84 1.17 Matched[6099]
YPR150W "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene SUE1/YPR151C" Dubious chr16:830995-831516 830995-831516 99.2% 15.45 15.45 25.10 21.24 249.11 133.25 15.45 23.17 191.18 0.06 0.09 0.79 3.04 0.87 Covered/w/another[6100]
YPR151C SUE1 Mitochondrial protein required for degradation of unstable forms of cytochrome c Verified chr16:831051-831671 831051-831671 99.2% 16.24 8.12 22.73 17.86 243.57 129.91 12.18 20.30 186.74 0.04 0.08 0.77 3.20 3.07 Covered/w/another[6100]
YPR152C "Pre-mRNA splicing factor associated with the U2-U5-U6 snRNPs, the RES complex, and the Prp19-associated complex (NTC); null mutation displays synthetic genetic interactions with mutations affecting U2 snRNA and pre-mRNA splicing factors" Uncharacterized chr16:832057-833454 832057-833454 99.1% 46.91 57.01 37.52 32.47 38.25 43.30 51.96 35.00 40.77 0.19 0.14 0.17 0.22 0.30 Covered/w/another[6100]
YPR153W Putative protein of unknown function Verified chr16:833685-834241 833685-833689,833824-834241 98.9% 50.18 74.08 57.35 43.02 64.52 38.24 62.13 50.18 51.38 0.23 0.20 0.21 0.03 -0.68 Matched[6101]
YPR154W PIN3 Protein that induces appearance of [PIN+] prion when overproduced Verified chr16:834561-835208 834561-835208 98.5% 285.12 469.97 324.28 332.11 2207.31 2537.86 377.55 328.20 2372.58 1.39 1.33 9.83 2.85 2.62 Frag>80[6102,6103]
YPR155C NCA2 Protein involved in regulation of mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p) of the Fo-F1 ATP synthase; functions with Nca3p Verified chr16:835559-837409 835559-837409 99.3% 71.31 81.10 87.09 101.25 149.15 101.79 76.21 94.17 125.47 0.28 0.38 0.52 0.41 0.43 Matched[6104]
YPR156C TPO3 Polyamine transport protein specific for spermine; localizes to the plasma membrane; member of the major facilitator superfamily Verified chr16:837905-839773 837905-839773 39.4% 233.52 257.96 176.50 135.77 134.41 126.27 245.74 156.14 130.34 0.91 0.63 0.54 -0.26 -0.04 Frag<80[6105,6106,6107]
YPR157W Putative protein of unknown function Uncharacterized chr16:841262-842665 841262-842665 98.5% 26.03 25.30 11.57 13.01 26.75 28.20 25.67 12.29 27.47 0.09 0.05 0.11 1.16 1.40 Frag<80[6108]
YPR158W Putative protein of unknown function Uncharacterized chr16:843258-844016 843258-844016 98.7% 73.39 77.39 116.08 89.40 1288.93 600.43 75.39 102.74 944.68 0.28 0.42 3.91 3.20 2.82 Matched[6109]
YPR159W KRE6 "Protein required for beta-1,6 glucan biosynthesis; putative beta-glucan synthase; appears functionally redundant with Skn1p" Verified chr16:857579-859741 857579-859741 98.1% 388.39 402.06 387.92 313.45 214.46 158.37 395.22 350.68 186.42 1.46 1.42 0.77 -0.91 -0.26 Matched[6115]
YPR159C-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Uncharacterized chr16:860310-860411 860310-860411 49.5% 39.64 0.00 0.00 19.82 138.73 19.82 19.82 9.91 79.27 0.07 0.04 0.33 3.00 NaN Matched[6116]
YPR160W GPH1 "Non-essential glycogen phosphorylase required for the mobilization of glycogen, activity is regulated by cyclic AMP-mediated phosphorylation, expression is regulated by stress-response elements and by the HOG MAP kinase pathway" Verified chr16:861302-864010 861302-864010 98.8% 359.91 1654.54 904.82 1198.21 4826.83 4248.29 1007.23 1051.51 4537.56 3.72 4.27 18.80 2.11 1.93 Matched[6117]
YPR160W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; identified by expression profiling and mass spectrometry" Dubious chr16:861930-862010 861930-862010 98.6% 187.79 863.85 475.74 713.61 1802.82 2679.19 525.82 594.68 2241.00 1.94 2.41 9.29 1.91 NaN Covered/w/another[6117]
