Production of a New Thiopeptide Antibiotic, TP-1161, by a Marine Nocardiopsis Species -- Engelhardt et al. 76 (15): 4969 Data Supplement - Supplemental material -- Applied and Environmental Microbiology

Production of a New Thiopeptide Antibiotic, TP-1161, by a Marine Nocardiopsis Species
Appl. Environ. Microbiol. Engelhardt et al. 76: 4969

Supplemental material

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Supplemental file 1 - Supplemental Materials and Methods; neighbor-joining tree based on 16S rRNA gene sequences depicting the evolutionary relationships of 27 marine-derived actinomycetes and closely related taxa, including closest type strains (Fig. S1); LC-DAD isoplot and MS-TOF spectrum of thiopeptide antibiotic TP-1161 purified from Nocardiopsis sp. isolate TFS65-07 fermentation broth by preparative HPLC (Fig. S2); description of sediment samples (Table S1) and sponge samples (Table S2) taken from the Trondheim Fjord, Norway; methods used in the study for selective enrichment of actinobacteria and selected actinomycete genera (Table S3); bacterial and fungal test strains used in this study in agar diffusion assays and automated bioassays to identify actinomycete fermentation extracts with antibacterial/antifungal activities (Table S4); and NMR data for TP-1161 at 500 MHz (¹H) and 125 MHz (¹³C) in DMSO-d6 (Table S5).
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