Table w1 Taxonomy of generic questions
 
 
 

Identification No
Categories
Generic type
No of questions (% of total of 1101)
Primary
Secondary
Tertiary
Quaternary
1.1.1.1
Epidemiology
Prevalence or incidence
 
 
 What is the incidence or prevalence of condition X? or

Why is the incidence or prevalence changing?

12 (1.1)
1.2.1.1
Epidemiology
Risk factors
 
 
 Is X a risk factor for Y?
4 (0.4)
1.3.1.1
Epidemiology
Course or prognosis
 
 
What is the usual course of disease or condition X? or

What is the prognosis of disease or condition X?

15 (1.4)
2.1.1.1
Diagnosis
Cause of clinical finding
Symptom
 
What is the cause of symptom X?
94 (8.5)
2.1.2.1
Diagnosis
Cause of clinical finding
Sign
 
What is the cause of physical finding X?
72 (6.5)
2.1.3.1
Diagnosis
Cause of clinical finding
Test finding (lab, ECG, imaging)
 
What is the cause of test finding X? or

How should I interpret test finding X?

45 (4.1)
2.1.4.1
Diagnosis
Cause of clinical finding
Unspecified findings or multiple categories of findings
 
Could this patient have disease or condition X? or

What does this patient have?

42 (3.8)
2.1.5.1
Diagnosis
Cause of clinical finding
Inconsistencies
 
Why were this patient's findings (or disease course) inconsistent with usual expectations?
13 (1.2)
2.2.1.1
Diagnosis
Test (lab, skin test, biopsy, imaging)
Indications
 
Is test X indicated in situation Y? or 

What test is indicated in situation Y?

41 (3.7)
2.2.2.1
Diagnosis
Test (lab, skin test, biopsy, imaging)
Timing
 
When (in terms of timing) should I do test X?
5 (0.5)
2.2.3.1
Diagnosis
Test (lab, skin test, biopsy, imaging)
Performance
 
How good is test X? or 

How good is test X in situation Y?

12 (1.1)
2.2.4.1
Diagnosis
Test (lab, skin test, biopsy, imaging)
Preparation
 
What is the preparation for test X?
2 (0.2)
2.2.5.1
Diagnosis
Test (lab, skin test, biopsy, imaging)
Normal values
 
 What are the normal values for test X?
5 (0.5)
2.3.1.1
Diagnosis
Name finding
Body part (anatomy) on physical exam or imaging study
 
What is the name of this body part? or 

What is the anatomy here?

8 (0.7)
2.3.2.1
Diagnosis
Name finding
Disease
 
What is the name of that disease?
5 (0.5)
2.3.3.1
Diagnosis
Name finding
Test
 
What is the name of that test?
2 (0.2)
2.4.1.1
Diagnosis
Disease criteria
 
 
What are the criteria for diagnosis of disease or condition X? or 

How do I diagnose condition X?

6 (0.5)
3.1.1.1
Treatment
Drug prescribing
Name finding
 
What is the name of that drug that I'm trying to think of?
10 (0.9)
3.1.2.1
Treatment
Drug prescribing
Dosage
 
 What is the dose of drug X?
88 (8.0)
3.1.3.1
Treatment
Drug prescribing
Physical characteristics
 
 What are the physical characteristics (dosage forms, tablet or liquid characteristics, container characteristics) of drug X?
28 (2.5)
3.1.4.1
Treatment
Drug prescribing
When (or how) to start or stop
 
 When (or how) should I start or stop drug X?
19 (1.7)
3.1.5.1
Treatment
Drug prescribing
Adverse effects
Findings caused by drug
Could finding Y be caused by drug X? or 

Does drug X cause finding Y?

31 (2.8)
3.1.5.2
Treatment
Drug prescribing
Adverse effects
What dose causes toxicity
What dose of drug X would cause toxicity?
1 (0.1)
3.1.5.3
Treatment
Drug prescribing
Adverse effects
Adverse effects of drug
What are the adverse effects of drug X?
5 (0.5)
3.1.5.4
Treatment
Drug prescribing
Adverse effects
Safety (includes safety in pregnancy and breast feeding)
Is drug X safe to use in situation Y?
19 (1.7)
3.1.5.5
Treatment
Drug prescribing
Adverse effects
Drug with fewest adverse effects
Which drug has the fewest adverse effects?
3 (0.3)
3.1.6.1
Treatment
Drug prescribing
Interactions
 
 Is it OK to use drug X with drug Y? or 

Are there any interactions between drug X and drug (or food) Y?

21 (1.9)
3.1.7.1
Treatment
Drug prescribing
Indications
 
 Is drug X indicated in situation Y? or 

Is any drug indicated in situation Y?

36 (3.3)
3.1.8.1
Treatment
Drug prescribing
Contraindications
 
 Is drug X contraindicated in situation Y?
2 (0.2)
3.1.9.1
Treatment
Drug prescribing
Pharmacodynamics or absorption
 
 What are the pharmacodynamics or absorption characteristics of drug X?
3 (0.3)
3.1.10.1
Treatment
Drug prescribing
Drug of choice
 
 What is the drug of choice for condition X or in situation Y?
36 (3.3)
3.1.11.1
Treatment
Drug prescribing
Efficacy
 
 Does drug X work for condition Y?
21 (1.9)
3.1.12.1
Treatment
Drug prescribing
Cost
Third party considerations
What drug can I use in situation Y, given third party rules Y?
2 (0.2)
3.1.12.2
Treatment
Drug prescribing
Cost
Cost comparison
Is drug X cheaper than drug Y?
4 (0.4)
3.1.12.3
Treatment
Drug prescribing
Cost
What is cost
What is the cost of drug X?
2 (0.2)
3.1.13.1
Treatment
Drug prescribing
Serum levels
 
What are the indications for getting a drug level or what time to draw or how often to draw?
3 (0.3)
3.1.14.1
Treatment
Drug prescribing
Orientation, help with recognition
 
What is drug X?
16 (1.5)
3.1.15.1
Treatment
Drug prescribing
Composition
 
What is in drug X? or 

How much of component X is in drug Y?

10 (0.9)
3.2.1.1
Treatment
Not limited to drug prescribing
Procedures
How to do it
How do you do procedure X?
3 (0.3)
3.2.1.2
Treatment
Not limited to drug prescribing
Procedures
Efficacy
What is the efficacy of procedure X? or 

Does procedure X work in situation Y?

5 (0.5)
3.2.2.1
Treatment
Not limited to drug prescribing
Principles of therapy
 
What are the principles behind therapy X?
2 (0.2)
3.2.3.1
Treatment
Not limited to drug prescribing
Treatment for disease or condition
 
How should I treat finding or disease X? or 

Should I use treatment Y for condition X?

75 (6.8)
3.2.4.1
Treatment
Not limited to drug prescribing
Practices of other physicians
 
Why did physician X treat the patient this way? or

How do other physicians manage condition X?

11 (1.0)
4.1.1.1
Management not limited to treatment
Disease or finding or situation
 
 
How should I manage disease or finding or situation X? (Not specifying diagnostic or therapeutic management)
78 (7.1)
4.2.1.1
Management not limited to treatment
Aggressive or conservative
 
 
 How aggressive or conservative should I be in situation X?
17 (1.5)
4.3.1.1
Management not limited to treatment
Compliance
 
 
 How can I get the patient or family to comply with my recommendations or agree with my assessment?
18 (1.6)
4.4.1.1
Management not limited to treatment
Referral
 
 
 When do you refer is situation X?
6 (0.5)
4.5.1.1
Management not limited to treatment
Patient education
 
 
 What patient education materials are available for situation X?
3 (0.3)
4.6.1.1
Management not limited to treatment
Support or community groups
 
 
 Is there a support group or community group for condition X?
2 (0.2)
4.7.1.1
Management not limited to treatment
Advise patient or family
 
 
 How should I advise the patient or family in situation X?
10 (0.9)
4.8.1.1
Management not limited to treatment
Monitoring
 
 
 When (timing) should I do test X to monitor disease or condition Y?
11 (1.0)
5.1.1.1
Prevention
Diagnostic screening test
Indications
 
 Should this kind of patient have screening test X? or 

What screening tests should this patient have?

10 (0.9)
5.1.2.1
Prevention
Diagnostic screening test
Timing
 
 When (timing) or how often should screening test X be done?
9 (0.8)
5.1.3.1
Prevention
Diagnostic screening test
Efficacy
 
 What is the efficacy of screening test X?
2 (0.2)
5.2.1.1
Prevention
Healthcare workers
 
 
 Is situation X dangerous for health care workers?
3 (0.3)
5.3.1.1
Prevention
Indications for prophylactic treatment
 
 
 Should this kind of patient get prophylactic treatment X to prevent disease Y? or 

What prophylactic treatment should I give to prevent disease Y?

16 (1.5)
6.1.1.1
Ethics
Financial
 
 
 Should I charge the patient in situation X?
1 (0.1)
6.2.1.1
Ethics
Conflict of interest
 
 
 Is this situation a conflict of interest?
2 (0.2)
7.1.1.1
Physician-patient communication
 
 
 
 What is the best way to discuss or approach discussion of difficult issue X?
4 (0.4)
8.1.1.1
Etiology
Cause of condition
 
 
 Why did the patient get disease or condition X?
4 (0.4)
8.2.1.1
Etiology
Role of disease agent
 
 
 Can finding or disease agent X cause disease Y? or 

What are the causes of disease or condition Y?

17 (1.5)
8.3.1.1
Etiology
Pathogenesis or mechanism
 
 
 How does disease X cause finding Y? or 

Can disease X cause finding Y?

11 (1.0)
8.4.1.1
Etiology
Genetics
 
 
Is disease or condition X hereditary?
2 (0.2)
9.1.1.1
Measurement unit conversion
 
 
 
 How do I convert from X units to Y units?
1 (0.1)
10.1.1.1
Education
Medical students or residents
 
 
 How can I better teach this learner (resident, medical student)?
1 (0.1)
10.2.1.1
Education
Continuing medical education
 
 
I need to learn more about topic X.
10 (0.9)
10.3.1.1
Education
Information source
 
 
 Where can I find information about topic X?
2 (0.2)
11.1.1.1
Frustration
 
 
 
 Generic type varies, not a true clinical question, rather an expression of frustration or an unanswerable dilemma
17 (1.5)
12.1.1.1
Unclassified
 
 
 
 Generic type varies, unable to classify.
5 (0.5)