>Ap-ago1a
VFNCPRRPNLGREGRPIVLRANHFQISMPRGYVHHYDINIQPDKCPRKVNREIIETMVHA
Y-SKLFGNLRPVFDGRNNLYTRDPLPIGNDRMELEVTLPGEGKDRVFRVNIKWLAQVSLF
ALEEALEGRTRQIPYDAILALDVVMRHLPSMTYTPVGRSFFSSPEGYYHPLGGGREVWFG
FHQSVRPSQWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRDIGEQR--KPLTDSQRVKFT
KEIKGLKIEITHCGAMRRKYRVCNVTRRPAQMQSFPLQLENGQTVECTVAKYFLDKYKMK
LRYPHLPCLQVGQEHKHTYLPLEVCNIVAGQRCIKKLTDMQTSTMIKATARSAPDREREI
NSLVRRADFNNDSYVQEFGLTISNSMMEVRGRVLPPPKLQYGGRTLPNQ-----GLNVQQ
TKQQALP----------NQGVWDMRGKQFFTGVEIRNWAIACFAPQR-------------
-TVREDALRNFTTQLQKISSDAGMPIVGQPCFCKYATGPDQVEPMFRYLKSTFTGLQLVV
VVLPGKTPVYAEVKRVGDTVLGMATQCVQAKNVNKTSPQTLSNLCLKINVKLGGINSILV
PSIRPKVFNEPVIFLGADVTHPPAGDNKKPSIAAVVGSMDAHPSRYAATVRVQQHRQ---
------------------------EIIQELSSMVRELLIMFYKSTGGYKPHRIILYRDGV
SEGQFPH-VLQHELTAIREACIKLEGDYKPGITFIIVQKRHHTRLFCADKKEQSGKSGNI
PAGTTVDVGITHPTEFDFYLCSHQGIQGTSRPSHYHVLWDDNHFESDELQCLTYQLCHTY
VRCTRSVSIPAPAYYAHLVAFRARYHLVEKEHDSGEGSHQSGCSE---DRTPGAMARAIT
VHADTKKVMYFA
>Ap-ago1b
VFNHPCRPNLGREGRPIRLRTNHFQVSMPRSYIQHYVIYIKPENCPRRVNREIIKIMVNA
Y-SKLFGNLRPAFDGRQNLYTRDPLPIGRKQVELEVKLPGQCKDGVFHVYIKWLAQISLF
DLEEALQGSRRPIPYDAVLALDVVMRHLASMTYTSVGKSFFSPPESYYHPLGGGREVWYG
FHQSMQPSKWKMMLNLDVSASAFYKSQLVPEFMCEVLDIKDISEQK--KPLTDSQRVKFT
REIKGLKIEITHWGEMRRKYKVRNVTRKPAQTQTFPLQEKN-NVVECTVAKYFLDKHNMK
LRYPNLPCLHVGEKHNHIYLPLEVCKIVKSQRCARKLTDMQTSTMIKETVRSAPAREQDI
NSLVRQADFKNNPYVKEFGLTVSDSMIELRGRVLPPPKLQYGGQTLPNQK----ILNAQQ
TKQQTLP----------SHGVWDMRGKQFFIGVKITNWAIACFASQF-------------
-SVRDDAIKNFTEQLQRISNEAGMPIVDAPCYCKYVTGLDQVEPMFNYLIKKFTKLQLII
VILPGKTPIYAEVKRVGDTVLGMATQCVQAKNVNKLSIQALSNLCLKINVKLGGTNTILV
PSVRPKVFNEPLIILGADITHATSNDDKISSIAAIVGSMDAHPSRYAAMVRIQQHRQ---
------------------------EFIQELSSMVRELLIMFYKSTRGYKPHRIILYRDGV
SEGQLSN-VFNYELMAIREACIKLEGGYKPGITFISVQKRHHTRLFCTDKTEQCGKSGNI
PAGTTVDIGITHPTEFDFYLCSHQGIQGTSRPSHYHVLWDDNNFKSDELQRLTYQLCYTY
VRCTRSISIPAPAYYAHLVAQRAKYHMVEKEHDSSEGSHISGCSE---DQTVDELARAIT
VHPNANKVMYFA
>Am-ago1