YPR160C-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr16:862573-862857 862573-862857 98.9% 287.40 1245.42 741.57 1064.46 3487.88 3800.12 766.41 903.02 3644.00 2.83 3.67 15.10 2.01 NaN Covered/w/another[6117]
YPR161C SGV1 "Cyclin (Bur2p)-dependent protein kinase that functions in transcriptional regulation; phosphorylates the carboxy-terminal domain of Rpo21p, which is the largest subunit of RNA polymerase II; regulated by Cak1p" Verified chr16:864445-866418 864445-866418 99.1% 165.58 140.54 159.44 162.00 93.01 77.68 153.06 160.72 85.34 0.57 0.65 0.35 -0.91 -0.41 Matched[6118]
YPR162C ORC4 "Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing" Verified chr16:866711-868300 866711-868300 99.2% 91.33 90.70 79.92 70.40 84.36 87.53 91.01 75.16 85.94 0.34 0.31 0.36 0.19 0.62 Frag>80[6119,6120,6121]
YPR163C TIF3 "Translation initiation factor eIF-4B, has RNA annealing activity; contains an RNA recognition motif and binds to single-stranded RNA" Verified chr16:868641-869951 868641-869951 90.3% 2018.72 1339.06 1550.13 1543.38 253.29 200.94 1678.89 1546.75 227.12 6.20 6.28 0.94 -2.77 -2.60 Frag>80[6121,6122,6123]
YPR164W MMS1 Protein likely involved in protection against replication-dependent DNA damage; mutants are sensitive to methyl methanesulfonate (MMS); implicated in regulation of Ty1 transposition Verified chr16:870699-874922 870699-874922 99.0% 57.65 84.20 42.10 45.93 24.40 38.51 70.93 44.02 31.46 0.26 0.18 0.13 -0.48 0.15 Matched[6124]
YPR165W RHO1 "GTP-binding protein of the rho subfamily of Ras-like proteins, involved in establishment of cell polarity; regulates protein kinase C (Pkc1p) and the cell wall synthesizing enzyme 1,3-beta-glucan synthase (Fks1p and Gsc2p)" Verified chr16:875364-875993 875364-875993 98.4% 2492.27 2361.61 2521.31 2369.67 3335.93 1834.12 2426.94 2445.49 2585.02 8.96 9.93 10.71 0.08 -0.94 Matched[6125]
YPR166C MRP2 Mitochondrial ribosomal protein of the small subunit Verified chr16:876278-876625 876278-876625 99.4% 488.44 456.65 580.92 430.64 589.60 329.48 472.54 505.78 459.54 1.74 2.05 1.90 -0.14 -0.70 Matched[6126]
YPR167C MET16 "3'-phosphoadenylsulfate reductase, reduces 3'-phosphoadenylyl sulfate to adenosine-3',5'-bisphosphate and free sulfite using reduced thioredoxin as cosubstrate, involved in sulfate assimilation and methionine metabolism" Verified chr16:876843-877628 876843-877628 99.2% 64.14 132.13 64.14 57.73 71.84 35.92 98.13 60.93 53.88 0.36 0.25 0.22 -0.18 -0.27 Matched[6127]
YPR168W NUT2 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for transcriptional activation and has a role in basal transcription Verified chr16:878072-878545 878072-878545 98.7% 104.70 91.88 81.20 76.92 85.47 79.06 98.29 79.06 82.26 0.36 0.32 0.34 0.06 0.62 Covered/w/another[6128]
YPR169W JIP5 "Nucleolar protein of unknown function, exhibits a physical interaction with Bre1p" Uncharacterized chr16:878686-880164 878686-880164 98.6% 447.73 310.60 306.49 247.52 189.24 143.99 379.17 277.00 166.61 1.40 1.12 0.69 -0.73 -0.56 Covered/w/another[6128]
YPR169W-A "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps two other dubious ORFs: YPR170C and YPR170W-B" Dubious chr16:883235-883453 883235-883453 99.5% 1018.74 1073.80 936.14 945.32 899.43 660.80 1046.27 940.73 780.11 3.86 3.82 3.23 -0.27 NaN Matched[6129]
YPR170W-B "Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the dubious genes YPR169W-A, YPR170W-A and YRP170C" Dubious chr16:883235-883591 883235-883383,883483-883591 99.1% 1677.69 1853.67 1482.16 1380.48 1466.51 965.94 1765.68 1431.32 1216.23 6.52 5.81 5.04 -0.23 NaN Matched[6129]
