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Domain name : PF01569.13_PAP2
Domain size : 177
Domain Description : PAP2 superfamily
Domain gathering score : 8.3000
Domain trusted cutoff : 8.4000
Domain architecture : non-TM/SP [1 199], TM [200 261]
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Example 1
gi|118103025|ref|XP_418136.2| PREDICTED: similar to Aoc2 protein [Gallus gallus] 1153 (length) 859 1000 .. (wrt seq) 1 177 [] (wrt HMM) 
No.of residues in non-TM/SP region : 143 [72%(over non-TM/SP length)]

Scores for sequence family classification:
Model        Description                                Score    E-value  N
--------     -----------                                -----    ------- ---
Cu_amine_oxid   Copper amine oxidase, enzyme domain     564.9   9.2e-167   1
Cu_amine_oxidN2 Copper amine oxidase, N2 domain          57.4    5.4e-14   1
PAP2            PAP2 superfamily                         54.1    5.3e-13   1
Cu_amine_oxidN3 Copper amine oxidase, N3 domain          52.9    1.3e-12   1
DUF1965         Domain of unknown function (DUF1965)     -8.7      0.051   1

Parsed for domains:
Model        Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------     ------- ----- -----    ----- -----      -----  -------
Cu_amine_oxid     1/1     301   714 ..     1   449 []   564.9 9.2e-167
Cu_amine_oxidN2   1/1      58   144 ..     1    91 []    57.4  5.4e-14
PAP2              1/1     859  1000 ..     1   177 []    54.1  5.3e-13
Cu_amine_oxidN3   1/1     161   258 ..     1   111 []    52.9  1.3e-12
DUF1965           1/1     226   290 ..     1    77 []    -8.7    0.051

Alignments of top-scoring domains:
Cu_amine_oxid: domain 1 of 1, from 301 to 714: score 564.9, E = 9.2e-167
                CS    S---EEEEE-TT-SSEEEETTTEEEETTEEEEEEEETTTEEEEEEEE
                   *->pdlkPLqitQPeGPsFrvtGgnlVeWanWsFhvGfdpReGlvIsdVr
                      p   PLq++ P+GP+++v++ n+V++++Ws  +G++p  G++++d+r
  gi|1181030   301    P--GPLQFE-PQGPRYSVRD-NRVTYQGWSIAFGMNPNTGPRLFDIR 343  

                CS EEETTEEEEEEEEEEEEEEEEEB-SSSTTTTTEEEEHHHHCTTTTTBB-S
                   fnDegtkRpVmYrgSlsEmvVPYGDpspawyrKnYfDsGEyGlGkmanpL
                   f++e    +++Y++Sl+E+ ++YG++ p+ + ++Y+D  ++G+G+ a +L
  gi|1181030   344 FRGE----RIIYELSLQEALALYGSNCPGGMSTRYLDG-SFGIGRFAYEL 388  

                CS TTTTSSTTSEEEEEE.EEESTTS-EEEEEEEEEEEEEEEEEEEEE EEST
                   spGcDCpgnatYlDaFhfadadGnPitipNAICvFEedaGlilwK.Hsdl
                   ++G+DCp+ atY+D  h+++++ +Pit  N +C+FE d++l+l+++ sd 
  gi|1181030   389 VRGVDCPYLATYVDR-HYLSESDVPITNQNSLCIFEHDTSLPLRRhFSDA 437  

                CS TCTT.ECEEEEEEEEEEEEEEEEETTEEEEEEEEEETTSEEEEEEEEEE-
                   rqnneginevrrsrkLVVrfisTVgNYDYifdWiFytdGaIeaevkATGI
                    +    +++++r+ +LV+r +sT+ NYDY++d+ Fy +Ga e++v+ATG+
  gi|1181030   438 HS---LYYGGLRKNTLVIRAVSTLINYDYVWDFMFYSNGAVEVRVHATGY 484  

                CS -EEEEESTTSTSTTHCCCTTTEEEEETTEEEEEEEEEEEEEEEETTTSSE
                   LnvkglkygnkDeigeeeeryGtlvsenvigpvHqHlfhfRlDldiDGlk
                   ++  +l ++        ++ yG+ v ++++g+ H H +h+++DldiDG  
  gi|1181030   485 ISSSFLHDQ--------GTNYGNKVGPHTLGTMHLHHIHYKVDLDIDGQL 526  

                CS EEEEEEEEEEEEEECCTTTSTTSEEEEEEEEEEEEEBBHHHHEETTSGGG
                   NsvvavdlKkvrvpmGapgnprgnalkalQlkrkllktEkdAafkldsat
                   Ns++  d+    ++m +p++p++ al+++ l r+ l++E +Aaf l+ ++
  gi|1181030   527 NSLESHDM--GYQTMRVPWSPEN-ALQQPYLRRERLERENEAAFPLNASL 573  

                CS TEEEEEEEEEEETTTS-CEEEEEEEEESBBSS-STTTSHHHHTHHHHHCG
                   pRtwlivNpnkkNrvGgnPvGYkLipgstatllldpdssparDWiYHRaa
                   pR +l ++ +k Nr+G + ++Y+ +  s++ + l+  s++++     +++
  gi|1181030   574 PR-YLSFTGPKPNRWG-HLRSYRVQVVSFPGEHLPTSSPMEK-----AIS 616  

                CS GGGSSEEEEE-TTT--STTTSS-TTTTSSSSS.SSSSHHHHHTT-CBSSS
                   FarnqLwVTpYkeeElyagGdYvnQsqgDgpWaPTdgLadwikrnrsIen
                   + r+ L+VT++keeE+ ++++Y   +q+D pW+PT+++ad+i+ +++I n
  gi|1181030   617 WGRYKLAVTRRKEEEPTSTSVY---NQND-PWTPTVTFADFIN-DETIAN 661  

