Supplemental Data. Katayama et al. (2010). Plant Cell 10.1105/tpc.109.073189 The sequences used to generate the phylogenies of KNOX family. MATRIX [ 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 ] [ . . . . . . . . . . . . . . . . . . ] LG3 -LTELMKAQIASHPRYPSLLSAYIECRKVGA-----HP-HVTSLLEEVGVDPE-LDEFMDAYCRVLVRYKEELTRPF----DEAASFLSSIQAQLSDLDHELKEMLLKKYSGCLSRLRSEFLKKRKKGKLPKDARTVLLEWWNTHYRWPYPTEEDKVRLAAMTGLDPKQINNWFINQRKRHWKPS [173] OSH6 -LTELMKAQIAGHPRYPTLLSAYIECRKVGA-----PP-EVASLLKEIGVDPE-LDEFMEAYCRVLVRYKEELSRPF----DEAASFLSSIQTQLSNLDHELKEMLLKKYSGCLSRLRSEFLKKRKKGKLPKDARSALLEWWNTHYRWPYPTEEDKLRLAARTGLDPKQINNWFINQRKRHWKPS [173] OSH71 -LTELMKAQIAGHPSYPSLLSAYIECRKVGA-----PP-EVTTLLEEIGLDPE-LDEFMETYCRVLERYKEELTRPF----DEAASFLTGIHTQLASLDHELKEMLLKKYSGCLSRLRSEFLKKRKKGKLPKDARSALMDWWNTHYRWPYPTEEDKVRLAAMTGLDPKQINNWFINQRKRHWKPS [173] NTH1 -MSDLIKAQIANHPLYPNLLSAYLQCRKVGA-----PQ-EMASILEEIGTDPE-LDDFMESYCAVLLKYKEELSKPF----DEATTFLNNIESQLSSLDNELKETLMRKYSGYLSSLRKEFLKKRKKGKLPKDARTALLEWWNTHYRWPYPTEEEKNRLSEITGLDPKQINNWFINQRKRHWRPS [173] TKn4 -MSDLIKAQIANHPLYPNLLSAYLQCRKVGA-----PQ-EMTSILDEIGADPE-LDEFMESYCAVLVKYKEEFSKPF----DEATSFLSNIESQLSSLDNELKEMLMRKYSGYLSSLRKEFLKKRKKGKLPKEARIVLLDWWKNHYRWPYPTEEEKNRLSEMTGLDQKQINNWFINQRKRHWRPS [173] PKn3 -MSDVVKAQIASHPLYPNLVSAYIQCRKVAA-----PP-EMAALLEELGADPE-LDEFMESYCEVLYKYKEELSKPF----DEAKTFLSSIESQLSNLDQQIKEMLMRKYSGYLSSLRKEFLKKRKKGKLPKDARVALLDWWNSHYRWPYTTEEEKNKLSEATGLDQKQINNWFINQRKRHWRPS [173] KNAT2 -SLSVIKSKIASHPLYPRLLQTYIDCQKVGA-----PM-EIACILEEIGADPE-LDEFMETYCDILVKYKTDLARPF----DEATTFINKIEMQLQNLDRDLKDQLLRKFGSHISSLKLEFSKKKKKGKLPREARQALLDWWNVHNKWPYPTEGDKISLAEETGLDQKQINNWFINQRKRHWKPS [173] KNAT6 -SLTVIKAKIACHPSYPRLLQAYIDCQKVGA-----PP-EIACLLEEIGADPE-LDEFMETYCDILVKYKSDLARPF----DEATCFLNKIEMQLRNLDRDLKDRLLRKFGSRISTLKLEFSKKKKKGKLPREARQALLDWWNLHYKWPYPTEGDKIALADATGLDQKQINNWFINQRKRHWKPS [173] POTH1 -GSNVIKAKIVSHPYYPKLLNAYIDCQKVGA-----PA-GIVNLLEEIGADPE-LDEFMETYCDILLKYKSDLSRPF----DEATTFLNKIEMQLGNLDNELKDRLLRKFGSHLSSLKLEFSKKKKKGKLPKEARQMLLAWWDDHFRWPYPTEADKNSLAESTGLDPKQINNWFINQRKRHWKPS [173] TKn3 -GSNIIKAKILSHPYYPKLLNAYIDCQKVGA-----PA-SIVNLLEEIGADPE-LDEFMETYCDILLKYKSDLSRPF----DEATTFLNNIEMQLGNLDNELKDRLLRKFGSHLSSLKLEFSKKKKKGKLPKEAREMLLAWWYDHFRWPYSTEADKNSLAESTGLDPKQINNWFINQRKRHWKPS [173] NTH22 -ASNIIKAKVVSHPFYPKFVRAYIDCQKVGA-----PP-EIATVLEEIGADPE-LDEFMETYCDILVKYKSDLSRPF----DEATTFLSKIELQLSNLDNELKDRLLRKFGSHLSTLKLEFSKKKKKGKLPKEARQMLLAWWNDHYRWPYPTEADKNSLAESTGLDPKQINNWFINQRKRHWKPS [173] Pkn1 -GIGLIKAKIASHPSYPKLLEAYIDCQKVGA-----PP-EIASFLDEIGDDPE-LDIFMETYCDILVKYKSDLSRPF----DEAKTFLNKIETQLSNLDRELKSRLLQKYGGHISSLKLEFSKKKKKGKLPKDARQILLEWWKGHYRWPYPTEDDKISLAELTGLDQKQINNWFINQRKRHWKPS [173] PKn2 -SSVMIKAKIASHPCYPKLLHAYIDCQKVGA-----PP-EIATVLDEIGADPE-LDEFMETYYDMLVKYKSDLSKPF----HEATTFLNTIETQLSNLERQLKNTLLRKYGSHLSSLKLEFSKKKKKGKLPKEARQTLLDWWSDHYKWPYPTEADKIALAESTGLDQKQINNWFINQRKRHWKPS [173] DOH -AEEEMKARIASHPRYPHLLEAYIDCQKVGA-----PP-DIASLLEEIGSDPE-LDEFMEMYCDVLVKYRRDLERPF----DEATAFLNTMEVQLSDLERDLKEKLLRKYSGYLSSLKQEFSKKKKKGKLPKEARQILFEWWTAHYKWPYPTEADKIALAEATGLDQKQINNWFINQRKRHWKPA [173] NTH9 -PETDIRAKISSHPLYPKLLRTYIDCHKVGA-----PSDEIVDMLDNISDDSE-LDAFMETYCDVLAKFKSDLERPF----NEATTFLNDIETQLTNLENEIKDKLMRKYSGYISSLKQEFSKKNKKGKLPREARQILLNWWTTHYKWPYPTEGEKICLAESTGLDPKQINNWFINQRKRHWKPS [174] CRKNOX1 -RSDVIRSKIMSHPTYPRLVMAYVNCHKIGA-----PP-EVATSLEEIGADPE-LDNFMETYCNVLQKYHDELMQPY----KEAMTFFRKIELQLNALDQKVKEQLLRKYSGYIYKLKQEFLKKKKKGKLPKNAREKLLDWWNQHYKWPYPSEAEKAALAETTGLDQKQINNWFINQRKRHWKPS [173] CRKNOX2 -RDDLIRTKIVSHPSYPRLVMAYVNCYKIGA-----PE-DAALILEEVGADPE-LDNFMELYCNVLQRYHEELTHPY----KEAMAFFKKIELQLDAIDQKLKEQLLRKYSGYIFKLKQEFLKKKKKGKLPREARQMLLDWWTQHYKWPYPSEAEKTALAESTGLDQKQINNWFINQRKRHWKPS [173] RaSTM -DNNILKAKIMSHPHYPKLLSAYINCQKVGA-----PP-EVVARLEEAGGDPA-LDQFMEAYCEMLTKYEQELSKPF----KEAMMFLSRIDAQFKSLDRELKGQLLRKYSGYLSSLKQEFLKKRKKGKLPKEARQQLLDWWTRHYKWPYPSESQKMALAESTGLDQKQINNWFINQRKRHWKPS [173] STM -SSASVKAKIMAHPHYHRLLAAYVNCQKVGA-----PP-EVVARLEEAGEDPG-LDQFMEAYCEMLVKYEQELSKPF----KEAMVFLQRVECQFKSLDRELKGQLLRKYSGYLGSLKQEFMKKRKKGKLPKEARQQLLDWWSRHYKWPYPSEQQKLALAESTGLDQKQINNWFINQRKRHWKPS [173] BoSTM -SSLLVKAKIMAHPHYHRLLLAYVNCQKVGA-----PP-EVQARLEETGEDPG-LDQFMEAYCEMLVKYEQELSKPF----KEAMVFLQHVECQFKSLDRELKGQLLRKYSGYLGSLKQEFMKKRKKGKLPKEARQQLLDWWSRHYKWPYPSEQQKLALAESTGLDQKQINNWFINQRKRHWKPS [173] SrSTM1 -GGGSVKSKIMAHPHYPRLLAAYVNCQKIGA-----PP-EVVAKLEEAGEDPA-LDQFMEAYCEMLTKYEQELSKPF----KEAMLFLSRIECQFKALDRELKGQLLRRYSGYLGNLKQEFMKKRKKGKLPKEARQQLLDWWSRHYKWPYPSESQKLALAESTGLDQKQINNWFINQRKRHWKPS [173] SsSTM1 -GGSSVKSKIIAHPHYPRLLAAYVSCQKIGA-----PP-EVVAKLEEVGEDPA-LDQFMEAYCGMLTKYEQELSKPF----KDAMLFFSRFECQFKALDHELKGQLLRKYSGYLGNLKQEFMKKRKKGKLPKEARQQLLDWWSRHYKWPYPSESQKLALAESTGLEQKQINNWFINQRKRHWKPS [173] ina -DNDSVKAKIMAHPYYHKLLAAYINCQKIGA-----PP-EVAVKLEEAGEDPA-LDQFMEAYCEMLSKYEQELSKPF----REAMLFLSRIECQFKALDRELKGQLLRKYSGYLGSLKQEFMKKRKKGKLPKEARQQLLDWWSRHYKWPYPSESQKLALAEQTGLDQKQINNWFINQRKRHWKPS [173] hirz -DESSLKAKIMAHPHYHRLLAAYVNCHKIGA-----PP-EVVSRLEEAGEDPG-LDQLMEAYSEMLSKYEQELSKPF----KEAMLFLSRIESQFKALDIELKGQLLRKYSGYLGSLKQEFMKKRKKGKLPKEARQQLLEWWSRHYKWPYPSESQKLALAESTGLDQKQINNWFINQRKRHWKPS [173] LET6 -SSSSIKSKIMAHPHYHRLLTAYLNCQKIGA-----PP-EVVARLEEIGEDPA-LDQFMEAYCEMLTKYEQELSKPF----KEAMVFLSRIECQFKALDRELKGQLLRKYSGYLGSLKQEFMKKRKKGKLPKEARQQLVDWWLRHIKWPYPSESQKLALAESTGLDQKQINNWFINQRKRHWKPS [173] TKn2 -SSSSIKSKIMLNPHYHRLLTAYLNCQKIGA-----PP-EVVARLEEIGEDPA-LDQFMEAYCEMLTKYEQELSKPF----KEAMVFLSRIECQFKALDRELKGQLLRKYSGYLGSLKQEFMKKRKKGKLPKEARQQLVDWWLRHIKWPYPSESQKLALAESTGLDQKQINNWFINQRKRHWKPS [173] NTH15 -SSSSIKSKIMAHPHYPRLLSAYVNCQKIGA-----PP-EVVARLEEVGEDPA-LDQFMEAYCEMLTKYEQELSKPF----KEAMVFLSRIECQFKALDQELKGQLLRKYSGYLGSLKQEFMKKRKKGKLPKEARQQLLDWWTRHYKWPYPSESQKLALAESTGLDQKQINNWFINQRKRHWKPS [173] PhSTM -CSSNIKAKIMAHPHYPRLLAAYINCQKIGA-----PP-EVVARLEEVGEDPA-LDQFMEAYCEMLTKYEQELSKPF----KEAMVFLSRIECQFKALDRELKGQLLRKYSGYLGSLKQEFMKKRKKGKLPKEARQQLLDWWTRHYKWPYPSESQKLALAESTGLDQKQINNWFINQRKRHWKPS [173] Hop1 -SSSAVKAKIMAHPHYHRLLEAYINCQKVGA-----PS-EVVTRLEEAGEDPA-LDQFMEAYCEMLIKYEQELSKPL----KEAMLFLQRIEVQFKNLDRELKGQLLRKYSGYLGSLKQEFMKKRKKGKLPKEARQQLLEWWSRHYKWPYPSESQKLALAESTGLDQKQINNWFINQRKRHWKPS [173] MtKNOX1 -SSSSVKSKIMAHPHYHRLLEAYINCQKVGA-----PS-EVVARLEEAGEDPA-LDQFMEAYCEMLIKYEQELSKPL----KEAMLFLQRIEVQFKNLDRELKGQLLRKYSGYLGSLKQEFMKKRKKGKLPKEARQQLLEWWSRHYKWPYPSESQKLALAESTGLDQKQINNWFINQRKRHWKPS [173] SBH1 -SSSAVKAKIMAHPHYHRLLAAYVNCQKVGA-----PP-EVVARLEEAGEDPA-LDQFMEAYCEMLTKYEQELSKPL----KEAMLFLQRIECQFKNLDRDLKGQLLRKYSGYLGSLKQEFMKKRKKGKLPKEARQQLLEWWNRHYKWPYPSESQKLALAESTGLDQKQINNWFINQRKRHWKPS [173] PsSTM -TTCSIKAKIMSHPHYNRLLSAYVNCQKIGA-----PP-EVVARLEEAGQDPA-LDQFMEAYCEMLTKYEQELSKPL----KEAMVFLQRVEYQFKALDQELKGQLLRRYSGYLGSLKQEFMKKRKKGKLPKEARQQLLDWWNRHYKWPYPSESQKLALAESTGLDQKQINNWFINQRKRHWKPS [173] HjSTM -TTCSIKAKIMSHPHYNRLLSAYVNCQKIGA-----PP-EVVARLEEAGQDPA-LDQFMEAYCEMLTKYEQELSKPL----KEAMVFLQRVEYQFKALDQELKGQLLRRYSGYLGSLKQEFMKKRKKGKLPKEARQQLLDWWNRHYKWPYPSESQKLALAESTGLDQKQINNWFINQRKRHWKPS [173] CdSTM -TTCSIKAKIMSHPHYNRLLLAYVNCQKIGA-----PP-EVVARLEEAGQDPA-LDQFMEAYCEMLTKYEQELSKPL----KEAMVFLQRVEYQFKALDQELKGQLLRRYSGYLGSLKQEFMKKRKKGKLPKEARQQLLDWWSRHYKWPYPSESQKLALAESTGLDQKQINNWFINQRKRHWKPS [173] WsSTM -PLCSIKAKIMSHPHYTRLLSAYVNCQKVGA-----PP-EVVARLEEAGQDPA-LDQFMEAYCEMLTKYEQELSKPL----KEAMLFLQRVEFQFKALDRELKGQLLRRYSGYLGSLKQEFMKKRKKGKLPKEARQQLLDWWSRHYKWPYPSESQKLALAESTGLDQKQINNWFINQRKRHWKPS [173] TmSTM -PICSIKAKIMSHPHYTRLLAAYVNCQKVGA-----PP-EVVARLEEAGLDPA-LDQFMEAYCEMLIKYEQELSKPL----KEAMLFLQRVEYQFKSLDHELKGQLLRRYSGYLGSLKQEFMKKRKKGKLPKEARQQLLDWWSRHYKWPYPSESQKLALAESTGLDQKQINNWFINQRKRHWKPS [173] Hvh21 -DVEAIKAKIISHPHHSSLLAAYLDCQKVGA-----PP-EVSARLTAVATEPE-LDQFMEAYHEMLVKYREELTRPL----QEAMEFLRRVETQLNSLDQELKHHLLKKYSGYLSSLKQELSKKKKKGKLPKEARQQLLSWWEMHYKWPYPSESQKVALAESTGLDLKQINNWFINQRKRHWKPT [173] HvKNOX3 -DVEAIKAKIISHPHYSSLLAAYLDCQKVGA-----PP-EVSARLTAVATEPE-LDQFMEAYHEMLVKYREELTRPL----QEAMEFLRRVETQLNSLDQELKHHLLKKYSGYLSSLKQELSKKKKKGKLPKEARQQLLSWWEMHYKWPYPSESQKVALAESTGLDLKQINNWFINQRKRHWKPT [173] Wknox1a -DVEAIKAKIISHPHYSSLLAAYLDCQKVGA-----PP-EVLARLTAVATEPE-LDQFMEAYHEMLVKYREELTRPL----QEAMEFLRRVETQLNSLDQELKHHLLKKYSGYLSSLKQELSKKKKKGKLPKDARQQLLSWWEMHYKWPYPSESQKVALAESTGLDLKQINNWFINQRKRHWKPS [173] OSH1 -DVEAIKAKIISHPHYSSLLAAYLDCQKVGA-----PP-EVAARLTAVATEPE-LDQFMEAYHEMLVKYREELTRPL----QEAMEFLRRVETQLNTLDQELKHHLLKKYSGYLSSLKQELSKKKKKGKLPKDARQQLLNWWELHYKWPYPSESQKVALAESTGLDLKQINNWFINQRKRHWKPS [173] Kn1 -DVEAIKAKIISHPHYYSLLTAYLECNKVGA-----PP-EVSARLTEIATEPE-LDQFMEAYHEMLVKFREELTRPL----QEAMEFMRRVESQLNSLDQELKHHLLKKYSGYLSSLKQELSKKKKKGKLPKEARQQLLSWWDQHYKWPYPSETQKVALAESTGLDLKQINNWFINQRKRHWKPS [173] KNAP1 -EVEAIKAKIIAHPQYSNLVEAYMDCQRVGA-----PS-DVVPRLSVASKDPE-LDQFMEAYYDMLVKYREELTRPI----QEAMDFMRRIETQLNMLDRELKNHLLRKYSGYLSSLKQELSKKKKKGKLPKEARQKLLSWWELHYKWPYPSESEKVALAESTGLDQKQINNWFINQRKRHWKPS [173] KNAP2 -EVEAIKAKIIAHPQYSNLLEAYMDCQRVGA-----PS-DVVARLSVASKDPE-LDQFMEAYYDMLVKYREELTRPI----QEAMDFMRRIETQLNMLDRELKNHLLRKYSGYLSSLKQELSKKKKKGKLPKDARQKLLSWWELHYKWPYPSESEKVALAESTGLDQKQINNWFINQRKRHWKPS [173] NTH20 -EVDALKAKIIAHPQCSNLLDAYMDCQKVGA-----PP-EVVARLSAVSKDPE-LDQFMEAYYDMLVKYREELTRPL----HEAMDFMRKIETQLNMLDRELKNHLLRKYSGYLSSLKQELSKKKKKGKLPKDARQKLLSWWELHYKWPYPSESEKVALAETTGLDQKQINNWFINQRKRHWKPS [173] TKn1 -VIEALKAKIIAHPQCSNLLDAYMDCQKVGA-----PP-EVAARLSAVSKDPE-LDQFMEAYYDMLVKYREELTRPL----QEAMEFMQKIEAQLNMLDRELKNHLLRKYSGYLSSLKQELSKKKKKGKLPKDARQKLITWWELHYKWPYPSESEKVALAESTGLDQKQINNWFINQRKRHWKPS [173] KNAT1 -DVEAMKAKIIAHPHYSTLLQAYLDCQKIGA-----PP-DVVDRITAASRDPE-LDQFMEAYCDMLVKYREELTRPI----QEAMEFIRRIESQLSMLDRELKNHLLKKYSGYLSSLKQELSKKKKKGKLPKEARQKLLTWWELHYKWPYPSESEKVALAESTGLDQKQINNWFINQRKRHWKPS [173] OSH15 -EAESIKAKIMAHPQYSALLAAYLDCQKVGA-----PP-EVLERLTATARDPE-LDQFMEAYCNMLAKYREELTRPI----DEAMEFLKRVESQLDTIDKELKFQLLKKYSGYLSSLRQEFSKKKKKGKLPKEARQKLLHWWELHYKWPYPSETEKIALAESTGLDQKQINNWFINQRKRHWKPS [173] RS1 -EAEAIKAKIVAHPQYSALLAAYLDCQKVGA-----PP-DVLERLTAMPRDPE-LDQFMEAYCNMLVKYREELTRPI----DEAMEFLKRVEAQLDCIDKELKYQLLKKYSGYLSSLRQEFSKKKKKGKLPKEARQKLLHWWELHYKWPYPSETEKIALAESTGLDQKQINNWFINQRKRHWKPS [173] OSH43 -AEAAVKAEIMSHPQYSALLAAYLGCKKVGA-----PP-DVLTKLTAVDDDPDQLDQFMDAYCSMLTRYREELERPI----LEAAEFFSRVETQLDSLDKQLKHQLLRKYGGSLGDLRQVFSKRTKKGKLPKEARQKLLHWWELHYKWPYPSEMEKMTLAQTTGLDQKQINNWFINQRKRHWKPT [174] SKN1 -EEYAIKSKILAHPQYPSLLGAYIDCQKIGA-----PP-EAVARLDALGMDPE-LDQFMEAYCEILTKYHEELAKPF----KEAMTFLMKIEAQFNSLDRELKDHLLRRYSGYLSSLKQEFMKKKKKGKLPKDARQKLLDWWSLHDKWPYPSETEKIALAECTGLDQKQINNWFINQRKRHWKPS [173] SKN2 -EAEAIKAKILAHPQYPSLLGAYIDCQKIGA-----PP-EVVARLDALGMDPE-LDQFMEAYCEMLTKYHEELTKPF----KEAMSFLKKIEAQLNSLDRELKDHLLRKYSGYLSSLKQEFMKKKKKGKLPKDARQKLLDWWTVHYKWPYPSETEKIALAECTGLDQKQINNWFINQRKRHWKPS [173] OSH3 -LDDPVKARIVSHPRYHRLLAAFLDCHKVGC-----PA-EAAEEIAAAPEDPE-LKLVTEDYCKLLVECKEELSRPL----QEAEEFLRTVESELELNDKALKRHLLRKYSGYLGGLRKELSKKRKKGKLPKEARQKLLTWWELHYRWPNPSEMEKIALAESTGLEQKQINNCFINQRKRHWKPT [173] SkKNOX1 -ESEMLRAAIVSHPHYPELVVAHMNCHKVAA-----SP-EVVSQIDEIGANPE-LDQFMVAYYSMLLKCEKEVRKTF----KEAVAFCKKLDQQFQVIDKELKEQLMRKYSGYISSLKHEFLKKKKKGKLPKDSRQILLNWWSVHYKWPYPSESEKASLAESTGLDQKQINNWFINQRKRHWKPS [173] SkKNOX2 -EKEMK-AAISGHPQYLELIKAHMSIKKVGA-----SS-QKVAEINEVGANPE-LDQFMVAYCDVLNMYENQLNKAF----TGAIEYCKQQEQELKLVDKEIKRALMKKYGGYLGGLTQEYLKKKKKSKLPSAATKTLRDWWFQHLEHPYPSEAQKATLAATTKLDPKQINNWFINQRKRHWDPS [172] MKN2 -QDLELRAAIIDHPFYPEMVLAHVRVFKIGA-----PG-RLRRKLDELGSDPE-LDHF?RSYVGVLTKFAEDLEEPF----NKFIQFTDNTSKALEEIDEDIKKALRKKYGRHIGELKAEFNRVRKKGKLPTSARTILKDWFNRHSHWPYPSEMEKQYLQRICGLNLKQINNWFINERKRHWSCE [173] MKN4 -EEQLLRDAIVDHPLYPELVVAHISIFKIGA-----PK-GLLIKLDEMGQDPS-LDFFMRSYIDLLTKFREDLENPY----NKFAQYKDKVTKDLEDLDEELKKMLRLKYGKHIAGLKAEFNRVRKKGKLPTNARQILKDWFSRHSYWPYPSEMEKAYLQRLCGLNLKQINNWFINERKRHWSCK [173] Bnhd1 -QNRQMKGEIATHPMYDQLLAAHVACLRVATPIDQLPIIEAQLSHSHHHDRQE-LDNFLAQYVMVLCSFKEQLQQHVRVHAVEAVMACREIENNLHSLRQELKLELKQGFKSRIEDVREEIMRKRRAGKLPGDTTTVLKNWWQQHCKWPYPTEDDKAKLVEETGLQLKQINNWFINQRKRNWHNN [183] KNAT7 -QNRQLKGEIATHPMYEQLLAAHVACLRVATPIDQLPIIEAQLSQSHHHDRHE-LDNFLAQYVMVLCSFKEQLQQHVRVHAVEAVMACREIENNLHSLRQELKLELKQGFKSRIEDVREEIMRKRRAGKLPGDTTTVLKNWWQQHCKWPYPTEDDKAKLVEETGLQLKQINNWFINQRKRNWHNN [183] THox2 -HYNQLKSEIATHPLYEQLLSAHVACLRVRTPIDQLPLIDAQLTQSHNHERQE-LDNFLAQYLLVLCSFKEQLQQHVRVHAVEAVMACREIEQNLQLLRQELKIELKQGFRSRIEDVREEILRKRRAGKLPGDTTTVLKNWWQQHSKWPYPTEDDKAKLVEETGLQLKQINNWFINQRKRNWHSN [183] HOS66 -ERQLLKGEIAVHPLCEQLVAAHVGCLRVATPIDHLPLIDAQLAQSSGHDKQE-LDSFLAQYMMLLCSFREQLQQHVRVHAVEAVMACREIEQSLQDLRQELKIELKQGFKSRIEDVREEILRKRRAGKLPGDTTTILKQWWQQHSKWPYPTEDDKAKLVEETGLQLKQINNWFINQRKRNWHNN [183] CRKNOX3 -QNARLKADITMHPLYDQLLAAHVACLRIATPVDQLPRIDAQIAQASQEEKDE-LDQFMAHYVLLLCTFKEQLQQHVKVHAMEAVMACWELEQSLLTLRQELKNELKNGYKDRIVDVREEILRKRRAGKLPGDTTSVLKAWWHAHSKWPYPTEDEKARLVQETGLQLKQINNWFINQRKRNWHSN [183] HOS59 -GWEREKAAIAAHPLYERLLEAHVACLRVATPVDQLPRIDAQIAARPPSGGEE-LDLFMTHYVLLLCSFKEQLQQHVRVHAMEAVMACWELEQTLQSLRQELKHELKQGYREKLVDIREEILRKRRAGKLPGDTASTLKAWWQAHSKWPYPTEEDKARLVQETGLQLKQINNWFINQRKRNWHSN [183] OSH45 -DAARCKAEILAHPLYEQLLSAHVACLRIATPVDQLPRIDAQLAQSQGDDGRE-LDQFMTHYVLLLCSFKEQLQQHVRVHAMEAVMACWELEQNLQSLRQELKHELKQGYKEKLIDIREEILRKRRAGKLPGDTTSTLKAWWQSHAKWPYPTEEDKARLVQETGLQLKQINNWFINQRKRNWHSN [183] LET12 -EREKCKADILNHPLYDQLLSAHVSCLRIATPVDQLPRIDAQLAQSQNLDDKD-LDQFMTHYVLLLSSFKEQLQQHVRVHAMEAVMACWELEQSLQSLRQELKHELKQGYKEKIVDIREEILRKRRAGKLPGDTTSVLKAWWQSHSKWPYPTEEDKARLVQETGLQLKQINNWFINQRKRNWHSN [183] KNAT3 -QNARHKAEILSHPLYEQLLSAHVACLRIATPVDQLPRIDAQLAQSQHGDDKE-LDQFMTHYVLLLCSFKEQLQQHVRVHAMEAVMACWEIEQSLQSLRQELKHELKQGYKEKIVDIREEILRKRRAGKLPGDTTSVLKAWWQSHSKWPYPTEEDKARLVQETGLQLKQINNWFINQRKRNWHSN [183] KNAT4 -QNARHKAEILSHPLYEQLLSAHVACLRIATPVDQLPRIDAQLAQSQNGDDKE-LDHFMTHYVLLLCSFKEQLQQHVRVHAMEAVMACWEIEQSLQSFRQELKHELKQGYKEKIVDIREEILRKRRAGKLPGDTTSVLKSWWQSHSKWPYPTEEDKARLVQETGLQLKQINNWFINQRKRNWHSN [183] KNAP3 -QNARHKAEILAHPLYEPLLSAHVACLRIATPVDQLPRIDAQLAQSQNGDDKE-LDQFMRNYVLLLCSFKEQLQQHVRVHAMEAVMACWEIEQSLQSLRQELKHELKQGYKEKIVDIREEILRKRRAGKLPGDTTSVLKAWWQSHSKWPYPTEEDKARLVQETGLQLKQINNWFINQRKRNWHSN [183] NTH23 -QNAGYKAEILAHPLFEQLLSAHVACLRIATPVDQLPRIDAQLAQSQQGDDKE-LDQFLTHYVLLLCPFKEQLQQHVRVHAMEAVMACWEIEQSLQSLRQELKHDLKQGYKEKLVDIREEILRKRRAGKLPGDTTSVLKAWWQSHAKWPYPTEEDKAKLVQETGLQLKQINNWFINQRKRDWHSN [183] 'MKN1-3' -EQARDKFLIVAHPLYPDLLNAHASCLRVGTPVDQLPHIEAQLTQARHDEKTE-LDQFMAQYIMLLCSFKDHLQQHVYYDVTEAMMSCWELEQALHNLRQELKYELKQGYRARIVDVREEILRKRRAGKLPEGTTTVLKAWWQAHSKWPYPTEDEKERRIQETGLELKQVNNWFINQRKRNWHSN [183] KNAT5 -RSASYKAAILRHPMYEQLLAAHVACLRVATPVDQIPRIDAQLSQLHTVDNKE-LDHFMSHYVVLLCSFKEQLQHHVCVHAMEAITACWEIEQSLQSLKKELKHELKQGFKEKIVDIREEIMRKRRAGKLPGDTTSVLKEWWRTHSKWPYPTEEDKAKLVQETGLQLKQINNWFINQRKRNWNSN [183] AaKNOX1 -MLSDMGEQVIMHPLYPDLVKAIMDCRKVGGMDESRHHIQIRTEQVLE--DPE-LDQFLRQYIQVLDELHAELLNINREADNILHMFTTQIAEVINMPEQEQRVLLKQKYRQELLALKEEFSKRKKRGKLPTHSIEVLKSWWKEHIAWPYPTDSAKRSLASQTNLTSIQINNWFINQRKRHWHKL [181] BELL1 ----------------------------------------------------E-LQKRKAKLLSMLEELKRRYGHYREQMRVAAAAFEAAVG-----LRLRLLDQALRQQKSYRQMTLVDAHPWRPQRGLPERAVTTLRAWLFEHFLHPYPSDVDKHILARQTGLSRSQVSNWFINARVRLWKPM [127] H1 ----------------------------------------------------A-KKTHLLDLLQMVDDRYSHCVDEIHTVISAFHAATELDPQLHTRFDKTQETSMFHQHCLLQQLKRKNHQIWRPQRGLPEKSVSVLRNWMFQNFLHPYPKDSEKHLLAIRSGLTRSQVSNWFINARVRLWKPM [132]