YPR170C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORFs YPR169W-A and YPR170W-B" Dubious chr16:882979-883314 882979-883314 99.0% 565.41 514.29 526.32 442.11 511.28 312.78 539.85 484.21 412.03 1.99 1.97 1.71 -0.23 -0.37 Matched[6129]
YPR170W-A "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; identified by expression profiling and mass spectrometry" Dubious chr16:883374-883559 883374-883559 99.5% 707.63 885.89 599.59 567.18 648.21 421.34 796.76 583.39 534.77 2.94 2.37 2.22 -0.13 NaN Matched[6129]
YPR171W BSP1 Adapter that links synaptojanins Inp52p and Inp53p to the cortical actin cytoskeleton Verified chr16:883824-885554 883824-885554 98.8% 146.16 130.38 112.84 126.29 109.33 87.11 138.27 119.56 98.22 0.51 0.49 0.41 -0.28 0.08 Matched[6130]
YPR172W "Protein of unknown function, transcriptionally activated by Yrm1p along with genes involved in multidrug resistance" Uncharacterized chr16:885792-886394 885792-886394 98.8% 204.71 273.51 201.36 219.81 437.95 337.27 239.11 210.59 387.61 0.88 0.85 1.61 0.88 0.84 Matched[6131]
YPR173C VPS4 AAA-type ATPase that is regulated by Vta1p; required for late endosome to vacuole transport; catalyzes the release of an endosomal membrane-associated class E VPS protein complex; regulates cellular sterol metabolism Verified chr16:886520-887833 886520-887833 99.3% 667.09 673.99 535.97 504.54 673.99 583.51 670.54 520.26 628.75 2.48 2.11 2.61 0.27 0.41 Covered/w/another[6132]
YPR174C Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery; potential Cdc28p substrate Uncharacterized chr16:888039-888704 888039-888704 98.7% 212.95 159.72 146.03 98.87 147.55 167.32 186.34 122.45 157.43 0.69 0.50 0.65 0.36 0.61 Covered/w/another[6132]
YPR175W DPB2 "Second largest subunit of DNA polymerase II (DNA polymerase epsilon), required for normal yeast chromosomal replication; expression peaks at the G1/S phase boundary; potential Cdc28p substrate" Verified chr16:888970-891039 888970-891039 98.9% 74.77 65.00 72.81 43.00 60.60 44.47 69.88 57.91 52.53 0.26 0.24 0.22 -0.14 0.19 Matched[6133]
YPR176C BET2 Beta subunit of Type II geranylgeranyltransferase required for vesicular transport between the endoplasmic reticulum and the Golgi; provides a membrane attachment moiety to Rab-like proteins Ypt1p and Sec4p Verified chr16:891097-892074 891097-892074 99.0% 173.50 187.96 178.67 142.52 186.93 109.47 180.73 160.59 148.20 0.67 0.65 0.61 -0.12 -0.35 Matched[6134]
YPR178W PRP4 "Splicing factor, component of the U4/U6-U5 snRNP complex" Verified chr16:892328-893725 892328-893725 98.5% 68.99 69.72 75.53 49.38 75.53 46.48 69.35 62.45 61.00 0.26 0.25 0.25 -0.03 0.44 Matched[6135]
YPR177C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the 5' end of the essential PRP4 gene encoding a component of the U4/U6-U5 snRNP complex" Dubious chr16:892309-892680 892309-892680 98.4% 62.84 40.98 43.72 27.32 57.38 27.32 51.91 35.52 42.35 0.19 0.14 0.18 0.25 0.04 Covered/w/another[6135]
YPR179C HDA3 Subunit of a possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex that contains an Hda1p homodimer and an Hda2p-Hda3p heterodimer; required for the activity of the complex; has similarity to Hda2p Verified chr16:893793-895760 893793-895760 99.3% 96.19 104.37 84.93 77.26 102.33 56.28 100.28 81.09 79.30 0.37 0.33 0.33 -0.03 0.08 Matched[6136]
YPR180W AOS1 "Nuclear protein that acts as a heterodimer with Uba2p to activate Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability" Verified chr16:895957-897000 895957-897000 98.6% 184.56 185.53 163.19 192.33 346.78 228.28 185.05 177.76 287.53 0.68 0.72 1.19 0.69 0.79 Matched[6137]
