tf p.value term.size query.size overlap.size term.id domain term.name adr1 1.54e-05 22 94 5 GO:0055114 BP oxidation reduction adr1 1.54e-05 22 94 5 GO:0022900 BP electron transport chain adr1 1.54e-05 22 94 5 GO:0022904 BP respiratory electron transport chain adr1 8.93e-05 31 94 5 GO:0006119 BP oxidative phosphorylation adr1 1.54e-05 22 94 5 GO:0042773 BP ATP synthesis coupled electron transport adr1 1.54e-05 22 94 5 GO:0042775 BP mitochondrial ATP synthesis coupled electron transport adr1 1.84e-06 26 94 6 GO:0070469 CC respiratory chain adr1 1.56e-05 99 94 9 GO:0044455 CC mitochondrial membrane part adr1 1.84e-06 26 94 6 GO:0005746 CC mitochondrial respiratory chain adr1 1.91e-06 99 94 10 GO:0015075 MF ion transmembrane transporter activity adr1 4.85e-06 86 94 9 GO:0008324 MF cation transmembrane transporter activity adr1 1.7e-06 76 94 9 GO:0022890 MF inorganic cation transmembrane transporter activity adr1 2.23e-05 39 94 6 GO:0015077 MF monovalent inorganic cation transmembrane transporter activity adr1 1.38e-05 36 94 6 GO:0015078 MF hydrogen ion transmembrane transporter activity adr1 6.36e-05 244 94 13 GO:0022892 MF substrate-specific transporter activity adr1 0.000335 76 94 7 KEGG:00190 ke Oxidative phosphorylation arg80 4.17e-08 22 304 10 GO:0055114 BP oxidation reduction arg80 4.17e-08 22 304 10 GO:0022900 BP electron transport chain arg80 4.17e-08 22 304 10 GO:0022904 BP respiratory electron transport chain arg80 2.42e-05 57 304 12 GO:0016310 BP phosphorylation arg80 1.61e-08 31 304 12 GO:0006119 BP oxidative phosphorylation arg80 4.17e-08 22 304 10 GO:0042773 BP ATP synthesis coupled electron transport arg80 4.17e-08 22 304 10 GO:0042775 BP mitochondrial ATP synthesis coupled electron transport arg80 7.14e-05 10 304 5 GO:0006123 BP mitochondrial electron transport, cytochrome c to oxygen arg80 5.38e-05 124 304 18 GO:0016072 BP rRNA metabolic process arg80 2.85e-07 26 304 10 GO:0070469 CC respiratory chain arg80 3.52e-05 335 304 35 GO:0031975 CC envelope arg80 3.52e-05 335 304 35 GO:0031967 CC organelle envelope arg80 1.27e-06 147 304 23 GO:0019866 CC organelle inner membrane arg80 2.37e-05 262 304 30 GO:0005740 CC mitochondrial envelope arg80 3.18e-06 225 304 29 GO:0031966 CC mitochondrial membrane arg80 9.21e-08 99 304 20 GO:0044455 CC mitochondrial membrane part arg80 5.28e-06 137 304 21 GO:0005743 CC mitochondrial inner membrane arg80 2.85e-07 26 304 10 GO:0005746 CC mitochondrial respiratory chain arg80 7.14e-05 10 304 5 GO:0016675 MF oxidoreductase activity, acting on heme group of donors arg80 7.14e-05 10 304 5 GO:0016676 MF oxidoreductase activity, acting on heme group of donors, oxygen as acceptor arg80 7.14e-05 10 304 5 GO:0015002 MF heme-copper terminal oxidase activity arg80 3.07e-07 39 304 12 GO:0015077 MF monovalent inorganic cation transmembrane transporter activity arg80 1.13e-07 36 304 12 GO:0015078 MF hydrogen ion transmembrane transporter activity arg80 7.14e-05 10 304 5 GO:0004129 MF cytochrome-c oxidase activity arg80 1.06e-07 76 304 18 KEGG:00190 ke Oxidative phosphorylation arg80 0.00051 8 304 4 REAC:504362 re Urea synthesis arg80 0.000158 11 304 5 REAC:504513 re Ornithine and proline metabolism arg80 2.18e-05 8 304 5 REAC:504512 re Ornithine metabolism arg81 4.51e-05 6 270 4 GO:0006591 BP ornithine metabolic process arg81 8.3e-05 29 270 7 KEGG:00330 ke Arginine and proline metabolism arg81 2.63e-06 11 270 6 REAC:504513 re Ornithine and proline metabolism arg81 0.000358 4 270 3 REAC:504676 re Proline catabolism arg81 8.39e-06 8 270 5 REAC:504512 re Ornithine metabolism arg81 0.000243 8 270 4 REAC:504362 re Urea synthesis arr1 2.51e-05 429 190 30 GO:0006950 BP response to stress arr1 0.000742 13 190 4 KEGG:00740 ke Riboflavin metabolism ash1 0.000178 49 199 7 REAC:504363 re Metabolism of amino acids ask10 0.00174 10 117 3 KEGG:00280 ke Valine, leucine and isoleucine degradation ask10 0.00024 13 117 4 KEGG:00740 ke Riboflavin metabolism bas1 1.43e-06 131 1024 43 GO:0044283 BP small molecule biosynthetic process bas1 4.51e-06 619 1024 140 GO:0044085 BP cellular component biogenesis bas1 4.63e-10 328 1024 96 GO:0022613 BP ribonucleoprotein complex biogenesis bas1 3.8e-11 306 1024 94 GO:0042254 BP ribosome biogenesis bas1 7.53e-06 60 1024 24 GO:0042255 BP ribosome assembly bas1 4.15e-06 51 1024 22 GO:0042257 BP ribosomal subunit assembly bas1 2.92e-06 11 1024 9 GO:0000786 CC nucleosome bas1 2.92e-06 11 1024 9 GO:0000788 CC nuclear nucleosome bas1 1.51e-28 142 1024 91 KEGG:03010 ke Ribosome bas1 1.06e-24 152 1024 95 REAC:504522 re 3' -UTR-mediated translational regulation bas1 1.06e-24 152 1024 95 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression bas1 9.98e-17 79 1024 55 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit bas1 1.76e-07 76 1024 41 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA bas1 2.57e-18 200 1024 104 REAC:504343 re Metabolism of proteins bas1 4.96e-11 259 1024 110 REAC:504459 re Gene Expression bas1 2.32e-23 164 1024 98 REAC:504507 re Translation bas1 2.49e-22 139 1024 87 REAC:504506 re Eukaryotic Translation Elongation bas1 2.49e-22 139 1024 87 REAC:504505 re Peptide chain elongation bas1 5.34e-23 137 1024 87 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site bas1 5.34e-23 137 1024 87 REAC:502806 re Hydrolysis of eEF1A:GTP bas1 1.09e-23 135 1024 87 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA bas1 2.49e-22 139 1024 87 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction bas1 6.35e-25 159 1024 98 REAC:504612 re Eukaryotic Translation Initiation bas1 6.35e-25 159 1024 98 REAC:504611 re Cap-dependent Translation Initiation bas1 2.39e-07 74 1024 40 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S bas1 2.39e-07 74 1024 40 REAC:504671 re Translation initiation complex formation bas1 1.44e-07 73 1024 40 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize bas1 2.39e-07 74 1024 40 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation bas1 6.31e-08 74 1024 41 REAC:504769 re Ribosomal scanning and start codon recognition bas1 1.44e-07 73 1024 40 REAC:503952 re Ribosomal scanning bas1 6.31e-08 74 1024 41 REAC:504040 re Start codon recognition bas1 2.12e-08 67 1024 39 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex bas1 2.12e-08 67 1024 39 REAC:502531 re Formation of the 43S pre-initiation complex bas1 2.43e-23 136 1024 87 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit bas1 2.43e-23 136 1024 87 REAC:504077 re The 60S subunit joins the translation initiation complex bas1 2.43e-23 136 1024 87 REAC:502286 re eIF5B:GTP is hydrolyzed and released bas1 3.35e-24 136 1024 88 REAC:504765 re Formation of a pool of free 40S subunits bas1 3.35e-24 136 1024 88 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome bdf2 1.33e-06 142 360 25 KEGG:03010 ke Ribosome bdf2 0.000284 200 360 27 REAC:504343 re Metabolism of proteins bdf2 0.00059 164 360 23 REAC:504507 re Translation bdf2 3.74e-05 139 360 23 REAC:504506 re Eukaryotic Translation Elongation bdf2 3.74e-05 139 360 23 REAC:504505 re Peptide chain elongation bdf2 2.89e-05 137 360 23 REAC:502806 re Hydrolysis of eEF1A:GTP bdf2 2.89e-05 137 360 23 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site bdf2 2.22e-05 135 360 23 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA bdf2 3.74e-05 139 360 23 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction bdf2 0.000361 159 360 23 REAC:504612 re Eukaryotic Translation Initiation bdf2 0.000361 159 360 23 REAC:504611 re Cap-dependent Translation Initiation bdf2 2.54e-05 136 360 23 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit bdf2 2.54e-05 136 360 23 REAC:504077 re The 60S subunit joins the translation initiation complex bdf2 2.54e-05 136 360 23 REAC:502286 re eIF5B:GTP is hydrolyzed and released bdf2 2.54e-05 136 360 23 REAC:504765 re Formation of a pool of free 40S subunits bdf2 2.54e-05 136 360 23 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome bdf2 0.000173 152 360 23 REAC:504522 re 3' -UTR-mediated translational regulation bdf2 0.000173 152 360 23 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression bdf2 0.00027 79 360 15 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit cac2 9.28e-06 456 548 67 GO:0044281 BP small molecule metabolic process cac2 5.38e-07 180 548 37 GO:0042180 BP cellular ketone metabolic process cac2 8.75e-07 176 548 36 GO:0006082 BP organic acid metabolic process cac2 8.75e-07 176 548 36 GO:0043436 BP oxoacid metabolic process cac2 8.75e-07 176 548 36 GO:0019752 BP carboxylic acid metabolic process cac2 7.08e-07 125 548 29 GO:0006519 BP cellular amino acid and derivative metabolic process cac2 4.17e-07 193 548 39 GO:0034641 BP cellular nitrogen compound metabolic process cac2 9.31e-07 113 548 27 GO:0044106 BP cellular amine metabolic process cac2 1.63e-07 98 548 26 GO:0006520 BP cellular amino acid metabolic process cac2 0.000799 33 548 10 KEGG:00620 ke Pyruvate metabolism cac2 0.000976 18 548 7 KEGG:00290 ke Valine, leucine and isoleucine biosynthesis cac2 4.77e-05 16 548 8 KEGG:00380 ke Tryptophan metabolism cac2 0.000353 47 548 13 KEGG:00010 ke Glycolysis / Gluconeogenesis cac2 0.00145 10 548 5 KEGG:00280 ke Valine, leucine and isoleucine degradation cac2 0.00195 15 548 6 KEGG:00340 ke Histidine metabolism cac2 0.000245 29 548 10 KEGG:00330 ke Arginine and proline metabolism cac2 3.07e-06 616 548 87 KEGG:01100 ke Metabolic pathways cac2 6.28e-06 49 548 15 REAC:504363 re Metabolism of amino acids cac2 0.000766 6 548 4 REAC:504501 re Aspartate, asparagine, glutamate, and glutamine metabolism cac2 0.000225 8 548 5 REAC:504416 re Synaptic Transmission cac2 0.000225 8 548 5 REAC:504415 re Transmission across Chemical Synapses cad1 5.59e-05 19 304 6 GO:0045259 CC proton-transporting ATP synthase complex cad1 4.41e-05 147 304 17 GO:0019866 CC organelle inner membrane cad1 6.85e-06 262 304 26 GO:0005740 CC mitochondrial envelope cad1 4.68e-05 225 304 22 GO:0031966 CC mitochondrial membrane cad1 4.76e-06 99 304 15 GO:0044455 CC mitochondrial membrane part cad1 1.74e-05 137 304 17 GO:0005743 CC mitochondrial inner membrane cad1 5.59e-05 19 304 6 GO:0005753 CC mitochondrial proton-transporting ATP synthase complex cad1 1.45e-06 39 304 10 GO:0015077 MF monovalent inorganic cation transmembrane transporter activity cad1 6.42e-07 36 304 10 GO:0015078 MF hydrogen ion transmembrane transporter activity cad1 3.76e-05 76 304 14 KEGG:00190 ke Oxidative phosphorylation cad1 1.73e-07 142 304 24 KEGG:03010 ke Ribosome cad1 2.52e-05 152 304 23 REAC:504522 re 3' -UTR-mediated translational regulation cad1 2.52e-05 152 304 23 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression cad1 0.000198 76 304 14 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA cad1 3.07e-05 200 304 27 REAC:504343 re Metabolism of proteins cad1 0.000564 259 304 29 REAC:504459 re Gene Expression cad1 2.78e-05 164 304 24 REAC:504507 re Translation cad1 1.14e-06 139 304 24 REAC:504506 re Eukaryotic Translation Elongation cad1 1.14e-06 139 304 24 REAC:504505 re Peptide chain elongation cad1 3.73e-06 137 304 23 REAC:502806 re Hydrolysis of eEF1A:GTP cad1 3.73e-06 137 304 23 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site cad1 2.82e-06 135 304 23 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA cad1 1.14e-06 139 304 24 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction cad1 5.59e-05 159 304 23 REAC:504612 re Eukaryotic Translation Initiation cad1 5.59e-05 159 304 23 REAC:504611 re Cap-dependent Translation Initiation cad1 0.000583 74 304 13 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S cad1 0.000583 74 304 13 REAC:504671 re Translation initiation complex formation cad1 0.000506 73 304 13 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize cad1 0.000583 74 304 13 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation cad1 0.000203 67 304 13 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex cad1 0.000203 67 304 13 REAC:502531 re Formation of the 43S pre-initiation complex cad1 0.000583 74 304 13 REAC:504769 re Ribosomal scanning and start codon recognition cad1 0.000506 73 304 13 REAC:503952 re Ribosomal scanning cad1 0.000583 74 304 13 REAC:504040 re Start codon recognition cad1 3.25e-06 136 304 23 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit cad1 3.25e-06 136 304 23 REAC:504077 re The 60S subunit joins the translation initiation complex cad1 3.25e-06 136 304 23 REAC:502286 re eIF5B:GTP is hydrolyzed and released cad1 3.25e-06 136 304 23 REAC:504765 re Formation of a pool of free 40S subunits cad1 3.25e-06 136 304 23 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome cbf1 1.63e-05 456 548 70 GO:0044281 BP small molecule metabolic process cbf1 2.91e-06 131 548 30 GO:0044283 BP small molecule biosynthetic process cbf1 8.64e-06 180 548 36 GO:0042180 BP cellular ketone metabolic process cbf1 4.74e-05 69 548 18 GO:0044282 BP small molecule catabolic process cbf1 1.32e-05 176 548 35 GO:0006082 BP organic acid metabolic process cbf1 1.32e-05 176 548 35 GO:0043436 BP oxoacid metabolic process cbf1 1.32e-05 176 548 35 GO:0019752 BP carboxylic acid metabolic process cbf1 3.06e-07 125 548 31 GO:0006519 BP cellular amino acid and derivative metabolic process cbf1 7.11e-06 193 548 38 GO:0034641 BP cellular nitrogen compound metabolic process cbf1 3.92e-06 113 548 27 GO:0044106 BP cellular amine metabolic process cbf1 1.84e-07 98 548 27 GO:0006520 BP cellular amino acid metabolic process cbf1 1.1e-06 65 548 20 GO:0016053 BP organic acid biosynthetic process cbf1 1.1e-06 65 548 20 GO:0046394 BP carboxylic acid biosynthetic process cbf1 3.07e-05 92 548 22 GO:0044271 BP cellular nitrogen compound biosynthetic process cbf1 6.64e-06 55 548 17 GO:0009309 BP amine biosynthetic process cbf1 1.5e-06 50 548 17 GO:0008652 BP cellular amino acid biosynthetic process cbf1 1.93e-05 23 548 10 GO:0009310 BP amine catabolic process cbf1 0.000114 13 548 7 KEGG:00300 ke Lysine biosynthesis cbf1 0.000357 15 548 7 KEGG:00340 ke Histidine metabolism crz1 1.38e-05 11 183 5 GO:0000786 CC nucleosome crz1 1.38e-05 11 183 5 GO:0000788 CC nuclear nucleosome cse2 3.09e-05 190 775 45 GO:0034470 BP ncRNA processing cse2 9.36e-06 193 775 47 GO:0034641 BP cellular nitrogen compound metabolic process cse2 4.87e-09 328 775 80 GO:0022613 BP ribonucleoprotein complex biogenesis cse2 5.22e-09 306 775 76 GO:0042254 BP ribosome biogenesis cse2 7.82e-06 203 775 49 GO:0034660 BP ncRNA metabolic process cse2 2.69e-05 456 775 89 GO:0044281 BP small molecule metabolic process cse2 0.00105 28 775 11 KEGG:00030 ke Pentose phosphate pathway cse2 5.33e-07 616 775 123 KEGG:01100 ke Metabolic pathways cse2 0.000349 29 775 12 KEGG:00270 ke Cysteine and methionine metabolism cse2 0.00148 29 775 11 KEGG:00330 ke Arginine and proline metabolism cse2 0.000233 12 775 7 REAC:504417 re Pentose phosphate pathway (hexose monophosphate shunt) cup2 1.42e-05 99 423 20 GO:0044455 CC mitochondrial membrane part cup2 6.95e-05 262 423 36 GO:0005740 CC mitochondrial envelope cup2 0.00024 76 423 13 KEGG:00190 ke Oxidative phosphorylation dal80 0.000462 13 106 3 KEGG:00740 ke Riboflavin metabolism dal82 2.64e-05 60 675 18 GO:0042255 BP ribosome assembly dal82 7.47e-05 33 675 12 GO:0016469 CC proton-transporting two-sector ATPase complex dal82 5.32e-05 19 675 9 GO:0045259 CC proton-transporting ATP synthase complex dal82 5.32e-05 19 675 9 GO:0005753 CC mitochondrial proton-transporting ATP synthase complex dal82 3.16e-06 18 675 10 GO:0033177 CC proton-transporting two-sector ATPase complex, proton-transporting domain dal82 1.81e-06 11 675 8 GO:0045263 CC proton-transporting ATP synthase complex, coupling factor F(o) dal82 1.81e-06 11 675 8 GO:0000276 CC mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) dal82 1.03e-36 142 675 79 KEGG:03010 ke Ribosome dal82 4.41e-25 152 675 77 REAC:504522 re 3' -UTR-mediated translational regulation dal82 4.41e-25 152 675 77 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression dal82 4.32e-21 79 675 50 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit dal82 1.43e-05 76 675 29 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA dal82 5.06e-19 200 675 82 REAC:504343 re Metabolism of proteins dal82 2.15e-12 259 675 85 REAC:504459 re Gene Expression dal82 3.18e-22 164 675 77 REAC:504507 re Translation dal82 1.14e-28 139 675 77 REAC:504506 re Eukaryotic Translation Elongation dal82 1.14e-28 139 675 77 REAC:504505 re Peptide chain elongation dal82 2.82e-29 137 675 77 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site dal82 2.82e-29 137 675 77 REAC:502806 re Hydrolysis of eEF1A:GTP dal82 6.74e-30 135 675 77 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA dal82 1.14e-28 139 675 77 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction dal82 2.28e-23 159 675 77 REAC:504612 re Eukaryotic Translation Initiation dal82 2.28e-23 159 675 77 REAC:504611 re Cap-dependent Translation Initiation dal82 7.77e-05 74 675 27 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S dal82 7.77e-05 74 675 27 REAC:504671 re Translation initiation complex formation dal82 5.85e-05 73 675 27 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize dal82 7.77e-05 74 675 27 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation dal82 7.77e-05 74 675 27 REAC:504769 re Ribosomal scanning and start codon recognition dal82 5.85e-05 73 675 27 REAC:503952 re Ribosomal scanning dal82 7.77e-05 74 675 27 REAC:504040 re Start codon recognition dal82 8.92e-06 67 675 27 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex dal82 8.92e-06 67 675 27 REAC:502531 re Formation of the 43S pre-initiation complex dal82 1.39e-29 136 675 77 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit dal82 1.39e-29 136 675 77 REAC:504077 re The 60S subunit joins the translation initiation complex dal82 1.39e-29 136 675 77 REAC:502286 re eIF5B:GTP is hydrolyzed and released dal82 1.39e-29 136 675 77 REAC:504765 re Formation of a pool of free 40S subunits dal82 1.39e-29 136 675 77 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome dat1 0.00106 13 213 4 KEGG:00740 ke Riboflavin metabolism dig1 2.62e-05 21 280 7 GO:0006891 BP intra-Golgi vesicle-mediated transport dig1 4.43e-06 128 280 19 GO:0051704 BP multi-organism process dig1 7.28e-07 114 280 19 GO:0000746 BP conjugation dig1 3.77e-05 215 280 24 GO:0019953 BP sexual reproduction dig1 7.28e-07 114 280 19 GO:0000747 BP conjugation with cellular fusion dig1 5.92e-05 59 280 11 GO:0032993 CC protein-DNA complex dig1 2.55e-09 11 280 8 GO:0000786 CC nucleosome dig1 2.55e-09 11 280 8 GO:0000788 CC nuclear nucleosome dig1 0.00012 13 280 6 KEGG:00740 ke Riboflavin metabolism dig1 0.00133 142 280 20 KEGG:03010 ke Ribosome dig1 1.5e-05 152 280 22 REAC:504522 re 3' -UTR-mediated translational regulation dig1 1.5e-05 152 280 22 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression dig1 0.000147 200 280 24 REAC:504343 re Metabolism of proteins dig1 0.000192 259 280 28 REAC:504459 re Gene Expression dig1 5.56e-05 164 280 22 REAC:504507 re Translation dig1 0.000183 139 280 19 REAC:504506 re Eukaryotic Translation Elongation dig1 0.000183 139 280 19 REAC:504505 re Peptide chain elongation dig1 0.000149 137 280 19 REAC:502806 re Hydrolysis of eEF1A:GTP dig1 0.000149 137 280 19 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site dig1 0.00012 135 280 19 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA dig1 0.000183 139 280 19 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction dig1 3.28e-05 159 280 22 REAC:504612 re Eukaryotic Translation Initiation dig1 3.28e-05 159 280 22 REAC:504611 re Cap-dependent Translation Initiation dig1 0.000134 136 280 19 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit dig1 0.000134 136 280 19 REAC:504077 re The 60S subunit joins the translation initiation complex dig1 0.000134 136 280 19 REAC:502286 re eIF5B:GTP is hydrolyzed and released dig1 3.6e-05 136 280 20 REAC:504765 re Formation of a pool of free 40S subunits dig1 3.6e-05 136 280 20 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome dot6 0.000501 13 158 4 KEGG:00920 ke Sulfur metabolism ecm22 2.81e-05 14 195 5 GO:0006694 BP steroid biosynthetic process ecm22 2.81e-05 14 195 5 GO:0016126 BP sterol biosynthetic process fkh2 4.76e-05 32 406 10 GO:0000466 BP maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) fkh2 1.3e-05 1690 406 158 GO:0043170 BP macromolecule metabolic process fkh2 8.33e-09 625 406 82 GO:0010467 BP gene expression fkh2 1.77e-13 619 406 93 GO:0044085 BP cellular component biogenesis fkh2 6.31e-05 171 406 27 GO:0034622 BP cellular macromolecular complex assembly fkh2 2.26e-05 1353 406 131 GO:0006807 BP nitrogen compound metabolic process fkh2 2.54e-05 1550 406 146 GO:0044260 BP cellular macromolecule metabolic process fkh2 5.1e-22 328 406 76 GO:0022613 BP ribonucleoprotein complex biogenesis fkh2 6.14e-22 306 406 73 GO:0042254 BP ribosome biogenesis fkh2 6.6e-07 61 406 17 GO:0042273 BP ribosomal large subunit biogenesis fkh2 1.3e-05 82 406 18 GO:0022618 BP ribonucleoprotein complex assembly fkh2 7.31e-07 1101 406 117 GO:0006139 BP cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolic process fkh2 1.56e-13 558 406 87 GO:0016070 BP cellular RNA metabolic process fkh2 1.08e-15 203 406 50 GO:0034660 BP ncRNA metabolic process fkh2 4e-13 124 406 35 GO:0016072 BP rRNA metabolic process fkh2 1.57e-08 337 406 53 GO:0006396 BP RNA processing fkh2 3.44e-14 190 406 46 GO:0034470 BP ncRNA processing fkh2 6.61e-12 115 406 32 GO:0006364 BP rRNA processing fkh2 1.32e-05 60 406 15 GO:0042255 BP ribosome assembly fkh2 7.58e-09 64 406 20 GO:0006401 BP RNA catabolic process fkh2 5.67e-07 54 406 16 GO:0006402 BP mRNA catabolic process fkh2 1.29e-05 53 406 14 GO:0030684 CC preribosome fkh2 3.17e-06 8 406 6 GO:0030687 CC preribosome, large subunit precursor fkh2 6.53e-08 631 406 80 GO:0031974 CC membrane-enclosed lumen fkh2 1.24e-08 598 406 79 GO:0043233 CC organelle lumen fkh2 1.24e-08 598 406 79 GO:0070013 CC intracellular organelle lumen fkh2 1.59e-07 1169 406 125 GO:0005634 CC nucleus fkh2 1.36e-07 833 406 97 GO:0044428 CC nuclear part fkh2 6.61e-13 427 406 72 GO:0031981 CC nuclear lumen fkh2 2.69e-17 208 406 53 GO:0005730 CC nucleolus fkh2 0.000885 8 406 4 KEGG:00790 ke Folate biosynthesis fkh2 1.94e-05 55 406 13 KEGG:03018 ke RNA degradation fzf1 8.44e-05 24 114 5 GO:0005484 MF SNAP receptor activity fzf1 5.1e-05 23 114 5 KEGG:04130 ke SNARE interactions in vesicular transport gal3 3.99e-06 60 83 8 GO:0055066 BP di-, tri-valent inorganic cation homeostasis gal3 1.58e-05 35 83 6 GO:0055072 BP iron ion homeostasis gal3 7.68e-05 6 83 3 GO:0015688 BP iron chelate transport gal3 3.99e-06 60 83 8 GO:0030005 BP cellular di-, tri-valent inorganic cation homeostasis gal3 1.58e-05 35 83 6 GO:0006879 BP cellular iron ion homeostasis gal3 4.09e-06 8 83 4 GO:0033212 BP iron assimilation gal3 7.68e-05 6 83 3 GO:0033214 BP iron assimilation by chelation and transport gal3 7.68e-05 6 83 3 GO:0015892 BP siderophore-iron transport gal80 2.08e-07 5 84 4 GO:0006012 BP galactose metabolic process gal80 3e-06 3 84 3 GO:0019388 BP galactose catabolic process gal80 0.000304 3 84 2 REAC:504537 re Galactose catabolism gcr2 4.94e-06 22 839 12 GO:0055114 BP oxidation reduction gcr2 4.94e-06 22 839 12 GO:0022900 BP electron transport chain gcr2 4.94e-06 22 839 12 GO:0022904 BP respiratory electron transport chain gcr2 7.35e-05 31 839 13 GO:0006119 BP oxidative phosphorylation gcr2 4.94e-06 22 839 12 GO:0042773 BP ATP synthesis coupled electron transport gcr2 4.94e-06 22 839 12 GO:0042775 BP mitochondrial ATP synthesis coupled electron transport gcr2 1.66e-06 456 839 95 GO:0044281 BP small molecule metabolic process gcr2 3.42e-10 131 839 45 GO:0044283 BP small molecule biosynthetic process gcr2 4.85e-06 180 839 46 GO:0042180 BP cellular ketone metabolic process gcr2 6.08e-06 176 839 45 GO:0006082 BP organic acid metabolic process gcr2 6.08e-06 176 839 45 GO:0043436 BP oxoacid metabolic process gcr2 6.08e-06 176 839 45 GO:0019752 BP carboxylic acid metabolic process gcr2 5.15e-05 79 839 24 GO:0032787 BP monocarboxylic acid metabolic process gcr2 2.74e-06 18 839 11 GO:0006090 BP pyruvate metabolic process gcr2 8.47e-05 133 839 34 GO:0006066 BP alcohol metabolic process gcr2 1.13e-06 23 839 13 GO:0046165 BP alcohol biosynthetic process gcr2 2.89e-05 15 839 9 GO:0046364 BP monosaccharide biosynthetic process gcr2 1.85e-06 12 839 9 GO:0019319 BP hexose biosynthetic process gcr2 2.88e-05 58 839 20 GO:0006006 BP glucose metabolic process gcr2 1.08e-07 10 839 9 GO:0006094 BP gluconeogenesis gcr2 5.95e-05 70 839 22 GO:0070925 BP organelle assembly gcr2 1.46e-10 328 839 85 GO:0022613 BP ribonucleoprotein complex biogenesis gcr2 2.63e-12 306 839 85 GO:0042254 BP ribosome biogenesis gcr2 3.62e-06 60 839 22 GO:0042255 BP ribosome assembly gcr2 3.01e-06 51 839 20 GO:0042257 BP ribosomal subunit assembly gcr2 6.17e-08 61 839 25 GO:0042273 BP ribosomal large subunit biogenesis gcr2 1.93e-06 38 839 17 GO:0000027 BP ribosomal large subunit assembly gcr2 7.02e-06 26 839 13 GO:0070469 CC respiratory chain gcr2 7.02e-06 26 839 13 GO:0005746 CC mitochondrial respiratory chain gcr2 2.43e-05 53 839 19 GO:0030684 CC preribosome gcr2 9.68e-05 40 839 15 GO:0032040 CC small-subunit processome gcr2 2.65e-05 208 839 49 GO:0005730 CC nucleolus gcr2 2.98e-06 91 839 29 GO:0016491 MF oxidoreductase activity gcr2 5.89e-05 10 839 7 GO:0016675 MF oxidoreductase activity, acting on heme group of donors gcr2 5.89e-05 10 839 7 GO:0016676 MF oxidoreductase activity, acting on heme group of donors, oxygen as acceptor gcr2 5.89e-05 10 839 7 GO:0015002 MF heme-copper terminal oxidase activity gcr2 5.89e-05 10 839 7 GO:0004129 MF cytochrome-c oxidase activity gcr2 5.33e-07 47 839 23 KEGG:00010 ke Glycolysis / Gluconeogenesis gcr2 1.73e-11 142 839 57 KEGG:03010 ke Ribosome gcr2 0.11 3 839 2 REAC:504409 re Synthesis of bile acids and bile salts via 27-hydroxycholesterol gcr2 0.11 3 839 2 REAC:499821 re 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one gcr2 0.11 3 839 2 REAC:499823 re 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one gcr2 0.371 2 839 1 REAC:503313 re ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde gcr2 0.11 3 839 2 REAC:499819 re 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one gcr2 0.371 2 839 1 REAC:504236 re uridine 5'-triphosphate + glutamine + ATP + H2O => cytidine 5'-triphosphate + glutamate + ADP + orthophosphate gcr2 0.207 1 839 1 REAC:504181 re tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate gcr2 0.207 1 839 1 REAC:504473 re Formation of PAPS gcr2 0.207 1 839 1 REAC:501387 re ATP + sulfate => adenylyl sulfate (APS) + pyrophosphate gcr2 0.207 1 839 1 REAC:500422 re adenylyl sulfate (APS) + ATP => PAPS + ADP gcr2 0.207 1 839 1 REAC:504699 re Conversion of cytosolic inosine 5'-monophosphate, L-aspartate, and GTP to adenylosuccinate, guanosine 5'-diphosphate, and orthophosphate gcr2 0.207 1 839 1 REAC:502896 re inosine 5'-monophosphate + L-aspartate + GTP => adenylosuccinate + guanosine 5'-diphosphate + orthophosphate gcr2 0.207 1 839 1 REAC:500122 re Activation of Cdc25a (string) by E2F1 gcr2 0.191 4 839 2 REAC:504401 re Synthesis of bile acids and bile salts via 24-hydroxycholesterol gcr2 0.11 3 839 2 REAC:499822 re 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one gcr2 0.11 3 839 2 REAC:499820 re 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one gcr2 0.207 1 839 1 REAC:504034 re Squalene 2,3-epoxide cyclizes, forming lanosterol gcr2 0.207 1 839 1 REAC:501085 re asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate gcr2 0.371 2 839 1 REAC:504768 re Intrinsic Pathway for Apoptosis gcr2 0.371 2 839 1 REAC:504767 re Release of apoptotic factors from the mitochondria gcr2 0.371 2 839 1 REAC:503892 re Release of Cytochrome c from mitochondria gcr2 0.207 1 839 1 REAC:503652 re propionyl-CoA + carnitine => propionylcarnitine + CoASH gcr2 0.371 2 839 1 REAC:504741 re Activation of ATR in response to replication stress gcr2 0.371 2 839 1 REAC:503499 re Phosphorylation of Cdc25A at Ser-123 by Chk1 gcr2 0.11 3 839 2 REAC:503841 re Reduction of isocaproaldehyde to 4-methylpentan-1-ol gcr2 0.371 2 839 1 REAC:503501 re Phosphorylation of Cdc25A at Ser-123 by Chk2 gcr2 0.207 1 839 1 REAC:499831 re 4-methylcholesta-8(9), 24-dien-3-one is reduced to 4-methylcholesta-8(9), 24-dien-3beta-ol gcr2 0.458 45 839 10 REAC:504346 re Metablism of nucleotides gcr2 0.392 29 839 7 REAC:504367 re Purine metabolism gcr2 0.148 18 839 6 REAC:504376 re Purine biosynthesis gcr2 0.0296 4 839 3 REAC:504698 re Conversion of cytosolic inosine 5'-monophosphate (IMP), NAD+, and H2O to xanthosine 5'-monophosphate (XMP) and NADH + H+ gcr2 0.0296 4 839 3 REAC:502889 re inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+ gcr2 0.207 1 839 1 REAC:504324 re xanthosine 5'-monophosphate (XMP) + L-glutamine + ATP + H2O => guanosine 5'-monophosphate (GMP) + L-glutamate + adenosine 5'-monophosphate (AMP) + pyrophosphate gcr2 0.207 1 839 1 REAC:504378 re Reversible phosphorylation of nucleoside diphosphates gcr2 0.207 1 839 1 REAC:504380 re Reversible phosphorylation of cytosolic nucleoside diphosphates by nucleoside diphosphate kinase B hexamer gcr2 0.207 1 839 1 REAC:504382 re Reversible phosphorylation of mitochondrial nucleoside diphosphates by nucleoside diphosphate kinase D, mitochondrial hexamer gcr2 0.207 1 839 1 REAC:499590 re 2'-deoxyadenosine 5'-diphosphate (dADP) + ATP <=> dATP + adenosine 5'-diphosphate (ADP) gcr2 0.207 1 839 1 REAC:500339 re adenosine 5'-diphosphate (ADP) + CTP <=> ATP + cytidine 5'-diphosphate (CDP) gcr2 0.207 1 839 1 REAC:500348 re adenosine 5'-diphosphate (ADP) + GTP <=> ATP + guanosine 5'-diphosphate (GDP) gcr2 0.207 1 839 1 REAC:502763 re guanosine 5'-diphosphate (GDP) + ATP <=> GTP + adenosine 5'-diphosphate (ADP) gcr2 0.207 1 839 1 REAC:499599 re 2'-deoxycytidine 5'-diphosphate (dCDP) + ATP <=> dCTP + adenosine 5'-diphosphate (ADP) gcr2 0.207 1 839 1 REAC:500350 re adenosine 5'-diphosphate (ADP) + TTP <=> ATP + thymidine 5'-diphosphate (TDP) gcr2 0.207 1 839 1 REAC:500345 re adenosine 5'-diphosphate (ADP) + dGTP <=> ATP + 2'-deoxyguanosine 5'-diphosphate (dGDP) gcr2 0.207 1 839 1 REAC:501881 re cytidine 5'-diphosphate (CDP) + ATP <=> CTP + adenosine 5'-diphosphate (ADP) gcr2 0.207 1 839 1 REAC:500341 re adenosine 5'-diphosphate (ADP) + dATP <=> ATP + 2'-deoxyadenosine 5'-diphosphate (dADP) gcr2 0.207 1 839 1 REAC:500343 re adenosine 5'-diphosphate (ADP) + dCTP <=> ATP + 2'-deoxycytidine 5'-diphosphate (dCDP) gcr2 0.207 1 839 1 REAC:499615 re 2'-deoxyguanosine 5'-diphosphate (dGDP) + ATP <=> dGTP + adenosine 5'-diphosphate (ADP) gcr2 0.207 1 839 1 REAC:500346 re adenosine 5'-diphosphate (ADP) + dUTP <=> ATP + 2'-deoxyuridine 5'-diphosphate (dUDP) gcr2 0.207 1 839 1 REAC:504221 re uridine 5'-diphosphate (UDP) + ATP <=> UTP + adenosine 5'-diphosphate (ADP) gcr2 0.207 1 839 1 REAC:504110 re thymidine 5'-diphosphate (TDP) + ATP <=> TTP + adenosine 5'-diphosphate (ADP) gcr2 0.207 1 839 1 REAC:500352 re adenosine 5'-diphosphate (ADP) + UTP <=> ATP + uridine 5'-diphosphate (UDP) gcr2 0.207 1 839 1 REAC:499624 re 2'-deoxyuridine 5'-diphosphate (dUDP) + ATP <=> dUTP + adenosine 5'-diphosphate (ADP) gcr2 0.207 1 839 1 REAC:504379 re Reversible phosphorylation of cytosolic nucleoside diphosphates by nucleoside diphosphate kinase A hexamer gcr2 0.207 1 839 1 REAC:504381 re Reversible phosphorylation of cytosolic nucleoside diphosphates by nucleoside diphosphate kinase C hexamer gcr2 0.207 1 839 1 REAC:504377 re Reversible phosphorylation of cytosolic nucleoside diphosphates by nucleoside diphosphate kinase A,B heterohexamer gcr2 0.207 1 839 1 REAC:502762 re guanosine 5'-diphosphate (GDP) + ATP <=> GTP + adenosine 5'-diphosphate (ADP) gcr2 0.207 1 839 1 REAC:500340 re adenosine 5'-diphosphate (ADP) + dATP <=> ATP + 2'-deoxyadenosine 5'-diphosphate (dADP) gcr2 0.207 1 839 1 REAC:500344 re adenosine 5'-diphosphate (ADP) + dGTP <=> ATP + 2'-deoxyguanosine 5'-diphosphate (dGDP) gcr2 0.207 1 839 1 REAC:500347 re adenosine 5'-diphosphate (ADP) + GTP <=> ATP + guanosine 5'-diphosphate (GDP) gcr2 0.207 1 839 1 REAC:500351 re adenosine 5'-diphosphate (ADP) + UTP <=> ATP + uridine 5'-diphosphate (UDP) gcr2 0.207 1 839 1 REAC:504109 re thymidine 5'-diphosphate (TDP) + ATP <=> thymidine 5'-triphosphate (TTP) + ADP gcr2 0.207 1 839 1 REAC:500342 re adenosine 5'-diphosphate (ADP) + dCTP <=> ATP + 2'-deoxycytidine 5'-diphosphate (dCDP) gcr2 0.207 1 839 1 REAC:499623 re 2'-deoxyuridine 5'-diphosphate (dUDP) + ATP <=> deoxyuridine 5'-triphosphate (dUTP) + ADP gcr2 0.207 1 839 1 REAC:500338 re adenosine 5'-diphosphate (ADP) + CTP <=> ATP + cytidine 5'-diphosphate (CDP) gcr2 0.207 1 839 1 REAC:500349 re adenosine 5'-diphosphate (ADP) + TTP <=> ATP + thymidine 5'-diphosphate (TDP) gcr2 0.207 1 839 1 REAC:499586 re 2'-deoxyadenosine 5'-diphosphate (dADP) + ATP <=> dATP + adenosine 5'-diphosphate (ADP) gcr2 0.207 1 839 1 REAC:499614 re 2'-deoxyguanosine 5'-diphosphate (dGDP) + ATP <=> dGTP + adenosine 5'-diphosphate (ADP) gcr2 0.371 2 839 1 REAC:504369 re Phosphorylation of nucleosides to form nucleoside 5'-monophosphates gcr2 0.207 1 839 1 REAC:504604 re Phosphorylation of cytosolic nucleosides by uridine-cytidine kinase 2 gcr2 0.207 1 839 1 REAC:501877 re cytidine + ATP => cytidine 5'-monophosphate (CMP) + ADP gcr2 0.207 1 839 1 REAC:504218 re uridine + ATP => uridine 5'-monophosphate (UMP) + ADP gcr2 0.207 1 839 1 REAC:499631 re 2'-deoxyuridine 5'-triphosphate (dUTP) + ADP <=> 2'-deoxyuridine 5'-diphosphate (dUDP) + ATP gcr2 0.207 1 839 1 REAC:504220 re uridine 5'-diphosphate (UDP) + ATP <=> uridine 5'-triphosphate (UTP) + ADP gcr2 0.207 1 839 1 REAC:499598 re 2'-deoxycytidine 5'-diphosphate (dCDP) + ATP <=> dCTP + adenosine 5'-diphosphate (ADP) gcr2 0.207 1 839 1 REAC:501880 re cytidine 5'-diphosphate (CDP) + ATP <=> CTP + adenosine 5'-diphosphate (ADP) gcr2 0.371 2 839 1 REAC:502634 re glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate gcr2 0.362 6 839 2 REAC:503052 re Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere gcr2 0.207 1 839 1 REAC:503743 re PTEN dephosphorylates PIP3 gcr2 0.11 3 839 2 REAC:499824 re 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one gcr2 0.207 1 839 1 REAC:504122 re Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX gcr2 0.207 1 839 1 REAC:504136 re Translocation of Cdc25 to the nucleus gcr2 0.207 1 839 1 REAC:504137 re Translocation of Cdc25B to the cytoplasm gcr2 0.0939 9 839 4 REAC:504431 re Triacylglyceride Biosynthesis gcr2 0.371 2 839 1 REAC:501785 re Conversion of Diacylglycerol to Triacylglycerol gcr2 0.0296 4 839 3 REAC:504593 re Conversion of Fatty Acyl-CoA to Phosphatidic Acid gcr2 0.11 3 839 2 REAC:504592 re Synthesis of lysophosphatidic acid from glycerol-3-phosphate gcr2 0.11 3 839 2 REAC:504591 re Formation of Cytosolic Glycerol-3-phosphate gcr2 0.0426 2 839 2 REAC:501793 re Conversion of Dihydroxyacetone Phosphate to Glycerol -3- phosphate gcr2 0.207 1 839 1 REAC:504717 re Synthesis of phosphatidic acid from lysophosphatidic acid gcr2 0.207 1 839 1 REAC:503096 re lysophosphatic acid + fatty acyl CoA => phosphatidic acid + CoA (1) gcr2 0.443 7 839 2 REAC:504504 re Post-chaperonin tubulin folding pathway gcr2 0.11 3 839 2 REAC:500648 re alpha-tubulin:GTP + Cofactor E -> alpha-tubulin:GTP:Cofactor E gcr2 0.191 4 839 2 REAC:500649 re alpha-tubulin:GTP:Cofactor B +Cofactor E -> alpha-tubulin:GTP: Cofactor E +Cofactor B gcr2 0.277 5 839 2 REAC:501426 re Beta-tubulin:GTP:Cofactor D+alpha-tubulin:GTP:Cofactor E-> Beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E gcr2 0.11 3 839 2 REAC:500644 re alpha-tubulin:GTP + Cofactor B -> alpha-tubulin:GTP: Cofactor B gcr2 0.371 2 839 1 REAC:501604 re Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 gcr2 0.371 2 839 1 REAC:502078 re Dephosphorylation of nuclear Cyclin A:phosph-Cdc2 complexes gcr2 0.371 2 839 1 REAC:500620 re alpha-D-Glucose 6-phosphate <=> D-Glucose 1-phosphate gcr2 0.443 7 839 2 REAC:504740 re S6K1 signalling gcr2 0.191 4 839 2 REAC:503582 re Phosphorylation of Ribosomal protein S6 by activated S6K1 gcr2 0.277 5 839 2 REAC:504486 re Metabolism of nitric oxide gcr2 0.277 5 839 2 REAC:504485 re eNOS activation and regulation gcr2 0.277 5 839 2 REAC:504484 re eNOS activation gcr2 0.277 5 839 2 REAC:500516 re Akt phosphorylates eNOS gcr2 0.277 5 839 2 REAC:503281 re NO biosynthesis gcr2 0.11 3 839 2 REAC:504680 re Glyoxylate metabolism gcr2 0.207 1 839 1 REAC:502726 re glycolate + O2 => glyoxylate + H2O2 gcr2 0.207 1 839 1 REAC:502736 re glyoxylate + NADPH + H+ => glycolate + NADP+ gcr2 0.207 1 839 1 REAC:502738 re glyoxylate + O2 => oxalate + H2O2 gcr2 0.371 2 839 1 REAC:504370 re Hypoxanthine formation gcr2 0.207 1 839 1 REAC:499577 re 2'-Deoxyadenosine + H2O => 2'-Deoxyinosine + NH3 gcr2 4.73e-05 48 839 22 REAC:504354 re Diabetes pathways gcr2 0.00305 65 839 23 REAC:504349 re Metabolism of carbohydrates gcr2 0.223 12 839 4 REAC:504417 re Pentose phosphate pathway (hexose monophosphate shunt) gcr2 0.207 1 839 1 REAC:503951 re ribose 5-phosphate <=> D-ribulose 5-phosphate gcr2 0.191 4 839 2 REAC:501939 re D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate gcr2 0.207 1 839 1 REAC:503994 re sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate gcr2 0.207 1 839 1 REAC:501974 re D-ribulose 5-phosphate <=> ribose 5-phosphate gcr2 0.207 1 839 1 REAC:501927 re D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate gcr2 0.000615 45 839 19 REAC:504348 re Glucose metabolism gcr2 1.11e-05 22 839 14 REAC:504355 re Gluconeogenesis gcr2 0.207 1 839 1 REAC:501928 re D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate gcr2 0.207 1 839 1 REAC:503148 re malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix] gcr2 0.207 1 839 1 REAC:501955 re D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate gcr2 0.00874 3 839 3 REAC:499530 re 1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+ gcr2 0.000362 5 839 5 REAC:503441 re Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate gcr2 0.207 1 839 1 REAC:501332 re ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate gcr2 0.207 1 839 1 REAC:499677 re 2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate gcr2 0.207 1 839 1 REAC:503332 re Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+ gcr2 0.191 4 839 2 REAC:504498 re Glucose uptake gcr2 0.191 4 839 2 REAC:504534 re Glucose + ATP => glucose-6-phosphate + ADP gcr2 0.191 4 839 2 REAC:501352 re ATP + alpha-D-Glucose => ADP + alpha-D-glucose 6-phosphate [hexokinase 1] gcr2 0.107 6 839 3 REAC:504683 re Regulation of beta-cell development gcr2 0.107 6 839 3 REAC:504682 re Regulation of gene expression in beta cells gcr2 0.191 4 839 2 REAC:503262 re NEUROD1- and PDX1-dependent synthesis of glucokinase (GCK) protein gcr2 0.179 23 839 7 REAC:504350 re Pyruvate metabolism and TCA cycle gcr2 0.00496 71 839 24 REAC:504353 re Integration of energy metabolism gcr2 0.362 6 839 2 REAC:504789 re ChREBP activates metabolic gene