MFSCPRRPNIGREGRPIVLRANHFQITMPRGYVHHYDINIQPDKCPRKVNREIIETMVHA
Y-TKIFGTLKPVFDGRNNLYTRDPLPIGTDKIELEVTLPGEGKDRVFRVVIKWLAQVSLF
ALEEALEGRTRQIPYDAILALDVVMRHLPSMTYTPVGRSFFSTPDGYYHPLGGGREVWFG
FHQSVRPSQWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRDIGDQK--RPLTDSQRVKFT
KEIKGLKIEITHCGTMRRKYRVCNVTRKPAQMQSFPLQLENGQTVECTVAKYFLDKYKMK
LRHPYLPCLQVGQEHKHTYLPLEVCNIVAGQRCIKKLTDMQTSTMIKATARSAPDREREI
NNLVRRADFNNDSYVQEFGLTISNNMMEVRGRVLPPPKLQYGGR----------------
TKQQAIP----------NGGVWDMRGKQFFTGVEIRVWAIACFAPQR-------------
-TVRDDAIRNFIAQLQRISNDAGMPIIGQPCFCKYATGPDQVEPMFRYLKATFSSLQLVC
VILPGKTPVYAEVKRVGDTLLGMATQCVQAKNVNKTSPQTLSNLCLKINVKLGGINSILV
PTIRPKVFDEPVIFFGADVTHPPAGDNKKPSIAAVVASMDAHPSRYAATVRVQQHRQ---
------------------------EIIQELSSMVRELLLMFYKSTGGYKPLRIILYRDGV
SEGQFLH-VLQHELTAIREACIKLEAEYRPGITFVVVQKRHHTRLFCSEKRDQSGKSGNI
PAGTTVDVCITHPTEFDFYLCSHQGIQGTSRPSHYHVLWDDNRFESDELQSLTYQLCHTY
VRCTRSVSIPAPAYYAHLVAFRARYHLVEKEHDSGEGSHQSGCSE---DRTPGAMARAIT
VHANTKRVMYFA
>Dm-ago1
VFTCPRRPNLGREGRPIVLRANHFQVTMPRGYVHHYDINIQPDKCPRKVNREIIETMVHA
Y-SKIFGVLKPVFDGRNNLYTRDPLPIGNERLELEVTLPGEGKDRIFRVTIKWQAQVSLF
NLEEALEGRTRQIPYDAILALDVVMRHLPSMTYTPVGRSFFSSPEGYYHPLGGGREVWFG
FHQSVRPSQWKMMLNIDVSATAFYKAQPVIDFMCEVLDIRDINEQR--KPLTDSQRVKFT
KEIKGLKIEITHCGQMRRKYRVCNVTRRPAQMQSFPLQLENGQTVECTVAKYFLDKYRMK
LRYPHLPCLQVGQEHKHTYLPLEVCNIVAGQRCIKKLTDMQTSTMIKATARSAPDREREI
NNLVKRADFNNDSYVQEFGLTISNSMMEVRGRVLPPPKLQYGGR-----------VSTGL
TGQQLFPPQNKVSLASPNQGVWDMRGKQFFTGVEIRIWAIACFAPQR-------------
-TVREDALRNFTQQLQKISNDAGMPIIGQPCFCKYATGPDQVEPMFRYLKITFPGLQLVV
VVLPGKTPVYAEVKRVGDTVLGMATQCVQAKNVNKTSPQTLSNLCLKINVKLGGINSILV
PSIRPKVFNEPVIFLGADVTHPPAGDNKKPSIAAVVGSMDAHPSRYAATVRVQQHRQ---
------------------------EIIQELSSMVRELLIMFYKSTGGYKPHRIILYRDGV
SEGQFPH-VLQHELTAIREACIKLEPEYRPGITFIVVQKRHHTRLFCAEKKEQSGKSGNI
PAGTTVDVGITHPTEFDFYLCSHQGIQGTSRPSHYHVLWDDNHFDSDELQCLTYQLCHTY
VRCTRSVSIPAPAYYAHLVAFRARYHLVEKEHDSGEGSHQSGCSE---DRTPGAMARAIT
VHADTKKVMYFA
>Tc-ago1
