Table 1 Characteristics of the individual trials
Trial | Allocation concealment | Participants Major diagnostic category | Day Hospital Treatment | Comparison Treatment | Numbers at recruitment &Nos followed up DH V Alternative | Follow up |
Woodford-Williams Sunderland (1962) n=331 | Uncertain "reference to random number tables" | Contactable patients from a consecutive series of 500 former inpatients discharged to live alone. Patients >60 years. Not psychiatric | Attendance x 1 a week up to one year | Eligible, but not referred to usual services. | 168 V 163 168 V 163 | 12 months |
Weissert USA (1980) n=644 | Not reported | Referrals from many sources. Eligible for Medicare. Need rehabilitation 70% moderately or severely disabled. 41% of pts. with circulatory disorders | New service. Average of 70 days attendance over one year. | Eligible, but not referred to usual services. | 322 V 322 Death and poor outcome: V 239 (n=384) Institutionalisation 194 V 190 ADL (survivors): 169 V 151 | 12 months Some outcome data available only for a subgroup of 384 patients |
Tucker Auckland (1984) n=120 | Uncertain "reference to random number tables" | Referrals from hospital & GPs >55 years Patients need assessment & rehabilitation. Excluded:Dementia, needing social care. 54% of pts. with stroke Baseline Northwick Park ADL score mean (range) 17.6 (12-31) and 16.3 (12-25) | New service. Attendance 2/3 days week for 6-8 weeks. | Comprehensive elderly care (Inpatient, outpatient follow-up with or without outpatient physiotherapy, domiciliary services,GP, day centre). | 62 V 58 Death: 62 V 57 Institutionalisation 59 V 50 | 5 months |
Cummings New York (1985) n=96 | Not reported | Patients referred for inpatient rehabilitation: >15 years Disabled (not Spinal injuries or head injury). Living with someone, fit to travel, telephone, suitable residence, Medicare eligible 57% of pts. with stroke Baseline Kenny ADL index 21.8 and 22.1 | New service Attendance 5 days a week Mean attendance 69 days. | Continuing rehabilitation in hospital. | 48 V 48 Death: 48 V 48 Poor outcome: 42 V 45 | 3 months after discharge from treatment |
Vetter Cardiff (1989) n=59 | Concealed allocation | Consecutive patients attending two day hospitals eligible if: Need rehabilitation Not attended day hospital in previous year. Did not require medical investigations. Not confused. Randomised after first assessment visit to day hospital. 22% of pts with stroke Baseline Barthel Index @ 13 (median) | Attendance for eight weeks | New service Home rehabilitation by therapy team. Attempt to equalise amount of treatment given. | 29 V 30 Death & institutionalisation 29 V 30 ADL: 27 V 30 | 8 weeks |
Pitkala Helsinki, (1991) n=174 | Not concealed randomised by date of birth | Patients receiving home-care in a rural community in Finland. 30% pts. With arthritis 19% pts. with moderate/severe dementia | New service. Attendance over two months for a total of 20 visits. | Usual elderly care: home support + hospital care if necessary. | 88 V 86 Death & institutionalisation 88 V 86 ADL: 75 V 74 | 12 months |
Eagle Ontario, (1991) n=113 | Not reported | Hospital and community referrals >65 years Rehabilitation potential. 28% of pts with depression Baseline Geriatric Qualtiy of Life Questionnaire (ADL) mean 4.49 and 4.46 | Attendance 2 days a week. | Usual elderly care; (inpatient, or outpatient clinic or community follow up). Same staff treated both groups. | 55 V 58 55 V 58 | 12 months |
Young Bradford, (1992) n=124 | Concealed allocation | Patients discharged home from hospital after new stroke event. Fit to travel. >60 years, Barthel Index <20 Excluded: Patients discharged to residential/nursing home. Patients who needed to attend day hospital for respite (n=9) Baseline Barthel Index median(range) 15 (4-19) and 16 (1-19) | Attendance 2 days a week for at least 8 weeks. | Home physiotherapy to a maximum of 20 hours over the first 8 weeks. | 61 V 63 Death & institutionalisation 61 V 63 ADL: 52 V 56 | 6 months |
Hedrick USA, (1993) n=826 | Concealed allocation. | Eligible for Veterans Service & one of the following: 1 Living in a nursing home 2 Needed help for ADL activities. 3 Bowel incontinence 4 Significant cognitive impairment 5 Acceptable to day care staff 21% with diseases of the nervous system Baseline Sickness Impact Profile (Physical) mean (SD) 31.7 (18.8) and 33.8 (18.4) | Attendance 2/3 times a week. Average of 45 visits in 12 months. | Customary care (nursing home, inpatient care, clinic visits, home care etc.) | 411 V 415 Death & institutionalisation 395 V 390 | 12 months |
Gladman Nottingham, (1993) n=155 (Health Care of the Elderly stratum only) | Concealed allocation | Patients discharged home from hospital after new stroke event. Excluded: Discharged to residential/nursing home. Requiring respite or terminal care. Receiving outpatient rehabilitation prior to the stroke. No significant disability In hospital <7 days Baseline Barthel Index median (IQR) 17 (14-17) and 16 (13-17) | Routine hospital based services if considered appropriate, outpatient physiotherapy, OT, day hospital attendance etc. 37% (n=28) attended day hospital. | New service Domiciliary rehabilitation team 2 half-time physiotherapists 1 OT. 75% allocated patients received treatment. | 76 V 79 Death & institutionalisation 76 V 79 ADL: 73 V 67 | 12 months (hospital bed use & disability reported at 6 months) |
Hui Hong Kong (1995) n=120 | Concealed allocation | Patients admitted to a rehabilitation ward one week after acute stroke. Excluded: <65 years, previous stroke, dementia, Barthel Index =20 Baseline Barthel Index mean (SD) 9.9 (4.9) and 10.4 (5.3) | Care under geriatrician led team with day hospital follow up after discharge. | Same ward but care led by neurology team with medical outpatient follow up. | 59 V 61 Death & institutionalisation 49 V 50 ADL: 43 V 44 | 6 months |
Borland Huntingdon (1997) n=105 | Concealed allocation | Patients referred to day hospital Excluded: Patients with dysphasia If the multidisciplinary team recommended that the patients required nursing, Occupational Therapy >2 x week 22% of pts with stroke Baseline Barthel Index median (IQR) 15 (12-17) and 15 (11-17) | Multidisciplinary rehabilitation Median of 16 attendances | Rehabilitation at a day centre provided by a physiotherapist and two support workers, available two days a week. Median of 10 attendances. | 50 V 55 Death and institutionalisation 50 V 55 ADL: 19 V 25 | 12 months |