expression gcr2 0.371 2 839 1 REAC:504790 re Transcriptional activation of glucose metabolism genes by ChREBP:MLX gcr2 0.371 2 839 1 REAC:502784 re HNF1A-dependent synthesis of the L isoform of PKLR protein gcr2 4.73e-05 48 839 22 REAC:504352 re Glucose Regulation of Insulin Secretion gcr2 0.0628 5 839 3 REAC:504759 re Electron Transport Chain gcr2 0.0628 5 839 3 REAC:504130 re Transfer of electrons through the succinate dehydrogenase complex gcr2 0.191 4 839 2 REAC:501350 re ATP + alpha-D-Glucose => ADP + alpha-D-glucose 6-phosphate [glucokinase] gcr2 0.0765 19 839 7 REAC:504351 re Citric acid cycle (TCA cycle) gcr2 0.207 1 839 1 REAC:499514 re (S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ gcr2 0.0426 2 839 2 REAC:500059 re Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA gcr2 0.0628 5 839 3 REAC:504064 re Succinate <=> Fumarate (with FAD redox reaction on enzyme) gcr2 9.47e-07 17 839 13 REAC:504394 re Glycolysis gcr2 0.207 1 839 1 REAC:499788 re 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate gcr2 0.000362 5 839 5 REAC:499691 re 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O gcr2 0.207 1 839 1 REAC:504620 re Dihydroxyacetone phosphate is isomerized to form glyceraldehyde-3-phosphate gcr2 0.207 1 839 1 REAC:502123 re dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate gcr2 0.207 1 839 1 REAC:504474 re 1,3-bisphosphoglycerate and ADP react to form 3-phosphoglycerate and ATP gcr2 0.207 1 839 1 REAC:500427 re ADP + 3-Phospho-D-glyceroyl phosphate <=> ATP + 3-Phospho-D-glycerate gcr2 0.00874 3 839 3 REAC:504608 re Glyceraldehyde 3-phosphate, NAD+, and orthophosphate react to form 1,3-bisphosphoglycerate, NADH, and H+ gcr2 0.00874 3 839 3 REAC:501949 re D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ gcr2 0.371 2 839 1 REAC:504475 re Phosphoenolpyruvate and ADP react to form pyruvate and ATP gcr2 0.371 2 839 1 REAC:500442 re ADP + Phosphoenolpyruvate => ATP + Pyruvate (pyruvate kinase M2) gcr2 0.207 1 839 1 REAC:504499 re Glucose 6-phosphate is isomerized to form fructose-6-phosphate gcr2 0.207 1 839 1 REAC:500612 re alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate gcr2 0.207 1 839 1 REAC:503502 re Phosphorylation of Cdc25A at Ser-123 in response to DNA damage gcr2 0.207 1 839 1 REAC:504730 re Regulation of ornithine decarboxylase (ODC) gcr2 0.132 10 839 4 REAC:504404 re Nicotinate metabolism gcr2 0.207 1 839 1 REAC:499919 re A phospho-ribosyl group is added to quinolinate gcr2 0.113 49 839 14 REAC:504363 re Metabolism of amino acids gcr2 0.0368 7 839 4 REAC:504731 re Metabolism of polyamines gcr2 0.207 1 839 1 REAC:503965 re S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 gcr2 0.207 1 839 1 REAC:504779 re Interconversion of polyamines gcr2 0.371 2 839 1 REAC:503753 re Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine gcr2 0.207 1 839 1 REAC:503318 re ornithine => putrescine + CO2 gcr2 0.0426 2 839 2 REAC:504490 re Alanine metabolism gcr2 0.0426 2 839 2 REAC:500565 re alanine + alpha-ketoglutarate <=> pyruvate + glutamate gcr2 0.0426 2 839 2 REAC:503770 re pyruvate + glutamate <=> alanine + alpha-ketoglutarate gcr2 0.00874 3 839 3 REAC:504403 re Tryptophan catabolism gcr2 0.207 1 839 1 REAC:499776 re 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde gcr2 0.207 1 839 1 REAC:502974 re kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O gcr2 0.207 1 839 1 REAC:499782 re 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine gcr2 0.443 7 839 2 REAC:504393 re Lysine catabolism gcr2 0.371 2 839 1 REAC:499669 re 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] gcr2 0.362 6 839 2 REAC:504501 re Aspartate, asparagine, glutamate, and glutamine metabolism gcr2 0.371 2 839 1 REAC:500635 re alpha-ketoglutarate + NH4+ + NADPH + H+ => glutamate + NADP+ gcr2 0.371 2 839 1 REAC:502635 re glutamate + NAD+ => alpha-ketoglutarate + NH4+ + NADH + H+ gcr2 0.371 2 839 1 REAC:501105 re aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate gcr2 0.11 3 839 2 REAC:504479 re Phase 1 functionalization gcr2 0.207 1 839 1 REAC:504664 re FMO reactions gcr2 0.207 1 839 1 REAC:504663 re N-oxidation of nitrogen compounds gcr2 0.207 1 839 1 REAC:503279 re Nicotine N-oxidised to Nicotine-N-oxide gcr2 0.406 11 839 3 REAC:504425 re Phase 1 - Functionalization of compounds gcr2 0.207 1 839 1 REAC:504662 re FMO oxidizes nucleophiles gcr2 0.207 1 839 1 REAC:502457 re FMO2 S-oxidizes the antithyroid drug methimazole gcr2 0.207 1 839 1 REAC:502453 re FMO1 N-oxidizes the anti-cancer drug tamoxifen gcr2 0.207 1 839 1 REAC:502461 re FMO3 N-oxidizes the tertiary amine trimethylamine gcr2 0.207 1 839 1 REAC:504778 re Amine Oxidase reactions gcr2 0.207 1 839 1 REAC:504777 re Polyamines are oxidized to amines, aldehydes and H2O2 by PAOs gcr2 0.207 1 839 1 REAC:504029 re Spermine is oxidized to spermidine gcr2 0.371 2 839 1 REAC:504797 re DNA Damage Recognition in GG-NER gcr2 0.371 2 839 1 REAC:504326 re XPC:HR23B complex binds to damaged DNA site with lesion gcr2 0.371 2 839 1 REAC:504325 re XPC binds to HR23B forming a heterodimeric complex gcr2 0.371 2 839 1 REAC:501940 re D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate gcr2 0.467 12 839 3 REAC:504339 re Peroxisomal lipid metabolism gcr2 0.277 5 839 2 REAC:504392 re Alpha-oxidation of phytanate gcr2 0.207 1 839 1 REAC:499662 re 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA gcr2 0.362 6 839 2 REAC:503944 re RFC dissociates after sliding clamp formation on the C-strand of the telomere gcr2 0.207 1 839 1 REAC:502813 re Hydrolysis of PIP3 to PIP2 gcr2 0.235 29 839 8 REAC:504660 re Hemostasis gcr2 0.255 21 839 6 REAC:504766 re Further platelet releasate gcr2 0.159 7 839 3 REAC:503873 re Release of 78 kDa glucose-regulated protein gcr2 0.0426 2 839 2 REAC:503928 re Release of Tubulin alpha-4A chain gcr2 0.371 2 839 1 REAC:499491 re (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI gcr2 0.207 1 839 1 REAC:504329 re Zymosterone (cholesta-8(9), 24-dien-3-one) is reduced to zymosterol (cholesta-8(9), 24-dien-3beta-ol) gcr2 1.93e-10 152 839 62 REAC:504522 re 3' -UTR-mediated translational regulation gcr2 1.93e-10 152 839 62 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression gcr2 3.28e-08 79 839 37 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit gcr2 0.00622 76 839 25 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA gcr2 0.207 1 839 1 REAC:500051 re acetyl-CoA + carnitine => acetylcarnitine + CoASH gcr2 0.00192 259 839 70 REAC:504459 re Gene Expression gcr2 9.12e-08 200 839 69 REAC:504343 re Metabolism of proteins gcr2 0.467 12 839 3 REAC:504342 re Post-translational protein modification gcr2 0.191 4 839 2 REAC:504644 re Hypusine synthesis from eIF5A-lysine gcr2 0.11 3 839 2 REAC:502280 re EIF5A(Dhp) + O2 => EIF5A(Hyp) gcr2 8.91e-10 164 839 64 REAC:504507 re Translation gcr2 1.36e-08 139 839 55 REAC:504506 re Eukaryotic Translation Elongation gcr2 1.36e-08 139 839 55 REAC:504505 re Peptide chain elongation gcr2 7.1e-09 137 839 55 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site gcr2 7.1e-09 137 839 55 REAC:502806 re Hydrolysis of eEF1A:GTP gcr2 3.62e-09 135 839 55 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA gcr2 1.36e-08 139 839 55 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction gcr2 1.7e-10 159 839 64 REAC:504612 re Eukaryotic Translation Initiation gcr2 1.7e-10 159 839 64 REAC:504611 re Cap-dependent Translation Initiation gcr2 0.218 8 839 3 REAC:504642 re Recycling of eIF2:GDP gcr2 0.218 8 839 3 REAC:502495 re Formation of eIF2:GDP:eIF2B intermediate gcr2 0.218 8 839 3 REAC:502223 re eIF2 activation gcr2 0.00415 74 839 25 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S gcr2 0.00415 74 839 25 REAC:504671 re Translation initiation complex formation gcr2 0.00743 73 839 24 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize gcr2 0.00415 74 839 25 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation gcr2 0.00415 74 839 25 REAC:504769 re Ribosomal scanning and start codon recognition gcr2 0.00743 73 839 24 REAC:503952 re Ribosomal scanning gcr2 0.00415 74 839 25 REAC:504040 re Start codon recognition gcr2 0.00478 67 839 23 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex gcr2 0.00478 67 839 23 REAC:502531 re Formation of the 43S pre-initiation complex gcr2 0.11 3 839 2 REAC:503187 re Met-tRNAi binds to eIF2:GTP to form the ternary complex gcr2 0.11 3 839 2 REAC:501979 re De novo formation of eIF2:GTP gcr2 5.08e-09 136 839 55 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit gcr2 5.08e-09 136 839 55 REAC:504077 re The 60S subunit joins the translation initiation complex gcr2 5.08e-09 136 839 55 REAC:502286 re eIF5B:GTP is hydrolyzed and released gcr2 5.08e-09 136 839 55 REAC:504765 re Formation of a pool of free 40S subunits gcr2 5.08e-09 136 839 55 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome gcr2 0.362 6 839 2 REAC:504455 re M Phase gcr2 0.277 5 839 2 REAC:504746 re Mitotic Prometaphase gcr2 0.277 5 839 2 REAC:503596 re Phosphorylation of the SA2 Cohesion Complex gcr2 0.277 5 839 2 REAC:504747 re Mitotic Metaphase/Anaphase Transition gcr2 0.277 5 839 2 REAC:503600 re Phosphorylation of the Scc1:Cohesion Complex gcr2 0.207 1 839 1 REAC:504461 re Inosine formation gcr2 0.207 1 839 1 REAC:500332 re Adenosine + H2O => Inosine + NH3 gzf3 0.000139 13 89 4 KEGG:00740 ke Riboflavin metabolism haa1 9.26e-05 22 577 9 GO:0055114 BP oxidation reduction haa1 9.26e-05 22 577 9 GO:0022900 BP electron transport chain haa1 9.26e-05 22 577 9 GO:0022904 BP respiratory electron transport chain haa1 1.17e-05 57 577 17 GO:0016310 BP phosphorylation haa1 1.21e-05 31 577 12 GO:0006119 BP oxidative phosphorylation haa1 9.26e-05 22 577 9 GO:0042773 BP ATP synthesis coupled electron transport haa1 9.26e-05 22 577 9 GO:0042775 BP mitochondrial ATP synthesis coupled electron transport haa1 1.02e-05 26 577 11 GO:0070469 CC respiratory chain haa1 9.17e-05 335 577 53 GO:0031975 CC envelope haa1 9.17e-05 335 577 53 GO:0031967 CC organelle envelope haa1 1.28e-05 147 577 31 GO:0019866 CC organelle inner membrane haa1 3.88e-06 262 577 48 GO:0005740 CC mitochondrial envelope haa1 1.67e-06 225 577 44 GO:0031966 CC mitochondrial membrane haa1 1.47e-08 99 577 29 GO:0044455 CC mitochondrial membrane part haa1 2.27e-05 137 577 29 GO:0005743 CC mitochondrial inner membrane haa1 1.02e-05 26 577 11 GO:0005746 CC mitochondrial respiratory chain haa1 3.42e-05 39 577 13 GO:0015077 MF monovalent inorganic cation transmembrane transporter activity haa1 1.27e-05 36 577 13 GO:0015078 MF hydrogen ion transmembrane transporter activity haa1 4.45e-05 76 577 19 KEGG:00190 ke Oxidative phosphorylation haa1 7.4e-05 142 577 28 KEGG:03010 ke Ribosome hal9 0.000102 18 170 5 KEGG:00290 ke Valine, leucine and isoleucine biosynthesis hal9 0.00017 11 170 4 KEGG:00770 ke Pantothenate and CoA biosynthesis hal9 0.00117 616 170 28 KEGG:01100 ke Metabolic pathways hap2 1.91e-07 1796 1467 513 GO:0044444 CC cytoplasmic part hap2 3.74e-07 789 1467 249 GO:0005739 CC mitochondrion hap2 5.66e-06 402 1467 136 GO:0044429 CC mitochondrial part hap2 7.9e-08 346 1467 127 GO:0030529 CC ribonucleoprotein complex hap2 4.4e-06 171 1467 68 GO:0005840 CC ribosome hap2 1.19e-05 137 1467 56 GO:0003723 MF RNA binding hap2 2.1e-06 48 1467 27 GO:0008565 MF protein transporter activity hap2 9.78e-28 142 1467 96 KEGG:03010 ke Ribosome hap2 7.4e-20 200 1467 119 REAC:504343 re Metabolism of proteins hap2 1.54e-18 259 1467 140 REAC:504459 re Gene Expression hap2 1.98e-21 164 1467 106 REAC:504507 re Translation hap2 1.26e-21 139 1467 95 REAC:504506 re Eukaryotic Translation Elongation hap2 1.26e-21 139 1467 95 REAC:504505 re Peptide chain elongation hap2 1.45e-21 137 1467 94 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site hap2 1.45e-21 137 1467 94 REAC:502806 re Hydrolysis of eEF1A:GTP hap2 2.5e-22 135 1467 94 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA hap2 1.26e-21 139 1467 95 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction hap2 1.39e-21 159 1467 104 REAC:504612 re Eukaryotic Translation Initiation hap2 1.39e-21 159 1467 104 REAC:504611 re Cap-dependent Translation Initiation hap2 1.73e-06 74 1467 43 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S hap2 1.73e-06 74 1467 43 REAC:504671 re Translation initiation complex formation hap2 3.37e-06 73 1467 42 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize hap2 1.73e-06 74 1467 43 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation hap2 5.54e-06 74 1467 42 REAC:504769 re Ribosomal scanning and start codon recognition hap2 3.37e-06 73 1467 42 REAC:503952 re Ribosomal scanning hap2 5.54e-06 74 1467 42 REAC:504040 re Start codon recognition hap2 4.39e-07 67 1467 41 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex hap2 4.39e-07 67 1467 41 REAC:502531 re Formation of the 43S pre-initiation complex hap2 9.03e-23 136 1467 95 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit hap2 9.03e-23 136 1467 95 REAC:504077 re The 60S subunit joins the translation initiation complex hap2 9.03e-23 136 1467 95 REAC:502286 re eIF5B:GTP is hydrolyzed and released hap2 9.03e-23 136 1467 95 REAC:504765 re Formation of a pool of free 40S subunits hap2 9.03e-23 136 1467 95 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome hap2 1.11e-21 152 1467 101 REAC:504522 re 3' -UTR-mediated translational regulation hap2 1.11e-21 152 1467 101 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression hap2 4.58e-15 79 1467 58 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit hap2 4.37e-07 76 1467 45 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA hap4 1.98e-05 13 169 5 GO:0000920 BP cell separation during cytokinesis hap4 7.46e-06 11 169 5 GO:0007109 BP cytokinesis, completion of separation hap4 0.000218 29 169 6 KEGG:00330 ke Arginine and proline metabolism hap4 0.000476 76 169 9 KEGG:00190 ke Oxidative phosphorylation hap4 0.000172 10 169 4 KEGG:00280 ke Valine, leucine and isoleucine degradation hap4 6.43e-05 49 169 7 REAC:504363 re Metabolism of amino acids hap4 6.93e-05 11 169 4 REAC:504513 re Ornithine and proline metabolism hda1 0.000532 13 402 5 KEGG:00740 ke Riboflavin metabolism hir1 9.04e-07 152 242 21 GO:0031980 CC mitochondrial lumen hir1 9.04e-07 152 242 21 GO:0005759 CC mitochondrial matrix hir1 6.29e-06 171 242 21 GO:0005840 CC ribosome hir1 4.41e-08 75 242 16 GO:0000313 CC organellar ribosome hir1 4.41e-08 75 242 16 GO:0005761 CC mitochondrial ribosome hir1 2.93e-08 73 242 16 GO:0033279 CC ribosomal subunit hir1 7.22e-08 42 242 12 GO:0015934 CC large ribosomal subunit hir1 7.22e-08 42 242 12 GO:0000315 CC organellar large ribosomal subunit hir1 7.22e-08 42 242 12 GO:0005762 CC mitochondrial large ribosomal subunit hir1 0.00158 23 242 5 KEGG:04130 ke SNARE interactions in vesicular transport hir2 2.89e-05 34 238 8 GO:0006333 BP chromatin assembly or disassembly hir2 2.95e-08 11 238 7 GO:0000786 CC nucleosome hir2 2.95e-08 11 238 7 GO:0000788 CC nuclear nucleosome hir3 5.88e-05 2335 369 186 GO:0005737 CC cytoplasm hir3 5.92e-07 335 369 46 GO:0031975 CC envelope hir3 5.42e-09 75 369 21 GO:0000313 CC organellar ribosome hir3 5.92e-07 335 369 46 GO:0031967 CC organelle envelope hir3 3.15e-09 73 369 21 GO:0033279 CC ribosomal subunit hir3 1.88e-07 42 369 14 GO:0015934 CC large ribosomal subunit hir3 1.88e-07 42 369 14 GO:0000315 CC organellar large ribosomal subunit hir3 5.2e-09 789 369 91 GO:0005739 CC mitochondrion hir3 1.5e-16 402 369 72 GO:0044429 CC mitochondrial part hir3 9.33e-08 152 369 29 GO:0031980 CC mitochondrial lumen hir3 2.37e-09 262 369 44 GO:0005740 CC mitochondrial envelope hir3 9.33e-08 152 369 29 GO:0005759 CC mitochondrial matrix hir3 5.42e-09 75 369 21 GO:0005761 CC mitochondrial ribosome hir3 1.88e-07 42 369 14 GO:0005762 CC mitochondrial large ribosomal subunit hir3 2.8e-08 225 369 38 GO:0031966 CC mitochondrial membrane hir3 4.91e-08 99 369 23 GO:0044455 CC mitochondrial membrane part hir3 6.08e-05 137 369 22 GO:0005743 CC mitochondrial inner membrane hir3 6.65e-05 36 369 10 GO:0015078 MF hydrogen ion transmembrane transporter activity hir3 1.66e-05 91 369 18 GO:0016491 MF oxidoreductase activity hir3 9.63e-06 76 369 16 KEGG:00190 ke Oxidative phosphorylation hog1 6.44e-05 7 211 4 GO:0019773 CC proteasome core complex, alpha-subunit complex hog1 2.36e-08 89 211 17 GO:0030312 CC external encapsulating structure hog1 2.36e-08 89 211 17 GO:0005618 CC cell wall hog1 2.36e-08 89 211 17 GO:0009277 CC fungal-type cell wall hog1 2.87e-05 11 211 5 GO:0005199 MF structural constituent of cell wall hog1 0.000496 35 211 7 KEGG:03050 ke Proteasome hog1 0.00117 12 211 4 KEGG:00561 ke Glycerolipid metabolism hpa2 0.000178 13 59 3 KEGG:00740 ke Riboflavin metabolism hst1 3.11e-06 265 230 25 GO:0048856 BP anatomical structure development hst1 3.11e-06 265 230 25 GO:0009653 BP anatomical structure morphogenesis hst1 1.1e-09 114 230 20 GO:0048646 BP anatomical structure formation involved in morphogenesis hst1 5.29e-06 156 230 18 GO:0071554 BP cell wall organization or biogenesis hst1 3.07e-07 302 230 29 GO:0000003 BP reproduction hst1 9.29e-08 205 230 24 GO:0032505 BP reproduction of a single-celled organism hst1 5.77e-10 215 230 28 GO:0019953 BP sexual reproduction hst1 1.1e-09 114 230 20 GO:0043934 BP sporulation hst1 6.74e-08 117 230 18 GO:0045229 BP external encapsulating structure organization hst1 5.29e-06 156 230 18 GO:0070882 BP cellular cell wall organization or biogenesis hst1 1.19e-09 81 230 17 GO:0042546 BP cell wall biogenesis hst1 3.36e-13 51 230 17 GO:0009272 BP fungal-type cell wall biogenesis hst1 1.48e-06 143 230 18 GO:0044036 BP cell wall macromolecule metabolic process hst1 1.01e-05 283 230 25 GO:0048869 BP cellular developmental process hst1 1.78e-08 133 230 20 GO:0030154 BP cell differentiation hst1 1.1e-09 114 230 20 GO:0030435 BP sporulation resulting in formation of a cellular spore hst1 7.6e-15 42 230 17 GO:0070590 BP spore wall biogenesis hst1 2.83e-10 106 230 20 GO:0048468 BP cell development hst1 7.6e-15 42 230 17 GO:0070726 BP cell wall assembly hst1 5.54e-09 164 230 23 GO:0022414 BP reproductive process hst1 3.84e-09 161 230 23 GO:0048610 BP reproductive cellular process hst1 3.84e-09 161 230 23 GO:0022413 BP reproductive process in single-celled organism hst1 2.83e-10 106 230 20 GO:0034293 BP sexual sporulation hst1 2.83e-10 106 230 20 GO:0043935 BP sexual sporulation resulting in formation of a cellular spore hst1 2.83e-10 106 230 20 GO:0030437 BP ascospore formation hst1 7.6e-15 42 230 17 GO:0070591 BP ascospore wall biogenesis hst1 6.95e-06 159 230 18 GO:0005976 BP polysaccharide metabolic process hst1 3.12e-07 129 230 18 GO:0010383 BP cell wall polysaccharide metabolic process hst1 3.12e-07 129 230 18 GO:0006022 BP aminoglycan metabolic process hst1 3.12e-07 129 230 18 GO:0006030 BP chitin metabolic process hst1 2.45e-07 127 230 18 GO:0006037 BP cell wall chitin metabolic process hst1 6.74e-08 117 230 18 GO:0071555 BP cell wall organization hst1 6.74e-08 117 230 18 GO:0007047 BP cellular cell wall organization hst1 7.6e-15 42 230 17 GO:0042244 BP spore wall assembly hst1 7.6e-15 42 230 17 GO:0030476 BP ascospore wall assembly hst1 5.58e-08 18 230 8 GO:0042763 CC intracellular immature spore hst1 5.58e-08 18 230 8 GO:0042764 CC ascospore-type prospore hst1 5.58e-08 18 230 8 GO:0005628 CC prospore membrane hst1 0.00188 16 230 4 KEGG:00380 ke Tryptophan metabolism hst1 0.000115 29 230 5 REAC:504358 re Metabolism of vitamins and cofactors hst1 0.000115 29 230 5 REAC:504357 re Metabolism of water-soluble vitamins and cofactors hst1 3.01e-07 10 230 5 REAC:504404 re Nicotinate metabolism hst1 5.67e-06 3 230 3 REAC:504403 re Tryptophan catabolism ime1 2.7e-05 5 96 3 GO:0043562 BP cellular response to nitrogen levels ime1 2.7e-05 5 96 3 GO:0006995 BP cellular response to nitrogen starvation ime1 0.0011 29 96 4 KEGG:00250 ke Alanine, aspartate and glutamate metabolism ime1 0.000326 9 96 3 KEGG:00460 ke Cyanoamino acid metabolism ino2 3.67e-05 41 145 7 GO:0009605 BP response to external stimulus ino2 2.19e-05 38 145 7 GO:0071496 BP cellular response to external stimulus ino2 3.67e-05 41 145 7 GO:0009991 BP response to extracellular stimulus ino2 3.67e-05 41 145 7 GO:0031667 BP response to nutrient levels ino2 1.07e-06 25 145 7 GO:0042594 BP response to starvation ino2 2.19e-05 38 145 7 GO:0031668 BP cellular response to extracellular stimulus ino2 2.19e-05 38 145 7 GO:0031669 BP cellular response to nutrient levels ino2 1.39e-06 5 145 4 GO:0043562 BP cellular response to nitrogen levels ino2 1.07e-06 25 145 7 GO:0009267 BP cellular response to starvation ino2 1.39e-06 5 145 4 GO:0006995 BP cellular response to nitrogen starvation ino2 7.44e-07 9 145 5 GO:0042597 CC periplasmic space ino2 7.44e-07 9 145 5 GO:0030287 CC cell wall-bounded periplasmic space ino2 3.3e-05 9 145 4 KEGG:00460 ke Cyanoamino acid metabolism ino2 0.000479 29 145 5 KEGG:00250 ke Alanine, aspartate and glutamate metabolism ino2 0.000543 17 145 4 KEGG:00910 ke Nitrogen metabolism ixr1 8.71e-05 73 488 15 GO:0022804 MF active transmembrane transporter activity ixr1 0.00136 33 488 8 KEGG:00620 ke Pyruvate metabolism kss1 5.45e-05 89 172 10 GO:0030312 CC external encapsulating structure kss1 5.45e-05 89 172 10 GO:0005618 CC cell wall kss1 5.45e-05 89 172 10 GO:0009277 CC fungal-type cell wall leu3 2.96e-07 18 135 7 KEGG:00290 ke Valine, leucine and isoleucine biosynthesis leu3 0.00124 29 135 5 KEGG:00330 ke Arginine and proline metabolism leu3 7.16e-06 11 135 5 KEGG:00770 ke Pantothenate and CoA biosynthesis mal13 0.000334 142 62 7 KEGG:03010 ke Ribosome mal33 1.12e-06 9 513 7 GO:0042597 CC periplasmic space mal33 1.12e-06 9 513 7 GO:0030287 CC cell wall-bounded periplasmic space mal33 0.00168 17 513 6 KEGG:00910 ke Nitrogen metabolism mal33 0.000339 29 513 9 KEGG:00250 ke Alanine, aspartate and glutamate metabolism mbf1 8.72e-08 142 197 18 KEGG:03010 ke Ribosome mbf1 1.16e-05 200 197 17 REAC:504343 re Metabolism of proteins mbf1 0.000103 259 197 18 REAC:504459 re Gene Expression mbf1 4.02e-06 164 197 16 REAC:504507 re Translation mbf1 3.59e-07 139 197 16 REAC:504506 re Eukaryotic Translation Elongation mbf1 3.59e-07 139 197 16 REAC:504505 re Peptide chain elongation mbf1 2.89e-07 137 197 16 REAC:502806 re Hydrolysis of eEF1A:GTP mbf1 2.89e-07 137 197 16 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site mbf1 2.32e-07 135 197 16 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA mbf1 3.59e-07 139 197 16 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction mbf1 2.58e-06 159 197 16 REAC:504612 re Eukaryotic Translation Initiation mbf1 2.58e-06 159 197 16 REAC:504611 re Cap-dependent Translation Initiation mbf1 2.59e-07 136 197 16 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit mbf1 2.59e-07 136 197 16 REAC:504077 re The 60S subunit joins the translation initiation complex mbf1 2.59e-07 136 197 16 REAC:502286 re eIF5B:GTP is hydrolyzed and released mbf1 2.59e-07 136 197 16 REAC:504765 re Formation of a pool of free 40S subunits mbf1 2.59e-07 136 197 16 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome mbf1 1.34e-06 152 197 16 REAC:504522 re 3' -UTR-mediated translational regulation mbf1 1.34e-06 152 197 16 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression mbf1 9.63e-06 79 197 11 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit mbp1 2.33e-05 4 115 3 GO:0000731 BP DNA synthesis during DNA repair mbp1 1.95e-05 32 115 6 GO:0006312 BP mitotic recombination mbp1 9.94e-07 20 115 6 GO:0000722 BP telomere maintenance via recombination mbp1 0.000165 30 115 5 KEGG:03030 ke DNA replication mbp1 4.21e-05 20 115 5 REAC:504574 re DNA Replication Pre-Initiation mbp1 0.000284 29 115 5 REAC:504438 re G1/S Transition mbp1 4.21e-05 20 115 5 REAC:504573 re Activation of the pre-replicative complex mbp1 3.38e-06 22 115 6 REAC:504670 re DNA strand elongation mbp1 5.92e-06 14 115 5 REAC:504669 re Lagging Strand Synthesis mbp1 4e-07 9 115 5 REAC:504668 re Processive synthesis on the lagging strand mbp1 4e-07 9 115 5 REAC:504758 re Removal of the Flap Intermediate mbp1 0.000188 6 115 3 REAC:503936 re Removal of remaining Flap mbp1 1.24e-05 8 115 4 REAC:503792 re Recruitment of Dna2 endonuclease met18 0.000667 23 224 5 KEGG:04130 ke SNARE interactions in vesicular transport met28 0.0012 13 89 3 KEGG:00740 ke Riboflavin metabolism met28 0.0012 13 89 3 KEGG:00920 ke Sulfur metabolism mga1 7.33e-06 5 207 4 GO:0043562 BP cellular response to nitrogen levels mga1 7.33e-06 5 207 4 GO:0006995 BP cellular response to nitrogen starvation mga1 5.84e-06 9 207 5 GO:0042597 CC periplasmic space mga1 5.84e-06 9 207 5 GO:0030287 CC cell wall-bounded periplasmic space mga1 0.000181 9 207 4 KEGG:00460 ke Cyanoamino acid metabolism mga2 1.1e-05 70 1097 28 GO:0070925 BP organelle assembly mga2 1.04e-06 328 1097 93 GO:0022613 BP ribonucleoprotein complex biogenesis mga2 6.15e-08 306 1097 92 GO:0042254 BP ribosome biogenesis mga2 1.04e-06 60 1097 27 GO:0042255 BP ribosome assembly mga2 7.32e-08 51 1097 26 GO:0042257 BP ribosomal subunit assembly mga2 1.16e-06 92 1097 36 GO:0046483 BP heterocycle metabolic process mga2 1.79e-09 456 1097 131 GO:0044281 BP small molecule metabolic process mga2 3.89e-06 131 1097 45 GO:0044283 BP small molecule biosynthetic process mga2 5.84e-06 113 1097 40 GO:0055086 BP cellular nucleobase, nucleoside and nucleotide metabolic process mga2 1.82e-05 79 1097 30 GO:0006753 BP nucleoside phosphate metabolic process mga2 1.82e-05 79 1097 30 GO:0009117 BP nucleotide metabolic process mga2 9.37e-07 16 1097 12 GO:0009123 BP nucleoside monophosphate metabolic process mga2 3.97e-06 15 1097 11 GO:0009161 BP ribonucleoside monophosphate metabolic process mga2 1.65e-05 14 1097 10 GO:0009124 BP nucleoside monophosphate biosynthetic process mga2 6.66e-06 29 1097 16 GO:0006163 BP purine nucleotide metabolic process mga2 6.2e-06 26 1097 15 GO:0009150 BP purine ribonucleotide metabolic process mga2 2.8e-07 15 1097 12 GO:0009126 BP purine nucleoside monophosphate metabolic process mga2 1.26e-06 14 1097 11 GO:0009167 BP purine ribonucleoside monophosphate metabolic process mga2 1.53e-05 125 1097 42 GO:0006519 BP cellular amino acid and derivative metabolic process mga2 1.79e-05 98 1097 35 GO:0006520 BP cellular amino acid metabolic process mga2 6.83e-06 65 1097 27 GO:0016053 BP organic acid biosynthetic process mga2 6.83e-06 65 1097 27 GO:0046394 BP carboxylic acid biosynthetic process mga2 5.61e-06 13 1097 10 GO:0009127 BP purine nucleoside monophosphate biosynthetic process mga2 5.34e-06 23 1097 14 GO:0009310 BP amine catabolic process mga2 8.48e-07 193 1097 62 GO:0034641 BP cellular nitrogen compound metabolic process mga2 1.62e-05 40 1097 19 GO:0032040 CC small-subunit processome mga2 7.36e-58 142 1097 121 KEGG:03010 ke Ribosome mga2 7.5e-29 200 1097 126 REAC:504343 re Metabolism of proteins mga2 8.95e-19 259 1097 134 REAC:504459 re Gene Expression mga2 1.03e-40 164 1097 123 REAC:504507 re Translation mga2 1.32e-49 139 1097 118 REAC:504506 re Eukaryotic Translation Elongation mga2 1.32e-49 139 1097 118 REAC:504505 re Peptide chain elongation mga2 4.42e-51 137 1097 118 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site mga2 4.42e-51 137 1097 118 REAC:502806 re Hydrolysis of eEF1A:GTP mga2 1.25e-52 135 1097 118 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA mga2 1.32e-49 139 1097 118 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction mga2 2.42e-43 159 1097 123 REAC:504612 re Eukaryotic Translation Initiation mga2 2.42e-43 159 1097 123 REAC:504611 re Cap-dependent Translation Initiation mga2 7.38e-13 74 1097 51 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S mga2 7.38e-13 74 1097 51 REAC:504671 re Translation initiation complex formation mga2 3.1e-13 73 1097 51 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize mga2 7.38e-13 74 1097 51 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation mga2 1.17e-13 74 1097 52 REAC:504769 re Ribosomal scanning and start codon recognition mga2 3.1e-13 73 1097 51 REAC:503952 re Ribosomal scanning mga2 1.17e-13 74 1097 52 REAC:504040 re Start codon recognition mga2 8.16e-16 67 1097 51 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex mga2 8.16e-16 67 1097 51 REAC:502531 re Formation of the 43S pre-initiation complex mga2 7.6e-52 136 1097 118 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit mga2 7.6e-52 136 1097 118 REAC:504077 re The 60S subunit joins the translation initiation complex mga2 7.6e-52 136 1097 118 REAC:502286 re eIF5B:GTP is hydrolyzed and released mga2 2.76e-53 136 1097 119 REAC:504765 re Formation of a pool of free 40S subunits mga2 2.76e-53 136 1097 119 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome mga2 3.44e-46 152 1097 122 REAC:504522 re 3' -UTR-mediated translational regulation mga2 3.44e-46 152 1097 122 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression mga2 7.26e-33 79 1097 72 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit mga2 1.07e-13 76 1097 53 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA mig1 2.02e-09 32 200 11 GO:0008643 BP carbohydrate transport mig1 1.69e-08 23 200 9 GO:0015749 BP monosaccharide transport mig1 1.69e-08 23 200 9 GO:0008645 BP hexose transport mig1 1.05e-06 4 200 4 GO:0033254 CC vacuolar transporter chaperone complex mig1 1.4e-05 214 200 20 GO:0022857 MF transmembrane transporter activity mig1 3.49e-05 191 200 18 GO:0022891 MF substrate-specific transmembrane transporter activity mig1 1.41e-07 21 200 8 GO:0015144 MF carbohydrate transmembrane transporter activity mig1 5.53e-08 19 200 8 GO:0051119 MF sugar transmembrane transporter activity mig1 4.75e-07 17 200 7 GO:0015145 MF monosaccharide transmembrane transporter activity mig1 4.75e-07 17 200 7 GO:0015149 MF hexose transmembrane transporter activity mig1 2.87e-07 16 200 7 GO:0005355 MF glucose transmembrane transporter activity mig1 4.05e-06 15 200 6 GO:0015578 MF mannose transmembrane transporter activity mig1 4.05e-06 15 200 6 GO:0005353 MF fructose transmembrane transporter activity mig1 3.3e-05 3 200 3 GO:0016620 MF oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor mig1 0.000489 12 200 4 KEGG:00561 ke Glycerolipid metabolism mig1 0.00125 15 200 4 KEGG:00340 ke Histidine metabolism mig1 0.000218 10 200 4 KEGG:00280 ke Valine, leucine and isoleucine degradation mig2 8.17e-07 11 106 5 GO:0000786 CC nucleosome mig2 8.17e-07 11 106 5 GO:0000788 CC nuclear nucleosome mig2 0.000413 10 106 3 REAC:504785 re trans-Golgi Network Vesicle Budding mig2 0.000413 10 106 3 REAC:504786 re Vamp7 associated clathrin derived vesicle budding mot3 6.97e-05 35 325 9 GO:0009820 BP alkaloid metabolic process mot3 8.86e-05 36 325 9 GO:0019362 BP pyridine nucleotide metabolic process mot3 6.97e-05 35 325 9 GO:0046496 BP nicotinamide nucleotide metabolic process mot3 6.97e-05 35 325 9 GO:0006769 BP nicotinamide metabolic process mot3 3.14e-05 114 325 18 GO:0000746 BP conjugation mot3 3.14e-05 114 325 18 GO:0000747 BP conjugation with cellular fusion mot3 1.61e-07 89 325 19 GO:0030312 CC external encapsulating structure mot3 1.61e-07 89 325 19 GO:0005618 CC cell wall mot3 1.61e-07 89 325 19 GO:0009277 CC fungal-type cell wall msn1 1.49e-13 142 202 27 KEGG:03010 ke Ribosome msn1 0.00129 13 202 4 KEGG:00740 ke Riboflavin metabolism msn1 1.15e-08 200 202 29 REAC:504343 re Metabolism of proteins msn1 1.17e-08 259 202 33 REAC:504459 re Gene Expression msn1 2.93e-09 164 202 27 REAC:504507 re Translation msn1 3.45e-10 139 202 26 REAC:504506 re Eukaryotic Translation Elongation msn1 3.45e-10 139 202 26 REAC:504505 re Peptide chain elongation msn1 2.41e-10 137 202 26 REAC:502806 re Hydrolysis of eEF1A:GTP msn1 2.41e-10 137 202 26 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site msn1 1.67e-10 135 202 26 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA msn1 3.45e-10 139 202 26 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction msn1 1.36e-09 159 202 27 REAC:504612 re Eukaryotic Translation Initiation msn1 1.36e-09 159 202 27 REAC:504611 re Cap-dependent Translation Initiation msn1 0.000378 74 202 12 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S msn1 0.000378 74 202 12 REAC:504671 re Translation initiation complex formation msn1 0.00033 73 202 12 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize msn1 0.000378 74 202 12 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation msn1 0.000138 67 202 12 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex msn1 0.000138 67 202 12 REAC:502531 re Formation of the 43S pre-initiation complex msn1 0.000378 74 202 12 REAC:504769 re Ribosomal scanning and start codon recognition msn1 0.00033 73 202 12 REAC:503952 re Ribosomal scanning msn1 0.000378 74 202 12 REAC:504040 re Start codon recognition msn1 2.01e-10 136 202 26 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit msn1 2.01e-10 136 202 26 REAC:504077 re The 60S subunit joins the translation initiation complex msn1 2.01e-10 136 202 26 REAC:502286 re eIF5B:GTP is hydrolyzed and released msn1 2.01e-10 136 202 26 REAC:504765 re Formation of a pool of free 40S subunits msn1 2.01e-10 136 202 26 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome msn1 4.37e-10 152 202 27 REAC:504522 re 3' -UTR-mediated translational regulation msn1 4.37e-10 152 202 27 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression msn1 7e-06 79 202 15 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit msn1 0.000491 76 202 12 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA msn2 3.28e-05 203 266 23 GO:0034660 BP ncRNA metabolic process msn2 1.94e-05 5 266 4 GO:0043562 BP cellular response to nitrogen levels msn2 1.94e-05 5 266 4 GO:0006995 BP cellular response to nitrogen starvation msn2 7.74e-06 328 266 33 GO:0022613 BP ribonucleoprotein complex biogenesis msn2 4.77e-06 306 266 32 GO:0042254 BP ribosome biogenesis msn2 1.52e-06 208 266 26 GO:0005730 CC nucleolus msn2 8.68e-06 1169 266 81 GO:0005634 CC nucleus msn2 5.88e-07 9 266 6 GO:0042597 CC periplasmic space msn2 5.88e-07 9 266 6 GO:0030287 CC cell wall-bounded periplasmic space msn2 0.00033 9 266 4 KEGG:00460 ke Cyanoamino acid metabolism msn4 0.00052 10 108 3 KEGG:00280 ke Valine, leucine and isoleucine degradation mss11 4.73e-06 11 295 6 GO:0000786 CC nucleosome mss11 4.73e-06 11 295 6 GO:0000788 CC nuclear nucleosome mss11 1.22e-19 142 295 46 KEGG:03010 ke Ribosome mss11 1.07e-18 152 295 49 REAC:504522 re 3' -UTR-mediated translational regulation mss11 1.07e-18 152 295 49 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression mss11 3.23e-10 79 295 27 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit mss11 7.01e-07 76 295 22 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA mss11 1.02e-13 200 295 50 REAC:504343 re Metabolism of proteins mss11 8.63e-13 259 295 56 REAC:504459 re Gene Expression mss11 4.93e-17 164 295 49 REAC:504507 re Translation mss11 7.16e-17 139 295 45 REAC:504506 re Eukaryotic Translation Elongation mss11 7.16e-17 139 295 45 REAC:504505 re Peptide chain elongation mss11 3.64e-17 137 295 45 REAC:502806 re Hydrolysis of eEF1A:GTP mss11 3.64e-17 137 295 45 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site mss11 1.83e-17 135 295 45 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA mss11 7.16e-17 139 295 45 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction mss11 1.05e-17 159 295 49 REAC:504612 re Eukaryotic Translation Initiation mss11 1.05e-17 159 295 49 REAC:504611 re Cap-dependent Translation Initiation mss11 4.13e-07 74 295 22 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S mss11 4.13e-07 74 295 22 REAC:504671 re Translation initiation complex formation mss11 3.14e-07 73 295 22 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize mss11 4.13e-07 74 295 22 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation mss11 2.93e-07 67 295 21 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex mss11 2.93e-07 67 295 21 REAC:502531 re Formation of the 43S pre-initiation complex mss11 4.13e-07 74 295 22 REAC:504769 re Ribosomal scanning and start codon recognition mss11 3.14e-07 73 295 22 REAC:503952 re Ribosomal scanning mss11 4.13e-07 74 295 22 REAC:504040 re Start codon recognition mss11 2.59e-17 136 295 45 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit mss11 2.59e-17 136 295 45 REAC:504077 re The 60S subunit joins the translation initiation complex mss11 2.59e-17 136 295 45 REAC:502286 re eIF5B:GTP is hydrolyzed and released mss11 2.97e-18 136 295 46 REAC:504765 re Formation of a pool of free 40S subunits mss11 2.97e-18 136 295 46 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome mth1 5.31e-05 961 345 85 GO:0043234 CC protein complex mth1 4.88e-05 24 345 8 GO:0005484 MF SNAP receptor activity mth1 0.00169 35 345 8 KEGG:03420 ke Nucleotide excision repair mth1 6.99e-05 23 345 8 KEGG:04130 ke SNARE interactions in vesicular transport ndt80 4.15e-07 328 522 54 GO:0022613 BP ribonucleoprotein complex biogenesis ndt80 2.48e-07 306 522 52 GO:0042254 BP ribosome biogenesis ngg1 5e-05 41 69 5 GO:0009605 BP response to external stimulus ngg1 3.43e-05 38 69 5 GO:0071496 BP cellular response to external stimulus ngg1 5e-05 41 69 5 GO:0009991 BP response to extracellular stimulus ngg1 5e-05 41 69 5 GO:0031667 BP response to nutrient levels ngg1 4.01e-06 25 69 5 GO:0042594 BP response to starvation ngg1 3.43e-05 38 69 5 GO:0031668 BP cellular response to extracellular stimulus ngg1 3.43e-05 38 69 5 GO:0031669 BP cellular response to nutrient levels ngg1 4.67e-08 5 69 4 GO:0043562 BP cellular response to nitrogen levels ngg1 4.01e-06 25 69 5 GO:0009267 BP cellular response to starvation ngg1 4.67e-08 5 69 4 GO:0006995 BP cellular response to nitrogen starvation ngg1 1.07e-08 9 69 5 GO:0042597 CC periplasmic space ngg1 1.07e-08 9 69 5 GO:0030287 CC cell wall-bounded periplasmic space ngg1 5.14e-06 9 69 4 KEGG:00460 ke Cyanoamino acid metabolism ngg1 8.94e-05 17 69 4 KEGG:00910 ke Nitrogen metabolism ngg1 0.000789 29 69 4 KEGG:00250 ke Alanine, aspartate and glutamate metabolism not3 3.09e-05 6 238 4 GO:0004033 MF aldo-keto reductase activity not3 0.000117 142 238 18 KEGG:03010 ke Ribosome not3 0.000241 27 238 7 KEGG:00051 ke Fructose and mannose metabolism nut1 5.24e-05 23 266 7 GO:0009295 CC nucleoid nut1 5.24e-05 23 266 7 GO:0042645 CC mitochondrial nucleoid nut1 9.53e-05 10 266 5 KEGG:00280 ke Valine, leucine and isoleucine degradation nut1 0.00127 16 266 5 KEGG:00380 ke Tryptophan metabolism nut1 0.000197 8 266 4 REAC:504416 re Synaptic Transmission nut1 0.000197 8 266 4 REAC:504415 re Transmission across Chemical Synapses nut1 0.00028 23 266 6 REAC:504350 re Pyruvate metabolism and TCA cycle nut1 8.57e-05 19 266 6 REAC:504351 re Citric acid cycle (TCA cycle) oaf1 1.24e-05 7 323 5 GO:0019773 CC proteasome core complex, alpha-subunit complex oaf1 1.71e-08 11 323 8 GO:0000786 CC nucleosome oaf1 1.71e-08 11 323 8 GO:0000788 CC nuclear nucleosome oaf1 0.000488 35 323 7 REAC:504738 re Orc1 removal from chromatin oaf1 0.000488 35 323 7 REAC:504203 re