VFQCPRRPNLGREGRPIGLKANHFQVTMPRGFVHHYDVSIQPDKCPRKVNREIIETMVHA
Y-GKIFGNLKPVFDGRNNLYTRDPLPIGNSREELEVTLPGEGKDRLFRVTIKWVAQVSLY
GLEEALEGRTRQIPYEAILALDVVMRHLPSMSYTPVGRSFFSSPEGYYHPLGGGREVWFG
FHQSVRPSQWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRDINEQR--KPLTDSQRVKFT
KEIKGLKIEITHCGTMRRKYRVCNVTRRPAQMQSFPLQLDNGQTVECTVAKYFLDKYKMK
LRYPHLPCLQVGQEHKHTYLPLEVCNIVAGQRCIKKLTDMQTSTMIKATARSAPDREREI
NNLVRRADFNNDPYVQEFGLTISNNMMEVRGRVLPPPKLQYGGR-----------VAS-L
SGQQAMP----------NQGVWDMRGKQFFTGVEIRVWAIACFAPQR-------------
-TVREDALRNFTQQLQKISNDAGMPIIGQPCFCKYATGPDQVEPMFRYLKSTFQSLQLVV
VVLPGKTPVYAEVKRVGDTVLGMATQCVQAKNVNKTSPQTLSNLCLKINVKLGGINSILV
PSIRPKIFNEPVIFLGADVTHPPAGDNKKPSIAAVVGSMDAHPSRYAATVRVQQHRQ---
------------------------EIIQELSSMVRELLIMFYKSTGGYKPHRIILYRDGV
SEGQFLQ-LLQHELTAIREACIKLESDYKPGITFIVVQKRHHTRLFCADKKEQSGKSGNI
PAGTTVDVGITHPTEFDFYLCSHQGIQGTSRPSHYHVLWDDSHLDSDELQCLTYQLCHTY
VRCTRSVSIPAPAYYAHLVAFRARYHLVEKEHDSGEGSHQSGSSE---DRTPGAMARAIT
VHADTKKVMYFA
>Ph-ago1
MFCCPRRPSLGREGRPIALRANHFQISMPRGYVHHYDINIQPDKCPRKVNREIIETMVHA
Y-SKIFGSLKPVFDGRQNLYTRDPLPIGNDRVELEVTLPGEGKDRVFRVTIKWVAQVSLF
ALEEALEGRTRQIPFDTILALDVVMRHLPSMTYTPVGRSFFSSPDGYYHPLGGGREVWFG
FHQSVRPSQWKMMLNIDVSATAFYKAQPVIDFMCEVLDIREINEQR--KTLTDSQRVKFT
KEIKGLKIEITHCGTMRRKYRVCNVTRRPAHMQSFPLQLENGQTVECTVAKYFLDKYKMK
LKYAHLPCLQVGQEHKHTYLPLEVCNIVAGQRCIKKLTDMQTSTMIKATARSAPDREKEI
NSLVRRADFNNDAYVQEFGLTISNNMMEVRGRVLPPPKLQYGGRSSLLSSDEFAIRNSFH
AKQQAMP----------IGGVWDMRGKQFFSGIEIRVWAIACFAPQR-------------
-TVKDDAVRAFIQQLQRISNDAGMPIVGQPCFCKYATGPDQVEPMFRYLKSSFHALQLVV
VVLPGKTPVYAEVKRVGDTLLGMATQCVQAKNVIKTSPQTLSNLCLKINVKLGGINSILV
PSIRPKVFNEPVIFLGADVTHPPAGDNKKPSIAAVVGSMDGHPSRYAATVRVQQHRQ---
------------------------EIIQELSSMVRELLLMFYKSTGGYKPHRIIMYRDGV
SEGQFLHVVLQHELTAVREACIQLEGDYKPGITFIVVQKRHHTRLFCADKKEQSGKSGNI
PAGTTVDVGITHPTEFDFYLCSHQGIQGTSRPSHYHVLWDDNRFDSDELQCLTYQLCHTY
VRCTRSVSIPAPAYYAHLVAFRARYHLVEKEHDSAEGSHQSSCSE---DRTPGAMARAIT
VHPETKKVMYFA
>Pm-ago1
