- Supplemental Figure 1a and 1b - Supplemental figure.1a. Genetic and environmental contributions to leptin-BMI association in 218 male adolescent twin pairs adjusted with age, and tanner stages.
AE model was the best-fitting model for the bivariate analyses of BMI and leptin in males; rG, and rE denoted genetic, and unique environmental correlations, respectively; a2 and e2 denoted percentage of total phenotypic variance accounted for genetic factors, and unique environmental factors; rTP, total phenotypic correlation; CGCP, Genetic contribution to total phenotypic correlation; CUCP, unique environmental contribution to total phenotypic correlation. Supplemental figure.1b. Genetic and environmental contributions to leptin-BMI association in 243 female adolescent twin pairs adjusted with age, and tanner stages.
AE model was the best-fitting model for the bivariate analyses of BMI and leptin in females; rG, and rE denoted genetic, and unique environmental correlations, respectively; a2 and e2 denoted percentage of total phenotypic variance accounted for genetic factors, and unique environmental factors; rTP, total phenotypic correlation; CGCP, Genetic contribution to total phenotypic correlation; CUCP, unique environmental contribution to total phenotypic correlation.
- Supplemental Figure 2a and 2b - Supplemental figure.2a. Genetic and environmental contributions to leptin-FMI association in 218 male adolescent twin pairs adjusted with age, and tanner stages.
AE model was the best-fitting model for the bivariate analyses of FMI and leptin in males; rG, and rE denoted genetic, and unique environmental correlations, respectively; a>2 and e2 denoted percentage of total phenotypic variance accounted for genetic factors, and unique environmental factors; rTP, total phenotypic correlation; CGCP, Genetic contribution to total phenotypic correlation; CUCP, unique environmental contribution to total phenotypic correlation. Supplemental figure.2b. Genetic and environmental contributions to leptin-FMI association in 243 female adolescent twin pairs adjusted with age, and tanner stages.
AE model was the best-fitting model for the bivariate analyses of FMI and leptin in females; rG, and rE denoted genetic, and unique environmental correlations, respectively; a2 and e2 denoted percentage of total phenotypic variance accounted for genetic factors, and unique environmental factors; rTP, total phenotypic correlation; CGCP, Genetic contribution to total phenotypic correlation; CUCP, unique environmental contribution to total phenotypic correlation.
- Supplemental Figure 3a and 3b - Supplemental figure.3a. Genetic and environmental contributions to leptin-WC association in 218 male adolescent twin pairs adjusted with age, and tanner stages.
AE model was the best-fitting model for the bivariate analyses of WC and leptin in males; rG, and rE denoted genetic, and unique environmental correlations, respectively; a2 and e2> denoted percentage of total phenotypic variance accounted for genetic factors, and unique environmental factors; rTP, total phenotypic correlation; CGCP, Genetic contribution to total phenotypic correlation; CUCP, unique environmental contribution to total phenotypic correlation. Supplemental figure.3b. Genetic and environmental contributions to leptin-WC association in 243 female adolescent twin pairs adjusted with age, and tanner stages.
AE model was the best-fitting model for the bivariate analyses of WC and leptin in females; rG, and rE denoted genetic, and unique environmental correlations, respectively; a2 and e2 denoted percentage of total phenotypic variance accounted for genetic factors, and unique environmental factors; rTP, total phenotypic correlation; CGCP, Genetic contribution to total phenotypic correlation; CUCP, unique environmental contribution to total phenotypic correlation.
- Supplemental Figure 4a and 4b - Supplemental figure.4a. Genetic and environmental contributions to leptin-%TF association in 218 male adolescent twin pairs adjusted with age, and tanner stages.
None common environmental correlation model was the best-fitting model for the bivariate analyses of %TF and leptin in males; rG and rE denoted genetic, common, and unique environmental correlations, respectively; a2, c2 and e2 denoted percentage of total phenotypic variance accounted for genetic factors, common environmental, and unique environmental factors; rTP, total phenotypic correlation; CGCP, Genetic contribution to total phenotypic correlation; CUCP, unique environmental contribution to total phenotypic correlation. Supplemental figure.4b. Genetic and environmental contributions to leptin-%TF association in 243 female adolescent twin pairs adjusted with age, and tanner stages. AE model was the best-fitting model for the bivariate analyses of %TFI and leptin in females; rG and rE denoted genetic, and unique environmental correlations, respectively; a2 and e2 denoted percentage of total phenotypic variance accounted for genetic factors, and unique environmental factors; rTP, total phenotypic correlation; CGCP, Genetic contribution to total phenotypic correlation; CUCP, unique environmental contribution to total phenotypic correlation.