Ubiquitinated Orc1 is degraded by the proteasome oaf1 0.000325 67 323 10 REAC:504556 re S Phase oaf1 0.000143 61 323 10 REAC:504578 re Synthesis of DNA oaf1 0.000285 66 323 10 REAC:504575 re DNA Replication oaf1 0.000488 35 323 7 REAC:504199 re Ubiquitinated Cdc6 is degraded by the proteasome oaf1 0.000488 35 323 7 REAC:504744 re G1/S DNA Damage Checkpoints oaf1 0.000488 35 323 7 REAC:504743 re p53-Independent G1/S DNA damage checkpoint oaf1 0.000488 35 323 7 REAC:504742 re p53-Independent DNA Damage Response oaf1 0.000488 35 323 7 REAC:504757 re Ubiquitin Mediated Degradation of Phosphorylated Cdc25A oaf1 0.000488 35 323 7 REAC:503737 re Proteolytic degradation of ubiquitinated-Cdc25A opi1 2.59e-05 131 250 17 GO:0044283 BP small molecule biosynthetic process opi1 5.02e-05 180 250 20 GO:0042180 BP cellular ketone metabolic process opi1 3.62e-05 176 250 20 GO:0006082 BP organic acid metabolic process opi1 3.62e-05 176 250 20 GO:0043436 BP oxoacid metabolic process opi1 3.62e-05 176 250 20 GO:0019752 BP carboxylic acid metabolic process opi1 1.97e-06 65 250 13 GO:0016053 BP organic acid biosynthetic process opi1 1.97e-06 65 250 13 GO:0046394 BP carboxylic acid biosynthetic process opi1 6.23e-05 154 250 18 GO:0006629 BP lipid metabolic process opi1 3.49e-05 72 250 12 GO:0008610 BP lipid biosynthetic process opi1 4.18e-05 6 250 4 GO:0006633 BP fatty acid biosynthetic process opi1 0.00102 23 250 6 KEGG:00564 ke Glycerophospholipid metabolism opi1 0.000592 4 250 3 KEGG:00061 ke Fatty acid biosynthesis pgd1 1.23e-05 221 443 34 GO:0005783 CC endoplasmic reticulum pgd1 2.01e-13 142 443 39 KEGG:03010 ke Ribosome pgd1 1.04e-07 200 443 40 REAC:504343 re Metabolism of proteins pgd1 9.59e-07 259 443 45 REAC:504459 re Gene Expression pgd1 6.14e-10 164 443 39 REAC:504507 re Translation pgd1 9.87e-12 139 443 38 REAC:504506 re Eukaryotic Translation Elongation pgd1 9.87e-12 139 443 38 REAC:504505 re Peptide chain elongation pgd1 5.87e-12 137 443 38 REAC:502806 re Hydrolysis of eEF1A:GTP pgd1 5.87e-12 137 443 38 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site pgd1 3.45e-12 135 443 38 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA pgd1 9.87e-12 139 443 38 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction pgd1 2.11e-10 159 443 39 REAC:504612 re Eukaryotic Translation Initiation pgd1 2.11e-10 159 443 39 REAC:504611 re Cap-dependent Translation Initiation pgd1 4.51e-12 136 443 38 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit pgd1 4.51e-12 136 443 38 REAC:504077 re The 60S subunit joins the translation initiation complex pgd1 4.51e-12 136 443 38 REAC:502286 re eIF5B:GTP is hydrolyzed and released pgd1 4.51e-12 136 443 38 REAC:504765 re Formation of a pool of free 40S subunits pgd1 4.51e-12 136 443 38 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome pgd1 2.24e-10 152 443 38 REAC:504522 re 3' -UTR-mediated translational regulation pgd1 2.24e-10 152 443 38 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression pgd1 1.51e-07 79 443 23 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit pgd1 0.000387 76 443 17 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA pho2 8.38e-05 9 638 6 GO:0042597 CC periplasmic space pho2 8.38e-05 9 638 6 GO:0030287 CC cell wall-bounded periplasmic space pho2 0.00216 616 638 88 KEGG:01100 ke Metabolic pathways pho2 0.00173 13 638 6 KEGG:00740 ke Riboflavin metabolism pho2 0.000126 9 638 6 KEGG:00460 ke Cyanoamino acid metabolism pho2 0.000602 19 638 8 KEGG:03430 ke Mismatch repair pho2 0.000572 29 638 10 REAC:504367 re Purine metabolism pho2 8.21e-05 6 638 5 REAC:504411 re De novo synthesis of IMP pho23 1.2e-06 41 123 8 GO:0009605 BP response to external stimulus pho23 8.68e-06 38 123 7 GO:0071496 BP cellular response to external stimulus pho23 1.2e-06 41 123 8 GO:0009991 BP response to extracellular stimulus pho23 1.2e-06 41 123 8 GO:0031667 BP response to nutrient levels pho23 7.81e-06 25 123 6 GO:0042594 BP response to starvation pho23 8.68e-06 38 123 7 GO:0031668 BP cellular response to extracellular stimulus pho23 8.68e-06 38 123 7 GO:0031669 BP cellular response to nutrient levels pho23 7.88e-07 5 123 4 GO:0043562 BP cellular response to nitrogen levels pho23 7.81e-06 25 123 6 GO:0009267 BP cellular response to starvation pho23 7.88e-07 5 123 4 GO:0006995 BP cellular response to nitrogen starvation pho23 3.69e-07 9 123 5 GO:0042597 CC periplasmic space pho23 3.69e-07 9 123 5 GO:0030287 CC cell wall-bounded periplasmic space pho23 0.000341 17 123 4 KEGG:00910 ke Nitrogen metabolism pho23 2.04e-05 9 123 4 KEGG:00460 ke Cyanoamino acid metabolism pho4 5.59e-41 142 567 79 KEGG:03010 ke Ribosome pho4 4.25e-24 200 567 82 REAC:504343 re Metabolism of proteins pho4 5.03e-15 259 567 82 REAC:504459 re Gene Expression pho4 4.48e-29 164 567 79 REAC:504507 re Translation pho4 1.22e-31 139 567 75 REAC:504506 re Eukaryotic Translation Elongation pho4 1.22e-31 139 567 75 REAC:504505 re Peptide chain elongation pho4 3.06e-32 137 567 75 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site pho4 3.06e-32 137 567 75 REAC:502806 re Hydrolysis of eEF1A:GTP pho4 7.41e-33 135 567 75 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA pho4 1.22e-31 139 567 75 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction pho4 2.43e-30 159 567 79 REAC:504612 re Eukaryotic Translation Initiation pho4 2.43e-30 159 567 79 REAC:504611 re Cap-dependent Translation Initiation pho4 9.45e-10 74 567 33 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pho4 9.45e-10 74 567 33 REAC:504671 re Translation initiation complex formation pho4 6.01e-10 73 567 33 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize pho4 9.45e-10 74 567 33 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation pho4 9.45e-10 74 567 33 REAC:504769 re Ribosomal scanning and start codon recognition pho4 6.01e-10 73 567 33 REAC:503952 re Ribosomal scanning pho4 9.45e-10 74 567 33 REAC:504040 re Start codon recognition pho4 1.91e-10 67 567 32 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex pho4 1.91e-10 67 567 32 REAC:502531 re Formation of the 43S pre-initiation complex pho4 1.51e-32 136 567 75 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit pho4 1.51e-32 136 567 75 REAC:504077 re The 60S subunit joins the translation initiation complex pho4 1.51e-32 136 567 75 REAC:502286 re eIF5B:GTP is hydrolyzed and released pho4 1.51e-32 136 567 75 REAC:504765 re Formation of a pool of free 40S subunits pho4 1.51e-32 136 567 75 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome pho4 3.68e-31 152 567 78 REAC:504522 re 3' -UTR-mediated translational regulation pho4 3.68e-31 152 567 78 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression pho4 8.97e-19 79 567 45 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit pho4 4.38e-10 76 567 34 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA pib2 1e-06 190 365 29 GO:0034470 BP ncRNA processing pib2 4.08e-07 203 365 31 GO:0034660 BP ncRNA metabolic process pib2 1.72e-06 124 365 22 GO:0016072 BP rRNA metabolic process pib2 4.54e-05 619 365 59 GO:0044085 BP cellular component biogenesis pib2 2.25e-08 328 365 45 GO:0022613 BP ribonucleoprotein complex biogenesis pib2 2.43e-09 306 365 45 GO:0042254 BP ribosome biogenesis pib2 7.09e-06 115 365 20 GO:0006364 BP rRNA processing pib2 3.73e-05 193 365 26 GO:0034641 BP cellular nitrogen compound metabolic process pib2 1.47e-06 427 365 49 GO:0031981 CC nuclear lumen pib2 1.87e-08 208 365 34 GO:0005730 CC nucleolus pop2 1.88e-05 64 179 10 GO:0006401 BP RNA catabolic process pop2 9.77e-06 11 179 5 GO:0000786 CC nucleosome pop2 9.77e-06 11 179 5 GO:0000788 CC nuclear nucleosome pop2 6.09e-06 801 179 46 GO:0043228 CC non-membrane-bounded organelle pop2 6.09e-06 801 179 46 GO:0043232 CC intracellular non-membrane-bounded organelle pop2 1.13e-05 1169 179 59 GO:0005634 CC nucleus pop2 8.84e-05 833 179 44 GO:0044428 CC nuclear part pop2 1.4e-05 208 179 19 GO:0005730 CC nucleolus pop2 7.7e-05 598 179 35 GO:0043233 CC organelle lumen pop2 7.7e-05 598 179 35 GO:0070013 CC intracellular organelle lumen ppr1 0.000461 13 167 4 KEGG:00740 ke Riboflavin metabolism ppr1 0.000495 23 167 5 KEGG:04130 ke SNARE interactions in vesicular transport rcs1 6.54e-07 24 730 13 GO:0015674 BP di-, tri-valent inorganic cation transport rcs1 9.1e-09 16 730 12 GO:0006826 BP iron ion transport rcs1 2.43e-05 5 730 5 GO:0034755 BP iron ion transmembrane transport rcs1 5.09e-05 71 730 21 GO:0055085 BP transmembrane transport rcs1 9.92e-06 9 730 7 GO:0015891 BP siderophore transport rcs1 9.79e-09 456 730 95 GO:0044281 BP small molecule metabolic process rcs1 6.67e-06 131 730 34 GO:0044283 BP small molecule biosynthetic process rcs1 2.48e-07 180 730 46 GO:0042180 BP cellular ketone metabolic process rcs1 3.33e-07 176 730 45 GO:0006082 BP organic acid metabolic process rcs1 3.33e-07 176 730 45 GO:0043436 BP oxoacid metabolic process rcs1 3.33e-07 176 730 45 GO:0019752 BP carboxylic acid metabolic process rcs1 1.69e-05 125 730 32 GO:0006519 BP cellular amino acid and derivative metabolic process rcs1 1.22e-05 193 730 44 GO:0034641 BP cellular nitrogen compound metabolic process rcs1 4.01e-05 113 730 29 GO:0044106 BP cellular amine metabolic process rcs1 6.12e-06 98 730 28 GO:0006520 BP cellular amino acid metabolic process rcs1 2.95e-06 65 730 22 GO:0016053 BP organic acid biosynthetic process rcs1 2.95e-06 65 730 22 GO:0046394 BP carboxylic acid biosynthetic process rcs1 4.94e-05 103 730 27 GO:0055080 BP cation homeostasis rcs1 8.86e-06 50 730 18 GO:0006457 BP protein folding rcs1 2.46e-06 8 730 7 GO:0042026 BP protein refolding rcs1 2.25e-05 35 730 14 GO:0055072 BP iron ion homeostasis rcs1 2.25e-05 35 730 14 GO:0006879 BP cellular iron ion homeostasis rcs1 2.46e-06 8 730 7 GO:0033212 BP iron assimilation rcs1 7.45e-07 2335 730 335 GO:0005737 CC cytoplasm rcs1 6.57e-05 1796 730 258 GO:0044444 CC cytoplasmic part rcs1 2.32e-05 23 730 11 GO:0009295 CC nucleoid rcs1 2.32e-05 23 730 11 GO:0042645 CC mitochondrial nucleoid rcs1 5.52e-09 91 730 32 GO:0016491 MF oxidoreductase activity rcs1 3.86e-05 28 730 12 GO:0046915 MF transition metal ion transmembrane transporter activity rcs1 2.99e-08 12 730 10 GO:0005381 MF iron ion transmembrane transporter activity rcs1 8.4e-09 616 730 133 KEGG:01100 ke Metabolic pathways rcs1 0.00216 29 730 11 KEGG:00330 ke Arginine and proline metabolism rcs1 1.54e-05 13 730 9 KEGG:00300 ke Lysine biosynthesis rcs1 0.00142 10 730 6 KEGG:00280 ke Valine, leucine and isoleucine degradation rcs1 0.000264 47 730 17 KEGG:00010 ke Glycolysis / Gluconeogenesis rcs1 0.00178 17 730 8 KEGG:00071 ke Fatty acid metabolism rcs1 0.00208 33 730 12 KEGG:00620 ke Pyruvate metabolism rcs1 0.00092 18 730 9 REAC:504376 re Purine biosynthesis rcs1 0.000603 6 730 5 REAC:504406 re Transformation of lanosterol to cholesterol rcs1 0.00294 71 730 21 REAC:504353 re Integration of energy metabolism rcs1 0.000832 48 730 17 REAC:504354 re Diabetes pathways rcs1 0.000832 48 730 17 REAC:504352 re Glucose Regulation of Insulin Secretion rcs1 0.000389 23 730 11 REAC:504350 re Pyruvate metabolism and TCA cycle rcs1 4e-05 19 730 11 REAC:504351 re Citric acid cycle (TCA cycle) rdr1 0.00036 23 229 6 KEGG:04130 ke SNARE interactions in vesicular transport rdr1 0.00018 66 229 8 REAC:504575 re DNA Replication rdr1 0.000201 67 229 8 REAC:504556 re S Phase rdr1 1e-04 61 229 8 REAC:504578 re Synthesis of DNA rds1 0.000169 40 218 8 KEGG:00500 ke Starch and sucrose metabolism rfx1 5.67e-05 41 203 8 GO:0009605 BP response to external stimulus rfx1 5.67e-05 41 203 8 GO:0009991 BP response to extracellular stimulus rfx1 5.67e-05 41 203 8 GO:0031667 BP response to nutrient levels rfx1 6.36e-06 5 203 4 GO:0043562 BP cellular response to nitrogen levels rfx1 1.36e-05 25 203 7 GO:0042594 BP response to starvation rfx1 1.36e-05 25 203 7 GO:0009267 BP cellular response to starvation rfx1 6.36e-06 5 203 4 GO:0006995 BP cellular response to nitrogen starvation rfx1 0.000134 9 203 4 KEGG:00460 ke Cyanoamino acid metabolism rfx1 0.000173 17 203 5 KEGG:00910 ke Nitrogen metabolism rfx1 0.00034 6 203 3 REAC:504469 re Reduction of nuclear ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates by ribonucleotide reductase and thioredoxin rfx1 0.00034 6 203 3 REAC:504467 re Reduction of cytosolic ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates by ribonucleotide reductase and thioredoxin rfx1 0.00034 6 203 3 REAC:504464 re Reduction of cytosolic ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates by ribonucleotide reductase and glutaredoxin rgm1 2.67e-05 22 257 7 GO:0055114 BP oxidation reduction rgm1 3.68e-05 129 257 17 GO:0006091 BP generation of precursor metabolites and energy rgm1 2.67e-05 22 257 7 GO:0022900 BP electron transport chain rgm1 2.67e-05 22 257 7 GO:0022904 BP respiratory electron transport chain rgm1 4.24e-06 31 257 9 GO:0006119 BP oxidative phosphorylation rgm1 2.67e-05 22 257 7 GO:0042773 BP ATP synthesis coupled electron transport rgm1 2.67e-05 22 257 7 GO:0042775 BP mitochondrial ATP synthesis coupled electron transport rgm1 8.86e-05 26 257 7 GO:0070469 CC respiratory chain rgm1 4.18e-05 335 257 31 GO:0031975 CC envelope rgm1 4.18e-05 335 257 31 GO:0031967 CC organelle envelope rgm1 1.68e-05 147 257 19 GO:0019866 CC organelle inner membrane rgm1 2.07e-05 262 257 27 GO:0005740 CC mitochondrial envelope rgm1 1.17e-05 225 257 25 GO:0031966 CC mitochondrial membrane rgm1 4.48e-06 99 257 16 GO:0044455 CC mitochondrial membrane part rgm1 2.25e-05 137 257 18 GO:0005743 CC mitochondrial inner membrane rgm1 8.86e-05 26 257 7 GO:0005746 CC mitochondrial respiratory chain rgm1 1.82e-05 76 257 13 KEGG:00190 ke Oxidative phosphorylation rgm1 4.38e-05 40 257 9 KEGG:00500 ke Starch and sucrose metabolism rgm1 0.000365 48 257 8 REAC:504354 re Diabetes pathways rgm1 0.000365 48 257 8 REAC:504352 re Glucose Regulation of Insulin Secretion rgm1 0.00014 8 257 4 REAC:504500 re Glycogen synthesis ric1 4.44e-05 92 650 23 GO:0046483 BP heterocycle metabolic process ric1 1.17e-12 456 650 96 GO:0044281 BP small molecule metabolic process ric1 7.77e-08 131 650 35 GO:0044283 BP small molecule biosynthetic process ric1 2.79e-10 180 650 48 GO:0042180 BP cellular ketone metabolic process ric1 7.86e-07 113 650 30 GO:0055086 BP cellular nucleobase, nucleoside and nucleotide metabolic process ric1 2.83e-06 79 650 23 GO:0006753 BP nucleoside phosphate metabolic process ric1 2.83e-06 79 650 23 GO:0009117 BP nucleotide metabolic process ric1 8.46e-05 29 650 11 GO:0009259 BP ribonucleotide metabolic process ric1 8.46e-05 29 650 11 GO:0006163 BP purine nucleotide metabolic process ric1 2.53e-05 26 650 11 GO:0009150 BP purine ribonucleotide metabolic process ric1 3.52e-06 69 650 21 GO:0044282 BP small molecule catabolic process ric1 4.12e-10 176 650 47 GO:0006082 BP organic acid metabolic process ric1 4.12e-10 176 650 47 GO:0043436 BP oxoacid metabolic process ric1 4.12e-10 176 650 47 GO:0019752 BP carboxylic acid metabolic process ric1 5.79e-05 28 650 11 GO:0016054 BP organic acid catabolic process ric1 5.79e-05 28 650 11 GO:0046395 BP carboxylic acid catabolic process ric1 2.11e-08 125 650 35 GO:0006519 BP cellular amino acid and derivative metabolic process ric1 1.15e-09 193 650 49 GO:0034641 BP cellular nitrogen compound metabolic process ric1 4.35e-06 247 650 49 GO:0009308 BP amine metabolic process ric1 6.64e-07 23 650 12 GO:0009310 BP amine catabolic process ric1 2.31e-07 113 650 31 GO:0044106 BP cellular amine metabolic process ric1 2.4e-08 98 650 30 GO:0006520 BP cellular amino acid metabolic process ric1 7.89e-05 20 650 9 GO:0009064 BP glutamine family amino acid metabolic process ric1 6.61e-05 6 650 5 GO:0009081 BP branched chain family amino acid metabolic process ric1 9.7e-06 20 650 10 GO:0009063 BP cellular amino acid catabolic process ric1 7.92e-05 9 650 6 GO:0009065 BP glutamine family amino acid catabolic process ric1 1.96e-05 65 650 19 GO:0016053 BP organic acid biosynthetic process ric1 1.96e-05 65 650 19 GO:0046394 BP carboxylic acid biosynthetic process ric1 6.14e-05 70 650 19 GO:0070925 BP organelle assembly ric1 2.19e-05 60 650 18 GO:0042255 BP ribosome assembly ric1 3.4e-05 51 650 16 GO:0042257 BP ribosomal subunit assembly ric1 1.05e-05 13 650 8 GO:0006448 BP regulation of translational elongation ric1 1.63e-06 11 650 8 GO:0006450 BP regulation of translational fidelity ric1 7.92e-05 16 650 8 GO:0016614 MF oxidoreductase activity, acting on CH-OH group of donors ric1 2.25e-42 142 650 93 KEGG:03010 ke Ribosome ric1 0.00191 29 650 12 KEGG:00330 ke Arginine and proline metabolism ric1 0.000258 18 650 10 KEGG:00290 ke Valine, leucine and isoleucine biosynthesis ric1 0.00191 29 650 12 KEGG:00250 ke Alanine, aspartate and glutamate metabolism ric1 3.09e-05 8 650 7 KEGG:00980 ke Metabolism of xenobiotics by cytochrome P450 ric1 0.000487 29 650 13 KEGG:00270 ke Cysteine and methionine metabolism ric1 8.95e-06 47 650 21 KEGG:00010 ke Glycolysis / Gluconeogenesis ric1 3.76e-22 200 650 96 REAC:504343 re Metabolism of proteins ric1 1.12e-16 259 650 104 REAC:504459 re Gene Expression ric1 8.63e-30 164 650 94 REAC:504507 re Translation ric1 1.44e-36 139 650 92 REAC:504506 re Eukaryotic Translation Elongation ric1 1.44e-36 139 650 92 REAC:504505 re Peptide chain elongation ric1 2.15e-37 137 650 92 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site ric1 2.15e-37 137 650 92 REAC:502806 re Hydrolysis of eEF1A:GTP ric1 3e-38 135 650 92 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA ric1 1.44e-36 139 650 92 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction ric1 2.26e-31 159 650 94 REAC:504612 re Eukaryotic Translation Initiation ric1 2.26e-31 159 650 94 REAC:504611 re Cap-dependent Translation Initiation ric1 3.01e-07 74 650 35 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S ric1 3.01e-07 74 650 35 REAC:504671 re Translation initiation complex formation ric1 1.95e-07 73 650 35 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize ric1 3.01e-07 74 650 35 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation ric1 7.7e-08 74 650 36 REAC:504769 re Ribosomal scanning and start codon recognition ric1 1.95e-07 73 650 35 REAC:503952 re Ribosomal scanning ric1 7.7e-08 74 650 36 REAC:504040 re Start codon recognition ric1 4.9e-08 67 650 34 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex ric1 4.9e-08 67 650 34 REAC:502531 re Formation of the 43S pre-initiation complex ric1 8.09e-38 136 650 92 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit ric1 8.09e-38 136 650 92 REAC:504077 re The 60S subunit joins the translation initiation complex ric1 8.09e-38 136 650 92 REAC:502286 re eIF5B:GTP is hydrolyzed and released ric1 8.09e-38 136 650 92 REAC:504765 re Formation of a pool of free 40S subunits ric1 8.09e-38 136 650 92 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome ric1 9.82e-33 152 650 93 REAC:504522 re 3' -UTR-mediated translational regulation ric1 9.82e-33 152 650 93 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression ric1 2.16e-26 79 650 59 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit ric1 4.74e-08 76 650 37 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA rif1 1.76e-05 625 356 60 GO:0010467 BP gene expression rif1 8.49e-05 27 356 8 GO:0033750 BP ribosome localization rif1 7.15e-11 619 356 74 GO:0044085 BP cellular component biogenesis rif1 2.87e-05 70 356 14 GO:0070925 BP organelle assembly rif1 3.68e-19 328 356 63 GO:0022613 BP ribonucleoprotein complex biogenesis rif1 4.2e-20 306 356 62 GO:0042254 BP ribosome biogenesis rif1 2.26e-05 60 356 13 GO:0042255 BP ribosome assembly rif1 9.48e-07 61 356 15 GO:0042273 BP ribosomal large subunit biogenesis rif1 8.49e-05 27 356 8 GO:0033753 BP establishment of ribosome localization rif1 3.67e-05 1101 356 91 GO:0006139 BP cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolic process rif1 1.68e-07 558 356 61 GO:0016070 BP cellular RNA metabolic process rif1 2.33e-11 203 356 38 GO:0034660 BP ncRNA metabolic process rif1 1.64e-08 124 356 25 GO:0016072 BP rRNA metabolic process rif1 6.54e-07 337 356 42 GO:0006396 BP RNA processing rif1 1.03e-09 190 356 34 GO:0034470 BP ncRNA processing rif1 3.28e-07 115 356 22 GO:0006364 BP rRNA processing rif1 1.41e-05 66 356 14 GO:0009451 BP RNA modification rif1 8.49e-05 27 356 8 GO:0000054 BP ribosomal subunit export from nucleus rif1 8.41e-05 50 356 11 GO:0006400 BP tRNA modification rif1 8.6e-07 53 356 14 GO:0030684 CC preribosome rif1 1.36e-08 8 356 7 GO:0030687 CC preribosome, large subunit precursor rif1 2.69e-06 631 356 63 GO:0031974 CC membrane-enclosed lumen rif1 8.91e-07 598 356 62 GO:0043233 CC organelle lumen rif1 8.91e-07 598 356 62 GO:0070013 CC intracellular organelle lumen rif1 2.27e-06 1169 356 100 GO:0005634 CC nucleus rif1 1.24e-05 833 356 75 GO:0044428 CC nuclear part rif1 2.46e-09 427 356 55 GO:0031981 CC nuclear lumen rif1 5.02e-11 208 356 38 GO:0005730 CC nucleolus rim101 1.33e-05 117 491 24 GO:0048878 BP chemical homeostasis rim101 1.33e-05 117 491 24 GO:0050801 BP ion homeostasis rim101 1.56e-05 103 491 22 GO:0055080 BP cation homeostasis rim101 2.59e-09 60 491 21 GO:0055066 BP di-, tri-valent inorganic cation homeostasis rim101 2.22e-09 35 491 16 GO:0055072 BP iron ion homeostasis rim101 2.6e-06 889 491 107 GO:0051179 BP localization rim101 3.45e-06 841 491 102 GO:0051234 BP establishment of localization rim101 2.83e-06 827 491 101 GO:0006810 BP transport rim101 1.45e-07 86 491 23 GO:0006811 BP ion transport rim101 7.71e-08 71 491 21 GO:0006812 BP cation transport rim101 7.58e-07 24 491 11 GO:0015674 BP di-, tri-valent inorganic cation transport rim101 1.75e-10 53 491 21 GO:0030001 BP metal ion transport rim101 7.89e-12 42 491 20 GO:0000041 BP transition metal ion transport rim101 1.15e-05 12 491 7 GO:0006825 BP copper ion transport rim101 5.22e-08 16 491 10 GO:0006826 BP iron ion transport rim101 2.61e-07 6 491 6 GO:0015688 BP iron chelate transport rim101 1.37e-08 9 491 8 GO:0015891 BP siderophore transport rim101 2.46e-06 114 491 25 GO:0019725 BP cellular homeostasis rim101 7.09e-06 113 491 24 GO:0055082 BP cellular chemical homeostasis rim101 7.09e-06 113 491 24 GO:0006873 BP cellular ion homeostasis rim101 7.96e-06 99 491 22 GO:0030003 BP cellular cation homeostasis rim101 2.59e-09 60 491 21 GO:0030005 BP cellular di-, tri-valent inorganic cation homeostasis rim101 2.22e-09 35 491 16 GO:0006879 BP cellular iron ion homeostasis rim101 1.64e-09 8 491 8 GO:0033212 BP iron assimilation rim101 2.61e-07 6 491 6 GO:0033214 BP iron assimilation by chelation and transport rim101 2.61e-07 6 491 6 GO:0015892 BP siderophore-iron transport rim101 1.79e-06 71 491 19 GO:0055085 BP transmembrane transport rim101 3.79e-05 23 491 9 GO:0034220 BP ion transmembrane transport rim101 4.69e-06 89 491 21 GO:0030312 CC external encapsulating structure rim101 4.69e-06 89 491 21 GO:0005618 CC cell wall rim101 4.69e-06 89 491 21 GO:0009277 CC fungal-type cell wall rim101 2.46e-06 268 491 44 GO:0005215 MF transporter activity rim101 1.83e-05 244 491 39 GO:0022892 MF substrate-specific transporter activity rim101 4.12e-05 4 491 4 GO:0042927 MF siderophore transporter activity rim101 7.3e-05 214 491 34 GO:0022857 MF transmembrane transporter activity rim101 6.06e-09 37 491 16 GO:0046873 MF metal ion transmembrane transporter activity rim101 4.16e-10 28 491 15 GO:0046915 MF transition metal ion transmembrane transporter activity rim101 7.43e-10 33 491 16 GO:0015082 MF di-, tri-valent inorganic cation transmembrane transporter activity rim101 2.28e-08 12 491 9 GO:0005381 MF iron ion transmembrane transporter activity rim101 4.12e-05 4 491 4 GO:0015343 MF siderophore-iron transmembrane transporter activity rim101 2.73e-05 99 491 21 GO:0015075 MF ion transmembrane transporter activity rim101 1.6e-05 17 491 8 KEGG:00910 ke Nitrogen metabolism rim101 4.86e-06 29 491 11 KEGG:00250 ke Alanine, aspartate and glutamate metabolism rim101 0.00112 616 491 65 KEGG:01100 ke Metabolic pathways rlf2 0.000102 40 837 15 GO:0006733 BP oxidoreduction coenzyme metabolic process rlf2 0.000102 40 837 15 GO:0019748 BP secondary metabolic process rlf2 1.57e-05 35 837 15 GO:0009820 BP alkaloid metabolic process rlf2 2.37e-05 36 837 15 GO:0019362 BP pyridine nucleotide metabolic process rlf2 1.57e-05 35 837 15 GO:0046496 BP nicotinamide nucleotide metabolic process rlf2 1.57e-05 35 837 15 GO:0006769 BP nicotinamide metabolic process rlf2 3.86e-05 193 837 46 GO:0034641 BP cellular nitrogen compound metabolic process rlf2 1.1e-05 11 837 8 GO:0000786 CC nucleosome rlf2 1.1e-05 11 837 8 GO:0000788 CC nuclear nucleosome rlf2 0.00014 47 837 19 KEGG:00010 ke Glycolysis / Gluconeogenesis rlf2 4.99e-22 142 837 72 KEGG:03010 ke Ribosome rlf2 0.221 1 837 1 REAC:502642 re glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate rlf2 0.0768 8 837 4 REAC:504416 re Synaptic Transmission rlf2 0.0768 8 837 4 REAC:504415 re Transmission across Chemical Synapses rlf2 0.214 4 837 2 REAC:504414 re Neurotransmitter Clearance In The Synaptic Cleft rlf2 0.214 4 837 2 REAC:504413 re Serotonin clearance from the synaptic cleft rlf2 0.214 4 837 2 REAC:504412 re Metabolism of serotonin rlf2 0.214 4 837 2 REAC:499890 re 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid rlf2 0.21 11 837 4 REAC:504476 re Formation of tubulin folding intermediates by CCT/TriC rlf2 0.21 11 837 4 REAC:500450 re ADP is exchanged for ATP in the (ADP:CCT/TriC):tubulin complex rlf2 0.21 11 837 4 REAC:502800 re Hydrolysis of ATP and release of tubulin folding intermediate from CCT/TriC rlf2 0.125 3 837 2 REAC:504403 re Tryptophan catabolism rlf2 0.16 10 837 4 REAC:504404 re Nicotinate metabolism rlf2 0.221 1 837 1 REAC:499776 re 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde rlf2 0.221 1 837 1 REAC:502974 re kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O rlf2 0.221 1 837 1 REAC:504181 re tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate rlf2 0.214 4 837 2 REAC:504737 re Innate Immunity Signaling rlf2 0.214 4 837 2 REAC:504736 re Toll Receptor Cascades rlf2 0.214 4 837 2 REAC:504735 re Toll Like Receptor 3 (TLR3) Cascade rlf2 0.214 4 837 2 REAC:504734 re TRAF6 Mediated Induction of the antiviral cytokine IFN-alpha/beta cascade rlf2 0.214 4 837 2 REAC:503462 re Phosphorylated MAPK1 phosphorylates ATF-2 rlf2 0.186 7 837 3 REAC:504527 re Homologous Recombination Repair rlf2 0.186 7 837 3 REAC:504526 re Homologous recombination repair of replication-independent double-strand breaks rlf2 0.125 3 837 2 REAC:504639 re ATM mediated response to DNA double-strand break rlf2 0.125 3 837 2 REAC:504745 re ATM mediated phosphorylation of repair proteins rlf2 0.125 3 837 2 REAC:503550 re Phosphorylation of histone H2AX at Serine-139 by ATM at the site of DSB rlf2 0.0724 11 837 5 REAC:504510 re Golgi to ER Retrograde Transport rlf2 0.0724 11 837 5 REAC:504509 re COPI Mediated Transport rlf2 0.186 7 837 3 REAC:503993 re Sculpting and pinching-off of Golgi vessicle rlf2 0.029 9 837 5 REAC:501739 re Coatomer:Arf1-GTP:GAP lattice formation on golgi membrane rlf2 0.0768 8 837 4 REAC:501734 re Coat Complex Formation rlf2 0.214 4 837 2 REAC:501035 re Arf1 Activation by GBF1 rlf2 0.029 9 837 5 REAC:502575 re GAP Recruitment to the Coatomer:Arf1-GTP Complex rlf2 0.029 9 837 5 REAC:502796 re Hydrolysis of Arf1-GTP to Arf1-GDP rlf2 0.029 9 837 5 REAC:502113 re Diffusion of inactive Arf1-GDP from membrane rlf2 0.186 7 837 3 REAC:502743 re Golgi vesicle lattice disassociation rlf2 1.43e-17 152 837 76 REAC:504522 re 3' -UTR-mediated translational regulation rlf2 1.43e-17 152 837 76 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression rlf2 6.38e-08 79 837 38 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit rlf2 7.93e-10 76 837 40 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA rlf2 0.172 45 837 13 REAC:504348 re Glucose metabolism rlf2 0.0352 22 837 9 REAC:504355 re Gluconeogenesis rlf2 0.221 1 837 1 REAC:501928 re D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate rlf2 0.0749 5 837 3 REAC:503441 re Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate rlf2 0.221 1 837 1 REAC:501332 re ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate rlf2 0.221 1 837 1 REAC:499677 re 2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate rlf2 0.221 1 837 1 REAC:501955 re D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate rlf2 0.221 1 837 1 REAC:503331 re oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [mitochondrial matrix] rlf2 0.221 1 837 1 REAC:501094 re aspartate + alpha-ketoglutarate <=> oxaloacetate + glutamate [cytosol] rlf2 0.00487 17 837 9 REAC:504394 re Glycolysis rlf2 0.221 1 837 1 REAC:499788 re 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate rlf2 0.0749 5 837 3 REAC:499691 re 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O rlf2 0.221 1 837 1 REAC:504620 re Dihydroxyacetone phosphate is isomerized to form glyceraldehyde-3-phosphate rlf2 0.221 1 837 1 REAC:502123 re dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate rlf2 0.221 1 837 1 REAC:504474 re 1,3-bisphosphoglycerate and ADP react to form 3-phosphoglycerate and ATP rlf2 0.221 1 837 1 REAC:500427 re ADP + 3-Phospho-D-glyceroyl phosphate <=> ATP + 3-Phospho-D-glycerate rlf2 0.221 1 837 1 REAC:504499 re Glucose 6-phosphate is isomerized to form fructose-6-phosphate rlf2 0.221 1 837 1 REAC:500612 re alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate rlf2 0.221 1 837 1 REAC:503086 re lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O rlf2 0.221 1 837 1 REAC:503330 re oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [cytosolic] rlf2 0.221 1 837 1 REAC:503652 re propionyl-CoA + carnitine => propionylcarnitine + CoASH rlf2 0.221 1 837 1 REAC:503651 re proline => L-1-pyrroline-5-carboxylate rlf2 0.0487 2 837 2 REAC:503928 re Release of Tubulin alpha-4A chain rlf2 0.221 1 837 1 REAC:500330 re Adenine + PRPP => AMP + PPi rlf2 0.221 1 837 1 REAC:500418 re adenylosuccinate => adenosine 5'-monophosphate + fumarate rlf2 0.214 4 837 2 REAC:504784 re Vamp2 associated Clathrin derived vesicle budding rlf2 0.214 4 837 2 REAC:504787 re Vamp8 associated clathrin derived vesicle budding rlf2 0.214 4 837 2 REAC:504119 re trans-Golgi Network Coat Activation rlf2 0.221 1 837 1 REAC:504791 re Recycling of bile acids and salts rlf2 0.221 1 837 1 REAC:504158 re Transport (efflux) of bile salts by ABCB11 (bile salt export pump) rlf2 0.221 1 837 1 REAC:503161 re mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol rlf2 0.125 3 837 2 REAC:503327 re orotate + 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) <=> orotidine 5'-monophosphate (OMP) + pyrophosphate rlf2 0.214 4 837 2 REAC:504593 re Conversion of Fatty Acyl-CoA to Phosphatidic Acid rlf2 0.125 3 837 2 REAC:504592 re Synthesis of lysophosphatidic acid from glycerol-3-phosphate rlf2 0.125 3 837 2 REAC:504591 re Formation of Cytosolic Glycerol-3-phosphate rlf2 0.0487 2 837 2 REAC:501793 re Conversion of Dihydroxyacetone Phosphate to Glycerol -3- phosphate rlf2 0.125 3 837 2 REAC:503329 re orotidine 5'-monophosphate => uridine 5'-monophosphate + CO2 rlf2 0.221 1 837 1 REAC:499662 re 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA rlf2 0.0594 17 837 7 REAC:504426 re Biological oxidations rlf2 0.21 11 837 4 REAC:504425 re Phase 1 - Functionalization of compounds rlf2 0.186 7 837 3 REAC:504424 re Ethanol catabolism rlf2 0.214 4 837 2 REAC:504423 re Aldehyde Dehydrogenase rlf2 0.214 4 837 2 REAC:504422 re Acetaldehyde is oxidized by NAD+ to form acetate, NADH, and H+ rlf2 0.214 4 837 2 REAC:500035 re Acetaldehyde + NAD+ <=> Acetate + NADH + H+ [mitochondrial] rlf2 0.214 4 837 2 REAC:500034 re Acetaldehyde + NAD+ <=> Acetate + NADH + H+ [cytosolic] rlf2 0.126 6 837 3 REAC:504675 re Phase II conjugation rlf2 0.0107 3 837 3 REAC:504775 re Methylation rlf2 0.221 1 837 1 REAC:503971 re S-adenoylhomocysteine is hydrolyzed rlf2 0.186 7 837 3 REAC:504731 re Metabolism of polyamines rlf2 0.221 1 837 1 REAC:503965 re S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 rlf2 0.0487 2 837 2 REAC:503992 re SAM is sythesized from methionine's reaction with ATP rlf2 0.186 7 837 3 REAC:504504 re Post-chaperonin tubulin folding pathway rlf2 0.125 3 837 2 REAC:500648 re alpha-tubulin:GTP + Cofactor E -> alpha-tubulin:GTP:Cofactor E rlf2 0.214 4 837 2 REAC:500649 re alpha-tubulin:GTP:Cofactor B +Cofactor E -> alpha-tubulin:GTP: Cofactor E +Cofactor B rlf2 0.0749 5 837 3 REAC:501426 re Beta-tubulin:GTP:Cofactor D+alpha-tubulin:GTP:Cofactor E-> Beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E rlf2 0.125 3 837 2 REAC:500644 re alpha-tubulin:GTP + Cofactor B -> alpha-tubulin:GTP: Cofactor B rlf2 0.221 1 837 1 REAC:503981 re saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ rlf2 0.214 4 837 2 REAC:504644 re Hypusine synthesis from eIF5A-lysine rlf2 0.125 3 837 2 REAC:502260 re EIF5A + spermidine <=> EIF5A(Dhp) + 1,3-diaminopropane rlf2 0.125 3 837 2 REAC:502280 re EIF5A(Dhp) + O2 => EIF5A(Hyp) rlf2 0.126 6 837 3 REAC:504411 re De novo synthesis of IMP rlf2 0.221 1 837 1 REAC:499851 re 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide (SAICAR) <=> 5'-phosphoribosyl-5-aminoimidazole-4-carboxamide (AICAR) + fumarate rlf2 0.221 1 837 1 REAC:499857 re 5'-phosphoribosylformylglycinamide (FGAR) + L-glutamine + ATP + H2O => 5'-phosphoribosylformylglycinamidine (FGAM) + L-glutamate + adenosine 5'-diphosphate + orthophosphate rlf2 0.125 3 837 2 REAC:504680 re Glyoxylate metabolism rlf2 0.221 1 837 1 REAC:502726 re glycolate + O2 => glyoxylate + H2O2 rlf2 0.221 1 837 1 REAC:502738 re glyoxylate + O2 => oxalate + H2O2 rlf2 0.221 1 837 1 REAC:502732 re glyoxylate + alanine => glycine + pyruvate rlf2 0.186 7 837 3 REAC:504740 re S6K1 signalling rlf2 0.214 4 837 2 REAC:503582 re Phosphorylation of Ribosomal protein S6 by activated S6K1 rlf2 0.221 1 837 1 REAC:504462 re Reversible phosphorylation of mitochondrial nucleoside monophosphates by adenylate kinase 2 rlf2 0.221 1 837 1 REAC:500408 re adenosine 5'-monophosphate (AMP) + ATP <=> adenosine 5'-diphosphate (ADP) + ADP rlf2 0.221 1 837 1 REAC:500337 re adenosine 5'-diphosphate (ADP) + ADP <=> adenosine 5'-monophosphate (AMP) + ATP rlf2 0.221 1 837 1 REAC:502650 re Glutamate conversion to glutamine rlf2 0.221 1 837 1 REAC:501085 re asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate rlf2 0.221 1 837 1 REAC:504699 re Conversion of cytosolic inosine 5'-monophosphate, L-aspartate, and GTP to adenylosuccinate, guanosine 5'-diphosphate, and orthophosphate rlf2 0.221 1 837 1 REAC:502896 re inosine 5'-monophosphate + L-aspartate + GTP => adenylosuccinate + guanosine 5'-diphosphate + orthophosphate rlf2 7.82e-15 200 837 86 REAC:504343 re Metabolism of proteins rlf2 5.41e-08 259 837 88 REAC:504459 re Gene Expression rlf2 2.15e-16 164 837 78 REAC:504507 re Translation rlf2 3.37e-16 139 837 70 REAC:504506 re Eukaryotic Translation Elongation rlf2 3.37e-16 139 837 70 REAC:504505 re Peptide chain elongation rlf2 1.17e-16 137 837 70 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site rlf2 1.17e-16 137 837 70 REAC:502806 re Hydrolysis of eEF1A:GTP rlf2 2.14e-16 135 837 69 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA rlf2 3.37e-16 139 837 70 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction rlf2 9.52e-17 159 837 77 REAC:504612 re Eukaryotic Translation Initiation rlf2 9.52e-17 159 837 77 REAC:504611 re Cap-dependent Translation Initiation rlf2 1.29e-09 74 837 39 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S rlf2 1.29e-09 74 837 39 REAC:504671 re Translation initiation complex formation rlf2 3.56e-09 73 837 38 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize rlf2 1.29e-09 74 837 39 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation rlf2 1.29e-09 74 837 39 REAC:504769 re Ribosomal scanning and start codon recognition rlf2 3.56e-09 73 837 38 REAC:503952 re Ribosomal scanning rlf2 1.29e-09 74 837 39 REAC:504040 re Start codon recognition rlf2 1.5e-08 67 837 35 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex rlf2 1.5e-08 67 837 35 REAC:502531 re Formation of the 43S pre-initiation complex rlf2 3.63e-16 136 837 69 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit rlf2 3.63e-16 136 837 69 REAC:504077 re The 60S subunit joins the translation initiation complex rlf2 3.63e-16 136 837 69 REAC:502286 re eIF5B:GTP is hydrolyzed and released rlf2 3.63e-16 136 837 69 REAC:504765 re Formation of a pool of free 40S subunits rlf2 3.63e-16 136 837 69 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome rlf2 0.221 1 837 1 REAC:501098 re aspartate + alpha-ketoglutarate <=> oxaloacetate + glutamate [mitochondrial] rlf2 0.221 1 837 1 REAC:504705 re Endogenous sterols rlf2 0.221 1 837 1 REAC:502992 re Lanosterol is oxidatively demethylated to 4,4-dimethylcholesta-8(9), 14,24-trien-3beta-ol rlf2 0.221 1 837 1 REAC:500051 re acetyl-CoA + carnitine => acetylcarnitine + CoASH rlf2 0.221 1 837 1 REAC:502979 re L-1-pyrroline-5-carboxylate + NADPH + H+ => proline + NADP+ rlf2 0.125 3 837 2 REAC:502261 re EIF5A(Dhp) + 1,3-diaminopropane <=> EIF5A + spermidine rlm1 2.66e-05 41 58 5 GO:0009605 BP response to external stimulus rlm1 1.82e-05 38 58 5 GO:0071496 BP cellular response to external stimulus rlm1 2.66e-05 41 58 5 GO:0009991 BP response to extracellular stimulus rlm1 2.66e-05 41 58 5 GO:0031667 BP response to nutrient levels rlm1 2.1e-06 25 58 5 GO:0042594 BP response to starvation rlm1 1.82e-05 38 58 5 GO:0031668 BP cellular response to extracellular stimulus rlm1 1.82e-05 38 58 5 GO:0031669 BP cellular response to nutrient levels rlm1 2.75e-08 5 58 4 GO:0043562 BP cellular response to nitrogen levels rlm1 2.1e-06 25 58 5 GO:0009267 BP cellular response to starvation rlm1 2.75e-08 5 58 4 GO:0006995 BP cellular response to nitrogen starvation rlm1 6.6e-05 117 58 7 GO:0045229 BP external encapsulating structure organization rlm1 0.000123 129 58 7 GO:0010383 BP cell wall polysaccharide metabolic process rlm1 0.000123 129 58 7 GO:0006022 BP aminoglycan metabolic process rlm1 0.000123 129 58 7 GO:0006030 BP chitin metabolic process rlm1 0.000111 127 58 7 GO:0006037 BP cell wall chitin metabolic process rlm1 6.6e-05 117 58 7 GO:0071555 BP cell wall organization rlm1 6.6e-05 117 58 7 GO:0007047 BP cellular cell wall organization rlm1 5.53e-09 9 58 5 GO:0042597 CC periplasmic space rlm1 5.53e-09 9 58 5 GO:0030287 CC cell wall-bounded periplasmic space rlm1 1.93e-05 17 58 4 KEGG:00910 ke Nitrogen metabolism rlm1 1.08e-06 9 58 4 KEGG:00460 ke Cyanoamino acid metabolism rlm1 0.000178 29 58 4 KEGG:00250 ke Alanine, aspartate and glutamate metabolism rlr1 3.34e-05 60 59 6 GO:0055066 BP di-, tri-valent inorganic cation homeostasis rlr1 3.34e-05 60 59 6 GO:0030005 BP cellular di-, tri-valent inorganic cation homeostasis rlr1 5.99e-05 8 59 3 GO:0033212 BP iron assimilation rlr1 0.000627 13 59 3 KEGG:00740 ke Riboflavin metabolism rox1 5.1e-05 24 176 6 GO:0015674 BP di-, tri-valent inorganic cation transport rox1 3.69e-06 16 176 6 GO:0006826 BP