Characterization of Novel Phosphodiesterases in the Bovine Ovarian Follicle

Supplemental Data

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  • Supplemental Figure S1 - "Cyclic AMP-PDE activity during in vitro maturation. Total cAMP-PDE activity was measured in COC (A, B), COC-cultured denuded oocytes (C, D), and COC-cultured cumulus cells (E, F), at various time points during the initial hours of meiotic resumption. PDE activity was measured in presence of cilostamide (10 µM; A, E), rolipram (10 µM; B, D, F) or IBMX (1 mM; C). The data presented are a mean ± SEM of at least three replicates."