Blood, Vol. 116, Issue 9, 1585-1592, September 2, 2010

Identification of a PRMT5-dependent repressor complex linked to silencing of human fetal globin gene expression
Blood Rank et al. 116: 1585

Supplemental materials for: Rank et al

Files in this Data Supplement:

• Figure S1. Binding of the PRMT5-dependent complex components across the γ-gene by ChIP assays (JPG, 190 KB) -
  Chromatin fractions from K562 cells were immunoprecipitated with the listed Abs, and amplified with primer pairs spanning the indicated regions of the γ-promoter (P-3 to P-1) and γ-gene (P+1 and P+2)⁸. The positions of the regions relative to the transcriptional start site are provided. Normal rabbit IgG served as the control.
  
  
  
  
  
  
• Figure S2. H4K20me3 at the γ-promoter was measured by ChIP in chromatin fractions from erythroid progenitors from CB and BM (JPG, 38.4 KB) -