iron ion transport rox1 3.52e-06 5 176 4 GO:0034755 BP iron ion transmembrane transport rox1 1.9e-05 53 176 9 GO:0030001 BP metal ion transport rox1 4.6e-05 8 176 4 GO:0033212 BP iron assimilation rox1 2.69e-06 32 176 8 GO:0006312 BP mitotic recombination rox1 1.62e-05 20 176 6 GO:0000722 BP telomere maintenance via recombination rox1 3.62e-05 86 176 11 GO:0006811 BP ion transport rox1 1.38e-05 12 176 5 GO:0005381 MF iron ion transmembrane transporter activity rox1 8.72e-06 37 176 8 GO:0046873 MF metal ion transmembrane transporter activity rox1 6.17e-05 91 176 11 GO:0016491 MF oxidoreductase activity rox1 0.00202 11 176 3 KEGG:00770 ke Pantothenate and CoA biosynthesis rox1 0.000291 616 176 26 KEGG:01100 ke Metabolic pathways rox1 0.000359 15 176 4 KEGG:00100 ke Steroid biosynthesis rph1 7.9e-05 5 372 4 GO:0043562 BP cellular response to nitrogen levels rph1 7.9e-05 5 372 4 GO:0006995 BP cellular response to nitrogen starvation rph1 2.63e-05 402 372 47 GO:0044429 CC mitochondrial part rph1 0.000124 9 372 5 KEGG:00460 ke Cyanoamino acid metabolism rph1 0.000127 19 372 7 KEGG:00480 ke Glutathione metabolism rph1 0.00108 8 372 4 KEGG:00410 ke beta-Alanine metabolism rph1 0.000231 23 372 7 REAC:504350 re Pyruvate metabolism and TCA cycle rph1 5.74e-05 19 372 7 REAC:504351 re Citric acid cycle (TCA cycle) rpi1 0.000143 40 175 7 KEGG:00500 ke Starch and sucrose metabolism rpi1 0.000964 125 175 11 KEGG:04111 ke Cell cycle - yeast rpi1 5.88e-06 8 175 4 REAC:504500 re Glycogen synthesis rpn4 1.56e-05 390 375 46 GO:0042221 BP response to chemical stimulus rpn4 9.05e-07 352 375 46 GO:0009056 BP catabolic process rpn4 9.15e-07 341 375 45 GO:0044248 BP cellular catabolic process rpn4 6.08e-05 30 375 9 GO:0009266 BP response to temperature stimulus rpn4 1.34e-07 133 375 26 GO:0043632 BP modification-dependent macromolecule catabolic process rpn4 1.63e-06 141 375 25 GO:0006508 BP proteolysis rpn4 7.95e-07 145 375 26 GO:0030163 BP protein catabolic process rpn4 8.06e-07 136 375 25 GO:0044257 BP cellular protein catabolic process rpn4 2.82e-07 129 375 25 GO:0051603 BP proteolysis involved in cellular protein catabolic process rpn4 1.75e-07 126 375 25 GO:0019941 BP modification-dependent protein catabolic process rpn4 1.75e-07 126 375 25 GO:0006511 BP ubiquitin-dependent protein catabolic process rpn4 2.75e-24 46 375 29 GO:0000502 CC proteasome complex rpn4 2.21e-15 22 375 16 GO:0022624 CC proteasome accessory complex rpn4 1.21e-12 15 375 12 GO:0005839 CC proteasome core complex rpn4 1.81e-05 7 375 5 GO:0019774 CC proteasome core complex, beta-subunit complex rpn4 3.67e-09 7 375 7 GO:0019773 CC proteasome core complex, alpha-subunit complex rpn4 2.21e-15 22 375 16 GO:0005838 CC proteasome regulatory particle rpn4 3.73e-07 10 375 7 GO:0008541 CC proteasome regulatory particle, lid subcomplex rpn4 1.92e-09 9 375 8 GO:0008540 CC proteasome regulatory particle, base subcomplex rpn4 3.96e-05 12 375 6 GO:0005576 CC extracellular region rpn4 1.5e-05 210 375 30 GO:0005886 CC plasma membrane rpn4 1.7e-07 43 375 14 GO:0008233 MF peptidase activity rpn4 1.21e-07 42 375 14 GO:0070011 MF peptidase activity, acting on L-amino acid peptides rpn4 8.89e-08 20 375 10 GO:0004175 MF endopeptidase activity rpn4 3.25e-28 35 375 28 KEGG:03050 ke Proteasome rpn4 3.43e-24 39 375 27 REAC:504540 re Apoptosis rpn4 3.35e-25 37 375 27 REAC:504756 re Regulation of Apoptosis rpn4 3.35e-25 37 375 27 REAC:504755 re Regulation of activated PAK-2p34 by proteasome mediated degradation rpn4 3.35e-25 37 375 27 REAC:503734 re Proteasome mediated degradation of PAK-2p34 rpn4 6.19e-16 66 375 27 REAC:504575 re DNA Replication rpn4 1.94e-22 43 375 27 REAC:504580 re Regulation of DNA replication rpn4 1.01e-23 40 375 27 REAC:504579 re Removal of licensing factors from origins rpn4 9.71e-12 99 375 28 REAC:504439 re Cell Cycle, Mitotic rpn4 9.89e-16 67 375 27 REAC:504556 re S Phase rpn4 5.04e-17 61 375 27 REAC:504578 re Synthesis of DNA rpn4 1.01e-23 40 375 27 REAC:504577 re Switching of origins to a post-replicative state rpn4 9.47e-26 36 375 27 REAC:504576 re CDK-mediated phosphorylation and removal of Cdc6 rpn4 2.48e-26 35 375 27 REAC:504199 re Ubiquitinated Cdc6 is degraded by the proteasome rpn4 2.48e-26 35 375 27 REAC:504738 re Orc1 removal from chromatin rpn4 2.48e-26 35 375 27 REAC:504203 re Ubiquitinated Orc1 is degraded by the proteasome rpn4 5.95e-21 47 375 27 REAC:504693 re Cell Cycle Checkpoints rpn4 2.48e-26 35 375 27 REAC:504744 re G1/S DNA Damage Checkpoints rpn4 2.48e-26 35 375 27 REAC:504743 re p53-Independent G1/S DNA damage checkpoint rpn4 2.48e-26 35 375 27 REAC:504742 re p53-Independent DNA Damage Response rpn4 2.48e-26 35 375 27 REAC:504757 re Ubiquitin Mediated Degradation of Phosphorylated Cdc25A rpn4 2.48e-26 35 375 27 REAC:503737 re Proteolytic degradation of ubiquitinated-Cdc25A rsc1 4.35e-08 89 684 28 GO:0030312 CC external encapsulating structure rsc1 4.35e-08 89 684 28 GO:0005618 CC cell wall rsc1 4.35e-08 89 684 28 GO:0009277 CC fungal-type cell wall rsc1 3.06e-05 11 684 7 GO:0005199 MF structural constituent of cell wall rsc1 4.14e-05 616 684 87 KEGG:01100 ke Metabolic pathways rsc1 1.05e-05 29 684 12 KEGG:00250 ke Alanine, aspartate and glutamate metabolism rsc1 1.24e-05 17 684 9 KEGG:00910 ke Nitrogen metabolism rsc1 0.00136 49 684 12 REAC:504363 re Metabolism of amino acids rsc1 0.000864 3 684 3 REAC:504403 re Tryptophan catabolism rsc2 6.52e-05 131 741 32 GO:0044283 BP small molecule biosynthetic process rsc2 1.4e-05 60 741 20 GO:0006766 BP vitamin metabolic process rsc2 1.4e-05 60 741 20 GO:0006767 BP water-soluble vitamin metabolic process rsc2 2.85e-08 193 741 51 GO:0034641 BP cellular nitrogen compound metabolic process rsc2 6.78e-05 42 741 15 GO:0043603 BP cellular amide metabolic process rsc2 3.49e-05 40 741 15 GO:0006733 BP oxidoreduction coenzyme metabolic process rsc2 3.97e-05 36 741 14 GO:0019362 BP pyridine nucleotide metabolic process rsc2 0.00116 29 741 11 KEGG:00330 ke Arginine and proline metabolism rtf1 0.00201 4 451 3 KEGG:00061 ke Fatty acid biosynthesis rtf1 3.2e-07 616 451 77 KEGG:01100 ke Metabolic pathways rtf1 4.86e-05 29 451 10 KEGG:00250 ke Alanine, aspartate and glutamate metabolism rtf1 3.46e-05 18 451 8 KEGG:00290 ke Valine, leucine and isoleucine biosynthesis rtg1 0.00221 13 144 3 KEGG:00740 ke Riboflavin metabolism rtg1 0.000466 8 144 3 KEGG:00410 ke beta-Alanine metabolism rtg3 8.21e-06 456 464 61 GO:0044281 BP small molecule metabolic process rtg3 3.87e-05 180 464 30 GO:0042180 BP cellular ketone metabolic process rtg3 2.48e-05 176 464 30 GO:0006082 BP organic acid metabolic process rtg3 2.48e-05 176 464 30 GO:0043436 BP oxoacid metabolic process rtg3 2.48e-05 176 464 30 GO:0019752 BP carboxylic acid metabolic process rtg3 6.13e-07 125 464 27 GO:0006519 BP cellular amino acid and derivative metabolic process rtg3 5e-05 55 464 14 GO:0009309 BP amine biosynthetic process rtg3 8.98e-06 193 464 33 GO:0034641 BP cellular nitrogen compound metabolic process rtg3 1.01e-06 113 464 25 GO:0044106 BP cellular amine metabolic process rtg3 2.26e-07 98 464 24 GO:0006520 BP cellular amino acid metabolic process rtg3 7.04e-06 20 464 9 GO:0009064 BP glutamine family amino acid metabolic process rtg3 5.86e-05 15 464 7 GO:0006536 BP glutamate metabolic process rtg3 1.54e-05 50 464 14 GO:0008652 BP cellular amino acid biosynthetic process rtg3 0.00113 29 464 10 KEGG:00250 ke Alanine, aspartate and glutamate metabolism rtg3 7.77e-11 142 464 44 KEGG:03010 ke Ribosome rtg3 4.52e-05 29 464 12 KEGG:00330 ke Arginine and proline metabolism rtg3 1.75e-10 152 464 47 REAC:504522 re 3' -UTR-mediated translational regulation rtg3 1.75e-10 152 464 47 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression rtg3 4.91e-07 79 464 27 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit rtg3 1.81e-07 200 464 50 REAC:504343 re Metabolism of proteins rtg3 0.000183 259 464 52 REAC:504459 re Gene Expression rtg3 3.69e-09 164 464 47 REAC:504507 re Translation rtg3 1.63e-09 139 464 43 REAC:504506 re Eukaryotic Translation Elongation rtg3 1.63e-09 139 464 43 REAC:504505 re Peptide chain elongation rtg3 9.51e-10 137 464 43 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site rtg3 9.51e-10 137 464 43 REAC:502806 re Hydrolysis of eEF1A:GTP rtg3 5.46e-10 135 464 43 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA rtg3 1.63e-09 139 464 43 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction rtg3 1.09e-09 159 464 47 REAC:504612 re Eukaryotic Translation Initiation rtg3 1.09e-09 159 464 47 REAC:504611 re Cap-dependent Translation Initiation rtg3 0.000587 67 464 19 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex rtg3 0.000587 67 464 19 REAC:502531 re Formation of the 43S pre-initiation complex rtg3 7.22e-10 136 464 43 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit rtg3 7.22e-10 136 464 43 REAC:504077 re The 60S subunit joins the translation initiation complex rtg3 7.22e-10 136 464 43 REAC:502286 re eIF5B:GTP is hydrolyzed and released rtg3 1.66e-10 136 464 44 REAC:504765 re Formation of a pool of free 40S subunits rtg3 1.66e-10 136 464 44 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome rtg3 0.000682 73 464 20 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize rtg3 0.000682 73 464 20 REAC:503952 re Ribosomal scanning sas3 4.35e-29 142 1171 89 KEGG:03010 ke Ribosome sas3 2.1e-16 200 1171 101 REAC:504343 re Metabolism of proteins sas3 1.85e-17 259 1171 122 REAC:504459 re Gene Expression sas3 1.45e-19 164 1171 93 REAC:504507 re Translation sas3 1.02e-20 139 1171 85 REAC:504506 re Eukaryotic Translation Elongation sas3 1.02e-20 139 1171 85 REAC:504505 re Peptide chain elongation sas3 1.5e-20 137 1171 84 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site sas3 1.5e-20 137 1171 84 REAC:502806 re Hydrolysis of eEF1A:GTP sas3 3.47e-21 135 1171 84 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA sas3 1.02e-20 139 1171 85 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction sas3 3.39e-20 159 1171 92 REAC:504612 re Eukaryotic Translation Initiation sas3 3.39e-20 159 1171 92 REAC:504611 re Cap-dependent Translation Initiation sas3 2.89e-06 74 1171 38 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S sas3 2.89e-06 74 1171 38 REAC:504671 re Translation initiation complex formation sas3 6.05e-06 73 1171 37 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize sas3 2.89e-06 74 1171 38 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation sas3 9.21e-06 74 1171 37 REAC:504769 re Ribosomal scanning and start codon recognition sas3 6.05e-06 73 1171 37 REAC:503952 re Ribosomal scanning sas3 9.21e-06 74 1171 37 REAC:504040 re Start codon recognition sas3 1.31e-06 67 1171 36 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex sas3 1.31e-06 67 1171 36 REAC:502531 re Formation of the 43S pre-initiation complex sas3 7.25e-21 136 1171 84 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit sas3 7.25e-21 136 1171 84 REAC:504077 re The 60S subunit joins the translation initiation complex sas3 7.25e-21 136 1171 84 REAC:502286 re eIF5B:GTP is hydrolyzed and released sas3 7.25e-21 136 1171 84 REAC:504765 re Formation of a pool of free 40S subunits sas3 7.25e-21 136 1171 84 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome sas3 1.1e-20 152 1171 90 REAC:504522 re 3' -UTR-mediated translational regulation sas3 1.1e-20 152 1171 90 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression sas3 3.5e-14 79 1171 52 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit sas3 6.31e-07 76 1171 40 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA sas4 1.6e-05 32 129 6 GO:0006312 BP mitotic recombination sas4 8.12e-07 20 129 6 GO:0000722 BP telomere maintenance via recombination sas4 5.19e-05 5 129 3 GO:0046688 BP response to copper ion sas4 5.75e-05 13 129 4 GO:0019438 BP aromatic compound biosynthetic process sas4 1.76e-05 10 129 4 GO:0042723 BP thiamin and derivative metabolic process sas4 3.05e-06 7 129 4 GO:0042724 BP thiamin and derivative biosynthetic process sas4 1.07e-05 9 129 4 GO:0006772 BP thiamin metabolic process sas4 3.05e-06 7 129 4 GO:0009228 BP thiamin biosynthetic process sas4 8.2e-08 23 129 7 GO:0009636 BP response to toxin sas4 7.61e-05 60 129 7 GO:0055066 BP di-, tri-valent inorganic cation homeostasis sas4 7.61e-05 60 129 7 GO:0030005 BP cellular di-, tri-valent inorganic cation homeostasis sas4 6.03e-06 8 129 4 GO:0042816 BP vitamin B6 metabolic process sas4 6.03e-06 8 129 4 GO:0008614 BP pyridoxine metabolic process sas4 9.9e-07 32 129 7 GO:0003678 MF DNA helicase activity sas4 0.000119 22 129 4 KEGG:00650 ke Butanoate metabolism sas4 0.000274 27 129 4 KEGG:00051 ke Fructose and mannose metabolism sas5 7.12e-06 23 323 8 GO:0009636 BP response to toxin sds3 7.82e-05 346 612 51 GO:0030529 CC ribonucleoprotein complex sds3 3.91e-06 137 612 29 GO:0003723 MF RNA binding sds3 6.91e-05 39 612 12 GO:0015077 MF monovalent inorganic cation transmembrane transporter activity sds3 2.81e-05 36 612 12 GO:0015078 MF hydrogen ion transmembrane transporter activity sds3 1.11e-55 142 612 92 KEGG:03010 ke Ribosome sds3 9.42e-34 200 612 90 REAC:504343 re Metabolism of proteins sds3 4.83e-30 259 612 98 REAC:504459 re Gene Expression sds3 1.51e-38 164 612 86 REAC:504507 re Translation sds3 1.41e-45 139 612 85 REAC:504506 re Eukaryotic Translation Elongation sds3 1.41e-45 139 612 85 REAC:504505 re Peptide chain elongation sds3 2.41e-46 137 612 85 REAC:502806 re Hydrolysis of eEF1A:GTP sds3 2.41e-46 137 612 85 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site sds3 3.91e-47 135 612 85 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA sds3 1.41e-45 139 612 85 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction sds3 4.82e-40 159 612 86 REAC:504612 re Eukaryotic Translation Initiation sds3 4.82e-40 159 612 86 REAC:504611 re Cap-dependent Translation Initiation sds3 1.91e-13 74 612 37 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S sds3 1.91e-13 74 612 37 REAC:504671 re Translation initiation complex formation sds3 1.08e-13 73 612 37 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize sds3 1.91e-13 74 612 37 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation sds3 2.63e-15 67 612 37 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex sds3 2.63e-15 67 612 37 REAC:502531 re Formation of the 43S pre-initiation complex sds3 1.91e-13 74 612 37 REAC:504769 re Ribosomal scanning and start codon recognition sds3 1.08e-13 73 612 37 REAC:503952 re Ribosomal scanning sds3 1.91e-13 74 612 37 REAC:504040 re Start codon recognition sds3 9.76e-47 136 612 85 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit sds3 9.76e-47 136 612 85 REAC:504077 re The 60S subunit joins the translation initiation complex sds3 9.76e-47 136 612 85 REAC:502286 re eIF5B:GTP is hydrolyzed and released sds3 4.02e-48 136 612 86 REAC:504765 re Formation of a pool of free 40S subunits sds3 4.02e-48 136 612 86 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome sds3 2.81e-42 152 612 86 REAC:504522 re 3' -UTR-mediated translational regulation sds3 2.81e-42 152 612 86 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression sds3 7.57e-24 79 612 49 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit sds3 8.1e-14 76 612 38 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA sef1 8.92e-05 619 252 46 GO:0044085 BP cellular component biogenesis sef1 6.98e-06 328 252 32 GO:0022613 BP ribonucleoprotein complex biogenesis sef1 1.54e-06 306 252 32 GO:0042254 BP ribosome biogenesis sef1 9.14e-05 141 252 17 GO:0007005 BP mitochondrion organization sef1 1.58e-05 5 252 4 GO:0043562 BP cellular response to nitrogen levels sef1 1.58e-05 5 252 4 GO:0006995 BP cellular response to nitrogen starvation sef1 0.00087 142 252 16 KEGG:03010 ke Ribosome sef1 0.000551 9 252 4 KEGG:00460 ke Cyanoamino acid metabolism sef1 0.000387 159 252 20 REAC:504612 re Eukaryotic Translation Initiation sef1 0.000387 159 252 20 REAC:504611 re Cap-dependent Translation Initiation set2 0.000128 29 331 8 KEGG:00330 ke Arginine and proline metabolism set2 0.000261 616 331 51 KEGG:01100 ke Metabolic pathways set2 0.00102 15 331 5 KEGG:00340 ke Histidine metabolism set2 7.34e-06 8 331 5 REAC:504416 re Synaptic Transmission set2 7.34e-06 8 331 5 REAC:504415 re Transmission across Chemical Synapses set2 0.000331 4 331 3 REAC:504414 re Neurotransmitter Clearance In The Synaptic Cleft set2 0.000331 4 331 3 REAC:504413 re Serotonin clearance from the synaptic cleft set2 0.000331 4 331 3 REAC:504412 re Metabolism of serotonin set2 0.000331 4 331 3 REAC:499890 re 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid set2 0.000331 4 331 3 REAC:504423 re Aldehyde Dehydrogenase set2 0.000331 4 331 3 REAC:504422 re Acetaldehyde is oxidized by NAD+ to form acetate, NADH, and H+ set2 0.000331 4 331 3 REAC:500035 re Acetaldehyde + NAD+ <=> Acetate + NADH + H+ [mitochondrial] set2 0.000331 4 331 3 REAC:500034 re Acetaldehyde + NAD+ <=> Acetate + NADH + H+ [cytosolic] set2 5.01e-05 6 331 4 REAC:504607 re Glycogen breakdown (glycogenolysis) sfl1 5.11e-05 6 89 3 GO:0015688 BP iron chelate transport sfl1 5.11e-05 6 89 3 GO:0033214 BP iron assimilation by chelation and transport sfl1 5.63e-08 9 89 5 GO:0015891 BP siderophore transport sfl1 5.11e-05 6 89 3 GO:0015892 BP siderophore-iron transport sfl1 0.000661 29 89 4 KEGG:00330 ke Arginine and proline metabolism sfp1 4.91e-08 328 2053 157 GO:0022613 BP ribonucleoprotein complex biogenesis sfp1 1.4e-08 306 2053 150 GO:0042254 BP ribosome biogenesis sfp1 2.04e-06 70 2053 43 GO:0070925 BP organelle assembly sfp1 7.71e-07 60 2053 39 GO:0042255 BP ribosome assembly sfp1 1.67e-06 51 2053 34 GO:0042257 BP ribosomal subunit assembly sfp1 4.54e-41 142 2053 132 KEGG:03010 ke Ribosome sfp1 2.27e-26 200 2053 158 REAC:504343 re Metabolism of proteins sfp1 5.2e-26 259 2053 191 REAC:504459 re Gene Expression sfp1 2.85e-36 164 2053 146 REAC:504507 re Translation sfp1 5.29e-35 139 2053 128 REAC:504506 re Eukaryotic Translation Elongation sfp1 5.29e-35 139 2053 128 REAC:504505 re Peptide chain elongation sfp1 1.64e-35 137 2053 127 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site sfp1 1.64e-35 137 2053 127 REAC:502806 re Hydrolysis of eEF1A:GTP sfp1 4.72e-36 135 2053 126 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA sfp1 5.29e-35 139 2053 128 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction sfp1 7.63e-38 159 2053 144 REAC:504612 re Eukaryotic Translation Initiation sfp1 7.63e-38 159 2053 144 REAC:504611 re Cap-dependent Translation Initiation sfp1 1.36e-16 74 2053 67 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S sfp1 1.36e-16 74 2053 67 REAC:504671 re Translation initiation complex formation sfp1 2.89e-16 73 2053 66 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize sfp1 1.36e-16 74 2053 67 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation sfp1 1.36e-16 74 2053 67 REAC:504769 re Ribosomal scanning and start codon recognition sfp1 2.89e-16 73 2053 66 REAC:503952 re Ribosomal scanning sfp1 1.36e-16 74 2053 67 REAC:504040 re Start codon recognition sfp1 2.12e-15 67 2053 61 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex sfp1 2.12e-15 67 2053 61 REAC:502531 re Formation of the 43S pre-initiation complex sfp1 1.92e-36 136 2053 127 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit sfp1 1.92e-36 136 2053 127 REAC:504077 re The 60S subunit joins the translation initiation complex sfp1 1.92e-36 136 2053 127 REAC:502286 re eIF5B:GTP is hydrolyzed and released sfp1 4e-35 136 2053 126 REAC:504765 re Formation of a pool of free 40S subunits sfp1 4e-35 136 2053 126 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome sfp1 4.01e-40 152 2053 141 REAC:504522 re 3' -UTR-mediated translational regulation sfp1 4.01e-40 152 2053 141 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression sfp1 5.79e-22 79 2053 75 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit sfp1 3e-17 76 2053 69 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA sif2 5.48e-05 180 431 28 GO:0042180 BP cellular ketone metabolic process sif2 3.61e-05 176 431 28 GO:0006082 BP organic acid metabolic process sif2 3.61e-05 176 431 28 GO:0043436 BP oxoacid metabolic process sif2 3.61e-05 176 431 28 GO:0019752 BP carboxylic acid metabolic process sif2 1.93e-05 55 431 14 GO:0009309 BP amine biosynthetic process sif2 1.11e-05 193 431 31 GO:0034641 BP cellular nitrogen compound metabolic process sif2 2.92e-06 113 431 23 GO:0044106 BP cellular amine metabolic process sif2 1.51e-06 125 431 25 GO:0006519 BP cellular amino acid and derivative metabolic process sif2 8.44e-07 98 431 22 GO:0006520 BP cellular amino acid metabolic process sif2 3e-05 50 431 13 GO:0008652 BP cellular amino acid biosynthetic process sif2 0.00184 29 431 8 KEGG:00330 ke Arginine and proline metabolism sif2 0.000322 13 431 6 KEGG:00300 ke Lysine biosynthesis sif2 0.000719 616 431 69 KEGG:01100 ke Metabolic pathways sif2 0.00116 11 431 5 KEGG:00360 ke Phenylalanine metabolism sin3 2.29e-08 456 1793 187 GO:0044281 BP small molecule metabolic process sin3 9.55e-06 131 1793 62 GO:0044283 BP small molecule biosynthetic process sin3 1.8e-06 113 1793 57 GO:0055086 BP cellular nucleobase, nucleoside and nucleotide metabolic process sin3 2.65e-06 79 1793 43 GO:0006753 BP nucleoside phosphate metabolic process sin3 2.65e-06 79 1793 43 GO:0009117 BP nucleotide metabolic process sin3 1.85e-06 47 1793 34 KEGG:00010 ke Glycolysis / Gluconeogenesis sin3 1.32e-35 142 1793 123 KEGG:03010 ke Ribosome sin3 1.35e-30 152 1793 132 REAC:504522 re 3' -UTR-mediated translational regulation sin3 1.35e-30 152 1793 132 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression sin3 9.77e-19 79 1793 72 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit sin3 5.28e-12 76 1793 63 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA sin3 1.58e-23 200 1793 153 REAC:504343 re Metabolism of proteins sin3 8.25e-15 259 1793 171 REAC:504459 re Gene Expression sin3 5.95e-30 164 1793 139 REAC:504507 re Translation sin3 6.46e-27 139 1793 120 REAC:504506 re Eukaryotic Translation Elongation sin3 6.46e-27 139 1793 120 REAC:504505 re Peptide chain elongation sin3 3.23e-27 137 1793 119 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site sin3 3.23e-27 137 1793 119 REAC:502806 re Hydrolysis of eEF1A:GTP sin3 1.56e-27 135 1793 118 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA sin3 6.46e-27 139 1793 120 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction sin3 4.07e-31 159 1793 137 REAC:504612 re Eukaryotic Translation Initiation sin3 4.07e-31 159 1793 137 REAC:504611 re Cap-dependent Translation Initiation sin3 2.01e-11 74 1793 61 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S sin3 2.01e-11 74 1793 61 REAC:504671 re Translation initiation complex formation sin3 6.06e-12 73 1793 61 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize sin3 2.01e-11 74 1793 61 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation sin3 3.07e-12 74 1793 62 REAC:504769 re Ribosomal scanning and start codon recognition sin3 6.06e-12 73 1793 61 REAC:503952 re Ribosomal scanning sin3 3.07e-12 74 1793 62 REAC:504040 re Start codon recognition sin3 3.26e-10 67 1793 55 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex sin3 3.26e-10 67 1793 55 REAC:502531 re Formation of the 43S pre-initiation complex sin3 7.35e-27 136 1793 118 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit sin3 7.35e-27 136 1793 118 REAC:504077 re The 60S subunit joins the translation initiation complex sin3 7.35e-27 136 1793 118 REAC:502286 re eIF5B:GTP is hydrolyzed and released sin3 6.83e-28 136 1793 119 REAC:504765 re Formation of a pool of free 40S subunits sin3 6.83e-28 136 1793 119 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome sir1 6.31e-05 3 292 3 GO:0031684 BP heterotrimeric G-protein complex cycle sir1 8.52e-05 28 292 7 GO:0032005 BP signal transduction involved in conjugation with cellular fusion sir1 4.85e-05 158 292 18 GO:0010033 BP response to organic substance sir1 1.04e-05 90 292 14 GO:0019236 BP response to pheromone sir1 1.71e-06 67 292 13 GO:0000749 BP response to pheromone during conjugation with cellular fusion sir1 8.52e-05 28 292 7 GO:0000750 BP pheromone-dependent signal transduction involved in conjugation with cellular fusion sir1 0.000447 125 292 13 KEGG:04111 ke Cell cycle - yeast sir1 0.000127 55 292 9 KEGG:04011 ke MAPK signaling pathway - yeast sir2 9.05e-44 142 1482 113 KEGG:03010 ke Ribosome sir2 1.84e-22 200 1482 120 REAC:504343 re Metabolism of proteins sir2 9.6e-21 259 1482 140 REAC:504459 re Gene Expression sir2 2.95e-27 164 1482 111 REAC:504507 re Translation sir2 1.72e-33 139 1482 106 REAC:504506 re Eukaryotic Translation Elongation sir2 1.72e-33 139 1482 106 REAC:504505 re Peptide chain elongation sir2 1.56e-34 137 1482 106 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site sir2 1.56e-34 137 1482 106 REAC:502806 re Hydrolysis of eEF1A:GTP sir2 1.28e-35 135 1482 106 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA sir2 1.72e-33 139 1482 106 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction sir2 3.17e-29 159 1482 111 REAC:504612 re Eukaryotic Translation Initiation sir2 3.17e-29 159 1482 111 REAC:504611 re Cap-dependent Translation Initiation sir2 9.17e-11 74 1482 49 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S sir2 9.17e-11 74 1482 49 REAC:504671 re Translation initiation complex formation sir2 2.18e-10 73 1482 48 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize sir2 9.17e-11 74 1482 49 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation sir2 4.52e-10 74 1482 48 REAC:504769 re Ribosomal scanning and start codon recognition sir2 2.18e-10 73 1482 48 REAC:503952 re Ribosomal scanning sir2 4.52e-10 74 1482 48 REAC:504040 re Start codon recognition sir2 9.58e-12 67 1482 47 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex sir2 9.58e-12 67 1482 47 REAC:502531 re Formation of the 43S pre-initiation complex sir2 4.53e-35 136 1482 106 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit sir2 4.53e-35 136 1482 106 REAC:504077 re The 60S subunit joins the translation initiation complex sir2 4.53e-35 136 1482 106 REAC:502286 re eIF5B:GTP is hydrolyzed and released sir2 4.53e-35 136 1482 106 REAC:504765 re Formation of a pool of free 40S subunits sir2 4.53e-35 136 1482 106 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome sir2 2.76e-31 152 1482 110 REAC:504522 re 3' -UTR-mediated translational regulation sir2 2.76e-31 152 1482 110 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression sir2 1.01e-18 79 1482 61 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit sir2 1.57e-11 76 1482 51 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA sir3 1.59e-05 328 856 69 GO:0022613 BP ribonucleoprotein complex biogenesis sir3 1.04e-05 306 856 66 GO:0042254 BP ribosome biogenesis sir3 4.71e-05 55 856 19 KEGG:04011 ke MAPK signaling pathway - yeast smk1 0.000882 10 113 3 KEGG:00280 ke Valine, leucine and isoleucine degradation snf1 6.18e-05 32 267 8 GO:0008643 BP carbohydrate transport snf1 4.54e-05 23 267 7 GO:0015749 BP monosaccharide transport snf1 4.54e-05 23 267 7 GO:0008645 BP hexose transport snf1 7.28e-05 72 267 12 GO:0008610 BP lipid biosynthetic process snf1 1.64e-06 335 267 35 GO:0031975 CC envelope snf1 1.64e-06 335 267 35 GO:0031967 CC organelle envelope snf1 9.78e-06 33 267 9 GO:0031970 CC organelle envelope lumen snf1 1.34e-05 789 267 60 GO:0005739 CC mitochondrion snf1 4.15e-08 402 267 43 GO:0044429 CC mitochondrial part snf1 4.71e-07 262 267 31 GO:0005740 CC mitochondrial envelope snf1 4.6e-05 91 267 14 GO:0016491 MF oxidoreductase activity snf1 3.73e-05 10 267 5 GO:0016675 MF oxidoreductase activity, acting on heme group of donors snf1 3.73e-05 10 267 5 GO:0016676 MF oxidoreductase activity, acting on heme group of donors, oxygen as acceptor snf1 3.73e-05 10 267 5 GO:0015002 MF heme-copper terminal oxidase activity snf1 3.73e-05 10 267 5 GO:0004129 MF cytochrome-c oxidase activity snf1 1.84e-06 21 267 8 GO:0015144 MF carbohydrate transmembrane transporter activity snf1 7.39e-07 19 267 8 GO:0051119 MF sugar transmembrane transporter activity snf1 4.55e-06 17 267 7 GO:0015145 MF monosaccharide transmembrane transporter activity snf1 4.55e-06 17 267 7 GO:0015149 MF hexose transmembrane transporter activity snf1 2.78e-06 16 267 7 GO:0005355 MF glucose transmembrane transporter activity snf1 2.79e-05 15 267 6 GO:0015578 MF mannose transmembrane transporter activity snf1 2.79e-05 15 267 6 GO:0005353 MF fructose transmembrane transporter activity snf1 0.00137 616 267 44 KEGG:01100 ke Metabolic pathways snf11 9.11e-09 9 170 6 GO:0042597 CC periplasmic space snf11 9.11e-09 9 170 6 GO:0030287 CC cell wall-bounded periplasmic space snf11 0.00027 29 170 5 KEGG:00250 ke Alanine, aspartate and glutamate metabolism snf11 0.000689 9 170 3 KEGG:00460 ke Cyanoamino acid metabolism snf11 0.000109 13 170 4 KEGG:00740 ke Riboflavin metabolism spt10 2.67e-07 203 1780 90 GO:0034660 BP ncRNA metabolic process spt10 1.57e-08 124 1780 64 GO:0016072 BP rRNA metabolic process spt10 1.66e-06 190 1780 83 GO:0034470 BP ncRNA processing spt10 8.53e-07 70 1780 39 GO:0070925 BP organelle assembly spt10 2.2e-12 328 1780 149 GO:0022613 BP ribonucleoprotein complex biogenesis spt10 1.09e-14 306 1780 147 GO:0042254 BP ribosome biogenesis spt10 1.01e-08 60 1780 38 GO:0042255 BP ribosome assembly spt10 4.44e-08 51 1780 33 GO:0042257 BP ribosomal subunit assembly spt10 7.66e-08 115 1780 59 GO:0006364 BP rRNA processing spt10 1.23e-06 61 1780 35 GO:0042273 BP ribosomal large subunit biogenesis spt10 3.57e-06 193 1780 83 GO:0034641 BP cellular nitrogen compound metabolic process spt10 1.03e-05 9 1780 9 GO:0006207 BP 'de novo' pyrimidine base biosynthetic process spt10 2.27e-06 456 1780 171 GO:0044281 BP small molecule metabolic process spt10 7.28e-07 113 1780 56 GO:0055086 BP cellular nucleobase, nucleoside and nucleotide metabolic process spt10 1.42e-05 16 1780 13 GO:0009123 BP nucleoside monophosphate metabolic process spt10 3.58e-06 15 1780 13 GO:0009126 BP purine nucleoside monophosphate metabolic process spt10 1.12e-05 14 1780 12 GO:0009167 BP purine ribonucleoside monophosphate metabolic process spt10 7.99e-07 11 1780 11 GO:0000786 CC nucleosome spt10 7.99e-07 11 1780 11 GO:0000788 CC nuclear nucleosome spt10 3.81e-08 53 1780 34 GO:0030684 CC preribosome spt10 7.92e-53 142 1780 134 KEGG:03010 ke Ribosome spt10 4.39e-37 200 1780 163 REAC:504343 re Metabolism of proteins spt10 1.1e-25 259 1780 181 REAC:504459 re Gene Expression spt10 2.67e-42 164 1780 146 REAC:504507 re Translation spt10 3.1e-40 139 1780 128 REAC:504506 re Eukaryotic Translation Elongation spt10 3.1e-40 139 1780 128 REAC:504505 re Peptide chain elongation spt10 3.97e-42 137 1780 128 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site spt10 3.97e-42 137 1780 128 REAC:502806 re Hydrolysis of eEF1A:GTP spt10 1.1e-42 135 1780 127 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA spt10 3.1e-40 139 1780 128 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction spt10 3.69e-45 159 1780 145 REAC:504612 re Eukaryotic Translation Initiation spt10 3.69e-45 159 1780 145 REAC:504611 re Cap-dependent Translation Initiation spt10 5.17e-19 74 1780 67 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S spt10 5.17e-19 74 1780 67 REAC:504671 re Translation initiation complex formation spt10 1.21e-18 73 1780 66 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize spt10 5.17e-19 74 1780 67 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation spt10 5.17e-19 74 1780 67 REAC:504769 re Ribosomal scanning and start codon recognition spt10 1.21e-18 73 1780 66 REAC:503952 re Ribosomal scanning spt10 5.17e-19 74 1780 67 REAC:504040 re Start codon recognition spt10 8.3e-19 67 1780 62 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex spt10 8.3e-19 67 1780 62 REAC:502531 re Formation of the 43S pre-initiation complex spt10 1.11e-41 136 1780 127 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit spt10 1.11e-41 136 1780 127 REAC:504077 re The 60S subunit joins the translation initiation complex spt10 1.11e-41 136 1780 127 REAC:502286 re eIF5B:GTP is hydrolyzed and released spt10 3.9e-43 136 1780 128 REAC:504765 re Formation of a pool of free 40S subunits spt10 3.9e-43 136 1780 128 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome spt10 4.51e-46 152 1780 141 REAC:504522 re 3' -UTR-mediated translational regulation spt10 4.51e-46 152 1780 141 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression spt10 8.06e-25 79 1780 75 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit spt10 9.31e-20 76 1780 69 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA spt2 8.22e-06 152 351 23 REAC:504522 re 3' -UTR-mediated translational regulation spt2 8.22e-06 152 351 23 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression spt2 8.19e-06 200 351 27 REAC:504343 re Metabolism of proteins spt2 5.02e-05 259 351 30 REAC:504459 re Gene Expression spt2 8.64e-06 164 351 24 REAC:504507 re Translation spt2 0.000331 139 351 19 REAC:504506 re Eukaryotic Translation Elongation spt2 0.000331 139 351 19 REAC:504505 re Peptide chain elongation spt2 0.00027 137 351 19 REAC:502806 re Hydrolysis of eEF1A:GTP spt2 0.00027 137 351 19 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site spt2 0.000219 135 351 19 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA spt2 0.000331 139 351 19 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction spt2 4.75e-06 159 351 24 REAC:504612 re Eukaryotic Translation Initiation spt2 4.75e-06 159 351 24 REAC:504611 re Cap-dependent Translation Initiation spt2 0.000244 136 351 19 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit spt2 0.000244 136 351 19 REAC:504077 re The 60S subunit joins the translation initiation complex spt2 0.000244 136 351 19 REAC:502286 re eIF5B:GTP is hydrolyzed and released spt2 6.98e-05 136 351 20 REAC:504765 re Formation of a pool of free 40S subunits spt2 6.98e-05 136 351 20 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome spt4 1.02e-07 1796 1417 478 GO:0044444 CC cytoplasmic part spt4 2.89e-17 142 1417 80 KEGG:03010 ke Ribosome spt4 1.43e-12 152 1417 82 REAC:504522 re 3' -UTR-mediated translational regulation spt4 1.43e-12 152 1417 82 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression spt4 4.31e-09 79 1417 47 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit spt4 3.21e-11 200 1417 97 REAC:504343 re Metabolism of proteins spt4 1.34e-12 259 1417 120 REAC:504459 re Gene Expression spt4 9.88e-12 164 1417 85 REAC:504507 re Translation spt4 3.57e-13 139 1417 78 REAC:504506 re Eukaryotic Translation Elongation spt4 3.57e-13 139 1417 78 REAC:504505 re Peptide chain elongation spt4 4.82e-13 137 1417 77 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site spt4 4.82e-13 137 1417 77 REAC:502806 re Hydrolysis of eEF1A:GTP spt4 1.57e-13 135 1417 77 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA spt4 3.57e-13 139 1417 78 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction spt4 3.32e-12 159 1417 84 REAC:504612 re Eukaryotic Translation Initiation spt4 3.32e-12 159 1417 84 REAC:504611 re Cap-dependent Translation Initiation spt4 2.77e-13 136 1417 77 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit spt4 2.77e-13 136 1417 77 REAC:504077 re The 60S subunit joins the translation initiation complex spt4 2.77e-13 136 1417 77 REAC:502286 re eIF5B:GTP is hydrolyzed and released spt4 2.77e-13 136 1417 77 REAC:504765 re Formation of a pool of free 40S subunits spt4 2.77e-13 136 1417 77 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome srb2 2.24e-05 221 815 51 GO:0005783 CC endoplasmic reticulum srb2 1.82e-05 9 815 7 GO:0042597 CC periplasmic space srb2 1.82e-05 9 815 7 GO:0030287 CC cell wall-bounded periplasmic space srb2 3.9e-05 29 815 14 KEGG:00330 ke Arginine and proline metabolism srb2 0.00117 616 815 120 KEGG:01100 ke Metabolic pathways srb2 0.000843 29 815 12 KEGG:00510 ke N-Glycan biosynthesis srb2 0.000843 29 815 12 KEGG:00250 ke Alanine, aspartate and glutamate metabolism srb2 0.00442 29 815 10 REAC:504358 re Metabolism of vitamins and cofactors srb2 0.00442 29 815 10 REAC:504357 re Metabolism of water-soluble vitamins and cofactors srb2 0.00757 10 815 5 REAC:504404 re Nicotinate metabolism srb2 0.000169 49 815 17 REAC:504363 re Metabolism of amino acids srb2 0.000206 11 815 7 REAC:504513 re Ornithine and proline metabolism srb2 0.00284 3 815 3 REAC:504701 re Proline synthesis srb2 0.000397 4 815 4 REAC:504676 re Proline catabolism srb2 0.00188 11 815 6 REAC:504510 re Golgi to ER Retrograde Transport srb2 0.00188 11 815 6 REAC:504509 re COPI Mediated Transport srb2 0.000438 9 815 6 REAC:501739 re Coatomer:Arf1-GTP:GAP lattice formation on golgi membrane srb2 0.000165 8 815 6 REAC:501734 re Coat Complex Formation srb2 0.000438 9 815 6 REAC:502575 re GAP Recruitment to the Coatomer:Arf1-GTP Complex srb2 0.000438 9 815 6 REAC:502796 re Hydrolysis of Arf1-GTP to Arf1-GDP srb2 0.000438 9 815 6 REAC:502113 re Diffusion of inactive Arf1-GDP from membrane srb5 0.000221 13 49 3 KEGG:00740 ke Riboflavin metabolism srb8 6.57e-05 9 567 6 KEGG:00460 ke Cyanoamino acid metabolism srb8 5.85e-05 29 567 11 KEGG:00250 ke Alanine, aspartate and glutamate metabolism srb8 4.27e-05 616 567 86 KEGG:01100 ke Metabolic pathways ssn2 9.59e-06 456 308 46 GO:0044281 BP small molecule metabolic process ssn2 4.67e-05 34 308 9 GO:0006333 BP chromatin assembly or disassembly ssn2 8.05e-09 11 308 8 GO:0000786 CC nucleosome ssn2 8.05e-09 11 308 8 GO:0000788 CC nuclear nucleosome ssn2 1.31e-05 89 308 16 GO:0030312 CC external encapsulating structure ssn2 1.31e-05 89 308 16 GO:0005618 CC cell wall ssn2 1.31e-05 89 308 16 GO:0009277 CC fungal-type cell wall ssn2 0.000166 40 308 10 KEGG:00500 ke Starch and sucrose metabolism ssn2 0.000464 23 308 7 KEGG:00260 ke Glycine, serine and threonine metabolism ssn3 0.00195 29 90 4 KEGG:00330 ke Arginine and proline metabolism ssn3 6.59e-05 8 90 3 REAC:504362 re Urea synthesis stb1 4.86e-05 60 319 12 GO:0055066 BP di-, tri-valent inorganic cation homeostasis stb1 5.48e-05 35 319 9 GO:0055072 BP iron ion homeostasis stb1 4.86e-05 60 319 12 GO:0030005 BP cellular di-, tri-valent inorganic cation homeostasis stb1 5.48e-05 35 319 9 GO:0006879 BP cellular iron ion homeostasis stb1 5e-07 8 319 6 GO:0033212 BP iron assimilation stb1 2.18e-06 6 319 5 GO:0033214 BP iron assimilation by chelation and transport stb1 4.39e-10 9 319 8 GO:0015891 BP siderophore transport stb1 1.69e-06 24 319 9 GO:0015674 BP di-, tri-valent inorganic cation transport stb1 7.04e-05 53 319 11 GO:0030001 BP metal ion transport stb1 6.61e-06 42 319 11 GO:0000041 BP transition metal ion transport stb1 4.55e-07 16 319 8 GO:0006826 BP iron ion transport stb1 2.18e-06 6 319 5 GO:0015688 BP iron chelate transport stb1 2.18e-06 6 319 5 GO:0015892 BP siderophore-iron transport stb1 7.42e-06 28 319 9 GO:0046915 MF transition metal ion transmembrane