YPR181C SEC23 "GTPase-activating protein; component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat, involved in ER to Golgi transport and autophagy; stimulates the GDP-bound form of Sar1p" Verified chr16:897357-899663 897357-899663 98.6% 573.04 526.86 621.86 575.24 509.27 565.12 549.95 598.55 537.20 2.03 2.43 2.23 -0.16 0.39 Matched[6138]
YPR182W SMX3 "Core Sm protein Sm F; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Sme1p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm F" Verified chr16:900190-900450 900190-900450 98.3% 183.27 304.14 261.25 237.86 382.13 148.17 243.70 249.55 265.15 0.90 1.01 1.10 0.09 0.27 Matched[6139]
YPR183W DPM1 "Dolichol phosphate mannose (Dol-P-Man) synthase of the ER membrane, catalyzes the formation of Dol-P-Man from Dol-P and GDP-Man; required for glycosyl phosphatidylinositol membrane anchoring, O mannosylation, and protein glycosylation" Verified chr16:900751-901554 900751-901554 98.5% 1147.24 1151.03 1187.63 1142.20 814.05 757.26 1149.14 1164.91 785.65 4.24 4.73 3.26 -0.57 -0.19 Matched[6140]
YPR184W GDB1 "Glycogen debranching enzyme containing glucanotranferase and alpha-1,6-amyloglucosidase activities, required for glycogen degradation; phosphorylated in mitochondria" Verified chr16:902040-906650 902040-906650 98.7% 83.91 246.90 161.23 202.75 477.11 679.43 165.41 181.99 578.27 0.61 0.74 2.40 1.67 2.07 Frag>80[6141,6142]
YPR185W ATG13 "Phosphorylated protein that interacts with Vac8p, required for the cytoplasm-to-vacuole targeting (Cvt) pathway and autophagy" Verified chr16:907214-909430 907214-909430 98.6% 187.10 268.53 191.68 192.14 245.66 210.89 227.82 191.91 228.28 0.84 0.78 0.95 0.25 0.29 Matched[6143]
YPR186C PZF1 "Transcription factor IIIA (TFIIIA), essential protein with nine C2H2 Zn-fingers, binds the 5S rRNA gene through the zinc finger domain and directs assembly of a multiprotein initiation complex for RNA polymerase III; also binds DNA" Verified chr16:909729-911018 909729-911018 99.3% 71.79 73.35 61.65 49.16 53.06 36.68 72.57 55.40 44.87 0.27 0.22 0.19 -0.30 -0.31 Matched[6144]
YPR187W RPO26 "RNA polymerase subunit ABC23, common to RNA polymerases I, II, and III; part of central core; similar to bacterial omega subunit" Verified chr16:911253-911796 911253-911272,911349-911796 98.5% 1270.69 943.26 1049.51 917.24 318.76 219.01 1106.98 983.38 268.88 4.09 3.99 1.11 -1.87 -1.97 Matched[6145]
YPR188C MLC2 "Regulatory light chain for the type II myosin, Myo1p; binds to an IQ motif of Myo1p, localization to the bud neck depends on Myo1p; involved in the disassembly of the Myo1p ring" Verified chr16:911984-912475 911984-912475 99.3% 278.24 263.92 235.27 233.23 503.28 368.26 271.08 234.25 435.77 1.00 0.95 1.81 0.90 0.68 Matched[6146]
YPR189W SKI3 Protein involved in exosome mediated 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs; forms complex with Ski2p and Ski8p; required for repressing propagation of dsRNA viruses Verified chr16:912660-916958 912660-916958 98.6% 100.54 106.92 88.98 95.35 63.25 71.75 103.73 92.17 67.50 0.38 0.37 0.28 -0.45 -0.25 Matched[6147]
YPR190C RPC82 RNA polymerase III subunit C82 Verified chr16:917073-919037 917073-919037 99.2% 142.64 121.60 99.54 103.64 13.85 9.24 132.12 101.59 11.54 0.49 0.41 0.05 -3.14 -1.90 Matched[6148]
YPR191W QCR2 "Subunit 2 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; phosphorylated; transcription is regulated by Hap1p, Hap2p/Hap3p, and heme" Verified chr16:919377-920483 919377-920483 98.7% 598.63 718.54 800.00 970.25 1182.61 1097.48 658.58 885.13 1140.05 2.43 3.59 4.72 0.37 0.57 Matched[6149]