AFVAPRRPNLGREGRPITLRANHFQISMPRGYIHHYDISITPDKCPRKVNREIIETMVHA
F-PRIFGTLKPVFDGRSNLYTRDPLPIGNEKMELEVTLPGEGRDRVFKVAMKWLAQVNLY
TLEEALEGRTRTIPYDAIQALDVVMRHLPSMTYTPVGRSFFSAPDGYYHPLGGGREVWFG
FHQSVRPSQWKMMLNIDVSATAFYKAQAVIEFMCEVLDIREIGEQR--KPLTDSQRVKFT
KEIKGLKIEITHCGAMRRKYRVCNVTRRPAQMQSFPLQLENGQTVECTVAKYFLDKYKMK
LRFPHLPCLQVGQEHKHTYLPLEVCNIVPGQRCIKKLTDMQTSTMIKATARSAPDREREI
NNLVRKADFNNDPYMQEFGLTISTAMMEVRGRVLPPPKLQYGGR----------------
TKQQALP----------NQGVWDMRGKQFFTGVEIRVWAVACFAPQR-------------
-TVREDALRNFTQQLQKISNDAGMPIIGQPCFCKYANGPDQVEPMFRYLKSTFTGLQLVC
VVLPGKTPVYAEVKRVGDTVLGMATQCVQAKNVNKTSPQTLSNLCLKINVKLGGINSILV
PGIRPKVFNEPVIFLGADVTHPPAGDNKKPSIAAVVGSMDAHPSRYAATVRVQQHRQNGS
TTQGQSASDGSRPRQLTFARTAHDEVIQELSSMVKELLIQFYKSTR-FKPNRIILYRDGV
SEGQFQT-VLQHELTAMREACIKLEADYKPGITYIAVQKRHHTRLFCSDKKEQSGKSGNI
PAGTTVDVGITHPTEFDFYLCSHQGIQGTSRPSHYHVLWDDNHFDSDELQCLTYQLCHTY
VRCTRSVSIPAPAYYAHLVAFRARYHLVEKEHDSGEGSHQSGNSE---DRTPSAMARAVT
VHVDTNRVMYFA
>Is-ago1
MFVCPRRPNVGTEGRPILLRANHFQISMPRGYLHHYDVTITPDKCPRKVNREIIETMVQS
Y-SKIFGQQKPVFDGRKNMYTRDDIPIGKDKAELEVTLPGEGKDRVFRVAIKWVAQVSLY
ALEEVLEGRSRHIPMDAVQALDVVMRHLPSMTYTPVGRSFFSSPDGYFHPLGGGREVWFG
FHQSVRPSQWKMMLNIDVSATAFYKAQPVTEFMCEVLELRDINEQR--KPLTDSQRVKFT
KEIKGLKIEITHCGTMRRKYRVCNVTRRPAQLQSFPLQLENGQTVECTVAKYFLDKYKMK
LRYPHLPCLQVGQEHKHTYLPLEVCNIVAGQRCIKKLTDMQTSTMIKATARSAPDREREI
NNLVRKADFNTDPYVQEFGLSISNTMMEVRGRILPPPKLQYGGR----------------
TKQQAIP----------NQGVWDMRGKQFHTGVEIRIWAIACFAPQRTSASGAIACFAPQ
RTCREDALRNFTQQLQKISNDAGMPIIGQPCFCKYATGPDQVEPMFRYLKSTFQGLQLVV
VVLPGKTPVYAEVKRVGDTVLGMATQCVQAKNVNKTSPQTLSNLCLKINVKLGGINSILV
PSIRPKVFNEPVIFLGADVTHPPAGDNKKPSIAAVVGSMDAHPSRYAATVRVQQHRQ---
------------------------EIIQDLASMVKELLIQFYKSTR-FKPNRIIFYRDGV
SEGQFQQ-VLHHELLAVREACMKLEADYKPGITFVVVQKRHHTRLFCSDKKEQIGKSGNI
PAGTTVDLGITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNQFSADELQCLTYQLCHTY
VRCTRSVSIPAPAYYAHLVAFRARYHLVEKEHDSGEGSHQSSNGD---DRTVVALARAVT
IHPETLKVMYFA
>Ci-ago
DFQAPPRPNQGQVGKPIWLKANYFKVSIPNGDIHHYDIDIKPDKCPRRVNREIINTMVEN
FRSAIFQDRKPVFDGRKNLYTAQPLPIDKQKLEVEVTLPGEGRDRTFTVAIKWASRVSLY
SLKLALEGKMHGIPFETVQSLDVVMRHLPSLRYTPVGRSFFSAPEGYTPPLGGGREVWFG
FHQSMRPSQWKMMLNIDVSATAFYRAQSCVQFLCDVLELR-IEDLRLIRGLTDSQRVKFT
KEIRGLKVEITHCGTMRRKYRVCNVTRRAASTQTFPLQLESGQTIECSVARYFQEKHSKT
LQFPFLPCLQVGQEQKHTYLPIEVCNIVQGQRCIKKLTDSQTSTMIKATARSAPDREKEI
AQLVRKAQFNNDPYVKEFGIQVIDEMTEVRGRVLPPPKIQYGG-----------------
-DVSSTP----------NQGVWDMRGKQFHSGISIDVWAIACFAHQR-------------
-MCSDQHLRTFIKSLQRISEDAGMPIRGTPVFCKYAQGSEHVEPLFRHLCDEFRALQLIV
VILPGKTPVYAEVKRVGDTLLGIATQCVQVKNVVKTSPQTLSNLCLKINVKLGGVNNILV
PSLRPKVFNDPVIFFGADVTHPPAGDTRKPSIAAVVGSMDAHPSRYSATVRVQQHRE---
------------------------EIIRDLAIMVRDLMVEFYKATH-YKPVRVIMYRDGV
SEGQFQQ-VLSTELRAIREACTMLEVGYQPGITFIVVQKRHHTRLFCRNHEDRSGKSGNI
PAGTTVDIGICHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNNFMADELQVLTYQLCHTY
VRCTRSVSIPAPAYYAHLVAFRARYHLVDKDHDSGEGSLQSGHTQHDQDAQLQAMSKAVV
VHENTVRNMYFA
>Hs-eIF2C2
VF--DGRKNLYTAMPLPIGRDKVELMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQH
FKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQ
ALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFG
FHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQ--QKPLTDSQRVKFT
KEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLV
LRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEI
SKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGR----------------
NKAIATP----------VQGVWDMRNKQFHTGIEIKVWAIACFAPQR-------------
-QCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVV
VILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILL
PQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQ---
------------------------KIIQDLAAMVRELLIQFYKSTR-FKPTRIIFYRDGV
SEGQFQQ-VLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNI
PAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTY
VRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSN---GRDHQALAKAVQ
VHQDTLRTMYFA