transporter activity stb1 1.92e-05 268 319 31 GO:0005215 MF transporter activity stb1 7.37e-06 4 319 4 GO:0042927 MF siderophore transporter activity stb1 4.81e-06 214 319 28 GO:0022857 MF transmembrane transporter activity stb1 1.59e-05 191 319 25 GO:0022891 MF substrate-specific transmembrane transporter activity stb1 3.29e-05 33 319 9 GO:0015082 MF di-, tri-valent inorganic cation transmembrane transporter activity stb1 6.31e-07 12 319 7 GO:0005381 MF iron ion transmembrane transporter activity stb1 7.37e-06 4 319 4 GO:0015343 MF siderophore-iron transmembrane transporter activity stb1 0.00153 5 319 3 KEGG:00590 ke Arachidonic acid metabolism stb2 0.000132 29 181 6 KEGG:00330 ke Arginine and proline metabolism stb2 7.1e-05 49 181 8 REAC:504363 re Metabolism of amino acids stb2 9.42e-06 11 181 5 REAC:504513 re Ornithine and proline metabolism stb2 5.43e-05 8 181 4 REAC:504512 re Ornithine metabolism stb3 0.0019 13 35 2 KEGG:00740 ke Riboflavin metabolism stb6 0.000627 13 91 3 KEGG:00740 ke Riboflavin metabolism stp1 2.11e-05 6 502 5 GO:0033214 BP iron assimilation by chelation and transport stp1 2.11e-05 6 502 5 GO:0015688 BP iron chelate transport stp1 1.7e-08 9 502 8 GO:0015891 BP siderophore transport stp1 2.11e-05 6 502 5 GO:0015892 BP siderophore-iron transport stp1 2.11e-05 180 502 32 GO:0042180 BP cellular ketone metabolic process stp1 3.42e-06 113 502 25 GO:0044106 BP cellular amine metabolic process stp1 3.43e-05 176 502 31 GO:0006082 BP organic acid metabolic process stp1 3.43e-05 176 502 31 GO:0043436 BP oxoacid metabolic process stp1 3.43e-05 176 502 31 GO:0019752 BP carboxylic acid metabolic process stp1 2.91e-06 65 502 18 GO:0016053 BP organic acid biosynthetic process stp1 2.91e-06 65 502 18 GO:0046394 BP carboxylic acid biosynthetic process stp1 2.25e-05 125 502 25 GO:0006519 BP cellular amino acid and derivative metabolic process stp1 7.73e-07 98 502 24 GO:0006520 BP cellular amino acid metabolic process stp1 3.26e-05 50 502 14 GO:0008652 BP cellular amino acid biosynthetic process stp1 7.83e-09 11 502 9 GO:0000786 CC nucleosome stp1 7.83e-09 11 502 9 GO:0000788 CC nuclear nucleosome stp1 1.9e-06 89 502 22 GO:0030312 CC external encapsulating structure stp1 1.9e-06 89 502 22 GO:0005618 CC cell wall stp1 1.9e-06 89 502 22 GO:0009277 CC fungal-type cell wall stp1 1.05e-05 91 502 21 GO:0016491 MF oxidoreductase activity stp1 2.77e-05 268 502 42 GO:0005215 MF transporter activity stp1 7.82e-05 244 502 38 GO:0022892 MF substrate-specific transporter activity stp1 4.6e-05 4 502 4 GO:0042927 MF siderophore transporter activity stp1 4.6e-05 4 502 4 GO:0015343 MF siderophore-iron transmembrane transporter activity stp1 3.54e-06 214 502 38 GO:0022857 MF transmembrane transporter activity stp1 2.88e-05 191 502 33 GO:0022891 MF substrate-specific transmembrane transporter activity stp1 3.52e-06 99 502 23 GO:0015075 MF ion transmembrane transporter activity stp1 1.51e-05 86 502 20 GO:0008324 MF cation transmembrane transporter activity stp1 0.00101 19 502 7 KEGG:00450 ke Selenoamino acid metabolism stp1 0.000805 29 502 9 KEGG:00250 ke Alanine, aspartate and glutamate metabolism stp1 0.00104 616 502 75 KEGG:01100 ke Metabolic pathways stp1 4.01e-06 13 502 8 KEGG:00920 ke Sulfur metabolism stp1 0.000152 29 502 10 KEGG:00270 ke Cysteine and methionine metabolism stp1 3.72e-05 49 502 13 REAC:504363 re Metabolism of amino acids stp2 8.27e-06 11 161 5 GO:0005199 MF structural constituent of cell wall stp2 0.000385 2 161 2 REAC:500635 re alpha-ketoglutarate + NH4+ + NADPH + H+ => glutamate + NADP+ stp2 0.000385 2 161 2 REAC:502635 re glutamate + NAD+ => alpha-ketoglutarate + NH4+ + NADH + H+ sum1 1.86e-05 42 524 13 GO:0043603 BP cellular amide metabolic process sum1 5.55e-05 40 524 12 GO:0006733 BP oxidoreduction coenzyme metabolic process sum1 3.77e-06 60 524 17 GO:0006766 BP vitamin metabolic process sum1 3.77e-06 60 524 17 GO:0006767 BP water-soluble vitamin metabolic process sum1 1.02e-05 40 524 13 GO:0019748 BP secondary metabolic process sum1 1.21e-05 35 524 12 GO:0009820 BP alkaloid metabolic process sum1 1.69e-05 36 524 12 GO:0019362 BP pyridine nucleotide metabolic process sum1 1.21e-05 35 524 12 GO:0046496 BP nicotinamide nucleotide metabolic process sum1 1.21e-05 35 524 12 GO:0006769 BP nicotinamide metabolic process sum1 7.51e-06 133 524 27 GO:0030154 BP cell differentiation sum1 5.6e-05 156 524 28 GO:0071554 BP cell wall organization or biogenesis sum1 1.12e-06 114 524 26 GO:0043934 BP sporulation sum1 1.46e-07 117 524 28 GO:0045229 BP external encapsulating structure organization sum1 5.71e-05 215 524 35 GO:0019953 BP sexual reproduction sum1 5.6e-05 156 524 28 GO:0070882 BP cellular cell wall organization or biogenesis sum1 3.14e-07 81 524 22 GO:0042546 BP cell wall biogenesis sum1 1.37e-11 51 524 22 GO:0009272 BP fungal-type cell wall biogenesis sum1 9.28e-07 106 524 25 GO:0048468 BP cell development sum1 1.05e-05 143 524 28 GO:0044036 BP cell wall macromolecule metabolic process sum1 1.12e-06 114 524 26 GO:0048646 BP anatomical structure formation involved in morphogenesis sum1 1.12e-06 114 524 26 GO:0030435 BP sporulation resulting in formation of a cellular spore sum1 9.07e-14 42 524 22 GO:0070590 BP spore wall biogenesis sum1 9.07e-14 42 524 22 GO:0070726 BP cell wall assembly sum1 4.33e-05 247 524 39 GO:0009308 BP amine metabolic process sum1 9.28e-07 106 524 25 GO:0034293 BP sexual sporulation sum1 9.28e-07 106 524 25 GO:0043935 BP sexual sporulation resulting in formation of a cellular spore sum1 9.28e-07 106 524 25 GO:0030437 BP ascospore formation sum1 9.07e-14 42 524 22 GO:0070591 BP ascospore wall biogenesis sum1 2.02e-06 294 524 48 GO:0005975 BP carbohydrate metabolic process sum1 1.1e-05 159 524 30 GO:0005976 BP polysaccharide metabolic process sum1 1.25e-06 129 524 28 GO:0010383 BP cell wall polysaccharide metabolic process sum1 1.25e-06 129 524 28 GO:0006022 BP aminoglycan metabolic process sum1 1.25e-06 129 524 28 GO:0006030 BP chitin metabolic process sum1 8.96e-07 127 524 28 GO:0006037 BP cell wall chitin metabolic process sum1 1.46e-07 117 524 28 GO:0071555 BP cell wall organization sum1 1.46e-07 117 524 28 GO:0007047 BP cellular cell wall organization sum1 9.07e-14 42 524 22 GO:0042244 BP spore wall assembly sum1 9.07e-14 42 524 22 GO:0030476 BP ascospore wall assembly sum1 4e-06 18 524 9 GO:0042763 CC intracellular immature spore sum1 4e-06 18 524 9 GO:0042764 CC ascospore-type prospore sum1 4e-06 18 524 9 GO:0005628 CC prospore membrane sum1 1.83e-06 89 524 22 GO:0030312 CC external encapsulating structure sum1 1.83e-06 89 524 22 GO:0005618 CC cell wall sum1 1.83e-06 89 524 22 GO:0009277 CC fungal-type cell wall sum1 0.00077 10 524 5 REAC:504404 re Nicotinate metabolism sum1 0.00063 3 524 3 REAC:504403 re Tryptophan catabolism sut1 7.31e-08 91 179 15 GO:0016491 MF oxidoreductase activity sut2 1.03e-05 402 175 30 GO:0044429 CC mitochondrial part sut2 1.59e-07 91 175 15 GO:0016491 MF oxidoreductase activity swi6 1.05e-05 89 480 20 GO:0030312 CC external encapsulating structure swi6 1.05e-05 89 480 20 GO:0005618 CC cell wall swi6 1.05e-05 89 480 20 GO:0009277 CC fungal-type cell wall swi6 2.9e-05 23 480 9 GO:0009295 CC nucleoid swi6 2.9e-05 23 480 9 GO:0042645 CC mitochondrial nucleoid swi6 4.09e-06 11 480 7 GO:0000786 CC nucleosome swi6 4.09e-06 11 480 7 GO:0000788 CC nuclear nucleosome swi6 0.000614 23 480 8 KEGG:00260 ke Glycine, serine and threonine metabolism swi6 0.000723 29 480 9 KEGG:00330 ke Arginine and proline metabolism tec1 8.36e-07 22 646 11 GO:0055114 BP oxidation reduction tec1 8.36e-07 22 646 11 GO:0022900 BP electron transport chain tec1 8.36e-07 22 646 11 GO:0022904 BP respiratory electron transport chain tec1 1.04e-06 31 646 13 GO:0006119 BP oxidative phosphorylation tec1 8.36e-07 22 646 11 GO:0042773 BP ATP synthesis coupled electron transport tec1 8.36e-07 22 646 11 GO:0042775 BP mitochondrial ATP synthesis coupled electron transport tec1 7.82e-07 26 646 12 GO:0070469 CC respiratory chain tec1 4.21e-05 225 646 39 GO:0031966 CC mitochondrial membrane tec1 5.2e-05 99 646 22 GO:0044455 CC mitochondrial membrane part tec1 7.82e-07 26 646 12 GO:0005746 CC mitochondrial respiratory chain tec1 6.4e-05 76 646 18 KEGG:00190 ke Oxidative phosphorylation tec1 0.000165 142 646 26 KEGG:03010 ke Ribosome tec1 0.00116 152 646 26 REAC:504522 re 3' -UTR-mediated translational regulation tec1 0.00116 152 646 26 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression tec1 0.000596 259 646 39 REAC:504459 re Gene Expression tec1 0.000276 164 646 29 REAC:504507 re Translation tec1 0.00025 139 646 26 REAC:504506 re Eukaryotic Translation Elongation tec1 0.00025 139 646 26 REAC:504505 re Peptide chain elongation tec1 0.000192 137 646 26 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site tec1 0.000192 137 646 26 REAC:502806 re Hydrolysis of eEF1A:GTP tec1 0.000147 135 646 26 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA tec1 0.00025 139 646 26 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction tec1 0.00015 159 646 29 REAC:504612 re Eukaryotic Translation Initiation tec1 0.00015 159 646 29 REAC:504611 re Cap-dependent Translation Initiation tec1 5.74e-05 136 646 27 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit tec1 5.74e-05 136 646 27 REAC:504077 re The 60S subunit joins the translation initiation complex tec1 5.74e-05 136 646 27 REAC:502286 re eIF5B:GTP is hydrolyzed and released tec1 0.000169 136 646 26 REAC:504765 re Formation of a pool of free 40S subunits tec1 0.000169 136 646 26 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome uga3 2.58e-05 11 213 5 GO:0000786 CC nucleosome uga3 2.58e-05 11 213 5 GO:0000788 CC nuclear nucleosome uga3 0.00139 142 213 15 KEGG:03010 ke Ribosome uga3 0.00016 152 213 18 REAC:504522 re 3' -UTR-mediated translational regulation uga3 0.00016 152 213 18 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression uga3 0.000451 164 213 18 REAC:504507 re Translation uga3 0.000297 159 213 18 REAC:504612 re Eukaryotic Translation Initiation uga3 0.000297 159 213 18 REAC:504611 re Cap-dependent Translation Initiation ume1 4.81e-05 23 406 8 KEGG:04130 ke SNARE interactions in vesicular transport ume1 0.00121 35 406 8 KEGG:03050 ke Proteasome ume1 0.000466 61 406 12 REAC:504578 re Synthesis of DNA ume1 0.000312 3 406 3 REAC:504403 re Tryptophan catabolism ume6 8.29e-05 193 703 38 GO:0034641 BP cellular nitrogen compound metabolic process ume6 1.63e-05 180 703 38 GO:0042180 BP cellular ketone metabolic process ume6 5.57e-05 176 703 36 GO:0006082 BP organic acid metabolic process ume6 5.57e-05 176 703 36 GO:0043436 BP oxoacid metabolic process ume6 5.57e-05 176 703 36 GO:0019752 BP carboxylic acid metabolic process ume6 1.54e-05 38 703 14 GO:0007131 BP reciprocal meiotic recombination ume6 3.1e-05 8 703 6 GO:0042816 BP vitamin B6 metabolic process ume6 3.1e-05 8 703 6 GO:0008614 BP pyridoxine metabolic process ume6 8.47e-05 9 703 6 GO:0042597 CC periplasmic space ume6 8.47e-05 9 703 6 GO:0030287 CC cell wall-bounded periplasmic space ume6 0.00164 9 703 5 KEGG:00460 ke Cyanoamino acid metabolism ume6 0.000187 29 703 11 KEGG:00250 ke Alanine, aspartate and glutamate metabolism ume6 9e-04 29 703 10 KEGG:00330 ke Arginine and proline metabolism ume6 5.3e-05 11 703 7 KEGG:00640 ke Propanoate metabolism ume6 6.04e-05 616 703 95 KEGG:01100 ke Metabolic pathways ume6 0.000293 11 703 6 REAC:504513 re Ornithine and proline metabolism ume6 0.000437 8 703 5 REAC:504512 re Ornithine metabolism upc2 1e-04 24 74 4 GO:0008202 BP steroid metabolic process upc2 0.000612 15 74 3 KEGG:00100 ke Steroid biosynthesis upc2 0.000391 13 74 3 KEGG:00740 ke Riboflavin metabolism upc2 0.000421 6 74 2 REAC:504406 re Transformation of lanosterol to cholesterol wtm2 7.38e-05 4 169 3 GO:0005946 CC alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) wtm2 1.5e-06 40 169 9 KEGG:00500 ke Starch and sucrose metabolism wtm2 1.54e-05 8 169 4 REAC:504500 re Glycogen synthesis xbp1 0.00106 13 104 3 KEGG:00300 ke Lysine biosynthesis yap5 6.98e-09 142 145 18 KEGG:03010 ke Ribosome yap5 8.38e-06 200 145 18 REAC:504343 re Metabolism of proteins yap5 1.87e-05 259 145 20 REAC:504459 re Gene Expression yap5 2.4e-06 164 145 17 REAC:504507 re Translation yap5 1.84e-07 139 145 17 REAC:504506 re Eukaryotic Translation Elongation yap5 1.84e-07 139 145 17 REAC:504505 re Peptide chain elongation yap5 1.46e-07 137 145 17 REAC:502806 re Hydrolysis of eEF1A:GTP yap5 1.46e-07 137 145 17 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site yap5 1.16e-07 135 145 17 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA yap5 1.84e-07 139 145 17 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction yap5 1.49e-06 159 145 17 REAC:504612 re Eukaryotic Translation Initiation yap5 1.49e-06 159 145 17 REAC:504611 re Cap-dependent Translation Initiation yap5 1.3e-07 136 145 17 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit yap5 1.3e-07 136 145 17 REAC:504077 re The 60S subunit joins the translation initiation complex yap5 1.3e-07 136 145 17 REAC:502286 re eIF5B:GTP is hydrolyzed and released yap5 1.3e-07 136 145 17 REAC:504765 re Formation of a pool of free 40S subunits yap5 1.3e-07 136 145 17 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome yap5 7.47e-07 152 145 17 REAC:504522 re 3' -UTR-mediated translational regulation yap5 7.47e-07 152 145 17 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression yap5 0.00014 79 145 10 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit ybl054w 5.57e-05 6 83 3 GO:0016638 MF oxidoreductase activity, acting on the CH-NH2 group of donors ybl054w 1.14e-05 4 83 3 GO:0016642 MF oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor ybl054w 1.14e-05 4 83 3 GO:0004375 MF glycine dehydrogenase (decarboxylating) activity ybr033w 4.27e-06 180 132 15 GO:0042180 BP cellular ketone metabolic process ybr033w 3.22e-06 176 132 15 GO:0006082 BP organic acid metabolic process ybr033w 3.22e-06 176 132 15 GO:0043436 BP oxoacid metabolic process ybr033w 3.22e-06 176 132 15 GO:0019752 BP carboxylic acid metabolic process ybr033w 1.62e-05 55 132 8 GO:0009309 BP amine biosynthetic process ybr033w 4.46e-05 193 132 14 GO:0034641 BP cellular nitrogen compound metabolic process ybr033w 3.48e-06 113 132 12 GO:0044106 BP cellular amine metabolic process ybr033w 7.05e-06 65 132 9 GO:0016053 BP organic acid biosynthetic process ybr033w 7.05e-06 65 132 9 GO:0046394 BP carboxylic acid biosynthetic process ybr033w 1e-05 125 132 12 GO:0006519 BP cellular amino acid and derivative metabolic process ybr033w 7.44e-07 98 132 12 GO:0006520 BP cellular amino acid metabolic process ybr033w 3.68e-05 31 132 6 GO:0009066 BP aspartate family amino acid metabolic process ybr033w 2.03e-07 8 132 5 GO:0006553 BP lysine metabolic process ybr033w 7.77e-06 50 132 8 GO:0008652 BP cellular amino acid biosynthetic process ybr033w 6.56e-06 14 132 5 GO:0009067 BP aspartate family amino acid biosynthetic process ybr033w 2.03e-07 8 132 5 GO:0009085 BP lysine biosynthetic process ybr033w 2.03e-07 8 132 5 GO:0019878 BP lysine biosynthetic process via aminoadipic acid ybr033w 0.00152 29 132 5 KEGG:00250 ke Alanine, aspartate and glutamate metabolism ybr033w 8.96e-07 13 132 6 KEGG:00300 ke Lysine biosynthesis ybr033w 0.00075 616 132 30 KEGG:01100 ke Metabolic pathways ybr033w 0.000439 6 132 3 REAC:504411 re De novo synthesis of IMP ybr239c 0.00175 14 200 4 KEGG:00670 ke One carbon pool by folate ydr026c 0.000934 29 88 4 KEGG:00330 ke Arginine and proline metabolism ydr049w 0.000538 125 185 13 KEGG:04111 ke Cell cycle - yeast ydr266c 3.63e-05 60 205 10 GO:0055066 BP di-, tri-valent inorganic cation homeostasis ydr266c 2.06e-05 35 205 8 GO:0055072 BP iron ion homeostasis ydr266c 3.63e-05 60 205 10 GO:0030005 BP cellular di-, tri-valent inorganic cation homeostasis ydr266c 2.06e-05 35 205 8 GO:0006879 BP cellular iron ion homeostasis ydr266c 4.56e-08 8 205 6 GO:0033212 BP iron assimilation ydr266c 2.95e-07 6 205 5 GO:0033214 BP iron assimilation by chelation and transport ydr266c 1.99e-09 9 205 7 GO:0015891 BP siderophore transport ydr266c 5.5e-08 24 205 9 GO:0015674 BP di-, tri-valent inorganic cation transport ydr266c 1.16e-05 53 205 10 GO:0030001 BP metal ion transport ydr266c 1.23e-06 42 205 10 GO:0000041 BP transition metal ion transport ydr266c 2e-08 16 205 8 GO:0006826 BP iron ion transport ydr266c 2.95e-07 6 205 5 GO:0015688 BP iron chelate transport ydr266c 2.95e-07 6 205 5 GO:0015892 BP siderophore-iron transport ydr266c 3.82e-05 86 205 12 GO:0006811 BP ion transport ydr266c 1.96e-05 11 205 5 GO:0000307 CC cyclin-dependent protein kinase holoenzyme complex ydr266c 3.7e-05 28 205 7 GO:0046915 MF transition metal ion transmembrane transporter activity ydr266c 1.34e-06 12 205 6 GO:0005381 MF iron ion transmembrane transporter activity ydr266c 0.00101 14 205 4 KEGG:00670 ke One carbon pool by folate ydr520c 0.000413 67 299 10 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex ydr520c 0.000413 67 299 10 REAC:502531 re Formation of the 43S pre-initiation complex yer028c 0.000763 18 162 4 KEGG:00290 ke Valine, leucine and isoleucine biosynthesis yfl044c 0.000459 23 242 6 KEGG:04130 ke SNARE interactions in vesicular transport ygl131c 0.000244 8 106 3 REAC:504512 re Ornithine metabolism ygl131c 0.000297 2 106 2 REAC:503313 re ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde ygl131c 0.000297 2 106 2 REAC:502634 re glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate ygr067c 2.84e-05 7 182 4 GO:0005885 CC Arp2/3 protein complex ygr067c 2.84e-05 7 182 4 GO:0019773 CC proteasome core complex, alpha-subunit complex ygr067c 5e-05 35 182 7 KEGG:03050 ke Proteasome ygr067c 0.000388 67 182 8 REAC:504556 re S Phase ygr067c 0.000197 61 182 8 REAC:504578 re Synthesis of DNA ygr067c 0.000461 37 182 6 REAC:504756 re Regulation of Apoptosis ygr067c 0.000461 37 182 6 REAC:504755 re Regulation of activated PAK-2p34 by proteasome mediated degradation ygr067c 0.000461 37 182 6 REAC:503734 re Proteasome mediated degradation of PAK-2p34 ygr067c 0.000349 66 182 8 REAC:504575 re DNA Replication ygr067c 0.000394 36 182 6 REAC:504576 re CDK-mediated phosphorylation and removal of Cdc6 ygr067c 0.000335 35 182 6 REAC:504199 re Ubiquitinated Cdc6 is degraded by the proteasome ygr067c 0.000335 35 182 6 REAC:504738 re Orc1 removal from chromatin ygr067c 0.000335 35 182 6 REAC:504203 re Ubiquitinated Orc1 is degraded by the proteasome ygr067c 0.000335 35 182 6 REAC:504744 re G1/S DNA Damage Checkpoints ygr067c 0.000335 35 182 6 REAC:504743 re p53-Independent G1/S DNA damage checkpoint ygr067c 0.000335 35 182 6 REAC:504742 re p53-Independent DNA Damage Response ygr067c 0.000335 35 182 6 REAC:504757 re Ubiquitin Mediated Degradation of Phosphorylated Cdc25A ygr067c 0.000335 35 182 6 REAC:503737 re Proteolytic degradation of ubiquitinated-Cdc25A ygr089w 2.12e-05 5 299 4 GO:0043562 BP cellular response to nitrogen levels ygr089w 2.12e-05 5 299 4 GO:0006995 BP cellular response to nitrogen starvation ygr089w 7.89e-05 889 299 64 GO:0051179 BP localization ygr089w 2.64e-05 841 299 63 GO:0051234 BP establishment of localization ygr089w 1.53e-05 827 299 63 GO:0006810 BP transport ygr089w 3.07e-05 86 299 14 GO:0006811 BP ion transport ygr089w 7.84e-05 71 299 12 GO:0006812 BP cation transport ygr089w 4.04e-06 63 299 13 GO:0070085 BP glycosylation ygr089w 4.04e-06 63 299 13 GO:0043413 BP macromolecule glycosylation ygr089w 1.16e-05 69 299 13 GO:0009100 BP glycoprotein metabolic process ygr089w 3.42e-06 11 299 6 GO:0009312 BP oligosaccharide biosynthetic process ygr089w 9.85e-06 68 299 13 GO:0009101 BP glycoprotein biosynthetic process ygr089w 4.04e-06 63 299 13 GO:0006486 BP protein amino acid glycosylation ygr089w 5.12e-07 45 299 12 GO:0006487 BP protein amino acid N-linked glycosylation ygr089w 3.42e-06 11 299 6 GO:0006488 BP dolichol-linked oligosaccharide biosynthetic process ygr089w 2.18e-08 154 299 25 GO:0006629 BP lipid metabolic process ygr089w 5.19e-07 122 299 20 GO:0044255 BP cellular lipid metabolic process ygr089w 3.72e-07 23 299 9 GO:0006643 BP membrane lipid metabolic process ygr089w 3.72e-07 23 299 9 GO:0006665 BP sphingolipid metabolic process ygr089w 3.6e-06 72 299 14 GO:0008610 BP lipid biosynthetic process ygr089w 1.26e-05 19 299 7 GO:0046467 BP membrane lipid biosynthetic process ygr089w 1.26e-05 19 299 7 GO:0030148 BP sphingolipid biosynthetic process ygr089w 6.13e-05 6 299 4 GO:0006633 BP fatty acid biosynthetic process ygr089w 4.4e-06 4 299 4 GO:0030497 BP fatty acid elongation ygr089w 5.07e-06 117 299 18 GO:0048878 BP chemical homeostasis ygr089w 5.07e-06 117 299 18 GO:0050801 BP ion homeostasis ygr089w 7.47e-07 103 299 18 GO:0055080 BP cation homeostasis ygr089w 2.25e-06 60 299 13 GO:0055066 BP di-, tri-valent inorganic cation homeostasis ygr089w 4.15e-05 10 299 5 GO:0055069 BP zinc ion homeostasis ygr089w 3.46e-06 114 299 18 GO:0019725 BP cellular homeostasis ygr089w 3.04e-06 113 299 18 GO:0055082 BP cellular chemical homeostasis ygr089w 3.04e-06 113 299 18 GO:0006873 BP cellular ion homeostasis ygr089w 4.04e-07 99 299 18 GO:0030003 BP cellular cation homeostasis ygr089w 2.25e-06 60 299 13 GO:0030005 BP cellular di-, tri-valent inorganic cation homeostasis ygr089w 4.15e-05 10 299 5 GO:0006882 BP cellular zinc ion homeostasis ygr089w 1.42e-05 42 299 10 GO:0000041 BP transition metal ion transport ygr089w 8.65e-16 790 299 85 GO:0016020 CC membrane ygr089w 3.72e-07 394 299 41 GO:0044425 CC membrane part ygr089w 3.46e-11 533 299 59 GO:0031090 CC organelle membrane ygr089w 8.34e-07 210 299 27 GO:0005886 CC plasma membrane ygr089w 5.86e-05 69 299 12 GO:0031300 CC intrinsic to organelle membrane ygr089w 4.33e-05 67 299 12 GO:0031301 CC integral to organelle membrane ygr089w 5.12e-10 252 299 36 GO:0012505 CC endomembrane system ygr089w 9.34e-10 133 299 25 GO:0042175 CC nuclear envelope-endoplasmic reticulum network ygr089w 3.17e-05 15 299 6 GO:0031228 CC intrinsic to Golgi membrane ygr089w 3.17e-05 15 299 6 GO:0030173 CC integral to Golgi membrane ygr089w 7.33e-05 2335 299 136 GO:0005737 CC cytoplasm ygr089w 1.77e-09 1796 299 126 GO:0044444 CC cytoplasmic part ygr089w 1.53e-09 136 299 25 GO:0071212 CC subsynaptic reticulum ygr089w 1.56e-19 198 299 44 GO:0005773 CC vacuole ygr089w 1.42e-17 164 299 38 GO:0000323 CC lytic vacuole ygr089w 1.42e-17 164 299 38 GO:0000322 CC storage vacuole ygr089w 1.42e-17 164 299 38 GO:0000324 CC fungal-type vacuole ygr089w 5.15e-12 115 299 26 GO:0044437 CC vacuolar part ygr089w 5.31e-11 108 299 24 GO:0005774 CC vacuolar membrane ygr089w 1.18e-08 71 299 17 GO:0000329 CC fungal-type vacuole membrane ygr089w 8.77e-14 221 299 39 GO:0005783 CC endoplasmic reticulum ygr089w 1.53e-09 136 299 25 GO:0044432 CC endoplasmic reticulum part ygr089w 4.33e-09 122 299 23 GO:0005789 CC endoplasmic reticulum membrane ygr089w 2.16e-05 9 299 5 GO:0042597 CC periplasmic space ygr089w 2.16e-05 9 299 5 GO:0030287 CC cell wall-bounded periplasmic space ygr089w 1.42e-05 42 299 10 GO:0016746 MF transferase activity, transferring acyl groups ygr089w 1.06e-08 268 299 35 GO:0005215 MF transporter activity ygr089w 3.23e-09 244 299 34 GO:0022892 MF substrate-specific transporter activity ygr089w 1.65e-09 214 299 32 GO:0022857 MF transmembrane transporter activity ygr089w 3.76e-10 191 299 31 GO:0022891 MF substrate-specific transmembrane transporter activity ygr089w 7.67e-08 99 299 19 GO:0015075 MF ion transmembrane transporter activity ygr089w 1.32e-06 86 299 16 GO:0008324 MF cation transmembrane transporter activity ygr089w 2.24e-07 76 299 16 GO:0022890 MF inorganic cation transmembrane transporter activity ygr089w 7.61e-10 33 299 13 GO:0015082 MF di-, tri-valent inorganic cation transmembrane transporter activity ygr089w 4.01e-09 37 299 13 GO:0046873 MF metal ion transmembrane transporter activity ygr089w 1.09e-09 28 299 12 GO:0046915 MF transition metal ion transmembrane transporter activity ygr089w 6.13e-05 6 299 4 GO:0005385 MF zinc ion transmembrane transporter activity ygr089w 1.64e-08 29 299 11 KEGG:00510 ke N-Glycan biosynthesis ygr089w 0.000442 9 299 4 KEGG:00460 ke Cyanoamino acid metabolism ygr089w 1.43e-06 10 299 6 KEGG:01040 ke Biosynthesis of unsaturated fatty acids yil130w 1.77e-05 5 258 4 GO:0006110 BP regulation of glycolysis yil130w 5.67e-07 328 258 35 GO:0022613 BP ribonucleoprotein complex biogenesis yil130w 1.01e-07 306 258 35 GO:0042254 BP ribosome biogenesis yil130w 9.4e-05 26 258 7 GO:0070469 CC respiratory chain yil130w 9.4e-05 26 258 7 GO:0005746 CC mitochondrial respiratory chain yil130w 0.00202 7 258 3 KEGG:00760 ke Nicotinate and nicotinamide metabolism yil130w 0.000704 76 258 10 KEGG:00190 ke Oxidative phosphorylation ykl005c 2.95e-07 8 129 5 GO:0033212 BP iron assimilation ykl005c 3.67e-06 6 129 4 GO:0033214 BP iron assimilation by chelation and transport ykl005c 2.93e-05 9 129 4 GO:0015891 BP siderophore transport ykl005c 1.99e-05 16 129 5 GO:0006826 BP iron ion transport ykl005c 3.67e-06 6 129 4 GO:0015688 BP iron chelate transport ykl005c 3.67e-06 6 129 4 GO:0015892 BP siderophore-iron transport ykl005c 5.32e-05 60 129 8 GO:0055066 BP di-, tri-valent inorganic cation homeostasis ykl005c 5.32e-05 60 129 8 GO:0030005 BP cellular di-, tri-valent inorganic cation homeostasis ykl005c 1.25e-06 5 129 4 GO:0043562 BP cellular response to nitrogen levels ykl005c 1.25e-06 5 129 4 GO:0006995 BP cellular response to nitrogen starvation ykl005c 2.93e-05 9 129 4 GO:0042597 CC periplasmic space ykl005c 2.93e-05 9 129 4 GO:0030287 CC cell wall-bounded periplasmic space ykl005c 4.51e-05 4 129 3 GO:0016642 MF oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor ykl005c 4.51e-05 4 129 3 GO:0004375 MF glycine dehydrogenase (decarboxylating) activity ykl005c 4.11e-05 9 129 4 KEGG:00460 ke Cyanoamino acid metabolism ykl005c 0.00062 29 129 5 KEGG:00250 ke Alanine, aspartate and glutamate metabolism ykl005c 4.04e-05 17 129 5 KEGG:00910 ke Nitrogen metabolism ykl222c 1.06e-05 32 58 5 GO:0006312 BP mitotic recombination ykl222c 8.87e-07 20 58 5 GO:0000722 BP telomere maintenance via recombination ykl222c 1.06e-05 32 58 5 GO:0003678 MF DNA helicase activity ykr064w 3.69e-06 91 118 11 GO:0016491 MF oxidoreductase activity ykr064w 4.04e-05 4 118 3 GO:0016642 MF oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor ykr064w 4.04e-05 4 118 3 GO:0004375 MF glycine dehydrogenase (decarboxylating) activity ykr064w 0.00172 125 118 10 KEGG:04111 ke Cell cycle - yeast ykr064w 0.000327 99 118 6 REAC:504439 re Cell Cycle, Mitotic ylr278c 7.5e-07 625 424 79 GO:0010467 BP gene expression ylr278c 4.99e-07 619 424 79 GO:0044085 BP cellular component biogenesis ylr278c 1.18e-08 328 424 54 GO:0022613 BP ribonucleoprotein complex biogenesis ylr278c 2.59e-09 306 424 53 GO:0042254 BP ribosome biogenesis ylr278c 3.26e-10 558 424 82 GO:0016070 BP cellular RNA metabolic process ylr278c 4.13e-11 203 424 44 GO:0034660 BP ncRNA metabolic process ylr278c 1.64e-12 124 424 35 GO:0016072 BP rRNA metabolic process ylr278c 1.24e-06 337 424 50 GO:0006396 BP RNA processing ylr278c 8.7e-10 190 424 40 GO:0034470 BP ncRNA processing ylr278c 2.38e-11 115 424 32 GO:0006364 BP rRNA processing ylr278c 2.13e-05 34 424 11 GO:0000460 BP maturation of 5.8S rRNA ylr278c 1.1e-05 32 424 11 GO:0000466 BP maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ylr278c 8.76e-06 43 424 13 GO:0030490 BP maturation of SSU-rRNA ylr278c 8.76e-06 43 424 13 GO:0000462 BP maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ylr278c 5.48e-05 631 424 73 GO:0031974 CC membrane-enclosed lumen ylr278c 5.79e-05 801 424 88 GO:0043228 CC non-membrane-bounded organelle ylr278c 5.79e-05 801 424 88 GO:0043232 CC intracellular non-membrane-bounded organelle ylr278c 8.21e-06 598 424 73 GO:0043233 CC organelle lumen ylr278c 8.21e-06 598 424 73 GO:0070013 CC intracellular organelle lumen ylr278c 5.07e-06 1169 424 124 GO:0005634 CC nucleus ylr278c 5.18e-06 833 424 95 GO:0044428 CC nuclear part ylr278c 2.78e-07 427 424 61 GO:0031981 CC nuclear lumen ylr278c 1.24e-09 208 424 42 GO:0005730 CC nucleolus ylr278c 4.26e-05 7 424 5 GO:0019773 CC proteasome core complex, alpha-subunit complex ylr278c 0.000893 35 424 9 KEGG:03050 ke Proteasome ylr278c 0.000452 35 424 8 REAC:504738 re Orc1 removal from chromatin ylr278c 0.000452 35 424 8 REAC:504203 re Ubiquitinated Orc1 is degraded by the proteasome ylr278c 0.000556 36 424 8 REAC:504576 re CDK-mediated phosphorylation and removal of Cdc6 ylr278c 0.000452 35 424 8 REAC:504199 re Ubiquitinated Cdc6 is degraded by the proteasome ylr278c 0.000452 35 424 8 REAC:504744 re G1/S DNA Damage Checkpoints ylr278c 0.000452 35 424 8 REAC:504743 re p53-Independent G1/S DNA damage checkpoint ylr278c 0.000452 35 424 8 REAC:504742 re p53-Independent DNA Damage Response ylr278c 0.000452 35 424 8 REAC:504757 re Ubiquitin Mediated Degradation of Phosphorylated Cdc25A ylr278c 0.000452 35 424 8 REAC:503737 re Proteolytic degradation of ubiquitinated-Cdc25A ylr278c 0.000679 37 424 8 REAC:504756 re Regulation of Apoptosis ylr278c 0.000679 37 424 8 REAC:504755 re Regulation of activated PAK-2p34 by proteasome mediated degradation ylr278c 0.000679 37 424 8 REAC:503734 re Proteasome mediated degradation of PAK-2p34 yml081w 1.37e-05 42 216 9 GO:0000041 BP transition metal ion transport yml081w 2.54e-05 35 216 8 GO:0055072 BP iron ion homeostasis yml081w 1.57e-07 9 216 6 GO:0015891 BP siderophore transport yml081w 1.47e-05 24 216 7 GO:0015674 BP di-, tri-valent inorganic cation transport yml081w 1.21e-05 16 216 6 GO:0006826 BP iron ion transport yml081w 2.34e-05 6 216 4 GO:0015688 BP iron chelate transport yml081w 2.54e-05 35 216 8 GO:0006879 BP cellular iron ion homeostasis yml081w 2.99e-06 8 216 5 GO:0033212 BP iron assimilation yml081w 2.34e-05 6 216 4 GO:0033214 BP iron assimilation by chelation and transport yml081w 2.34e-05 6 216 4 GO:0015892 BP siderophore-iron transport yml081w 8.02e-06 5 216 4 GO:0009051 BP pentose-phosphate shunt, oxidative branch yml081w 1.47e-05 24 216 7 GO:0008202 BP steroid metabolic process yml081w 2.99e-06 8 216 5 GO:0016128 BP phytosteroid metabolic process yml081w 2.99e-06 8 216 5 GO:0008204 BP ergosterol metabolic process yml081w 4.46e-05 72 216 11 GO:0008610 BP lipid biosynthetic process yml081w 4.84e-06 14 216 6 GO:0006694 BP steroid biosynthetic process yml081w 2.99e-06 8 216 5 GO:0016129 BP phytosteroid biosynthetic process yml081w 4.84e-06 14 216 6 GO:0016126 BP sterol biosynthetic process yml081w 2.99e-06 8 216 5 GO:0006696 BP ergosterol biosynthetic process yml081w 7.6e-08 89 216 16 GO:0030312 CC external encapsulating structure yml081w 7.6e-08 89 216 16 GO:0005618 CC cell wall yml081w 7.6e-08 89 216 16 GO:0009277 CC fungal-type cell wall yml081w 4.45e-05 28 216 7 GO:0046915 MF transition metal ion transmembrane transporter activity yml081w 3.76e-05 12 216 5 GO:0005381 MF iron ion transmembrane transporter activity yml081w 1.88e-05 91 216 13 GO:0016491 MF oxidoreductase activity yml081w 3.62e-05 15 216 6 KEGG:00100 ke Steroid biosynthesis yml081w 0.000133 12 216 5 REAC:504417 re Pentose phosphate pathway (hexose monophosphate shunt) yml081w 6.83e-05 6 216 4 REAC:504406 re Transformation of lanosterol to cholesterol ymr075w 0.000967 15 465 6 KEGG:00340 ke Histidine metabolism ymr075w 0.000624 14 465 6 KEGG:00670 ke One carbon pool by folate ymr075w 1.6e-05 8 465 6 REAC:504416 re Synaptic Transmission ymr075w 1.6e-05 8 465 6 REAC:504415 re Transmission across Chemical Synapses ymr075w 8.04e-05 4 465 4 REAC:503910 re Release of Peptidyl-prolyl cis-trans isomerase A ynr063w 0.00207 9 54 2 KEGG:00460 ke Cyanoamino acid metabolism ynr063w 0.00129 29 54 3 KEGG:00250 ke Alanine, aspartate and glutamate metabolism yox1 0.00204 125 158 9 KEGG:04111 ke Cell cycle - yeast ypr022c 2.91e-05 89 122 9 GO:0030312 CC external encapsulating structure ypr022c 2.91e-05 89 122 9 GO:0005618 CC cell wall ypr022c 2.91e-05 89 122 9 GO:0009277 CC fungal-type cell wall ypr196w 0.00134 40 163 6 KEGG:00500 ke Starch and sucrose metabolism ypr196w 0.00141 125 163 11 KEGG:04111 ke Cell cycle - yeast yrr1 2.23e-05 99 152 10 REAC:504439 re Cell Cycle, Mitotic yrr1 6.27e-05 67 152 8 REAC:504556 re S Phase yrr1 3.07e-05 61 152 8 REAC:504578 re Synthesis of DNA yrr1 0.000201 14 152 4 REAC:504669 re Lagging Strand Synthesis yrr1 5.59e-05 66 152 8 REAC:504575 re DNA Replication zap1 0.00171 11 123 3 KEGG:00770 ke Pantothenate and CoA biosynthesis zap1 0.000378 16 123 4 KEGG:00380 ke Tryptophan metabolism zap1 0.000418 29 123 5 KEGG:00330 ke Arginine and proline metabolism zap1 0.000614 18 123 4 KEGG:00290 ke Valine, leucine and isoleucine biosynthesis zap1 0.000611 8 123 3 KEGG:00410 ke beta-Alanine metabolism zap1 0.00127 10 123 3 KEGG:00280 ke Valine, leucine and isoleucine degradation zap1 0.000218 49 123 6 REAC:504363 re Metabolism of amino acids zms1 0.000293 13 142 4 KEGG:00740 ke Riboflavin metabolism zms1 0.00034 2 142 2 REAC:502078 re Dephosphorylation of nuclear Cyclin A:phosph-Cdc2 complexes zms1 0.00034 2 142 2 REAC:501604 re Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 cst6 7.89e-06 456 2482 228 GO:0044281 BP small molecule metabolic process cst6 1.95e-09 328 2482 184 GO:0022613 BP ribonucleoprotein complex biogenesis cst6 1.46e-10 306 2482 177 GO:0042254 BP ribosome biogenesis cst6 1.95e-07 208 2482 120 GO:0005730 CC nucleolus cst6 3.76e-27 142 2482 128 KEGG:03010 ke Ribosome cst6 1.34e-22 152 2482 135 REAC:504522 re 3' -UTR-mediated translational regulation cst6 1.34e-22 152 2482 135 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression cst6 1.14e-17 79 2482 76 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit cst6 4.19e-07 76 2482 62 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA cst6 2.62e-20 200 2482 165 REAC:504343 re Metabolism of proteins cst6 1.74e-12 259 2482 189 REAC:504459 re Gene Expression cst6 2.42e-21 164 2482 142 REAC:504507 re Translation cst6 5.52e-21 139 2482 124 REAC:504506 re Eukaryotic Translation Elongation cst6 5.52e-21 139 2482 124 REAC:504505 re Peptide chain elongation cst6 2.12e-21 137 2482 123 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site cst6 2.12e-21 137 2482 123 REAC:502806 re Hydrolysis of eEF1A:GTP cst6 7.28e-21 135 2482 121 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA cst6 5.52e-21 139 2482 124 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction cst6 9.36e-22 159 2482 139 REAC:504612 re Eukaryotic Translation Initiation cst6 9.36e-22 159 2482 139 REAC:504611 re Cap-dependent Translation Initiation cst6 1.01e-06 74 2482 60 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S cst6 1.01e-06 74 2482 60 REAC:504671 re Translation initiation complex formation cst6 1.57e-06 73 2482 59 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize cst6 1.01e-06 74 2482 60 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation cst6 1.01e-06 74 2482 60 REAC:504769 re Ribosomal scanning and start codon recognition cst6 1.57e-06 73 2482 59 REAC:503952 re Ribosomal scanning cst6 1.01e-06 74 2482 60 REAC:504040 re Start codon recognition cst6 5.55e-06 67 2482 54 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex cst6 5.55e-06 67 2482 54 REAC:502531 re Formation of the 43S pre-initiation complex cst6 3.42e-20 136 2482 121 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit cst6 3.42e-20 136 2482 121 REAC:504077 re The 60S subunit joins the translation initiation complex cst6 3.42e-20 136 2482 121 REAC:502286 re eIF5B:GTP is hydrolyzed and released cst6 3.42e-20 136 2482 121 REAC:504765 re Formation of a pool of free 40S subunits cst6 3.42e-20 136 2482 121 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome flo8 3.59e-05 198 245 21 GO:0005773 CC vacuole flo8 0.000134 40 245 8 KEGG:00500 ke Starch and sucrose metabolism flo8 0.00014 8 245 4 REAC:504500 re Glycogen synthesis gat3 2.36e-05 625 168 36 GO:0010467 BP gene expression gat3 3.05e-10 619 168 46 GO:0044085 BP cellular component biogenesis gat3 2.35e-18 328 168 43 GO:0022613 BP ribonucleoprotein complex biogenesis gat3 1.12e-18 306 168 42 GO:0042254 BP ribosome biogenesis gat3 1.07e-07 61 168 12 GO:0042273 BP ribosomal large subunit biogenesis gat3 1.95e-07 558 168 38 GO:0016070 BP cellular RNA metabolic process gat3 1.57e-12 203 168 28 GO:0034660 BP ncRNA metabolic process gat3 2.51e-11 124 168 21 GO:0016072 BP rRNA metabolic process gat3 7.62e-07 337 168 27 GO:0006396 BP RNA processing gat3 8.37e-11 190 168 25 GO:0034470 BP ncRNA processing gat3 3.79e-10 115 168 19 GO:0006364 BP rRNA processing gat3 4.52e-05 60 168 9 GO:0042255 BP ribosome assembly gat3 8.75e-05 51 168 8 GO:0042257 BP ribosomal subunit assembly gat3 9.22e-06 38 168 8 GO:0000027 BP ribosomal large subunit assembly gat3 1.65e-10 631 168 47 GO:0031974 CC membrane-enclosed lumen gat3 1.21e-09 598 168 44 GO:0043233 CC organelle lumen gat3 1.21e-09 598 168 44 GO:0070013 CC intracellular organelle lumen gat3 2.31e-07 1169 168 61 GO:0005634 CC nucleus gat3 5.2e-07 833 168 48 GO:0044428 CC nuclear part gat3 1.13e-12 427 168 41 GO:0031981 CC nuclear lumen gat3 1.49e-16 208 168 33 GO:0005730 CC nucleolus gat3 4e-05 34 168 7 GO:0003724 MF RNA helicase activity gat3 7.83e-06 27 168 7 GO:0008186 MF RNA-dependent ATPase activity gat3 7.83e-06 27 168 7 GO:0004004 MF ATP-dependent RNA helicase activity gts1 2.65e-22 142 423 50 KEGG:03010 ke Ribosome gts1 1.3e-10 200 423 51 REAC:504343 re Metabolism of proteins gts1 4.3e-07 259 423 53 REAC:504459 re Gene Expression gts1 2.18e-12 164 423 48 REAC:504507 re Translation gts1 1.03e-15 139 423 48 REAC:504506 re Eukaryotic Translation Elongation gts1 1.03e-15 139 423 48 REAC:504505 re Peptide chain elongation gts1 5.1e-16 137 423 48 REAC:502806 re Hydrolysis of eEF1A:GTP gts1 5.1e-16 137 423 48 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site gts1 2.48e-16 135 423 48 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA gts1 1.03e-15 139 423 48 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction gts1 5.49e-13 159 423 48 REAC:504612 re Eukaryotic Translation Initiation gts1 5.49e-13 159 423 48 REAC:504611 re Cap-dependent Translation Initiation gts1 3.57e-16 136 423 48 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit gts1 3.57e-16 136 423 48 REAC:504077 re The 60S subunit joins the translation initiation complex gts1 3.57e-16 136 423 48 REAC:502286 re eIF5B:GTP is hydrolyzed and released gts1 3.57e-16 136 423 48 REAC:504765 re Formation of a pool of free 40S subunits gts1 3.57e-16 136 423 48 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome gts1 7.07e-14 152 423 48 REAC:504522 re 3' -UTR-mediated translational regulation gts1 7.07e-14 152 423 48 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression gts1 3.71e-13 79 423 33 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit hfi1 4.13e-07 131 1439 55 GO:0044283 BP small molecule biosynthetic process hfi1 1.45e-09 89 1439 46 GO:0030312 CC external encapsulating structure hfi1 1.45e-09 89 1439 46 GO:0005618 CC cell wall hfi1 1.45e-09 89 1439 46 GO:0009277 CC fungal-type cell wall hfi1 1.12e-44 142 1439 119 KEGG:03010 ke Ribosome hfi1 4.94e-26 200 1439 130 REAC:504343 re Metabolism of proteins hfi1 3.72e-16 259 1439 139 REAC:504459 re Gene Expression hfi1 1.39e-30 164 1439 119 REAC:504507 re Translation hfi1 1.33e-39 139 1439 115 REAC:504506 re Eukaryotic Translation Elongation hfi1 1.33e-39 139 1439 115 REAC:504505 re Peptide chain elongation hfi1 6.52e-41 137 1439 115 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site hfi1 6.52e-41 137 1439 115 REAC:502806 re Hydrolysis of eEF1A:GTP hfi1 4.87e-41 135 1439 114 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA hfi1 1.33e-39 139 1439 115 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction hfi1 6.55e-32 159 1439 118 REAC:504612 re Eukaryotic Translation Initiation hfi1 6.55e-32 159 1439 118 REAC:504611 re Cap-dependent Translation Initiation hfi1 1.2e-07 74 1439 46 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S hfi1 1.2e-07 74 1439 46 REAC:504671 re Translation initiation complex formation hfi1 2.45e-07 73 1439 45 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize hfi1 1.2e-07 74 1439 46 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation hfi1 1.2e-07 74 1439 46 REAC:504769 re Ribosomal scanning and start codon recognition hfi1 2.45e-07 73 1439 45 REAC:503952 re Ribosomal scanning hfi1 1.2e-07 74 1439 46 REAC:504040 re Start codon recognition hfi1 4.53e-09 67 1439 45 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex hfi1 4.53e-09 67 1439 45 REAC:502531 re Formation of the 43S pre-initiation complex hfi1 2.3e-40 136 1439 114 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit hfi1 2.3e-40 136 1439 114 REAC:504077 re The 60S subunit joins the translation initiation complex hfi1 2.3e-40 136 1439 114 REAC:502286 re eIF5B:GTP is hydrolyzed and released hfi1 2.3e-40 136 1439 114 REAC:504765 re Formation of a pool of free 40S subunits hfi1 2.3e-40 136 1439 114 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome hfi1 2.36e-34 152 1439 117 REAC:504522 re 3' -UTR-mediated translational regulation hfi1 2.36e-34 152 1439 117 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression hfi1 5.64e-28 79 1439 71 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit hfi1 2.82e-08 76 1439 48 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA mac1 0.000889 76 273 11 KEGG:00190 ke Oxidative phosphorylation sin4 6.21e-06 89 2222 53 GO:0030312 CC external encapsulating structure sin4 6.21e-06 89 2222 53 GO:0005618 CC cell wall sin4 6.21e-06 89 2222 53 GO:0009277 CC fungal-type cell wall sin4 7.94e-06 47 2222 34 KEGG:00010 ke Glycolysis / Gluconeogenesis snf2 2.56e-06 18 2069 16 GO:0006090 BP pyruvate metabolic process snf2 1.06e-06 190 2069 97 GO:0034470 BP ncRNA processing snf2 1.62e-07 203 2069 105 GO:0034660 BP ncRNA metabolic process snf2 2.88e-07 124 2069 70 GO:0016072 BP rRNA metabolic process snf2 8.19e-08 619 2069 272 GO:0044085 BP cellular component biogenesis snf2 9.1e-06 70 2069 42 GO:0070925 BP organelle assembly snf2 1.1e-15 328 2069 181 GO:0022613 BP ribonucleoprotein complex biogenesis snf2 1.07e-17 306 2069 176 GO:0042254 BP ribosome biogenesis snf2 1.11e-06 60 2069 39 GO:0042255 BP ribosome assembly snf2 2.31e-06 51 2069 34 GO:0042257 BP ribosomal subunit assembly snf2 7.25e-07 115 2069 65 GO:0006364 BP rRNA processing snf2 5.69e-07 61 2069 40 GO:0042273 BP ribosomal large subunit biogenesis snf2 1.15e-06 16 2069 15 GO:0009123 BP nucleoside monophosphate metabolic process snf2 3.17e-06 15 2069 14 GO:0009161 BP ribonucleoside monophosphate metabolic process snf2 1.06e-07 15 2069 15 GO:0009126 BP purine nucleoside monophosphate metabolic process snf2 3.11e-07 14 2069 14 GO:0009167 BP purine ribonucleoside monophosphate metabolic process snf2 8.67e-06 14 2069 13 GO:0009124 BP nucleoside monophosphate biosynthetic process snf2 9.08e-07 13 2069 13 GO:0009127 BP purine nucleoside monophosphate biosynthetic process snf2 2.65e-06 12 2069 12 GO:0009168 BP purine ribonucleoside monophosphate biosynthetic process snf2 3.51e-07 456 2069 206 GO:0044281 BP small molecule metabolic process snf2 1.27e-07 131 2069 74 GO:0044283 BP small molecule biosynthetic process snf2 3.94e-06 180 2069 91 GO:0042180 BP cellular ketone metabolic process snf2 4.98e-06 176 2069 89 GO:0006082 BP organic acid metabolic process snf2 4.98e-06 176 2069 89 GO:0043436 BP oxoacid metabolic process snf2 4.98e-06 176 2069 89 GO:0019752 BP carboxylic acid metabolic process snf2 1.15e-05 208 2069 101 GO:0005730 CC nucleolus snf2 2.79e-08 89 2069 56 GO:0030312 CC external encapsulating structure snf2 2.79e-08 89 2069 56 GO:0005618 CC cell wall snf2 2.79e-08 89 2069 56 GO:0009277 CC fungal-type cell wall snf2 5.22e-11 142 2069 95 KEGG:03010 ke Ribosome snf2 5.36e-11 200 2069 130 REAC:504343 re Metabolism of proteins snf2 5.35e-09 259 2069 155 REAC:504459 re Gene Expression snf2 4.91e-12 164 2069 113 REAC:504507 re Translation snf2 1.03e-09 139 2069 95 REAC:504506 re Eukaryotic Translation Elongation snf2 1.03e-09 139 2069 95 REAC:504505 re Peptide chain elongation snf2 9.31e-10 137 2069 94 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site snf2 9.31e-10 137 2069 94 REAC:502806 re Hydrolysis of eEF1A:GTP snf2 8.33e-10 135 2069 93 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA snf2 1.03e-09 139 2069 95 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction snf2 1.97e-12 159 2069 111 REAC:504612 re Eukaryotic Translation Initiation snf2 1.97e-12 159 2069 111 REAC:504611 re Cap-dependent Translation Initiation snf2 1.17e-05 74 2069 51 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S snf2 1.17e-05 74 2069 51 REAC:504671 re Translation initiation complex formation snf2 1.17e-05 74 2069 51 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation snf2 1.17e-05 74 2069 51 REAC:504769 re Ribosomal scanning and start codon recognition snf2 1.17e-05 74 2069 51 REAC:504040 re Start codon recognition snf2 1.59e-09 136 2069 93 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit snf2 1.59e-09 136 2069 93 REAC:504077 re The 60S subunit joins the translation initiation complex snf2 1.59e-09 136 2069 93 REAC:502286 re eIF5B:GTP is hydrolyzed and released snf2 1.59e-09 136 2069 93 REAC:504765 re Formation of a pool of free 40S subunits snf2 1.59e-09 136 2069 93 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome snf2 6.47e-13 152 2069 108 REAC:504522 re 3' -UTR-mediated translational regulation snf2 6.47e-13 152 2069 108 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression snf2 2.63e-07 79 2069 57 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit snf2 4.32e-06 76 2069 53 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA snf5 1.6e-06 456 1362 141 GO:0044281 BP small molecule metabolic process snf5 1.76e-08 131 1362 57 GO:0044283 BP small molecule biosynthetic process snf5 6.56e-06 180 1362 65 GO:0042180 BP cellular ketone metabolic process snf5 5.93e-06 176 1362 64 GO:0006082 BP organic acid metabolic process snf5 5.93e-06 176 1362 64 GO:0043436 BP oxoacid metabolic process snf5 5.93e-06 176 1362 64 GO:0019752 BP carboxylic acid metabolic process snf5 4.97e-07 193 1362 72 GO:0034641 BP cellular nitrogen compound metabolic process snf5 1.04e-05 113 1362 45 GO:0044106 BP cellular amine metabolic process snf5 3.28e-06 65 1362 31 GO:0016053 BP organic acid biosynthetic process snf5 3.28e-06 65 1362 31 GO:0046394 BP carboxylic acid biosynthetic process snf5 2.61e-07 98 1362 44 GO:0006520 BP cellular amino acid metabolic process snf5 2.55e-08 89 1362 43 GO:0030312 CC external encapsulating structure snf5 2.55e-08 89 1362 43 GO:0005618 CC cell wall snf5 2.55e-08 89 1362 43 GO:0009277 CC fungal-type cell wall snf6 1.44e-06 328 2630 183 GO:0022613 BP ribonucleoprotein complex biogenesis snf6 4.02e-08 306 2630 178 GO:0042254 BP ribosome biogenesis snf6 5.68e-10 89 2630 67 GO:0030312 CC external encapsulating structure snf6 5.68e-10 89 2630 67 GO:0005618 CC cell wall snf6 5.68e-10 89 2630 67 GO:0009277 CC fungal-type cell wall sok2 2.65e-05 11 215 5 GO:0000786 CC nucleosome sok2 2.65e-05 11 215 5 GO:0000788 CC nuclear nucleosome sok2 0.000414 10 215 4 KEGG:00280 ke Valine, leucine and isoleucine degradation sok2 0.000147 8 215 4 KEGG:00410 ke beta-Alanine metabolism sok2 0.00193 7 215 3 KEGG:00903 ke Limonene and pinene degradation sok2 0.000917 12 215 4 KEGG:00561 ke Glycerolipid metabolism spt20 2.55e-07 328 1929 144 GO:0022613 BP ribonucleoprotein complex biogenesis spt20 3.34e-08 306 1929 139 GO:0042254 BP ribosome biogenesis spt20 2.05e-07 89 1929 51 GO:0030312 CC external encapsulating structure spt20 2.05e-07 89 1929 51 GO:0005618 CC cell wall spt20 2.05e-07 89 1929 51 GO:0009277 CC fungal-type cell wall spt20 8.85e-21 142 1929 105 KEGG:03010 ke Ribosome spt20 3.37e-19 152 1929 112 REAC:504522 re 3' -UTR-mediated translational regulation spt20 3.37e-19 152 1929 112 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression spt20 2.6e-13 79 1929 63 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit spt20 1.71e-06 76 1929 51 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA spt20 3.12e-17 200 1929 134 REAC:504343 re Metabolism of proteins spt20 2.62e-09 259 1929 146 REAC:504459 re Gene Expression spt20 1.63e-17 164 1929 116 REAC:504507 re Translation spt20 2.25e-16 139 1929 101 REAC:504506 re Eukaryotic Translation Elongation spt20 2.25e-16 139 1929 101 REAC:504505 re Peptide chain elongation spt20 1.96e-16 137 1929 100 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site spt20 1.96e-16 137 1929 100 REAC:502806 re Hydrolysis of eEF1A:GTP spt20 3.28e-17 135 1929 100 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA spt20 2.25e-16 139 1929 101 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction spt20 1.2e-18 159 1929 115 REAC:504612 re Eukaryotic Translation Initiation spt20 1.2e-18 159 1929 115 REAC:504611 re Cap-dependent Translation Initiation spt20 5.16e-06 74 1929 49 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S spt20 5.16e-06 74 1929 49 REAC:504671 re Translation initiation complex formation spt20 8.87e-06 73 1929 48 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize spt20 5.16e-06 74 1929 49 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation spt20 5.16e-06 74 1929 49 REAC:504769 re Ribosomal scanning and start codon recognition spt20 8.87e-06 73 1929 48 REAC:503952 re Ribosomal scanning spt20 5.16e-06 74 1929 49 REAC:504040 re Start codon recognition spt20 8.11e-17 136 1929 100 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit spt20 8.11e-17 136 1929 100 REAC:504077 re The 60S subunit joins the translation initiation complex spt20 8.11e-17 136 1929 100 REAC:502286 re eIF5B:GTP is hydrolyzed and released spt20 8.11e-17 136 1929 100 REAC:504765 re Formation of a pool of free 40S subunits spt20 8.11e-17 136 1929 100 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome swi3 7.58e-06 131 1813 63 GO:0044283 BP small molecule biosynthetic process swi3 1.01e-05 39 1813 25 GO:0015077 MF monovalent inorganic cation transmembrane transporter activity swi4 4.75e-09 89 467 25 GO:0030312 CC external encapsulating structure swi4 4.75e-09 89 467 25 GO:0005618 CC cell wall swi4 4.75e-09 89 467 25 GO:0009277 CC fungal-type cell wall swi4 1.45e-07 11 467 8 GO:0000786 CC nucleosome swi4 1.45e-07 11 467 8 GO:0000788 CC nuclear nucleosome swi4 6.32e-05 11 467 6 GO:0005199 MF structural constituent of cell wall swi4 0.00106 29 467 8 KEGG:00330 ke Arginine and proline metabolism swi4 0.000188 29 467 9 KEGG:00250 ke Alanine, aspartate and glutamate metabolism swi4 0.000249 49 467 12 REAC:504363 re Metabolism of amino acids swi4 0.000636 159 467 24 REAC:504612 re Eukaryotic Translation Initiation swi4 0.000636 159 467 24 REAC:504611 re Cap-dependent Translation Initiation tup1 1.13e-05 328 2514 172 GO:0022613 BP ribonucleoprotein complex biogenesis tup1 1.1e-06 306 2514 166 GO:0042254 BP ribosome biogenesis yap1 7.12e-06 691 114 29 GO:0050896 BP response to stimulus yap1 8.47e-05 41 114 6 GO:0009605 BP response to external stimulus yap1 5.43e-05 38 114 6 GO:0071496 BP cellular response to external stimulus yap1 8.47e-05 41 114 6 GO:0009991 BP response to extracellular stimulus yap1 8.47e-05 41 114 6 GO:0031667 BP response to nutrient levels yap1 6.58e-05 429 114 20 GO:0006950 BP response to stress yap1 4.22e-06 25 114 6 GO:0042594 BP response to starvation yap1 4.45e-06 390 114 21 GO:0042221 BP response to chemical stimulus yap1 1.05e-07 61 114 10 GO:0006979 BP response to oxidative stress yap1 5.43e-05 38 114 6 GO:0031668 BP cellular response to extracellular stimulus yap1 5.43e-05 38 114 6 GO:0031669 BP cellular response to nutrient levels yap1 5.15e-07 5 114 4 GO:0043562 BP cellular response to nitrogen levels yap1 4.22e-06 25 114 6 GO:0009267 BP cellular response to starvation yap1 5.15e-07 5 114 4 GO:0006995 BP cellular response to nitrogen starvation yap1 1.23e-05 9 114 4 GO:0042597 CC periplasmic space yap1 1.23e-05 9 114 4 GO:0030287 CC cell wall-bounded periplasmic space yap1 3.48e-05 91 114 9 GO:0016491 MF oxidoreductase activity yap1 6.58e-05 13 114 4 GO:0016705 MF oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen yap1 0.000113 6 114 3 GO:0051920 MF peroxiredoxin activity yap1 0.000113 6 114 3 GO:0008379 MF thioredoxin peroxidase activity yap1 9.08e-05 14 114 4 GO:0015238 MF drug transmembrane transporter activity yap1 1.02e-05 17 114 5 KEGG:00910 ke Nitrogen metabolism yap1 0.000365 19 114 4 KEGG:00480 ke Glutathione metabolism yap1 1.36e-05 9 114 4 KEGG:00460 ke Cyanoamino acid metabolism yap1 1.09e-05 29 114 6 KEGG:00250 ke Alanine, aspartate and glutamate metabolism yap1 0.000229 18 114 4 REAC:504376 re Purine biosynthesis yap1 0.000189 7 114 3 REAC:504388 re dGTP formation yap1 0.000189 7 114 3 REAC:504375 re dATP formation yap1 0.000299 8 114 3 REAC:504465 re Synthesis of deoxyribonucleoside 5'-diphosphates from ribonucleoside 5'-diphosphates yap1 0.000109 6 114 3 REAC:504467 re Reduction of cytosolic ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates by ribonucleotide reductase and thioredoxin yap1 0.000109 6 114 3 REAC:504469 re Reduction of nuclear ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates by ribonucleotide reductase and thioredoxin yer130c 0.000427 40 161 6 KEGG:00500 ke Starch and sucrose metabolism yer184c 0.000317 40 203 7 KEGG:00500 ke Starch and sucrose metabolism yer184c 6.31e-05 8 203 4 REAC:504500 re Glycogen synthesis yjl103c 1.65e-06 5 146 4 GO:0043562 BP cellular response to nitrogen levels yjl103c 1.65e-06 5 146 4 GO:0006995 BP cellular response to nitrogen starvation yjl103c 3.84e-05 9 146 4 GO:0042597 CC periplasmic space yjl103c 3.84e-05 9 146 4 GO:0030287 CC cell wall-bounded periplasmic space yjl103c 8.56e-09 142 146 17 KEGG:03010 ke Ribosome yjl103c 4.11e-05 9 146 4 KEGG:00460 ke Cyanoamino acid metabolism yjl103c 0.000671 17 146 4 KEGG:00910 ke Nitrogen metabolism yjl103c 0.000164 200 146 18 REAC:504343 re Metabolism of proteins yjl103c 0.000512 259 146 20 REAC:504459 re Gene Expression yjl103c 8.69e-06 164 146 18 REAC:504507 re Translation yjl103c 3.87e-06 139 146 17 REAC:504506 re Eukaryotic Translation Elongation yjl103c 3.87e-06 139 146 17 REAC:504505 re Peptide chain elongation yjl103c 3.12e-06 137 146 17 REAC:502806 re Hydrolysis of eEF1A:GTP yjl103c 3.12e-06 137 146 17 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site yjl103c 2.5e-06 135 146 17 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA yjl103c 3.87e-06 139 146 17 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction yjl103c 5.39e-06 159 146 18 REAC:504612 re Eukaryotic Translation Initiation yjl103c 5.39e-06 159 146 18 REAC:504611 re Cap-dependent Translation Initiation yjl103c 2.79e-06 136 146 17 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit yjl103c 2.79e-06 136 146 17 REAC:504077 re The 60S subunit joins the translation initiation complex yjl103c 2.79e-06 136 146 17 REAC:502286 re eIF5B:GTP is hydrolyzed and released yjl103c 2.79e-06 136 146 17 REAC:504765 re Formation of a pool of free 40S subunits yjl103c 2.79e-06 136 146 17 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome yjl103c 2.66e-06 152 146 18 REAC:504522 re 3' -UTR-mediated translational regulation yjl103c 2.66e-06 152 146 18 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression yjl103c 3.13e-06 79 146 13 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit aca1 3.2e-05 114 286 16 GO:0000746 BP conjugation aca1 3.2e-05 114 286 16 GO:0000747 BP conjugation with cellular fusion aca1 5.78e-09 89 286 19 GO:0030312 CC external encapsulating structure aca1 5.78e-09 89 286 19 GO:0005618 CC cell wall aca1 5.78e-09 89 286 19 GO:0009277 CC fungal-type cell wall aca1 8.44e-05 3 286 3 GO:0050839 MF cell adhesion molecule binding aca1 0.000921 8 286 4 KEGG:00980 ke Metabolism of xenobiotics by cytochrome P450 ace2 4.33e-05 31 562 11 GO:0009066 BP aspartate family amino acid metabolic process ace2 3.32e-05 193 562 35 GO:0034641 BP cellular nitrogen compound metabolic process ace2 1.19e-07 456 562 74 GO:0044281 BP small molecule metabolic process ace2 3.03e-06 131 562 29 GO:0044283 BP small molecule biosynthetic process ace2 2.52e-06 180 562 36 GO:0042180 BP cellular ketone metabolic process ace2 4.51e-05 113 562 24 GO:0055086 BP cellular nucleobase, nucleoside and nucleotide metabolic process ace2 4.01e-06 176 562 35 GO:0006082 BP organic acid metabolic process ace2 4.01e-06 176 562 35 GO:0043436 BP oxoacid metabolic process ace2 4.01e-06 176 562 35 GO:0019752 BP carboxylic acid metabolic process ace2 8.97e-05 125 562 25 GO:0006519 BP cellular amino acid and derivative metabolic process ace2 1.2e-05 23 562 10 GO:0046165 BP alcohol biosynthetic process ace2 1.44e-05 15 562 8 GO:0046364 BP monosaccharide biosynthetic process ace2 2.38e-05 12 562 7 GO:0019319 BP hexose biosynthetic process ace2 7.7e-05 18 562 8 GO:0006090 BP pyruvate metabolic process ace2 7.76e-05 10 562 6 GO:0006094 BP gluconeogenesis ace2 6.21e-09 89 562 27 GO:0030312 CC external encapsulating structure ace2 6.21e-09 89 562 27 GO:0005618 CC cell wall ace2 6.21e-09 89 562 27 GO:0009277 CC fungal-type cell wall ace2 4.26e-05 268 562 44 GO:0005215 MF transporter activity ace2 2.01e-05 244 562 42 GO:0022892 MF substrate-specific transporter activity ace2 0.000953 10 562 6 KEGG:01040 ke Biosynthesis of unsaturated fatty acids ace2 0.000825 13 562 7 KEGG:00300 ke Lysine biosynthesis ace2 5.19e-06 616 562 117 KEGG:01100 ke Metabolic pathways ace2 0.000679 142 562 34 KEGG:03010 ke Ribosome ace2 0.000103 47 562 17 KEGG:00010 ke Glycolysis / Gluconeogenesis ace2 0.000724 29 562 11 REAC:504367 re Purine metabolism ace2 0.000867 136 562 31 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit ace2 0.000867 136 562 31 REAC:504077 re The 60S subunit joins the translation initiation complex ace2 0.000867 136 562 31 REAC:502286 re eIF5B:GTP is hydrolyzed and released ace2 0.000569 139 562 32 REAC:504506 re Eukaryotic Translation Elongation ace2 0.000569 139 562 32 REAC:504505 re Peptide chain elongation ace2 0.000425 137 562 32 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site ace2 0.000425 137 562 32 REAC:502806 re Hydrolysis of eEF1A:GTP ace2 0.000753 135 562 31 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA ace2 0.000569 139 562 32 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction ace2 0.000867 136 562 31 REAC:504765 re Formation of a pool of free 40S subunits ace2 0.000867 136 562 31 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome ace2 0.000857 48 562 15 REAC:504354 re Diabetes pathways ace2 0.000857 48 562 15 REAC:504352 re Glucose Regulation of Insulin Secretion ace2 0.000108 17 562 9 REAC:504394 re Glycolysis aro80 1.13e-07 23 347 10 GO:0046165 BP alcohol biosynthetic process aro80 3.11e-07 15 347 8 GO:0046364 BP monosaccharide biosynthetic process aro80 2.76e-08 12 347 8 GO:0019319 BP hexose biosynthetic process aro80 5.53e-09 18 347 10 GO:0006090 BP pyruvate metabolic process aro80 1.33e-07 10 347 7 GO:0006094 BP gluconeogenesis aro80 3.08e-05 180 347 24 GO:0042180 BP cellular ketone metabolic process aro80 2.1e-05 176 347 24 GO:0006082 BP organic acid metabolic process aro80 2.1e-05 176 347 24 GO:0043436 BP oxoacid metabolic process aro80 2.1e-05 176 347 24 GO:0019752 BP carboxylic acid metabolic process aro80 2.54e-06 47 347 15 KEGG:00010 ke Glycolysis / Gluconeogenesis aro80 1.89e-11 142 347 37 KEGG:03010 ke Ribosome aro80 3.3e-05 45 347 14 REAC:504348 re Glucose metabolism aro80 1.15e-06 22 347 11 REAC:504355 re Gluconeogenesis aro80 7.88e-06 5 347 5 REAC:503441 re Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate aro80 0.000323 48 347 13 REAC:504354 re Diabetes pathways aro80 0.000323 48 347 13 REAC:504352 re Glucose Regulation of Insulin Secretion aro80 1.41e-09 17 347 12 REAC:504394 re Glycolysis aro80 7.88e-06 5 347 5 REAC:499691 re 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O aro80 4.33e-08 200 347 41 REAC:504343 re Metabolism of proteins aro80 3.84e-08 259 347 48 REAC:504459 re Gene Expression aro80 9.85e-10 164 347 39 REAC:504507 re Translation aro80 8.84e-11 139 347 37 REAC:504506 re Eukaryotic Translation Elongation aro80 8.84e-11 139 347 37 REAC:504505 re Peptide chain elongation aro80 5.39e-11 137 347 37 REAC:502806 re Hydrolysis of eEF1A:GTP aro80 5.39e-11 137 347 37 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site aro80 1.77e-10 135 347 36 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA aro80 8.84e-11 139 347 37 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction aro80 1.62e-09 159 347 38 REAC:504612 re Eukaryotic Translation Initiation aro80 1.62e-09 159 347 38 REAC:504611 re Cap-dependent Translation Initiation aro80 0.000307 67 347 16 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex aro80 0.000307 67 347 16 REAC:502531 re Formation of the 43S pre-initiation complex aro80 2.26e-10 136 347 36 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit aro80 2.26e-10 136 347 36 REAC:504077 re The 60S subunit joins the translation initiation complex aro80 2.26e-10 136 347 36 REAC:502286 re eIF5B:GTP is hydrolyzed and released aro80 4.2e-11 136 347 37 REAC:504765 re Formation of a pool of free 40S subunits aro80 4.2e-11 136 347 37 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome aro80 3.58e-10 152 347 38 REAC:504522 re 3' -UTR-mediated translational regulation aro80 3.58e-10 152 347 38 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression aro80 9.38e-07 79 347 22 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit cat8 8.19e-06 34 60 5 GO:0043900 BP regulation of multi-organism process cat8 8.19e-06 34 60 5 GO:0046999 BP regulation of conjugation cat8 8.19e-06 34 60 5 GO:0031137 BP regulation of conjugation with cellular fusion cat8 3e-06 28 60 5 GO:0032005 BP signal transduction involved in conjugation with cellular fusion cat8 8.82e-07 128 60 9 GO:0051704 BP multi-organism process cat8 3.27e-07 114 60 9 GO:0000746 BP conjugation cat8 2.96e-05 302 60 11 GO:0000003 BP reproduction cat8 1.1e-06 215 60 11 GO:0019953 BP sexual reproduction cat8 3.27e-07 114 60 9 GO:0000747 BP conjugation with cellular fusion cat8 3.14e-05 8 60 3 GO:0022610 BP biological adhesion cat8 3.14e-05 8 60 3 GO:0007155 BP cell adhesion cat8 5.7e-06 5 60 3 GO:0016337 BP cell-cell adhesion cat8 2.29e-06 4 60 3 GO:0007157 BP heterophilic cell adhesion cat8 2.29e-06 4 60 3 GO:0000771 BP agglutination involved in conjugation cat8 5.16e-06 158 60 9 GO:0010033 BP response to organic substance cat8 4.12e-08 90 60 9 GO:0019236 BP response to pheromone cat8 2.87e-09 67 60 9 GO:0000749 BP response to pheromone during conjugation with cellular fusion cat8 2.29e-06 4 60 3 GO:0000752 BP agglutination involved in conjugation with cellular fusion cat8 5.11e-05 49 60 5 GO:0007166 BP cell surface receptor linked signal transduction cat8 5.09e-06 31 60 5 GO:0007186 BP G-protein coupled receptor protein signaling pathway cat8 3e-06 28 60 5 GO:0000750 BP pheromone-dependent signal transduction involved in conjugation with cellular fusion cat8 8.01e-06 89 60 7 GO:0030312 CC external encapsulating structure cat8 8.01e-06 89 60 7 GO:0005618 CC cell wall cat8 8.01e-06 89 60 7 GO:0009277 CC fungal-type cell wall cat8 7.1e-05 2 60 2 GO:0004930 MF G-protein coupled receptor activity cat8 7.1e-05 2 60 2 GO:0016503 MF pheromone receptor activity cat8 7.1e-05 2 60 2 GO:0004932 MF mating-type factor pheromone receptor activity cat8 5.77e-07 3 60 3 GO:0050839 MF cell adhesion molecule binding cat8 0.000336 55 60 5 KEGG:04011 ke MAPK signaling pathway - yeast cat8 0.00107 18 60 3 KEGG:00290 ke Valine, leucine and isoleucine biosynthesis cdc73 3.23e-06 456 796 90 GO:0044281 BP small molecule metabolic process cdc73 3.06e-08 131 796 40 GO:0044283 BP small molecule biosynthetic process cdc73 6.32e-06 180 796 44 GO:0042180 BP cellular ketone metabolic process cdc73 1.94e-05 176 796 42 GO:0006082 BP organic acid metabolic process cdc73 1.94e-05 176 796 42 GO:0043436 BP oxoacid metabolic process cdc73 1.94e-05 176 796 42 GO:0019752 BP carboxylic acid metabolic process cdc73 4.51e-05 125 796 32 GO:0006519 BP cellular amino acid and derivative metabolic process cdc73 7.38e-06 39 796 16 GO:0006575 BP cellular amino acid derivative metabolic process cdc73 5.94e-07 23 796 13 GO:0046165 BP alcohol biosynthetic process cdc73 1.83e-05 15 796 9 GO:0046364 BP monosaccharide biosynthetic process cdc73 1.86e-05 12 796 8 GO:0019319 BP hexose biosynthetic process cdc73 4.09e-05 10 796 7 GO:0006094 BP gluconeogenesis cdc73 4.13e-05 193 796 44 GO:0034641 BP cellular nitrogen compound metabolic process cdc73 1.42e-13 89 796 39 GO:0030312 CC external encapsulating structure cdc73 1.42e-13 89 796 39 GO:0005618 CC cell wall cdc73 1.42e-13 89 796 39 GO:0009277 CC fungal-type cell wall cdc73 0.000381 29 796 12 KEGG:00330 ke Arginine and proline metabolism cdc73 1.44e-05 29 796 14 KEGG:00250 ke Alanine, aspartate and glutamate metabolism cdc73 5.14e-07 616 796 124 KEGG:01100 ke Metabolic pathways cdc73 0.0022 18 796 8 KEGG:00290 ke Valine, leucine and isoleucine biosynthesis cdc73 0.00226 11 796 6 KEGG:00770 ke Pantothenate and CoA biosynthesis cdc73 0.00161 8 796 5 REAC:504416 re Synaptic Transmission cdc73 0.00161 8 796 5 REAC:504415 re Transmission across Chemical Synapses cdc73 0.00139 5 796 4 REAC:504366 re Purine salvage reactions cdc73 0.00139 5 796 4 REAC:504460 re Ribonucleotide salvage cdc73 0.0052 22 796 8 REAC:504355 re Gluconeogenesis cdc73 0.00237 3 796 3 REAC:499530 re 1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+ cdc73 0.00139 5 796 4 REAC:503441 re Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate cdc73 0.000101 17 796 9 REAC:504394 re Glycolysis cdc73 0.00139 5 796 4 REAC:499691 re 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O cdc73 0.00237 3 796 3 REAC:504608 re Glyceraldehyde 3-phosphate, NAD+, and orthophosphate react to form 1,3-bisphosphoglycerate, NADH, and H+ cdc73 0.00237 3 796 3 REAC:501949 re D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ cdc73 1.38e-07 49 796 21 REAC:504363 re Metabolism of amino acids cdc73 0.00784 7 796 4 REAC:504731 re Metabolism of polyamines cdc73 0.00949 11 796 5 REAC:504513 re Ornithine and proline metabolism cdc73 0.00855 4 796 3 REAC:504503 re Branched-chain amino acid catabolism cdc73 0.00237 3 796 3 REAC:504502 re Isoleucine catabolism cdc73 0.00237 3 796 3 REAC:504403 re Tryptophan catabolism cdc73 0.00161 8 796 5 REAC:504362 re Urea synthesis cdc73 0.000669 29 796 11 REAC:504358 re Metabolism of vitamins and cofactors cdc73 0.000669 29 796 11 REAC:504357 re Metabolism of water-soluble vitamins and cofactors cdc73 0.000691 10 796 6 REAC:504404 re Nicotinate metabolism cin5 2.95e-05 18 660 9 GO:0006090 BP pyruvate metabolic process cin5 1.01e-08 89 660 29 GO:0030312 CC external encapsulating structure cin5 1.01e-08 89 660 29 GO:0005618 CC cell wall cin5 1.01e-08 89 660 29 GO:0009277 CC fungal-type cell wall cin5 5.62e-27 142 660 73 KEGG:03010 ke Ribosome cin5 1.58e-15 200 660 78 REAC:504343 re Metabolism of proteins cin5 3.32e-11 259 660 84 REAC:504459 re Gene Expression cin5 1.3e-17 164 660 72 REAC:504507 re Translation cin5 1.82e-21 139 660 70 REAC:504506 re Eukaryotic Translation Elongation cin5 1.82e-21 139 660 70 REAC:504505 re Peptide chain elongation cin5 5.77e-22 137 660 70 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site cin5 5.77e-22 137 660 70 REAC:502806 re Hydrolysis of eEF1A:GTP cin5 1.33e-21 135 660 69 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA cin5 1.82e-21 139 660 70 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction cin5 7.55e-18 159 660 71 REAC:504612 re Eukaryotic Translation Initiation cin5 7.55e-18 159 660 71 REAC:504611 re Cap-dependent Translation Initiation cin5 3.41e-06 74 660 30 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S cin5 3.41e-06 74 660 30 REAC:504671 re Translation initiation complex formation cin5 2.41e-06 73 660 30 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize cin5 3.41e-06 74 660 30 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation cin5 3.41e-06 74 660 30 REAC:504769 re Ribosomal scanning and start codon recognition cin5 2.41e-06 73 660 30 REAC:503952 re Ribosomal scanning cin5 3.41e-06 74 660 30 REAC:504040 re Start codon recognition cin5 2.41e-07 67 660 30 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex cin5 2.41e-07 67 660 30 REAC:502531 re Formation of the 43S pre-initiation complex cin5 2.37e-21 136 660 69 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit cin5 2.37e-21 136 660 69 REAC:504077 re The 60S subunit joins the translation initiation complex cin5 2.37e-21 136 660 69 REAC:502286 re eIF5B:GTP is hydrolyzed and released cin5 3.21e-22 136 660 70 REAC:504765 re Formation of a pool of free 40S subunits cin5 3.21e-22 136 660 70 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome cin5 2.7e-19 152 660 71 REAC:504522 re 3' -UTR-mediated translational regulation cin5 2.7e-19 152 660 71 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression cin5 1.53e-12 79 660 41 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit cin5 1.92e-06 76 660 31 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA cin5 0.000231 17 660 10 REAC:504394 re Glycolysis cup9 1.32e-05 23 1012 13 GO:0046165 BP alcohol biosynthetic process cup9 2.22e-07 18 1012 13 GO:0006090 BP pyruvate metabolic process cup9 1.65e-12 89 1012 43 GO:0030312 CC external encapsulating structure cup9 1.65e-12 89 1012 43 GO:0005618 CC cell wall cup9 1.65e-12 89 1012 43 GO:0009277 CC fungal-type cell wall cup9 1.13e-05 244 1012 66 GO:0022892 MF substrate-specific transporter activity cup9 2.47e-18 142 1012 77 KEGG:03010 ke Ribosome cup9 5.39e-16 152 1012 78 REAC:504522 re 3' -UTR-mediated translational regulation cup9 5.39e-16 152 1012 78 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression cup9 1.1e-09 79 1012 43 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit cup9 1.06e-05 76 1012 35 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA cup9 2.57e-12 200 1012 87 REAC:504343 re Metabolism of proteins cup9 4.75e-09 259 1012 97 REAC:504459 re Gene Expression cup9 9.82e-15 164 1012 80 REAC:504507 re Translation cup9 1.89e-18 139 1012 77 REAC:504506 re Eukaryotic Translation Elongation cup9 1.89e-18 139 1012 77 REAC:504505 re Peptide chain elongation cup9 3.16e-18 137 1012 76 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site cup9 3.16e-18 137 1012 76 REAC:502806 re Hydrolysis of eEF1A:GTP cup9 5.26e-18 135 1012 75 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA cup9 1.89e-18 139 1012 77 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction cup9 1.72e-14 159 1012 78 REAC:504612 re Eukaryotic Translation Initiation cup9 1.72e-14 159 1012 78 REAC:504611 re Cap-dependent Translation Initiation cup9 4.9e-06 74 1012 35 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S cup9 4.9e-06 74 1012 35 REAC:504671 re Translation initiation complex formation cup9 3.27e-06 73 1012 35 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize cup9 4.9e-06 74 1012 35 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation cup9 4.9e-06 74 1012 35 REAC:504769 re Ribosomal scanning and start codon recognition cup9 3.27e-06 73 1012 35 REAC:503952 re Ribosomal scanning cup9 4.9e-06 74 1012 35 REAC:504040 re Start codon recognition cup9 2.19e-07 67 1012 35 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex cup9 2.19e-07 67 1012 35 REAC:502531 re Formation of the 43S pre-initiation complex cup9 9.62e-18 136 1012 75 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit cup9 9.62e-18 136 1012 75 REAC:504077 re The 60S subunit joins the translation initiation complex cup9 9.62e-18 136 1012 75 REAC:502286 re eIF5B:GTP is hydrolyzed and released cup9 1.71e-18 136 1012 76 REAC:504765 re Formation of a pool of free 40S subunits cup9 1.71e-18 136 1012 76 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome esc2 9.1e-07 23 659 12 GO:0046165 BP alcohol biosynthetic process esc2 4.85e-06 15 659 9 GO:0046364 BP monosaccharide biosynthetic process esc2 2.87e-07 12 659 9 GO:0019319 BP hexose biosynthetic process esc2 3.07e-07 18 659 11 GO:0006090 BP pyruvate metabolic process esc2 6.15e-07 10 659 8 GO:0006094 BP gluconeogenesis esc2 1.65e-10 89 659 32 GO:0030312 CC external encapsulating structure esc2 1.65e-10 89 659 32 GO:0005618 CC cell wall esc2 1.65e-10 89 659 32 GO:0009277 CC fungal-type cell wall esc2 7.66e-05 12 659 7 GO:0005576 CC extracellular region esc2 2.36e-05 47 659 19 KEGG:00010 ke Glycolysis / Gluconeogenesis esc2 1.57e-15 142 659 59 KEGG:03010 ke Ribosome esc2 0.000275 8 659 6 KEGG:00980 ke Metabolism of xenobiotics by cytochrome P450 esc2 5.67e-07 17 659 12 REAC:504394 re Glycolysis esc2 1e-04 5 659 5 REAC:499691 re 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O esc2 3.1e-11 200 659 64 REAC:504343 re Metabolism of proteins esc2 3.59e-12 259 659 77 REAC:504459 re Gene Expression esc2 1.82e-13 164 659 60 REAC:504507 re Translation esc2 2.17e-15 139 659 57 REAC:504506 re Eukaryotic Translation Elongation esc2 2.17e-15 139 659 57 REAC:504505 re Peptide chain elongation esc2 9.44e-16 137 659 57 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site esc2 9.44e-16 137 659 57 REAC:502806 re Hydrolysis of eEF1A:GTP esc2 2.33e-15 135 659 56 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA esc2 2.17e-15 139 659 57 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction esc2 1.54e-13 159 659 59 REAC:504612 re Eukaryotic Translation Initiation esc2 1.54e-13 159 659 59 REAC:504611 re Cap-dependent Translation Initiation esc2 6.11e-05 74 659 25 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S esc2 6.11e-05 74 659 25 REAC:504671 re Translation initiation complex formation esc2 4.68e-05 73 659 25 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize esc2 6.11e-05 74 659 25 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation esc2 6.11e-05 74 659 25 REAC:504769 re Ribosomal scanning and start codon recognition esc2 4.68e-05 73 659 25 REAC:503952 re Ribosomal scanning esc2 6.11e-05 74 659 25 REAC:504040 re Start codon recognition esc2 2.87e-05 67 659 24 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex esc2 2.87e-05 67 659 24 REAC:502531 re Formation of the 43S pre-initiation complex esc2 3.53e-15 136 659 56 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit esc2 3.53e-15 136 659 56 REAC:504077 re The 60S subunit joins the translation initiation complex esc2 3.53e-15 136 659 56 REAC:502286 re eIF5B:GTP is hydrolyzed and released esc2 6.18e-16 136 659 57 REAC:504765 re Formation of a pool of free 40S subunits esc2 6.18e-16 136 659 57 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome esc2 1.23e-14 152 659 59 REAC:504522 re 3' -UTR-mediated translational regulation esc2 1.23e-14 152 659 59 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression esc2 2.5e-10 79 659 35 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit esc2 0.000102 76 659 25 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA esc2 0.000179 22 659 11 REAC:504355 re Gluconeogenesis esc2 1e-04 5 659 5 REAC:503441 re Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate gal11 8.38e-07 11 847 9 GO:0000786 CC nucleosome gal11 8.38e-07 11 847 9 GO:0000788 CC nuclear nucleosome gal11 5.39e-06 89 847 29 GO:0030312 CC external encapsulating structure gal11 5.39e-06 89 847 29 GO:0005618 CC cell wall gal11 5.39e-06 89 847 29 GO:0009277 CC fungal-type cell wall gal11 4.68e-05 268 847 61 GO:0005215 MF transporter activity gal11 3.83e-05 244 847 57 GO:0022892 MF substrate-specific transporter activity gal11 7.19e-25 142 847 82 KEGG:03010 ke Ribosome gal11 1.7e-17 200 847 92 REAC:504343 re Metabolism of proteins gal11 8.15e-15 259 847 104 REAC:504459 re Gene Expression gal11 7.88e-19 164 847 83 REAC:504507 re Translation gal11 2.65e-21 139 847 78 REAC:504506 re Eukaryotic Translation Elongation gal11 2.65e-21 139 847 78 REAC:504505 re Peptide chain elongation gal11 7.16e-22 137 847 78 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site gal11 7.16e-22 137 847 78 REAC:502806 re Hydrolysis of eEF1A:GTP gal11 1.86e-22 135 847 78 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA gal11 2.65e-21 139 847 78 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction gal11 5.12e-20 159 847 83 REAC:504612 re Eukaryotic Translation Initiation gal11 5.12e-20 159 847 83 REAC:504611 re Cap-dependent Translation Initiation gal11 1.62e-07 67 847 34 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex gal11 1.62e-07 67 847 34 REAC:502531 re Formation of the 43S pre-initiation complex gal11 3.67e-22 136 847 78 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit gal11 3.67e-22 136 847 78 REAC:504077 re The 60S subunit joins the translation initiation complex gal11 3.67e-22 136 847 78 REAC:502286 re eIF5B:GTP is hydrolyzed and released gal11 5.15e-23 136 847 79 REAC:504765 re Formation of a pool of free 40S subunits gal11 5.15e-23 136 847 79 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome gal11 5.2e-21 152 847 82 REAC:504522 re 3' -UTR-mediated translational regulation gal11 5.2e-21 152 847 82 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression gal11 1.84e-14 79 847 48 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit gal4 5.51e-08 2335 1087 488 GO:0005737 CC cytoplasm gal4 6.03e-07 1796 1087 384 GO:0044444 CC cytoplasmic part gal4 9.93e-06 136 1087 45 GO:0071212 CC subsynaptic reticulum gal4 2.43e-06 221 1087 67 GO:0005783 CC endoplasmic reticulum gal4 9.93e-06 136 1087 45 GO:0044432 CC endoplasmic reticulum part gal4 1.25e-05 133 1087 44 GO:0042175 CC nuclear envelope-endoplasmic reticulum network gal4 1.62e-05 122 1087 41 GO:0005789 CC endoplasmic reticulum membrane gal4 2.87e-11 89 1087 43 GO:0030312 CC external encapsulating structure gal4 2.87e-11 89 1087 43 GO:0005618 CC cell wall gal4 2.87e-11 89 1087 43 GO:0009277 CC fungal-type cell wall gal4 2.2e-08 268 1087 84 GO:0005215 MF transporter activity gal4 2.81e-08 244 1087 78 GO:0022892 MF substrate-specific transporter activity gal4 6.42e-17 142 1087 79 KEGG:03010 ke Ribosome gal4 7.48e-15 152 1087 79 REAC:504522 re 3' -UTR-mediated translational regulation gal4 7.48e-15 152 1087 79 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression gal4 4.57e-10 79 1087 45 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit gal4 4.53e-12 200 1087 90 REAC:504343 re Metabolism of proteins gal4 1.63e-08 259 1087 100 REAC:504459 re Gene Expression gal4 3.66e-14 164 1087 82 REAC:504507 re Translation gal4 2.58e-17 139 1087 78 REAC:504506 re Eukaryotic Translation Elongation gal4 2.58e-17 139 1087 78 REAC:504505 re Peptide chain elongation gal4 4.03e-17 137 1087 77 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site gal4 4.03e-17 137 1087 77 REAC:502806 re Hydrolysis of eEF1A:GTP gal4 6.28e-17 135 1087 76 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA gal4 2.58e-17 139 1087 78 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction gal4 5.65e-14 159 1087 80 REAC:504612 re Eukaryotic Translation Initiation gal4 5.65e-14 159 1087 80 REAC:504611 re Cap-dependent Translation Initiation gal4 3.8e-06 67 1087 34 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex gal4 3.8e-06 67 1087 34 REAC:502531 re Formation of the 43S pre-initiation complex gal4 1.15e-16 136 1087 76 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit gal4 1.15e-16 136 1087 76 REAC:504077 re The 60S subunit joins the translation initiation complex gal4 1.15e-16 136 1087 76 REAC:502286 re eIF5B:GTP is hydrolyzed and released gal4 2.19e-17 136 1087 77 REAC:504765 re Formation of a pool of free 40S subunits gal4 2.19e-17 136 1087 77 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome gcn4 1.17e-06 89 272 16 GO:0030312 CC external encapsulating structure gcn4 1.17e-06 89 272 16 GO:0005618 CC cell wall gcn4 1.17e-06 89 272 16 GO:0009277 CC fungal-type cell wall gcn4 8.44e-05 3 272 3 GO:0050839 MF cell adhesion molecule binding gcn4 0.00181 47 272 9 KEGG:00010 ke Glycolysis / Gluconeogenesis gcn4 6.76e-06 142 272 23 KEGG:03010 ke Ribosome gcn4 0.000192 22 272 7 REAC:504355 re Gluconeogenesis gcn4 0.000224 3 272 3 REAC:499530 re 1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+ gcn4 5.51e-06 152 272 23 REAC:504522 re 3' -UTR-mediated translational regulation gcn4 5.51e-06 152 272 23 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression gcn4 0.000128 79 272 14 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit gcn4 0.000216 200 272 24 REAC:504343 re Metabolism of proteins gcn4 3e-04 259 272 28 REAC:504459 re Gene Expression gcn4 5.68e-06 164 272 24 REAC:504507 re Translation gcn4 2.03e-07 139 272 24 REAC:504506 re Eukaryotic Translation Elongation gcn4 2.03e-07 139 272 24 REAC:504505 re Peptide chain elongation gcn4 1.5e-07 137 272 24 REAC:502806 re Hydrolysis of eEF1A:GTP gcn4 1.5e-07 137 272 24 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site gcn4 5.6e-07 135 272 23 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA gcn4 2.03e-07 139 272 24 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction gcn4 1.27e-05 159 272 23 REAC:504612 re Eukaryotic Translation Initiation gcn4 1.27e-05 159 272 23 REAC:504611 re Cap-dependent Translation Initiation gcn4 6.48e-07 136 272 23 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit gcn4 6.48e-07 136 272 23 REAC:504077 re The 60S subunit joins the translation initiation complex gcn4 6.48e-07 136 272 23 REAC:502286 re eIF5B:GTP is hydrolyzed and released gcn4 6.48e-07 136 272 23 REAC:504765 re Formation of a pool of free 40S subunits gcn4 6.48e-07 136 272 23 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome gcn4 2.78e-05 17 272 7 REAC:504394 re Glycolysis gcn4 0.000224 3 272 3 REAC:504608 re Glyceraldehyde 3-phosphate, NAD+, and orthophosphate react to form 1,3-bisphosphoglycerate, NADH, and H+ gcn4 0.000224 3 272 3 REAC:501949 re D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ gln3 1.4e-05 456 596 73 GO:0044281 BP small molecule metabolic process gln3 8.17e-06 131 596 30 GO:0044283 BP small molecule biosynthetic process gln3 3.02e-05 113 596 26 GO:0055086 BP cellular nucleobase, nucleoside and nucleotide metabolic process gln3 3e-05 23 596 10 GO:0046165 BP alcohol biosynthetic process gln3 2.3e-05 193 596 38 GO:0034641 BP cellular nitrogen compound metabolic process gln3 8.74e-05 21 596 9 GO:0019674 BP NAD metabolic process gln3 4.7e-05 12 596 7 GO:0019319 BP hexose biosynthetic process gln3 9.19e-07 89 596 25 GO:0030312 CC external encapsulating structure gln3 9.19e-07 89 596 25 GO:0005618 CC cell wall gln3 9.19e-07 89 596 25 GO:0009277 CC fungal-type cell wall gln3 0.000282 47 596 16 KEGG:00010 ke Glycolysis / Gluconeogenesis gln3 0.000328 616 596 108 KEGG:01100 ke Metabolic pathways gln3 0.000217 6 596 5 REAC:504467 re Reduction of cytosolic ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates by ribonucleotide reductase and thioredoxin gln3 0.000139 29 596 12 REAC:504367 re Purine metabolism gln3 5.23e-06 6 596 6 REAC:504411 re De novo synthesis of IMP gln3 3.15e-05 22 596 11 REAC:504355 re Gluconeogenesis gln3 4.05e-05 5 596 5 REAC:503441 re Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate gln3 7.51e-05 49 596 17 REAC:504363 re Metabolism of amino acids gln3 0.000217 6 596 5 REAC:504469 re Reduction of nuclear ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates by ribonucleotide reductase and thioredoxin gln3 0.000678 7 596 5 REAC:504375 re dATP formation gln3 0.000101 17 596 9 REAC:504394 re Glycolysis gln3 4.05e-05 5 596 5 REAC:499691 re 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O gln3 0.000678 7 596 5 REAC:504388 re dGTP formation hap5 4.95e-09 89 262 19 GO:0030312 CC external encapsulating structure hap5 4.95e-09 89 262 19 GO:0005618 CC cell wall hap5 4.95e-09 89 262 19 GO:0009277 CC fungal-type cell wall hap5 8.21e-05 3 262 3 GO:0050839 MF cell adhesion molecule binding hap5 0.000733 29 262 7 KEGG:00250 ke Alanine, aspartate and glutamate metabolism hap5 3.61e-05 17 262 7 REAC:504394 re Glycolysis hap5 9.13e-07 5 262 5 REAC:499691 re 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O hap5 0.000257 29 262 8 REAC:504367 re Purine metabolism hap5 5.21e-06 6 262 5 REAC:504411 re De novo synthesis of IMP hap5 2.73e-05 22 262 8 REAC:504355 re Gluconeogenesis hap5 9.13e-07 5 262 5 REAC:503441 re Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate hat2 5.76e-05 31 492 10 GO:0009066 BP aspartate family amino acid metabolic process hat2 3.44e-05 456 492 58 GO:0044281 BP small molecule metabolic process hat2 3.52e-05 131 492 24 GO:0044283 BP small molecule biosynthetic process hat2 2.57e-05 180 492 30 GO:0042180 BP cellular ketone metabolic process hat2 4.38e-05 176 492 29 GO:0006082 BP organic acid metabolic process hat2 4.38e-05 176 492 29 GO:0043436 BP oxoacid metabolic process hat2 4.38e-05 176 492 29 GO:0019752 BP carboxylic acid metabolic process hat2 1.89e-08 23 492 12 GO:0046165 BP alcohol biosynthetic process hat2 1.78e-05 39 492 12 GO:0034637 BP cellular carbohydrate biosynthetic process hat2 5.26e-05 78 492 17 GO:0005996 BP monosaccharide metabolic process hat2 1.18e-08 15 492 10 GO:0046364 BP monosaccharide biosynthetic process hat2 3.91e-05 69 492 16 GO:0019318 BP hexose metabolic process hat2 1.34e-08 12 492 9 GO:0019319 BP hexose biosynthetic process hat2 1.7e-05 58 492 15 GO:0006006 BP glucose metabolic process hat2 1.39e-07 18 492 10 GO:0006090 BP pyruvate metabolic process hat2 3.96e-08 10 492 8 GO:0006094 BP gluconeogenesis hat2 4.03e-09 89 492 25 GO:0030312 CC external encapsulating structure hat2 4.03e-09 89 492 25 GO:0005618 CC cell wall hat2 4.03e-09 89 492 25 GO:0009277 CC fungal-type cell wall hat2 3.5e-06 47 492 17 KEGG:00010 ke Glycolysis / Gluconeogenesis hat2 2.95e-06 142 492 34 KEGG:03010 ke Ribosome hat2 6.69e-06 22 492 11 REAC:504355 re Gluconeogenesis hat2 1.86e-05 5 492 5 REAC:503441 re Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate hat2 0.00015 65 492 18 REAC:504349 re Metabolism of carbohydrates hat2 0.000116 152 492 32 REAC:504522 re 3' -UTR-mediated translational regulation hat2 0.000116 152 492 32 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression hat2 0.000734 79 492 19 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit hat2 1.11e-08 17 492 12 REAC:504394 re Glycolysis hat2 1.86e-05 5 492 5 REAC:499691 re 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O hat2 0.000539 200 492 37 REAC:504343 re Metabolism of proteins hat2 8.97e-05 164 492 34 REAC:504507 re Translation hat2 5e-06 139 492 33 REAC:504506 re Eukaryotic Translation Elongation hat2 5e-06 139 492 33 REAC:504505 re Peptide chain elongation hat2 1.1e-05 137 492 32 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site hat2 1.1e-05 137 492 32 REAC:502806 re Hydrolysis of eEF1A:GTP hat2 2.38e-05 135 492 31 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA hat2 5e-06 139 492 33 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction hat2 3e-04 159 492 32 REAC:504612 re Eukaryotic Translation Initiation hat2 3e-04 159 492 32 REAC:504611 re Cap-dependent Translation Initiation hat2 2.81e-05 136 492 31 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit hat2 2.81e-05 136 492 31 REAC:504077 re The 60S subunit joins the translation initiation complex hat2 2.81e-05 136 492 31 REAC:502286 re eIF5B:GTP is hydrolyzed and released hat2 9.26e-06 136 492 32 REAC:504765 re Formation of a pool of free 40S subunits hat2 9.26e-06 136 492 32 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome hms1 1.05e-06 18 736 11 GO:0006090 BP pyruvate metabolic process hms1 3.14e-05 10 736 7 GO:0006094 BP gluconeogenesis hms1 2.66e-05 31 736 13 GO:0009066 BP aspartate family amino acid metabolic process hms1 2.41e-05 402 736 76 GO:0044429 CC mitochondrial part hms1 3.62e-09 89 736 32 GO:0030312 CC external encapsulating structure hms1 3.62e-09 89 736 32 GO:0005618 CC cell wall hms1 3.62e-09 89 736 32 GO:0009277 CC fungal-type cell wall hms1 0.000915 47 736 18 KEGG:00010 ke Glycolysis / Gluconeogenesis hms1 4.83e-22 142 736 74 KEGG:03010 ke Ribosome hms1 2.44e-17 152 736 72 REAC:504522 re 3' -UTR-mediated translational regulation hms1 2.44e-17 152 736 72 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression hms1 7.14e-12 79 736 42 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit hms1 4.4e-05 76 736 30 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA hms1 0.00049 17 736 10 REAC:504394 re Glycolysis hms1 0.000332 5 736 5 REAC:499691 re 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O hms1 0.00158 22 736 11 REAC:504355 re Gluconeogenesis hms1 0.000332 5 736 5 REAC:503441 re Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate hms1 3.18e-12 200 736 77 REAC:504343 re Metabolism of proteins hms1 5.11e-10 259 736 87 REAC:504459 re Gene Expression hms1 5.6e-15 164 736 72 REAC:504507 re Translation hms1 9.87e-19 139 736 70 REAC:504506 re Eukaryotic Translation Elongation hms1 9.87e-19 139 736 70 REAC:504505 re Peptide chain elongation hms1 3.27e-19 137 736 70 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site hms1 3.27e-19 137 736 70 REAC:502806 re Hydrolysis of eEF1A:GTP hms1 1.05e-19 135 736 70 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA hms1 9.87e-19 139 736 70 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction hms1 6.4e-16 159 736 72 REAC:504612 re Eukaryotic Translation Initiation hms1 6.4e-16 159 736 72 REAC:504611 re Cap-dependent Translation Initiation hms1 2.35e-05 74 736 30 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S hms1 2.35e-05 74 736 30 REAC:504671 re Translation initiation complex formation hms1 1.69e-05 73 736 30 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize hms1 2.35e-05 74 736 30 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation hms1 2.35e-05 74 736 30 REAC:504769 re Ribosomal scanning and start codon recognition hms1 1.69e-05 73 736 30 REAC:503952 re Ribosomal scanning hms1 2.35e-05 74 736 30 REAC:504040 re Start codon recognition hms1 1.92e-06 67 736 30 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex hms1 1.92e-06 67 736 30 REAC:502531 re Formation of the 43S pre-initiation complex hms1 1.86e-19 136 736 70 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit hms1 1.86e-19 136 736 70 REAC:504077 re The 60S subunit joins the translation initiation complex hms1 1.86e-19 136 736 70 REAC:502286 re eIF5B:GTP is hydrolyzed and released hms1 2.87e-20 136 736 71 REAC:504765 re Formation of a pool of free 40S subunits hms1 2.87e-20 136 736 71 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome hst3 4.88e-05 4 152 3 GO:0007157 BP heterophilic cell adhesion hst3 3.18e-05 215 152 16 GO:0019953 BP sexual reproduction hst3 5.92e-05 114 152 11 GO:0000746 BP conjugation hst3 4.88e-05 4 152 3 GO:0000771 BP agglutination involved in conjugation hst3 5.92e-05 114 152 11 GO:0000747 BP conjugation with cellular fusion hst3 3.87e-05 90 152 10 GO:0019236 BP response to pheromone hst3 2.64e-06 67 152 10 GO:0000749 BP response to pheromone during conjugation with cellular fusion hst3 4.88e-05 4 152 3 GO:0000752 BP agglutination involved in conjugation with cellular fusion hst3 4.55e-15 89 152 20 GO:0030312 CC external encapsulating structure hst3 4.55e-15 89 152 20 GO:0005618 CC cell wall hst3 4.55e-15 89 152 20 GO:0009277 CC fungal-type cell wall hst3 1.24e-05 3 152 3 GO:0050839 MF cell adhesion molecule binding hst3 8.2e-05 11 152 4 GO:0005199 MF structural constituent of cell wall hst3 0.00136 18 152 4 KEGG:00290 ke Valine, leucine and isoleucine biosynthesis hst3 0.000433 2 152 2 REAC:500635 re alpha-ketoglutarate + NH4+ + NADPH + H+ => glutamate + NADP+ hst3 0.000433 2 152 2 REAC:502958 re isoleucine + alpha-ketoglutarate <=> alpha-keto-beta-methylvalerate + glutamate [mitochondrial] hst3 0.000433 2 152 2 REAC:502635 re glutamate + NAD+ => alpha-ketoglutarate + NH4+ + NADH + H+ hst3 2.89e-05 49 152 7 REAC:504363 re Metabolism of amino acids hst3 0.000433 2 152 2 REAC:504704 re Neurotransmitter Release Cycle hst3 0.000433 2 152 2 REAC:504703 re Glutamate Neurotransmitter Release Cycle hst3 0.000433 2 152 2 REAC:504702 re Leucine catabolism hst3 0.000433 2 152 2 REAC:502986 re L-Glutamate [mitochondrial] from leucine catabolism hst3 0.000433 2 152 2 REAC:502985 re L-Glutamate [cytosolic] from leucine catabolism hst3 0.000433 2 152 2 REAC:504255 re valine + alpha-ketoglutarate <=> alpha-ketoisovalerate + glutamate [mitochondrial] hst3 0.000433 2 152 2 REAC:502952 re isoleucine + alpha-ketoglutarate <=> alpha-keto-beta-methylvalerate + glutamate [cytosolic] hst3 0.000433 2 152 2 REAC:504254 re valine + alpha-ketoglutarate <=> alpha-ketoisovalerate + glutamate [cytosolic] isw1 1.96e-06 131 432 25 GO:0044283 BP small molecule biosynthetic process isw1 1.04e-06 23 432 10 GO:0046165 BP alcohol biosynthetic process isw1 2.68e-05 15 432 7 GO:0046364 BP monosaccharide biosynthetic process isw1 3.96e-06 12 432 7 GO:0019319 BP hexose biosynthetic process isw1 8.5e-07 18 432 9 GO:0006090 BP pyruvate metabolic process isw1 6.77e-07 10 432 7 GO:0006094 BP gluconeogenesis isw1 1.04e-05 180 432 29 GO:0042180 BP cellular ketone metabolic process isw1 1.89e-05 176 432 28 GO:0006082 BP organic acid metabolic process isw1 1.89e-05 176 432 28 GO:0043436 BP oxoacid metabolic process isw1 1.89e-05 176 432 28 GO:0019752 BP carboxylic acid metabolic process isw1 1.53e-06 89 432 20 GO:0030312 CC external encapsulating structure isw1 1.53e-06 89 432 20 GO:0005618 CC cell wall isw1 1.53e-06 89 432 20 GO:0009277 CC fungal-type cell wall isw1 6e-06 142 432 32 KEGG:03010 ke Ribosome isw1 7.52e-05 200 432 34 REAC:504343 re Metabolism of proteins isw1 0.00031 259 432 39 REAC:504459 re Gene Expression isw1 1.84e-06 164 432 33 REAC:504507 re Translation isw1 9.17e-08 139 432 32 REAC:504506 re Eukaryotic Translation Elongation isw1 9.17e-08 139 432 32 REAC:504505 re Peptide chain elongation isw1 6.21e-08 137 432 32 REAC:502806 re Hydrolysis of eEF1A:GTP isw1 6.21e-08 137 432 32 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site isw1 1.75e-07 135 432 31 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA isw1 9.17e-08 139 432 32 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction isw1 2.91e-06 159 432 32 REAC:504612 re Eukaryotic Translation Initiation isw1 2.91e-06 159 432 32 REAC:504611 re Cap-dependent Translation Initiation isw1 2.12e-07 136 432 31 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit isw1 2.12e-07 136 432 31 REAC:504077 re The 60S subunit joins the translation initiation complex isw1 2.12e-07 136 432 31 REAC:502286 re eIF5B:GTP is hydrolyzed and released isw1 5.09e-08 136 432 32 REAC:504765 re Formation of a pool of free 40S subunits isw1 5.09e-08 136 432 32 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome isw1 0.000504 22 432 8 REAC:504355 re Gluconeogenesis isw1 0.000832 3 432 3 REAC:499530 re 1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+ isw1 0.000354 5 432 4 REAC:503441 re Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate isw1 5.35e-06 17 432 9 REAC:504394 re Glycolysis isw1 0.000354 5 432 4 REAC:499691 re 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O isw1 0.000832 3 432 3 REAC:504608 re Glyceraldehyde 3-phosphate, NAD+, and orthophosphate react to form 1,3-bisphosphoglycerate, NADH, and H+ isw1 0.000832 3 432 3 REAC:501949 re D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ isw1 9.47e-07 152 432 32 REAC:504522 re 3' -UTR-mediated translational regulation isw1 9.47e-07 152 432 32 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression isw1 4.49e-05 79 432 19 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit isw2 1.56e-05 23 1209 14 GO:0046165 BP alcohol biosynthetic process isw2 1.57e-07 18 1209 14 GO:0006090 BP pyruvate metabolic process isw2 1.32e-06 89 1209 37 GO:0030312 CC external encapsulating structure isw2 1.32e-06 89 1209 37 GO:0005618 CC cell wall isw2 1.32e-06 89 1209 37 GO:0009277 CC fungal-type cell wall isw2 7.28e-07 11 1209 10 GO:0000786 CC nucleosome isw2 7.28e-07 11 1209 10 GO:0000788 CC nuclear nucleosome isw2 3.98e-06 47 1209 27 KEGG:00010 ke Glycolysis / Gluconeogenesis isw2 7.16e-20 142 1209 86 KEGG:03010 ke Ribosome isw2 2.16e-16 152 1209 86 REAC:504522 re 3' -UTR-mediated translational regulation isw2 2.16e-16 152 1209 86 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression isw2 8.47e-10 79 1209 47 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit isw2 6.05e-07 76 1209 41 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA isw2 1.23e-12 200 1209 97 REAC:504343 re Metabolism of proteins isw2 3.47e-09 259 1209 109 REAC:504459 re Gene Expression isw2 8.62e-15 164 1209 88 REAC:504507 re Translation isw2 1.5e-18 139 1209 84 REAC:504506 re Eukaryotic Translation Elongation isw2 1.5e-18 139 1209 84 REAC:504505 re Peptide chain elongation isw2 2.1e-18 137 1209 83 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site isw2 2.1e-18 137 1209 83 REAC:502806 re Hydrolysis of eEF1A:GTP isw2 2.95e-18 135 1209 82 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA isw2 1.5e-18 139 1209 84 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction isw2 1.07e-14 159 1209 86 REAC:504612 re Eukaryotic Translation Initiation isw2 1.07e-14 159 1209 86 REAC:504611 re Cap-dependent Translation Initiation isw2 7.96e-07 74 1209 40 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S isw2 7.96e-07 74 1209 40 REAC:504671 re Translation initiation complex formation isw2 1.69e-06 73 1209 39 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize isw2 7.96e-07 74 1209 40 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation isw2 2.68e-06 74 1209 39 REAC:504769 re Ribosomal scanning and start codon recognition isw2 1.69e-06 73 1209 39 REAC:503952 re Ribosomal scanning isw2 2.68e-06 74 1209 39 REAC:504040 re Start codon recognition isw2 2.93e-07 67 1209 38 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex isw2 2.93e-07 67 1209 38 REAC:502531 re Formation of the 43S pre-initiation complex isw2 5.82e-18 136 1209 82 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit isw2 5.82e-18 136 1209 82 REAC:504077 re The 60S subunit joins the translation initiation complex isw2 5.82e-18 136 1209 82 REAC:502286 re eIF5B:GTP is hydrolyzed and released isw2 1.06e-18 136 1209 83 REAC:504765 re Formation of a pool of free 40S subunits isw2 1.06e-18 136 1209 83 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome kar4 5.04e-05 6 288 4 GO:0009081 BP branched chain family amino acid metabolic process kar4 9.21e-06 128 288 18 GO:0051704 BP multi-organism process kar4 1.68e-06 114 288 18 GO:0000746 BP conjugation kar4 1.68e-06 114 288 18 GO:0000747 BP conjugation with cellular fusion kar4 6.45e-06 90 288 15 GO:0019236 BP response to pheromone kar4 2.64e-05 67 288 12 GO:0000749 BP response to pheromone during conjugation with cellular fusion kar4 1.1e-06 89 288 16 GO:0030312 CC external encapsulating structure kar4 1.1e-06 89 288 16 GO:0005618 CC cell wall kar4 1.1e-06 89 288 16 GO:0009277 CC fungal-type cell wall kar4 5.77e-05 11 288 5 GO:0005199 MF structural constituent of cell wall kar4 8.32e-05 3 288 3 GO:0050839 MF cell adhesion molecule binding kar4 0.000371 10 288 5 KEGG:00280 ke Valine, leucine and isoleucine degradation kar4 0.00155 8 288 4 KEGG:00980 ke Metabolism of xenobiotics by cytochrome P450 kar4 5.6e-12 142 288 35 KEGG:03010 ke Ribosome kar4 0.000486 73 288 14 REAC:503952 re Ribosomal scanning kar4 3.01e-09 200 288 36 REAC:504343 re Metabolism of proteins kar4 4.42e-07 259 288 38 REAC:504459 re Gene Expression kar4 1.82e-10 164 288 34 REAC:504507 re Translation kar4 6.49e-12 139 288 33 REAC:504506 re Eukaryotic Translation Elongation kar4 6.49e-12 139 288 33 REAC:504505 re Peptide chain elongation kar4 4.09e-12 137 288 33 REAC:502806 re Hydrolysis of eEF1A:GTP kar4 4.09e-12 137 288 33 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site kar4 1.81e-11 135 288 32 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA kar4 6.49e-12 139 288 33 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction kar4 4.11e-10 159 288 33 REAC:504612 re Eukaryotic Translation Initiation kar4 4.11e-10 159 288 33 REAC:504611 re Cap-dependent Translation Initiation kar4 0.000184 67 288 14 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex kar4 0.000184 67 288 14 REAC:502531 re Formation of the 43S pre-initiation complex kar4 2.27e-11 136 288 32 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit kar4 2.27e-11 136 288 32 REAC:504077 re The 60S subunit joins the translation initiation complex kar4 2.27e-11 136 288 32 REAC:502286 re eIF5B:GTP is hydrolyzed and released kar4 3.24e-12 136 288 33 REAC:504765 re Formation of a pool of free 40S subunits kar4 3.24e-12 136 288 33 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome kar4 0.000486 73 288 14 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize kar4 1.05e-10 152 288 33 REAC:504522 re 3' -UTR-mediated translational regulation kar4 1.05e-10 152 288 33 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression kar4 8.59e-07 79 288 19 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit phd1 4.68e-05 6 277 4 GO:0009081 BP branched chain family amino acid metabolic process phd1 3.81e-07 128 277 20 GO:0051704 BP multi-organism process phd1 5.23e-08 114 277 20 GO:0000746 BP conjugation phd1 3.94e-05 215 277 23 GO:0019953 BP sexual reproduction phd1 5.23e-08 114 277 20 GO:0000747 BP conjugation with cellular fusion phd1 1.81e-07 90 277 17 GO:0019236 BP response to pheromone phd1 3.9e-06 67 277 13 GO:0000749 BP response to pheromone during conjugation with cellular fusion phd1 1.12e-12 89 277 23 GO:0030312 CC external encapsulating structure phd1 1.12e-12 89 277 23 GO:0005618 CC cell wall phd1 1.12e-12 89 277 23 GO:0009277 CC fungal-type cell wall phd1 2.29e-06 11 277 6 GO:0005199 MF structural constituent of cell wall phd1 7.87e-05 3 277 3 GO:0050839 MF cell adhesion molecule binding phd1 4.1e-05 142 277 22 KEGG:03010 ke Ribosome phd1 0.000193 10 277 5 KEGG:00280 ke Valine, leucine and isoleucine degradation phd1 6.7e-06 152 277 22 REAC:504522 re 3' -UTR-mediated translational regulation phd1 6.7e-06 152 277 22 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression phd1 6.19e-05 79 277 14 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit phd1 1.79e-05 200 277 25 REAC:504343 re Metabolism of proteins phd1 0.000233 259 277 27 REAC:504459 re Gene Expression phd1 6.39e-06 164 277 23 REAC:504507 re Translation phd1 1.3e-06 139 277 22 REAC:504506 re Eukaryotic Translation Elongation phd1 1.3e-06 139 277 22 REAC:504505 re Peptide chain elongation phd1 9.86e-07 137 277 22 REAC:502806 re Hydrolysis of eEF1A:GTP phd1 9.86e-07 137 277 22 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site phd1 3.57e-06 135 277 21 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA phd1 1.3e-06 139 277 22 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction phd1 1.49e-05 159 277 22 REAC:504612 re Eukaryotic Translation Initiation phd1 1.49e-05 159 277 22 REAC:504611 re Cap-dependent Translation Initiation phd1 4.07e-06 136 277 21 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit phd1 4.07e-06 136 277 21 REAC:504077 re The 60S subunit joins the translation initiation complex phd1 4.07e-06 136 277 21 REAC:502286 re eIF5B:GTP is hydrolyzed and released phd1 4.07e-06 136 277 21 REAC:504765 re Formation of a pool of free 40S subunits phd1 4.07e-06 136 277 21 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome pip2 6.37e-06 18 1088 12 GO:0006090 BP pyruvate metabolic process pip2 5.57e-07 221 1088 69 GO:0005783 CC endoplasmic reticulum pip2 1.68e-05 37 1088 18 GO:0005732 CC small nucleolar ribonucleoprotein complex pip2 1.17e-07 89 1088 37 GO:0030312 CC external encapsulating structure pip2 1.17e-07 89 1088 37 GO:0005618 CC cell wall pip2 1.17e-07 89 1088 37 GO:0009277 CC fungal-type cell wall pip2 1.63e-05 47 1088 25 KEGG:00010 ke Glycolysis / Gluconeogenesis pip2 1.1e-23 142 1088 88 KEGG:03010 ke Ribosome pip2 6.38e-22 152 1088 90 REAC:504522 re 3' -UTR-mediated translational regulation pip2 6.38e-22 152 1088 90 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression pip2 4.94e-14 79 1088 51 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit pip2 2.4e-07 76 1088 40 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA pip2 2.02e-16 200 1088 99 REAC:504343 re Metabolism of proteins pip2 9.41e-13 259 1088 111 REAC:504459 re Gene Expression pip2 2.38e-19 164 1088 91 REAC:504507 re Translation pip2 1.49e-23 139 1088 87 REAC:504506 re Eukaryotic Translation Elongation pip2 1.49e-23 139 1088 87 REAC:504505 re Peptide chain elongation pip2 3.12e-24 137 1088 87 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site pip2 3.12e-24 137 1088 87 REAC:502806 re Hydrolysis of eEF1A:GTP pip2 4.7e-24 135 1088 86 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA pip2 1.49e-23 139 1088 87 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction pip2 6.12e-20 159 1088 90 REAC:504612 re Eukaryotic Translation Initiation pip2 6.12e-20 159 1088 90 REAC:504611 re Cap-dependent Translation Initiation pip2 3.34e-07 74 1088 39 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pip2 3.34e-07 74 1088 39 REAC:504671 re Translation initiation complex formation pip2 2.05e-07 73 1088 39 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize pip2 3.34e-07 74 1088 39 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation pip2 3.34e-07 74 1088 39 REAC:504769 re Ribosomal scanning and start codon recognition pip2 2.05e-07 73 1088 39 REAC:503952 re Ribosomal scanning pip2 3.34e-07 74 1088 39 REAC:504040 re Start codon recognition pip2 3.39e-08 67 1088 38 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex pip2 3.39e-08 67 1088 38 REAC:502531 re Formation of the 43S pre-initiation complex pip2 1.04e-23 136 1088 86 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit pip2 1.04e-23 136 1088 86 REAC:504077 re The 60S subunit joins the translation initiation complex pip2 1.04e-23 136 1088 86 REAC:502286 re eIF5B:GTP is hydrolyzed and released pip2 1.4e-24 136 1088 87 REAC:504765 re Formation of a pool of free 40S subunits pip2 1.4e-24 136 1088 87 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome put3 1.05e-05 131 446 24 GO:0044283 BP small molecule biosynthetic process put3 5.73e-13 89 446 29 GO:0030312 CC external encapsulating structure put3 5.73e-13 89 446 29 GO:0005618 CC cell wall put3 5.73e-13 89 446 29 GO:0009277 CC fungal-type cell wall put3 2.16e-07 142 446 35 KEGG:03010 ke Ribosome put3 0.000505 8 446 5 KEGG:00980 ke Metabolism of xenobiotics by cytochrome P450 put3 0.00191 10 446 5 KEGG:00280 ke Valine, leucine and isoleucine degradation put3 0.000641 47 446 13 KEGG:00010 ke Glycolysis / Gluconeogenesis put3 2.73e-06 152 446 34 REAC:504522 re 3' -UTR-mediated translational regulation put3 2.73e-06 152 446 34 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression put3 9.18e-05 79 446 20 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit put3 1.54e-05 200 446 39 REAC:504343 re Metabolism of proteins put3 0.000152 259 446 44 REAC:504459 re Gene Expression put3 6.09e-06 164 446 35 REAC:504507 re Translation put3 2.5e-07 139 446 34 REAC:504506 re Eukaryotic Translation Elongation put3 2.5e-07 139 446 34 REAC:504505 re Peptide chain elongation put3 1.67e-07 137 446 34 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site put3 1.67e-07 137 446 34 REAC:502806 re Hydrolysis of eEF1A:GTP put3 4.21e-07 135 446 33 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA put3 2.5e-07 139 446 34 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction put3 8.55e-06 159 446 34 REAC:504612 re Eukaryotic Translation Initiation put3 8.55e-06 159 446 34 REAC:504611 re Cap-dependent Translation Initiation put3 5.12e-07 136 446 33 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit put3 5.12e-07 136 446 33 REAC:504077 re The 60S subunit joins the translation initiation complex put3 5.12e-07 136 446 33 REAC:502286 re eIF5B:GTP is hydrolyzed and released put3 1.36e-07 136 446 34 REAC:504765 re Formation of a pool of free 40S subunits put3 1.36e-07 136 446 34 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome rds2 4.88e-06 23 383 9 GO:0046165 BP alcohol biosynthetic process rds2 1.46e-05 15 383 7 GO:0046364 BP monosaccharide biosynthetic process rds2 2.11e-06 12 383 7 GO:0019319 BP hexose biosynthetic process rds2 5.39e-06 18 383 8 GO:0006090 BP pyruvate metabolic process rds2 9.67e-06 10 383 6 GO:0006094 BP gluconeogenesis rds2 1.01e-11 89 383 26 GO:0030312 CC external encapsulating structure rds2 1.01e-11 89 383 26 GO:0005618 CC cell wall rds2 1.01e-11 89 383 26 GO:0009277 CC fungal-type cell wall rds2 9.29e-07 11 383 7 GO:0005199 MF structural constituent of cell wall rds2 0.000528 47 383 13 KEGG:00010 ke Glycolysis / Gluconeogenesis rds2 6.7e-18 142 383 50 KEGG:03010 ke Ribosome rds2 6.74e-06 17 383 10 REAC:504394 re Glycolysis rds2 3.07e-05 5 383 5 REAC:499691 re 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O rds2 1.55e-11 152 383 47 REAC:504522 re 3' -UTR-mediated translational regulation rds2 1.55e-11 152 383 47 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression rds2 5.94e-09 79 383 29 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit rds2 1.4e-09 200 383 52 REAC:504343 re Metabolism of proteins rds2 1.71e-08 259 383 59 REAC:504459 re Gene Expression rds2 1.9e-11 164 383 49 REAC:504507 re Translation rds2 5.46e-14 139 383 48 REAC:504506 re Eukaryotic Translation Elongation rds2 5.46e-14 139 383 48 REAC:504505 re Peptide chain elongation rds2 2.76e-14 137 383 48 REAC:502806 re Hydrolysis of eEF1A:GTP rds2 2.76e-14 137 383 48 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site rds2 4.62e-13 135 383 46 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA rds2 5.46e-14 139 383 48 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction rds2 1.03e-10 159 383 47 REAC:504612 re Eukaryotic Translation Initiation rds2 1.03e-10 159 383 47 REAC:504611 re Cap-dependent Translation Initiation rds2 6.39e-13 136 383 46 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit rds2 6.39e-13 136 383 46 REAC:504077 re The 60S subunit joins the translation initiation complex rds2 6.39e-13 136 383 46 REAC:502286 re eIF5B:GTP is hydrolyzed and released rds2 1.15e-13 136 383 47 REAC:504765 re Formation of a pool of free 40S subunits rds2 1.15e-13 136 383 47 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome rds2 0.000128 22 383 10 REAC:504355 re Gluconeogenesis rds2 3.07e-05 5 383 5 REAC:503441 re Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate rgt1 3.54e-05 180 398 26 GO:0042180 BP cellular ketone metabolic process rgt1 6.67e-05 176 398 25 GO:0006082 BP organic acid metabolic process rgt1 6.67e-05 176 398 25 GO:0043436 BP oxoacid metabolic process rgt1 6.67e-05 176 398 25 GO:0019752 BP carboxylic acid metabolic process rgt1 1.33e-05 131 398 22 GO:0044283 BP small molecule biosynthetic process rgt1 3.99e-07 23 398 10 GO:0046165 BP alcohol biosynthetic process rgt1 8.68e-07 15 398 8 GO:0046364 BP monosaccharide biosynthetic process rgt1 1.98e-06 12 398 7 GO:0019319 BP hexose biosynthetic process rgt1 5.73e-05 18 398 7 GO:0006090 BP pyruvate metabolic process rgt1 9.13e-06 10 398 6 GO:0006094 BP gluconeogenesis rgt1 3.4e-10 89 398 24 GO:0030312 CC external encapsulating structure rgt1 3.4e-10 89 398 24 GO:0005618 CC cell wall rgt1 3.4e-10 89 398 24 GO:0009277 CC fungal-type cell wall rgt1 2e-05 47 398 15 KEGG:00010 ke Glycolysis / Gluconeogenesis rgt1 0.000129 10 398 6 KEGG:00280 ke Valine, leucine and isoleucine degradation rgt1 5.27e-05 142 398 29 KEGG:03010 ke Ribosome rgt1 0.000102 152 398 29 REAC:504522 re 3' -UTR-mediated translational regulation rgt1 0.000102 152 398 29 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression rgt1 1.4e-05 22 398 10 REAC:504355 re Gluconeogenesis rgt1 8.91e-06 5 398 5 REAC:503441 re Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate rgt1 0.000605 200 398 33 REAC:504343 re Metabolism of proteins rgt1 0.000172 164 398 30 REAC:504507 re Translation rgt1 0.000142 139 398 27 REAC:504506 re Eukaryotic Translation Elongation rgt1 0.000142 139 398 27 REAC:504505 re Peptide chain elongation rgt1 0.000108 137 398 27 REAC:502806 re Hydrolysis of eEF1A:GTP rgt1 0.000108 137 398 27 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site rgt1 0.000232 135 398 26 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA rgt1 0.000142 139 398 27 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction rgt1 0.000248 159 398 29 REAC:504612 re Eukaryotic Translation Initiation rgt1 0.000248 159 398 29 REAC:504611 re Cap-dependent Translation Initiation rgt1 0.000265 136 398 26 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit rgt1 0.000265 136 398 26 REAC:504077 re The 60S subunit joins the translation initiation complex rgt1 0.000265 136 398 26 REAC:502286 re eIF5B:GTP is hydrolyzed and released rgt1 9.36e-05 136 398 27 REAC:504765 re Formation of a pool of free 40S subunits rgt1 9.36e-05 136 398 27 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome rgt1 6.43e-07 17 398 10 REAC:504394 re Glycolysis rgt1 8.91e-06 5 398 5 REAC:499691 re 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O ris1 2.38e-05 31 707 13 GO:0009066 BP aspartate family amino acid metabolic process ris1 4.14e-06 180 707 43 GO:0042180 BP cellular ketone metabolic process ris1 5.53e-06 176 707 42 GO:0006082 BP organic acid metabolic process ris1 5.53e-06 176 707 42 GO:0043436 BP oxoacid metabolic process ris1 5.53e-06 176 707 42 GO:0019752 BP carboxylic acid metabolic process ris1 1.28e-05 12 707 8 GO:0019319 BP hexose biosynthetic process ris1 7.24e-08 18 707 12 GO:0006090 BP pyruvate metabolic process ris1 2.93e-05 10 707 7 GO:0006094 BP gluconeogenesis ris1 2.98e-06 23 707 12 GO:0046165 BP alcohol biosynthetic process ris1 3.62e-07 63 707 23 GO:0070085 BP glycosylation ris1 3.62e-07 63 707 23 GO:0043413 BP macromolecule glycosylation ris1 2.3e-06 69 707 23 GO:0009100 BP glycoprotein metabolic process ris1 1.72e-06 68 707 23 GO:0009101 BP glycoprotein biosynthetic process ris1 6.52e-08 173 707 46 GO:0044262 BP cellular carbohydrate metabolic process ris1 3.62e-07 63 707 23 GO:0006486 BP protein amino acid glycosylation ris1 2.71e-07 45 707 19 GO:0006487 BP protein amino acid N-linked glycosylation ris1 5.22e-06 53 707 19 GO:0016051 BP carbohydrate biosynthetic process ris1 9.43e-06 3636 707 477 GO:0005575 CC cellular_component ris1 6.56e-06 3629 707 477 GO:0005623 CC cell ris1 6.22e-06 3628 707 477 GO:0044464 CC cell part ris1 2.7e-14 89 707 39 GO:0030312 CC external encapsulating structure ris1 2.7e-14 89 707 39 GO:0005618 CC cell wall ris1 2.7e-14 89 707 39 GO:0009277 CC fungal-type cell wall ris1 7.23e-05 11 707 7 GO:0005199 MF structural constituent of cell wall ris1 0.000194 29 707 13 KEGG:00510 ke N-Glycan biosynthesis ris1 0.00184 10 707 6 KEGG:00280 ke Valine, leucine and isoleucine degradation ris1 0.00174 13 707 7 KEGG:00300 ke Lysine biosynthesis ris1 0.000307 23 707 11 KEGG:00260 ke Glycine, serine and threonine metabolism ris1 5.06e-07 616 707 133 KEGG:01100 ke Metabolic pathways ris1 1.99e-06 47 707 21 KEGG:00010 ke Glycolysis / Gluconeogenesis ris1 0.000253 49 707 18 REAC:504363 re Metabolism of amino acids ris1 0.000199 65 707 22 REAC:504349 re Metabolism of carbohydrates ris1 6.81e-05 45 707 18 REAC:504348 re Glucose metabolism ris1 3.07e-05 22 707 12 REAC:504355 re Gluconeogenesis ris1 0.000104 5 707 5 REAC:503441 re Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate ris1 2.42e-06 71 707 27 REAC:504353 re Integration of energy metabolism ris1 1.21e-05 48 707 20 REAC:504354 re Diabetes pathways ris1 1.21e-05 48 707 20 REAC:504352 re Glucose Regulation of Insulin Secretion ris1 7.08e-06 17 707 11 REAC:504394 re Glycolysis ris1 0.000104 5 707 5 REAC:499691 re 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O rpd3 1.19e-05 128 98 10 GO:0051704 BP multi-organism process rpd3 4.19e-06 114 98 10 GO:0000746 BP conjugation rpd3 8.94e-06 215 98 13 GO:0019953 BP sexual reproduction rpd3 4.19e-06 114 98 10 GO:0000747 BP conjugation with cellular fusion rpd3 4.1e-05 28 98 5 GO:0032005 BP signal transduction involved in conjugation with cellular fusion rpd3 7.43e-05 158 98 10 GO:0010033 BP response to organic substance rpd3 4.63e-07 90 98 10 GO:0019236 BP response to pheromone rpd3 3.52e-07 67 98 9 GO:0000749 BP response to pheromone during conjugation with cellular fusion rpd3 2.81e-05 5 98 3 GO:0016337 BP cell-cell adhesion rpd3 1.14e-05 4 98 3 GO:0007157 BP heterophilic cell adhesion rpd3 1.14e-05 4 98 3 GO:0000771 BP agglutination involved in conjugation rpd3 1.14e-05 4 98 3 GO:0000752 BP agglutination involved in conjugation with cellular fusion rpd3 6.86e-05 31 98 5 GO:0007186 BP G-protein coupled receptor protein signaling pathway rpd3 4.1e-05 28 98 5 GO:0000750 BP pheromone-dependent signal transduction involved in conjugation with cellular