YPR192W AQY1 "Spore-specific water channel that mediates the transport of water across cell membranes, developmentally controlled; may play a role in spore maturation, probably by allowing water outflow, may be involved in freeze tolerance" Verified chr16:921856-922773 921856-922773 98.5% 37.59 50.85 42.01 26.53 84.02 72.96 44.22 34.27 78.49 0.16 0.14 0.33 1.20 1.12 Matched[6151]
YPR193C HPA2 "Tetrameric histone acetyltransferase with similarity to Gcn5p, Hat1p, Elp3p, and Hpa3p; acetylates histones H3 and H4 in vitro and exhibits autoacetylation activity" Verified chr16:922905-923375 922905-923375 99.2% 32.12 25.69 6.42 17.13 32.12 25.69 28.91 11.78 28.91 0.11 0.05 0.12 1.30 1.17 Covered/w/another[6151]
YPR194C OPT2 "Oligopeptide transporter; member of the OPT family, with potential orthologs in S. pombe and C. albicans" Verified chr16:924300-926933 924300-926933 99.1% 98.09 141.01 111.12 94.26 78.17 63.99 119.55 102.69 71.08 0.44 0.42 0.29 -0.53 -0.63 Matched[6153]
YPR195C "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" Dubious chr16:927961-928290 927961-928290 98.9% 49.04 76.62 49.04 58.23 42.91 12.26 62.83 53.63 27.58 0.23 0.22 0.11 -0.96 -0.52 Matched[6154]
YPR196W Putative maltose activator Uncharacterized chr16:931372-932784 931372-932784 88.0% 40.22 58.73 27.35 15.29 31.37 13.68 49.48 21.32 22.53 0.18 0.09 0.09 0.08 0.64 Frag<80[6156]
YPR198W SGE1 "Plasma membrane multidrug transporter of the major facilitator superfamily, acts as an extrusion permease; partial multicopy suppressor of gal11 mutations" Verified chr16:934030-935661 934030-935661 99.1% 163.18 182.34 136.60 126.09 110.02 63.05 172.76 131.35 86.53 0.64 0.53 0.36 -0.60 -0.31 Matched[6157]
YPR197C "Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data" Dubious chr16:933894-934457 933894-934457 99.0% 89.58 91.37 80.62 57.33 68.08 44.79 90.47 68.98 56.43 0.33 0.28 0.23 -0.29 -0.43 Covered/w/another[6157]
YPR199C ARR1 "Transcriptional activator of the bZIP family, required for transcription of genes involved in resistance to arsenic compounds" Verified chr16:938144-939028 938144-939028 99.2% 153.85 218.80 148.15 162.96 221.08 151.57 186.32 155.56 186.32 0.69 0.63 0.77 0.26 0.38 Matched[6159]
YPR200C ARR2 Arsenate reductase required for arsenate resistance; converts arsenate to arsenite which can then be exported from cells by Arr3p Verified chr16:939275-939667 939275-939667 99.2% 66.67 28.21 38.47 48.72 64.11 58.98 47.44 43.59 61.55 0.18 0.18 0.26 0.50 -0.01 Covered/w/another[6160]
YPR201W ARR3 "Arsenite transporter of the plasma membrane, required for resistance to arsenic compounds; transcription is activated by Arr1p in the presence of arsenite" Verified chr16:939918-941132 939918-941132 99.1% 21.60 20.77 14.13 10.80 38.22 39.05 21.19 12.46 38.64 0.08 0.05 0.16 1.63 1.34 Covered/w/another[6160]
YPR202W Putative protein of unknown function with similarity to telomere-encoded helicases; YPR202W is not an essential gene; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo Uncharacterized chr16:943028-943892 943028-943046,943195-943892 0.6% 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 NaN -0.18
YPR203W Putative protein of unknown function Uncharacterized chr16:943876-944184 943876-944184 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN -0.15
YPR204W Helicase-like protein encoded within the telomeric Y' element Uncharacterized chr16:944599-947697 944599-947697 0.0% Inf Inf NaN NaN NaN NaN Inf NaN NaN Inf NaN NaN NaN 0.20
YPR204C-A "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" Dubious chr16:946852-947334 946852-947334 0.0% NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN