Supplementary material for Jiang et al. (2001) Proc. Natl. Acad. Sci. USA 98 (4), 19301934. (10.1073/pnas.041579198)
Table 4.
Gene expression changes in the cortex from young (2 months) and old (22 months) BALB/c miceAccession no. | Gene name | Fold change |
M21285 | Stearoyl-CoA desaturase | 2.4 |
AA030066 | Translation factor Sui1 | 2.2 |
AA107514 | Translation factor Sui1 like protein | 10.6 |
X06407 | 21 kd polypeptide under translational control | 3.1 |
AA060550 | Cyclophilin; cyclosporin A-binding protein | 2.8 |
AA124572 | Cyclophilin like protein | 2.5 |
X60672 | Radixin, cytoskeletal-membrane linker protein | 4.9 |
AA168959 | 25 kDa FK506 binding protein FKBP25 | 2.7 |
U27315 | Adenine nucleotide translocase-1 | 2.2 |
AA087787 | Ribosomal protein L5 | 2.7 |
X99807 | Selenoprotein P | 2.2 |
U95116 | Lissencephaly-1 protein | 2.6 |
AA106783 | Poly(A) binding protein | 2.8 |
L32372 | AMPA receptor subunit (GluR-B) | 2.8 |
D21252 | mRNA for OSF-3 | 2.1 |
U09010 | Mannose-binding protein (MBP) | 4.1 |
W41861 | gC1qBP, 33 kDa globular 'heads' of C1q binding protein | 2.3 |
L20899 | Cell division cycle (CDC25) | 2.6 |
M13500 | Kallikrein gene mGK-6 | 5.2 |
M60474 | Myristoylated alanine-rich C kinase substrate | 2.2 |
X06746 | Zinc finger protein, activated during G0/G1 transition | 2.7 |
X51438 | Vimentin, cytoskeletal protein | 3.2 |
X54149 | MyD118, a myeloid differentiation primary response gene | 2.1 |
X60289 | Ribosomal protein S24 | 2.1 |
X61232 | Carboxypeptidase H | 3.6 |
X92665 | Ubiquitin-conjugating enzyme UbcM3 | 3 |
AA013993 | Prolyl oligopeptidase | 2.7 |
AA020512 | Caspase 6 | 2.2 |
X65582 | Alpha-2 collagen VI | 2.1 |
X74855 | Kruppel-like zinc finger protein, transcription repressor | 3.1 |
X77731 | Deoxycytidine kinase | 3 |
X78684 | B-cell receptor associated protein | 2 |
X79082 | MDK1, a receptor tyrosine kinase | 2 |
X80232 | SIG41, splicing regulator | 2.1 |
Z11664 | Son of sevenless 2 | 2.9 |
Z30970 | Metalloproteinase-3 tissue inhibitor | 2.1 |
Z37110 | Cyclin G, enhance apoptotic cell death | 2.8 |
AA590859 | A-X actin like protein | 7.3 |
AA709861 | A-X actin like protein | 7.4 |
J04181 | A-X actin | 3.6 |
C76314 | Cdc5-like protein | 2.4 |
M84145 | Fumarylacetoacetate hydrolase | 3.1 |
U70494 | Histone H2A.Z | 2.4 |
D37792 | Synaptotagmin I | -13.2 |
M73490 | Apolipoprotien E | -6.9 |
U27106 | Clathrin-associated AP-2 | -5.5 |
AA050852 | Nucleoside diphosphate kinase A | -3 |
AA124955 | Casein kinase 1 alpha | -2.9 |
X69025 | PCTAIRE-1 protein kinase, Cdk family | -2.1 |
Z67745 | Phosphatase 2A catalytic subunit | -6.2 |
M27073 | Protein phosphatase 1 beta | -2.7 |
J02626 | cAMP-dependent protein kinase C beta | -4.6 |
AA289338 | cAMP-regulated phosphoprotein | -2.2 |
D28117 | Magnesium dependent protein phosphatase | -3.2 |
AA117812 | Cell division cycle 10 | -3.1 |
W97055 | Beta-4-tubulin | -2.4 |
AA118546 | Actin like protein 3 | -6.2 |
U13841 | ATPase subunit E | -4.4 |
AA105755 | Na+,K+-ATPase alpha | -4.6 |
AA003458 | Sarco/endoplasmic reticulum Ca2+ -ATPase | -5.9 |
X56007 | Na/K-ATPase beta 2 subunit | -2.3 |
AA106307 | H(+)-ATPase E like protein | -3.8 |
AA139602 | C7-1, H+ ATPase like protein | -9.2 |
AA050703 | Defender against death 1 (DAD1) | -2.4 |
X14425 | Profilin, promote actin polymerization | -3.5 |
AA097524 | Phosphoglycerate kinase | -3.9 |
AA105022 | Heat-shock protein hsp84 like protein | -2.7 |
AA204094 | HSP40/DNAJ homolog | -2.9 |
AA109714 | Ubiquitin ligase Skp1 | -2.3 |
W18503 | Dynein heavy chain, retrograde transport | -7.7 |
AA111631 | Dynactin 1, retrograde axonal transport | -3.4 |
W41762 | RAS-related protein RAB-14 | -2.2 |
X95403 | GTP-binding protein; rab2 | -2.7 |
M76131 | Elongation factor 2 | -4.7 |
AA145945 | Elongation factor-1-gamma | -3.6 |
AA008667 | Translation initiation factor 4 | -2.7 |
AA028398 | Beta tubulin | -2.1 |
AA016564 | Insulin-induced growth-respons protein, splicing regulator | -2.7 |
W13835 | N-ethylmaleimide-sensitive membrane protein homolog | -3.2 |
U10120 | N-ethylmaleimide sensitive factor | -10.3 |
X07699 | Nucleolin, rRNA processing | -2.9 |
X59520 | Cholecystokinin (CCK) | -2.1 |
AA389346 | Citrate synthase | -3.4 |
AB006361 | Prostaglandin D synthetase | -3.2 |
AA560856 | Aconitase | -4.9 |
AA592283 | N-ras related gene | -3.3 |
AF026124 | Schwannoma-associated protein (SAM9) | -2.4 |
AJ001118 | Monoglyceride lipase | -4.6 |
D38614 | 921-S, presynaptic protein | -5.1 |
D78643 | Ornithine decarboxylase antizyme 2 | -2.7 |
L25126 | RNA helicase | -2.5 |
L31397 | Dynamin | -2.7 |
M27844 | Calmodulin | -2.7 |
M31811 | Myelin associated-glycoprotein | -3.2 |
M63436 | GABA-A receptor alpha-1 subunit | -7.1 |
U00689 | RNA binding protein TIA-1 | -2.9 |
U09383 | Calcium-activated potassium channel | -3 |
U62021 | EB1 homolog, microtubule associated protein | -4.8 |
Each RNA sample was hybridized twice to two different arrays, and fold change values are averages of the duplicate measurements.