fusion rpd3 2.87e-06 3 98 3 GO:0050839 MF cell adhesion molecule binding rpd3 0.00171 55 98 5 KEGG:04011 ke MAPK signaling pathway - yeast rpd3 0.000461 10 98 3 KEGG:00280 ke Valine, leucine and isoleucine degradation rpd3 0.00016 18 98 4 KEGG:00290 ke Valine, leucine and isoleucine biosynthesis rpd3 0.000156 2 98 2 REAC:504255 re valine + alpha-ketoglutarate <=> alpha-ketoisovalerate + glutamate [mitochondrial] rpd3 0.000156 2 98 2 REAC:502958 re isoleucine + alpha-ketoglutarate <=> alpha-keto-beta-methylvalerate + glutamate [mitochondrial] rpd3 0.000156 2 98 2 REAC:502952 re isoleucine + alpha-ketoglutarate <=> alpha-keto-beta-methylvalerate + glutamate [cytosolic] rpd3 0.000156 2 98 2 REAC:504702 re Leucine catabolism rpd3 9.02e-05 8 98 3 REAC:504416 re Synaptic Transmission rpd3 9.02e-05 8 98 3 REAC:504415 re Transmission across Chemical Synapses rpd3 0.000156 2 98 2 REAC:504704 re Neurotransmitter Release Cycle rpd3 0.000156 2 98 2 REAC:504703 re Glutamate Neurotransmitter Release Cycle rpd3 0.000156 2 98 2 REAC:502986 re L-Glutamate [mitochondrial] from leucine catabolism rpd3 0.000156 2 98 2 REAC:502985 re L-Glutamate [cytosolic] from leucine catabolism rpd3 0.000156 2 98 2 REAC:504254 re valine + alpha-ketoglutarate <=> alpha-ketoisovalerate + glutamate [cytosolic] rtt107 2.23e-05 456 513 61 GO:0044281 BP small molecule metabolic process rtt107 1.02e-05 180 513 32 GO:0042180 BP cellular ketone metabolic process rtt107 1.71e-05 176 513 31 GO:0006082 BP organic acid metabolic process rtt107 1.71e-05 176 513 31 GO:0043436 BP oxoacid metabolic process rtt107 1.71e-05 176 513 31 GO:0019752 BP carboxylic acid metabolic process rtt107 3.56e-05 23 513 9 GO:0046165 BP alcohol biosynthetic process rtt107 7.16e-05 15 513 7 GO:0046364 BP monosaccharide biosynthetic process rtt107 1.09e-05 12 513 7 GO:0019319 BP hexose biosynthetic process rtt107 3.96e-05 10 513 6 GO:0006094 BP gluconeogenesis rtt107 4.48e-10 89 513 27 GO:0030312 CC external encapsulating structure rtt107 4.48e-10 89 513 27 GO:0005618 CC cell wall rtt107 4.48e-10 89 513 27 GO:0009277 CC fungal-type cell wall rtt107 0.000953 142 513 29 KEGG:03010 ke Ribosome rtt107 0.000507 47 513 14 KEGG:00010 ke Glycolysis / Gluconeogenesis rtt107 0.00068 19 513 8 KEGG:00450 ke Selenoamino acid metabolism rtt107 0.000197 29 513 11 KEGG:00270 ke Cysteine and methionine metabolism rtt107 1.94e-06 17 513 10 REAC:504394 re Glycolysis rtt107 0.000673 5 513 4 REAC:499691 re 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O rtt107 0.000394 152 513 30 REAC:504522 re 3' -UTR-mediated translational regulation rtt107 0.000394 152 513 30 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression rtt107 0.000703 164 513 31 REAC:504507 re Translation rtt107 0.000272 22 513 9 REAC:504355 re Gluconeogenesis rtt107 0.000673 5 513 4 REAC:503441 re Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate skn7 9.12e-05 12 274 5 GO:0019319 BP hexose biosynthetic process skn7 1.15e-11 89 274 22 GO:0030312 CC external encapsulating structure skn7 1.15e-11 89 274 22 GO:0005618 CC cell wall skn7 1.15e-11 89 274 22 GO:0009277 CC fungal-type cell wall skn7 8.34e-06 13 274 6 GO:0016705 MF oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen skn7 4.86e-05 6 274 4 GO:0051920 MF peroxiredoxin activity skn7 4.86e-05 6 274 4 GO:0008379 MF thioredoxin peroxidase activity skn7 5.51e-05 11 274 5 GO:0005199 MF structural constituent of cell wall skn7 0.00124 142 274 19 KEGG:03010 ke Ribosome skn7 0.00188 29 274 7 KEGG:00270 ke Cysteine and methionine metabolism skn7 0.000281 3 274 3 REAC:504608 re Glyceraldehyde 3-phosphate, NAD+, and orthophosphate react to form 1,3-bisphosphoglycerate, NADH, and H+ skn7 0.000281 3 274 3 REAC:501949 re D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ skn7 0.000281 3 274 3 REAC:499530 re 1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+ spt3 5.07e-06 131 1221 47 GO:0044283 BP small molecule biosynthetic process spt3 1.49e-05 18 1221 12 GO:0006090 BP pyruvate metabolic process spt3 2.41e-11 89 1221 45 GO:0030312 CC external encapsulating structure spt3 2.41e-11 89 1221 45 GO:0005618 CC cell wall spt3 2.41e-11 89 1221 45 GO:0009277 CC fungal-type cell wall stb5 7.19e-05 23 420 8 GO:0006643 BP membrane lipid metabolic process stb5 7.19e-05 23 420 8 GO:0006665 BP sphingolipid metabolic process stb5 1.52e-08 456 420 62 GO:0044281 BP small molecule metabolic process stb5 7.78e-08 131 420 27 GO:0044283 BP small molecule biosynthetic process stb5 2.75e-10 180 420 37 GO:0042180 BP cellular ketone metabolic process stb5 5.66e-10 176 420 36 GO:0006082 BP organic acid metabolic process stb5 5.66e-10 176 420 36 GO:0043436 BP oxoacid metabolic process stb5 5.66e-10 176 420 36 GO:0019752 BP carboxylic acid metabolic process stb5 4.43e-07 125 420 25 GO:0006519 BP cellular amino acid and derivative metabolic process stb5 7.86e-07 23 420 10 GO:0046165 BP alcohol biosynthetic process stb5 2.79e-08 193 420 35 GO:0034641 BP cellular nitrogen compound metabolic process stb5 1.2e-05 247 420 35 GO:0009308 BP amine metabolic process stb5 9.4e-07 113 420 23 GO:0044106 BP cellular amine metabolic process stb5 2.73e-07 98 420 22 GO:0006520 BP cellular amino acid metabolic process stb5 2.77e-08 31 420 13 GO:0009066 BP aspartate family amino acid metabolic process stb5 2.2e-05 15 420 7 GO:0046364 BP monosaccharide biosynthetic process stb5 5.47e-05 12 420 6 GO:0019319 BP hexose biosynthetic process stb5 8.63e-06 18 420 8 GO:0006090 BP pyruvate metabolic process stb5 1.77e-05 58 420 14 GO:0006006 BP glucose metabolic process stb5 1.39e-05 10 420 6 GO:0006094 BP gluconeogenesis stb5 4.29e-11 89 420 26 GO:0030312 CC external encapsulating structure stb5 4.29e-11 89 420 26 GO:0005618 CC cell wall stb5 4.29e-11 89 420 26 GO:0009277 CC fungal-type cell wall stb5 0.000412 23 420 9 KEGG:00260 ke Glycine, serine and threonine metabolism stb5 0.000642 29 420 10 KEGG:00270 ke Cysteine and methionine metabolism stb5 3.5e-06 47 420 17 KEGG:00010 ke Glycolysis / Gluconeogenesis stb5 9.57e-05 616 420 91 KEGG:01100 ke Metabolic pathways stb5 0.000356 49 420 13 REAC:504363 re Metabolism of amino acids stb5 1.06e-05 65 420 18 REAC:504349 re Metabolism of carbohydrates stb5 0.000137 45 420 13 REAC:504348 re Glucose metabolism stb5 9.94e-06 22 420 10 REAC:504355 re Gluconeogenesis stb5 7.4e-06 5 420 5 REAC:503441 re Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate stb5 0.000157 71 420 17 REAC:504353 re Integration of energy metabolism stb5 1.31e-05 48 420 15 REAC:504354 re Diabetes pathways stb5 1.31e-05 48 420 15 REAC:504352 re Glucose Regulation of Insulin Secretion stb5 5.96e-06 17 420 9 REAC:504394 re Glycolysis stb5 7.4e-06 5 420 5 REAC:499691 re 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O swi5 1.88e-07 180 295 26 GO:0042180 BP cellular ketone metabolic process swi5 4.57e-07 176 295 25 GO:0006082 BP organic acid metabolic process swi5 4.57e-07 176 295 25 GO:0043436 BP oxoacid metabolic process swi5 4.57e-07 176 295 25 GO:0019752 BP carboxylic acid metabolic process swi5 1.37e-05 79 295 14 GO:0032787 BP monocarboxylic acid metabolic process swi5 3.16e-08 18 295 9 GO:0006090 BP pyruvate metabolic process swi5 1.19e-07 131 295 22 GO:0044283 BP small molecule biosynthetic process swi5 2.84e-08 23 295 10 GO:0046165 BP alcohol biosynthetic process swi5 5.8e-05 39 295 9 GO:0034637 BP cellular carbohydrate biosynthetic process swi5 1.01e-07 15 295 8 GO:0046364 BP monosaccharide biosynthetic process swi5 8.75e-09 12 295 8 GO:0019319 BP hexose biosynthetic process swi5 4.86e-08 10 295 7 GO:0006094 BP gluconeogenesis swi5 6.28e-05 90 295 14 GO:0019236 BP response to pheromone swi5 6.86e-05 114 295 16 GO:0000746 BP conjugation swi5 6.86e-05 114 295 16 GO:0000747 BP conjugation with cellular fusion swi5 9.64e-08 89 295 18 GO:0030312 CC external encapsulating structure swi5 9.64e-08 89 295 18 GO:0005618 CC cell wall swi5 9.64e-08 89 295 18 GO:0009277 CC fungal-type cell wall swi5 7.63e-05 47 295 13 KEGG:00010 ke Glycolysis / Gluconeogenesis swi5 4.8e-12 142 295 38 KEGG:03010 ke Ribosome swi5 2.75e-10 152 295 37 REAC:504522 re 3' -UTR-mediated translational regulation swi5 2.75e-10 152 295 37 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression swi5 6.76e-08 79 295 23 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit swi5 6.18e-09 200 295 41 REAC:504343 re Metabolism of proteins swi5 2.08e-07 259 295 45 REAC:504459 re Gene Expression swi5 1.39e-10 164 295 39 REAC:504507 re Translation swi5 1.31e-11 139 295 37 REAC:504506 re Eukaryotic Translation Elongation swi5 1.31e-11 139 295 37 REAC:504505 re Peptide chain elongation swi5 7.91e-12 137 295 37 REAC:502806 re Hydrolysis of eEF1A:GTP swi5 7.91e-12 137 295 37 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site swi5 2.83e-11 135 295 36 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA swi5 1.31e-11 139 295 37 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction swi5 2.44e-10 159 295 38 REAC:504612 re Eukaryotic Translation Initiation swi5 2.44e-10 159 295 38 REAC:504611 re Cap-dependent Translation Initiation swi5 3.62e-11 136 295 36 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit swi5 3.62e-11 136 295 36 REAC:504077 re The 60S subunit joins the translation initiation complex swi5 3.62e-11 136 295 36 REAC:502286 re eIF5B:GTP is hydrolyzed and released swi5 6.12e-12 136 295 37 REAC:504765 re Formation of a pool of free 40S subunits swi5 6.12e-12 136 295 37 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome swi5 0.000407 45 295 12 REAC:504348 re Glucose metabolism swi5 6.95e-06 22 295 10 REAC:504355 re Gluconeogenesis swi5 0.00032 5 295 4 REAC:503441 re Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate swi5 3.08e-07 17 295 10 REAC:504394 re Glycolysis swi5 0.00032 5 295 4 REAC:499691 re 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O taf14 7.36e-05 12 912 8 GO:0019319 BP hexose biosynthetic process taf14 1e-05 18 912 11 GO:0006090 BP pyruvate metabolic process taf14 8.89e-06 10 912 8 GO:0006094 BP gluconeogenesis taf14 6.85e-05 131 912 37 GO:0044283 BP small molecule biosynthetic process taf14 3.5e-05 23 912 12 GO:0046165 BP alcohol biosynthetic process taf14 8.06e-07 89 912 32 GO:0030312 CC external encapsulating structure taf14 8.06e-07 89 912 32 GO:0005618 CC cell wall taf14 8.06e-07 89 912 32 GO:0009277 CC fungal-type cell wall taf14 1.44e-06 47 912 24 KEGG:00010 ke Glycolysis / Gluconeogenesis taf14 0.000798 142 912 44 KEGG:03010 ke Ribosome thi2 1.79e-05 31 712 13 GO:0009066 BP aspartate family amino acid metabolic process thi2 3.01e-05 180 712 40 GO:0042180 BP cellular ketone metabolic process thi2 1.72e-05 176 712 40 GO:0006082 BP organic acid metabolic process thi2 1.72e-05 176 712 40 GO:0043436 BP oxoacid metabolic process thi2 1.72e-05 176 712 40 GO:0019752 BP carboxylic acid metabolic process thi2 1.05e-05 12 712 8 GO:0019319 BP hexose biosynthetic process thi2 5.39e-08 18 712 12 GO:0006090 BP pyruvate metabolic process thi2 6.06e-05 58 712 18 GO:0006006 BP glucose metabolic process thi2 1.18e-06 10 712 8 GO:0006094 BP gluconeogenesis thi2 3.89e-06 11 712 8 GO:0000786 CC nucleosome thi2 3.89e-06 11 712 8 GO:0000788 CC nuclear nucleosome thi2 1.45e-09 89 712 32 GO:0030312 CC external encapsulating structure thi2 1.45e-09 89 712 32 GO:0005618 CC cell wall thi2 1.45e-09 89 712 32 GO:0009277 CC fungal-type cell wall thi2 1.62e-31 142 712 82 KEGG:03010 ke Ribosome thi2 0.000366 47 712 18 KEGG:00010 ke Glycolysis / Gluconeogenesis thi2 8.34e-22 200 712 89 REAC:504343 re Metabolism of proteins thi2 1.15e-18 259 712 99 REAC:504459 re Gene Expression thi2 3.45e-23 164 712 81 REAC:504507 re Translation thi2 3.92e-28 139 712 79 REAC:504506 re Eukaryotic Translation Elongation thi2 3.92e-28 139 712 79 REAC:504505 re Peptide chain elongation thi2 9.32e-29 137 712 79 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site thi2 9.32e-29 137 712 79 REAC:502806 re Hydrolysis of eEF1A:GTP thi2 2.14e-28 135 712 78 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA thi2 3.92e-28 139 712 79 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction thi2 1.5e-23 159 712 80 REAC:504612 re Eukaryotic Translation Initiation thi2 1.5e-23 159 712 80 REAC:504611 re Cap-dependent Translation Initiation thi2 2.32e-09 74 712 36 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S thi2 2.32e-09 74 712 36 REAC:504671 re Translation initiation complex formation thi2 1.42e-09 73 712 36 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize thi2 2.32e-09 74 712 36 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation thi2 2.32e-09 74 712 36 REAC:504769 re Ribosomal scanning and start codon recognition thi2 1.42e-09 73 712 36 REAC:503952 re Ribosomal scanning thi2 2.32e-09 74 712 36 REAC:504040 re Start codon recognition thi2 3.15e-10 67 712 35 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex thi2 3.15e-10 67 712 35 REAC:502531 re Formation of the 43S pre-initiation complex thi2 4.42e-28 136 712 78 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit thi2 4.42e-28 136 712 78 REAC:504077 re The 60S subunit joins the translation initiation complex thi2 4.42e-28 136 712 78 REAC:502286 re eIF5B:GTP is hydrolyzed and released thi2 4.48e-29 136 712 79 REAC:504765 re Formation of a pool of free 40S subunits thi2 4.48e-29 136 712 79 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome thi2 0.00109 22 712 11 REAC:504355 re Gluconeogenesis thi2 0.000268 5 712 5 REAC:503441 re Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate thi2 2.4e-25 152 712 80 REAC:504522 re 3' -UTR-mediated translational regulation thi2 2.4e-25 152 712 80 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression thi2 3.45e-14 79 712 44 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit thi2 1.27e-09 76 712 37 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA thi2 4.8e-05 17 712 11 REAC:504394 re Glycolysis thi2 0.000268 5 712 5 REAC:499691 re 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O tis11 7.89e-05 6 323 4 GO:0009081 BP branched chain family amino acid metabolic process tis11 2.39e-12 89 323 24 GO:0030312 CC external encapsulating structure tis11 2.39e-12 89 323 24 GO:0005618 CC cell wall tis11 2.39e-12 89 323 24 GO:0009277 CC fungal-type cell wall tis11 0.000607 10 323 5 KEGG:00280 ke Valine, leucine and isoleucine degradation tis11 6.26e-12 142 323 37 KEGG:03010 ke Ribosome tis11 7.3e-10 200 323 38 REAC:504343 re Metabolism of proteins tis11 1.72e-07 259 323 40 REAC:504459 re Gene Expression tis11 9.89e-10 164 323 34 REAC:504507 re Translation tis11 3.56e-11 139 323 33 REAC:504506 re Eukaryotic Translation Elongation tis11 3.56e-11 139 323 33 REAC:504505 re Peptide chain elongation tis11 2.27e-11 137 323 33 REAC:502806 re Hydrolysis of eEF1A:GTP tis11 2.27e-11 137 323 33 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site tis11 1.43e-11 135 323 33 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA tis11 3.56e-11 139 323 33 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction tis11 3.84e-10 159 323 34 REAC:504612 re Eukaryotic Translation Initiation tis11 3.84e-10 159 323 34 REAC:504611 re Cap-dependent Translation Initiation tis11 1.8e-11 136 323 33 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit tis11 1.8e-11 136 323 33 REAC:504077 re The 60S subunit joins the translation initiation complex tis11 1.8e-11 136 323 33 REAC:502286 re eIF5B:GTP is hydrolyzed and released tis11 2.65e-12 136 323 34 REAC:504765 re Formation of a pool of free 40S subunits tis11 2.65e-12 136 323 34 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome tis11 9.46e-11 152 323 34 REAC:504522 re 3' -UTR-mediated translational regulation tis11 9.46e-11 152 323 34 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression tis11 1.08e-08 79 323 22 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit tye7 8.16e-06 23 1142 14 GO:0046165 BP alcohol biosynthetic process tye7 9.88e-07 18 1142 13 GO:0006090 BP pyruvate metabolic process tye7 1.25e-05 402 1142 108 GO:0044429 CC mitochondrial part tye7 7.64e-09 89 1142 40 GO:0030312 CC external encapsulating structure tye7 7.64e-09 89 1142 40 GO:0005618 CC cell wall tye7 7.64e-09 89 1142 40 GO:0009277 CC fungal-type cell wall tye7 9.78e-06 11 1142 9 GO:0000786 CC nucleosome tye7 9.78e-06 11 1142 9 GO:0000788 CC nuclear nucleosome tye7 1.31e-07 47 1142 28 KEGG:00010 ke Glycolysis / Gluconeogenesis tye7 3e-21 142 1142 84 KEGG:03010 ke Ribosome tye7 1.33e-05 73 1142 36 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize tye7 1.33e-05 73 1142 36 REAC:503952 re Ribosomal scanning tye7 1.71e-15 152 1142 82 REAC:504522 re 3' -UTR-mediated translational regulation tye7 1.71e-15 152 1142 82 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression tye7 4.89e-10 79 1142 46 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit tye7 1.45e-05 76 1142 37 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA tye7 7.71e-13 200 1142 94 REAC:504343 re Metabolism of proteins tye7 7.45e-09 259 1142 104 REAC:504459 re Gene Expression tye7 4.5e-14 164 1142 84 REAC:504507 re Translation tye7 3.86e-18 139 1142 81 REAC:504506 re Eukaryotic Translation Elongation tye7 3.86e-18 139 1142 81 REAC:504505 re Peptide chain elongation tye7 5.77e-18 137 1142 80 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site tye7 5.77e-18 137 1142 80 REAC:502806 re Hydrolysis of eEF1A:GTP tye7 8.59e-18 135 1142 79 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA tye7 3.86e-18 139 1142 81 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction tye7 6.37e-14 159 1142 82 REAC:504612 re Eukaryotic Translation Initiation tye7 6.37e-14 159 1142 82 REAC:504611 re Cap-dependent Translation Initiation tye7 9.08e-07 67 1142 36 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex tye7 9.08e-07 67 1142 36 REAC:502531 re Formation of the 43S pre-initiation complex tye7 1.63e-17 136 1142 79 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit tye7 1.63e-17 136 1142 79 REAC:504077 re The 60S subunit joins the translation initiation complex tye7 1.63e-17 136 1142 79 REAC:502286 re eIF5B:GTP is hydrolyzed and released tye7 3.01e-18 136 1142 80 REAC:504765 re Formation of a pool of free 40S subunits tye7 3.01e-18 136 1142 80 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome yap3 2.31e-05 90 298 15 GO:0019236 BP response to pheromone yap3 7.47e-05 67 298 12 GO:0000749 BP response to pheromone during conjugation with cellular fusion yap3 2.4e-05 34 298 9 GO:0043900 BP regulation of multi-organism process yap3 2.4e-05 34 298 9 GO:0046999 BP regulation of conjugation yap3 2.4e-05 34 298 9 GO:0031137 BP regulation of conjugation with cellular fusion yap3 5.08e-09 89 298 20 GO:0030312 CC external encapsulating structure yap3 5.08e-09 89 298 20 GO:0005618 CC cell wall yap3 5.08e-09 89 298 20 GO:0009277 CC fungal-type cell wall yap3 0.000175 3 298 3 REAC:499530 re 1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+ yap3 0.000554 8 298 4 REAC:504416 re Synaptic Transmission yap3 0.000554 8 298 4 REAC:504415 re Transmission across Chemical Synapses yap3 0.000175 3 298 3 REAC:504608 re Glyceraldehyde 3-phosphate, NAD+, and orthophosphate react to form 1,3-bisphosphoglycerate, NADH, and H+ yap3 0.000175 3 298 3 REAC:501949 re D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ yap7 2.37e-05 18 499 8 GO:0006090 BP pyruvate metabolic process yap7 3.07e-05 10 499 6 GO:0006094 BP gluconeogenesis yap7 1.63e-10 89 499 27 GO:0030312 CC external encapsulating structure yap7 1.63e-10 89 499 27 GO:0005618 CC cell wall yap7 1.63e-10 89 499 27 GO:0009277 CC fungal-type cell wall yap7 3.61e-06 11 499 7 GO:0005199 MF structural constituent of cell wall yap7 2.17e-05 268 499 40 GO:0005215 MF transporter activity yap7 1.31e-05 244 499 38 GO:0022892 MF substrate-specific transporter activity yap7 0.00134 47 499 14 KEGG:00010 ke Glycolysis / Gluconeogenesis yap7 2.74e-28 142 499 68 KEGG:03010 ke Ribosome yap7 2.63e-21 152 499 64 REAC:504522 re 3' -UTR-mediated translational regulation yap7 2.63e-21 152 499 64 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression yap7 2.76e-13 79 499 37 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit yap7 1.32e-06 76 499 27 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA yap7 4.32e-15 200 499 66 REAC:504343 re Metabolism of proteins yap7 9.61e-13 259 499 73 REAC:504459 re Gene Expression yap7 6.59e-20 164 499 65 REAC:504507 re Translation yap7 4.04e-23 139 499 63 REAC:504506 re Eukaryotic Translation Elongation yap7 4.04e-23 139 499 63 REAC:504505 re Peptide chain elongation yap7 1.43e-23 137 499 63 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site yap7 1.43e-23 137 499 63 REAC:502806 re Hydrolysis of eEF1A:GTP yap7 4.53e-23 135 499 62 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA yap7 4.04e-23 139 499 63 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction yap7 5.72e-20 159 499 64 REAC:504612 re Eukaryotic Translation Initiation yap7 5.72e-20 159 499 64 REAC:504611 re Cap-dependent Translation Initiation yap7 7.02e-07 74 499 27 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S yap7 7.02e-07 74 499 27 REAC:504671 re Translation initiation complex formation yap7 5.06e-07 73 499 27 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize yap7 7.02e-07 74 499 27 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation yap7 7.02e-07 74 499 27 REAC:504769 re Ribosomal scanning and start codon recognition yap7 5.06e-07 73 499 27 REAC:503952 re Ribosomal scanning yap7 7.02e-07 74 499 27 REAC:504040 re Start codon recognition yap7 5.94e-08 67 499 27 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex yap7 5.94e-08 67 499 27 REAC:502531 re Formation of the 43S pre-initiation complex yap7 7.62e-23 136 499 62 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit yap7 7.62e-23 136 499 62 REAC:504077 re The 60S subunit joins the translation initiation complex yap7 7.62e-23 136 499 62 REAC:502286 re eIF5B:GTP is hydrolyzed and released yap7 8.42e-24 136 499 63 REAC:504765 re Formation of a pool of free 40S subunits yap7 8.42e-24 136 499 63 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome yap7 6.24e-05 5 499 5 REAC:503441 re Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate yap7 2.51e-05 17 499 10 REAC:504394 re Glycolysis yap7 6.24e-05 5 499 5 REAC:499691 re 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O zds1 1.6e-06 180 391 29 GO:0042180 BP cellular ketone metabolic process zds1 3.16e-06 176 391 28 GO:0006082 BP organic acid metabolic process zds1 3.16e-06 176 391 28 GO:0043436 BP oxoacid metabolic process zds1 3.16e-06 176 391 28 GO:0019752 BP carboxylic acid metabolic process zds1 4.44e-05 8 391 5 GO:0022610 BP biological adhesion zds1 4.44e-05 8 391 5 GO:0007155 BP cell adhesion zds1 7.14e-05 5 391 4 GO:0016337 BP cell-cell adhesion zds1 4.88e-06 23 391 9 GO:0046165 BP alcohol biosynthetic process zds1 1.46e-05 15 391 7 GO:0046364 BP monosaccharide biosynthetic process zds1 2.11e-06 12 391 7 GO:0019319 BP hexose biosynthetic process zds1 3.84e-07 18 391 9 GO:0006090 BP pyruvate metabolic process zds1 3.57e-07 10 391 7 GO:0006094 BP gluconeogenesis zds1 3.45e-07 89 391 20 GO:0030312 CC external encapsulating structure zds1 3.45e-07 89 391 20 GO:0005618 CC cell wall zds1 3.45e-07 89 391 20 GO:0009277 CC fungal-type cell wall zds1 9.61e-06 47 391 16 KEGG:00010 ke Glycolysis / Gluconeogenesis zds1 5.08e-18 142 391 51 KEGG:03010 ke Ribosome zds1 2.42e-07 17 391 11 REAC:504394 re Glycolysis zds1 2.06e-05 5 391 5 REAC:499691 re 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O zds1 8.25e-06 22 391 11 REAC:504355 re Gluconeogenesis zds1 2.06e-05 5 391 5 REAC:503441 re Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate zds1 5.42e-10 200 391 50 REAC:504343 re Metabolism of proteins zds1 1.38e-07 259 391 54 REAC:504459 re Gene Expression zds1 1.09e-11 164 391 47 REAC:504507 re Translation zds1 4.26e-14 139 391 46 REAC:504506 re Eukaryotic Translation Elongation zds1 4.26e-14 139 391 46 REAC:504505 re Peptide chain elongation zds1 2.21e-14 137 391 46 REAC:502806 re Hydrolysis of eEF1A:GTP zds1 2.21e-14 137 391 46 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site zds1 1.13e-14 135 391 46 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA zds1 4.26e-14 139 391 46 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction zds1 2.89e-12 159 391 47 REAC:504612 re Eukaryotic Translation Initiation zds1 2.89e-12 159 391 47 REAC:504611 re Cap-dependent Translation Initiation zds1 0.000306 67 391 18 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex zds1 0.000306 67 391 18 REAC:502531 re Formation of the 43S pre-initiation complex zds1 1.59e-14 136 391 46 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit zds1 1.59e-14 136 391 46 REAC:504077 re The 60S subunit joins the translation initiation complex zds1 1.59e-14 136 391 46 REAC:502286 re eIF5B:GTP is hydrolyzed and released zds1 2.44e-15 136 391 47 REAC:504765 re Formation of a pool of free 40S subunits zds1 2.44e-15 136 391 47 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome zds1 4.01e-13 152 391 47 REAC:504522 re 3' -UTR-mediated translational regulation zds1 4.01e-13 152 391 47 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression zds1 7.3e-10 79 391 29 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit abf1 4.97e-06 456 858 95 GO:0044281 BP small molecule metabolic process abf1 0.000838 47 858 16 KEGG:00010 ke Glycolysis / Gluconeogenesis abf1 0.00249 616 858 113 KEGG:01100 ke Metabolic pathways abf1 0.00127 13 858 7 KEGG:00740 ke Riboflavin metabolism abf1 0.000969 23 858 10 KEGG:00260 ke Glycine, serine and threonine metabolism gcr1 9.41e-08 18 1431 15 GO:0006090 BP pyruvate metabolic process gcr1 1.14e-12 456 1431 168 GO:0044281 BP small molecule metabolic process gcr1 6.76e-07 131 1431 55 GO:0044283 BP small molecule biosynthetic process gcr1 2.25e-08 180 1431 74 GO:0042180 BP cellular ketone metabolic process gcr1 2.34e-06 113 1431 48 GO:0055086 BP cellular nucleobase, nucleoside and nucleotide metabolic process gcr1 1.99e-07 79 1431 39 GO:0006753 BP nucleoside phosphate metabolic process gcr1 1.99e-07 79 1431 39 GO:0009117 BP nucleotide metabolic process gcr1 1.6e-07 29 1431 20 GO:0009259 BP ribonucleotide metabolic process gcr1 1.6e-07 29 1431 20 GO:0006163 BP purine nucleotide metabolic process gcr1 7.55e-08 26 1431 19 GO:0009150 BP purine ribonucleotide metabolic process gcr1 5.96e-06 39 1431 22 GO:0009165 BP nucleotide biosynthetic process gcr1 4.38e-06 26 1431 17 GO:0009260 BP ribonucleotide biosynthetic process gcr1 1.92e-06 25 1431 17 GO:0006164 BP purine nucleotide biosynthetic process gcr1 2.46e-06 23 1431 16 GO:0009152 BP purine ribonucleotide biosynthetic process gcr1 1.8e-08 176 1431 73 GO:0006082 BP organic acid metabolic process gcr1 1.8e-08 176 1431 73 GO:0043436 BP oxoacid metabolic process gcr1 1.8e-08 176 1431 73 GO:0019752 BP carboxylic acid metabolic process gcr1 1.3e-05 193 1431 70 GO:0034641 BP cellular nitrogen compound metabolic process gcr1 5e-06 44 1431 24 GO:0032268 BP regulation of cellular protein metabolic process gcr1 8.54e-06 37 1431 21 GO:0006417 BP regulation of translation gcr1 3.09e-08 89 1431 44 GO:0030312 CC external encapsulating structure gcr1 3.09e-08 89 1431 44 GO:0005618 CC cell wall gcr1 3.09e-08 89 1431 44 GO:0009277 CC fungal-type cell wall gcr1 2.02e-07 394 1431 133 GO:0044425 CC membrane part gcr1 3.49e-06 33 1431 20 GO:0016469 CC proton-transporting two-sector ATPase complex gcr1 3.69e-06 19 1431 14 GO:0045259 CC proton-transporting ATP synthase complex gcr1 1.35e-09 99 1431 50 GO:0044455 CC mitochondrial membrane part gcr1 3.69e-06 19 1431 14 GO:0005753 CC mitochondrial proton-transporting ATP synthase complex gcr1 3.39e-06 11 1431 10 GO:0000786 CC nucleosome gcr1 3.39e-06 11 1431 10 GO:0000788 CC nuclear nucleosome gcr1 1.89e-41 142 1431 122 KEGG:03010 ke Ribosome gcr1 8.24e-32 152 1431 126 REAC:504522 re 3' -UTR-mediated translational regulation gcr1 8.24e-32 152 1431 126 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression gcr1 2.81e-25 79 1431 74 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit gcr1 2.48e-08 76 1431 54 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA gcr1 7.07e-27 200 1431 147 REAC:504343 re Metabolism of proteins gcr1 2.45e-16 259 1431 160 REAC:504459 re Gene Expression gcr1 6.1e-30 164 1431 131 REAC:504507 re Translation gcr1 1.24e-32 139 1431 119 REAC:504506 re Eukaryotic Translation Elongation gcr1 1.24e-32 139 1431 119 REAC:504505 re Peptide chain elongation gcr1 7.03e-33 137 1431 118 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site gcr1 7.03e-33 137 1431 118 REAC:502806 re Hydrolysis of eEF1A:GTP gcr1 3.86e-33 135 1431 117 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA gcr1 1.24e-32 139 1431 119 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction gcr1 9.44e-31 159 1431 129 REAC:504612 re Eukaryotic Translation Initiation gcr1 9.44e-31 159 1431 129 REAC:504611 re Cap-dependent Translation Initiation gcr1 8.72e-08 74 1431 52 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S gcr1 8.72e-08 74 1431 52 REAC:504671 re Translation initiation complex formation gcr1 1.62e-07 73 1431 51 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize gcr1 8.72e-08 74 1431 52 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation gcr1 3.27e-07 74 1431 51 REAC:504769 re Ribosomal scanning and start codon recognition gcr1 1.62e-07 73 1431 51 REAC:503952 re Ribosomal scanning gcr1 3.27e-07 74 1431 51 REAC:504040 re Start codon recognition gcr1 1.12e-07 67 1431 48 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex gcr1 1.12e-07 67 1431 48 REAC:502531 re Formation of the 43S pre-initiation complex gcr1 1.88e-32 136 1431 117 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit gcr1 1.88e-32 136 1431 117 REAC:504077 re The 60S subunit joins the translation initiation complex gcr1 1.88e-32 136 1431 117 REAC:502286 re eIF5B:GTP is hydrolyzed and released gcr1 1.88e-32 136 1431 117 REAC:504765 re Formation of a pool of free 40S subunits gcr1 1.88e-32 136 1431 117 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome hsf1 7.07e-08 456 1067 120 GO:0044281 BP small molecule metabolic process hsf1 9.3e-08 131 1067 47 GO:0044283 BP small molecule biosynthetic process hsf1 3.12e-06 180 1067 55 GO:0042180 BP cellular ketone metabolic process hsf1 7.62e-06 176 1067 53 GO:0006082 BP organic acid metabolic process hsf1 7.62e-06 176 1067 53 GO:0043436 BP oxoacid metabolic process hsf1 7.62e-06 176 1067 53 GO:0019752 BP carboxylic acid metabolic process hsf1 1.15e-05 70 1067 27 GO:0070925 BP organelle assembly hsf1 7.33e-06 328 1067 86 GO:0022613 BP ribonucleoprotein complex biogenesis hsf1 2.53e-06 306 1067 83 GO:0042254 BP ribosome biogenesis hsf1 6.86e-06 61 1067 25 GO:0042273 BP ribosomal large subunit biogenesis hsf1 1.3e-05 82 1067 30 GO:0022618 BP ribonucleoprotein complex assembly hsf1 3.1e-07 60 1067 27 GO:0042255 BP ribosome assembly hsf1 3.82e-09 51 1067 27 GO:0042257 BP ribosomal subunit assembly hsf1 2.56e-06 38 1067 19 GO:0000027 BP ribosomal large subunit assembly hsf1 4.38e-06 11 1067 9 GO:0006450 BP regulation of translational fidelity hsf1 3.44e-06 89 1067 33 GO:0030312 CC external encapsulating structure hsf1 3.44e-06 89 1067 33 GO:0005618 CC cell wall hsf1 3.44e-06 89 1067 33 GO:0009277 CC fungal-type cell wall hsf1 4.38e-06 11 1067 9 GO:0000786 CC nucleosome hsf1 4.38e-06 11 1067 9 GO:0000788 CC nuclear nucleosome hsf1 2e-53 142 1067 117 KEGG:03010 ke Ribosome hsf1 1.54e-34 200 1067 129 REAC:504343 re Metabolism of proteins hsf1 8.55e-26 259 1067 140 REAC:504459 re Gene Expression hsf1 6.96e-44 164 1067 123 REAC:504507 re Translation hsf1 5.27e-50 139 1067 116 REAC:504506 re Eukaryotic Translation Elongation hsf1 5.27e-50 139 1067 116 REAC:504505 re Peptide chain elongation hsf1 4.91e-50 137 1067 115 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site hsf1 4.91e-50 137 1067 115 REAC:502806 re Hydrolysis of eEF1A:GTP hsf1 4.46e-50 135 1067 114 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA hsf1 5.27e-50 139 1067 116 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction hsf1 3.37e-44 159 1067 121 REAC:504612 re Eukaryotic Translation Initiation hsf1 3.37e-44 159 1067 121 REAC:504611 re Cap-dependent Translation Initiation hsf1 7.51e-14 74 1067 51 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S hsf1 7.51e-14 74 1067 51 REAC:504671 re Translation initiation complex formation hsf1 2.07e-13 73 1067 50 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize hsf1 7.51e-14 74 1067 51 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation hsf1 4.81e-13 74 1067 50 REAC:504769 re Ribosomal scanning and start codon recognition hsf1 2.07e-13 73 1067 50 REAC:503952 re Ribosomal scanning hsf1 4.81e-13 74 1067 50 REAC:504040 re Start codon recognition hsf1 4.3e-14 67 1067 48 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex hsf1 4.3e-14 67 1067 48 REAC:502531 re Formation of the 43S pre-initiation complex hsf1 2.26e-49 136 1067 114 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit hsf1 2.26e-49 136 1067 114 REAC:504077 re The 60S subunit joins the translation initiation complex hsf1 2.26e-49 136 1067 114 REAC:502286 re eIF5B:GTP is hydrolyzed and released hsf1 2.26e-49 136 1067 114 REAC:504765 re Formation of a pool of free 40S subunits hsf1 2.26e-49 136 1067 114 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome hsf1 3.7e-48 152 1067 121 REAC:504522 re 3' -UTR-mediated translational regulation hsf1 3.7e-48 152 1067 121 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression hsf1 4.36e-33 79 1067 71 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit hsf1 9.62e-15 76 1067 53 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA mcm1 1.17e-05 18 1382 13 GO:0006007 BP glucose catabolic process rap1 1.05e-12 456 1273 152 GO:0044281 BP small molecule metabolic process rap1 3.06e-07 131 1273 51 GO:0044283 BP small molecule biosynthetic process rap1 8.39e-08 180 1273 66 GO:0042180 BP cellular ketone metabolic process rap1 2.69e-09 113 1273 50 GO:0055086 BP cellular nucleobase, nucleoside and nucleotide metabolic process rap1 5.28e-08 79 1273 37 GO:0006753 BP nucleoside phosphate metabolic process rap1 5.28e-08 79 1273 37 GO:0009117 BP nucleotide metabolic process rap1 1.89e-07 176 1273 64 GO:0006082 BP organic acid metabolic process rap1 1.89e-07 176 1273 64 GO:0043436 BP oxoacid metabolic process rap1 1.89e-07 176 1273 64 GO:0019752 BP carboxylic acid metabolic process rap1 2.8e-06 23 1273 15 GO:0046165 BP alcohol biosynthetic process rap1 1.05e-06 58 1273 28 GO:0006006 BP glucose metabolic process rap1 3.49e-06 193 1273 65 GO:0034641 BP cellular nitrogen compound metabolic process rap1 8.4e-07 70 1273 32 GO:0070925 BP organelle assembly rap1 4.74e-07 328 1273 102 GO:0022613 BP ribonucleoprotein complex biogenesis rap1 3.43e-07 306 1273 97 GO:0042254 BP ribosome biogenesis rap1 5.95e-07 82 1273 36 GO:0022618 BP ribonucleoprotein complex assembly rap1 3.71e-08 60 1273 31 GO:0042255 BP ribosome assembly rap1 5.76e-09 51 1273 29 GO:0042257 BP ribosomal subunit assembly rap1 1.53e-05 13 1273 10 GO:0000028 BP ribosomal small subunit assembly rap1 2.01e-07 18 1273 14 GO:0006090 BP pyruvate metabolic process rap1 6.87e-07 89 1273 38 GO:0030312 CC external encapsulating structure rap1 6.87e-07 89 1273 38 GO:0005618 CC cell wall rap1 6.87e-07 89 1273 38 GO:0009277 CC fungal-type cell wall rap1 3.02e-06 47 1273 29 KEGG:00010 ke Glycolysis / Gluconeogenesis rap1 1.68e-56 142 1273 127 KEGG:03010 ke Ribosome rap1 6.63e-43 152 1273 128 REAC:504522 re 3' -UTR-mediated translational regulation rap1 6.63e-43 152 1273 128 REAC:504521 re L13a-mediated translational silencing of Ceruloplasmin expression rap1 9.76e-29 79 1273 73 REAC:502167 re Dissociation of L13a from the 60s ribosomal subunit rap1 2.12e-13 76 1273 57 REAC:501247 re Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA rap1 8.54e-29 200 1273 138 REAC:504343 re Metabolism of proteins rap1 2.9e-16 259 1273 145 REAC:504459 re Gene Expression rap1 7.63e-38 164 1273 130 REAC:504507 re Translation rap1 9.84e-45 139 1273 122 REAC:504506 re Eukaryotic Translation Elongation rap1 9.84e-45 139 1273 122 REAC:504505 re Peptide chain elongation rap1 2.48e-46 137 1273 122 REAC:501007 re Aminoacyl-tRNA binds to the ribosome at the A-site rap1 2.48e-46 137 1273 122 REAC:502806 re Hydrolysis of eEF1A:GTP rap1 1.29e-46 135 1273 121 REAC:503391 re Peptide transfer from P-site tRNA to the A-site tRNA rap1 9.84e-45 139 1273 122 REAC:504153 re Translocation of ribosome by 3 bases in the 3' direction rap1 1.23e-39 159 1273 129 REAC:504612 re Eukaryotic Translation Initiation rap1 1.23e-39 159 1273 129 REAC:504611 re Cap-dependent Translation Initiation rap1 1.19e-12 74 1273 55 REAC:504643 re Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S rap1 1.19e-12 74 1273 55 REAC:504671 re Translation initiation complex formation rap1 2.78e-12 73 1273 54 REAC:502542 re Formation of translation initiation complexes containing mRNA that does not circularize rap1 1.19e-12 74 1273 55 REAC:502544 re Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation rap1 7.07e-12 74 1273 54 REAC:504769 re Ribosomal scanning and start codon recognition rap1 2.78e-12 73 1273 54 REAC:503952 re Ribosomal scanning rap1 7.07e-12 74 1273 54 REAC:504040 re Start codon recognition rap1 1.86e-12 67 1273 51 REAC:504610 re Formation of the ternary complex, and subsequently, the 43S complex rap1 1.86e-12 67 1273 51 REAC:502531 re Formation of the 43S pre-initiation complex rap1 8.74e-46 136 1273 121 REAC:504645 re GTP hydrolysis and joining of the 60S ribosomal subunit rap1 8.74e-46 136 1273 121 REAC:504077 re The 60S subunit joins the translation initiation complex rap1 8.74e-46 136 1273 121 REAC:502286 re eIF5B:GTP is hydrolyzed and released rap1 8.74e-46 136 1273 121 REAC:504765 re Formation of a pool of free 40S subunits rap1 8.74e-46 136 1273 121 REAC:503849 re Release of 40S and 60S subunits from the 80S ribosome reb1 5.02e-06 456 530 63 GO:0044281 BP small molecule metabolic process reb1 2.58e-05 180 530 31 GO:0042180 BP cellular ketone metabolic process reb1 1.63e-05 176 530 31 GO:0006082 BP organic acid metabolic process reb1 1.63e-05 176 530 31 GO:0043436 BP oxoacid metabolic process reb1 1.63e-05 176 530 31 GO:0019752 BP carboxylic acid metabolic process reb1 3.65e-06 125 530 26 GO:0006519 BP cellular amino acid and derivative metabolic process reb1 1.64e-05 193 530 33 GO:0034641 BP cellular nitrogen compound metabolic process reb1 5.94e-06 113 530 24 GO:0044106 BP cellular amine metabolic process reb1 3.86e-07 98 530 24 GO:0006520 BP cellular amino acid metabolic process reb1 0.00148 29 530 9 KEGG:00270 ke Cysteine and methionine metabolism reb1 0.00115 18 530 7 KEGG:00290 ke Valine, leucine and isoleucine biosynthesis reb1 0.000303 15 530 7 KEGG:00340 ke Histidine metabolism reb1 2.85e-05 142 530 30 KEGG:03010 ke Ribosome