--------------------------------------------------------------------------------
Domain name : PF01544.10_CorA
Domain size : 407
Domain gathering score : -61.3000
Domain gathering score(TMSP) : 28.57
Domain gathering score(non-TMSP) : -80.17
Domain architecture : TM/SP [341 407], non-TM/SP [1 340]
Total query sequences in database : 2717
--------------------------------------------------------------------------------
A1VBK5 A1VBK5_DESVV Mg2+ transporter protein, CorA family protein [Desulfovibrio vulgaris DP4]
CorA            CorA-like Mg2+ transporter protein       20.4    3.4e-07   1
CorA              1/1      54   343 ..     1   407 []    20.4  3.4e-07
CorA: domain 1 of 1, from 54 to 343: score 20.4, E = 3.4e-07
                   *->gnvvsWidldapgneevlevDKstimkRvkkiaeglkardL.riedp
                      g v++ +d+d  ++ +++              ++gl+++ L+ ++ +
      A1VBK5    54    GIVWYDMDIDMDDDPTPA------------LTGLGLPPHILeSCLAT 88   

                   visyprsilgkvedyedylfvrekaivhsffyvqdeeEtNlnlehikaiI
                     ++  + ++          v +++ v       ++ +   + +++  + 
      A1VBK5    89 RRFPETEAFA--------GGVLLHMPV------RQQWNA-PRATYLTLLM 123  

                   tanevlTlDssrereipffdelrkRlpvgneqragQaSkkgqndgdllek
                    a  v+ l   ++ ++p+  +  +Rl  g++++ g               
      A1VBK5   124 LAGKVVSL---HRAPLPVTVKTAQRLTMGDAPHLG--------------- 155  

                   gplpfefraLEaale.sycsfLekieaeLekledpiLdeltskfhd.vDr
                    +  +++ +LEa++e+++ +f+e++++ +e+l +  Lde  +  + +vD 
      A1VBK5   156 LARDLFLYLLEAVIEtNIQNFVEARSH-IEELSR-TLDETPD--AVgVDD 201  

                   IstenLerirelkrrlvtLrrriqplrdvlerLlrddeDlaelYLTrKla
                           i+ +kr + +L+    +   +l++L+  +             
      A1VBK5   202 --------ILPFKRNVARLTVQHEEQFYCLTALQGIFA------------ 231  

                   qasssasdsveinsyltsptigakisrskssstrsatssstdeddveEve
                                                            +  +++   
      A1VBK5   232 -----------------------------------------GGAPNAQRD 240  

                   mlLedyydhidsllnkietlreyidslediINIyLsnvrnklneimklLT
                     L+d +d +  l   +++++  ++++++ +      ++ +  +  ++LT
      A1VBK5   241 PRLRDMLDTQAHLARSADRMEYRLRDMQQHCHY---VMQERTEQRLRILT 287  

                   vgttifapltlIAGiyGMNFkiglfmpelewkygYplvlglmailaivlf
                   + + i +pltlIAGiyGMNFk    mpel+w ygY++vlglma+ a++l+
      A1VBK5   288 ILSSIYMPLTLIAGIYGMNFK---AMPELDWEYGYFAVLGLMAATAAGLL 334  

                   liilsyfrrKgwl<-*
                        +frr+gwl   
      A1VBK5   335 W----FFRRRGWL    343  

TMSP/non-TMSP/fixed score (recomputed/original total): 114.649/-85.916/-9.519 (19.214/20.4)


A9UZ98 A9UZ98_MONBE Predicted protein [Monosiga brevicollis]
CorA            CorA-like Mg2+ transporter protein      -20.7    3.6e-05   1
CorA              1/1     342   635 ..     1   407 []   -20.7  3.6e-05
CorA: domain 1 of 1, from 342 to 635: score -20.7, E = 3.6e-05
                   *->gnvvsWidldapgneevlevDKstimkRvkkiaeglkardLriedpv
                      +  +sW+ +++ + + +        m +v     +l ++   ++d+v
      A9UZ98   342    RPIRSWVTVKGYDPNVAD-------MLSV-----ALDIHEEILQDVV 376  

                   isyprsilgkvedye......dylfvrekaivhsffyvqdeeEtN.....
                      +r    k+e++ +++++  ++++  +a +            N++   
      A9UZ98   377 -TIQR---DKIEIVGppekpfAHILASVYAMN------------Nspiyv 410  

                   ..lnlehikaiItanevlTlDssrereipffdelrkRlpvgneqragQaS
                   ++  l +++  ++ n             +++ ++r+R            +
      A9UZ98   411 psYGLANVYVKLGPNV------------KVVTIVRSRW----------FD 438  

                   .k.k.g.qndgdllekgplpfefraLEaalesycsfLekieaeLekledp
                       +++  d+d+l+   + +  ++ +++++++ +++   ++ L  l  +
      A9UZ98   439 vFlLgSgVWDPDVLDSPVYNVVRELEDQIIRRFPDVILGNVKYLAYLFLE 488  

                   iLdeltskfhdvDrIstenLerirelkrrlvtLrrriqplrdvlerLlrd
                   + +el                                 ++rdvl++ l+ 
      A9UZ98   489 AVSELNY-------------------------------DMRDVLKQWLEM 507  

                   deDlaelYLTrKlaqasssasdsv.einsyltsptigakisrskssstrs
                    +D                  +s+++                        
      A9UZ98   508 IDDG-----------------ISQtP------------------------ 516  

                   atssstdeddveEvemlLedyydhidsllnkietlreyidslediINIyL
                             +e+   l+e  y ++ sl  + +++  ++++l+ +     
      A9UZ98   517 ---------RPEHRAHLFE--YAKVSSL--YMREMSALANRLHTL---RW 550  

                   s.............nvrnkl.neimklLTvgttifapltlIAGiyGMNFk
                   + + ++ +   ++++v+ +++n   +lLT +ttif+p+ +++G++GMNF+
      A9UZ98   551 DakvepfsfffqneSVQDEQtNNVLLLLTLVTTIFIPAQFLTGLWGMNFE 600  

                   iglfmpelewkygYplvlglmailaivlfliilsyfrrKgwl<-*
                      +mpel+w+ygY + ++l+a ++i+  l    +fr  g     
      A9UZ98   601 ---EMPELHWRYGYVMFWSLVAGFTIITIL----WFRLSGYW    635  

TMSP/non-TMSP/fixed score (recomputed/original total): 86.863/-99.269/-9.519 (-21.925/-20.7)


B2AR81 B2AR81_PODAN Predicted CDS Pa_4_8350 [Podospora anserina]
CorA           CorA-like Mg2+ transporter protein       -51.1     0.0011   1
CorA             1/1     866  1192 ..     1   407 []   -51.1   0.0011
CorA: domain 1 of 1, from 866 to 1192: score -51.1, E = 0.0011
                   *->gnvvsWidldapgneevlevDKstimkRvkkiaeglkardLriedpv
                      ++ ++W  +d+++ ++ +                  + r     ++ 
      B2AR81   866    DQLWLW-SIDKTTLTTFF------------------PRRYSTPTEGT 893  

                   isyprsilgkvedyedylfvrekaivhsffyvqdeeEtN.......lnle
                   ++++                 ++  v        ++E N++ ++++ n  
      B2AR81   894 LFHQA---------------DLRNSV--------YNELNgdltgrtENAL 920  

                   hikaiItanevlTlDssrereipffdelrkRlpvgneqragQaSkkgqnd
                    + a+I  + v  +             l +                    
      B2AR81   921 DLAALIVYHAVIVF-------------LDRST------------------ 939  

                   gdllekgplpfefraLEaalesycsfLekieaeLekledpiLdeltskfh
                          p+   fr++++a+   ++++    ++ +    ++ d+++++  
      B2AR81   940 ------HPDLEIFRLFDEAIGMLAERMTLNMKQFRLQSLSMDDDEDDE-- 981  

                   dvDr.............................IstenLerirelkrrlv
                     D + ++ +++++ + +++++++ ++++++++ +t+ L +++ lk++l+
      B2AR81   982 --DTdysdwegespasikkrhrkelerserenrENTSALLELADLKDELT 1029 

                   tLrrriqplrdvlerLlrddeDlaelYLTrKlaqasssasdsveinsylt
                    L  ++       +++++ +e +                           
      B2AR81  1030 VLQTLFKNQESTVKQMKDFYE-I--------------------------- 1051 

                   sptigakisrskssstrsatssstdeddveEvemlLedyydhidsllnki
                                              + +E++++ +   + +d+ l+++
      B2AR81  1052 ---------------------------HCKETRKNWQ---EPLDDALEYL 1071 

                   etlreyidslediINI.........................yLsnvrnkl
                   + +++ ++++ + +N ++++ ++  +  +++ + ++ + ++  +     +
      B2AR81  1072 DDFKGTVNEMIERVNTtrndyekmlemvqrqaqvdevrwsrLQAELASSQ 1121 

                   neimklLTvgttifapltlIAGiyGMNFk..iglfmpelewkygYplvlg
                   n  ++++T++t+if+plt+ +G++GMN  +  + +mp le+  + + +l 
      B2AR81  1122 NLSVMIFTTFTVIFLPLTFFTGLFGMNVTnwQEEHMPDLEQ--VGWISLP 1169 

                   lmailaivlfliilsyfrrKgwl<-*
                     ++l i+ ++++ s+   +g     
      B2AR81  1170 TSILLIIFSLVAAFSWRVQRGFK    1192 

TMSP/non-TMSP/fixed score (recomputed/original total): 44.379/-87.219/-9.519 (-52.359/-51.1)


B6HAK5 B6HAK5_PENCW Pc16g13140 protein [Penicillium chrysogenum Wisconsin 54-1255]
CorA           CorA-like Mg2+ transporter protein       -59.8      0.003   1
CorA             1/1     698  1041 ..     1   407 []   -59.8    0.003
CorA: domain 1 of 1, from 698 to 1041: score -59.8, E = 0.003
                   *->gnvvsWi...dldapgneevlevDKstimkRvkkiaeglkardLrie
                      ++ + W+ +++l+ +   +++                     d  ++
      B6HAK5   698    DQLWMWVlgtNLIVTAFPQRW---------------------DQPKN 723  

                   dpvisyprsilgkvedyedylfvrekaivhsffyvqdeeEtN......ln
                   dp+++      g           +   i+             +++++   
      B6HAK5   724 DPLNVLD----G-----------VIEVIN------------SktrdpvKS 746  

                   lehikaiItanevlTlD..ssrereipffdelrkRl..............
                      +  iIt+     +D++++  +e++f+d +++ ++  +++++   ++ 
      B6HAK5   747 VYDLAMIITNRCSGVFDrhRLGDEEYQFLDMFESSIgiatdketvlfnqf 796  

                   .............................pvgneqragQaSkkgqndgdl
                   ++ +++ ++  +++++ +++ ++++++ ++  ++ +++          ++
      B6HAK5   797 nhasgqasdwlkshrklngsfssppkscnGTDDKDESS----------NY 836  

                   lekgplpfef.raLEaalesycsfLekieaeLekledpiLdeltskfhdv
                   +++++ p++ +r+L++           +e+ L ++ + i del +     
      B6HAK5   837 CDEDGQPLFVdRLLDI----------GQETNLLAETKDIRDELNM----- 871  

                   DrIstenLerirelkrrl...................vtLrrriqplrdv
                          +++++e +  +  + ++   ++ +++++++ ++++r+ + +++
      B6HAK5   872 -------IRTVLEHQNNVlldfqevicetyqgqhrsqFEVKKRFKDQQRM 914  

                   l.erLlrddeDlaelYLTrKlaqasssasdsveinsyltsptigakisrs
                   ++++L++ d+                                        
      B6HAK5   915 IdMHLKDIDR---------------------------------------- 924  

                   kssstrsatssstdeddveEvemlLedyydhidslln..kietlreyids
                                       + ++ e++y  i++ll+ ++  ++   +++
      B6HAK5   925 --------------------MDKQAERIYHSITDLLDlkQKHANAFEARF 954  

                   lediINIyLsnvrnklneimklLTvgttifapltlIAGiyGMNFkiglfm
                    +d      ++   ++ + ++++T++t +f+pl++IA+i+  N+k   + 
      B6HAK5   955 ARDQ-----AAGTTRQSKTIMVFTIVTIVFLPLSFIASIFTINLK---EF 996  

                   pelewkygYplvlglmailaivlfliil......syfrr..Kgwl<-*
                    +l+  y+ +++ g++++++i l+ ++l+ ++ +++fr ++++wl   
      B6HAK5   997 EHLNLGYVAKYTFGIGFAISIPLVWVALtvddigGFFRVgsRRWL    1041 

TMSP/non-TMSP/fixed score (recomputed/original total): 34.775/-86.419/-9.519 (-61.163/-59.8)


C1MQH9 C1MQH9_9CHLO CorA metal ion transporter family [Micromonas pusilla CCMP1545]
CorA         CorA-like Mg2+ transporter protein         -47.5    0.00074   1
CorA           1/1     146   422 ..     1   407 []   -47.5  0.00074
CorA: domain 1 of 1, from 146 to 422: score -47.5, E = 0.00074
                   *->gnvvsWidldapgneevlevDKstimkRvkkiaeglkardLriedpv
                      +  ++++  ++  + + +                        +  ++
      C1MQH9   146    TTQRLVMMRHRDPALRFF---------------------GTHAFLTM 171  

                   isyprsilgkvedyedylfvrek.aivhsffyvqdeeEtNlnlehikaiI
                   +   r   +          ++e++  +             +   ++++i 
      C1MQH9   172 QLLDR---E----------DCEGdIPL-------------VTDDQVSFIY 195  

                   tanevlTlDssrereipf.fdelrkRlpvgneqragQaSkkgqndgdlle
                     +  l++   + r+i+ +f +l++ l       +g          ++++
      C1MQH9   196 VPEMRLIVSVTEDRDIESdFTNLQSLL------VNG---------SSVCN 230  

                   kgplp...fefraLEaalesycsfLekieaeLekledpiLdeltskfhdv
                   k++ ++  ++  + +  ++  ++  e+ ++ Le l + + + +   ++  
      C1MQH9   231 KNGAHpamLLALLADKFVDDAFPLAEELGDFLEVLSHAMVSREGI-AYN- 278  

                   DrIstenLerirelkrrlvtLrrriqplrdvlerLlrddeDlaelYLTrK
                           + + + +  l+++rr  + +++    L + +e          
      C1MQH9   279 --------QPVDKTRMQLWRMRRFSIRVKR----LCETYE---------- 306  

                   laqasssasdsveinsyltsptigakisrskssstrsatssstdeddveE
                                                                   e+
      C1MQH9   307 ------------------------------------------------ED 308  

                   vemlLedyydhidsllnkietlreyidslediINIyLs...........n
                     +l+ d     d    +ie+ +    +le+ +  y ++     ++ + +
      C1MQH9   309 ALNLFGD-----DAFQTYIEAVEKQSENLEHVCDMYITrclailervevY 353  

                   vrnklneimklLTvgttifapltlIAGiyGMNFkiglfmpelewkygYpl
                   ++ k n    +LT++t++++p  +++G +GMNF    +mpel   +gY+l
      C1MQH9   354 QNQKTNDTLFILTIITVMMVPSQFLTGMWGMNFV---NMPELGLSWGYWL 400  

                   vlglmailaivlfliilsyfrrKgwl<-*
                    l l+ ++ i++f+     ++  g l   
      C1MQH9   401 FLALIPTFMIGIFV----LLKMGGYL    422  

TMSP/non-TMSP/fixed score (recomputed/original total): 55.558/-94.616/-9.519 (-48.577/-47.5)


C1N623 C1N623_9CHLO CorA metal ion transporter family [Micromonas pusilla CCMP1545]
CorA          CorA-like Mg2+ transporter protein        -40.8    0.00035   1
CorA            1/1     180   447 ..     1   407 []   -40.8  0.00035
CorA: domain 1 of 1, from 180 to 447: score -40.8, E = 0.00035
                   *->gnvvsWidldapgneevlevDKstimkRvkkiaeglkardLriedpv
                       +++ +  +d +  ++++ +D+ + +             +L + + v
      C1N623   180    HKDAAVRHFDSHVYVSMQLIDREECDGDI----------PLVSDEQV 216  

                   isyprsilgkvedyedylfvrekaivhsffyvqdeeEtNlnlehikaiIt
                   ++  +   +            ekaiv   + ++d++E+  + + +  ++ 
      C1N623   217 SFIYH---P------------EKAIV--ISVCEDVDEE-SDFTALTRLLV 248  

                   anevlTlDssrereipffdelrkRlpvgneqragQaSkkgqndgdllekg
                   + e                   +R                    ++ +  
      C1N623   249 EGE-------------------SRC-------------------NVDGAH 260  

                   plpfefraLEaalesycsfLekieaeLekledpiLdeltskfhd.vDrIs
                   p+ ++ +  +  ++   ++ e+ ++ Le l + + + ++  f  +vD+  
      C1N623   261 PGILLAMMADKFVDDAYPVAEELGDYLEVLSQAMVARESISFSQpVDK-- 308  

                   tenLerirelkrrlvtLrrriqplrdvlerLlrddeDlaelYLTrKlaqa
                             +  l+++rr ++ +r+  e+  +d +              
      C1N623   309 ---------VRMQLWRMRRFAIRVRRLCEAYEEDAL-------------- 335  

                   sssasdsveinsyltsptigakisrskssstrsatssstdeddveEveml
                                                          +  d+e  +++
      C1N623   336 ---------------------------------------GVFDDESFKEY 346  

                   LedyydhidsllnkietlreyidslediINIyLsnvrnklneimklLTvg
                      + +++d+l  + e + +   s+ +       ++  + ne   lLT++
      C1N623   347 VGKVSKQADGLESVCEMYIGRCLSILQR---VEVYQEQRTNETLFLLTIV 393  

                   ttifapltlIAGiyGMNFkiglfmpelewkygYplvlglmailaivlfli
                   tt ++p  +++G +GMNF    +mp le  +gY++ l l+ +l +  ++ 
      C1N623   394 TTLMVPVEFLTGMWGMNFV---NMPDLETSWGYFMFLALIPFLMGTSYI- 439  

                   ilsyfrrKgwl<-*
                       ++  g l   
      C1N623   440 ---LLKVNGYL    447  

TMSP/non-TMSP/fixed score (recomputed/original total): 48.613/-80.945/-9.519 (-41.851/-40.8)


C2EA24 C2EA24_9LACO Putative uncharacterized protein [Lactobacillus ruminis ATCC 25644]
CorA           CorA-like Mg2+ transporter protein       -11.8    1.3e-05   1
CorA             1/1     196   451 .]     1   407 []   -11.8  1.3e-05
CorA: domain 1 of 1, from 196 to 451: score -11.8, E = 1.3e-05
                   *->gnvvsWidldapgneevlevDKstimkRvkkiaeglkardLriedpv
                      g+++  +d+++ +   ++                       ++++ +
      C2EA24   196    GEKYTTVDIIGDEIFGTM-----------------------ALLNRN 219  

                   isyprsilgkvedyedylfvrekaivhsffyvqdeeEtNlnlehikaiIt
                   +   +   g        +fvr+++                  e + +i +
      C2EA24   220 NLLGK---G--------IFVRYHLSE----------------ERLIFIDK 242  

                   anevlTlDssrereipffdelrkRlpvgneqragQaSkkgqndgdllekg
                         +        +++++   +       ++            ++   
      C2EA24   243 SGI---M---ASCLADCVESQNVKS------HNL---------AQVFLNC 271  

                   plpfefraLEaalesycsf.LekieaeLekledpiLdeltskfhdvDrIs
                    +++ +r  +  + + c+++L+  e+   + + +i ++ +          
      C2EA24   272 IYHLTYR--DDFFFNDCERkLDLLEDNMVDNVLEIPHDFE---------- 309  

                   tenLerirelkrrlvtLrrriqplrdvlerLlrddeDlaelYLTrKlaqa
                    e + +i + +r l+++ + + +l + + +   d++D +           
      C2EA24   310 -EYIFKIKKEQRHLMRFYKQLTELVTNIAESGVDYLDEI----------- 347  

                   sssasdsveinsyltsptigakisrskssstrsatssstdeddveEveml
                                                             +  ++ m 
      C2EA24   348 ------------------------------------------NLTDMQMV 355  

                   LedyydhidsllnkietlreyidslediINIyLsnvrnklneimklLTvg
                    +    ++ +l  ++ ++ ey+  + d    y + +++++n+ m +LT++
      C2EA24   356 AN----RLSRLNLEAQSMSEYATQIIDT---YQAKINVRQNKVMQILTIV 398  

                   ttifapltlIAGiyGMNFkiglfmpelewkygYplvlglmailaivlfli
                   ttif+pltlI+G yGMNF      pe+ wkygY+ +++  +i+ ++  + 
      C2EA24   399 TTIFMPLTLITGWYGMNFN----IPETTWKYGYLIAIISSIIIIAIEII- 443  

                   ilsyfrrKgwl<-*
                       f++ +w+   
      C2EA24   444 ---LFKKEKWM    451  

TMSP/non-TMSP/fixed score (recomputed/original total): 79.508/-82.763/-9.519 (-12.774/-11.8)


C2EUV4 C2EUV4_9LACO MIT family metal ion transporter CorA [Lactobacillus vaginalis ATCC 49540]
CorA         CorA-like Mg2+ transporter protein         -56.7     0.0021   1
CorA           1/1       8   304 ..     1   407 []   -56.7   0.0021
CorA: domain 1 of 1, from 8 to 304: score -56.7, E = 0.0021
                   *->gnvvsWidldapgneevle.vDKstimkRvkkiaeglkardLriedp
                          +Wi +++p  +e+++ + K++  k++              +d+
      C2EUV4     8    NAHSWWISVFEPLPHERQDlIQKYEVTKEL--------------LDY 40   

                   visyprsilgkvedyedylfvrekaivhsffyvqdeeEtNlnlehikaiI
                   +i + ++    v+ ++   ++++   v     +  e      +  i + +
      C2EUV4    41 AIDPYEKARVEVDPDAGVTLLIFDVYV-----PTHEVTA-PQTAPIGIML 84   

                   tanevlTlDssrereipffd.elrkRlpvgneqragQaSkkgqndgdlle
                   t+n + T+    + +  f+++ + ++l      +          ++d ++
      C2EUV4    85 TNNNLITF---TNAKTNFVNgTIANQL------KRL-------QNRDTVV 118  

                   kgplpfefraLEaalesycsfLekieaeLekledpiLdeltskfhdvDrI
                   +    ++  +    ++++ +    ++++ ++  +  L ++t++       
      C2EUV4   119 EKLNLVLAVLYRLSTDYFGPL--RRVDQKRQQIQRSLQGRTGR------- 159  

                   stenLerirelkrrlvtLrrriqplrdvlerLlrddeDlaelYLTrKlaq
                       + +  e+++ lv+++ ++      le++ r+  ++           
      C2EUV4   160 --KAITEFMEIETGLVYMLTSLKGNVSLLEEFERRMNPI----------- 196  

                   asssasdsveinsyltsptigakisrskssstrsatssstdeddveEvem
                                                               +  +++
      C2EUV4   197 -------------------------------------------MSTRQRN 203  

                   lLedyydhidsllnkietlreyidslediINIyLsnvrnklneimklLTv
                   +L d+ + + + l+++    +   +  ++   y       ln+ mk+LT+
      C2EUV4   204 DLDDVIVEAQQGLEMAQMTSDVSARVSNA---YSKVLDSDLNQTMKFLTI 250  

                   gttifapltlIAGiyGMNFkiglfmpelewkygYplvlglmailaivlfl
                    +  ++++t +AG yG N       p+ +      +++++++++ai+l +
      C2EUV4   251 YSILLSIPTIVAGFYGENVA----LPLANK----SYSWIITIVIAILLMI 292  

                   iilsyfrrKgwl<-*
                   +   ++ rK w    
      C2EUV4   293 LCAVFLIRKDWW    304  

TMSP/non-TMSP/fixed score (recomputed/original total): 35.071/-83.446/-9.519 (-57.894/-56.7)


C2YTJ4 C2YTJ4_BACCE Magnesium and cobalt transport protein [Bacillus cereus AH1271]
CorA     CorA-like Mg2+ transporter protein             -36.6    0.00022   1
CorA       1/1       1   174 [.     1   407 []   -36.6  0.00022
CorA: domain 1 of 1, from 1 to 174: score -36.6, E = 0.00022
                   *->gnvvsWidldapgneevlevDKstimkRvkkiaeglkardLriedpv
                                      ++                   ++ Lr  d++
      C2YTJ4     1    ----------------MF------------------ISHYLREVDYF 13   

                   isyprsilgkvedyedylfvrekaivhsffyvqdeeEtNlnlehikaiIt
                    ++ r++l             ++ ++          ++   le+i+ i  
      C2YTJ4    14 ENHFRNVLW-----------DFYHHN----------NI-AVLEKIYHI-- 39   

                   anevlTlDssrereipffdelrkRlpvgneqragQaSkkgqndgdllekg
                   ++e++           +f+ +++ l                         
      C2YTJ4    40 RHELFMN-------THVFRLIQEVL------------------------- 57   

                   plpfefraLEaalesycsfLekieaeLekledpiLdeltskfhdvDrIst
                                              + le+  L++ t+          
      C2YTJ4    58 ---------------------------QGLEEAWLENITN---------- 70   

                   enLerirelkrrlvtLrrriqplrdvlerLlrddeDlaelYLTrKlaqas
                                                    ++               
      C2YTJ4    71 ---------------------------------TL--------------- 72   

                   ssasdsveinsyltsptigakisrskssstrsatssstdeddveEvemlL
                                                              + + + L
      C2YTJ4    73 -----------------------------------------CYKQTHLKL 81   

                   edyydhidsllnkietlreyidslediINIyLsnvrnklneimklLTvgt
                   e       + l+   ++ e +d + ++   +    +++ neimk LTv t
      C2YTJ4    82 E-------RGLQLVKEYQEELDTMIHL---QEVVSSHRGNEIMKALTVLT 121  

                   tifapltlIAGiyGMNFkiglfmpelewkygYplvlglmailaivlflii
                    + +plt++++++GMNFk   +mpelewky Y+ +l+ +++ +++++l  
      C2YTJ4   122 AVSTPLTALGALWGMNFK---YMPELEWKYSYLIALLFIIFTTGGMYL-- 166  

                   lsyfrrKgwl<-*
                     y r Kgw    
      C2YTJ4   167 --YMRFKGWT    174  

TMSP/non-TMSP/fixed score (recomputed/original total): 94.025/-117.322/-13.979 (-37.276/-36.6)


C3MUS4 C3MUS4_SULIM Putative uncharacterized protein [Sulfolobus islandicus M.14.25]
CorA            CorA-like Mg2+ transporter protein      -47.9    0.00078   1
CorA              1/1      16   245 .]     1   407 []   -47.9  0.00078
CorA: domain 1 of 1, from 16 to 245: score -47.9, E = 0.00078
                   *->gnvvsWidldapgneevlevDKstimkRvkkiaeglkardLriedpv
                       ++v ++++ +++ +  +                      L  +d+ 
      C3MUS4    16    KSDVDVYRVLEEDGKYYI---------------------RLE-LDGK 40   

                   isyprsilgkvedyedylfvrekaivhsffyvqdeeEtNlnlehikaiIt
                    +y                +  + iv             l++ +++  + 
      C3MUS4    41 PMYLT--------------FSANEIV-------------LHSKELYEMVS 63   

                   anevlTlDssrereipffdelrkRlpvgneqragQaSkkgqndgdllekg
                   ++e   +   + +++ ++de+   +        +            l+  
      C3MUS4    64 REE---I--DDCSPLGILDEIFYII------LYQ------------LGTK 90   

                   plpfefraLEaalesycsfLekieaeLekledpiLdeltskfhdvDrIst
                      ++++ ++ +++ + s   k ++++  l++ iL ++++          
      C3MUS4    91 RTQLFLE-FDNLFDLITSGKIKDSKRIILLRKRILTNYSDS--------- 130  

                   enLerirelkrrlvtLrrriqplrdvlerLlrddeDlaelYLTrKlaqas
                        i+   rrl++++               + e               
      C3MUS4   131 ---TVIYYVSRRLSKFL---------------SAE--------------- 147  

                   ssasdsveinsyltsptigakisrskssstrsatssstdeddveEvemlL
                                                             +e+v+ ++
      C3MUS4   148 -----------------------------------------SIEDVKFNY 156  

                   edyydhidsllnkietlreyidslediINIyLsnvrnklneimklLTvgt
                   e              + + ++ ++ d+ NIyL+ v+n lnei+k+LT ++
      C3MUS4   157 E--------------RAELLVTRSGDLYNIYLTEVQNDLNEIIKKLTSIS 192  

                   tifapltlIAGiyGMNFk.iglfmpelewkygYplvlglmailaivlfli
                   +if+p+t+IA+iy    +   +++ +++w++  +l+  l+ +  ++l++ 
      C3MUS4   193 FIFMPITAIASIYA--VDyTNVYNTLINWQSLIFLSPVLILT--VLLVI- 237  

                   ilsyfrrKgwl<-*
                      y+rr +wl   
      C3MUS4   238 ---YLRRIKWL    245  

TMSP/non-TMSP/fixed score (recomputed/original total): 41.799/-81.074/-9.519 (-48.794/-47.9)


C3MX52 C3MX52_SULIM Putative uncharacterized protein [Sulfolobus islandicus M.14.25]
CorA            CorA-like Mg2+ transporter protein      -47.9    0.00078   1
CorA              1/1      16   245 .]     1   407 []   -47.9  0.00078
CorA: domain 1 of 1, from 16 to 245: score -47.9, E = 0.00078
                   *->gnvvsWidldapgneevlevDKstimkRvkkiaeglkardLriedpv
                       ++v ++++ +++ +  +                      L  +d+ 
      C3MX52    16    KSDVDVYRVLEEDGKYYI---------------------RLE-LDGK 40   

                   isyprsilgkvedyedylfvrekaivhsffyvqdeeEtNlnlehikaiIt
                    +y                +  + iv             l++ +++  + 
      C3MX52    41 PMYLT--------------FSANEIV-------------LHSKELYEMVS 63   

                   anevlTlDssrereipffdelrkRlpvgneqragQaSkkgqndgdllekg
                   ++e   +   + +++ ++de+   +        +            l+  
      C3MX52    64 REE---I--DDCSPLGILDEIFYII------LYQ------------LGTK 90   

                   plpfefraLEaalesycsfLekieaeLekledpiLdeltskfhdvDrIst
                      ++++ ++ +++ + s   k ++++  l++ iL ++++          
      C3MX52    91 RTQLFLE-FDNLFDLITSGKIKDSKRIILLRKRILTNYSDS--------- 130  

                   enLerirelkrrlvtLrrriqplrdvlerLlrddeDlaelYLTrKlaqas
                        i+   rrl++++               + e               
      C3MX52   131 ---TVIYYVSRRLSKFL---------------SAE--------------- 147  

                   ssasdsveinsyltsptigakisrskssstrsatssstdeddveEvemlL
                                                             +e+v+ ++
      C3MX52   148 -----------------------------------------SIEDVKFNY 156  

                   edyydhidsllnkietlreyidslediINIyLsnvrnklneimklLTvgt
                   e              + + ++ ++ d+ NIyL+ v+n lnei+k+LT ++
      C3MX52   157 E--------------RAELLVTRSGDLYNIYLTEVQNDLNEIIKKLTSIS 192  

                   tifapltlIAGiyGMNFk.iglfmpelewkygYplvlglmailaivlfli
                   +if+p+t+IA+iy    +   +++ +++w++  +l+  l+ +  ++l++ 
      C3MX52   193 FIFMPITAIASIYA--VDyTNVYNTLINWQSLIFLSPVLILT--VLLVI- 237  

                   ilsyfrrKgwl<-*
                      y+rr +wl   
      C3MX52   238 ---YLRRIKWL    245  

TMSP/non-TMSP/fixed score (recomputed/original total): 41.799/-81.074/-9.519 (-48.794/-47.9)


C3N2H7 C3N2H7_SULIA Putative uncharacterized protein [Sulfolobus islandicus M.16.27]
CorA            CorA-like Mg2+ transporter protein      -47.9    0.00078   1
CorA              1/1      16   245 .]     1   407 []   -47.9  0.00078
CorA: domain 1 of 1, from 16 to 245: score -47.9, E = 0.00078
                   *->gnvvsWidldapgneevlevDKstimkRvkkiaeglkardLriedpv
                       ++v ++++ +++ +  +                      L  +d+ 
      C3N2H7    16    KSDVDVYRVLEEDGKYYI---------------------RLE-LDGK 40   

                   isyprsilgkvedyedylfvrekaivhsffyvqdeeEtNlnlehikaiIt
                    +y                +  + iv             l++ +++  + 
      C3N2H7    41 PMYLT--------------FSANEIV-------------LHSKELYEMVS 63   

                   anevlTlDssrereipffdelrkRlpvgneqragQaSkkgqndgdllekg
                   ++e   +   + +++ ++de+   +        +            l+  
      C3N2H7    64 REE---I--DDCSPLGILDEIFYII------LYQ------------LGTK 90   

                   plpfefraLEaalesycsfLekieaeLekledpiLdeltskfhdvDrIst
                      ++++ ++ +++ + s   k ++++  l++ iL ++++          
      C3N2H7    91 RTQLFLE-FDNLFDLITSGKIKDSKRIILLRKRILTNYSDS--------- 130  

                   enLerirelkrrlvtLrrriqplrdvlerLlrddeDlaelYLTrKlaqas
                        i+   rrl++++               + e               
      C3N2H7   131 ---TVIYYVSRRLSKFL---------------SAE--------------- 147  

                   ssasdsveinsyltsptigakisrskssstrsatssstdeddveEvemlL
                                                             +e+v+ ++
      C3N2H7   148 -----------------------------------------SIEDVKFNY 156  

                   edyydhidsllnkietlreyidslediINIyLsnvrnklneimklLTvgt
                   e              + + ++ ++ d+ NIyL+ v+n lnei+k+LT ++
      C3N2H7   157 E--------------RAELLVTRSGDLYNIYLTEVQNDLNEIIKKLTSIS 192  

                   tifapltlIAGiyGMNFk.iglfmpelewkygYplvlglmailaivlfli
                   +if+p+t+IA+iy    +   +++ +++w++  +l+  l+ +  ++l++ 
      C3N2H7   193 FIFMPITAIASIYA--VDyTNVYNTLINWQSLIFLSPVLILT--VLLVI- 237  

                   ilsyfrrKgwl<-*
                      y+rr +wl   
      C3N2H7   238 ---YLRRIKWL    245  

TMSP/non-TMSP/fixed score (recomputed/original total): 41.799/-81.074/-9.519 (-48.794/-47.9)


C4KDY6 C4KDY6_SULIK Putative uncharacterized protein [Sulfolobus islandicus M.16.4]
CorA            CorA-like Mg2+ transporter protein      -47.9    0.00078   1
CorA              1/1      16   245 .]     1   407 []   -47.9  0.00078
CorA: domain 1 of 1, from 16 to 245: score -47.9, E = 0.00078
                   *->gnvvsWidldapgneevlevDKstimkRvkkiaeglkardLriedpv
                       ++v ++++ +++ +  +                      L  +d+ 
      C4KDY6    16    KSDVDVYRVLEEDGKYYI---------------------RLE-LDGK 40   

                   isyprsilgkvedyedylfvrekaivhsffyvqdeeEtNlnlehikaiIt
                    +y                +  + iv             l++ +++  + 
      C4KDY6    41 PMYLT--------------FSANEIV-------------LHSKELYEMVS 63   

                   anevlTlDssrereipffdelrkRlpvgneqragQaSkkgqndgdllekg
                   ++e   +   + +++ ++de+   +        +            l+  
      C4KDY6    64 REE---I--DDCSPLGILDEIFYII------LYQ------------LGTK 90   

                   plpfefraLEaalesycsfLekieaeLekledpiLdeltskfhdvDrIst
                      ++++ ++ +++ + s   k ++++  l++ iL ++++          
      C4KDY6    91 RTQLFLE-FDNLFDLITSGKIKDSKRIILLRKRILTNYSDS--------- 130  

                   enLerirelkrrlvtLrrriqplrdvlerLlrddeDlaelYLTrKlaqas
                        i+   rrl++++               + e               
      C4KDY6   131 ---TVIYYVSRRLSKFL---------------SAE--------------- 147  

                   ssasdsveinsyltsptigakisrskssstrsatssstdeddveEvemlL
                                                             +e+v+ ++
      C4KDY6   148 -----------------------------------------SIEDVKFNY 156  

                   edyydhidsllnkietlreyidslediINIyLsnvrnklneimklLTvgt
                   e              + + ++ ++ d+ NIyL+ v+n lnei+k+LT ++
      C4KDY6   157 E--------------RAELLVTRSGDLYNIYLTEVQNDLNEIIKKLTSIS 192  

                   tifapltlIAGiyGMNFk.iglfmpelewkygYplvlglmailaivlfli
                   +if+p+t+IA+iy    +   +++ +++w++  +l+  l+ +  ++l++ 
      C4KDY6   193 FIFMPITAIASIYA--VDyTNVYNTLINWQSLIFLSPVLILT--VLLVI- 237  

                   ilsyfrrKgwl<-*
                      y+rr +wl   
      C4KDY6   238 ---YLRRIKWL    245  

TMSP/non-TMSP/fixed score (recomputed/original total): 41.799/-81.074/-9.519 (-48.794/-47.9)


Q729B6 Q729B6_DESVH Transporter, CorA family [Desulfovibrio vulgaris str. Hildenborough]
CorA            CorA-like Mg2+ transporter protein       20.4    3.4e-07   1
CorA              1/1      54   343 ..     1   407 []    20.4  3.4e-07
CorA: domain 1 of 1, from 54 to 343: score 20.4, E = 3.4e-07
                   *->gnvvsWidldapgneevlevDKstimkRvkkiaeglkardL.riedp
                      g v++ +d+d  ++ +++              ++gl+++ L+ ++ +
      Q729B6    54    GIVWYDMDIDMDDDPTPA------------LTGLGLPPHILeSCLAT 88   

                   visyprsilgkvedyedylfvrekaivhsffyvqdeeEtNlnlehikaiI
                     ++  + ++          v +++ v       ++ +   + +++  + 
      Q729B6    89 RRFPETEAFA--------GGVLLHMPV------RQQWNA-PRATYLTLLM 123  

                   tanevlTlDssrereipffdelrkRlpvgneqragQaSkkgqndgdllek
                    a  v+ l   ++ ++p+  +  +Rl  g++++ g               
      Q729B6   124 LAGKVVSL---HRAPLPVTVKTAQRLTMGDAPHLG--------------- 155  

                   gplpfefraLEaale.sycsfLekieaeLekledpiLdeltskfhd.vDr
                    +  +++ +LEa++e+++ +f+e++++ +e+l +  Lde  +  + +vD 
      Q729B6   156 LARDLFLYLLEAVIEtNIQNFVEARSH-IEELSR-TLDETPD--AVgVDD 201  

                   IstenLerirelkrrlvtLrrriqplrdvlerLlrddeDlaelYLTrKla
                           i+ +kr + +L+    +   +l++L+  +             
      Q729B6   202 --------ILPFKRNVARLTVQHEEQFYCLTALQGIFA------------ 231  

                   qasssasdsveinsyltsptigakisrskssstrsatssstdeddveEve
                                                            +  +++   
      Q729B6   232 -----------------------------------------GGAPNAQRD 240  

                   mlLedyydhidsllnkietlreyidslediINIyLsnvrnklneimklLT
                     L+d +d +  l   +++++  ++++++ +      ++ +  +  ++LT
      Q729B6   241 PRLRDMLDTQAHLARSADRMEYRLRDMQQHCHY---VMQERTEQRLRILT 287  

                   vgttifapltlIAGiyGMNFkiglfmpelewkygYplvlglmailaivlf
                   + + i +pltlIAGiyGMNFk    mpel+w ygY++vlglma+ a++l+
      Q729B6   288 ILSSIYMPLTLIAGIYGMNFK---AMPELDWEYGYFAVLGLMAATAAGLL 334  

                   liilsyfrrKgwl<-*
                        +frr+gwl   
      Q729B6   335 W----FFRRRGWL    343  

TMSP/non-TMSP/fixed score (recomputed/original total): 114.649/-85.916/-9.519 (19.214/20.4)


Q7U9V6 Q7U9V6_SYNPX Putative cation (Mg/Co) transporter, MIT family [Synechococcus sp. WH 8102]
CorA     CorA-like Mg2+ transporter protein             -50.0    0.00099   1
CorA       1/1       2   134 ..     1   407 []   -50.0  0.00099
CorA: domain 1 of 1, from 2 to 134: score -50.0, E = 0.00099
                   *->gnvvsWidldapgneevlevDKstimkRvkkiaeglkardLriedpv
                                      v+                     +Lr++ +v
      Q7U9V6     2    ----------------VW---------------------PLRSQLIV 11   

                   isyprsilgkvedyedylfvrekaivhsffyvqdeeEtNlnlehikaiIt
                   ++ +    g             k+++                        
      Q7U9V6    12 LVRQ----G-------------KRLL------------------------ 20   

                   anevlTlDssrereipffdelrkRlpvgneqragQaSkkgqndgdllekg
                             +++   +f+e+  ++                         
      Q7U9V6    21 ----------DREAVRGFREVSTHV------------------------- 35   

                   plpfefraLEaalesycsfLekieaeLekledpiLdeltskfhdvDrIst
                                                    +  e  +          
      Q7U9V6    36 --------------------------------DVVFETAE---------- 43   

                   enLerirelkrrlvtLrrriqplrdvlerLlrddeDlaelYLTrKlaqas
                                                                     
      Q7U9V6     - -------------------------------------------------- -    

                   ssasdsveinsyltsptigakisrskssstrsatssstdeddveEvemlL
                                                                     
      Q7U9V6     - -------------------------------------------------- -    

                   edyydhidsllnkietlreyidslediINIyLsnvrnklneimklLTvgt
                                   lr   d    +   y+++++n++n+ mk+LTv++
      Q7U9V6    44 ---------------VLRHQCDGVTAS---YMASISNRMNQVMKVLTVIS 75   

                   tifapltlIAGiyGMNFk...iglfmpelewkygYplvlglmailaivlf
                    if+plt+IAG+yGMNF+++ ++++mpelew+ygY l +  m+++++  +
      Q7U9V6    76 SIFVPLTFIAGVYGMNFDpevSPWNMPELEWPYGYVLCMVAMGLISLTQV 125  

                   liilsyfrrKgwl<-*
                   l    +frr+gw+   
      Q7U9V6   126 L----WFRRQGWF    134  

TMSP/non-TMSP/fixed score (recomputed/original total): 115.433/-151.975/-13.979 (-50.521/-50.0)


nonTMSP insignificant hits/no hmmpfamresult hits (total %) :15/71 (86 3.2%)