                CS EEEEEEEEEEEEE--GGGGSSB.SEEEEEEEEEEEECSSSSSGTTTTCCS
                   tDiVvWhTfGftHvPraEDwPNTiMPvesvgFlLrPhNFFdenPsLdvpp
                   +D+V+W  +Gf+HvP+aED+PNT+++++ vgF+LrP+N Fde+PsL++p+
  gi|1181030   662 EDLVAWISVGFLHVPHAEDIPNTVTVGNGVGFFLRPYNYFDEDPSLYSPD 711  

                CS SEE   
                   sve<-*
                    ++   
  gi|1181030   712 GIY    714  

Cu_amine_oxidN2: domain 1 of 1, from 58 to 144: score 57.4, E = 5.4e-14
                CS    CTTSHHHHHHHHHHHHHHHHCT.TTTTTEEEEEEEEE--HHHHHHHH
                   *->HPLdpLtaeEinkvrtILkssallagkstrfhsveLlEPdKkaVlqw
                      ++L ++   +       L ++a +++++++++sv++++P+K++Vl++
  gi|1181030    58    EELAQVVQYLRGSLGVPLADAARAKPSDNCIASVDVQLPAKAEVLRF 104  

                CS HHSCSSSSSS-EEEEEEEEETTSSSEEEEEEETTTTEEEEEEEE   
                   lekggplvappRkArVvaldgaqtRshElvVDLttGkvvswril<-*
                   l+ gg    ppR+A +v+++gaq+   ++v++  +G+++ + ++   
  gi|1181030   105 LDAGGAR--PPREALAVLYFGAQA--EPNVTEYVVGPLPAPTYH    144  

PAP2: domain 1 of 1, from 859 to 1000: score 54.1, E = 5.3e-13
                CS    CCHHHHHHHHHHHHHHHHHHHHH CC-B--..HHHHHHHHHHHTT-G
                   *->aalalllalvaslllnglaylKl.lfgrpRApPhflavcqpdwgdst
                       ++ l++++v++ +ln +  +K+ lfg+ R  P              
  gi|1181030   859    VGIRLIWVAVIGDWLNLV--FKWiLFGE-R--P-------------- 886  

                CS GGHHHHHHCHHCHCCCHHCCHH HHT-- SS-B--TTCSSTTBS-SS-SS
                   csdlwyeellgyefycmagspg.ldrid.lfgsvlltsafalvseagpSF
                                      +++ +++++ +++s +  ++f+l++e+gp+ 
  gi|1181030   887 -------------------YWWvHETDYySNASAPAIQQFPLTCETGPG- 916  

                CS S-HHHHHHHHHHHHHHHHCTT                 SSCCC- CGS-E
                   PSGHaafaaafalflalylpr.................rlsklg.rllrl
                                    + pr+++++ +  ++++    +  ++  r l+ 
  gi|1181030   917 -----------------RDPRsdksgwhfvqgprilvlMELSTPcRILWA 949  

                CS ECHHHHCCHHHHHHHHHHHCTSS-HHHHCHHHCHCHCCCCHCHCHCCCGB
                   llgllllllallvglSRvylgvHypsDVlaGallGaliaalvllfvrrll
                   +l+  ++++ ++v+lSR++  +H+p++V+aG++ G+++a+ +++++  + 
  gi|1181030   950 MLWTGFWAVQVCVCLSRIFIAAHFPHQVIAGVISGMAVAETFQHIHSIYH 999  

                CS -   
                   d<-*
                   +   
  gi|1181030  1000 A    1000 

Cu_amine_oxidN3: domain 1 of 1, from 161 to 258: score 52.9, E = 1.3e-12
                CS    S---HHHHHHHHHHHHHTTGHHHHHHHHHTT.TCCGGGGEEEEEEE-
                   *->PpvtleEfasaeevplrrtdPefiealkkRGflvnglsdvvciPwtv
                      + vt +E+a + e++  +++  + ++l++++   +  ++  ++++t 
  gi|1181030   161    RAVTGAEYAAINELIQ-KELRKAPRFLAACC--AS--DGTDLATITT 202  

                CS SSSSTST.GTTS-EEEEEEEE-SSTT...S-GGGSEECTEEEEEETTTTE
                   GwfGeasleeGrRllkalcfyrdgtvsPmdnyyahPieGLeilvDldakk
                   +++G +s   G+R++++++f+ + ++    +y++ P++ Le+lv +  ++
  gi|1181030   203 APRGLKS---GDRTTWFVLFHGIAGS----GYFVLPVG-LEVLVEHGPLD 244  

                CS EEEEEEECCEETTE   
                   VieitDrgvripvp<-*
                   V  +   +v+++++   
  gi|1181030   245 VSQWYLCQVFYNGR    258  

DUF1965: domain 1 of 1, from 226 to 290: score -8.7, E = 0.051
                CS    SS-GGG-EEEEEEEEE--SS-GGG-EEEEEEETTEEESSHHHHHHHH
                   *->FDaetLlPlGLYfksDvTGRDpSkWkLlGwLYNdkfYtttEEFReAy
                        +   lP GL    +    D+S+W L    YN+ ++ +  E+  A+
  gi|1181030   226    --GYFVLPVGLEVLVEHGPLDVSQWYLCQVFYNGRYFPSIAELENAF 270  

                CS HSTT----.----TT--GGG--S--TTS--   
                   wspgFvklkPnvdvdnGdWavtdqnGdvpp<-*
                     +  +     v        +  q + v+    
  gi|1181030   271 VTKSLKVV---VV-------QKPQEDTVLG    290  
